TreeWAS – Variant ID: rs564398

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.000	0.000	1.000
H40.1 Primary open-angle glaucoma	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.000	1.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.000	1.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.000	1.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.000	1.000
C71 Malignant neoplasm of brain	1.000	0.000	0.000
H40 Glaucoma	0.000	0.000	1.000
I22 Subsequent myocardial infarction	0.000	0.000	1.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.000	1.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.000	1.000
I73 Other peripheral vascular diseases	0.000	0.000	1.000
I74 Arterial embolism and thrombosis	0.000	0.000	1.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.001	0.999
C71.9 Brain, unspecified	0.999	0.001	0.000
C71.1 Frontal lobe	0.998	0.002	0.000
I77 Other disorders of arteries and arterioles	0.000	0.004	0.996
I77.1 Stricture of artery	0.000	0.005	0.995
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.005	0.995
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.007	0.993
E11.9 Without complications	0.000	0.009	0.991
H40.0 Glaucoma suspect	0.000	0.015	0.985
I24 Other acute ischaemic heart diseases	0.000	0.015	0.985
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.018	0.982
I72 Other aneurysm	0.000	0.022	0.978
Chapter IX Diseases of the circulatory system	0.000	0.024	0.976
C71.3 Parietal lobe	0.974	0.026	0.000
C44 Other malignant neoplasms of skin	0.973	0.027	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.970	0.030	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.031	0.969
C15 Malignant neoplasm of oesophagus	0.963	0.037	0.000
C15-C26 Malignant neoplasms of digestive organs	0.962	0.038	0.000
C44.3 Skin of other and unspecified parts of face	0.962	0.038	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.957	0.043	0.000
Chapter II Neoplasms	0.954	0.046	0.000
C15.9 Oesophagus, unspecified	0.953	0.047	0.000
C44.0 Skin of lip	0.952	0.048	0.000
C15.5 Lower third of oesophagus	0.952	0.048	0.000
C44.5 Skin of trunk	0.951	0.049	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.052	0.948
E11.1 With ketoacidosis	0.000	0.055	0.945
I60-I69 Cerebrovascular diseases	0.000	0.056	0.944
I25.5 Ischaemic cardiomyopathy	0.000	0.061	0.939
C16 Malignant neoplasm of stomach	0.937	0.063	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.064	0.936
C44.1 Skin of eyelid, including canthus	0.931	0.069	0.000
C71.2 Temporal lobe	0.928	0.072	0.000
C71.0 Cerebrum, except lobes and ventricles	0.925	0.075	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.082	0.918
C16.0 Cardia	0.917	0.083	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.084	0.916
C71.8 Overlapping lesion of brain	0.913	0.087	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.091	0.909
I70 Atherosclerosis	0.000	0.094	0.906
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.095	0.905
I24.8 Other forms of acute ischaemic heart disease	0.000	0.096	0.904
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.097	0.903
I67 Other cerebrovascular diseases	0.000	0.098	0.902
I72.3 Aneurysm of iliac artery	0.000	0.099	0.901
I25.4 Coronary artery aneurysm	0.000	0.107	0.893
H40.8 Other glaucoma	0.000	0.112	0.888
I65.2 Occlusion and stenosis of carotid artery	0.000	0.113	0.887
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.116	0.884
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.119	0.881
I20.8 Other forms of angina pectoris	0.000	0.122	0.878
C21 Malignant neoplasm of anus and anal canal	0.869	0.131	0.000
I60 Subarachnoid haemorrhage	0.000	0.133	0.867
I67.9 Cerebrovascular disease, unspecified	0.000	0.134	0.866
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.865	0.135	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.142	0.858
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.145	0.855
I72.0 Aneurysm of carotid artery	0.000	0.157	0.843
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.157	0.842
E11.5 With peripheral circulatory complications	0.000	0.160	0.840
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.170	0.830
I25.3 Aneurysm of heart	0.000	0.173	0.827
I22.8 Subsequent myocardial infarction of other sites	0.000	0.176	0.824
C17 Malignant neoplasm of small intestine	0.823	0.177	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.814	0.186	0.000
E11.4 With neurological complications	0.000	0.188	0.812
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.192	0.808
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.202	0.798
C71.5 Cerebral ventricle	0.795	0.205	0.000
C16.9 Stomach, unspecified	0.795	0.205	0.000
D00-D09 In situ neoplasms	0.793	0.207	0.000
E11.8 With unspecified complications	0.000	0.214	0.786
I72.9 Aneurysm of unspecified site	0.000	0.217	0.783
I72.2 Aneurysm of renal artery	0.000	0.226	0.774
Z95.0 Presence of cardiac pacemaker	0.000	0.227	0.773
I62 Other nontraumatic intracranial haemorrhage	0.000	0.227	0.773
C44.4 Skin of scalp and neck	0.769	0.231	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.231	0.769
C02 Malignant neoplasm of other and unspecified parts of tongue	0.768	0.232	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.233	0.767
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.235	0.765
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.764	0.236	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.763	0.237	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.238	0.762
C21.0 Anus, unspecified	0.756	0.244	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.247	0.753
C16.5 Lesser curvature of stomach, unspecified	0.751	0.249	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.250	0.750
I72.4 Aneurysm of artery of lower extremity	0.000	0.258	0.742
E11.0 With coma	0.000	0.258	0.742
C23 Malignant neoplasm of gallbladder	0.736	0.264	0.000
D05 Carcinoma in situ of breast	0.736	0.264	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.735	0.265	0.000
E11.6 With other specified complications	0.000	0.268	0.732
C15.0 Cervical part of oesophagus	0.726	0.274	0.000
C16.8 Overlapping lesion of stomach	0.724	0.276	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.276	0.724
I25.6 Silent myocardial ischaemia	0.000	0.277	0.723
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.278	0.722
I72.8 Aneurysm of other specified arteries	0.000	0.279	0.721
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.280	0.720
C71.6 Cerebellum	0.717	0.283	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
C08 Malignant neoplasm of other and unspecified major salivary glands	0.717	0.283	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.283	0.717
I77.5 Necrosis of artery	0.000	0.286	0.714
I77.4 Coeliac artery compression syndrome	0.000	0.286	0.714
I77.3 Arterial fibromuscular dysplasia	0.000	0.286	0.714
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.292	0.708
C20 Malignant neoplasm of rectum	0.704	0.296	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.702	0.298	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.299	0.701
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.299	0.701
I72.1 Aneurysm of artery of upper extremity	0.000	0.299	0.701
C03 Malignant neoplasm of gum	0.700	0.300	0.000
C44.8 Overlapping lesion of skin	0.698	0.302	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.303	0.697
C69 Malignant neoplasm of eye and adnexa	0.696	0.304	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.305	0.695
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.695	0.305	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.693	0.307	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.307	0.693
C15.8 Overlapping lesion of oesophagus	0.690	0.310	0.000
C15.2 Abdominal part of oesophagus	0.690	0.310	0.000
C15.1 Thoracic part of oesophagus	0.690	0.310	0.000
C16.6 Greater curvature of stomach, unspecified	0.689	0.311	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.312	0.688
H40.3 Glaucoma secondary to eye trauma	0.000	0.314	0.686
D04 Carcinoma in situ of skin	0.686	0.314	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.315	0.685
C15.3 Upper third of oesophagus	0.684	0.316	0.000
C00 Malignant neoplasm of lip	0.684	0.316	0.000
C02.9 Tongue, unspecified	0.684	0.316	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.000	0.319	0.681
C44.2 Skin of ear and external auricular canal	0.676	0.324	0.000
C17.0 Duodenum	0.676	0.324	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.324	0.676
D05.7 Other carcinoma in situ of breast	0.673	0.327	0.000
I67.2 Cerebral atherosclerosis	0.000	0.328	0.672
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.330	0.670
Z82.3 Family history of stroke	0.000	0.333	0.667
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.665	0.335	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.335	0.665
I70.9 Generalised and unspecified atherosclerosis	0.000	0.336	0.663
C16.1 Fundus of stomach	0.663	0.337	0.000
C44.6 Skin of upper limb, including shoulder	0.663	0.337	0.000
C07 Malignant neoplasm of parotid gland	0.660	0.340	0.000
D04.3 Skin of other and unspecified parts of face	0.658	0.342	0.000
E11.7 With multiple complications	0.000	0.342	0.657
C71.7 Brain stem	0.657	0.342	0.000
C71.4 Occipital lobe	0.656	0.343	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.344	0.656
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.349	0.651
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.352	0.647
I73.8 Other specified peripheral vascular diseases	0.000	0.353	0.647
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.353	0.647
I67.5 Moyamoya disease	0.000	0.353	0.647
I67.4 Hypertensive encephalopathy	0.000	0.353	0.647
I67.3 Progressive vascular leukoencephalopathy	0.000	0.353	0.647
I23 Certain current complications following acute myocardial infarction	0.000	0.356	0.643
I00-I02 Acute rheumatic fever	0.000	0.358	0.642
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.358	0.642
C14.0 Pharynx, unspecified	0.641	0.359	0.000
H40.4 Glaucoma secondary to eye inflammation	0.000	0.360	0.640
C17.2 Ileum	0.639	0.361	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.361	0.639
C17.9 Small intestine, unspecified	0.638	0.362	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.365	0.635
E10-E14 Diabetes mellitus	0.000	0.367	0.633
C11 Malignant neoplasm of nasopharynx	0.631	0.369	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.371	0.628
I24.1 Dressler's syndrome	0.000	0.372	0.628
C21.2 Cloacogenic zone	0.623	0.377	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.622	0.378	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.378	0.621
C24.0 Extrahepatic bile duct	0.620	0.380	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.382	0.618
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.383	0.617
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.613	0.387	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.389	0.611
C10 Malignant neoplasm of oropharynx	0.611	0.389	0.000
D02.0 Larynx	0.610	0.390	0.000
C13 Malignant neoplasm of hypopharynx	0.607	0.393	0.000
C16.4 Pylorus	0.606	0.393	0.000
I79.1 Aortitis in diseases classified elsewhere	0.000	0.396	0.604
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.396	0.604
C02.4 Lingual tonsil	0.603	0.397	0.000
D04.2 Skin of ear and external auricular canal	0.603	0.397	0.000
D09 Carcinoma in situ of other and unspecified sites	0.600	0.400	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.598	0.402	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.403	0.597
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.406	0.594
I65.1 Occlusion and stenosis of basilar artery	0.000	0.408	0.592
C08.9 Major salivary gland, unspecified	0.590	0.410	0.000
C17.8 Overlapping lesion of small intestine	0.590	0.410	0.000
C17.3 Meckel's diverticulum	0.590	0.410	0.000
C16.2 Body of stomach	0.589	0.411	0.000
C04 Malignant neoplasm of floor of mouth	0.588	0.412	0.000
C01 Malignant neoplasm of base of tongue	0.588	0.412	0.000
C70 Malignant neoplasm of meninges	0.587	0.413	0.000
C02.2 Ventral surface of tongue	0.587	0.413	0.000
C03.9 Gum, unspecified	0.586	0.414	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.425	0.575
C05 Malignant neoplasm of palate	0.573	0.427	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.570	0.430	0.000
C17.1 Jejunum	0.569	0.431	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.434	0.565
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.437	0.563
D04.0 Skin of lip	0.560	0.440	0.000
C24.9 Biliary tract, unspecified	0.559	0.441	0.000
D02.2 Bronchus and lung	0.559	0.441	0.000
C69.9 Eye, unspecified	0.551	0.449	0.000
C02.8 Overlapping lesion of tongue	0.550	0.449	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.550	0.449	0.000
C02.0 Dorsal surface of tongue	0.550	0.449	0.000
I61 Intracerebral haemorrhage	0.000	0.450	0.550
C24.8 Overlapping lesion of biliary tract	0.548	0.452	0.000
C08.0 Submandibular gland	0.546	0.454	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.457	0.543
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.458	0.542
E11.2 With renal complications	0.000	0.459	0.541
C24.1 Ampulla of Vater	0.541	0.459	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.460	0.540
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.460	0.540
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.460	0.540
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.540	0.460	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.462	0.538
C69.2 Retina	0.537	0.463	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.464	0.536
C00.1 External lower lip	0.531	0.469	0.000
C21.1 Anal canal	0.529	0.471	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.529	0.471	0.000
C00.0 External upper lip	0.529	0.471	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.527	0.473	0.000
C14.2 Waldeyer's ring	0.527	0.473	0.000
I77.2 Rupture of artery	0.000	0.474	0.525
C31 Malignant neoplasm of accessory sinuses	0.524	0.476	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.521	0.479	0.000
E14 Unspecified diabetes mellitus	0.000	0.482	0.518
C03.0 Upper gum	0.517	0.483	0.000
C08.8 Overlapping lesion of major salivary glands	0.514	0.486	0.000
C08.1 Sublingual gland	0.514	0.486	0.000
D04.4 Skin of scalp and neck	0.513	0.487	0.000
D04.9 Skin, unspecified	0.512	0.488	0.000
C69.6 Orbit	0.510	0.490	0.000
C69.0 Conjunctiva	0.504	0.496	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.496	0.504
D02.4 Respiratory system, unspecified	0.503	0.497	0.000
D02.3 Other parts of respiratory system	0.503	0.497	0.000
D02.1 Trachea	0.503	0.497	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.502	0.497	0.000
D01.2 Rectum	0.502	0.498	0.000
D09.0 Bladder	0.502	0.498	0.000
C30.0 Nasal cavity	0.502	0.498	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.499	0.501
C37 Malignant neoplasm of thymus	0.500	0.499	0.000
C69.8 Overlapping lesion of eye and adnexa	0.499	0.501	0.000
C69.5 Lachrymal gland and duct	0.499	0.501	0.000
C69.4 Ciliary body	0.499	0.501	0.000
C69.1 Cornea	0.499	0.501	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.498	0.501	0.000
C72.9 Central nervous system, unspecified	0.498	0.502	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.498	0.502	0.000
C72.5 Other and unspecified cranial nerves	0.498	0.502	0.000
C72.4 Acoustic nerve	0.498	0.502	0.000
C72.3 Optic nerve	0.498	0.502	0.000
C72.2 Olfactory nerve	0.498	0.502	0.000
C72.1 Cauda equina	0.498	0.502	0.000
C72.0 Spinal cord	0.497	0.503	0.000
I70.0 Atherosclerosis of aorta	0.000	0.504	0.495
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.506	0.493
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.508	0.492
D04.8 Skin of other sites	0.492	0.508	0.000
C00.8 Overlapping lesion of lip	0.490	0.510	0.000
C00.6 Commissure of lip	0.490	0.510	0.000
C00.5 Lip, unspecified, inner aspect	0.490	0.510	0.000
C00.4 Lower lip, inner aspect	0.490	0.510	0.000
C00.3 Upper lip, inner aspect	0.490	0.510	0.000
C00.2 External lip, unspecified	0.490	0.510	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.510	0.490
I67.1 Cerebral aneurysm, nonruptured	0.000	0.515	0.485
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.515	0.484
E10.3 With ophthalmic complications	0.000	0.516	0.484
C02.1 Border of tongue	0.482	0.518	0.000
C00.9 Lip, unspecified	0.478	0.522	0.000
C03.1 Lower gum	0.478	0.522	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.522	0.478
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.477	0.523	0.000
C33 Malignant neoplasm of trachea	0.477	0.523	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.524	0.476
E10.4 With neurological complications	0.000	0.524	0.476
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.475	0.525	0.000
C12 Malignant neoplasm of pyriform sinus	0.475	0.525	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.525	0.475
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.472	0.528	0.000
E10.5 With peripheral circulatory complications	0.000	0.528	0.472
Z82.1 Family history of blindness and visual loss	0.000	0.528	0.472
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.529	0.471
C16.3 Pyloric antrum	0.468	0.531	0.000
C48.0 Retroperitoneum	0.466	0.534	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.464	0.536	0.000
E10.9 Without complications	0.000	0.536	0.464
C11.9 Nasopharynx, unspecified	0.464	0.536	0.000
E14.3 With ophthalmic complications	0.000	0.537	0.463
D01.0 Colon	0.462	0.538	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.538	0.461
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.538	0.461
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.538	0.461
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.461
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.538	0.461
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.538	0.461
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.461
I02 Rheumatic chorea	0.000	0.539	0.460
I01 Rheumatic fever with heart involvement	0.000	0.539	0.460
C13.0 Postcricoid region	0.459	0.541	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.545	0.455
E12 Malnutrition-related diabetes mellitus	0.000	0.546	0.454
D04.1 Skin of eyelid, including canthus	0.453	0.547	0.000
C11.8 Overlapping lesion of nasopharynx	0.453	0.547	0.000
C11.3 Anterior wall of nasopharynx	0.453	0.547	0.000
C11.2 Lateral wall of nasopharynx	0.453	0.547	0.000
C11.1 Posterior wall of nasopharynx	0.453	0.547	0.000
C11.0 Superior wall of nasopharynx	0.453	0.547	0.000
C06.0 Cheek mucosa	0.452	0.548	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.549	0.451
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.549	0.451
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.549	0.451
D06 Carcinoma in situ of cervix uteri	0.450	0.549	0.000
D09.9 Carcinoma in situ, unspecified	0.447	0.553	0.000
E10.8 With unspecified complications	0.000	0.554	0.446
D01.9 Digestive organ, unspecified	0.446	0.554	0.000
D01.7 Other specified digestive organs	0.446	0.554	0.000
D01.5 Liver, gallbladder and bile ducts	0.446	0.554	0.000
D01.4 Other and unspecified parts of intestine	0.446	0.554	0.000
D01.1 Rectosigmoid junction	0.446	0.554	0.000
C09 Malignant neoplasm of tonsil	0.441	0.559	0.000
E14.6 With other specified complications	0.000	0.559	0.441
C46 Kaposi's sarcoma	0.439	0.560	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.439	0.561	0.000
C10.8 Overlapping lesion of oropharynx	0.438	0.562	0.000
C10.4 Branchial cleft	0.438	0.562	0.000
C10.3 Posterior wall of oropharynx	0.438	0.562	0.000
C10.2 Lateral wall of oropharynx	0.438	0.562	0.000
C10.1 Anterior surface of epiglottis	0.438	0.562	0.000
C10.0 Vallecula	0.438	0.562	0.000
C13.8 Overlapping lesion of hypopharynx	0.435	0.564	0.000
C13.2 Posterior wall of hypopharynx	0.435	0.564	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.435	0.564	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.566	0.434
D09.3 Thyroid and other endocrine glands	0.430	0.570	0.000
D09.2 Eye	0.430	0.570	0.000
C10.9 Oropharynx, unspecified	0.429	0.571	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.429	0.571	0.000
C06.1 Vestibule of mouth	0.429	0.571	0.000
D05.0 Lobular carcinoma in situ	0.429	0.571	0.000
C15.4 Middle third of oesophagus	0.428	0.571	0.000
C05.9 Palate, unspecified	0.428	0.572	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.574	0.426
D09.7 Carcinoma in situ of other specified sites	0.425	0.574	0.000
Z82.2 Family history of deafness and hearing loss	0.000	0.575	0.425
D01.3 Anus and anal canal	0.423	0.577	0.000
C31.0 Maxillary sinus	0.422	0.578	0.000
C48.2 Peritoneum, unspecified	0.422	0.578	0.000
C04.8 Overlapping lesion of floor of mouth	0.422	0.578	0.000
C04.1 Lateral floor of mouth	0.422	0.578	0.000
C70.9 Meninges, unspecified	0.421	0.579	0.000
C70.1 Spinal meninges	0.421	0.579	0.000
H40-H42 Glaucoma	0.000	0.582	0.418
C06.2 Retromolar area	0.415	0.584	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.414	0.586	0.000
C04.0 Anterior floor of mouth	0.411	0.588	0.000
C05.8 Overlapping lesion of palate	0.411	0.589	0.000
C05.2 Uvula	0.411	0.589	0.000
C30.1 Middle ear	0.409	0.591	0.000
C32 Malignant neoplasm of larynx	0.408	0.592	0.000
C50-C50 Malignant neoplasm of breast	0.407	0.593	0.000
C38.4 Pleura	0.406	0.594	0.000
I00 Rheumatic fever without mention of heart involvement	0.000	0.597	0.403
I68.0 Cerebral amyloid angiopathy	0.000	0.597	0.402
E10.1 With ketoacidosis	0.000	0.598	0.401
C44.9 Malignant neoplasm of skin, unspecified	0.401	0.599	0.000
C04.9 Floor of mouth, unspecified	0.400	0.599	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.600	0.400
C48.1 Specified parts of peritoneum	0.399	0.601	0.000
E14.4 With neurological complications	0.000	0.602	0.398
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.398	0.602	0.000
C41.1 Mandible	0.397	0.602	0.000
C13.9 Hypopharynx, unspecified	0.393	0.606	0.000
C06.9 Mouth, unspecified	0.393	0.607	0.000
C41.9 Bone and articular cartilage, unspecified	0.392	0.607	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.608	0.392
C60-C63 Malignant neoplasms of male genital organs	0.391	0.609	0.000
E10.7 With multiple complications	0.000	0.609	0.391
E10.0 With coma	0.000	0.609	0.390
C38.3 Mediastinum, part unspecified	0.389	0.611	0.000
E10.6 With other specified complications	0.000	0.611	0.389
C05.1 Soft palate	0.388	0.612	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.612	0.388
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.387	0.613	0.000
E14.2 Withrenal complications	0.000	0.615	0.385
Z95.2 Presence of prosthetic heart valve	0.000	0.616	0.384
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.619	0.380
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.620	0.380
C41.8 Overlapping lesion of bone and articular cartilage	0.379	0.620	0.000
C41.3 Ribs, sternum and clavicle	0.379	0.620	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.623	0.377
C31.9 Accessory sinus, unspecified	0.375	0.624	0.000
C31.8 Overlapping lesion of accessory sinuses	0.375	0.624	0.000
C31.3 Sphenoidal sinus	0.375	0.624	0.000
C31.2 Frontal sinus	0.375	0.624	0.000
C31.1 Ethmoidal sinus	0.375	0.624	0.000
C64-C68 Malignant neoplasms of urinary tract	0.375	0.625	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.374	0.626	0.000
C38.2 Posterior mediastinum	0.374	0.626	0.000
C38.1 Anterior mediastinum	0.374	0.626	0.000
C38.0 Heart	0.374	0.626	0.000
C47.1 Peripheral nerves of upper limb, including shoulder	0.372	0.628	0.000
E14.7 With multiple complications	0.000	0.628	0.372
E14.0 With coma	0.000	0.628	0.372
E14.1 With ketoacidosis	0.000	0.629	0.371
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.629	0.371
C05.0 Hard palate	0.367	0.633	0.000
C41.2 Vertebral column	0.364	0.636	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.362	0.637	0.001
I71 Aortic aneurysm and dissection	0.000	0.638	0.362
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.638	0.362
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)	0.357	0.642	0.000
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)	0.357	0.642	0.000
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)	0.357	0.642	0.000
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)	0.357	0.642	0.000
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)	0.357	0.642	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.644	0.355
C41.0 Bones of skull and face	0.354	0.646	0.000
E14.8 With unspecified complications	0.000	0.648	0.352
C39.9 Ill-defined sites within the respiratory system	0.342	0.658	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.342	0.658	0.000
C39.0 Upper respiratory tract, part unspecified	0.342	0.658	0.000
C40.9 Bone and articular cartilage of limb, unspecified	0.341	0.659	0.000
C40.8 Overlapping lesion of bone and articular cartilage of limbs	0.341	0.659	0.000
C40.3 Short bones of lower limb	0.341	0.659	0.000
C40.1 Short bones of upper limb	0.341	0.659	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.660	0.340
D09.1 Other and unspecified urinary organs	0.339	0.661	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.339	0.661	0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.339	0.661	0.000
C47.6 Peripheral nerves of trunk, unspecified	0.339	0.661	0.000
C47.5 Peripheral nerves of pelvis	0.339	0.661	0.000
C47.4 Peripheral nerves of abdomen	0.339	0.661	0.000
C47.3 Peripheral nerves of thorax	0.339	0.661	0.000
C47.2 Peripheral nerves of lower limb, including hip	0.339	0.661	0.000
C47.0 Peripheral nerves of head, face and neck	0.339	0.661	0.000
C69.3 Choroid	0.338	0.662	0.000
E10.2 With renal complications	0.000	0.662	0.338
D06.0 Endocervix	0.337	0.663	0.000
C26.8 Overlapping lesion of digestive system	0.332	0.667	0.000
C26.1 Spleen	0.332	0.667	0.000
D04.6 Skin of upper limb, including shoulder	0.332	0.668	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.331	0.669	0.000
C40.0 Scapula and long bones of upper limb	0.331	0.669	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.670	0.330
I01.8 Other acute rheumatic heart disease	0.000	0.670	0.330
I01.2 Acute rheumatic myocarditis	0.000	0.670	0.330
I01.1 Acute rheumatic endocarditis	0.000	0.670	0.330
I01.0 Acute rheumatic pericarditis	0.000	0.670	0.330
I02.9 Rheumatic chorea without heart involvement	0.000	0.670	0.330
I02.0 Rheumatic chorea with heart involvement	0.000	0.670	0.330
C40.2 Long bones of lower limb	0.329	0.671	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.673	0.327
E12.9 Without complications	0.000	0.674	0.326
E12.8 With unspecified complications	0.000	0.674	0.326
E12.7 With multiple complications	0.000	0.674	0.326

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations