TreeWAS – Variant ID: rs6110969

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.000	0.828	0.172
I49 Other cardiac arrhythmias	0.000	0.832	0.168
I44 Atrioventricular and left bundle-branch block	0.000	0.835	0.165
I47 Paroxysmal tachycardia	0.000	0.835	0.165
I34 Nonrheumatic mitral valve disorders	0.000	0.837	0.163
I49.9 Cardiac arrhythmia, unspecified	0.000	0.839	0.161
I49.4 Other and unspecified premature depolarisation	0.000	0.840	0.160
I44.1 Atrioventricular block, second degree	0.000	0.842	0.158
I34.0 Mitral (valve) insufficiency	0.000	0.843	0.157
I45 Other conduction disorders	0.000	0.847	0.153
I44.7 Left bundle-branch block, unspecified	0.000	0.851	0.149
I37 Pulmonary valve disorders	0.000	0.857	0.143
I31 Other diseases of pericardium	0.000	0.857	0.143
I49.5 Sick sinus syndrome	0.000	0.858	0.142
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.858	0.142
I47.2 Ventricular tachycardia	0.000	0.859	0.141
I47.1 Supraventricular tachycardia	0.000	0.860	0.140
I46 Cardiac arrest	0.000	0.863	0.137
I31.9 Disease of pericardium, unspecified	0.000	0.867	0.133
I44.6 Other and unspecified fascicular block	0.000	0.867	0.132
I45.5 Other specified heart block	0.000	0.868	0.132
I33 Acute and subacute endocarditis	0.000	0.870	0.130
I45.9 Conduction disorder, unspecified	0.000	0.870	0.130
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.875	0.125
I47.0 Reentry ventricular arrhythmia	0.000	0.876	0.124
I30 Acute pericarditis	0.000	0.876	0.124
I52 Other heart disorders in diseases classified elsewhere	0.000	0.877	0.123
I48 Atrial fibrillation and flutter	0.000	0.877	0.123
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.877	0.123
I41 Myocarditis in diseases classified elsewhere	0.000	0.877	0.123
I40 Acute myocarditis	0.000	0.877	0.123
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.877	0.123
I32 Pericarditis in diseases classified elsewhere	0.000	0.877	0.123
I37.1 Pulmonary valve insufficiency	0.000	0.877	0.123
I42 Cardiomyopathy	0.000	0.878	0.122
I44.3 Other and unspecified atrioventricular block	0.000	0.878	0.122
I49.2 Junctional premature depolarisation	0.000	0.880	0.120
I45.6 Preexcitation syndrome	0.000	0.881	0.119
I44.5 Left posterior fascicular block	0.000	0.881	0.118
I44.4 Left anterior fascicular block	0.000	0.881	0.118
I45.3 Trifascicular block	0.000	0.882	0.118
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.883	0.117
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.888	0.112
I45.8 Other specified conduction disorders	0.000	0.888	0.112
I45.4 Nonspecific intraventricular block	0.000	0.889	0.111
I45.0 Right fascicular block	0.000	0.890	0.110
I36 Nonrheumatic tricuspid valve disorders	0.000	0.891	0.109
I49.3 Ventricular premature depolarisation	0.000	0.891	0.109
I46.0 Cardiac arrest with successful resuscitation	0.000	0.891	0.109
I51 Complications and ill-defined descriptions of heart disease	0.000	0.892	0.108
I42.9 Cardiomyopathy, unspecified	0.000	0.894	0.106
I49.8 Other specified cardiac arrhythmias	0.000	0.895	0.105
I34.1 Mitral (valve) prolapse	0.000	0.896	0.104
I51.8 Other ill-defined heart diseases	0.000	0.897	0.103
I37.9 Pulmonary valve disorder, unspecified	0.000	0.897	0.103
I37.8 Other pulmonary valve disorders	0.000	0.897	0.103
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.897	0.103
I37.0 Pulmonary valve stenosis	0.000	0.897	0.103
I31.8 Other specified diseases of pericardium	0.000	0.897	0.103
I31.2 Haemopericardium, not elsewhere classified	0.000	0.897	0.103
I31.1 Chronic constrictive pericarditis	0.000	0.897	0.103
I46.9 Cardiac arrest, unspecified	0.000	0.897	0.103
I33.0 Acute and subacute infective endocarditis	0.000	0.899	0.101
I46.1 Sudden cardiac death, so described	0.000	0.901	0.098
I49.0 Ventricular fibrillation and flutter	0.000	0.902	0.098
I44.0 Atrioventricular block, first degree	0.000	0.903	0.097
I45.2 Bifascicular block	0.000	0.906	0.094
I33.9 Acute endocarditis, unspecified	0.000	0.906	0.094
I45.1 Other and unspecified right bundle-branch block	0.000	0.907	0.093
I42.8 Other cardiomyopathies	0.000	0.908	0.092
I50 Heart failure	0.000	0.909	0.091
I31.0 Chronic adhesive pericarditis	0.000	0.911	0.089
I30.9 Acute pericarditis, unspecified	0.000	0.911	0.089
I30.8 Other forms of acute pericarditis	0.000	0.911	0.089
I30.1 Infective pericarditis	0.000	0.911	0.089
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.911	0.089
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.911	0.089
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.911	0.089
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.911	0.089
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.911	0.089
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.911	0.089
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.911	0.089
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.911	0.089
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.911	0.089
I40.9 Acute myocarditis, unspecified	0.000	0.911	0.089
I40.8 Other acute myocarditis	0.000	0.911	0.089
I40.1 Isolated myocarditis	0.000	0.911	0.089
I40.0 Infective myocarditis	0.000	0.911	0.089
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.911	0.089
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.911	0.089
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.911	0.089
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.911	0.089
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.911	0.089
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.911	0.089
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.911	0.089
I48.4 Atypical atrial flutter	0.000	0.911	0.089
I48.3 Typical atrial flutter	0.000	0.911	0.089
I48.2 Chronic atrial fibrillation	0.000	0.911	0.089
I48.1 Persistent atrial fibrillation	0.000	0.911	0.089
I48.0 Paroxysmal atrial fibrillation	0.000	0.911	0.089
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.911	0.089
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.911	0.089
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.912	0.088
I42.5 Other restrictive cardiomyopathy	0.000	0.912	0.088
I42.4 Endocardial fibroelastosis	0.000	0.912	0.088
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.912	0.088
I51.4 Myocarditis, unspecified	0.000	0.912	0.088
I38 Endocarditis, valve unspecified	0.000	0.914	0.086
I42.6 Alcoholic cardiomyopathy	0.000	0.915	0.085
I31.3 Pericardial effusion (noninflammatory)	0.000	0.915	0.085
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.919	0.080
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.921	0.078
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.921	0.078
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.921	0.078
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.921	0.078
I51.5 Myocardial degeneration	0.000	0.922	0.078
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.922	0.078
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.922	0.078
I42.0 Dilated cardiomyopathy	0.000	0.923	0.077
I50.1 Left ventricular failure	0.000	0.924	0.076
I51.0 Cardiac septal defect, acquired	0.000	0.925	0.075
I51.6 Cardiovascular disease, unspecified	0.000	0.927	0.073
I42.2 Other hypertrophic cardiomyopathy	0.000	0.928	0.072
I44.2 Atrioventricular block, complete	0.000	0.931	0.069
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.935	0.064
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.935	0.064
I49.1 Atrial premature depolarisation	0.001	0.937	0.062
I50.0 Congestive heart failure	0.000	0.952	0.048
D70 Agranulocytosis	0.000	0.965	0.035
I51.9 Heart disease, unspecified	0.000	0.966	0.034
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.967	0.033
I08 Multiple valve diseases	0.000	0.968	0.032
I05-I09 Chronic rheumatic heart diseases	0.000	0.968	0.032
Chapter IX Diseases of the circulatory system	0.000	0.969	0.031
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.969	0.031
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.970	0.030
I50.9 Heart failure, unspecified	0.000	0.970	0.030
O26.8 Other specified pregnancy-related conditions	0.000	0.970	0.030
I82 Other venous embolism and thrombosis	0.000	0.971	0.029
I51.7 Cardiomegaly	0.000	0.972	0.028
I80 Phlebitis and thrombophlebitis	0.000	0.972	0.028
I82.8 Embolism and thrombosis of other specified veins	0.000	0.972	0.028
I81 Portal vein thrombosis	0.000	0.973	0.027
I07 Rheumatic tricuspid valve diseases	0.000	0.973	0.027
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.974	0.026
I87 Other disorders of veins	0.000	0.974	0.026
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.975	0.025
I86 Varicose veins of other sites	0.000	0.975	0.025
I05 Rheumatic mitral valve diseases	0.000	0.975	0.025
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.976	0.024
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.976	0.023
I08.9 Multiple valve disease, unspecified	0.000	0.977	0.023
I88 Nonspecific lymphadenitis	0.000	0.977	0.023
I06 Rheumatic aortic valve diseases	0.000	0.977	0.023
I86.1 Scrotal varices	0.000	0.977	0.023
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.977	0.023
I07.1 Tricuspid insufficiency	0.000	0.977	0.023
I09 Other rheumatic heart diseases	0.000	0.977	0.023
I00-I02 Acute rheumatic fever	0.000	0.978	0.022
I87.8 Other specified disorders of veins	0.000	0.979	0.021
I82.3 Embolism and thrombosis of renal vein	0.000	0.979	0.021
I82.1 Thrombophlebitis migrans	0.000	0.979	0.021
I82.0 Budd-Chiari syndrome	0.000	0.979	0.021
I82.2 Embolism and thrombosis of vena cava	0.000	0.979	0.021
I08.8 Other multiple valve diseases	0.000	0.979	0.021
I87.1 Compression of vein	0.000	0.979	0.020
I85 Oesophageal varices	0.000	0.980	0.020
I05.1 Rheumatic mitral insufficiency	0.000	0.980	0.019
I05.9 Mitral valve disease, unspecified	0.000	0.981	0.019
I07.9 Tricuspid valve disease, unspecified	0.000	0.981	0.019
I07.8 Other tricuspid valve diseases	0.000	0.981	0.019
I07.2 Tricuspid stenosis with insufficiency	0.000	0.981	0.019
I07.0 Tricuspid stenosis	0.000	0.981	0.019
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.981	0.019
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.981	0.019
I87.9 Disorder of vein, unspecified	0.000	0.981	0.019
I87.0 Postphlebitic syndrome	0.000	0.981	0.019
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.981	0.018
I05.2 Mitral stenosis with insufficiency	0.000	0.982	0.018
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.982	0.018
I86.3 Vulval varices	0.000	0.982	0.018
I86.2 Pelvic varices	0.000	0.982	0.018
I86.0 Sublingual varices	0.000	0.982	0.018
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.982	0.018
I05.8 Other mitral valve diseases	0.000	0.982	0.018
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.982	0.018
I89.0 Lymphoedema, not elsewhere classified	0.000	0.983	0.017
I08.0 Disorders of both mitral and aortic valves	0.000	0.983	0.017
I88.8 Other nonspecific lymphadenitis	0.000	0.983	0.017
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.983	0.017
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.983	0.017
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.983	0.017
I06.8 Other rheumatic aortic valve diseases	0.000	0.983	0.017
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.983	0.017
I06.1 Rheumatic aortic insufficiency	0.000	0.983	0.017
I06.0 Rheumatic aortic stenosis	0.000	0.983	0.017
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.983	0.017
I09.8 Other specified rheumatic heart diseases	0.000	0.983	0.016
I09.2 Chronic rheumatic pericarditis	0.000	0.983	0.016
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.983	0.016
I09.0 Rheumatic myocarditis	0.000	0.983	0.016
I86.8 Varicose veins of other specified sites	0.000	0.984	0.016
I89.1 Lymphangitis	0.000	0.984	0.016
I02 Rheumatic chorea	0.000	0.984	0.016
I01 Rheumatic fever with heart involvement	0.000	0.984	0.016
I00 Rheumatic fever without mention of heart involvement	0.000	0.984	0.016
I05.0 Mitral stenosis	0.000	0.984	0.016
I09.9 Rheumatic heart disease, unspecified	0.000	0.984	0.016
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.984	0.016
I85.0 Oesophageal varices with bleeding	0.000	0.985	0.015
I83 Varicose veins of lower extremities	0.000	0.985	0.015
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.986	0.014
I86.4 Gastric varices	0.000	0.986	0.014
I99 Other and unspecified disorders of circulatory system	0.000	0.986	0.014
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.986	0.014
I35 Nonrheumatic aortic valve disorders	0.000	0.987	0.013
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.987	0.013
Y43.3 Other antineoplastic drugs	0.000	0.987	0.013
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.987	0.013
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.988	0.012
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.988	0.012
I01.8 Other acute rheumatic heart disease	0.000	0.988	0.012
I01.2 Acute rheumatic myocarditis	0.000	0.988	0.012
I01.1 Acute rheumatic endocarditis	0.000	0.988	0.012
I01.0 Acute rheumatic pericarditis	0.000	0.988	0.012
I02.9 Rheumatic chorea without heart involvement	0.000	0.988	0.012
I02.0 Rheumatic chorea with heart involvement	0.000	0.988	0.012
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.988	0.012
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.989	0.011
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O26.5 Maternal hypotension syndrome	0.000	0.990	0.010
O26.4 Herpes gestationis	0.000	0.990	0.010
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.990	0.010
O26.1 Low weight gain in pregnancy	0.000	0.990	0.010
O26.0 Excessive weight gain in pregnancy	0.000	0.990	0.010
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.990	0.010
I85.9 Oesophageal varices without bleeding	0.000	0.990	0.010
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.990	0.010
I28 Other diseases of pulmonary vessels	0.000	0.990	0.010
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.990	0.009
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.990	0.009
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
I98.0 Cardiovascular syphilis	0.000	0.990	0.009
O26.2 Pregnancy care of habitual aborter	0.000	0.991	0.009
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.991	0.009
I35.8 Other aortic valve disorders	0.000	0.991	0.009
O26.9 Pregnancy-related condition, unspecified	0.000	0.991	0.009
I10-I15 Hypertensive diseases	0.000	0.992	0.008
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
I60-I69 Cerebrovascular diseases	0.000	0.992	0.008
N35.9 Urethral stricture, unspecified	0.000	0.992	0.008
I69 Sequelae of cerebrovascular disease	0.000	0.992	0.008
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.993	0.007
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.993	0.007
I28.8 Other specified diseases of pulmonary vessels	0.000	0.993	0.007
I28.1 Aneurysm of pulmonary artery	0.000	0.993	0.007
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.993	0.007
I35.9 Aortic valve disorder, unspecified	0.000	0.993	0.007
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.993	0.007
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.993	0.007
I97.0 Postcardiotomy syndrome	0.000	0.993	0.007
I69.3 Sequelae of cerebral infarction	0.000	0.993	0.007
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.993	0.007
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.993	0.007
I62 Other nontraumatic intracranial haemorrhage	0.000	0.993	0.007
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.993	0.006
I26 Pulmonary embolism	0.000	0.993	0.007
O24 Diabetes mellitus in pregnancy	0.000	0.993	0.006
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.994	0.006
I13 Hypertensive heart and renal disease	0.000	0.994	0.006
D74 Methaemoglobinaemia	0.000	0.994	0.006
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.994	0.006
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.994	0.006
I27 Other pulmonary heart diseases	0.000	0.994	0.006
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.994	0.006
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.994	0.006
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.994	0.006
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.994	0.006
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.994	0.006
I60 Subarachnoid haemorrhage	0.000	0.994	0.006
I15 Secondary hypertension	0.000	0.994	0.006
C91.1 Chronic lymphocytic leukaemia	0.006	0.994	0.000
I11 Hypertensive heart disease	0.000	0.994	0.006
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.994	0.006
D75 Other diseases of blood and blood-forming organs	0.000	0.994	0.006
O21 Excessive vomiting in pregnancy	0.000	0.994	0.006
H04.5 Stenosis and insufficiency of lachrymal passages	0.006	0.994	0.000
D73 Diseases of spleen	0.000	0.995	0.005
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.995	0.005
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.995	0.005
O29 Complications of anaesthesia during pregnancy	0.000	0.995	0.005
O22 Venous complications in pregnancy	0.000	0.995	0.005
O25 Malnutrition in pregnancy	0.000	0.995	0.005
O23 Infections of genito-urinary tract in pregnancy	0.000	0.995	0.005
Y43 Primarily systemic agents	0.000	0.995	0.005
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.995	0.005
I62.1 Nontraumatic extradural haemorrhage	0.000	0.995	0.005
I12 Hypertensive renal disease	0.000	0.995	0.005
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.995	0.005
I97.1 Other functional disturbances following cardiac surgery	0.001	0.995	0.004
D72 Other disorders of white blood cells	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.995	0.005
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.995	0.005
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
I35.1 Aortic (valve) insufficiency	0.000	0.995	0.005
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.995	0.005
D75.1 Secondary polycythaemia	0.000	0.995	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.001	0.995	0.004
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.995	0.005
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.995	0.005
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.995	0.005
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.995	0.005
D74.9 Methaemoglobinaemia, unspecified	0.000	0.995	0.005
D74.8 Other methaemoglobinaemias	0.000	0.995	0.005
D74.0 Congenital methaemoglobinaemia	0.000	0.995	0.005
O21.0 Mild hyperemesis gravidarum	0.000	0.995	0.005
I27.1 Kyphoscoliotic heart disease	0.000	0.995	0.005
I27.0 Primary pulmonary hypertension	0.000	0.995	0.005
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.995	0.005
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.995	0.005
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.995	0.005
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.995	0.005
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.995	0.005
D76.3 Other histiocytosis syndromes	0.000	0.995	0.004
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.995	0.004
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.995	0.004
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.995	0.004
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.995	0.004
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.995	0.004
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.995	0.004
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.995	0.004
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.995	0.004
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.995	0.004
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.004
I68.0 Cerebral amyloid angiopathy	0.000	0.995	0.004
L72 Follicular cysts of skin and subcutaneous tissue	0.000	0.995	0.005
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.001	0.995	0.004
G95.2 Cord compression, unspecified	0.005	0.995	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.995	0.004
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.995	0.004
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.995	0.004
M54.22 Cervicalgia (Cervical region)	0.000	0.995	0.005
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.995	0.004
I15.9 Seconday hypertension, unspecified	0.000	0.995	0.004
I15.8 Other secondary hypertension	0.000	0.995	0.004
I15.2 Hypertension secondary to endocrine disorders	0.000	0.995	0.004
I15.0 Renovascular hypertension	0.000	0.995	0.004
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
D75.0 Familial erythrocytosis	0.000	0.996	0.004
O21.9 Vomiting of pregnancy, unspecified	0.000	0.996	0.004
O21.8 Other vomiting complicating pregnancy	0.000	0.996	0.004
O21.2 Late vomiting of pregnancy	0.000	0.996	0.004
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.996	0.004
L72.0 Epidermal cyst	0.000	0.996	0.004
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.996	0.004
D75.2 Essential thrombocytosis	0.000	0.996	0.004
D73.9 Disease of spleen, unspecified	0.000	0.996	0.004
D73.8 Other diseases of spleen	0.000	0.996	0.004
D73.4 Cyst of spleen	0.000	0.996	0.004
D73.3 Abscess of spleen	0.000	0.996	0.004
D73.2 Chronic congestive splenomegaly	0.000	0.996	0.004
D73.1 Hypersplenism	0.000	0.996	0.004
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.004	0.996	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.996	0.004
O20 Haemorrhage in early pregnancy	0.000	0.996	0.004
O22.9 Venous complication in pregnancy, unspecified	0.000	0.996	0.004
O22.8 Other venous complications in pregnancy	0.000	0.996	0.004
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.996	0.004
O22.4 Haemorrhoids in pregnancy	0.000	0.996	0.004
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.996	0.004
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.996	0.004
O22.1 Genital varices in pregnancy	0.000	0.996	0.004
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.996	0.004
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.996	0.004
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.6 Failed or difficult intubation during pregnancy	0.000	0.996	0.004
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.996	0.004
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.996	0.004
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.996	0.004
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.996	0.004
I61 Intracerebral haemorrhage	0.000	0.996	0.004
I15.1 Hypertension secondary to other renal disorders	0.000	0.996	0.004
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.996	0.004
I63 Cerebral infarction	0.000	0.996	0.004
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.996	0.004
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.996	0.004
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.996	0.004
O23.2 Infections of urethra in pregnancy	0.000	0.996	0.004
O23.1 Infections of bladder in pregnancy	0.000	0.996	0.004
O23.0 Infections of kidney in pregnancy	0.000	0.996	0.004
D73.5 Infarction of spleen	0.000	0.996	0.004
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.996	0.004
Y43.9 Primarily systemic agent, unspecified	0.000	0.996	0.004
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.996	0.004
Y43.6 Enzymes, not elsewhere classified	0.000	0.996	0.004
Y43.5 Acidifying and alkalising agents	0.000	0.996	0.004
Y43.2 Antineoplastic natural products	0.000	0.996	0.004
Y43.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.000	0.996	0.004
O23.5 Infections of the genital tract in pregnancy	0.000	0.996	0.004
Y43.1 Antineoplastic antimetabolites	0.000	0.996	0.004
M84 Disorders of continuity of bone	0.004	0.996	0.000
I63.8 Other cerebral infarction	0.000	0.996	0.004
I60.8 Other subarachnoid haemorrhage	0.000	0.996	0.004
D72.9 Disorder of white blood cells, unspecified	0.000	0.996	0.004
D72.0 Genetic anomalies of leukocytes	0.000	0.996	0.004
I27.8 Other specified pulmonary heart diseases	0.000	0.996	0.003
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.996	0.003
M84.0 Malunion of fracture	0.004	0.996	0.000
D72.1 Eosinophilia	0.000	0.996	0.004
Y43.4 Immunosuppressive agents	0.000	0.996	0.004
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.996	0.003
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.996	0.003
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.996	0.003
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.996	0.003
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.996	0.003
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.996	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.996	0.003
G95 Other diseases of spinal cord	0.004	0.996	0.000
L72.2 Steatocystoma multiplex	0.000	0.996	0.003
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.996	0.003
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.001	0.996	0.003
I65.8 Occlusion and stenosis of other precerebral artery	0.001	0.996	0.003
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.001	0.996	0.003
I65.1 Occlusion and stenosis of basilar artery	0.001	0.996	0.003
I65.0 Occlusion and stenosis of vertebral artery	0.001	0.996	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.996	0.000
D73.0 Hyposplenism	0.000	0.996	0.003
G95.8 Other specified diseases of spinal cord	0.003	0.996	0.000
I35.0 Aortic (valve) stenosis	0.000	0.996	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
I95 Hypotension	0.000	0.997	0.003
N35 Urethral stricture	0.000	0.997	0.003
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.997	0.003
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.997	0.003
I61.8 Other intracerebral haemorrhage	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.997	0.003
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.997	0.003
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.997	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.997	0.003
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.997	0.003
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.997	0.003
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.997	0.003
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.997	0.003
G95.1 Vascular myelopathies	0.003	0.997	0.000
M50.1 Cervical disk disorder with radiculopathy	0.000	0.997	0.003
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.997	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
M84.3 Stress fracture, not elsewhere classified	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.997	0.003
H04 Disorders of lachrymal system	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
M84.09 Malunion of fracture (Site unspecified)	0.003	0.997	0.000
M84.08 Malunion of fracture (Other)	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
M84.01 Malunion of fracture (Shoulder region)	0.003	0.997	0.000
M84.00 Malunion of fracture (Multiple sites)	0.003	0.997	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.997	0.003
I95.2 Hypotension due to drugs	0.000	0.997	0.003
W13.9 Unspecified place	0.003	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.003	0.997	0.000
M17.1 Other primary gonarthrosis	0.000	0.997	0.003
H04.8 Other disorders of lachrymal system	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations