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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61280460
log Bayes Factor = 1.0785
Chromosome 14   position 94,796,184  (GRCh37) Explore rs61280460 on Ensembl!
Variant rs61280460 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.751 0.249 0.000
E88 Other metabolic disorders
0.474 0.526 0.000
E88.2 Lipomatosis, not elsewhere classified
0.398 0.601 0.000
E88.3 Tumour lysis syndrome
0.367 0.632 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.352 0.648 0.000
I25.2 Old myocardial infarction
0.000 0.651 0.349
I25 Chronic ischaemic heart disease
0.000 0.652 0.348
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.655 0.345
E88.9 Metabolic disorder, unspecified
0.340 0.660 0.000
E88.8 Other specified metabolic disorders
0.334 0.666 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.681 0.319
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.693 0.307
F10.3 Withdrawal state
0.000 0.695 0.305
F10.0 Acute intoxication
0.000 0.698 0.302
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.709 0.291
F10.2 Dependence syndrome
0.000 0.715 0.285
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.719 0.281
F10.1 Harmful use
0.000 0.720 0.280
I25.3 Aneurysm of heart
0.000 0.730 0.269
F10.5 Psychotic disorder
0.000 0.757 0.243
I25.4 Coronary artery aneurysm
0.000 0.762 0.238
F10.8 Other mental and behavioural disorders
0.000 0.780 0.220
F10.7 Residual and late-onset psychotic disorder
0.000 0.780 0.220
F10.4 Withdrawal state with delirium
0.000 0.783 0.217
I25.6 Silent myocardial ischaemia
0.000 0.784 0.215
F10.9 Unspecified mental and behavioural disorder
0.000 0.798 0.202
Z50 Care involving use of rehabilitation procedures
0.000 0.801 0.199
I25.1 Atherosclerotic heart disease
0.000 0.803 0.197
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.804 0.196
Z50.5 Speech therapy
0.000 0.810 0.190
F10.6 Amnesic syndrome
0.000 0.817 0.183
Z50.1 Other physical therapy
0.000 0.820 0.180
Z50.4 Psychotherapy, not elsewhere classified
0.000 0.824 0.176
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.824 0.176
Z50.2 Alcohol rehabilitation
0.000 0.837 0.163
Z50.0 Cardiac rehabilitation
0.000 0.845 0.155
Z50.6 Orthoptic training
0.000 0.857 0.143
Z50.3 Drug rehabilitation
0.000 0.857 0.143
Z50.8 Care involving use of rehabilitation procedures
0.000 0.881 0.119
T39.1 4-Aminophenol derivatives
0.000 0.894 0.106
I20-I25 Ischaemic heart diseases
0.000 0.897 0.103
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.903 0.097
I21 Acute myocardial infarction
0.000 0.903 0.097
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.908 0.092
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.913 0.087
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.913 0.087
I23 Certain current complications following acute myocardial infarction
0.000 0.923 0.077
K74.6 Other and unspecified cirrhosis of liver
0.072 0.928 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.930 0.069
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.931 0.069
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.934 0.066
T39.4 Antirheumatics, not elsewhere classified
0.000 0.937 0.062
T39.2 Pyrazolone derivatives
0.000 0.937 0.062
K74 Fibrosis and cirrhosis of liver
0.062 0.938 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.938 0.062
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.940 0.060
K74.3 Primary biliary cirrhosis
0.059 0.941 0.000
I22 Subsequent myocardial infarction
0.000 0.942 0.057
I23.8 Other current complications following acute myocardial infarction
0.000 0.942 0.058
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.944 0.055
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.945 0.055
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.945 0.055
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.945 0.055
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.945 0.055
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.945 0.055
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.945 0.055
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.945 0.055
I24 Other acute ischaemic heart diseases
0.000 0.946 0.054
K74.0 Hepatic fibrosis
0.053 0.947 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.954 0.046
I24.8 Other forms of acute ischaemic heart disease
0.000 0.954 0.046
K74.4 Secondary biliary cirrhosis
0.045 0.955 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.045 0.955 0.000
K74.1 Hepatic sclerosis
0.045 0.955 0.000
K74.5 Biliary cirrhosis, unspecified
0.043 0.956 0.000
I24.1 Dressler's syndrome
0.000 0.957 0.043
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.963 0.037
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.967 0.033
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.967 0.033
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.967 0.033
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.967 0.033
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.967 0.033
F19.1 Harmful use
0.000 0.970 0.030
I21.4 Acute subendocardial myocardial infarction
0.000 0.970 0.030
F19.9 Unspecified mental and behavioural disorder
0.000 0.973 0.026
F19.8 Other mental and behavioural disorders
0.000 0.973 0.026
F19.7 Residual and late-onset psychotic disorder
0.000 0.973 0.026
F19.6 Amnesic syndrome
0.000 0.973 0.026
F19.5 Psychotic disorder
0.000 0.973 0.026
F19.4 Withdrawal state with delirium
0.000 0.973 0.026
F19.3 Withdrawal state
0.000 0.973 0.026
F19.2 Dependence syndrome
0.000 0.973 0.026
F19.0 Acute intoxication
0.000 0.973 0.026
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.973 0.026
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.974 0.026
F12.1 Harmful use
0.000 0.974 0.026
F13.2 Dependence syndrome
0.000 0.975 0.024
F11 Mental and behavioural disorders due to use of opioids
0.000 0.975 0.024
I22.8 Subsequent myocardial infarction of other sites
0.001 0.976 0.023
F13.9 Unspecified mental and behavioural disorder
0.000 0.976 0.024
F13.8 Other mental and behavioural disorders
0.000 0.976 0.024
F13.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F13.6 Amnesic syndrome
0.000 0.976 0.024
F13.5 Psychotic disorder
0.000 0.976 0.024
F13.4 Withdrawal state with delirium
0.000 0.976 0.024
F13.3 Withdrawal state
0.000 0.976 0.024
F13.1 Harmful use
0.000 0.976 0.024
F13.0 Acute intoxication
0.000 0.976 0.024
F14.9 Unspecified mental and behavioural disorder
0.000 0.976 0.024
F14.8 Other mental and behavioural disorders
0.000 0.976 0.024
F14.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F14.6 Amnesic syndrome
0.000 0.976 0.024
F14.5 Psychotic disorder
0.000 0.976 0.024
F14.4 Withdrawal state with delirium
0.000 0.976 0.024
F14.3 Withdrawal state
0.000 0.976 0.024
F14.2 Dependence syndrome
0.000 0.976 0.024
F14.1 Harmful use
0.000 0.976 0.024
F14.0 Acute intoxication
0.000 0.976 0.024
F16.9 Unspecified mental and behavioural disorder
0.000 0.976 0.024
F16.8 Other mental and behavioural disorders
0.000 0.976 0.024
F16.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F16.6 Amnesic syndrome
0.000 0.976 0.024
F16.5 Psychotic disorder
0.000 0.976 0.024
F16.4 Withdrawal state with delirium
0.000 0.976 0.024
F16.3 Withdrawal state
0.000 0.976 0.024
F16.2 Dependence syndrome
0.000 0.976 0.024
F16.1 Harmful use
0.000 0.976 0.024
F16.0 Acute intoxication
0.000 0.976 0.024
F18.9 Unspecified mental and behavioural disorder
0.000 0.976 0.024
F18.8 Other mental and behavioural disorders
0.000 0.976 0.024
F18.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F18.6 Amnesic syndrome
0.000 0.976 0.024
F18.5 Psychotic disorder
0.000 0.976 0.024
F18.4 Withdrawal state with delirium
0.000 0.976 0.024
F18.3 Withdrawal state
0.000 0.976 0.024
F18.2 Dependence syndrome
0.000 0.976 0.024
F18.1 Harmful use
0.000 0.976 0.024
F18.0 Acute intoxication
0.000 0.976 0.024
F12.9 Unspecified mental and behavioural disorder
0.000 0.976 0.024
F12.8 Other mental and behavioural disorders
0.000 0.976 0.024
F12.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F12.6 Amnesic syndrome
0.000 0.976 0.024
F12.5 Psychotic disorder
0.000 0.976 0.024
F12.4 Withdrawal state with delirium
0.000 0.976 0.024
F12.3 Withdrawal state
0.000 0.976 0.024
F12.0 Acute intoxication
0.000 0.976 0.024
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.978 0.021
F12.2 Dependence syndrome
0.000 0.979 0.020
I22.1 Subsequent myocardial infarction of inferior wall
0.001 0.981 0.019
F15.9 Unspecified mental and behavioural disorder
0.000 0.981 0.019
F15.8 Other mental and behavioural disorders
0.000 0.981 0.019
F15.7 Residual and late-onset psychotic disorder
0.000 0.981 0.019
F15.6 Amnesic syndrome
0.000 0.981 0.019
F15.5 Psychotic disorder
0.000 0.981 0.019
F15.4 Withdrawal state with delirium
0.000 0.981 0.019
F15.3 Withdrawal state
0.000 0.981 0.019
F15.2 Dependence syndrome
0.000 0.981 0.019
F15.0 Acute intoxication
0.000 0.981 0.019
T39.0 Salicylates
0.001 0.982 0.017
F11.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F11.8 Other mental and behavioural disorders
0.000 0.982 0.018
F11.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F11.6 Amnesic syndrome
0.000 0.982 0.018
F11.5 Psychotic disorder
0.000 0.982 0.018
F11.4 Withdrawal state with delirium
0.000 0.982 0.018
F11.0 Acute intoxication
0.000 0.982 0.018
F11.1 Harmful use
0.000 0.982 0.017
F11.3 Withdrawal state
0.000 0.984 0.016
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.985 0.015
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.986 0.014
T40.2 Other opioids
0.000 0.986 0.014
K70-K77 Diseases of liver
0.014 0.986 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.986 0.014
I20 Angina pectoris
0.000 0.986 0.014
Q05.9 Spina bifida, unspecified
0.013 0.987 0.000
Z34.8 Supervision of other normal pregnancy
0.013 0.987 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.013 0.987 0.000
F15.1 Harmful use
0.001 0.987 0.012
Q05 Spina bifida
0.013 0.987 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.013 0.987 0.000
Q00-Q07 Congenital malformations of the nervous system
0.012 0.988 0.000
F11.2 Dependence syndrome
0.001 0.988 0.012
Q60-Q64 Congenital malformations of the urinary system
0.012 0.988 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.012 0.988 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.988 0.012
K71 Toxic liver disease
0.012 0.988 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.012 0.988 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.988 0.012
T40.6 Other and unspecified narcotics
0.000 0.988 0.011
F17.9 Unspecified mental and behavioural disorder
0.000 0.989 0.011
F17.8 Other mental and behavioural disorders
0.000 0.989 0.011
F17.7 Residual and late-onset psychotic disorder
0.000 0.989 0.011
F17.6 Amnesic syndrome
0.000 0.989 0.011
F17.5 Psychotic disorder
0.000 0.989 0.011
F17.4 Withdrawal state with delirium
0.000 0.989 0.011
F17.3 Withdrawal state
0.000 0.989 0.011
F17.0 Acute intoxication
0.000 0.989 0.011
Q60 Renal agenesis and other reduction defects of kidney
0.011 0.989 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.989 0.011
Q66 Congenital deformities of feet
0.011 0.989 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.011 0.989 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.011 0.989 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.011 0.989 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.989 0.010
Q80-Q89 Other congenital malformations
0.011 0.989 0.000
K72 Hepatic failure, not elsewhere classified
0.011 0.989 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.989 0.010
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.989 0.010
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.989 0.010
K76 Other diseases of liver
0.011 0.989 0.000
K77 Liver disorders in diseases classified elsewhere
0.010 0.990 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.010 0.990 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.990 0.010
T40.8 Lysergide [LSD]
0.000 0.990 0.010
T40.7 Cannabis (derivatives)
0.000 0.990 0.010
T40.5 Cocaine
0.000 0.990 0.010
T40.3 Methadone
0.000 0.990 0.010
T40.0 Opium
0.000 0.990 0.010
Q76 Congenital malformations of spine and bony thorax
0.010 0.990 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.010 0.990 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.010 0.990 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.010 0.990 0.000
N39.8 Other specified disorders of urinary system
0.000 0.990 0.010
T40.4 Other synthetic narcotics
0.000 0.990 0.010
T36 Poisoning by systemic antibiotics
0.000 0.990 0.010
Q60.0 Renal agenesis, unilateral
0.010 0.990 0.000
T42.1 Iminostilbenes
0.000 0.990 0.010
Q63 Other congenital malformations of kidney
0.010 0.990 0.000
Q74 Other congenital malformations of limb(s)
0.010 0.990 0.000
Q62.5 Duplication of ureter
0.010 0.990 0.000
Q82 Other congenital malformations of skin
0.010 0.990 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.010 0.990 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.990 0.010
M62.86 Other specified disorders of muscle (Lower leg)
0.010 0.990 0.000
Q05.4 Unspecified spina bifida with hydrocephalus
0.009 0.990 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.990 0.010
K72.0 Acute and subacute hepatic failure
0.010 0.990 0.000
Q35-Q37 Cleft lip and cleft palate
0.010 0.990 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.010 0.990 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.009 0.991 0.000
Q66.6 Other congenital valgus deformities of feet
0.009 0.991 0.000
Q05.8 Sacral spina bifida without hydrocephalus
0.009 0.991 0.000
Q05.7 Lumbar spina bifida without hydrocephalus
0.009 0.991 0.000
Q05.6 Thoracic spina bifida without hydrocephalus
0.009 0.991 0.000
Q05.5 Cervical spina bifida without hydrocephalus
0.009 0.991 0.000
Q05.3 Sacral spina bifida with hydrocephalus
0.009 0.991 0.000
Q05.2 Lumbar spina bifida with hydrocephalus
0.009 0.991 0.000
Q05.1 Thoracic spina bifida with hydrocephalus
0.009 0.991 0.000
Q05.0 Cervical spina bifida with hydrocephalus
0.009 0.991 0.000
Q66.3 Other congenital varus deformities of feet
0.009 0.991 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.009 0.991 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.991 0.009
Q60.2 Renal agenesis, unspecified
0.009 0.991 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.991 0.009
K75 Other inflammatory liver diseases
0.009 0.991 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.991 0.009
C90 Multiple myeloma and malignant plasma cell neoplasms
0.009 0.991 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.991 0.009
K71.0 Toxic liver disease with cholestasis
0.009 0.991 0.000
C90.0 Multiple myeloma
0.009 0.991 0.000
C91.1 Chronic lymphocytic leukaemia
0.009 0.991 0.000
M62.8 Other specified disorders of muscle
0.009 0.991 0.000
Q27 Other congenital malformations of peripheral vascular system
0.009 0.991 0.000
K75.8 Other specified inflammatory liver diseases
0.009 0.991 0.000
Q44.6 Cystic disease of liver
0.009 0.991 0.000
Q06 Other congenital malformations of spinal cord
0.009 0.991 0.000
Q04 Other congenital malformations of brain
0.009 0.991 0.000
Q03 Congenital hydrocephalus
0.009 0.991 0.000
Q01 Encephalocele
0.009 0.991 0.000
Q00 Anencephaly and similar malformations
0.009 0.991 0.000
Q02 Microcephaly
0.009 0.991 0.000
Q40 Other congenital malformations of upper alimentary tract
0.009 0.991 0.000
Q39 Congenital malformations of oesophagus
0.009 0.991 0.000
K73 Chronic hepatitis, not elsewhere classified
0.009 0.991 0.000
Q76.0 Spina bifida occulta
0.009 0.991 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.009 0.991 0.000
Q75 Other congenital malformations of skull and face bones
0.009 0.991 0.000
Q73 Reduction defects of unspecified limb
0.009 0.991 0.000
Q72 Reduction defects of lower limb
0.009 0.991 0.000
Q71 Reduction defects of upper limb
0.009 0.991 0.000
Q70 Syndactyly
0.009 0.991 0.000
Q69 Polydactyly
0.009 0.991 0.000
Q68 Other congenital musculoskeletal deformities
0.009 0.991 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.991 0.009
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.991 0.009
T42.3 Barbiturates
0.000 0.991 0.009
T42.2 Succinimides and oxazolidinediones
0.000 0.991 0.009
Q83 Congenital malformations of breast
0.009 0.991 0.000
Q66.9 Congenital deformity of feet, unspecified
0.009 0.991 0.000
T40.1 Heroin
0.000 0.991 0.009
Q43 Other congenital malformations of intestine
0.009 0.991 0.000
Q82.5 Congenital nonneoplastic naevus
0.009 0.991 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.009 0.991 0.000
K71.9 Toxic liver disease, unspecified
0.009 0.991 0.000
K71.8 Toxic liver disease with other disorders of liver
0.009 0.991 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.009 0.991 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.009 0.991 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.009 0.991 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.009 0.991 0.000
K71.2 Toxic liver disease with acute hepatitis
0.009 0.991 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.009 0.991 0.000
C85.1 B-cell lymphoma, unspecified
0.009 0.991 0.000
Q45 Other congenital malformations of digestive system
0.009 0.991 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.009 0.991 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.009 0.991 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.009 0.991 0.000
Q74.1 Congenital malformation of knee
0.008 0.991 0.000
Q66.8 Other congenital deformities of feet
0.009 0.991 0.000
C91 Lymphoid leukaemia
0.009 0.991 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.991 0.008
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.991 0.008
K76.8 Other specified diseases of liver
0.008 0.992 0.000
Q28 Other congenital malformations of circulatory system
0.008 0.992 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.008 0.992 0.000
Q67.6 Pectus excavatum
0.008 0.992 0.000
Q82.0 Hereditary lymphoedema
0.008 0.992 0.000
Q24 Other congenital malformations of heart
0.008 0.992 0.000
T42.0 Hydantoin derivatives
0.000 0.992 0.008
Q60.6 Potter's syndrome
0.008 0.992 0.000
Q60.5 Renal hypoplasia, unspecified
0.008 0.992 0.000
Q60.4 Renal hypoplasia, bilateral
0.008 0.992 0.000
Q60.3 Renal hypoplasia, unilateral
0.008 0.992 0.000
Q60.1 Renal agenesis, bilateral
0.008 0.992 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.008 0.992 0.000
Q96 Turner's syndrome
0.008 0.992 0.000
Q25 Congenital malformations of great arteries
0.008 0.992 0.000
Q64 Other congenital malformations of urinary system
0.008 0.992 0.000
I20.8 Other forms of angina pectoris
0.000 0.992 0.008
Q07 Other congenital malformations of nervous system
0.008 0.992 0.000
Q65 Congenital deformities of hip
0.008 0.992 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.008 0.992 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.008 0.992 0.000
Q67.5 Congenital deformity of spine
0.008 0.992 0.000
Q66.5 Congenital pes planus
0.008 0.992 0.000
Q66.4 Talipes calcaneovalgus
0.008 0.992 0.000
Q66.1 Talipes calcaneovarus
0.008 0.992 0.000
Q66.0 Talipes equinovarus
0.008 0.992 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.992 0.008
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.992 0.008
T47.7 Emetics
0.000 0.992 0.008
T47.6 Antidiarrhoeal drugs
0.000 0.992 0.008
T47.5 Digestants
0.000 0.992 0.008
T47.4 Other laxatives
0.000 0.992 0.008
T47.3 Saline and osmotic laxatives
0.000 0.992 0.008
T47.2 Stimulant laxatives
0.000 0.992 0.008
T47.0 Histamine H(2)-receptor antagonists
0.000 0.992 0.008
Q78 Other osteochondrodysplasias
0.008 0.992 0.000
K76.6 Portal hypertension
0.008 0.992 0.000
Q76.1 Klippel-Feil syndrome
0.008 0.992 0.000
Q26 Congenital malformations of great veins
0.008 0.992 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.008 0.992 0.000
Q76.5 Cervical rib
0.008 0.992 0.000
Q38.7 Pharyngeal pouch
0.008 0.992 0.000
C90.2 Plasmacytoma, extramedullary
0.008 0.992 0.000
Q62.8 Other congenital malformations of ureter
0.008 0.992 0.000
Q62.7 Congenital vesico-uretero-renal reflux
0.008 0.992 0.000
Q62.6 Malposition of ureter
0.008 0.992 0.000
Q62.4 Agenesis of ureter
0.008 0.992 0.000
Q62.3 Other obstructive defects of renal pelvis and ureter
0.008 0.992 0.000
Q62.2 Congenital megaloureter
0.008 0.992 0.000
Q62.1 Atresia and stenosis of ureter
0.008 0.992 0.000
Q62.0 Congenital hydronephrosis
0.008 0.992 0.000
Q83.1 Accessory breast
0.008 0.992 0.000
Q61 Cystic kidney disease
0.008 0.992 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.008 0.992 0.000
Q84 Other congenital malformations of integument
0.008 0.992 0.000
Q81 Epidermolysis bullosa
0.008 0.992 0.000
Q80 Congenital ichthyosis
0.008 0.992 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.008 0.992 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.992 0.008
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.992 0.008
T37.5 Antiviral drugs
0.000 0.992 0.008
T37.4 Anthelminthics
0.000 0.992 0.008
T37.3 Other antiprotozoal drugs
0.000 0.992 0.008
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.992 0.008
T37.1 Antimycobacterial drugs
0.000 0.992 0.008
T37.0 Sulphonamides
0.000 0.992 0.008
T41.5 Therapeutic gases
0.000 0.992 0.008
T41.4 Anaesthetic, unspecified
0.000 0.992 0.008
T41.3 Local anaesthetics
0.000 0.992 0.008
T41.2 Other and unspecified general anaesthetics
0.000 0.992 0.008
T41.1 Intravenous anaesthetics
0.000 0.992 0.008
T41.0 Inhaled anaesthetics
0.000 0.992 0.008
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.992 0.008
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.992 0.008
T48.5 Anti-common-cold drugs
0.000 0.992 0.008
T48.4 Expectorants
0.000 0.992 0.008
T48.3 Antitussives
0.000 0.992 0.008
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.992 0.008
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.992 0.008
T48.0 Oxytocic drugs
0.000 0.992 0.008
K72.1 Chronic hepatic failure
0.008 0.992 0.000
K76.5 Hepatic veno-occlusive disease
0.008 0.992 0.000
K76.4 Peliosis hepatis
0.008 0.992 0.000
K76.3 Infarction of liver
0.008 0.992 0.000
K76.2 Central haemorrhagic necrosis of liver
0.008 0.992 0.000
K76.1 Chronic passive congestion of liver
0.008 0.992 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.008 0.992 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.008 0.992 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.008 0.992 0.000
C85.0 Lymphosarcoma
0.008 0.992 0.000
Q39.6 Diverticulum of oesophagus
0.008 0.992 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.008 0.992 0.000
Q23 Congenital malformations of aortic and mitral valves
0.008 0.992 0.000
Q66.2 Metatarsus varus
0.008 0.992 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.008 0.992 0.000
Q76.8 Other congenital malformations of bony thorax
0.008 0.992 0.000
Q76.7 Congenital malformation of sternum
0.008 0.992 0.000
Q76.6 Other congenital malformations of ribs
0.008 0.992 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.008 0.992 0.000
Q76.2 Congenital spondylolisthesis
0.008 0.992 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.008 0.992 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.007 0.992 0.000
Q82.2 Mastocytosis
0.007 0.992 0.000
Q44.7 Other congenital malformations of liver
0.007 0.992 0.000
Q44.5 Other congenital malformations of bile ducts
0.007 0.992 0.000
Q44.4 Choledochal cyst
0.007 0.992 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.007 0.992 0.000
Q44.2 Atresia of bile ducts
0.007 0.992 0.000
Q44.1 Other congenital malformations of gallbladder
0.007 0.992 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.007 0.992 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.992 0.008
Q67.8 Other congenital deformities of chest
0.007 0.992 0.000
Q67.7 Pectus carinatum
0.007 0.992 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.007 0.992 0.000
Q67.3 Plagiocephaly
0.007 0.992 0.000
Q67.2 Dolichocephaly
0.007 0.992 0.000
Q67.1 Compression facies
0.007 0.992 0.000
Q67.0 Facial asymmetry
0.007 0.992 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.007 0.992 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.007 0.992 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.007 0.992 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.007 0.992 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.007 0.992 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.007 0.992 0.000
Q90 Down's syndrome
0.007 0.992 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.007 0.992 0.000
T36.9 Systemic antibiotic, unspecified
0.000 0.992 0.007
T36.8 Other systemic antibiotics
0.000 0.992 0.007
T36.7 Antifungal antibiotics, systemically used
0.000 0.992 0.007
T36.6 Rifamycins
0.000 0.992 0.007
T36.5 Aminoglycosides
0.000 0.992 0.007
T36.4 Tetracyclines
0.000 0.992 0.007
T36.3 Macrolides
0.000 0.992 0.007
T36.2 Chloramphenicol group
0.000 0.992 0.007
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.992 0.007
Q63.2 Ectopic kidney
0.007 0.993 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.007 0.993 0.000
Q37 Cleft palate with cleft lip
0.007 0.993 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.007 0.993 0.000
Q63.8 Other specified congenital malformations of kidney
0.007 0.993 0.000
Q63.3 Hyperplastic and giant kidney
0.007 0.993 0.000
Q21 Congenital malformations of cardiac septa
0.007 0.993 0.000
Q63.0 Accessory kidney
0.007 0.993 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.007 0.993 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.007 0.993 0.000
Q74.3 Arthrogryposis multiplex congenita
0.007 0.993 0.000
F17.1 Harmful use
0.000 0.993 0.007
Q43.1 Hirschsprung's disease
0.007 0.993 0.000
Q82.9 Congenital malformation of skin, unspecified
0.007 0.993 0.000
Q82.4 Ectodermal dysplasia (anhidrotic)
0.007 0.993 0.000
Q82.3 Incontinentia pigmenti
0.007 0.993 0.000
Q82.1 Xeroderma pigmentosum
0.007 0.993 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.993 0.007
Q66.7 Pes cavus
0.007 0.993 0.000
T49.9 Topical agent, unspecified
0.000 0.993 0.007
T49.8 Other topical agents
0.000 0.993 0.007
T49.7 Dental drugs, topically applied
0.000 0.993 0.007
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.993 0.007
T49.5 Ophthalmological drugs and preparations
0.000 0.993 0.007
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.993 0.007
T49.3 Emollients, demulcents and protectants
0.000 0.993 0.007
T49.2 Local astringents and local detergents
0.000 0.993 0.007
T49.1 Antipruritics
0.000 0.993 0.007
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.007 0.993 0.000
Q40.2 Other specified congenital malformations of stomach
0.007 0.993 0.000
C86 Other specified types of T/NK-cell lymphoma
0.007 0.993 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.993 0.007
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.993 0.007
T46.7 Peripheral vasodilators
0.000 0.993 0.007
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.993 0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.993 0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.993 0.007
Q36 Cleft lip
0.007 0.993 0.000
Q35 Cleft palate
0.007 0.993 0.000
Q25.3 Stenosis of aorta
0.007 0.993 0.000
Q38.8 Other congenital malformations of pharynx
0.007 0.993 0.000
Q38.6 Other congenital malformations of mouth
0.007 0.993 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.007 0.993 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.007 0.993 0.000
Q38.3 Other congenital malformations of tongue
0.007 0.993 0.000
Q38.2 Macroglossia
0.007 0.993 0.000
Q38.1 Ankyloglossia
0.007 0.993 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.007 0.993 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.007 0.993 0.000
D80 Immunodeficiency with predominantly antibody defects
0.007 0.993 0.000
Q24.8 Other specified congenital malformations of heart
0.007 0.993 0.000
Q43.0 Meckel's diverticulum
0.007 0.993 0.000
Q89 Other congenital malformations, not elsewhere classified
0.007 0.993 0.000
D63.0 Anaemia in neoplastic disease
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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