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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs57139556
log Bayes Factor = 8.36685
Chromosome 6   position 150,998,511  (GRCh37) Explore rs57139556 on Ensembl!
Variant rs57139556 is part of Cluster X0011

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.108 0.892
I11 Hypertensive heart disease
0.000 0.220 0.780
I20-I25 Ischaemic heart diseases
0.000 0.247 0.753
I25 Chronic ischaemic heart disease
0.000 0.257 0.743
I24 Other acute ischaemic heart diseases
0.000 0.261 0.739
Chapter IX Diseases of the circulatory system
0.000 0.262 0.738
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.268 0.732
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.274 0.726
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.300 0.700
I21 Acute myocardial infarction
0.000 0.312 0.688
I25.1 Atherosclerotic heart disease
0.000 0.327 0.673
I12 Hypertensive renal disease
0.000 0.338 0.662
I13 Hypertensive heart and renal disease
0.000 0.360 0.639
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.364 0.636
I60-I69 Cerebrovascular diseases
0.000 0.376 0.624
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.398 0.602
I24.8 Other forms of acute ischaemic heart disease
0.000 0.402 0.598
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.419 0.581
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.420 0.580
I15 Secondary hypertension
0.000 0.422 0.577
I67 Other cerebrovascular diseases
0.000 0.430 0.570
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.441 0.559
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.455 0.545
I23 Certain current complications following acute myocardial infarction
0.000 0.460 0.540
I25.4 Coronary artery aneurysm
0.000 0.463 0.537
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.466 0.534
I25.6 Silent myocardial ischaemia
0.000 0.467 0.533
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.467 0.533
I00-I02 Acute rheumatic fever
0.000 0.471 0.529
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.473 0.527
I25.2 Old myocardial infarction
0.000 0.480 0.520
I67.8 Other specified cerebrovascular diseases
0.000 0.483 0.517
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.496 0.504
I12.9 Hypertensive renal disease without renal failure
0.000 0.505 0.494
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.507 0.493
I65.2 Occlusion and stenosis of carotid artery
0.000 0.512 0.488
I05-I09 Chronic rheumatic heart diseases
0.000 0.520 0.480
I12.0 Hypertensive renal disease with renal failure
0.000 0.523 0.477
I67.1 Cerebral aneurysm, nonruptured
0.000 0.531 0.469
I25.5 Ischaemic cardiomyopathy
0.000 0.540 0.460
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.541 0.458
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.541 0.458
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.541 0.458
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.541 0.458
I24.1 Dressler's syndrome
0.000 0.552 0.448
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.552 0.448
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.552 0.448
I67.9 Cerebrovascular disease, unspecified
0.000 0.558 0.442
I20 Angina pectoris
0.000 0.570 0.430
I22 Subsequent myocardial infarction
0.000 0.574 0.426
I67.2 Cerebral atherosclerosis
0.000 0.580 0.420
I15.9 Seconday hypertension, unspecified
0.000 0.586 0.414
I15.8 Other secondary hypertension
0.000 0.586 0.414
I15.2 Hypertension secondary to endocrine disorders
0.000 0.586 0.414
I15.0 Renovascular hypertension
0.000 0.586 0.414
I61 Intracerebral haemorrhage
0.000 0.587 0.413
I05 Rheumatic mitral valve diseases
0.000 0.589 0.411
I21.9 Acute myocardial infarction, unspecified
0.000 0.591 0.409
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.591 0.409
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.591 0.409
I67.5 Moyamoya disease
0.000 0.591 0.409
I67.4 Hypertensive encephalopathy
0.000 0.591 0.409
I67.3 Progressive vascular leukoencephalopathy
0.000 0.591 0.409
I63 Cerebral infarction
0.000 0.592 0.408
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.596 0.403
I20.0 Unstable angina
0.000 0.599 0.401
I62 Other nontraumatic intracranial haemorrhage
0.000 0.599 0.401
I21.4 Acute subendocardial myocardial infarction
0.000 0.608 0.392
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.608 0.392
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.609 0.391
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.609 0.391
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.609 0.391
I65.1 Occlusion and stenosis of basilar artery
0.000 0.609 0.391
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.609 0.391
I23.8 Other current complications following acute myocardial infarction
0.000 0.613 0.387
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.613 0.387
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.613 0.387
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.613 0.387
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.613 0.387
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.613 0.387
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.613 0.387
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.613 0.387
I02 Rheumatic chorea
0.000 0.620 0.379
I01 Rheumatic fever with heart involvement
0.000 0.620 0.379
I00 Rheumatic fever without mention of heart involvement
0.000 0.620 0.379
I15.1 Hypertension secondary to other renal disorders
0.000 0.648 0.352
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.649 0.350
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.653 0.346
I09 Other rheumatic heart diseases
0.000 0.656 0.344
I06 Rheumatic aortic valve diseases
0.000 0.656 0.344
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.658 0.342
I60 Subarachnoid haemorrhage
0.000 0.659 0.341
I05.9 Mitral valve disease, unspecified
0.000 0.660 0.340
I25.3 Aneurysm of heart
0.001 0.666 0.333
I05.0 Mitral stenosis
0.000 0.669 0.331
I07 Rheumatic tricuspid valve diseases
0.000 0.670 0.330
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.679 0.321
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.679 0.321
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.679 0.321
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.679 0.321
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.679 0.321
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.679 0.321
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.679 0.321
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.679 0.321
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.679 0.321
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.679 0.321
I68.0 Cerebral amyloid angiopathy
0.000 0.679 0.321
I05.2 Mitral stenosis with insufficiency
0.000 0.683 0.317
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.689 0.311
I22.8 Subsequent myocardial infarction of other sites
0.000 0.690 0.310
I63.8 Other cerebral infarction
0.000 0.694 0.306
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.702 0.298
I61.8 Other intracerebral haemorrhage
0.000 0.703 0.296
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.703 0.296
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.703 0.296
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.703 0.296
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.703 0.296
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.704 0.296
I05.8 Other mitral valve diseases
0.000 0.705 0.294
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.707 0.293
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.707 0.293
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.707 0.293
I28 Other diseases of pulmonary vessels
0.001 0.710 0.289
I27 Other pulmonary heart diseases
0.001 0.711 0.289
I62.1 Nontraumatic extradural haemorrhage
0.000 0.712 0.287
I63.9 Cerebral infarction, unspecified
0.000 0.714 0.286
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.721 0.279
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.726 0.274
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.728 0.272
I01.8 Other acute rheumatic heart disease
0.000 0.728 0.272
I01.2 Acute rheumatic myocarditis
0.000 0.728 0.272
I01.1 Acute rheumatic endocarditis
0.000 0.728 0.272
I01.0 Acute rheumatic pericarditis
0.000 0.728 0.272
I02.9 Rheumatic chorea without heart involvement
0.000 0.728 0.272
I02.0 Rheumatic chorea with heart involvement
0.000 0.728 0.272
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.728 0.272
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.729 0.271
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.734 0.266
I69 Sequelae of cerebrovascular disease
0.000 0.735 0.265
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.735 0.265
I05.1 Rheumatic mitral insufficiency
0.000 0.737 0.263
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.743 0.257
I20.1 Angina pectoris with documented spasm
0.000 0.746 0.254
I27.0 Primary pulmonary hypertension
0.000 0.747 0.253
I72 Other aneurysm
0.000 0.747 0.253
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.749 0.250
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.753 0.247
I06.8 Other rheumatic aortic valve diseases
0.000 0.753 0.247
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.753 0.247
I06.1 Rheumatic aortic insufficiency
0.000 0.753 0.247
I06.0 Rheumatic aortic stenosis
0.000 0.753 0.247
I09.9 Rheumatic heart disease, unspecified
0.000 0.753 0.247
I09.8 Other specified rheumatic heart diseases
0.000 0.753 0.247
I09.2 Chronic rheumatic pericarditis
0.000 0.753 0.247
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.753 0.247
I09.0 Rheumatic myocarditis
0.000 0.753 0.247
I99 Other and unspecified disorders of circulatory system
0.000 0.753 0.247
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.755 0.245
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.755 0.245
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.755 0.245
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.755 0.245
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.755 0.245
I95 Hypotension
0.000 0.759 0.241
I07.9 Tricuspid valve disease, unspecified
0.000 0.763 0.237
I07.8 Other tricuspid valve diseases
0.000 0.763 0.237
I07.2 Tricuspid stenosis with insufficiency
0.000 0.763 0.237
I07.0 Tricuspid stenosis
0.000 0.763 0.237
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.765 0.235
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.766 0.234
I70 Atherosclerosis
0.000 0.774 0.226
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.776 0.223
I72.4 Aneurysm of artery of lower extremity
0.000 0.777 0.223
I07.1 Tricuspid insufficiency
0.000 0.777 0.222
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.777 0.222
I95.1 Orthostatic hypotension
0.000 0.781 0.219
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.790 0.210
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.792 0.207
I28.8 Other specified diseases of pulmonary vessels
0.001 0.792 0.207
I28.1 Aneurysm of pulmonary artery
0.001 0.792 0.207
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.792 0.207
I27.8 Other specified pulmonary heart diseases
0.001 0.792 0.207
I27.1 Kyphoscoliotic heart disease
0.001 0.792 0.207
I97.1 Other functional disturbances following cardiac surgery
0.000 0.792 0.207
I72.0 Aneurysm of carotid artery
0.000 0.794 0.206
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.799 0.201
I78 Diseases of capillaries
0.000 0.801 0.199
I72.3 Aneurysm of iliac artery
0.000 0.805 0.195
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.805 0.194
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.806 0.194
I97.0 Postcardiotomy syndrome
0.000 0.806 0.194
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.809 0.190
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.810 0.190
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.810 0.190
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.810 0.190
I98.0 Cardiovascular syphilis
0.000 0.810 0.190
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.810 0.189
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.811 0.189
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.811 0.189
I72.8 Aneurysm of other specified arteries
0.000 0.817 0.183
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.818 0.181
I72.9 Aneurysm of unspecified site
0.000 0.819 0.181
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.819 0.181
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.819 0.181
I72.2 Aneurysm of renal artery
0.000 0.819 0.181
I72.1 Aneurysm of artery of upper extremity
0.000 0.819 0.181
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.822 0.178
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.824 0.175
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.827 0.173
I95.0 Idiopathic hypotension
0.000 0.827 0.173
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.829 0.171
I27.2 Other secondary pulmonary hypertension
0.000 0.831 0.169
I70.0 Atherosclerosis of aorta
0.000 0.832 0.168
I27.9 Pulmonary heart disease, unspecified
0.001 0.835 0.164
I26 Pulmonary embolism
0.003 0.835 0.161
I95.2 Hypotension due to drugs
0.000 0.837 0.162
I70.9 Generalised and unspecified atherosclerosis
0.000 0.838 0.162
I70.8 Atherosclerosis of other arteries
0.000 0.838 0.162
I70.1 Atherosclerosis of renal artery
0.000 0.838 0.162
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.838 0.162
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.841 0.158
I60.8 Other subarachnoid haemorrhage
0.001 0.846 0.153
I20.8 Other forms of angina pectoris
0.000 0.848 0.151
I08 Multiple valve diseases
0.000 0.849 0.150
I95.8 Other hypotension
0.000 0.852 0.147
I78.9 Disease of capillaries, unspecified
0.000 0.857 0.143
I78.8 Other diseases of capillaries
0.000 0.857 0.143
I20.9 Angina pectoris, unspecified
0.000 0.859 0.141
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.862 0.137
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.864 0.136
I79.1 Aortitis in diseases classified elsewhere
0.000 0.864 0.136
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.864 0.136
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.864 0.135
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.871 0.128
I77 Other disorders of arteries and arterioles
0.000 0.873 0.127
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.873 0.126
I78.1 Naevus, nonneoplastic
0.000 0.875 0.125
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.879 0.121
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.883 0.116
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.883 0.116
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.883 0.116
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.883 0.116
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.883 0.116
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.883 0.116
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.884 0.116
I74 Arterial embolism and thrombosis
0.000 0.885 0.115
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.003 0.886 0.112
I08.9 Multiple valve disease, unspecified
0.000 0.892 0.108
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.895 0.105
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.897 0.103
I77.8 Other specified disorders of arteries and arterioles
0.000 0.905 0.094
I77.5 Necrosis of artery
0.000 0.909 0.091
I77.4 Coeliac artery compression syndrome
0.000 0.909 0.091
I77.3 Arterial fibromuscular dysplasia
0.000 0.909 0.091
I77.0 Arteriovenous fistula, acquired
0.000 0.909 0.091
I73 Other peripheral vascular diseases
0.000 0.913 0.086
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.915 0.084
I08.0 Disorders of both mitral and aortic valves
0.000 0.916 0.084
I74.8 Embolism and thrombosis of other arteries
0.000 0.917 0.082
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.917 0.082
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.917 0.082
I77.2 Rupture of artery
0.000 0.920 0.080
I71 Aortic aneurysm and dissection
0.000 0.921 0.079
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.925 0.075
I30-I52 Other forms of heart disease
0.000 0.927 0.073
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.927 0.072
I74.5 Embolism and thrombosis of iliac artery
0.000 0.927 0.072
I08.8 Other multiple valve diseases
0.001 0.930 0.069
I42 Cardiomyopathy
0.000 0.933 0.067
I46 Cardiac arrest
0.000 0.935 0.065
I69.3 Sequelae of cerebral infarction
0.002 0.937 0.061
D47.1 Chronic myeloproliferative disease
0.063 0.937 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.937 0.062
I73.8 Other specified peripheral vascular diseases
0.000 0.938 0.062
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.938 0.062
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.062 0.938 0.000
I38 Endocarditis, valve unspecified
0.000 0.941 0.059
I42.9 Cardiomyopathy, unspecified
0.000 0.941 0.059
I46.0 Cardiac arrest with successful resuscitation
0.000 0.941 0.059
I49 Other cardiac arrhythmias
0.000 0.942 0.058
I33 Acute and subacute endocarditis
0.000 0.942 0.058
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.942 0.058
D47.3 Essential (haemorrhagic) thrombocythaemia
0.058 0.942 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.942 0.057
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.943 0.057
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.943 0.057
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.943 0.057
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.943 0.057
I77.6 Arteritis, unspecified
0.000 0.943 0.057
I45 Other conduction disorders
0.000 0.944 0.056
I77.1 Stricture of artery
0.000 0.944 0.056
I42.0 Dilated cardiomyopathy
0.000 0.945 0.055
D37-D48 Neoplasms of uncertain or unknown behaviour
0.054 0.946 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.947 0.053
I48 Atrial fibrillation and flutter
0.000 0.947 0.053
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.947 0.053
I41 Myocarditis in diseases classified elsewhere
0.000 0.947 0.053
I40 Acute myocarditis
0.000 0.947 0.053
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.947 0.053
I32 Pericarditis in diseases classified elsewhere
0.000 0.947 0.053
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.053 0.947 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.949 0.051
I49.1 Atrial premature depolarisation
0.000 0.949 0.051
I42.8 Other cardiomyopathies
0.000 0.949 0.051
D46 Myelodysplastic syndromes
0.050 0.949 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.950 0.050
I37 Pulmonary valve disorders
0.000 0.950 0.049
D37.4 Colon
0.049 0.951 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.952 0.048
I42.5 Other restrictive cardiomyopathy
0.000 0.952 0.048
I42.4 Endocardial fibroelastosis
0.000 0.952 0.048
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.952 0.048
I71.0 Dissection of aorta [any part]
0.000 0.952 0.048
D47.4 Osteomyelofibrosis
0.047 0.952 0.000
I33.0 Acute and subacute infective endocarditis
0.000 0.953 0.047
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.953 0.047
I35 Nonrheumatic aortic valve disorders
0.000 0.953 0.047
I49.0 Ventricular fibrillation and flutter
0.000 0.953 0.047
I46.1 Sudden cardiac death, so described
0.000 0.953 0.047
I46.9 Cardiac arrest, unspecified
0.000 0.953 0.047
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.954 0.046
I49.3 Ventricular premature depolarisation
0.000 0.954 0.046
I49.9 Cardiac arrhythmia, unspecified
0.000 0.954 0.046
I45.5 Other specified heart block
0.000 0.955 0.045
D37.5 Rectum
0.045 0.955 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.045 0.955 0.000
D47.2 Monoclonal gammopathy
0.045 0.955 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.044 0.955 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.044 0.955 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.044 0.955 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.044 0.955 0.000
I30 Acute pericarditis
0.000 0.956 0.044
I49.4 Other and unspecified premature depolarisation
0.000 0.956 0.044
D37.3 Appendix
0.043 0.957 0.000
D45 Polycythaemia vera
0.043 0.957 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.957 0.043
D46.7 Other myelodysplastic syndromes
0.043 0.957 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.043 0.957 0.000
I35.0 Aortic (valve) stenosis
0.000 0.958 0.042
I49.2 Junctional premature depolarisation
0.000 0.958 0.042
I33.9 Acute endocarditis, unspecified
0.000 0.958 0.042
I45.9 Conduction disorder, unspecified
0.000 0.958 0.042
I45.6 Preexcitation syndrome
0.000 0.958 0.041
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.959 0.041
D37.9 Digestive organ, unspecified
0.041 0.959 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.959 0.041
D37.1 Stomach
0.041 0.959 0.000
I45.4 Nonspecific intraventricular block
0.000 0.960 0.040
I45.3 Trifascicular block
0.000 0.960 0.040
I45.0 Right fascicular block
0.000 0.960 0.040
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.039 0.961 0.000
D37.2 Small intestine
0.038 0.962 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.962 0.038
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.962 0.038
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.962 0.038
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I40.9 Acute myocarditis, unspecified
0.000 0.962 0.038
I40.8 Other acute myocarditis
0.000 0.962 0.038
I40.1 Isolated myocarditis
0.000 0.962 0.038
I40.0 Infective myocarditis
0.000 0.962 0.038
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.962 0.038
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.962 0.038
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.962 0.038
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.962 0.038
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.962 0.038
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.962 0.038
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.962 0.038
I48.4 Atypical atrial flutter
0.000 0.962 0.038
I48.3 Typical atrial flutter
0.000 0.962 0.038
I48.2 Chronic atrial fibrillation
0.000 0.962 0.038
I48.1 Persistent atrial fibrillation
0.000 0.962 0.038
I48.0 Paroxysmal atrial fibrillation
0.000 0.962 0.038
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.962 0.038
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.962 0.038
I45.2 Bifascicular block
0.000 0.962 0.038
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.037 0.963 0.000
I45.8 Other specified conduction disorders
0.000 0.963 0.037
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.037 0.963 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.036 0.964 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.036 0.964 0.000
D46.4 Refractory anaemia, unspecified
0.036 0.964 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.036 0.964 0.000
D46.2 Refractory anaemia with excess of blasts
0.036 0.964 0.000
D46.1 Refractory anaemia with sideroblasts
0.036 0.964 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.036 0.964 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.964 0.036
I37.8 Other pulmonary valve disorders
0.000 0.964 0.036
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.964 0.036
I37.0 Pulmonary valve stenosis
0.000 0.964 0.036
D37.6 Liver, gallbladder and bile ducts
0.035 0.965 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.965 0.035
D44.0 Thyroid gland
0.035 0.965 0.000
D37.0 Lip, oral cavity and pharynx
0.035 0.965 0.000
I95.9 Hypotension, unspecified
0.000 0.966 0.034
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.034 0.966 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.034 0.966 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.034 0.966 0.000
I35.1 Aortic (valve) insufficiency
0.000 0.967 0.033
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.033 0.967 0.000
I37.1 Pulmonary valve insufficiency
0.000 0.967 0.032
I31 Other diseases of pericardium
0.000 0.968 0.032
I30.8 Other forms of acute pericarditis
0.000 0.968 0.032
I30.1 Infective pericarditis
0.000 0.968 0.032
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.968 0.032
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.969 0.031
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.969 0.031
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.969 0.031
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.969 0.031
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.969 0.031
D44.9 Endocrine gland, unspecified
0.031 0.969 0.000
D44.8 Pluriglandular involvement
0.031 0.969 0.000
D44.7 Aortic body and other paraganglia
0.031 0.969 0.000
D44.6 Carotid body
0.031 0.969 0.000
D44.5 Pineal gland
0.031 0.969 0.000
D44.4 Craniopharyngeal duct
0.031 0.969 0.000
D44.3 Pituitary gland
0.031 0.969 0.000
D44.2 Parathyroid gland
0.031 0.969 0.000
D44.1 Adrenal gland
0.031 0.969 0.000
D37.7 Other digestive organs
0.030 0.970 0.000
D41.4 Bladder
0.030 0.970 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.971 0.029
I73.0 Raynaud's syndrome
0.000 0.971 0.029
I34 Nonrheumatic mitral valve disorders
0.000 0.972 0.028
D42.9 Meninges, unspecified
0.028 0.972 0.000
D42.1 Spinal meninges
0.028 0.972 0.000
D42.0 Cerebral meninges
0.028 0.972 0.000
D48.0 Bone and articular cartilage
0.028 0.972 0.000
I51.4 Myocarditis, unspecified
0.000 0.972 0.028
I35.9 Aortic valve disorder, unspecified
0.000 0.972 0.027
I35.8 Other aortic valve disorders
0.000 0.973 0.027
D40.9 Male genital organ, unspecified
0.027 0.973 0.000
D40.7 Other male genital organs
0.027 0.973 0.000
D40.1 Testis
0.027 0.973 0.000
I49.5 Sick sinus syndrome
0.000 0.973 0.027
D41.9 Urinary organ, unspecified
0.026 0.973 0.000
D41.7 Other urinary organs
0.026 0.973 0.000
D41.3 Urethra
0.026 0.973 0.000
D41.2 Ureter
0.026 0.973 0.000
D41.1 Renal pelvis
0.026 0.973 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.974 0.026
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.974 0.026
I51.5 Myocardial degeneration
0.000 0.974 0.025
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.974 0.025
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.974 0.025
D40.0 Prostate
0.025 0.974 0.000
I51.7 Cardiomegaly
0.000 0.975 0.025
D48.7 Other specified sites
0.025 0.975 0.000
D39.9 Female genital organ, unspecified
0.024 0.975 0.000
D39.7 Other female genital organs
0.024 0.975 0.000
D39.2 Placenta
0.024 0.975 0.000
D39.0 Uterus
0.024 0.975 0.000
D38.6 Respiratory organ, unspecified
0.024 0.975 0.000
D38.5 Other respiratory organs
0.024 0.975 0.000
D38.4 Thymus
0.024 0.975 0.000
D38.3 Mediastinum
0.024 0.975 0.000
D38.2 Pleura
0.024 0.975 0.000
D38.0 Larynx
0.024 0.975 0.000
D43.9 Central nervous system, unspecified
0.024 0.976 0.000
D43.7 Other parts of central nervous system
0.024 0.976 0.000
D43.4 Spinal cord
0.024 0.976 0.000
D43.3 Cranial nerves
0.024 0.976 0.000
D43.1 Brain, infratentorial
0.024 0.976 0.000
D43.0 Brain, supratentorial
0.024 0.976 0.000
I49.8 Other specified cardiac arrhythmias
0.000 0.976 0.024
I47 Paroxysmal tachycardia
0.000 0.976 0.024
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.023 0.976 0.000
D48.4 Peritoneum
0.023 0.976 0.000
D48.3 Retroperitoneum
0.023 0.976 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.023 0.976 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.977 0.023
I30.9 Acute pericarditis, unspecified
0.000 0.977 0.023
I31.8 Other specified diseases of pericardium
0.000 0.977 0.023
I31.2 Haemopericardium, not elsewhere classified
0.000 0.977 0.023
I31.1 Chronic constrictive pericarditis
0.000 0.977 0.023
I31.0 Chronic adhesive pericarditis
0.000 0.977 0.023
I51.9 Heart disease, unspecified
0.000 0.977 0.023
D48.5 Skin
0.023 0.977 0.000
Y40 Systemic antibiotics
0.022 0.978 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.022 0.978 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.978 0.021
Y40.0 Penicillins
0.022 0.978 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.979 0.021
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.979 0.021
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.979 0.021
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.020 0.980 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.980 0.020
D39.1 Ovary
0.019 0.981 0.000
I31.9 Disease of pericardium, unspecified
0.000 0.981 0.019
D38.1 Trachea, bronchus and lung
0.019 0.981 0.000
D43.2 Brain, unspecified
0.019 0.981 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.019 0.981 0.000
D41.0 Kidney
0.019 0.981 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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