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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61248406
log Bayes Factor = 13.462
Chromosome 1   position 60,579,337  (GRCh37) Explore rs61248406 on Ensembl!
Variant rs61248406 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.997 0.003 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.992 0.008 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.990 0.010 0.000
M45-M49 Spondylopathies
0.988 0.012 0.000
C34 Malignant neoplasm of bronchus and lung
0.982 0.018 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.978 0.022 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
Z87 Personal history of other diseases and conditions
0.974 0.026 0.000
M47 Spondylosis
0.967 0.033 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
D50-D53 Nutritional anaemias
0.961 0.039 0.000
Chapter VII Diseases of the eye and adnexa
0.959 0.041 0.000
D50 Iron deficiency anaemia
0.956 0.044 0.000
Chapter XX External causes of morbidity and mortality
0.949 0.051 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.948 0.052 0.000
C77.1 Intrathoracic lymph nodes
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.947 0.053 0.000
G51 Facial nerve disorders
0.947 0.053 0.000
C79 Secondary malignant neoplasm of other sites
0.946 0.054 0.000
H25-H28 Disorders of lens
0.939 0.061 0.000
M25 Other joint disorders, not elsewhere classified
0.938 0.062 0.000
M80-M85 Disorders of bone density and structure
0.935 0.065 0.000
S00 Superficial injury of head
0.934 0.066 0.000
H26 Other cataract
0.933 0.067 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.929 0.071 0.000
D50.9 Iron deficiency anaemia, unspecified
0.929 0.071 0.000
M47.8 Other spondylosis
0.927 0.073 0.000
C34.3 Lower lobe, bronchus or lung
0.926 0.074 0.000
Z87.1 Personal history of diseases of the digestive system
0.925 0.075 0.000
C34.9 Bronchus or lung, unspecified
0.921 0.079 0.000
G56 Mononeuropathies of upper limb
0.920 0.080 0.000
H26.9 Cataract, unspecified
0.918 0.082 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.917 0.083 0.000
D00-D09 In situ neoplasms
0.914 0.086 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.912 0.088 0.000
M25.7 Osteophyte
0.906 0.094 0.000
M20 Acquired deformities of fingers and toes
0.903 0.097 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.903 0.097 0.000
G51.0 Bell's palsy
0.901 0.099 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.898 0.102 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.897 0.103 0.000
S00.8 Superficial injury of other parts of head
0.888 0.112 0.000
C77.0 Lymph nodes of head, face and neck
0.887 0.113 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.886 0.114 0.000
C77.5 Intrapelvic lymph nodes
0.884 0.116 0.000
C77.2 Intra-abdominal lymph nodes
0.882 0.118 0.000
M23 Internal derangement of knee
0.881 0.119 0.000
S01 Open wound of head
0.878 0.122 0.000
M24 Other specific joint derangements
0.877 0.123 0.000
M21 Other acquired deformities of limbs
0.876 0.124 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.874 0.126 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.871 0.129 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.869 0.131 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.868 0.132 0.000
Chapter IX Diseases of the circulatory system
0.865 0.135 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.863 0.137 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.862 0.138 0.000
I20-I25 Ischaemic heart diseases
0.862 0.138 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.861 0.139 0.000
C34.1 Upper lobe, bronchus or lung
0.860 0.140 0.000
Z83 Family history of other specific disorders
0.860 0.140 0.000
M47.9 Spondylosis, unspecified
0.858 0.142 0.000
M20.4 Other hammer toe(s) (acquired)
0.857 0.143 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.856 0.144 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.856 0.144 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.854 0.146 0.000
M47.86 Other spondylosis (Lumbar region)
0.854 0.146 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.853 0.147 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.853 0.147 0.000
D05 Carcinoma in situ of breast
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.850 0.150 0.000
M50-M54 Other dorsopathies
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.847 0.153 0.000
D50.8 Other iron deficiency anaemias
0.846 0.154 0.000
Z96 Presence of other functional implants
0.846 0.154 0.000
C51-C58 Malignant neoplasms of female genital organs
0.843 0.157 0.000
S02 Fracture of skull and facial bones
0.842 0.158 0.000
H26.4 After-cataract
0.840 0.160 0.000
S09 Other and unspecified injuries of head
0.837 0.163 0.000
I20 Angina pectoris
0.835 0.165 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.834 0.166 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.833 0.167 0.000
S90-S99 Injuries to the ankle and foot
0.832 0.168 0.000
M25.76 Osteophyte (Lower leg)
0.831 0.169 0.000
I25 Chronic ischaemic heart disease
0.830 0.170 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.828 0.172 0.000
M46 Other inflammatory spondylopathies
0.828 0.172 0.000
G90-G99 Other disorders of the nervous system
0.828 0.172 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.821 0.179 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.820 0.180 0.000
M47.82 Other spondylosis (Cervical region)
0.819 0.181 0.000
Chapter XI Diseases of the digestive system
0.818 0.182 0.000
Y52 Agents primarily affecting the cardiovascular system
0.817 0.183 0.000
Z96.0 Presence of urogenital implants
0.817 0.183 0.000
S20-S29 Injuries to the thorax
0.814 0.186 0.000
G56.0 Carpal tunnel syndrome
0.812 0.188 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.808 0.192 0.000
I20.9 Angina pectoris, unspecified
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.802 0.198 0.000
M25.77 Osteophyte (Ankle and foot)
0.801 0.198 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.801 0.199 0.000
C44 Other malignant neoplasms of skin
0.801 0.199 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.798 0.202 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.797 0.203 0.000
G56.2 Lesion of ulnar nerve
0.797 0.203 0.000
Z95.4 Presence of other heart-valve replacement
0.795 0.205 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.794 0.206 0.000
Z93 Artificial opening status
0.793 0.207 0.000
M85 Other disorders of bone density and structure
0.793 0.207 0.000
Z88.5 Personal history of allergy to narcotic agent
0.793 0.207 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.790 0.210 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.790 0.210 0.000
Z80 Family history of malignant neoplasm
0.789 0.211 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.788 0.212 0.000
K31 Other diseases of stomach and duodenum
0.787 0.213 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.787 0.213 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.785 0.215 0.000
M54 Dorsalgia
0.784 0.216 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.783 0.217 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.783 0.217 0.000
I24 Other acute ischaemic heart diseases
0.782 0.218 0.000
G30-G32 Other degenerative diseases of the nervous system
0.781 0.219 0.000
C77.4 Inguinal and lower limb lymph nodes
0.780 0.220 0.000
T86 Failure and rejection of transplanted organs and tissues
0.779 0.221 0.000
M23.8 Other internal derangements of knee
0.778 0.222 0.000
M45 Ankylosing spondylitis
0.773 0.227 0.000
Z99.3 Dependence on wheelchair
0.772 0.228 0.000
C80 Malignant neoplasm without specification of site
0.770 0.229 0.000
H53-H54 Visual disturbances and blindness
0.770 0.230 0.000
M47.89 Other spondylosis (Site unspecified)
0.770 0.230 0.000
W00-W19 Falls
0.767 0.233 0.000
H04 Disorders of lachrymal system
0.766 0.234 0.000
C73 Malignant neoplasm of thyroid gland
0.765 0.235 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.765 0.235 0.000
D05.1 Intraductal carcinoma in situ
0.764 0.236 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.764 0.236 0.000
I20.0 Unstable angina
0.763 0.237 0.000
M70-M79 Other soft tissue disorders
0.761 0.239 0.000
M24.5 Contracture of joint
0.761 0.239 0.000
M81 Osteoporosis without pathological fracture
0.760 0.240 0.000
Z95.2 Presence of prosthetic heart valve
0.760 0.240 0.000
C77.9 Lymph node, unspecified
0.760 0.240 0.000
G51.9 Disorder of facial nerve, unspecified
0.760 0.240 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.759 0.241 0.000
I05-I09 Chronic rheumatic heart diseases
0.759 0.241 0.000
Z95.0 Presence of cardiac pacemaker
0.758 0.242 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.757 0.243 0.000
M25.8 Other specified joint disorders
0.755 0.245 0.000
Z87.8 Personal history of other specified conditions
0.755 0.245 0.000
S06 Intracranial injury
0.754 0.246 0.000
I25.2 Old myocardial infarction
0.754 0.246 0.000
M91-M94 Chondropathies
0.751 0.249 0.000
K70-K77 Diseases of liver
0.750 0.250 0.000
G62 Other polyneuropathies
0.750 0.250 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.749 0.251 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.748 0.252 0.000
Z94 Transplanted organ and tissue status
0.748 0.252 0.000
S00.5 Superficial injury of lip and oral cavity
0.748 0.252 0.000
M23.3 Other meniscus derangements
0.748 0.252 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.747 0.253 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.746 0.254 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.746 0.254 0.000
Y00-Y09 Assault
0.744 0.256 0.000
C44.1 Skin of eyelid, including canthus
0.744 0.256 0.000
K31.7 Polyp of stomach and duodenum
0.744 0.256 0.000
M80 Osteoporosis with pathological fracture
0.743 0.257 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.742 0.257 0.000
G37 Other demyelinating diseases of central nervous system
0.741 0.259 0.000
G61 Inflammatory polyneuropathy
0.741 0.259 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.741 0.259 0.000
M48 Other spondylopathies
0.740 0.260 0.000
M31 Other necrotising vasculopathies
0.738 0.261 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.737 0.263 0.000
G58 Other mononeuropathies
0.736 0.264 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.736 0.264 0.000
L81 Other disorders of pigmentation
0.735 0.265 0.000
Z88.6 Personal history of allergy to analgesic agent
0.735 0.265 0.000
Z87.0 Personal history of diseases of the respiratory system
0.732 0.268 0.000
K25 Gastric ulcer
0.732 0.268 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.730 0.270 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.727 0.272 0.000
M25.3 Other instability of joint
0.726 0.273 0.000
L50-L54 Urticaria and erythema
0.726 0.274 0.000
S09.9 Unspecified injury of head
0.726 0.274 0.000
S02.2 Fracture of nasal bones
0.725 0.275 0.000
M65-M68 Disorders of synovium and tendon
0.725 0.275 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.725 0.275 0.000
G93 Other disorders of brain
0.725 0.275 0.000
M84 Disorders of continuity of bone
0.725 0.275 0.000
C32 Malignant neoplasm of larynx
0.724 0.275 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.724 0.276 0.000
S01.8 Open wound of other parts of head
0.722 0.277 0.000
M21.2 Flexion deformity
0.722 0.278 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.722 0.278 0.000
T66-T78 Other and unspecified effects of external causes
0.721 0.279 0.000
Z89 Acquired absence of limb
0.721 0.279 0.000
C78.2 Secondary malignant neoplasm of pleura
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
Y43 Primarily systemic agents
0.720 0.280 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.720 0.280 0.000
H26.1 Traumatic cataract
0.719 0.281 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.719 0.281 0.000
H27 Other disorders of lens
0.719 0.281 0.000
H10-H13 Disorders of conjunctiva
0.719 0.281 0.000
H01 Other inflammation of eyelid
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
D51 Vitamin B12 deficiency anaemia
0.716 0.284 0.000
S00.3 Superficial injury of nose
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M34 Systemic sclerosis
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.713 0.287 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
Y40 Systemic antibiotics
0.712 0.288 0.000
Z92 Personal history of medical treatment
0.712 0.288 0.000
M47.2 Other spondylosis with radiculopathy
0.712 0.288 0.000
C77.8 Lymph nodes of multiple regions
0.711 0.288 0.000
S01.4 Open wound of cheek and temporomandibular area
0.711 0.289 0.000
G54 Nerve root and plexus disorders
0.711 0.289 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.711 0.289 0.000
G52 Disorders of other cranial nerves
0.711 0.289 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
K29 Gastritis and duodenitis
0.710 0.290 0.000
K76 Other diseases of liver
0.710 0.290 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.710 0.290 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.710 0.290 0.000
C31 Malignant neoplasm of accessory sinuses
0.710 0.290 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.710 0.290 0.000
C37 Malignant neoplasm of thymus
0.710 0.290 0.000
C33 Malignant neoplasm of trachea
0.710 0.290 0.000
L20-L30 Dermatitis and eczema
0.709 0.291 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.709 0.291 0.000
M49 Spondylopathies in diseases classified elsewhere
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.706 0.294 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.706 0.294 0.000
Chapter I Certain infectious and parasitic diseases
0.706 0.294 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.705 0.295 0.000
S12 Fracture of neck
0.705 0.295 0.000
C34.8 Overlapping lesion of bronchus and lung
0.704 0.296 0.000
C34.2 Middle lobe, bronchus or lung
0.704 0.296 0.000
C34.0 Main bronchus
0.704 0.296 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.703 0.297 0.000
S01.2 Open wound of nose
0.703 0.297 0.000
G50 Disorders of trigeminal nerve
0.703 0.297 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.298 0.000
H04.2 Epiphora
0.702 0.298 0.000
Z84 Family history of other conditions
0.701 0.298 0.000
Z81 Family history of mental and behavioural disorders
0.701 0.298 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.699 0.301 0.000
L89 Decubitus ulcer
0.699 0.301 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.698 0.302 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.698 0.302 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.698 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
M25.9 Joint disorder, unspecified
0.696 0.304 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.695 0.304 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.694 0.306 0.000
C77.3 Axillary and upper limb lymph nodes
0.694 0.306 0.000
M47.1 Other spondylosis with myelopathy
0.694 0.306 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.694 0.306 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
I24.8 Other forms of acute ischaemic heart disease
0.692 0.308 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.691 0.309 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
M21.0 Valgus deformity, not elsewhere classified
0.691 0.309 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.690 0.310 0.000
I25.5 Ischaemic cardiomyopathy
0.689 0.310 0.000
S00.0 Superficial injury of scalp
0.689 0.311 0.000
M24.2 Disorder of ligament
0.689 0.311 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.689 0.311 0.000
D53 Other nutritional anaemias
0.689 0.311 0.000
D52 Folate deficiency anaemia
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.688 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.688 0.311 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.688 0.312 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.688 0.312 0.000
G60 Hereditary and idiopathic neuropathy
0.687 0.313 0.000
Z83.3 Family history of diabetes mellitus
0.687 0.313 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
T90 Sequelae of injuries of head
0.686 0.314 0.000
D50.1 Sideropenic dysphagia
0.686 0.314 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.685 0.315 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.684 0.316 0.000
L81.4 Other melanin hyperpigmentation
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.683 0.317 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.683 0.317 0.000
C71 Malignant neoplasm of brain
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.683 0.317 0.000
K35-K38 Diseases of appendix
0.683 0.317 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
S72 Fracture of femur
0.682 0.318 0.000
I05 Rheumatic mitral valve diseases
0.681 0.319 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.681 0.319 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.681 0.319 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
T87 Complications peculiar to reattachment and amputation
0.679 0.321 0.000
G51.8 Other disorders of facial nerve
0.679 0.321 0.000
G51.4 Facial myokymia
0.679 0.321 0.000
G51.3 Clonic hemifacial spasm
0.679 0.321 0.000
G51.2 Melkersson's syndrome
0.679 0.321 0.000
G51.1 Geniculate ganglionitis
0.679 0.321 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.679 0.321 0.000
C79.6 Secondary malignant neoplasm of ovary
0.678 0.322 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.678 0.322 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.678 0.322 0.000
M54.2 Cervicalgia
0.678 0.322 0.000
D60-D64 Aplastic and other anaemias
0.678 0.322 0.000
M20.2 Hallux rigidus
0.678 0.322 0.000
S02.7 Multiple fractures involving skull and facial bones
0.677 0.322 0.000
M24.56 Contracture of joint (Lower leg)
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
M22 Disorders of patella
0.676 0.324 0.000
S01.3 Open wound of ear
0.676 0.324 0.000
S01.0 Open wound of scalp
0.676 0.324 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.675 0.325 0.000
M77 Other enthesopathies
0.674 0.326 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.674 0.326 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.673 0.327 0.000
G95 Other diseases of spinal cord
0.673 0.327 0.000
M25.2 Flail joint
0.672 0.328 0.000
M25.1 Fistula of joint
0.672 0.328 0.000
M25.0 Haemarthrosis
0.672 0.328 0.000
T18 Foreign body in alimentary tract
0.672 0.328 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.672 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.672 0.328 0.000
C53 Malignant neoplasm of cervix uteri
0.672 0.328 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.671 0.329 0.000
H55-H59 Other disorders of eye and adnexa
0.671 0.329 0.000
M25.78 Osteophyte (Other)
0.671 0.329 0.000
M83 Adult osteomalacia
0.670 0.330 0.000
C79.2 Secondary malignant neoplasm of skin
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.670 0.330 0.000
M25.4 Effusion of joint
0.670 0.330 0.000
S00.7 Multiple superficial injuries of head
0.669 0.330 0.000
S00.4 Superficial injury of ear
0.669 0.330 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.669 0.330 0.000
H26.3 Drug-induced cataract
0.669 0.331 0.000
H26.2 Complicated cataract
0.669 0.331 0.000
H26.0 Infantile, juvenile and presenile cataract
0.669 0.331 0.000
Y52.1 Calcium-channel blockers
0.669 0.331 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.667 0.333 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.666 0.334 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.666 0.334 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.665 0.335 0.000
M47.84 Other spondylosis (Thoracic region)
0.665 0.335 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.665 0.335 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.665 0.335 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.664 0.336 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.664 0.336 0.000
C44.3 Skin of other and unspecified parts of face
0.664 0.336 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.663 0.336 0.000
C01 Malignant neoplasm of base of tongue
0.663 0.336 0.000
D03 Melanoma in situ
0.663 0.337 0.000
T42.4 Benzodiazepines
0.662 0.338 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.338 0.000
M21.1 Varus deformity, not elsewhere classified
0.662 0.338 0.000
M20.5 Other deformities of toe(s) (acquired)
0.662 0.338 0.000
Z96.1 Presence of intraocular lens
0.662 0.338 0.000
K29.7 Gastritis, unspecified
0.661 0.339 0.000
T17 Foreign body in respiratory tract
0.661 0.339 0.000
M21.6 Other acquired deformities of ankle and foot
0.661 0.339 0.000
M85.8 Other specified disorders of bone density and structure
0.660 0.340 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.660 0.340 0.000
G56.8 Other mononeuropathies of upper limb
0.660 0.340 0.000
G56.4 Causalgia
0.660 0.340 0.000
G56.3 Lesion of radial nerve
0.660 0.340 0.000
G56.1 Other lesions of median nerve
0.660 0.340 0.000
M23.5 Chronic instability of knee
0.660 0.340 0.000
G62.9 Polyneuropathy, unspecified
0.660 0.340 0.000
K65-K67 Diseases of peritoneum
0.659 0.341 0.000
K31.8 Other specified diseases of stomach and duodenum
0.659 0.341 0.000
C44.0 Skin of lip
0.659 0.341 0.000
T86.1 Kidney transplant failure and rejection
0.659 0.341 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.657 0.343 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.657 0.343 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.655 0.345 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.655 0.345 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.655 0.345 0.000
C56 Malignant neoplasm of ovary
0.655 0.345 0.000
Z95.3 Presence of xenogenic heart valve
0.654 0.346 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Y58 Bacterial vaccines
0.654 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.654 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.654 0.346 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.654 0.346 0.000
M86-M90 Other osteopathies
0.653 0.346 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.653 0.347 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.653 0.347 0.000
M24.0 Loose body in joint
0.653 0.347 0.000
Z93.6 Other artificial openings of urinary tract status
0.653 0.347 0.000
D09 Carcinoma in situ of other and unspecified sites
0.653 0.347 0.000
Z99.2 Dependence on renal dialysis
0.652 0.347 0.000
M23.4 Loose body in knee
0.652 0.348 0.000
M54.9 Dorsalgia, unspecified
0.652 0.348 0.000
S50-S59 Injuries to the elbow and forearm
0.651 0.349 0.000
T93 Sequelae of injuries of lower limb
0.651 0.349 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.650 0.349 0.000
M25.79 Osteophyte (Site unspecified)
0.649 0.351 0.000
M25.74 Osteophyte (Hand)
0.649 0.351 0.000
M25.73 Osteophyte (Forearm)
0.649 0.351 0.000
M25.72 Osteophyte (Upper arm)
0.649 0.351 0.000
M25.70 Osteophyte (Multiple sites)
0.649 0.351 0.000
M20.3 Other deformity of hallux (acquired)
0.649 0.351 0.000
K90-K93 Other diseases of the digestive system
0.649 0.351 0.000
S92 Fracture of foot, except ankle
0.648 0.351 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.648 0.352 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.647 0.353 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.647 0.353 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.647 0.353 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.647 0.353 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.646 0.354 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.646 0.354 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.645 0.355 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.645 0.355 0.000
C07 Malignant neoplasm of parotid gland
0.645 0.355 0.000
T91 Sequelae of injuries of neck and trunk
0.644 0.356 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.644 0.356 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.644 0.356 0.000
C54 Malignant neoplasm of corpus uteri
0.644 0.356 0.000
G64 Other disorders of peripheral nervous system
0.643 0.357 0.000
S00.1 Contusion of eyelid and periocular area
0.642 0.357 0.000
S19 Other and unspecified injuries of neck
0.642 0.358 0.000
S02.20 Fracture of nasal bones (closed)
0.642 0.358 0.000
C78.0 Secondary malignant neoplasm of lung
0.642 0.358 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.641 0.359 0.000
L84 Corns and callosities
0.641 0.359 0.000
G35 Multiple sclerosis
0.641 0.359 0.000
M81.9 Osteoporosis, unspecified
0.640 0.360 0.000
M53 Other dorsopathies, not elsewhere classified
0.640 0.360 0.000
Y44 Agents primarily affecting blood constituents
0.640 0.360 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.639 0.361 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.638 0.362 0.000
Z83.7 Family history of diseases of the digestive system
0.638 0.362 0.000
D04 Carcinoma in situ of skin
0.636 0.364 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.635 0.364 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.635 0.364 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.635 0.364 0.000
T83.2 Mechanical complication of graft of urinary organ
0.635 0.364 0.000
M23.9 Internal derangement of knee, unspecified
0.632 0.368 0.000
M23.1 Discoid meniscus (congenital)
0.632 0.368 0.000
M23.0 Cystic meniscus
0.632 0.368 0.000
Z97 Presence of other devices
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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