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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59355858
log Bayes Factor = 6.81191
Chromosome 7   position 29,629,005  (GRCh37) Explore rs59355858 on Ensembl!
Variant rs59355858 is part of Cluster X0218

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.993 0.007 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.982 0.018 0.000
E00-E07 Disorders of thyroid gland
0.982 0.018 0.000
O72 Postpartum haemorrhage
0.980 0.020 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.977 0.023 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.976 0.024 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.975 0.025 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.970 0.030 0.000
S40-S49 Injuries to the shoulder and upper arm
0.967 0.033 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.965 0.035 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.963 0.037 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.958 0.042 0.000
O63 Long labour
0.958 0.042 0.000
O72.0 Third-stage haemorrhage
0.955 0.045 0.000
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.939 0.061 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.936 0.064 0.000
Chapter V Mental and behavioural disorders
0.931 0.069 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.927 0.073 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.926 0.074 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.924 0.076 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.922 0.078 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.920 0.080 0.000
C90.0 Multiple myeloma
0.916 0.084 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.911 0.089 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.911 0.089 0.000
C85.1 B-cell lymphoma, unspecified
0.909 0.091 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.909 0.091 0.000
E24 Cushing's syndrome
0.904 0.096 0.000
O63.1 Prolonged second stage (of labour)
0.904 0.096 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.903 0.097 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.899 0.101 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.895 0.105 0.000
O48 Prolonged pregnancy
0.895 0.105 0.000
C77.8 Lymph nodes of multiple regions
0.893 0.107 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.892 0.108 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.892 0.108 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.889 0.111 0.000
S42 Fracture of shoulder and upper arm
0.889 0.111 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.887 0.113 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.883 0.117 0.000
D00-D09 In situ neoplasms
0.881 0.119 0.000
F10.0 Acute intoxication
0.877 0.123 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.876 0.124 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.875 0.125 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.872 0.128 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.872 0.128 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.872 0.128 0.000
O72.1 Other immediate postpartum haemorrhage
0.872 0.128 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.870 0.130 0.000
T51 Toxic effect of alcohol
0.868 0.132 0.000
S90-S99 Injuries to the ankle and foot
0.868 0.132 0.000
C91 Lymphoid leukaemia
0.865 0.135 0.000
S60-S69 Injuries to the wrist and hand
0.859 0.141 0.000
C77.9 Lymph node, unspecified
0.857 0.143 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.856 0.144 0.000
C77.3 Axillary and upper limb lymph nodes
0.854 0.146 0.000
Chapter XX External causes of morbidity and mortality
0.852 0.148 0.000
C81 Hodgkin's disease
0.848 0.152 0.000
Chapter I Certain infectious and parasitic diseases
0.846 0.154 0.000
T42.4 Benzodiazepines
0.844 0.156 0.000
S68 Traumatic amputation of wrist and hand
0.841 0.159 0.000
E06 Thyroiditis
0.839 0.161 0.000
T51.0 Ethanol
0.838 0.162 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.837 0.163 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.835 0.165 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.834 0.166 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.831 0.169 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.831 0.169 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.829 0.171 0.000
T92 Sequelae of injuries of upper limb
0.825 0.175 0.000
T21 Burn and corrosion of trunk
0.823 0.177 0.000
S42.0 Fracture of clavicle
0.817 0.183 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.817 0.183 0.000
F80-F89 Disorders of psychological development
0.816 0.184 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.813 0.187 0.000
T00-T07 Injuries involving multiple body regions
0.812 0.188 0.000
O63.0 Prolonged first stage (of labour)
0.810 0.190 0.000
E16 Other disorders of pancreatic internal secretion
0.810 0.190 0.000
E24.9 Cushing's syndrome, unspecified
0.805 0.195 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.804 0.196 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.803 0.197 0.000
S20-S29 Injuries to the thorax
0.802 0.198 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.800 0.200 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.798 0.202 0.000
T14 Injury of unspecified body region
0.797 0.203 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.787 0.213 0.000
E27 Other disorders of adrenal gland
0.786 0.214 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.785 0.215 0.000
D46 Myelodysplastic syndromes
0.784 0.216 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.784 0.216 0.000
S91 Open wound of ankle and foot
0.780 0.220 0.000
C90.1 Plasma cell leukaemia
0.777 0.223 0.000
E70-E90 Metabolic disorders
0.777 0.223 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.777 0.223 0.000
Q23 Congenital malformations of aortic and mitral valves
0.775 0.225 0.000
T66-T78 Other and unspecified effects of external causes
0.774 0.226 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.774 0.226 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.774 0.226 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.773 0.227 0.000
C71 Malignant neoplasm of brain
0.771 0.229 0.000
A00-A09 Intestinal infectious diseases
0.770 0.230 0.000
D05 Carcinoma in situ of breast
0.767 0.233 0.000
S42.00 Fracture of clavicle (closed)
0.766 0.234 0.000
Q60-Q64 Congenital malformations of the urinary system
0.765 0.235 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.764 0.236 0.000
W20-W49 Exposure to inanimate mechanical forces
0.762 0.238 0.000
T92.0 Sequelae of open wound of upper limb
0.762 0.238 0.000
C90.2 Plasmacytoma, extramedullary
0.762 0.238 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.760 0.240 0.000
T23 Burn and corrosion of wrist and hand
0.760 0.240 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.760 0.240 0.000
O30 Multiple gestation
0.758 0.242 0.000
C77.1 Intrathoracic lymph nodes
0.757 0.243 0.000
S41 Open wound of shoulder and upper arm
0.756 0.244 0.000
C92 Myeloid leukaemia
0.756 0.244 0.000
T90 Sequelae of injuries of head
0.755 0.245 0.000
E16.2 Hypoglycaemia, unspecified
0.754 0.246 0.000
E29 Testicular dysfunction
0.754 0.246 0.000
E24.0 Pituitary-dependent Cushing's disease
0.753 0.247 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.753 0.247 0.000
S42.1 Fracture of scapula
0.752 0.248 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.751 0.249 0.000
D55-D59 Haemolytic anaemias
0.751 0.249 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.750 0.250 0.000
E24.2 Drug-induced Cushing's syndrome
0.750 0.250 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.748 0.252 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.747 0.253 0.000
T95 Sequelae of burns, corrosions and frostbite
0.745 0.255 0.000
O61 Failed induction of labour
0.745 0.255 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.744 0.256 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.744 0.256 0.000
E06.3 Autoimmune thyroiditis
0.743 0.257 0.000
F80 Specific developmental disorders of speech and language
0.741 0.259 0.000
T58 Toxic effect of carbon monoxide
0.741 0.259 0.000
E22 Hyperfunction of pituitary gland
0.740 0.260 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.739 0.260 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
C82.0 Small cleaved cell, follicular
0.738 0.262 0.000
D05.1 Intraductal carcinoma in situ
0.737 0.263 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.734 0.266 0.000
T20 Burn and corrosion of head and neck
0.734 0.266 0.000
A04 Other bacterial intestinal infections
0.732 0.268 0.000
V10-V19 Pedal cyclist injured in transport accident
0.731 0.269 0.000
D68 Other coagulation defects
0.730 0.270 0.000
C81.1 Nodular sclerosis
0.729 0.271 0.000
T31 Burns classified according to extent of body surface involved
0.720 0.280 0.000
O66 Other obstructed labour
0.719 0.281 0.000
O73 Retained placenta and membranes, without haemorrhage
0.719 0.281 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C95 Leukaemia of unspecified cell type
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.716 0.284 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.284 0.000
T56 Toxic effect of metals
0.715 0.285 0.000
E07 Other disorders of thyroid
0.714 0.286 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.714 0.286 0.000
E50-E64 Other nutritional deficiencies
0.713 0.286 0.000
C83.1 Small cleaved cell (diffuse)
0.712 0.288 0.000
T98 Sequelae of other and unspecified effects of external causes
0.711 0.289 0.000
T21.2 Burn of second degree of trunk
0.711 0.289 0.000
Q24 Other congenital malformations of heart
0.711 0.289 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.711 0.289 0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs
0.710 0.290 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.709 0.291 0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)
0.709 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.709 0.291 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.708 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.708 0.292 0.000
Q28 Other congenital malformations of circulatory system
0.708 0.292 0.000
C91.9 Lymphoid leukaemia, unspecified
0.707 0.293 0.000
S90 Superficial injury of ankle and foot
0.706 0.294 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.705 0.295 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.704 0.296 0.000
C85.0 Lymphosarcoma
0.704 0.296 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.704 0.296 0.000
E00 Congenital iodine-deficiency syndrome
0.704 0.296 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.704 0.296 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.704 0.296 0.000
W22 Striking against or struck by other objects
0.703 0.297 0.000
O72.3 Postpartum coagulation defects
0.703 0.297 0.000
T11 Other injuries of upper limb, level unspecified
0.701 0.299 0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.700 0.299 0.000
E05.8 Other thyrotoxicosis
0.700 0.300 0.000
E05.5 Thyroid crisis or storm
0.700 0.300 0.000
E05.4 Thyrotoxicosis factitia
0.700 0.300 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.700 0.300 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.700 0.300 0.000
O44 Placenta praevia
0.700 0.300 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.699 0.301 0.000
C82.6 Cutaneous follicle centre lymphoma
0.699 0.301 0.000
C82.5 Diffuse follicle centre lymphoma
0.699 0.301 0.000
C82.4 Follicular lymphoma grade IIIb
0.699 0.301 0.000
C82.3 Follicular lymphoma grade IIIa
0.699 0.301 0.000
C82.2 Large cell, follicular
0.699 0.301 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.304 0.000
S48 Traumatic amputation of shoulder and upper arm
0.693 0.307 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.693 0.307 0.000
S44 Injury of nerves at shoulder and upper arm level
0.693 0.307 0.000
S47 Crushing injury of shoulder and upper arm
0.693 0.307 0.000
O41 Other disorders of amniotic fluid and membranes
0.693 0.307 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.693 0.307 0.000
O33 Maternal care for known or suspected disproportion
0.693 0.307 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.692 0.308 0.000
C90.3 Solitary plasmacytoma
0.692 0.308 0.000
T09 Other injuries of spine and trunk, level unspecified
0.691 0.309 0.000
C91.1 Chronic lymphocytic leukaemia
0.691 0.309 0.000
T14.0 Superficial injury of unspecified body region
0.691 0.309 0.000
T25 Burn and corrosion of ankle and foot
0.691 0.309 0.000
E85 Amyloidosis
0.690 0.310 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.689 0.311 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.689 0.311 0.000
F80.1 Expressive language disorder
0.688 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.688 0.312 0.000
C91.4 Hairy-cell leukaemia
0.688 0.312 0.000
O31 Complications specific to multiple gestation
0.687 0.313 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.687 0.313 0.000
T63 Toxic effect of contact with venomous animals
0.687 0.313 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.686 0.314 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.686 0.314 0.000
A04.8 Other specified bacterial intestinal infections
0.685 0.315 0.000
O32.0 Maternal care for unstable lie
0.684 0.315 0.000
Q23.1 Congenital insufficiency of aortic valve
0.684 0.316 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.316 0.000
E32 Diseases of thymus
0.683 0.316 0.000
E31 Polyglandular dysfunction
0.683 0.316 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.316 0.000
E25 Adrenogenital disorders
0.683 0.316 0.000
E20 Hypoparathyroidism
0.683 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.683 0.317 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.683 0.317 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.682 0.318 0.000
C71.9 Brain, unspecified
0.681 0.319 0.000
O63.9 Long labour, unspecified
0.681 0.319 0.000
C83.3 Large cell (diffuse)
0.680 0.320 0.000
O32.2 Maternal care for transverse and oblique lie
0.679 0.321 0.000
E34 Other endocrine disorders
0.679 0.321 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
O71 Other obstetric trauma
0.679 0.321 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.679 0.321 0.000
D04 Carcinoma in situ of skin
0.678 0.321 0.000
O45 Premature separation of placenta [abruptio placentae]
0.678 0.322 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.678 0.322 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.678 0.322 0.000
S31 Open wound of abdomen, lower back and pelvis
0.677 0.323 0.000
D50-D53 Nutritional anaemias
0.677 0.323 0.000
F10.1 Harmful use
0.675 0.325 0.000
C83.0 Small cell (diffuse)
0.675 0.325 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
T36 Poisoning by systemic antibiotics
0.674 0.326 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.674 0.326 0.000
A15-A19 Tuberculosis
0.674 0.326 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.674 0.326 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.672 0.328 0.000
T65 Toxic effect of other and unspecified substances
0.671 0.329 0.000
T62 Toxic effect of other noxious substances eaten as food
0.671 0.329 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.671 0.329 0.000
T60 Toxic effect of pesticides
0.671 0.329 0.000
T57 Toxic effect of other inorganic substances
0.671 0.329 0.000
T54 Toxic effect of corrosive substances
0.671 0.329 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.671 0.329 0.000
T52 Toxic effect of organic solvents
0.671 0.329 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.671 0.329 0.000
T55 Toxic effect of soaps and detergents
0.671 0.329 0.000
O20 Haemorrhage in early pregnancy
0.671 0.329 0.000
S91.1 Open wound of toe(s) without damage to nail
0.670 0.330 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.670 0.330 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.669 0.331 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.668 0.332 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.668 0.332 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.667 0.332 0.000
F70-F79 Mental retardation
0.667 0.332 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.666 0.334 0.000
C88 Malignant immunoproliferative diseases
0.666 0.334 0.000
C77.4 Inguinal and lower limb lymph nodes
0.665 0.335 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.664 0.336 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.664 0.336 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.663 0.336 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.663 0.337 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.662 0.338 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.661 0.339 0.000
W50-W64 Exposure to animate mechanical forces
0.660 0.340 0.000
F10.3 Withdrawal state
0.660 0.340 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.660 0.340 0.000
B25-B34 Other viral diseases
0.660 0.340 0.000
S40 Superficial injury of shoulder and upper arm
0.660 0.340 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.660 0.340 0.000
Q35-Q37 Cleft lip and cleft palate
0.660 0.340 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.660 0.340 0.000
O34.1 Maternal care for tumour of corpus uteri
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
T40.6 Other and unspecified narcotics
0.659 0.341 0.000
S61 Open wound of wrist and hand
0.659 0.341 0.000
Y00-Y09 Assault
0.658 0.342 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.657 0.343 0.000
D09 Carcinoma in situ of other and unspecified sites
0.655 0.345 0.000
E89.0 Postprocedural hypothyroidism
0.655 0.345 0.000
S65 Injury of blood vessels at wrist and hand level
0.655 0.345 0.000
S91.3 Open wound of other parts of foot
0.655 0.345 0.000
V01-V09 Pedestrian injured in transport accident
0.655 0.345 0.000
S42.10 Fracture of scapula (closed)
0.654 0.346 0.000
A63.0 Anogenital (venereal) warts
0.654 0.346 0.000
E27.2 Addisonian crisis
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.653 0.346 0.000
E23 Hypofunction and other disorders of pituitary gland
0.653 0.346 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.653 0.347 0.000
O34.6 Maternal care for abnormality of vagina
0.653 0.347 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.653 0.347 0.000
O34.3 Maternal care for cervical incompetence
0.653 0.347 0.000
O34.0 Maternal care for congenital malformation of uterus
0.653 0.347 0.000
O32.4 Maternal care for high head at term
0.653 0.347 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.652 0.348 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.651 0.348 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.651 0.348 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.651 0.348 0.000
T42.3 Barbiturates
0.651 0.348 0.000
T42.2 Succinimides and oxazolidinediones
0.651 0.348 0.000
T42.0 Hydantoin derivatives
0.651 0.348 0.000
W75-W84 Other accidental threats to breathing
0.651 0.348 0.000
O34.4 Maternal care for other abnormalities of cervix
0.651 0.349 0.000
C69 Malignant neoplasm of eye and adnexa
0.650 0.350 0.000
T01 Open wounds involving multiple body regions
0.650 0.350 0.000
F10.5 Psychotic disorder
0.650 0.350 0.000
D58 Other hereditary haemolytic anaemias
0.650 0.350 0.000
E24.8 Other Cushing's syndrome
0.648 0.352 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.648 0.352 0.000
E24.3 Ectopic ACTH syndrome
0.648 0.352 0.000
E24.1 Nelson's syndrome
0.648 0.352 0.000
Q00-Q07 Congenital malformations of the nervous system
0.648 0.352 0.000
S67 Crushing injury of wrist and hand
0.648 0.352 0.000
S42.4 Fracture of lower end of humerus
0.648 0.352 0.000
T13 Other injuries of lower limb, level unspecified
0.647 0.352 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.647 0.352 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.647 0.352 0.000
T12 Fracture of lower limb, level unspecified
0.647 0.352 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.647 0.352 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.647 0.352 0.000
T10 Fracture of upper limb, level unspecified
0.647 0.352 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.647 0.352 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.647 0.352 0.000
T08 Fracture of spine, level unspecified
0.647 0.352 0.000
D66 Hereditary factor VIII deficiency
0.647 0.353 0.000
B35-B49 Mycoses
0.647 0.353 0.000
S60 Superficial injury of wrist and hand
0.647 0.353 0.000
W22.9 Unspecified place
0.647 0.353 0.000
S00-S09 Injuries to the head
0.647 0.353 0.000
D03 Melanoma in situ
0.646 0.354 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.645 0.355 0.000
Q21 Congenital malformations of cardiac septa
0.645 0.355 0.000
D68.5 Primary Thrombophilia
0.645 0.355 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.645 0.355 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.645 0.355 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.645 0.355 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.645 0.355 0.000
F11 Mental and behavioural disorders due to use of opioids
0.645 0.355 0.000
E26 Hyperaldosteronism
0.644 0.356 0.000
T90.9 Sequelae of unspecified injury of head
0.644 0.356 0.000
Chapter IX Diseases of the circulatory system
0.643 0.357 0.000
C92.7 Other myeloid leukaemia
0.643 0.357 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.643 0.357 0.000
T91 Sequelae of injuries of neck and trunk
0.642 0.358 0.000
E74 Other disorders of carbohydrate metabolism
0.642 0.358 0.000
C83.7 Burkitt's tumour
0.642 0.358 0.000
C83.6 Undifferentiated (diffuse)
0.642 0.358 0.000
C83.5 Lymphoblastic (diffuse)
0.642 0.358 0.000
C83.4 Immunoblastic (diffuse)
0.642 0.358 0.000
C83.2 Mixed small and large cell (diffuse)
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.641 0.358 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.641 0.359 0.000
S99 Other and unspecified injuries of ankle and foot
0.641 0.359 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.641 0.359 0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.640 0.359 0.000
O16 Unspecified maternal hypertension
0.640 0.360 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.640 0.360 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.640 0.360 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.640 0.360 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.640 0.360 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.640 0.360 0.000
T44.0 Anticholinesterase agents
0.640 0.360 0.000
B50-B64 Protozoal diseases
0.639 0.360 0.000
X10-X19 Contact with heat and hot substances
0.639 0.361 0.000
E27.1 Primary adrenocortical insufficiency
0.639 0.361 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.639 0.361 0.000
T00 Superficial injuries involving multiple body regions
0.638 0.362 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.638 0.362 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.637 0.363 0.000
T42.1 Iminostilbenes
0.637 0.363 0.000
E15 Nondiabetic hypoglycaemic coma
0.636 0.364 0.000
T31.0 Burns involving less than 10% of body surface
0.636 0.364 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.636 0.364 0.000
F50 Eating disorders
0.636 0.364 0.000
T14.1 Open wound of unspecified body region
0.635 0.364 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.635 0.365 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.634 0.366 0.000
F10.8 Other mental and behavioural disorders
0.633 0.366 0.000
F10.7 Residual and late-onset psychotic disorder
0.633 0.366 0.000
F10.6 Amnesic syndrome
0.633 0.366 0.000
S00 Superficial injury of head
0.633 0.367 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.632 0.367 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.632 0.368 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.632 0.368 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.631 0.369 0.000
C51-C58 Malignant neoplasms of female genital organs
0.631 0.369 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.631 0.369 0.000
D80-D89 Certain disorders involving the immune mechanism
0.630 0.370 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.630 0.370 0.000
C81.9 Hodgkin's disease, unspecified
0.630 0.370 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.630 0.370 0.000
E07.8 Other specified disorders of thyroid
0.629 0.370 0.000
V40-V49 Car occupant injured in transport accident
0.629 0.371 0.000
Q27 Other congenital malformations of peripheral vascular system
0.629 0.371 0.000
Q80-Q89 Other congenital malformations
0.628 0.371 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.627 0.373 0.000
X20-X29 Contact with venomous animals and plants
0.626 0.373 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.625 0.374 0.000
C70 Malignant neoplasm of meninges
0.625 0.374 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.625 0.375 0.000
D41.0 Kidney
0.625 0.375 0.000
Q26 Congenital malformations of great veins
0.624 0.376 0.000
Q25 Congenital malformations of great arteries
0.624 0.376 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.624 0.376 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.624 0.376 0.000
D68.2 Hereditary deficiency of other clotting factors
0.623 0.376 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.623 0.377 0.000
V20-V29 Motorcycle rider injured in transport accident
0.623 0.377 0.000
S43.1 Dislocation of acromioclavicular joint
0.623 0.377 0.000
T51.8 Other alcohols
0.623 0.377 0.000
T51.3 Fusel oil
0.623 0.377 0.000
T51.2 2-Propanol
0.623 0.377 0.000
T51.1 Methanol
0.623 0.377 0.000
C76.2 Abdomen
0.622 0.377 0.000
S98 Traumatic amputation of ankle and foot
0.622 0.377 0.000
S97 Crushing injury of ankle and foot
0.622 0.377 0.000
S95 Injury of blood vessels at ankle and foot level
0.622 0.377 0.000
S94 Injury of nerves at ankle and foot level
0.622 0.377 0.000
C76.3 Pelvis
0.622 0.378 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.622 0.378 0.000
O62 Abnormalities of forces of labour
0.621 0.378 0.000
F10.9 Unspecified mental and behavioural disorder
0.621 0.379 0.000
T59 Toxic effect of other gases, fumes and vapours
0.620 0.379 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.620 0.380 0.000
C91.7 Other lymphoid leukaemia
0.620 0.380 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.620 0.380 0.000
C91.5 Adult T-cell leukaemia
0.620 0.380 0.000
C91.3 Prolymphocytic leukaemia
0.620 0.380 0.000
C91.2 Subacute lymphocytic leukaemia
0.620 0.380 0.000
A65-A69 Other spirochaetal diseases
0.619 0.381 0.000
A02 Other Salmonella infections
0.619 0.381 0.000
O30.0 Twin pregnancy
0.615 0.385 0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb
0.615 0.385 0.000
T21.0 Burn of unspecified degree of trunk
0.613 0.387 0.000
S29 Other and unspecified injuries of thorax
0.612 0.388 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.611 0.389 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.611 0.389 0.000
W21 Striking against or struck by sports equipment
0.611 0.389 0.000
Y35-Y36 Legal intervention and operations of war
0.611 0.389 0.000
Y10-Y34 Event of undetermined intent
0.611 0.389 0.000
X85-X99 Assault
0.611 0.389 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.611 0.389 0.000
X30-X39 Exposure to forces of nature
0.611 0.389 0.000
X00-X09 Exposure to smoke, fire and flames
0.611 0.389 0.000
W65-W74 Accidental drowning and submersion
0.611 0.389 0.000
V98-V99 Other and unspecified transport accidents
0.611 0.389 0.000
V95-V97 Air and space transport accidents
0.611 0.389 0.000
V90-V94 Water transport accidents
0.611 0.389 0.000
V70-V79 Bus occupant injured in transport accident
0.611 0.389 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.611 0.389 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.611 0.389 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.611 0.389 0.000
E29.1 Testicular hypofunction
0.610 0.389 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.609 0.391 0.000
Q23.0 Congenital stenosis of aortic valve
0.609 0.391 0.000
E03 Other hypothyroidism
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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