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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61075980
log Bayes Factor = 27.6065
Chromosome 4   position 148,374,767  (GRCh37) Explore rs61075980 on Ensembl!
Variant rs61075980 is part of Cluster X0262

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20.0 Unstable angina
0.999 0.001 0.000
I20.8 Other forms of angina pectoris
0.998 0.002 0.000
I21 Acute myocardial infarction
0.987 0.013 0.000
I21.4 Acute subendocardial myocardial infarction
0.966 0.034 0.000
I22 Subsequent myocardial infarction
0.934 0.066 0.000
I25.5 Ischaemic cardiomyopathy
0.923 0.077 0.000
I10 Essential (primary) hypertension
0.889 0.111 0.000
I21.9 Acute myocardial infarction, unspecified
0.886 0.114 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.864 0.136 0.000
Z95.1 Presence of aortocoronary bypass graft
0.862 0.138 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.805 0.195 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.804 0.196 0.000
I22.8 Subsequent myocardial infarction of other sites
0.793 0.207 0.000
E78.0 Pure hypercholesterolaemia
0.787 0.213 0.000
I10-I15 Hypertensive diseases
0.782 0.218 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.780 0.220 0.000
I24 Other acute ischaemic heart diseases
0.770 0.230 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.708 0.292 0.000
Chapter IX Diseases of the circulatory system
0.694 0.306 0.000
I25.2 Old myocardial infarction
0.688 0.312 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.657 0.343 0.000
I23 Certain current complications following acute myocardial infarction
0.654 0.346 0.000
I15 Secondary hypertension
0.654 0.346 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.628 0.371 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.623 0.377 0.000
I25.3 Aneurysm of heart
0.615 0.385 0.000
I20.1 Angina pectoris with documented spasm
0.587 0.413 0.000
I24.1 Dressler's syndrome
0.581 0.419 0.000
I24.8 Other forms of acute ischaemic heart disease
0.579 0.421 0.000
I15.1 Hypertension secondary to other renal disorders
0.561 0.439 0.000
I13 Hypertensive heart and renal disease
0.561 0.439 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.550 0.450 0.000
I11 Hypertensive heart disease
0.548 0.452 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.538 0.462 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.502 0.497 0.000
I25.4 Coronary artery aneurysm
0.498 0.501 0.001
I00-I02 Acute rheumatic fever
0.497 0.502 0.000
I99 Other and unspecified disorders of circulatory system
0.497 0.503 0.000
I12 Hypertensive renal disease
0.471 0.529 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.469 0.531 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.469 0.531 0.000
I15.9 Seconday hypertension, unspecified
0.469 0.531 0.000
I15.8 Other secondary hypertension
0.469 0.531 0.000
I15.2 Hypertension secondary to endocrine disorders
0.469 0.531 0.000
I15.0 Renovascular hypertension
0.469 0.531 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.415 0.585 0.000
I23.8 Other current complications following acute myocardial infarction
0.405 0.594 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.402 0.598 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.402 0.598 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.402 0.598 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.402 0.598 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.360 0.640 0.000
I02 Rheumatic chorea
0.357 0.643 0.000
I01 Rheumatic fever with heart involvement
0.357 0.643 0.000
I00 Rheumatic fever without mention of heart involvement
0.357 0.643 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.352 0.648 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.350 0.650 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.347 0.653 0.000
I12.0 Hypertensive renal disease with renal failure
0.340 0.660 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.310 0.690 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.276 0.724 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.258 0.742 0.000
I97.0 Postcardiotomy syndrome
0.258 0.742 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.256 0.744 0.000
I01.8 Other acute rheumatic heart disease
0.256 0.744 0.000
I01.2 Acute rheumatic myocarditis
0.256 0.744 0.000
I01.1 Acute rheumatic endocarditis
0.256 0.744 0.000
I01.0 Acute rheumatic pericarditis
0.256 0.744 0.000
I02.9 Rheumatic chorea without heart involvement
0.256 0.744 0.000
I02.0 Rheumatic chorea with heart involvement
0.256 0.744 0.000
I95 Hypotension
0.256 0.744 0.000
I97.1 Other functional disturbances following cardiac surgery
0.254 0.746 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.254 0.746 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.251 0.749 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.251 0.749 0.000
I98.0 Cardiovascular syphilis
0.251 0.749 0.000
I12.9 Hypertensive renal disease without renal failure
0.245 0.755 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.244 0.756 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.237 0.763 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.221 0.779 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.221 0.779 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.211 0.789 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.211 0.789 0.000
I95.8 Other hypotension
0.211 0.789 0.000
I74 Arterial embolism and thrombosis
0.207 0.793 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.202 0.798 0.000
I95.2 Hypotension due to drugs
0.196 0.804 0.000
I05-I09 Chronic rheumatic heart diseases
0.193 0.806 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.192 0.808 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.184 0.816 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.182 0.818 0.000
I73 Other peripheral vascular diseases
0.182 0.818 0.000
I95.0 Idiopathic hypotension
0.172 0.828 0.000
I78 Diseases of capillaries
0.172 0.828 0.000
E78.4 Other hyperlipidaemia
0.168 0.832 0.000
I28 Other diseases of pulmonary vessels
0.164 0.836 0.000
I74.5 Embolism and thrombosis of iliac artery
0.162 0.838 0.000
E78.1 Pure hyperglyceridaemia
0.160 0.840 0.000
I95.1 Orthostatic hypotension
0.159 0.841 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.159 0.841 0.000
I70 Atherosclerosis
0.155 0.845 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.155 0.845 0.000
I74.8 Embolism and thrombosis of other arteries
0.152 0.848 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.150 0.850 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.149 0.851 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.149 0.851 0.000
I73.8 Other specified peripheral vascular diseases
0.146 0.854 0.000
E78.3 Hyperchylomicronaemia
0.145 0.855 0.000
I72 Other aneurysm
0.145 0.855 0.000
I73.9 Peripheral vascular disease, unspecified
0.144 0.856 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.143 0.857 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.143 0.857 0.000
E78.6 Lipoprotein deficiency
0.139 0.861 0.000
I06 Rheumatic aortic valve diseases
0.139 0.861 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.138 0.862 0.000
I79.1 Aortitis in diseases classified elsewhere
0.138 0.862 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.138 0.862 0.000
I09 Other rheumatic heart diseases
0.135 0.865 0.000
E78.5 Hyperlipidaemia, unspecified
0.129 0.871 0.000
E78.8 Other disorders of lipoprotein metabolism
0.127 0.873 0.000
I78.9 Disease of capillaries, unspecified
0.123 0.876 0.000
I70.1 Atherosclerosis of renal artery
0.122 0.878 0.000
I72.3 Aneurysm of iliac artery
0.121 0.878 0.000
Z95.0 Presence of cardiac pacemaker
0.120 0.880 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.117 0.882 0.000
I28.1 Aneurysm of pulmonary artery
0.117 0.882 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.117 0.882 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.117 0.883 0.000
I70.9 Generalised and unspecified atherosclerosis
0.111 0.888 0.000
I70.8 Atherosclerosis of other arteries
0.111 0.888 0.000
I28.8 Other specified diseases of pulmonary vessels
0.111 0.889 0.000
I78.8 Other diseases of capillaries
0.109 0.891 0.000
I78.1 Naevus, nonneoplastic
0.105 0.895 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.104 0.896 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.104 0.896 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.104 0.896 0.000
I72.2 Aneurysm of renal artery
0.104 0.896 0.000
I72.1 Aneurysm of artery of upper extremity
0.104 0.896 0.000
I07 Rheumatic tricuspid valve diseases
0.104 0.896 0.000
I26 Pulmonary embolism
0.102 0.898 0.000
Z95.3 Presence of xenogenic heart valve
0.101 0.899 0.000
I72.8 Aneurysm of other specified arteries
0.101 0.899 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.100 0.900 0.000
I06.8 Other rheumatic aortic valve diseases
0.100 0.900 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.100 0.900 0.000
I06.1 Rheumatic aortic insufficiency
0.100 0.900 0.000
I06.0 Rheumatic aortic stenosis
0.100 0.900 0.000
I70.0 Atherosclerosis of aorta
0.099 0.901 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.099 0.901 0.000
I72.9 Aneurysm of unspecified site
0.098 0.902 0.000
I05 Rheumatic mitral valve diseases
0.097 0.902 0.000
I09.8 Other specified rheumatic heart diseases
0.097 0.903 0.000
I09.2 Chronic rheumatic pericarditis
0.097 0.903 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.097 0.903 0.000
I09.0 Rheumatic myocarditis
0.097 0.903 0.000
I09.9 Rheumatic heart disease, unspecified
0.092 0.907 0.000
E78.2 Mixed hyperlipidaemia
0.092 0.908 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.089 0.910 0.000
I27 Other pulmonary heart diseases
0.088 0.911 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.088 0.912 0.000
I72.0 Aneurysm of carotid artery
0.085 0.915 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.084 0.916 0.000
I77 Other disorders of arteries and arterioles
0.081 0.919 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.080 0.920 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.080 0.920 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.080 0.920 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.080 0.920 0.000
I08 Multiple valve diseases
0.077 0.923 0.000
I72.4 Aneurysm of artery of lower extremity
0.077 0.923 0.000
I07.9 Tricuspid valve disease, unspecified
0.075 0.925 0.000
I07.8 Other tricuspid valve diseases
0.075 0.925 0.000
I07.2 Tricuspid stenosis with insufficiency
0.075 0.925 0.000
I07.0 Tricuspid stenosis
0.075 0.925 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.073 0.927 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.072 0.928 0.000
I05.9 Mitral valve disease, unspecified
0.071 0.929 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.071 0.929 0.000
I05.8 Other mitral valve diseases
0.070 0.930 0.000
I05.2 Mitral stenosis with insufficiency
0.067 0.933 0.000
Z95.4 Presence of other heart-valve replacement
0.066 0.934 0.000
I27.1 Kyphoscoliotic heart disease
0.063 0.936 0.000
I27.8 Other specified pulmonary heart diseases
0.063 0.936 0.000
I08.9 Multiple valve disease, unspecified
0.062 0.938 0.000
I27.0 Primary pulmonary hypertension
0.062 0.938 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.060 0.940 0.000
I05.1 Rheumatic mitral insufficiency
0.059 0.940 0.000
I77.0 Arteriovenous fistula, acquired
0.059 0.941 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.058 0.941 0.000
I77.5 Necrosis of artery
0.058 0.942 0.000
I77.4 Coeliac artery compression syndrome
0.058 0.942 0.000
I77.3 Arterial fibromuscular dysplasia
0.058 0.942 0.000
I77.2 Rupture of artery
0.058 0.942 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.056 0.944 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.056 0.944 0.000
I71 Aortic aneurysm and dissection
0.054 0.946 0.000
I77.8 Other specified disorders of arteries and arterioles
0.054 0.946 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.054 0.946 0.000
I05.0 Mitral stenosis
0.051 0.949 0.000
I73.0 Raynaud's syndrome
0.046 0.954 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.044 0.956 0.000
I27.9 Pulmonary heart disease, unspecified
0.041 0.958 0.000
Z95.2 Presence of prosthetic heart valve
0.041 0.958 0.000
I07.1 Tricuspid insufficiency
0.039 0.960 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.039 0.961 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.039 0.961 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.039 0.961 0.000
I77.1 Stricture of artery
0.038 0.962 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.036 0.964 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.035 0.965 0.000
I08.8 Other multiple valve diseases
0.035 0.965 0.000
I27.2 Other secondary pulmonary hypertension
0.035 0.965 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.032 0.968 0.000
I71.0 Dissection of aorta [any part]
0.028 0.972 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.023 0.977 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.022 0.977 0.001
I77.6 Arteritis, unspecified
0.020 0.979 0.001
K86.8 Other specified diseases of pancreas
0.000 0.980 0.020
K86 Other diseases of pancreas
0.000 0.982 0.018
E70-E90 Metabolic disorders
0.017 0.983 0.000
K86.1 Other chronic pancreatitis
0.000 0.983 0.017
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.016 0.984 0.001
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.984 0.016
I08.0 Disorders of both mitral and aortic valves
0.015 0.985 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.015 0.985 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.985 0.015
K86.3 Pseudocyst of pancreas
0.000 0.985 0.015
E88 Other metabolic disorders
0.015 0.985 0.000
E89.3 Postprocedural hypopituitarism
0.014 0.986 0.000
E89.2 Postprocedural hypoparathyroidism
0.013 0.986 0.000
K86.2 Cyst of pancreas
0.000 0.987 0.013
E80 Disorders of porphyrin and bilirubin metabolism
0.013 0.987 0.000
K86.9 Disease of pancreas, unspecified
0.000 0.987 0.013
E74 Other disorders of carbohydrate metabolism
0.013 0.987 0.000
E84 Cystic fibrosis
0.013 0.987 0.000
E79 Disorders of purine and pyrimidine metabolism
0.013 0.987 0.000
E77 Disorders of glycoprotein metabolism
0.013 0.987 0.000
E76 Disorders of glycosaminoglycan metabolism
0.013 0.987 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.013 0.987 0.000
E72 Other disorders of amino-acid metabolism
0.013 0.987 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.013 0.987 0.000
E70 Disorders of aromatic amino-acid metabolism
0.013 0.987 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.013 0.987 0.000
E88.3 Tumour lysis syndrome
0.012 0.987 0.000
N92 Excessive, frequent and irregular menstruation
0.013 0.987 0.000
E85 Amyloidosis
0.012 0.988 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.012 0.988 0.000
M94.88 Other specified disorders of cartilage (Other)
0.000 0.989 0.011
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.011 0.989 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.011 0.989 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.011 0.989 0.000
E89.5 Postprocedural testicular hypofunction
0.011 0.989 0.000
E89.4 Postprocedural ovarian failure
0.011 0.989 0.000
E89.1 Postprocedural hypoinsulinaemia
0.011 0.989 0.000
E73 Lactose intolerance
0.011 0.989 0.000
E88.9 Metabolic disorder, unspecified
0.011 0.989 0.000
E88.8 Other specified metabolic disorders
0.011 0.989 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.011 0.989 0.000
E88.2 Lipomatosis, not elsewhere classified
0.010 0.989 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.000 0.989 0.011
M94.8 Other specified disorders of cartilage
0.000 0.990 0.010
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.990 0.010
I60 Subarachnoid haemorrhage
0.000 0.990 0.010
N92.5 Other specified irregular menstruation
0.010 0.990 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.010 0.990 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.990 0.010
E80.6 Other disorders of bilirubin metabolism
0.010 0.990 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.009 0.990 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.009 0.990 0.000
E80.5 Crigler-Najjar syndrome
0.009 0.990 0.000
E80.3 Defects of catalase and peroxydase
0.009 0.990 0.000
E80.2 Other porphyria
0.009 0.990 0.000
E80.1 Porphyria cutanea tarda
0.009 0.990 0.000
E80.0 Hereditary erythropoietic porphyria
0.009 0.990 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.009 0.991 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.009 0.991 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.009 0.991 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.009 0.991 0.000
E74.2 Disorders of galactose metabolism
0.009 0.991 0.000
E74.1 Disorders of fructose metabolism
0.009 0.991 0.000
E74.0 Glycogen storage disease
0.009 0.991 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.009 0.991 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.009 0.991 0.000
E70.3 Albinism
0.009 0.991 0.000
E70.2 Disorders of tyrosine metabolism
0.009 0.991 0.000
E70.1 Other hyperphenylalaninaemias
0.009 0.991 0.000
E70.0 Classical phenylketonuria
0.009 0.991 0.000
E71.3 Disorders of fatty-acid metabolism
0.009 0.991 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.009 0.991 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.009 0.991 0.000
E71.0 Maple-syrup-urine disease
0.009 0.991 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.009 0.991 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.009 0.991 0.000
E72.5 Disorders of glycine metabolism
0.009 0.991 0.000
E72.4 Disorders of ornithine metabolism
0.009 0.991 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.009 0.991 0.000
E72.2 Disorders of urea cycle metabolism
0.009 0.991 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.009 0.991 0.000
E72.0 Disorders of amino-acid transport
0.009 0.991 0.000
E75.6 Lipid storage disorder, unspecified
0.009 0.991 0.000
E75.5 Other lipid storage disorders
0.009 0.991 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.009 0.991 0.000
E75.3 Sphingolipidosis, unspecified
0.009 0.991 0.000
E75.2 Other sphingolipidosis
0.009 0.991 0.000
E75.1 Other gangliosidosis
0.009 0.991 0.000
E75.0 GM2 gangliosidosis
0.009 0.991 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.009 0.991 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.009 0.991 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.009 0.991 0.000
E76.2 Other mucopolysaccharidoses
0.009 0.991 0.000
E76.1 Mucopolysaccharidosis, type II
0.009 0.991 0.000
E76.0 Mucopolysaccharidosis, type I
0.009 0.991 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.009 0.991 0.000
E77.8 Other disorders of glycoprotein metabolism
0.009 0.991 0.000
E77.1 Defects in glycoprotein degradation
0.009 0.991 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.009 0.991 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.009 0.991 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.009 0.991 0.000
E79.1 Lesch-Nyhan syndrome
0.009 0.991 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.009 0.991 0.000
E84.9 Cystic fibrosis, unspecified
0.009 0.991 0.000
E84.8 Cystic fibrosis with other manifestations
0.009 0.991 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.009 0.991 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.009 0.991 0.000
E85.4 Organ-limited amyloidosis
0.009 0.991 0.000
E89.0 Postprocedural hypothyroidism
0.009 0.991 0.000
N92.2 Excessive menstruation at puberty
0.009 0.991 0.000
E80.4 Gilbert's syndrome
0.009 0.991 0.000
E85.8 Other amyloidosis
0.009 0.991 0.000
E85.3 Secondary systemic amyloidosis
0.009 0.991 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.009 0.991 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.009 0.991 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.009 0.991 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.991 0.009
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.991 0.008
I88 Nonspecific lymphadenitis
0.008 0.992 0.000
E73.8 Other lactose intolerance
0.008 0.992 0.000
E73.1 Secondary lactase deficiency
0.008 0.992 0.000
E73.0 Congenital lactase deficiency
0.008 0.992 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.992 0.008
M94.89 Other specified disorders of cartilage (Site unspecified)
0.000 0.992 0.008
I60.8 Other subarachnoid haemorrhage
0.000 0.992 0.008
M94.87 Other specified disorders of cartilage (Ankle and foot)
0.000 0.992 0.008
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.000 0.992 0.008
M94.84 Other specified disorders of cartilage (Hand)
0.000 0.992 0.008
M94.83 Other specified disorders of cartilage (Forearm)
0.000 0.992 0.008
M94.82 Other specified disorders of cartilage (Upper arm)
0.000 0.992 0.008
M94.81 Other specified disorders of cartilage (Shoulder region)
0.000 0.992 0.008
M94.80 Other specified disorders of cartilage (Multiple sites)
0.000 0.992 0.008
I60-I69 Cerebrovascular diseases
0.004 0.992 0.004
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.992 0.007
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.992 0.007
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.992 0.007
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.992 0.007
E85.9 Amyloidosis, unspecified
0.007 0.992 0.000
I85 Oesophageal varices
0.007 0.993 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.007 0.993 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.007 0.993 0.000
N92.4 Excessive bleeding in the premenopausal period
0.007 0.993 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.007 0.993 0.000
E73.9 Lactose intolerance, unspecified
0.006 0.993 0.000
I88.8 Other nonspecific lymphadenitis
0.006 0.994 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.006 0.994 0.000
I85.0 Oesophageal varices with bleeding
0.006 0.994 0.000
I81 Portal vein thrombosis
0.006 0.994 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.006 0.994 0.000
I89.1 Lymphangitis
0.006 0.994 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.003 0.994 0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.003 0.994 0.003
N92.3 Ovulation bleeding
0.006 0.994 0.000
M94 Other disorders of cartilage
0.000 0.994 0.005
G40.9 Epilepsy, unspecified
0.000 0.995 0.005
I62 Other nontraumatic intracranial haemorrhage
0.001 0.995 0.004
I85.9 Oesophageal varices without bleeding
0.005 0.995 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.003 0.995 0.002
I95.9 Hypotension, unspecified
0.005 0.995 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.005 0.995 0.000
E65 Localised adiposity
0.005 0.995 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.995 0.005
I82 Other venous embolism and thrombosis
0.005 0.995 0.000
M94.9 Disorder of cartilage, unspecified
0.000 0.995 0.005
E83 Disorders of mineral metabolism
0.005 0.995 0.000
I61 Intracerebral haemorrhage
0.001 0.995 0.004
I69 Sequelae of cerebrovascular disease
0.000 0.996 0.004
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.002 0.996 0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.002 0.996 0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.002 0.996 0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.996 0.004
I66.8 Occlusion and stenosis of other cerebral artery
0.002 0.996 0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.002 0.996 0.002
I66.3 Occlusion and stenosis of cerebellar arteries
0.002 0.996 0.002
I66.2 Occlusion and stenosis of posterior cerebral artery
0.002 0.996 0.002
I66.1 Occlusion and stenosis of anterior cerebral artery
0.002 0.996 0.002
I66.0 Occlusion and stenosis of middle cerebral artery
0.002 0.996 0.002
I87 Other disorders of veins
0.004 0.996 0.000
I86 Varicose veins of other sites
0.004 0.996 0.000
I68.0 Cerebral amyloid angiopathy
0.002 0.996 0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.002 0.996 0.002
M94.3 Chondrolysis
0.000 0.996 0.004
M94.1 Relapsing polychondritis
0.000 0.996 0.004
M94.0 Chondrocostal junction syndrome [Tietze]
0.000 0.996 0.004
H60.1 Cellulitis of external ear
0.004 0.996 0.000
I82.2 Embolism and thrombosis of vena cava
0.004 0.996 0.000
E65-E68 Obesity and other hyperalimentation
0.004 0.996 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.004 0.996 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.004 0.996 0.000
I62.1 Nontraumatic extradural haemorrhage
0.001 0.996 0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.996 0.004
N92.6 Irregular menstruation, unspecified
0.004 0.996 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.002 0.996 0.002
I65.8 Occlusion and stenosis of other precerebral artery
0.002 0.996 0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.002 0.996 0.002
I65.1 Occlusion and stenosis of basilar artery
0.002 0.996 0.002
M94.96 Disorder of cartilage, unspecified (Lower leg)
0.000 0.996 0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.996 0.004
I82.3 Embolism and thrombosis of renal vein
0.004 0.996 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.996 0.004
H60.9 Otitis externa, unspecified
0.004 0.996 0.000
I82.1 Thrombophlebitis migrans
0.004 0.996 0.000
I82.0 Budd-Chiari syndrome
0.004 0.996 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.002 0.996 0.002
H60 Otitis externa
0.004 0.996 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.996 0.003
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.996 0.003
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.996 0.004
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.996 0.003
E87.5 Hyperkalaemia
0.004 0.996 0.000
E50-E64 Other nutritional deficiencies
0.004 0.996 0.000
M94.2 Chondromalacia
0.000 0.996 0.003
G40 Epilepsy
0.000 0.996 0.004
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.996 0.003
M94.99 Disorder of cartilage, unspecified (Site unspecified)
0.000 0.996 0.003
M94.98 Disorder of cartilage, unspecified (Other)
0.000 0.996 0.003
M94.97 Disorder of cartilage, unspecified (Ankle and foot)
0.000 0.996 0.003
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)
0.000 0.996 0.003
M94.94 Disorder of cartilage, unspecified (Hand)
0.000 0.996 0.003
M94.93 Disorder of cartilage, unspecified (Forearm)
0.000 0.996 0.003
M94.92 Disorder of cartilage, unspecified (Upper arm)
0.000 0.996 0.003
M94.91 Disorder of cartilage, unspecified (Shoulder region)
0.000 0.996 0.003
M94.90 Disorder of cartilage, unspecified (Multiple sites)
0.000 0.996 0.003
E83.9 Disorder of mineral metabolism, unspecified
0.003 0.996 0.000
E83.8 Other disorders of mineral metabolism
0.003 0.996 0.000
E83.2 Disorders of zinc metabolism
0.003 0.996 0.000
E83.0 Disorders of copper metabolism
0.003 0.996 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.996 0.003
I61.8 Other intracerebral haemorrhage
0.001 0.996 0.003
K05.1 Chronic gingivitis
0.004 0.996 0.000
S09.9 Unspecified injury of head
0.000 0.996 0.003
G40.8 Other epilepsy
0.000 0.997 0.003
E83.4 Disorders of magnesium metabolism
0.003 0.997 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.997 0.003
I87.9 Disorder of vein, unspecified
0.003 0.997 0.000
I87.0 Postphlebitic syndrome
0.003 0.997 0.000
I86.3 Vulval varices
0.003 0.997 0.000
I86.0 Sublingual varices
0.003 0.997 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.003 0.997 0.000
I86.2 Pelvic varices
0.003 0.997 0.000
I65.2 Occlusion and stenosis of carotid artery
0.003 0.997 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.003 0.997 0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec
0.000 0.997 0.003
M94.08 Chondrocostal junction syndrome [Tietze]-Other
0.000 0.997 0.003
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot
0.000 0.997 0.003
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg
0.000 0.997 0.003
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh
0.000 0.997 0.003
M94.04 Chondrocostal junction syndrome [Tietze]-Hand
0.000 0.997 0.003
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm
0.000 0.997 0.003
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm
0.000 0.997 0.003
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region
0.000 0.997 0.003
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites
0.000 0.997 0.003
M94.19 Relapsing polychondritis (Site unspecified)
0.000 0.997 0.003
M94.18 Relapsing polychondritis (Other)
0.000 0.997 0.003
M94.17 Relapsing polychondritis (Ankle and foot)
0.000 0.997 0.003
M94.16 Relapsing polychondritis (Lower leg)
0.000 0.997 0.003
M94.15 Relapsing polychondritis (Pelvic region and thigh)
0.000 0.997 0.003
M94.14 Relapsing polychondritis (Hand)
0.000 0.997 0.003
M94.13 Relapsing polychondritis (Forearm)
0.000 0.997 0.003
M94.12 Relapsing polychondritis (Upper arm)
0.000 0.997 0.003
M94.11 Relapsing polychondritis (Shoulder region)
0.000 0.997 0.003
M94.10 Relapsing polychondritis (Multiple sites)
0.000 0.997 0.003
M94.39 Chondrolysis (Site unspecified)
0.000 0.997 0.003
M94.38 Chondrolysis (Other)
0.000 0.997 0.003
M94.37 Chondrolysis (Ankle and foot)
0.000 0.997 0.003
M94.36 Chondrolysis (Lower leg)
0.000 0.997 0.003
M94.35 Chondrolysis (Pelvic region and thigh)
0.000 0.997 0.003
M94.34 Chondrolysis (Hand)
0.000 0.997 0.003
M94.33 Chondrolysis (Forearm)
0.000 0.997 0.003
M94.32 Chondrolysis (Upper arm)
0.000 0.997 0.003
M94.31 Chondrolysis (Shoulder region)
0.000 0.997 0.003
M94.30 Chondrolysis (Multiple sites)
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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