TreeWAS – Variant ID: rs5750250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C50.2 Upper-inner quadrant of breast	0.000	0.992	0.008
C50 Malignant neoplasm of breast	0.000	0.993	0.007
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.993	0.007
C50.3 Lower-inner quadrant of breast	0.000	0.994	0.006
C50.4 Upper-outer quadrant of breast	0.000	0.994	0.006
C50.0 Nipple and areola	0.000	0.994	0.006
C50.8 Overlapping lesion of breast	0.000	0.994	0.006
C50.5 Lower-outer quadrant of breast	0.000	0.994	0.006
C50.6 Axillary tail of breast	0.000	0.995	0.005
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.995	0.005
H02.8 Other specified disorders of eyelid	0.004	0.996	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
N64.5 Other signs and symptoms in breast	0.000	0.996	0.004
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.996	0.004
M19.94 Arthrosis, unspecified (Hand)	0.000	0.996	0.004
C50.1 Central portion of breast	0.000	0.996	0.004
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.996	0.004
Z53.9 Procedure not carried out, unspecified reason	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.997	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.997	0.003
R47.8 Other and unspecified speech disturbances	0.000	0.997	0.003
C50-C50 Malignant neoplasm of breast	0.000	0.997	0.003
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.997	0.003
M79.66 Pain in limb (Lower leg)	0.000	0.997	0.003
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
M19.0 Primary arthrosis of other joints	0.000	0.997	0.003
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
M19.9 Arthrosis, unspecified	0.000	0.997	0.003
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.997	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.997	0.002
O32.1 Maternal care for breech presentation	0.000	0.997	0.002
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.998	0.002
D37.5 Rectum	0.000	0.998	0.002
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
D37.4 Colon	0.000	0.998	0.002
Z90.1 Acquired absence of breast(s)	0.000	0.998	0.002
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.998	0.002
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
D37.2 Small intestine	0.000	0.998	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.998	0.002
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.002
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
M19 Other arthrosis	0.000	0.998	0.002
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
D37.6 Liver, gallbladder and bile ducts	0.000	0.998	0.002
M19.2 Other secondary arthrosis	0.000	0.998	0.002
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.998	0.002
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
D37.3 Appendix	0.000	0.998	0.002
D50.8 Other iron deficiency anaemias	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
C50.9 Breast, unspecified	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.000	0.998	0.002
D37.1 Stomach	0.000	0.998	0.002
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
M19.23 Other secondary arthrosis (Forearm)	0.000	0.998	0.002
M19.8 Other specified arthrosis	0.000	0.998	0.002
M19.29 Other secondary arthrosis (Site unspecified)	0.000	0.998	0.002
M19.28 Other secondary arthrosis (Other)	0.000	0.998	0.002
M19.26 Other secondary arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.000	0.998	0.002
M19.24 Other secondary arthrosis (Hand)	0.000	0.998	0.002
M19.22 Other secondary arthrosis (Upper arm)	0.000	0.998	0.002
M19.20 Other secondary arthrosis (Multiple sites)	0.000	0.998	0.002
C25.0 Head of pancreas	0.000	0.998	0.002
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
D48.1 Connective and other soft tissue	0.000	0.998	0.002
G12.2 Motor neuron disease	0.000	0.998	0.002
M19.21 Other secondary arthrosis (Shoulder region)	0.000	0.998	0.001
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
D46 Myelodysplastic syndromes	0.000	0.998	0.002
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.002
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
I26 Pulmonary embolism	0.002	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.998	0.001
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
M19.81 Other specified arthrosis (Shoulder region)	0.000	0.998	0.001
M79.60 Pain in limb (Multiple sites)	0.000	0.998	0.002
R22.9 Localised swelling, mass and lump, unspecified	0.002	0.998	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.000	0.998	0.001
M19.86 Other specified arthrosis (Lower leg)	0.000	0.998	0.001
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.000	0.998	0.001
M19.83 Other specified arthrosis (Forearm)	0.000	0.998	0.001
M19.82 Other specified arthrosis (Upper arm)	0.000	0.998	0.001
M19.80 Other specified arthrosis (Multiple sites)	0.000	0.998	0.001
M19.1 Posttraumatic arthrosis of other joints	0.000	0.998	0.001
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.001
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.001
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.001
M19.88 Other specified arthrosis (Other)	0.000	0.998	0.001
M19.84 Other specified arthrosis (Hand)	0.000	0.998	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.001
K62.0 Anal polyp	0.000	0.998	0.002
M19.89 Other specified arthrosis (Site unspecified)	0.000	0.998	0.001
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.001
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.001
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.001	0.998	0.000
T78.4 Allergy, unspecified	0.001	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.001
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.001
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.001
M22.4 Chondromalacia patellae	0.000	0.998	0.001
D46.4 Refractory anaemia, unspecified	0.000	0.999	0.001
D48.7 Other specified sites	0.000	0.999	0.001
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.999	0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.999	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.999	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.999	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.999	0.001
T88.5 Other complications of anaesthesia	0.000	0.999	0.001
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.999	0.001
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.999	0.001
T88.9 Complication of surgical and medical care, unspecified	0.000	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.999	0.001
D48.4 Peritoneum	0.000	0.999	0.001
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.999	0.001
F03 Unspecified dementia	0.000	0.999	0.001
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.999	0.001
T83.2 Mechanical complication of graft of urinary organ	0.000	0.999	0.001
T88.2 Shock due to anaesthesia	0.000	0.999	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.999	0.001
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.999	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.999	0.001
K83.1 Obstruction of bile duct	0.001	0.999	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.999	0.001
C25 Malignant neoplasm of pancreas	0.000	0.999	0.001
N64 Other disorders of breast	0.000	0.999	0.001
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.999	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.999	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.999	0.001
M79.62 Pain in limb (Upper arm)	0.001	0.999	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.999	0.001
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
R22.0 Localised swelling, mass and lump, head	0.001	0.999	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.999	0.001
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.999	0.001
S72.01 Fracture of neck of femur (open)	0.001	0.999	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.999	0.001
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.001	0.999	0.000
D48.6 Breast	0.000	0.999	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.999	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
M10.96 Gout, unspecified (Lower leg)	0.001	0.999	0.000
D48.3 Retroperitoneum	0.000	0.999	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.999	0.001
C25.7 Other parts of pancreas	0.000	0.999	0.001
C25.2 Tail of pancreas	0.000	0.999	0.001
D48.5 Skin	0.000	0.999	0.001
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.999	0.001
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.999	0.001
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.999	0.001
N64.2 Atrophy of breast	0.000	0.999	0.001
R22.3 Localised swelling, mass and lump, upper limb	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.999	0.001
T88.0 Infection following immunisation	0.000	0.999	0.001
M18 Arthrosis of first carpometacarpal joint	0.000	0.999	0.001
C25.4 Endocrine pancreas	0.000	0.999	0.001
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.999	0.001
K91.1 Postgastric surgery syndromes	0.001	0.999	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.001	0.999	0.000
M10.9 Gout, unspecified	0.001	0.999	0.000
N64.9 Disorder of breast, unspecified	0.000	0.999	0.001
N64.0 Fissure and fistula of nipple	0.000	0.999	0.001
Q78.0 Osteogenesis imperfecta	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.999	0.001
Z45.8 Adjustment and management of other implanted devices	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.999	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.001	0.999	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.999	0.001
M79.6 Pain in limb	0.000	0.999	0.001
O72.1 Other immediate postpartum haemorrhage	0.000	0.999	0.001
Q66.8 Other congenital deformities of feet	0.000	0.999	0.001
R22.7 Localised swelling, mass and lump, multiple sites	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.000	0.999	0.001
T85.2 Mechanical complication of intraocular lens	0.000	0.999	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.999	0.001
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
J36 Peritonsillar abscess	0.000	0.999	0.001
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.000	0.999	0.001
C25.3 Pancreatic duct	0.000	0.999	0.001
C25.1 Body of pancreas	0.000	0.999	0.001
D44.9 Endocrine gland, unspecified	0.000	0.999	0.001
H83.0 Labyrinthitis	0.001	0.999	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.999	0.001
N64.3 Galactorrhoea not associated with childbirth	0.000	0.999	0.001
Q76.5 Cervical rib	0.000	0.999	0.001
S00.8 Superficial injury of other parts of head	0.000	0.999	0.001
Q78 Other osteochondrodysplasias	0.000	0.999	0.001
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
D44.1 Adrenal gland	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.999	0.001
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
T88.4 Failed or difficult intubation	0.000	0.999	0.001
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.999	0.001
Q76 Congenital malformations of spine and bony thorax	0.000	0.999	0.001
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.000	0.999	0.001
D48.0 Bone and articular cartilage	0.000	0.999	0.001
L29.0 Pruritus ani	0.001	0.999	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.999	0.001
Q78.2 Osteopetrosis	0.000	0.999	0.001
S92.5 Fracture of other toe	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.999	0.001
G12 Spinal muscular atrophy and related syndromes	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.000	0.999	0.001
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.999	0.001
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.999	0.001
M10.98 Gout, unspecified (Other)	0.001	0.999	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M10.91 Gout, unspecified (Shoulder region)	0.001	0.999	0.000
M10.90 Gout, unspecified (Multiple sites)	0.001	0.999	0.000
M79.68 Pain in limb (Other)	0.000	0.999	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
D44.8 Pluriglandular involvement	0.000	0.999	0.001
F05.9 Delirium, unspecified	0.000	0.999	0.001
F07.2 Postconcussional syndrome	0.000	0.999	0.001
G45.3 Amaurosis fugax	0.000	0.999	0.001
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
N64.8 Other specified disorders of breast	0.000	0.999	0.001
T87.3 Neuroma of amputation stump	0.000	0.999	0.001
S42.41 Fracture of lower end of humerus (open)	0.000	0.999	0.001
F02.0 Dementia in Pick's disease	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.000	0.999	0.001
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.999	0.001
M10.97 Gout, unspecified (Ankle and foot)	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.001	0.999	0.000
M25.46 Effusion of joint (Lower leg)	0.001	0.999	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.999	0.001
K91.5 Postcholecystectomy syndrome	0.001	0.999	0.000
N64.4 Mastodynia	0.000	0.999	0.001
Q65.0 Congenital dislocation of hip, unilateral	0.000	0.999	0.001
Q66.0 Talipes equinovarus	0.000	0.999	0.001
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.999	0.001
Q76.8 Other congenital malformations of bony thorax	0.000	0.999	0.001
Q76.7 Congenital malformation of sternum	0.000	0.999	0.001
Q76.6 Other congenital malformations of ribs	0.000	0.999	0.001
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.999	0.001
Q76.2 Congenital spondylolisthesis	0.000	0.999	0.001
Q78.9 Osteochondrodysplasia, unspecified	0.000	0.999	0.001
Q78.8 Other specified osteochondrodysplasias	0.000	0.999	0.001
Q78.6 Multiple congenital exostoses	0.000	0.999	0.001
Q78.5 Metaphyseal dysplasia	0.000	0.999	0.001
Q78.4 Enchondromatosis	0.000	0.999	0.001
Q78.3 Progressive diaphyseal dysplasia	0.000	0.999	0.001
Q78.1 Polyostotic fibrous dysplasia	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.000	0.999	0.001
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
D44.5 Pineal gland	0.000	0.999	0.001
D44.2 Parathyroid gland	0.000	0.999	0.001
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.999	0.001
F02.2 Dementia in Huntington's disease	0.000	0.999	0.001
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.999	0.001
G12.9 Spinal muscular atrophy, unspecified	0.000	0.999	0.001
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.999	0.001
G12.1 Other inherited spinal muscular atrophy	0.000	0.999	0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.999	0.001
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.000	0.999	0.001
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
T86.3 Heart-lung transplant failure and rejection	0.000	0.999	0.001
T86.2 Heart transplant failure and rejection	0.000	0.999	0.001
T87.2 Complications of other reattached body part	0.000	0.999	0.001
T87.1 Complications of reattached (part of) lower extremity	0.000	0.999	0.001
T87.0 Complications of reattached (part of) upper extremity	0.000	0.999	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
Q74 Other congenital malformations of limb(s)	0.000	0.999	0.001
M79.61 Pain in limb (Shoulder region)	0.000	0.999	0.001
D44.7 Aortic body and other paraganglia	0.000	0.999	0.001
D44.6 Carotid body	0.000	0.999	0.001
E83.1 Disorders of iron metabolism	0.001	0.999	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.999	0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999	0.000
L29.9 Pruritus, unspecified	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.000	0.999	0.001
Q66.6 Other congenital valgus deformities of feet	0.000	0.999	0.001
Q66.5 Congenital pes planus	0.000	0.999	0.001
Q66.4 Talipes calcaneovalgus	0.000	0.999	0.001
Q66.1 Talipes calcaneovarus	0.000	0.999	0.001
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.000	0.999	0.001
Q76.1 Klippel-Feil syndrome	0.000	0.999	0.001
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
T43.2 Other and unspecified antidepressants	0.001	0.999	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.999	0.001
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
M10.94 Gout, unspecified (Hand)	0.001	0.999	0.000
M10.92 Gout, unspecified (Upper arm)	0.001	0.999	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
D44.0 Thyroid gland	0.000	0.999	0.001
F07.0 Organic personality disorder	0.000	0.999	0.001
M81.4 Drug-induced osteoporosis	0.000	0.999	0.001
N64.1 Fat necrosis of breast	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.000	0.999	0.001
Q65.6 Unstable hip	0.000	0.999	0.001
Q65.5 Congenital subluxation of hip, unspecified	0.000	0.999	0.001
Q65.4 Congenital subluxation of hip, bilateral	0.000	0.999	0.001
Q65.3 Congenital subluxation of hip, unilateral	0.000	0.999	0.001
Q65.2 Congenital dislocation of hip, unspecified	0.000	0.999	0.001
Q65.1 Congenital dislocation of hip, bilateral	0.000	0.999	0.001
Q66.7 Pes cavus	0.000	0.999	0.001
S90.0 Contusion of ankle	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.999	0.001
T86.4 Liver transplant failure and rejection	0.000	0.999	0.001
T87.5 Necrosis of amputation stump	0.000	0.999	0.001
T87.4 Infection of amputation stump	0.000	0.999	0.001
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.999	0.001
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.999	0.001
Q70 Syndactyly	0.000	0.999	0.001
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
F05.1 Delirium superimposed on dementia	0.000	0.999	0.001
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
K12.2 Cellulitis and abscess of mouth	0.000	0.999	0.001
O32.8 Maternal care for other malpresentation of foetus	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.000	0.999	0.001
Q66.3 Other congenital varus deformities of feet	0.000	0.999	0.001
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.000	0.999	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.999	0.001
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.000	0.999	0.001
Q75 Other congenital malformations of skull and face bones	0.000	0.999	0.001
Q73 Reduction defects of unspecified limb	0.000	0.999	0.001
Q72 Reduction defects of lower limb	0.000	0.999	0.001
Q71 Reduction defects of upper limb	0.000	0.999	0.001
Q69 Polydactyly	0.000	0.999	0.001
Q68 Other congenital musculoskeletal deformities	0.000	0.999	0.001
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.000	0.999	0.001
M81.48 Drug-induced osteoporosis (Other)	0.000	0.999	0.001
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.999	0.001
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.999	0.001
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.999	0.001
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.999	0.001
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.999	0.001
M81.89 Other osteoporosis (Site unspecified)	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.001	0.999	0.000
D42.1 Spinal meninges	0.000	0.999	0.001
D42.0 Cerebral meninges	0.000	0.999	0.001
F05.8 Other delirium	0.000	0.999	0.001
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
F07.1 Postencephalitic syndrome	0.000	0.999	0.001
H33.0 Retinal detachment with retinal break	0.001	0.999	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.999	0.001
Q67.4 Other congenital deformities of skull, face and jaw	0.000	0.999	0.001
Q70.3 Webbed toes	0.000	0.999	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.000	0.999	0.001
Q74.8 Other specified congenital malformations of limb(s)	0.000	0.999	0.001
Q74.3 Arthrogryposis multiplex congenita	0.000	0.999	0.001
Q79.1 Other congenital malformations of diaphragm	0.000	0.999	0.001
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.999	0.000
T80.6 Other serum reactions	0.000	0.999	0.001
T80.5 Anaphylactic shock due to serum	0.000	0.999	0.001
T80.4 Rh incompatibility reaction	0.000	0.999	0.001
T80.3 ABO incompatibility reaction	0.000	0.999	0.001
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.999	0.001
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
N40 Hyperplasia of prostate	0.000	0.999	0.001
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.001	0.999	0.000
M79.63 Pain in limb (Forearm)	0.000	0.999	0.001
M79.79 Fibromyalgia (Site unspecified)	0.000	0.999	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
D42.9 Meninges, unspecified	0.000	0.999	0.001
D44.3 Pituitary gland	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.999	0.001
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
M81.8 Other osteoporosis	0.000	0.999	0.001
M81.2 Osteoporosis of disuse	0.000	0.999	0.001
Q68.8 Other specified congenital musculoskeletal deformities	0.000	0.999	0.001
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.999	0.001
Q68.4 Congenital bowing of tibia and fibula	0.000	0.999	0.001
Q68.3 Congenital bowing of femur	0.000	0.999	0.001
Q68.2 Congenital deformity of knee	0.000	0.999	0.001
Q68.1 Congenital deformity of hand	0.000	0.999	0.001
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.999	0.001
Q69.9 Polydactyly, unspecified	0.000	0.999	0.001
Q69.2 Accessory toe(s)	0.000	0.999	0.001
Q69.1 Accessory thumb(s)	0.000	0.999	0.001
Q69.0 Accessory finger(s)	0.000	0.999	0.001
Q70.9 Syndactyly, unspecified	0.000	0.999	0.001
Q70.4 Polysyndactyly	0.000	0.999	0.001
Q70.2 Fused toes	0.000	0.999	0.001
Q70.1 Webbed fingers	0.000	0.999	0.001
Q70.0 Fused fingers	0.000	0.999	0.001
Q71.9 Reduction defect of upper limb, unspecified	0.000	0.999	0.001
Q71.8 Other reduction defects of upper limb(s)	0.000	0.999	0.001
Q71.6 Lobster-claw hand	0.000	0.999	0.001
Q71.5 Longitudinal reduction defect of ulna	0.000	0.999	0.001
Q71.4 Longitudinal reduction defect of radius	0.000	0.999	0.001
Q71.3 Congenital absence of hand and finger(s)	0.000	0.999	0.001
Q71.2 Congenital absence of both forearm and hand	0.000	0.999	0.001
Q71.1 Congenital absence of upper arm and forearm with hand present	0.000	0.999	0.001
Q71.0 Congenital complete absence of upper limb(s)	0.000	0.999	0.001
Q72.9 Reduction defect of lower limb, unspecified	0.000	0.999	0.001
Q72.8 Other reduction defects of lower limb(s)	0.000	0.999	0.001
Q72.7 Split foot	0.000	0.999	0.001
Q72.6 Longitudinal reduction defect of fibula	0.000	0.999	0.001
Q72.5 Longitudinal reduction defect of tibia	0.000	0.999	0.001
Q72.4 Longitudinal reduction defect of femur	0.000	0.999	0.001
Q72.3 Congenital absence of foot and toe(s)	0.000	0.999	0.001
Q72.2 Congenital absence of both lower leg and foot	0.000	0.999	0.001
Q72.1 Congenital absence of thigh and lower leg with foot present	0.000	0.999	0.001
Q72.0 Congenital complete absence of lower limb(s)	0.000	0.999	0.001
Q73.8 Other reduction defects of unspecified limb(s)	0.000	0.999	0.001
Q73.1 Phocomelia, unspecified limb(s)	0.000	0.999	0.001
Q73.0 Congenital absence of unspecified limb(s)	0.000	0.999	0.001
Q74.1 Congenital malformation of knee	0.000	0.999	0.001
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.000	0.999	0.001
Q79.8 Other congenital malformations of musculoskeletal system	0.000	0.999	0.001
Q79.6 Ehlers-Danlos syndrome	0.000	0.999	0.001
Q79.5 Other congenital malformations of abdominal wall	0.000	0.999	0.001
Q79.4 Prune belly syndrome	0.000	0.999	0.001
Q79.3 Gastroschisis	0.000	0.999	0.001
Q79.2 Exomphalos	0.000	0.999	0.001
Q83.1 Accessory breast	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.999	0.000
D45 Polycythaemia vera	0.000	0.999	0.001
M81 Osteoporosis without pathological fracture	0.000	0.999	0.001
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations