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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs57584581
log Bayes Factor = 29.3193
Chromosome 4   position 185,951,230  (GRCh37) Explore rs57584581 on Ensembl!
Variant rs57584581 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M25.5 Pain in joint
0.999 0.001 0.000
M25 Other joint disorders, not elsewhere classified
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
J30-J39 Other diseases of upper respiratory tract
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
I73 Other peripheral vascular diseases
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
J09-J18 Influenza and pneumonia
0.989 0.011 0.000
I73.9 Peripheral vascular disease, unspecified
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
J18 Pneumonia, organism unspecified
0.981 0.019 0.000
S09 Other and unspecified injuries of head
0.981 0.019 0.000
R59 Enlarged lymph nodes
0.980 0.020 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.978 0.022 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.976 0.024 0.000
J18.1 Lobar pneumonia, unspecified
0.973 0.027 0.000
I22 Subsequent myocardial infarction
0.973 0.027 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.972 0.028 0.000
S01 Open wound of head
0.972 0.028 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.970 0.030 0.000
Z50 Care involving use of rehabilitation procedures
0.969 0.031 0.000
S09.9 Unspecified injury of head
0.969 0.031 0.000
M25.51 Pain in joint (Shoulder region)
0.967 0.033 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.966 0.034 0.000
M25.57 Pain in joint (Ankle and foot)
0.963 0.037 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.962 0.038 0.000
I21 Acute myocardial infarction
0.958 0.042 0.000
R59.0 Localised enlarged lymph nodes
0.958 0.042 0.000
R63 Symptoms and signs concerning food and fluid intake
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.955 0.045 0.000
A00-A09 Intestinal infectious diseases
0.955 0.045 0.000
I60-I69 Cerebrovascular diseases
0.954 0.046 0.000
J34 Other disorders of nose and nasal sinuses
0.952 0.048 0.000
M25.56 Pain in joint (Lower leg)
0.952 0.048 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.948 0.052 0.000
J33 Nasal polyp
0.945 0.055 0.000
Chapter XX External causes of morbidity and mortality
0.939 0.061 0.000
J00-J06 Acute upper respiratory infections
0.938 0.062 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.935 0.065 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.932 0.068 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.932 0.068 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.930 0.070 0.000
J32 Chronic sinusitis
0.928 0.072 0.000
S60-S69 Injuries to the wrist and hand
0.925 0.075 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.924 0.075 0.000
G30-G32 Other degenerative diseases of the nervous system
0.922 0.078 0.000
J02 Acute pharyngitis
0.921 0.079 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.919 0.081 0.000
O60-O75 Complications of labour and delivery
0.917 0.083 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.916 0.084 0.000
B35-B49 Mycoses
0.912 0.088 0.000
D00-D09 In situ neoplasms
0.909 0.091 0.000
J02.9 Acute pharyngitis, unspecified
0.909 0.091 0.000
T66-T78 Other and unspecified effects of external causes
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.907 0.093 0.000
Chapter VIII Diseases of the ear and mastoid process
0.905 0.095 0.000
S01.8 Open wound of other parts of head
0.902 0.098 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.902 0.098 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.901 0.099 0.000
I77 Other disorders of arteries and arterioles
0.896 0.104 0.000
I69 Sequelae of cerebrovascular disease
0.896 0.104 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.895 0.105 0.000
J34.2 Deviated nasal septum
0.894 0.106 0.000
R55 Syncope and collapse
0.894 0.106 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.893 0.107 0.000
R26 Abnormalities of gait and mobility
0.889 0.111 0.000
Z51 Other medical care
0.889 0.111 0.000
R63.0 Anorexia
0.888 0.112 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.888 0.112 0.000
S70-S79 Injuries to the hip and thigh
0.887 0.113 0.000
R57 Shock, not elsewhere classified
0.882 0.117 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.882 0.118 0.000
G70-G73 Diseases of myoneural junction and muscle
0.880 0.120 0.000
Z51.2 Other chemotherapy
0.880 0.120 0.000
J33.0 Polyp of nasal cavity
0.879 0.121 0.000
S02 Fracture of skull and facial bones
0.875 0.125 0.000
E70-E90 Metabolic disorders
0.874 0.126 0.000
I20 Angina pectoris
0.874 0.126 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.873 0.127 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.868 0.132 0.000
J95-J99 Other diseases of the respiratory system
0.867 0.133 0.000
C77.3 Axillary and upper limb lymph nodes
0.867 0.133 0.000
C77.0 Lymph nodes of head, face and neck
0.864 0.136 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.863 0.137 0.000
I21.4 Acute subendocardial myocardial infarction
0.862 0.137 0.000
J60-J70 Lung diseases due to external agents
0.862 0.138 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.862 0.138 0.000
T39.1 4-Aminophenol derivatives
0.860 0.140 0.000
W00-W19 Falls
0.859 0.141 0.000
S01.2 Open wound of nose
0.859 0.141 0.000
Z50.1 Other physical therapy
0.857 0.143 0.000
J33.8 Other polyp of sinus
0.856 0.144 0.000
M50-M54 Other dorsopathies
0.855 0.145 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.855 0.145 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.853 0.147 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.853 0.147 0.000
L60-L75 Disorders of skin appendages
0.850 0.150 0.000
R59.1 Generalised enlarged lymph nodes
0.850 0.150 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.849 0.151 0.000
C78.7 Secondary malignant neoplasm of liver
0.848 0.152 0.000
M15-M19 Arthrosis
0.846 0.154 0.000
H60-H62 Diseases of external ear
0.845 0.155 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.844 0.156 0.000
T78 Adverse effects, not elsewhere classified
0.844 0.156 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.842 0.158 0.000
R52 Pain, not elsewhere classified
0.841 0.159 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.839 0.161 0.000
S50-S59 Injuries to the elbow and forearm
0.838 0.162 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.835 0.165 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.834 0.165 0.000
S01.0 Open wound of scalp
0.833 0.167 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.833 0.167 0.000
I74 Arterial embolism and thrombosis
0.833 0.167 0.000
R47-R49 Symptoms and signs involving speech and voice
0.832 0.168 0.000
B37 Candidiasis
0.829 0.171 0.000
M25.53 Pain in joint (Forearm)
0.828 0.172 0.000
Z50.0 Cardiac rehabilitation
0.827 0.173 0.000
J20-J22 Other acute lower respiratory infections
0.826 0.174 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.826 0.174 0.000
J32.0 Chronic maxillary sinusitis
0.826 0.174 0.000
M54 Dorsalgia
0.825 0.175 0.000
M91-M94 Chondropathies
0.822 0.178 0.000
I21.9 Acute myocardial infarction, unspecified
0.822 0.178 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.821 0.179 0.000
M45-M49 Spondylopathies
0.821 0.179 0.000
Z48 Other surgical follow-up care
0.819 0.181 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.818 0.182 0.000
I25 Chronic ischaemic heart disease
0.818 0.182 0.000
I73.0 Raynaud's syndrome
0.814 0.186 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.813 0.187 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.812 0.188 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
O40 Polyhydramnios
0.810 0.190 0.000
Q60-Q64 Congenital malformations of the urinary system
0.810 0.190 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.807 0.193 0.000
O63 Long labour
0.807 0.193 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.806 0.194 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.806 0.194 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.806 0.194 0.000
S40-S49 Injuries to the shoulder and upper arm
0.805 0.195 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.804 0.196 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.803 0.197 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.803 0.197 0.000
C15-C26 Malignant neoplasms of digestive organs
0.802 0.198 0.000
D06 Carcinoma in situ of cervix uteri
0.802 0.198 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.802 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.802 0.198 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.802 0.198 0.000
I77.1 Stricture of artery
0.801 0.199 0.000
V10-V19 Pedal cyclist injured in transport accident
0.800 0.200 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.799 0.201 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.799 0.201 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.796 0.204 0.000
M24 Other specific joint derangements
0.796 0.204 0.000
M54.5 Low back pain
0.795 0.205 0.000
R25 Abnormal involuntary movements
0.795 0.205 0.000
T39.0 Salicylates
0.795 0.205 0.000
G82 Paraplegia and tetraplegia
0.795 0.205 0.000
R42 Dizziness and giddiness
0.794 0.206 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.793 0.207 0.000
R63.5 Abnormal weight gain
0.792 0.208 0.000
I63 Cerebral infarction
0.789 0.211 0.000
O00-O08 Pregnancy with abortive outcome
0.788 0.211 0.000
H61 Other disorders of external ear
0.788 0.212 0.000
S62 Fracture at wrist and hand level
0.788 0.212 0.000
M16 Coxarthrosis [arthrosis of hip]
0.787 0.213 0.000
E00-E07 Disorders of thyroid gland
0.786 0.214 0.000
E10-E14 Diabetes mellitus
0.786 0.214 0.000
Z50.2 Alcohol rehabilitation
0.786 0.214 0.000
M35 Other systemic involvement of connective tissue
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
O42 Premature rupture of membranes
0.784 0.216 0.000
O41 Other disorders of amniotic fluid and membranes
0.784 0.216 0.000
M25.4 Effusion of joint
0.784 0.216 0.000
M21 Other acquired deformities of limbs
0.782 0.218 0.000
I26 Pulmonary embolism
0.781 0.219 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.779 0.221 0.000
C77.4 Inguinal and lower limb lymph nodes
0.779 0.221 0.000
Z50.8 Care involving use of rehabilitation procedures
0.778 0.222 0.000
I72 Other aneurysm
0.777 0.223 0.000
R58 Haemorrhage, not elsewhere classified
0.777 0.223 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.773 0.226 0.000
M65-M68 Disorders of synovium and tendon
0.773 0.226 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.773 0.227 0.000
O48 Prolonged pregnancy
0.773 0.227 0.000
E20-E35 Disorders of other endocrine glands
0.773 0.227 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.772 0.227 0.000
H90-H95 Other disorders of ear
0.772 0.228 0.000
M25.54 Pain in joint (Hand)
0.772 0.228 0.000
S20-S29 Injuries to the thorax
0.771 0.229 0.000
Z40 Prophylactic surgery
0.770 0.230 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.769 0.230 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.769 0.231 0.000
M25.59 Pain in joint (Site unspecified)
0.769 0.231 0.000
M25.8 Other specified joint disorders
0.768 0.232 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.767 0.233 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
G81 Hemiplegia
0.766 0.234 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.766 0.234 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.765 0.235 0.000
O85-O92 Complications predominantly related to the puerperium
0.765 0.235 0.000
M25.52 Pain in joint (Upper arm)
0.765 0.235 0.000
I20.0 Unstable angina
0.764 0.236 0.000
S01.4 Open wound of cheek and temporomandibular area
0.764 0.236 0.000
J69 Pneumonitis due to solids and liquids
0.762 0.238 0.000
B65-B83 Helminthiases
0.762 0.238 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.762 0.238 0.000
R60 Oedema, not elsewhere classified
0.762 0.238 0.000
S60 Superficial injury of wrist and hand
0.762 0.238 0.000
R57.2 Septic shock
0.761 0.239 0.000
M25.9 Joint disorder, unspecified
0.759 0.241 0.000
J30 Vasomotor and allergic rhinitis
0.759 0.241 0.000
J34.3 Hypertrophy of nasal turbinates
0.759 0.241 0.000
L72.0 Epidermal cyst
0.758 0.242 0.000
G80 Infantile cerebral palsy
0.758 0.242 0.000
L91 Hypertrophic disorders of skin
0.758 0.242 0.000
I61 Intracerebral haemorrhage
0.758 0.242 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.757 0.243 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
X20-X29 Contact with venomous animals and plants
0.755 0.245 0.000
Z48.8 Other specified surgical follow-up care
0.754 0.246 0.000
R13 Dysphagia
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.754 0.246 0.000
R61 Hyperhidrosis
0.753 0.247 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.753 0.247 0.000
M60-M63 Disorders of muscles
0.752 0.247 0.000
I25.2 Old myocardial infarction
0.752 0.248 0.000
J18.0 Bronchopneumonia, unspecified
0.751 0.248 0.000
J32.2 Chronic ethmoidal sinusitis
0.751 0.249 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.750 0.250 0.000
G62 Other polyneuropathies
0.750 0.250 0.000
J32.4 Chronic pansinusitis
0.749 0.251 0.000
D45 Polycythaemia vera
0.749 0.251 0.000
G71 Primary disorders of muscles
0.749 0.251 0.000
R54 Senility
0.748 0.252 0.000
G20-G26 Extrapyramidal and movement disorders
0.748 0.252 0.000
H61.0 Perichondritis of external ear
0.747 0.253 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.746 0.254 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.745 0.255 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
D04 Carcinoma in situ of skin
0.743 0.257 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.743 0.257 0.000
J18.9 Pneumonia, unspecified
0.742 0.258 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.741 0.259 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.740 0.260 0.000
J90-J94 Other diseases of pleura
0.739 0.261 0.000
O62 Abnormalities of forces of labour
0.739 0.261 0.000
I60 Subarachnoid haemorrhage
0.739 0.261 0.000
B15-B19 Viral hepatitis
0.738 0.262 0.000
B44 Aspergillosis
0.737 0.263 0.000
R50 Fever of unknown origin
0.733 0.267 0.000
C78.0 Secondary malignant neoplasm of lung
0.732 0.268 0.000
M05-M14 Inflammatory polyarthropathies
0.732 0.268 0.000
T78.3 Angioneurotic oedema
0.732 0.268 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.732 0.268 0.000
S79 Other and unspecified injuries of hip and thigh
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.731 0.269 0.000
W50-W64 Exposure to animate mechanical forces
0.731 0.269 0.000
W20-W49 Exposure to inanimate mechanical forces
0.730 0.270 0.000
C15 Malignant neoplasm of oesophagus
0.730 0.270 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.730 0.270 0.000
R47 Speech disturbances, not elsewhere classified
0.729 0.271 0.000
S02.4 Fracture of malar and maxillary bones
0.729 0.271 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.728 0.272 0.000
L89 Decubitus ulcer
0.728 0.272 0.000
R27 Other lack of coordination
0.726 0.274 0.000
I25.5 Ischaemic cardiomyopathy
0.726 0.274 0.000
D06.9 Cervix, unspecified
0.725 0.275 0.000
S51 Open wound of forearm
0.725 0.275 0.000
G70 Myasthenia gravis and other myoneural disorders
0.724 0.275 0.000
I69.3 Sequelae of cerebral infarction
0.724 0.276 0.000
M19 Other arthrosis
0.723 0.276 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.723 0.277 0.000
J35 Chronic diseases of tonsils and adenoids
0.722 0.278 0.000
B37.3 Candidiasis of vulva and vagina
0.722 0.278 0.000
Z49 Care involving dialysis
0.721 0.278 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.721 0.279 0.000
I27 Other pulmonary heart diseases
0.721 0.279 0.000
C77.5 Intrapelvic lymph nodes
0.721 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.721 0.279 0.000
O43 Placental disorders
0.720 0.280 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.720 0.280 0.000
O30 Multiple gestation
0.719 0.281 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.719 0.281 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.718 0.281 0.000
M48 Other spondylopathies
0.718 0.282 0.000
W19 Unspecified fall
0.718 0.282 0.000
E83 Disorders of mineral metabolism
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C34 Malignant neoplasm of bronchus and lung
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
M25.58 Pain in joint (Other)
0.716 0.284 0.000
M25.3 Other instability of joint
0.716 0.284 0.000
M25.2 Flail joint
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
M25.0 Haemarthrosis
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
O23 Infections of genito-urinary tract in pregnancy
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.715 0.285 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.714 0.286 0.000
J37 Chronic laryngitis and laryngotracheitis
0.714 0.286 0.000
C90.0 Multiple myeloma
0.714 0.286 0.000
S01.5 Open wound of lip and oral cavity
0.714 0.286 0.000
C77.9 Lymph node, unspecified
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
Z36 Antenatal screening
0.713 0.287 0.000
R57.0 Cardiogenic shock
0.713 0.287 0.000
S69 Other and unspecified injuries of wrist and hand
0.712 0.288 0.000
E86 Volume depletion
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
I73.8 Other specified peripheral vascular diseases
0.711 0.289 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.711 0.289 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.711 0.289 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.710 0.290 0.000
Z47 Other orthopaedic follow-up care
0.710 0.290 0.000
A30-A49 Other bacterial diseases
0.710 0.290 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
J17 Pneumonia in diseases classified elsewhere
0.709 0.291 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.709 0.291 0.000
J12 Viral pneumonia, not elsewhere classified
0.709 0.291 0.000
J11 Influenza, virus not identified
0.709 0.291 0.000
J10 Influenza due to identified influenza virus
0.709 0.291 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
J09 Influenza due to certain identified influenza virus
0.709 0.291 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.708 0.292 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.708 0.292 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.708 0.292 0.000
C77.8 Lymph nodes of multiple regions
0.708 0.292 0.000
T85.2 Mechanical complication of intraocular lens
0.708 0.292 0.000
D60-D64 Aplastic and other anaemias
0.708 0.292 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.708 0.292 0.000
I62 Other nontraumatic intracranial haemorrhage
0.707 0.293 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.707 0.293 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.707 0.293 0.000
T78.4 Allergy, unspecified
0.706 0.294 0.000
O61 Failed induction of labour
0.705 0.295 0.000
I20.1 Angina pectoris with documented spasm
0.705 0.295 0.000
H93 Other disorders of ear, not elsewhere classified
0.705 0.295 0.000
Q80-Q89 Other congenital malformations
0.704 0.295 0.000
B37.9 Candidiasis, unspecified
0.704 0.296 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.704 0.296 0.000
J18.8 Other pneumonia, organism unspecified
0.703 0.296 0.000
J18.2 Hypostatic pneumonia, unspecified
0.703 0.296 0.000
S09.8 Other specified injuries of head
0.703 0.297 0.000
S09.7 Multiple injuries of head
0.703 0.297 0.000
S09.2 Traumatic rupture of ear drum
0.703 0.297 0.000
S09.1 Injury of muscle and tendon of head
0.703 0.297 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.703 0.297 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.703 0.297 0.000
G40-G47 Episodic and paroxysmal disorders
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
E78.0 Pure hypercholesterolaemia
0.703 0.297 0.000
M35.0 Sicca syndrome [Sjogren]
0.703 0.297 0.000
I05-I09 Chronic rheumatic heart diseases
0.702 0.297 0.000
R63.4 Abnormal weight loss
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.702 0.298 0.000
M16.1 Other primary coxarthrosis
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
J22 Unspecified acute lower respiratory infection
0.702 0.298 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.702 0.298 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.701 0.298 0.000
Z45 Adjustment and management of implanted device
0.701 0.298 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.701 0.299 0.000
O02 Other abnormal products of conception
0.701 0.299 0.000
O63.1 Prolonged second stage (of labour)
0.701 0.299 0.000
Z54 Convalescence
0.699 0.300 0.000
Z52 Donors of organs and tissues
0.699 0.300 0.000
Z44 Fitting and adjustment of external prosthetic device
0.699 0.300 0.000
S72 Fracture of femur
0.699 0.301 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.698 0.302 0.000
S01.9 Open wound of head, part unspecified
0.698 0.302 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.697 0.302 0.000
I22.8 Subsequent myocardial infarction of other sites
0.697 0.303 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.697 0.303 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.697 0.303 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.697 0.303 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.697 0.303 0.000
T82.3 Mechanical complication of other vascular grafts
0.697 0.303 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.697 0.303 0.000
T82.1 Mechanical complication of cardiac electronic device
0.697 0.303 0.000
Q00-Q07 Congenital malformations of the nervous system
0.697 0.303 0.000
S01.7 Multiple open wounds of head
0.697 0.303 0.000
S01.3 Open wound of ear
0.697 0.303 0.000
R14 Flatulence and related conditions
0.696 0.304 0.000
R68 Other general symptoms and signs
0.695 0.305 0.000
R04 Haemorrhage from respiratory passages
0.695 0.305 0.000
M94 Other disorders of cartilage
0.695 0.305 0.000
Z50.6 Orthoptic training
0.695 0.305 0.000
Z50.3 Drug rehabilitation
0.695 0.305 0.000
C16 Malignant neoplasm of stomach
0.694 0.306 0.000
O45 Premature separation of placenta [abruptio placentae]
0.693 0.307 0.000
O44 Placenta praevia
0.693 0.307 0.000
O33 Maternal care for known or suspected disproportion
0.693 0.307 0.000
O31 Complications specific to multiple gestation
0.693 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.693 0.307 0.000
W07 Fall involving chair
0.692 0.308 0.000
J69.0 Pneumonitis due to food and vomit
0.691 0.309 0.000
R52.2 Other chronic pain
0.691 0.309 0.000
X60-X84 Intentional self-harm
0.690 0.309 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.690 0.309 0.000
O16 Unspecified maternal hypertension
0.690 0.310 0.000
S64 Injury of nerves at wrist and hand level
0.690 0.310 0.000
C81 Hodgkin's disease
0.689 0.311 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.687 0.312 0.000
M54.59 Low back pain (Site unspecified)
0.687 0.313 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.687 0.313 0.000
O47 False labour
0.687 0.313 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.687 0.313 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.687 0.313 0.000
M54.56 Low back pain (Lumbar region)
0.687 0.313 0.000
A08 Viral and other specified intestinal infections
0.686 0.314 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.686 0.314 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.686 0.314 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.685 0.315 0.000
R63.3 Feeding difficulties and mismanagement
0.685 0.315 0.000
R63.2 Polyphagia
0.685 0.315 0.000
R63.1 Polydipsia
0.685 0.315 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.685 0.315 0.000
L93 Lupus erythematosus
0.685 0.315 0.000
S71 Open wound of hip and thigh
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.684 0.315 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.315 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.684 0.315 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.684 0.315 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.684 0.315 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.684 0.315 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.684 0.315 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.315 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.684 0.315 0.000
T36 Poisoning by systemic antibiotics
0.684 0.315 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.315 0.000
A07 Other protozoal intestinal diseases
0.684 0.315 0.000
A06 Amoebiasis
0.684 0.315 0.000
A05 Other bacterial foodborne intoxications
0.684 0.315 0.000
A03 Shigellosis
0.684 0.315 0.000
A02 Other Salmonella infections
0.684 0.315 0.000
A01 Typhoid and paratyphoid fevers
0.684 0.315 0.000
A00 Cholera
0.684 0.315 0.000
Z60 Problems related to social environment
0.684 0.316 0.000
G90-G99 Other disorders of the nervous system
0.684 0.316 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.684 0.316 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.684 0.316 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.683 0.317 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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