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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56536369
log Bayes Factor = 52.4476
Chromosome 6   position 32,726,788  (GRCh37) Explore rs56536369 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M20-M25 Other joint disorders
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.003 0.997
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.004 0.996
H04 Disorders of lachrymal system
0.000 0.005 0.995
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.005 0.994
E10.1 With ketoacidosis
0.000 0.006 0.994
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
N48 Other disorders of penis
0.991 0.009 0.000
H02 Other disorders of eyelid
0.000 0.009 0.991
J20-J22 Other acute lower respiratory infections
0.000 0.011 0.989
N48.6 Balanitis xerotica obliterans
0.988 0.012 0.000
J22 Unspecified acute lower respiratory infection
0.000 0.016 0.984
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.016 0.984
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.016 0.984
N40-N51 Diseases of male genital organs
0.982 0.018 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.979 0.021 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.024 0.976
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.026 0.974
H02.1 Ectropion of eyelid
0.000 0.026 0.974
E20-E35 Disorders of other endocrine glands
0.000 0.026 0.974
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.029 0.971
L20-L30 Dermatitis and eczema
0.000 0.032 0.968
M35.0 Sicca syndrome [Sjogren]
0.000 0.033 0.967
E27 Other disorders of adrenal gland
0.000 0.042 0.958
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.043 0.957
J80 Adult respiratory distress syndrome
0.000 0.043 0.957
Chapter V Mental and behavioural disorders
0.000 0.047 0.953
H02.0 Entropion and trichiasis of eyelid
0.000 0.051 0.949
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.052 0.948
F30-F39 Mood [affective] disorders
0.000 0.057 0.943
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.057 0.943
Chapter I Certain infectious and parasitic diseases
0.000 0.062 0.938
E27.1 Primary adrenocortical insufficiency
0.000 0.066 0.934
N48.0 Leukoplakia of penis
0.934 0.066 0.000
D68 Other coagulation defects
0.000 0.070 0.930
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.071 0.929
N48.8 Other specified disorders of penis
0.928 0.072 0.000
N45 Orchitis and epididymitis
0.926 0.074 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.076 0.924
B35-B49 Mycoses
0.000 0.080 0.920
M34 Systemic sclerosis
0.000 0.081 0.919
B37 Candidiasis
0.000 0.082 0.918
B37.8 Candidiasis of other sites
0.000 0.084 0.916
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.085 0.915
H04.2 Epiphora
0.000 0.086 0.914
F31 Bipolar affective disorder
0.000 0.093 0.907
C44 Other malignant neoplasms of skin
0.000 0.095 0.905
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.099 0.901
C44.3 Skin of other and unspecified parts of face
0.000 0.102 0.898
E10.5 With peripheral circulatory complications
0.000 0.105 0.895
J84 Other interstitial pulmonary diseases
0.000 0.105 0.895
F32 Depressive episode
0.000 0.106 0.894
M31 Other necrotising vasculopathies
0.000 0.106 0.894
D50-D53 Nutritional anaemias
0.000 0.106 0.894
C44.7 Skin of lower limb, including hip
0.000 0.109 0.891
E70-E90 Metabolic disorders
0.000 0.109 0.891
J00-J06 Acute upper respiratory infections
0.000 0.110 0.890
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.890 0.110 0.000
L81 Other disorders of pigmentation
0.000 0.112 0.888
E11 Non-insulin-dependent diabetes mellitus
0.000 0.113 0.887
H05 Disorders of orbit
0.000 0.116 0.884
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.117 0.883
M06.0 Seronegative rheumatoid arthritis
0.000 0.119 0.881
E11.3 With ophthalmic complications
0.000 0.122 0.878
L29 Pruritus
0.000 0.124 0.876
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.129 0.871
J95-J99 Other diseases of the respiratory system
0.000 0.131 0.869
E28 Ovarian dysfunction
0.000 0.132 0.868
E06 Thyroiditis
0.000 0.133 0.867
E10.2 With renal complications
0.000 0.134 0.866
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.135 0.865
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.135 0.865
J00 Acute nasopharyngitis [common cold]
0.000 0.135 0.865
B37.0 Candidal stomatitis
0.000 0.136 0.864
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.141 0.859
L81.4 Other melanin hyperpigmentation
0.000 0.142 0.858
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.144 0.856
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.146 0.854
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.147 0.853
L30 Other dermatitis
0.000 0.147 0.853
N48.9 Disorder of penis, unspecified
0.849 0.151 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.153 0.847
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.155 0.845
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.155 0.845
E10.4 With neurological complications
0.000 0.156 0.844
C44.0 Skin of lip
0.000 0.158 0.842
N48.4 Impotence of organic origin
0.841 0.159 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.160 0.840
M60-M63 Disorders of muscles
0.000 0.161 0.839
L27 Dermatitis due to substances taken internally
0.000 0.161 0.839
M34.9 Systemic sclerosis, unspecified
0.000 0.164 0.836
H04.8 Other disorders of lachrymal system
0.000 0.166 0.834
F32.1 Moderate depressive episode
0.000 0.168 0.832
M06.3 Rheumatoid nodule
0.000 0.169 0.831
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.831 0.169 0.000
D68.5 Primary Thrombophilia
0.000 0.171 0.829
D68.8 Other specified coagulation defects
0.000 0.174 0.826
C44.6 Skin of upper limb, including shoulder
0.000 0.176 0.824
C44.1 Skin of eyelid, including canthus
0.000 0.177 0.823
L57.0 Actinic keratosis
0.000 0.178 0.822
H53-H54 Visual disturbances and blindness
0.000 0.180 0.820
D68.0 Von Willebrand's disease
0.000 0.181 0.819
A63.0 Anogenital (venereal) warts
0.000 0.181 0.819
E27.8 Other specified disorders of adrenal gland
0.000 0.187 0.813
M31.3 Wegener's granulomatosis
0.000 0.187 0.813
L98.0 Pyogenic granuloma
0.000 0.188 0.812
D68.9 Coagulation defect, unspecified
0.000 0.190 0.810
E04 Other non-toxic goitre
0.000 0.193 0.807
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.200 0.800
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.200 0.800
D50 Iron deficiency anaemia
0.000 0.202 0.798
L29.0 Pruritus ani
0.000 0.202 0.798
L93 Lupus erythematosus
0.000 0.204 0.796
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.208 0.791
L83 Acanthosis nigricans
0.000 0.209 0.791
L08 Other local infections of skin and subcutaneous tissue
0.000 0.210 0.790
H55-H59 Other disorders of eye and adnexa
0.000 0.213 0.787
L85 Other epidermal thickening
0.000 0.217 0.783
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.218 0.782
E20 Hypoparathyroidism
0.000 0.219 0.781
F31.9 Bipolar affective disorder, unspecified
0.000 0.219 0.781
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.220 0.780
E89.0 Postprocedural hypothyroidism
0.000 0.220 0.780
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.222 0.778
F30 Manic episode
0.000 0.224 0.776
N48.5 Ulcer of penis
0.775 0.225 0.000
E06.3 Autoimmune thyroiditis
0.000 0.225 0.775
D60-D64 Aplastic and other anaemias
0.000 0.227 0.773
E10.8 With unspecified complications
0.000 0.228 0.772
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.228 0.772
H02.4 Ptosis of eyelid
0.000 0.230 0.770
N44 Torsion of testis
0.769 0.231 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.231 0.769
H05.0 Acute inflammation of orbit
0.000 0.233 0.767
F80-F89 Disorders of psychological development
0.000 0.236 0.764
E29 Testicular dysfunction
0.000 0.236 0.764
E28.2 Polycystic ovarian syndrome
0.000 0.238 0.762
E11.1 With ketoacidosis
0.000 0.239 0.761
N41 Inflammatory diseases of prostate
0.759 0.241 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.243 0.757
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.244 0.756
M35.7 Hypermobility syndrome
0.000 0.245 0.755
J20 Acute bronchitis
0.000 0.246 0.754
C44.2 Skin of ear and external auricular canal
0.000 0.247 0.753
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.247 0.753
D50.8 Other iron deficiency anaemias
0.000 0.247 0.753
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.248 0.752
H04.4 Chronic inflammation of lachrymal passages
0.000 0.248 0.752
L94 Other localised connective tissue disorders
0.000 0.249 0.751
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.253 0.747
E27.9 Disorder of adrenal gland, unspecified
0.000 0.254 0.746
L30.9 Dermatitis, unspecified
0.000 0.255 0.745
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.255 0.745
E86 Volume depletion
0.000 0.255 0.745
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.257 0.743
H53 Visual disturbances
0.000 0.258 0.742
M34.1 CR(E)ST syndrome
0.000 0.258 0.741
L80 Vitiligo
0.000 0.262 0.738
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.262 0.738
D68.6 Other Thrombophilia
0.000 0.263 0.737
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.265 0.735
H02.6 Xanthelasma of eyelid
0.000 0.267 0.733
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.268 0.732
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.273 0.727
L20 Atopic dermatitis
0.000 0.274 0.726
M62 Other disorders of muscle
0.000 0.274 0.726
N50 Other disorders of male genital organs
0.726 0.274 0.000
M21 Other acquired deformities of limbs
0.000 0.274 0.725
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.275 0.725
H02.9 Disorder of eyelid, unspecified
0.000 0.275 0.725
D52 Folate deficiency anaemia
0.000 0.275 0.725
D61 Other aplastic anaemias
0.000 0.277 0.723
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.277 0.722
J81 Pulmonary oedema
0.000 0.278 0.722
F34 Persistent mood [affective] disorders
0.000 0.278 0.722
E07 Other disorders of thyroid
0.000 0.279 0.721
H05.2 Exophthalmic conditions
0.000 0.279 0.721
B25-B34 Other viral diseases
0.000 0.280 0.720
N49.2 Inflammatory disorders of scrotum
0.720 0.280 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.281 0.719
L30.8 Other specified dermatitis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
M35.1 Other overlap syndromes
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.284 0.716
M32 Systemic lupus erythematosus
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
J98 Other respiratory disorders
0.000 0.285 0.715
H04.9 Disorder of lachrymal system, unspecified
0.000 0.285 0.714
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.286 0.714
C44.4 Skin of scalp and neck
0.000 0.286 0.714
H04.6 Other changes in lachrymal passages
0.000 0.286 0.714
H04.0 Dacryoadenitis
0.000 0.286 0.714
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.286 0.713
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.713
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.286 0.713
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.286 0.713
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.286 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.286 0.713
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.286 0.713
E10.6 With other specified complications
0.000 0.289 0.711
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.289 0.711
N48.3 Priapism
0.711 0.289 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.289 0.711
H35 Other retinal disorders
0.000 0.290 0.710
M06.34 Rheumatoid nodule (Hand)
0.000 0.290 0.710
J21 Acute bronchiolitis
0.000 0.291 0.709
F39 Unspecified mood [affective] disorder
0.000 0.293 0.707
F20 Schizophrenia
0.000 0.296 0.704
N51 Disorders of male genital organs in diseases classified elsewhere
0.704 0.296 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.299 0.701
H53.9 Visual disturbance, unspecified
0.000 0.299 0.701
E73 Lactose intolerance
0.000 0.299 0.700
J01 Acute sinusitis
0.000 0.300 0.700
N48.2 Other inflammatory disorders of penis
0.699 0.301 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.302 0.698
E32 Diseases of thymus
0.000 0.302 0.698
E31 Polyglandular dysfunction
0.000 0.302 0.698
E30 Disorders of puberty, not elsewhere classified
0.000 0.302 0.698
D51 Vitamin B12 deficiency anaemia
0.000 0.302 0.698
E23 Hypofunction and other disorders of pituitary gland
0.000 0.304 0.696
B07 Viral warts
0.000 0.305 0.695
F22 Persistent delusional disorders
0.000 0.305 0.695
L25 Unspecified contact dermatitis
0.000 0.306 0.694
L24 Irritant contact dermatitis
0.000 0.306 0.694
L21 Seborrhoeic dermatitis
0.000 0.306 0.694
L26 Exfoliative dermatitis
0.000 0.306 0.694
L22 Diaper [napkin] dermatitis
0.000 0.306 0.694
E27.2 Addisonian crisis
0.000 0.306 0.694
E28.3 Primary ovarian failure
0.000 0.308 0.692
M06.4 Inflammatory polyarthropathy
0.000 0.310 0.690
E88 Other metabolic disorders
0.000 0.311 0.689
E04.2 Non-toxic multinodular goitre
0.000 0.311 0.689
D61.9 Aplastic anaemia, unspecified
0.000 0.313 0.687
E27.5 Adrenomedullary hyperfunction
0.000 0.313 0.687
E27.0 Other adrenocortical overactivity
0.000 0.313 0.687
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.314 0.686
L87 Transepidermal elimination disorders
0.000 0.314 0.686
L88 Pyoderma gangrenosum
0.000 0.314 0.686
L86 Keratoderma in diseases classified elsewhere
0.000 0.314 0.686
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.315 0.685
L82 Seborrhoeic keratosis
0.000 0.315 0.685
L29.9 Pruritus, unspecified
0.000 0.316 0.684
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.316 0.684
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.317 0.683
H01 Other inflammation of eyelid
0.000 0.318 0.682
H02.2 Lagophthalmos
0.000 0.318 0.682
E05.8 Other thyrotoxicosis
0.000 0.320 0.680
L93.0 Discoid lupus erythematosus
0.000 0.320 0.680
M21.0 Valgus deformity, not elsewhere classified
0.000 0.320 0.679
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.321 0.679
L58 Radiodermatitis
0.000 0.321 0.679
L55 Sunburn
0.000 0.321 0.679
H55 Nystagmus and other irregular eye movements
0.000 0.321 0.679
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.322 0.677
E11.2 With renal complications
0.000 0.323 0.677
F38 Other mood [affective] disorders
0.000 0.324 0.676
D67 Hereditary factor IX deficiency
0.000 0.324 0.676
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.324 0.676
E04.0 Non-toxic diffuse goitre
0.000 0.324 0.676
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.325 0.675
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.326 0.674
L23 Allergic contact dermatitis
0.000 0.327 0.673
F23 Acute and transient psychotic disorders
0.000 0.327 0.673
D69 Purpura and other haemorrhagic conditions
0.000 0.327 0.673
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.328 0.672
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.328 0.672
A75-A79 Rickettsioses
0.000 0.328 0.672
A70-A74 Other diseases caused by chlamydiae
0.000 0.328 0.672
A20-A28 Certain zoonotic bacterial diseases
0.000 0.328 0.672
H53.0 Amblyopia ex anopsia
0.000 0.329 0.671
E14 Unspecified diabetes mellitus
0.000 0.329 0.671
N48.1 Balanoposthitis
0.671 0.329 0.000
J04 Acute laryngitis and tracheitis
0.000 0.330 0.669
B65-B83 Helminthiases
0.000 0.331 0.669
E65-E68 Obesity and other hyperalimentation
0.000 0.333 0.667
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.333 0.667
D68.4 Acquired coagulation factor deficiency
0.000 0.333 0.666
D68.1 Hereditary factor XI deficiency
0.000 0.333 0.666
F70-F79 Mental retardation
0.000 0.333 0.666
H35.8 Other specified retinal disorders
0.000 0.334 0.666
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.334 0.666
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.334 0.666
L98.5 Mucinosis of skin
0.000 0.334 0.666
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.334 0.666
L98.1 Factitial dermatitis
0.000 0.334 0.666
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.334 0.666
M00-M03 Infectious arthropathies
0.000 0.335 0.664
L01 Impetigo
0.000 0.337 0.663
L00 Staphylococcal scalded skin syndrome
0.000 0.337 0.663
M62.8 Other specified disorders of muscle
0.000 0.337 0.663
E26 Hyperaldosteronism
0.000 0.338 0.662
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.339 0.661
B48 Other mycoses, not elsewhere classified
0.000 0.340 0.660
B47 Mycetoma
0.000 0.340 0.660
B46 Zygomycosis
0.000 0.340 0.660
B45 Cryptococcosis
0.000 0.340 0.660
B43 Chromomycosis and phaeomycotic abscess
0.000 0.340 0.660
B42 Sporotrichosis
0.000 0.340 0.660
B41 Paracoccidioidomycosis
0.000 0.340 0.660
B40 Blastomycosis
0.000 0.340 0.660
B39 Histoplasmosis
0.000 0.340 0.660
B38 Coccidioidomycosis
0.000 0.340 0.660
M34.8 Other forms of systemic sclerosis
0.000 0.341 0.659
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.341 0.659
M34.0 Progressive systemic sclerosis
0.000 0.341 0.659
A65-A69 Other spirochaetal diseases
0.000 0.341 0.659
E74 Other disorders of carbohydrate metabolism
0.000 0.341 0.658
L28 Lichen simplex chronicus and prurigo
0.000 0.342 0.658
B37.7 Candidal septicaemia
0.000 0.342 0.658
B37.6 Candidal endocarditis
0.000 0.342 0.658
B37.5 Candidal meningitis
0.000 0.342 0.658
B37.1 Pulmonary candidiasis
0.000 0.342 0.658
J84.8 Other specified interstitial pulmonary diseases
0.000 0.342 0.658
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.342 0.658
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.344 0.656
L57.5 Actinic granuloma
0.000 0.344 0.656
L57.3 Poikiloderma of Civatte
0.000 0.344 0.656
L57.2 Cutis rhomboidalis nuchae
0.000 0.344 0.656
L57.1 Actinic reticuloid
0.000 0.344 0.656
B37.2 Candidiasis of skin and nail
0.000 0.344 0.656
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.344 0.656
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.345 0.655
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.347 0.653
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.348 0.652
F31.8 Other bipolar affective disorders
0.000 0.350 0.650
F31.7 Bipolar affective disorder, currently in remission
0.000 0.350 0.650
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.350 0.650
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.350 0.650
L29.2 Pruritus vulvae
0.000 0.350 0.650
N46 Male infertility
0.649 0.350 0.000
C44.8 Overlapping lesion of skin
0.000 0.351 0.649
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.352 0.648
E22 Hyperfunction of pituitary gland
0.000 0.353 0.647
E03.8 Other specified hypothyroidism
0.000 0.354 0.646
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.354 0.646
M11 Other crystal arthropathies
0.000 0.354 0.645
J95.0 Tracheostomy malfunction
0.000 0.355 0.645
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.355 0.645
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.356 0.644
E20.9 Hypoparathyroidism, unspecified
0.000 0.356 0.643
F25 Schizoaffective disorders
0.000 0.357 0.643
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.643 0.357 0.000
B50-B64 Protozoal diseases
0.000 0.357 0.643
H06.2 Dysthyroid exophthalmos
0.000 0.358 0.642
J84.0 Alveolar and parietoalveolar conditions
0.000 0.358 0.641
M31.9 Necrotising vasculopathy, unspecified
0.000 0.359 0.641
M31.8 Other specified necrotising vasculopathies
0.000 0.359 0.641
M31.7 Microscopic polyangiitis
0.000 0.359 0.641
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.359 0.641
M31.2 Lethal midline granuloma
0.000 0.359 0.641
M31.1 Thrombotic microangiopathy
0.000 0.359 0.641
M31.0 Hypersensitivity angiitis
0.000 0.359 0.641
L57.4 Cutis laxa senilis
0.000 0.359 0.641
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.360 0.640
E84 Cystic fibrosis
0.000 0.361 0.639
E79 Disorders of purine and pyrimidine metabolism
0.000 0.361 0.639
E77 Disorders of glycoprotein metabolism
0.000 0.361 0.639
E76 Disorders of glycosaminoglycan metabolism
0.000 0.361 0.639
E72 Other disorders of amino-acid metabolism
0.000 0.361 0.639
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.361 0.639
E70 Disorders of aromatic amino-acid metabolism
0.000 0.361 0.639
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.361 0.639
E34 Other endocrine disorders
0.000 0.363 0.637
L81.7 Pigmented purpuric dermatosis
0.000 0.363 0.636
L81.6 Other disorders of diminished melanin formation
0.000 0.363 0.636
L81.5 Leukoderma, not elsewhere classified
0.000 0.363 0.636
L81.3 Cafe au lait spots
0.000 0.363 0.636
L81.2 Freckles
0.000 0.363 0.636
L81.1 Chloasma
0.000 0.363 0.636
L81.0 Postinflammatory hyperpigmentation
0.000 0.363 0.636
M30 Polyarteritis nodosa and related conditions
0.000 0.364 0.636
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.364 0.636
E11.7 With multiple complications
0.000 0.364 0.636
F30.0 Hypomania
0.000 0.364 0.636
M31.6 Other giant cell arteritis
0.000 0.365 0.635
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.366 0.634
H05.9 Disorder of orbit, unspecified
0.000 0.366 0.634
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.366 0.634
H05.4 Enophthalmos
0.000 0.366 0.634
H05.3 Deformity of orbit
0.000 0.366 0.634
H05.1 Chronic inflammatory disorders of orbit
0.000 0.366 0.634
N41.9 Inflammatory disease of prostate, unspecified
0.633 0.367 0.000
B35 Dermatophytosis
0.000 0.367 0.633
A59 Trichomoniasis
0.000 0.367 0.633
A56 Other sexually transmitted chlamydial diseases
0.000 0.367 0.633
A54 Gonococcal infection
0.000 0.367 0.633
A53 Other and unspecified syphilis
0.000 0.367 0.633
A52 Late syphilis
0.000 0.367 0.633
A51 Early syphilis
0.000 0.367 0.633
A50 Congenital syphilis
0.000 0.367 0.633
A64 Unspecified sexually transmitted disease
0.000 0.367 0.633
A58 Granuloma inguinale
0.000 0.367 0.633
A57 Chancroid
0.000 0.367 0.633
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.367 0.633
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.368 0.632
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.368 0.632
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.368 0.632
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.368 0.632
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.368 0.632
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.368 0.632
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.368 0.632
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.368 0.632
M14 Arthropathies in other diseases classified elsewhere
0.000 0.368 0.632
L29.3 Anogenital pruritus, unspecified
0.000 0.372 0.628
L29.1 Pruritus scroti
0.000 0.372 0.628
D68.2 Hereditary deficiency of other clotting factors
0.000 0.372 0.628
E04.9 Non-toxic goitre, unspecified
0.000 0.372 0.628
M33 Dermatopolymyositis
0.000 0.372 0.628
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.372 0.628
H35.4 Peripheral retinal degeneration
0.000 0.373 0.627
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.373 0.627
L10-L14 Bullous disorders
0.000 0.374 0.626
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.374 0.625
D55-D59 Haemolytic anaemias
0.000 0.375 0.625
E50-E64 Other nutritional deficiencies
0.000 0.375 0.625
H04.1 Other disorders of lachrymal gland
0.000 0.375 0.625
N42 Other disorders of prostate
0.624 0.376 0.000
J96 Respiratory failure, not elsewhere classified
0.000 0.377 0.623
J95.8 Other postprocedural respiratory disorders
0.000 0.377 0.623
M22 Disorders of patella
0.000 0.377 0.622
E28.9 Ovarian dysfunction, unspecified
0.000 0.378 0.622
E28.8 Other ovarian dysfunction
0.000 0.378 0.622
E28.1 Androgen excess
0.000 0.378 0.622
E28.0 Oestrogen excess
0.000 0.378 0.622
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.378 0.622
E06.5 Other chronic thyroiditis
0.000 0.378 0.622
E06.4 Drug-induced thyroiditis
0.000 0.378 0.622
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.378 0.622
E06.1 Subacute thyroiditis
0.000 0.378 0.622
E06.0 Acute thyroiditis
0.000 0.378 0.622
L81.8 Other specified disorders of pigmentation
0.000 0.379 0.621
L85.8 Other specified epidermal thickening
0.000 0.380 0.620
E87.7 Fluid overload
0.000 0.380 0.620
M86-M90 Other osteopathies
0.000 0.380 0.619
D62 Acute posthaemorrhagic anaemia
0.000 0.381 0.619
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.381 0.618
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.382 0.617
L04 Acute lymphadenitis
0.000 0.383 0.617

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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