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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56150553
log Bayes Factor = 20.6531
Chromosome 17   position 73,389,145  (GRCh37) Explore rs56150553 on Ensembl!
Variant rs56150553 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N17-N19 Renal failure
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I25.2 Old myocardial infarction
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
I44 Atrioventricular and left bundle-branch block
0.996 0.004 0.000
E86 Volume depletion
0.996 0.004 0.000
N17 Acute renal failure
0.994 0.006 0.000
I44.0 Atrioventricular block, first degree
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
N17.9 Acute renal failure, unspecified
0.989 0.011 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
M06 Other rheumatoid arthritis
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
N18 Chronic renal failure
0.985 0.015 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.981 0.019 0.000
M80-M85 Disorders of bone density and structure
0.980 0.020 0.000
I77 Other disorders of arteries and arterioles
0.978 0.022 0.000
M06.9 Rheumatoid arthritis, unspecified
0.977 0.023 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.974 0.026 0.000
N30-N39 Other diseases of urinary system
0.973 0.027 0.000
I46 Cardiac arrest
0.971 0.029 0.000
E11 Non-insulin-dependent diabetes mellitus
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.966 0.034 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.966 0.034 0.000
D50-D53 Nutritional anaemias
0.963 0.037 0.000
G57 Mononeuropathies of lower limb
0.960 0.040 0.000
N30 Cystitis
0.960 0.040 0.000
F20 Schizophrenia
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.951 0.049 0.000
E11.4 With neurological complications
0.949 0.051 0.000
H43-H45 Disorders of vitreous body and globe
0.949 0.051 0.000
G57.6 Lesion of plantar nerve
0.948 0.052 0.000
D50 Iron deficiency anaemia
0.947 0.053 0.000
N18.3 Chronic kidney disease, stage 3
0.946 0.054 0.000
M20-M25 Other joint disorders
0.943 0.057 0.000
H35 Other retinal disorders
0.941 0.059 0.000
N30.8 Other cystitis
0.939 0.061 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.938 0.062 0.000
R30-R39 Symptoms and signs involving the urinary system
0.938 0.062 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.937 0.063 0.000
M20.5 Other deformities of toe(s) (acquired)
0.934 0.066 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.932 0.068 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
R33 Retention of urine
0.928 0.072 0.000
S80-S89 Injuries to the knee and lower leg
0.926 0.074 0.000
I46.9 Cardiac arrest, unspecified
0.925 0.075 0.000
S50-S59 Injuries to the elbow and forearm
0.924 0.076 0.000
M80 Osteoporosis with pathological fracture
0.924 0.076 0.000
L40-L45 Papulosquamous disorders
0.923 0.077 0.000
D50.9 Iron deficiency anaemia, unspecified
0.921 0.079 0.000
M20 Acquired deformities of fingers and toes
0.921 0.079 0.000
I22 Subsequent myocardial infarction
0.920 0.080 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.919 0.081 0.000
H43 Disorders of vitreous body
0.918 0.082 0.000
N18.9 Chronic renal failure, unspecified
0.917 0.083 0.000
I24 Other acute ischaemic heart diseases
0.914 0.086 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.913 0.087 0.000
I77.8 Other specified disorders of arteries and arterioles
0.909 0.091 0.000
R30 Pain associated with micturition
0.908 0.092 0.000
I74 Arterial embolism and thrombosis
0.908 0.092 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.907 0.093 0.000
F20.9 Schizophrenia, unspecified
0.906 0.094 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.903 0.097 0.000
M11 Other crystal arthropathies
0.903 0.097 0.000
R32 Unspecified urinary incontinence
0.902 0.098 0.000
N00-N08 Glomerular diseases
0.902 0.098 0.000
T66-T78 Other and unspecified effects of external causes
0.902 0.098 0.000
M81 Osteoporosis without pathological fracture
0.900 0.100 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.899 0.101 0.000
S00-S09 Injuries to the head
0.894 0.106 0.000
F25 Schizoaffective disorders
0.891 0.109 0.000
R30.0 Dysuria
0.890 0.110 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
E10 Insulin-dependent diabetes mellitus
0.887 0.113 0.000
H35.9 Retinal disorder, unspecified
0.883 0.117 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.883 0.117 0.000
D50.8 Other iron deficiency anaemias
0.879 0.121 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.872 0.128 0.000
I25.3 Aneurysm of heart
0.872 0.128 0.000
F30-F39 Mood [affective] disorders
0.871 0.129 0.000
F20.0 Paranoid schizophrenia
0.871 0.129 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.869 0.131 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.866 0.134 0.000
M05 Seropositive rheumatoid arthritis
0.865 0.135 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.863 0.137 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.863 0.137 0.000
I46.0 Cardiac arrest with successful resuscitation
0.861 0.139 0.000
H43.8 Other disorders of vitreous body
0.861 0.139 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.859 0.141 0.000
N30.3 Trigonitis
0.857 0.143 0.000
I44.2 Atrioventricular block, complete
0.857 0.143 0.000
M22 Disorders of patella
0.856 0.144 0.000
M86-M90 Other osteopathies
0.856 0.144 0.000
D80-D89 Certain disorders involving the immune mechanism
0.853 0.147 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.852 0.148 0.000
H65-H75 Diseases of middle ear and mastoid
0.852 0.148 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.850 0.150 0.000
G70-G73 Diseases of myoneural junction and muscle
0.848 0.152 0.000
D73 Diseases of spleen
0.848 0.152 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.846 0.154 0.000
I45 Other conduction disorders
0.844 0.156 0.000
L60-L75 Disorders of skin appendages
0.844 0.156 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.843 0.157 0.000
I77.1 Stricture of artery
0.843 0.157 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.840 0.160 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.840 0.160 0.000
H00 Hordeolum and chalazion
0.838 0.162 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.838 0.162 0.000
E11.2 With renal complications
0.836 0.164 0.000
M11.2 Other chondrocalcinosis
0.836 0.164 0.000
I33 Acute and subacute endocarditis
0.835 0.165 0.000
N18.0 End-stage renal disease
0.834 0.166 0.000
H35.6 Retinal haemorrhage
0.831 0.169 0.000
N17.0 Acute renal failure with tubular necrosis
0.831 0.169 0.000
H21 Other disorders of iris and ciliary body
0.830 0.170 0.000
L43 Lichen planus
0.829 0.171 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.828 0.172 0.000
E88 Other metabolic disorders
0.825 0.175 0.000
L20-L30 Dermatitis and eczema
0.824 0.176 0.000
F29 Unspecified nonorganic psychosis
0.823 0.177 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.823 0.177 0.000
S51 Open wound of forearm
0.823 0.177 0.000
L40 Psoriasis
0.823 0.177 0.000
H34 Retinal vascular occlusions
0.822 0.178 0.000
M91-M94 Chondropathies
0.821 0.179 0.000
H80-H83 Diseases of inner ear
0.821 0.179 0.000
I25.4 Coronary artery aneurysm
0.820 0.180 0.000
H04 Disorders of lachrymal system
0.819 0.181 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.817 0.183 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.816 0.184 0.000
E11.3 With ophthalmic complications
0.815 0.185 0.000
S82 Fracture of lower leg, including ankle
0.813 0.187 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.813 0.187 0.000
F31 Bipolar affective disorder
0.812 0.188 0.000
H36 Retinal disorders in diseases classified elsewhere
0.811 0.189 0.000
I34 Nonrheumatic mitral valve disorders
0.809 0.191 0.000
R41.0 Disorientation, unspecified
0.805 0.195 0.000
F25.9 Schizoaffective disorder, unspecified
0.805 0.195 0.000
H55-H59 Other disorders of eye and adnexa
0.804 0.196 0.000
M81.4 Drug-induced osteoporosis
0.803 0.197 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.803 0.197 0.000
G57.1 Meralgia paraesthetica
0.802 0.198 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.801 0.199 0.000
S81 Open wound of lower leg
0.800 0.200 0.000
D53 Other nutritional anaemias
0.799 0.201 0.000
E83 Disorders of mineral metabolism
0.799 0.201 0.000
M60-M63 Disorders of muscles
0.798 0.201 0.000
N30.4 Irradiation cystitis
0.797 0.203 0.000
T78 Adverse effects, not elsewhere classified
0.797 0.203 0.000
R34 Anuria and oliguria
0.797 0.203 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.796 0.204 0.000
Chapter XX External causes of morbidity and mortality
0.795 0.205 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.794 0.206 0.000
I60-I69 Cerebrovascular diseases
0.794 0.206 0.000
M06.3 Rheumatoid nodule
0.794 0.206 0.000
I72 Other aneurysm
0.792 0.208 0.000
I44.3 Other and unspecified atrioventricular block
0.792 0.208 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.790 0.210 0.000
D72 Other disorders of white blood cells
0.790 0.210 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.790 0.210 0.000
F23 Acute and transient psychotic disorders
0.790 0.210 0.000
H00.1 Chalazion
0.788 0.212 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.787 0.213 0.000
H60-H62 Diseases of external ear
0.787 0.213 0.000
G56 Mononeuropathies of upper limb
0.787 0.213 0.000
L50-L54 Urticaria and erythema
0.786 0.214 0.000
T92 Sequelae of injuries of upper limb
0.786 0.214 0.000
M21 Other acquired deformities of limbs
0.786 0.214 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.785 0.215 0.000
M22.2 Patellofemoral disorders
0.785 0.215 0.000
M31 Other necrotising vasculopathies
0.784 0.216 0.000
I23 Certain current complications following acute myocardial infarction
0.783 0.217 0.000
H43.3 Other vitreous opacities
0.783 0.217 0.000
I77.0 Arteriovenous fistula, acquired
0.782 0.217 0.000
E13 Other specified diabetes mellitus
0.782 0.218 0.000
E10.9 Without complications
0.780 0.220 0.000
M14 Arthropathies in other diseases classified elsewhere
0.780 0.220 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.780 0.220 0.000
A30-A49 Other bacterial diseases
0.779 0.221 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.779 0.221 0.000
Chapter XXII Codes for special purposes
0.779 0.221 0.000
G57.5 Tarsal tunnel syndrome
0.779 0.221 0.000
B00 Herpesviral [herpes simplex] infections
0.778 0.222 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.778 0.222 0.000
I44.1 Atrioventricular block, second degree
0.777 0.223 0.000
B02 Zoster [herpes zoster]
0.777 0.223 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.777 0.223 0.000
D73.0 Hyposplenism
0.777 0.223 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.775 0.225 0.000
S09 Other and unspecified injuries of head
0.772 0.228 0.000
E78.5 Hyperlipidaemia, unspecified
0.771 0.229 0.000
H66 Suppurative and unspecified otitis media
0.771 0.229 0.000
N18.5 Chronic kidney disease, stage 5
0.771 0.229 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.770 0.230 0.000
S82.0 Fracture of patella
0.770 0.230 0.000
G50 Disorders of trigeminal nerve
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.769 0.231 0.000
N19 Unspecified renal failure
0.768 0.232 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.768 0.232 0.000
E10.2 With renal complications
0.768 0.232 0.000
N25-N29 Other disorders of kidney and ureter
0.765 0.235 0.000
L29 Pruritus
0.762 0.238 0.000
T23 Burn and corrosion of wrist and hand
0.761 0.239 0.000
L43.9 Lichen planus, unspecified
0.761 0.239 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.761 0.239 0.000
N34 Urethritis and urethral syndrome
0.761 0.239 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.761 0.239 0.000
S06 Intracranial injury
0.759 0.241 0.000
S56 Injury of muscle and tendon at forearm level
0.757 0.243 0.000
E14 Unspecified diabetes mellitus
0.755 0.245 0.000
H81 Disorders of vestibular function
0.755 0.245 0.000
H35.3 Degeneration of macula and posterior pole
0.755 0.245 0.000
N99-N99 Other disorders of the genitourinary system
0.753 0.247 0.000
I44.7 Left bundle-branch block, unspecified
0.752 0.248 0.000
S05 Injury of eye and orbit
0.751 0.249 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
H35.2 Other proliferative retinopathy
0.749 0.251 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.749 0.251 0.000
N05 Unspecified nephritic syndrome
0.749 0.251 0.000
H35.8 Other specified retinal disorders
0.748 0.252 0.000
D55-D59 Haemolytic anaemias
0.747 0.253 0.000
M07 Psoriatic and enteropathic arthropathies
0.747 0.253 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.746 0.254 0.000
H04.9 Disorder of lachrymal system, unspecified
0.744 0.256 0.000
D86 Sarcoidosis
0.744 0.256 0.000
T20 Burn and corrosion of head and neck
0.743 0.257 0.000
H49 Paralytic strabismus
0.741 0.259 0.000
H50 Other strabismus
0.741 0.259 0.000
I74.8 Embolism and thrombosis of other arteries
0.741 0.259 0.000
M80.8 Other osteoporosis with pathological fracture
0.741 0.259 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.740 0.260 0.000
S82.00 Fracture of patella (closed)
0.738 0.262 0.000
R40 Somnolence, stupor and coma
0.737 0.263 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.737 0.263 0.000
E11.1 With ketoacidosis
0.736 0.264 0.000
H10-H13 Disorders of conjunctiva
0.736 0.264 0.000
M85 Other disorders of bone density and structure
0.735 0.265 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.734 0.266 0.000
H66.9 Otitis media, unspecified
0.733 0.267 0.000
M32 Systemic lupus erythematosus
0.731 0.268 0.000
M86 Osteomyelitis
0.731 0.269 0.000
G35 Multiple sclerosis
0.731 0.269 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.730 0.270 0.000
I25.5 Ischaemic cardiomyopathy
0.730 0.270 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.729 0.271 0.000
I25.1 Atherosclerotic heart disease
0.729 0.271 0.000
H43.1 Vitreous haemorrhage
0.729 0.271 0.000
Q43 Other congenital malformations of intestine
0.729 0.271 0.000
N60-N64 Disorders of breast
0.726 0.274 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.725 0.275 0.000
H65 Nonsuppurative otitis media
0.724 0.276 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.724 0.276 0.000
L60 Nail disorders
0.723 0.277 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.723 0.277 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.722 0.278 0.000
S83.2 Tear of meniscus, current
0.721 0.279 0.000
L29.0 Pruritus ani
0.721 0.279 0.000
S20-S29 Injuries to the thorax
0.720 0.280 0.000
E74 Other disorders of carbohydrate metabolism
0.720 0.280 0.000
I34.0 Mitral (valve) insufficiency
0.720 0.280 0.000
I33.0 Acute and subacute infective endocarditis
0.720 0.280 0.000
S31 Open wound of abdomen, lower back and pelvis
0.720 0.280 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.719 0.281 0.000
E85 Amyloidosis
0.718 0.282 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
S51.0 Open wound of elbow
0.717 0.283 0.000
I61 Intracerebral haemorrhage
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
G57.8 Other mononeuropathies of lower limb
0.716 0.284 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I44.5 Left posterior fascicular block
0.714 0.286 0.000
I44.4 Left anterior fascicular block
0.714 0.286 0.000
M84 Disorders of continuity of bone
0.713 0.287 0.000
N17.8 Other acute renal failure
0.713 0.287 0.000
N17.2 Acute renal failure with medullary necrosis
0.713 0.287 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
E78.1 Pure hyperglyceridaemia
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
F52.2 Failure of genital response
0.711 0.289 0.000
S54 Injury of nerves at forearm level
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.710 0.290 0.000
N30.2 Other chronic cystitis
0.708 0.292 0.000
B02.9 Zoster without complication
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.707 0.292 0.000
M06.2 Rheumatoid bursitis
0.707 0.292 0.000
M06.1 Adult-onset Still's disease
0.707 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
E10.5 With peripheral circulatory complications
0.707 0.293 0.000
N18.1 Chronic kidney disease, stage 1
0.706 0.293 0.000
M34 Systemic sclerosis
0.705 0.295 0.000
M81.2 Osteoporosis of disuse
0.704 0.296 0.000
I77.6 Arteritis, unspecified
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
S00 Superficial injury of head
0.704 0.296 0.000
A15-A19 Tuberculosis
0.704 0.296 0.000
F28 Other nonorganic psychotic disorders
0.703 0.296 0.000
F24 Induced delusional disorder
0.703 0.296 0.000
F21 Schizotypal disorder
0.703 0.296 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.703 0.297 0.000
M81.9 Osteoporosis, unspecified
0.703 0.297 0.000
R21 Rash and other nonspecific skin eruption
0.703 0.297 0.000
M83 Adult osteomalacia
0.703 0.297 0.000
M82 Osteoporosis in diseases classified elsewhere
0.703 0.297 0.000
M22.3 Other derangements of patella
0.702 0.298 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.702 0.298 0.000
M10 Gout
0.702 0.298 0.000
F25.0 Schizoaffective disorder, manic type
0.701 0.299 0.000
I77.5 Necrosis of artery
0.701 0.299 0.000
I77.4 Coeliac artery compression syndrome
0.701 0.299 0.000
I77.3 Arterial fibromuscular dysplasia
0.701 0.299 0.000
I77.2 Rupture of artery
0.701 0.299 0.000
H36.0 Diabetic retinopathy
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.299 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.700 0.300 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.700 0.300 0.000
M06.0 Seronegative rheumatoid arthritis
0.700 0.300 0.000
T21 Burn and corrosion of trunk
0.700 0.300 0.000
G70 Myasthenia gravis and other myoneural disorders
0.700 0.300 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.699 0.301 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
I45.1 Other and unspecified right bundle-branch block
0.698 0.302 0.000
L84 Corns and callosities
0.698 0.302 0.000
M06.4 Inflammatory polyarthropathy
0.698 0.302 0.000
L40.5 Arthropathic psoriasis
0.698 0.302 0.000
A00-A09 Intestinal infectious diseases
0.697 0.303 0.000
N37 Urethral disorders in diseases classified elsewhere
0.697 0.303 0.000
N33 Bladder disorders in diseases classified elsewhere
0.697 0.303 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.697 0.303 0.000
I46.1 Sudden cardiac death, so described
0.696 0.304 0.000
E00-E07 Disorders of thyroid gland
0.696 0.304 0.000
R20 Disturbances of skin sensation
0.696 0.304 0.000
F34 Persistent mood [affective] disorders
0.696 0.304 0.000
L40.9 Psoriasis, unspecified
0.695 0.305 0.000
E11.7 With multiple complications
0.695 0.305 0.000
T68 Hypothermia
0.695 0.305 0.000
S51.9 Open wound of forearm, part unspecified
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
M31.3 Wegener's granulomatosis
0.694 0.306 0.000
I42 Cardiomyopathy
0.694 0.306 0.000
S52 Fracture of forearm
0.694 0.306 0.000
H31 Other disorders of choroid
0.693 0.307 0.000
H72 Perforation of tympanic membrane
0.693 0.307 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
I45.5 Other specified heart block
0.693 0.307 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.692 0.307 0.000
H30 Chorioretinal inflammation
0.692 0.307 0.000
G52 Disorders of other cranial nerves
0.692 0.308 0.000
M00-M03 Infectious arthropathies
0.691 0.308 0.000
T75 Effects of other external causes
0.691 0.309 0.000
I74.5 Embolism and thrombosis of iliac artery
0.690 0.310 0.000
T92.1 Sequelae of fracture of arm
0.690 0.310 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.689 0.311 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.688 0.312 0.000
G57.4 Lesion of medial popliteal nerve
0.688 0.312 0.000
G57.3 Lesion of lateral popliteal nerve
0.688 0.312 0.000
G57.2 Lesion of femoral nerve
0.688 0.312 0.000
G57.0 Lesion of sciatic nerve
0.688 0.312 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.688 0.312 0.000
E11.8 With unspecified complications
0.688 0.312 0.000
S82.5 Fracture of medial malleolus
0.688 0.312 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.687 0.312 0.000
F30 Manic episode
0.687 0.313 0.000
F20.8 Other schizophrenia
0.687 0.313 0.000
F20.6 Simple schizophrenia
0.687 0.313 0.000
F20.5 Residual schizophrenia
0.687 0.313 0.000
F20.4 Postschizophrenic depression
0.687 0.313 0.000
F20.3 Undifferentiated schizophrenia
0.687 0.313 0.000
F20.2 Catatonic schizophrenia
0.687 0.313 0.000
F20.1 Hebephrenic schizophrenia
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.686 0.314 0.000
M20.0 Deformity of finger(s)
0.686 0.314 0.000
S81.9 Open wound of lower leg, part unspecified
0.686 0.314 0.000
F99-F99 Unspecified mental disorder
0.686 0.314 0.000
E10.4 With neurological complications
0.685 0.315 0.000
S09.9 Unspecified injury of head
0.684 0.316 0.000
H18 Other disorders of cornea
0.684 0.316 0.000
A41 Other septicaemia
0.683 0.317 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.683 0.317 0.000
T95 Sequelae of burns, corrosions and frostbite
0.683 0.317 0.000
H20 Iridocyclitis
0.683 0.317 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.682 0.317 0.000
D53.9 Nutritional anaemia, unspecified
0.682 0.318 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.682 0.318 0.000
H34.2 Other retinal artery occlusions
0.682 0.318 0.000
I70 Atherosclerosis
0.682 0.318 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.682 0.318 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.680 0.320 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.680 0.320 0.000
D75 Other diseases of blood and blood-forming organs
0.680 0.320 0.000
E11.6 With other specified complications
0.679 0.320 0.000
D50.1 Sideropenic dysphagia
0.679 0.321 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.679 0.321 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.679 0.321 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.678 0.322 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.678 0.322 0.000
T78.8 Other adverse effects, not elsewhere classified
0.678 0.322 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.676 0.324 0.000
M33 Dermatopolymyositis
0.676 0.324 0.000
G72 Other myopathies
0.676 0.324 0.000
N18.2 Chronic kidney disease, stage 2
0.676 0.324 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.675 0.325 0.000
E10.6 With other specified complications
0.675 0.325 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.675 0.325 0.000
H35.1 Retinopathy of prematurity
0.674 0.325 0.000
G56.0 Carpal tunnel syndrome
0.675 0.325 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.674 0.326 0.000
E83.5 Disorders of calcium metabolism
0.674 0.326 0.000
R40.2 Coma, unspecified
0.673 0.327 0.000
G58 Other mononeuropathies
0.672 0.327 0.000
R36 Urethral discharge
0.672 0.328 0.000
I31 Other diseases of pericardium
0.672 0.328 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.671 0.328 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.672 0.328 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.671 0.329 0.000
D73.8 Other diseases of spleen
0.671 0.329 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
D72.8 Other specified disorders of white blood cells
0.669 0.331 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.333 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.333 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.333 0.000
I45.9 Conduction disorder, unspecified
0.667 0.333 0.000
H50.1 Divergent concomitant strabismus
0.667 0.333 0.000
E65-E68 Obesity and other hyperalimentation
0.666 0.334 0.000
R23 Other skin changes
0.665 0.335 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.664 0.336 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.664 0.336 0.000
S88 Traumatic amputation of lower leg
0.664 0.336 0.000
S87 Crushing injury of lower leg
0.664 0.336 0.000
S86 Injury of muscle and tendon at lower leg level
0.664 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.664 0.336 0.000
S84 Injury of nerves at lower leg level
0.664 0.336 0.000
T93 Sequelae of injuries of lower limb
0.664 0.336 0.000
N64 Other disorders of breast
0.663 0.337 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.337 0.000
I24.8 Other forms of acute ischaemic heart disease
0.663 0.337 0.000
E11.0 With coma
0.663 0.337 0.000
S59 Other and unspecified injuries of forearm
0.663 0.337 0.000
S58 Traumatic amputation of forearm
0.663 0.337 0.000
S57 Crushing injury of forearm
0.663 0.337 0.000
S55 Injury of blood vessels at forearm level
0.663 0.337 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.663 0.337 0.000
M89 Other disorders of bone
0.663 0.337 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.662 0.337 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.662 0.337 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.662 0.337 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.662 0.337 0.000
L44 Other papulosquamous disorders
0.662 0.338 0.000
L41 Parapsoriasis
0.662 0.338 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.662 0.338 0.000
L42 Pityriasis rosea
0.662 0.338 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.662 0.338 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.662 0.338 0.000
I44.6 Other and unspecified fascicular block
0.661 0.339 0.000
B02.3 Zoster ocular disease
0.660 0.340 0.000
G12 Spinal muscular atrophy and related syndromes
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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