TreeWAS – Variant ID: rs62020330

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.995	0.005
Chapter IX Diseases of the circulatory system	0.992	0.008
I77 Other disorders of arteries and arterioles	0.991	0.009
I77.1 Stricture of artery	0.987	0.013
H90-H95 Other disorders of ear	0.985	0.015
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.985	0.015
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.983	0.017
I74 Arterial embolism and thrombosis	0.982	0.018
Chapter XX External causes of morbidity and mortality	0.974	0.026
R20 Disturbances of skin sensation	0.973	0.027
R20.2 Paraesthesia of skin	0.971	0.029
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.969	0.031
B95-B98 Bacterial, viral and other infectious agents	0.961	0.039
H93 Other disorders of ear, not elsewhere classified	0.958	0.042
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.957	0.043
T85 Complications of other internal prosthetic devices, implants and grafts	0.954	0.046
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.949	0.051
R93 Abnormal findings on diagnostic imaging of other body structures	0.947	0.053
S60-S69 Injuries to the wrist and hand	0.946	0.054
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.945	0.055
H93.1 Tinnitus	0.939	0.061
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.938	0.062
H65-H75 Diseases of middle ear and mastoid	0.934	0.066
S70-S79 Injuries to the hip and thigh	0.931	0.069
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.930	0.070
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.924	0.076
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.922	0.078
Chapter IV Endocrine, nutritional and metabolic diseases	0.921	0.079
I05-I09 Chronic rheumatic heart diseases	0.919	0.081
I73 Other peripheral vascular diseases	0.917	0.083
B25-B34 Other viral diseases	0.909	0.091
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.906	0.094
A30-A49 Other bacterial diseases	0.896	0.104
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.891	0.109
I73.9 Peripheral vascular disease, unspecified	0.886	0.114
S64 Injury of nerves at wrist and hand level	0.885	0.115
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.885	0.115
S61 Open wound of wrist and hand	0.879	0.121
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.878	0.122
E50-E64 Other nutritional deficiencies	0.876	0.124
H60-H62 Diseases of external ear	0.875	0.125
R21 Rash and other nonspecific skin eruption	0.875	0.125
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.875	0.125
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.874	0.125
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.873	0.127
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.873	0.127
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.869	0.131
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.867	0.133
E20-E35 Disorders of other endocrine glands	0.858	0.142
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.856	0.144
B15-B19 Viral hepatitis	0.856	0.144
B07 Viral warts	0.854	0.146
S72 Fracture of femur	0.853	0.147
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.849	0.151
B34 Viral infection of unspecified site	0.846	0.154
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.845	0.155
S20-S29 Injuries to the thorax	0.843	0.157
A41 Other septicaemia	0.842	0.158
H92 Otalgia and effusion of ear	0.841	0.159
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.839	0.161
T66-T78 Other and unspecified effects of external causes	0.838	0.162
T15-T19 Effects of foreign body entering through natural orifice	0.838	0.162
I74.5 Embolism and thrombosis of iliac artery	0.833	0.167
A80-A89 Viral infections of the central nervous system	0.832	0.168
T87 Complications peculiar to reattachment and amputation	0.830	0.170
Y60-Y69 Misadventures to patients during surgical and medical care	0.828	0.172
I08 Multiple valve diseases	0.826	0.174
E53 Deficiency of other B group vitamins	0.825	0.175
S61.9 Open wound of wrist and hand, part unspecified	0.824	0.176
H65 Nonsuppurative otitis media	0.823	0.177
H80-H83 Diseases of inner ear	0.819	0.181
H61 Other disorders of external ear	0.817	0.183
Y83.4 Other reconstructive surgery	0.814	0.186
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.813	0.187
T20-T25 Burns and corrosions of external body surface, specified by site	0.809	0.191
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.808	0.192
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.807	0.193
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.803	0.197
S64.3 Injury of digital nerve of thumb	0.803	0.197
I72 Other aneurysm	0.797	0.203
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.796	0.204
X20-X29 Contact with venomous animals and plants	0.794	0.206
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.794	0.206
X50-X57 Overexertion, travel and privation	0.793	0.207
T83.3 Mechanical complication of intra-uterine contraceptive device	0.792	0.208
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.791	0.209
R27 Other lack of coordination	0.790	0.210
E53.8 Deficiency of other specified B group vitamins	0.789	0.211
B34.9 Viral infection, unspecified	0.788	0.212
I74.8 Embolism and thrombosis of other arteries	0.784	0.216
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.783	0.217
I77.9 Disorder of arteries and arterioles, unspecified	0.782	0.218
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.782	0.218
T14 Injury of unspecified body region	0.782	0.218
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.780	0.220
T36-T50 Poisoning by drugs, medicaments and biological substances	0.778	0.222
R90 Abnormal findings on diagnostic imaging of central nervous system	0.778	0.222
S50-S59 Injuries to the elbow and forearm	0.778	0.222
H72 Perforation of tympanic membrane	0.777	0.223
S64.4 Injury of digital nerve of other finger	0.777	0.223
H66 Suppurative and unspecified otitis media	0.775	0.225
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.772	0.228
T85.2 Mechanical complication of intraocular lens	0.771	0.229
I07 Rheumatic tricuspid valve diseases	0.769	0.231
Q50-Q56 Congenital malformations of genital organs	0.768	0.232
H90 Conductive and sensorineural hearing loss	0.766	0.234
B00 Herpesviral [herpes simplex] infections	0.765	0.235
H83 Other diseases of inner ear	0.763	0.237
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.761	0.239
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.758	0.242
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.755	0.245
H69 Other disorders of Eustachian tube	0.754	0.246
Y46 Antiepileptics and anti-Parkinsonism drugs	0.754	0.246
A50-A64 Infections with a predominantly sexual mode of transmission	0.753	0.247
T00-T07 Injuries involving multiple body regions	0.752	0.247
Y83.3 Surgical operation with formation of external stoma	0.752	0.248
A41.8 Other specified septicaemia	0.752	0.248
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.751	0.249
W50-W64 Exposure to animate mechanical forces	0.751	0.249
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.751	0.249
Q00-Q07 Congenital malformations of the nervous system	0.750	0.250
S72.1 Pertrochanteric fracture	0.750	0.250
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.749	0.250
B99-B99 Other infectious diseases	0.749	0.251
I74.9 Embolism and thrombosis of unspecified artery	0.748	0.252
B50-B64 Protozoal diseases	0.748	0.252
R22.3 Localised swelling, mass and lump, upper limb	0.748	0.252
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.748	0.252
B65-B83 Helminthiases	0.744	0.256
A40 Streptococcal septicaemia	0.744	0.256
T91 Sequelae of injuries of neck and trunk	0.744	0.256
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.744	0.256
R22.2 Localised swelling, mass and lump, trunk	0.744	0.256
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.743	0.257
Y40 Systemic antibiotics	0.742	0.258
E21.0 Primary hyperparathyroidism	0.741	0.259
R22.9 Localised swelling, mass and lump, unspecified	0.740	0.260
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.740	0.260
S79 Other and unspecified injuries of hip and thigh	0.740	0.260
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.739	0.261
T78 Adverse effects, not elsewhere classified	0.739	0.261
I70 Atherosclerosis	0.738	0.262
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.738	0.262
W20-W49 Exposure to inanimate mechanical forces	0.737	0.263
V40-V49 Car occupant injured in transport accident	0.737	0.263
T79-T79 Certain early complications of trauma	0.737	0.263
I08.0 Disorders of both mitral and aortic valves	0.732	0.268
S65 Injury of blood vessels at wrist and hand level	0.732	0.268
A41.0 Septicaemia due to Staphylococcus aureus	0.732	0.268
I77.0 Arteriovenous fistula, acquired	0.730	0.270
Chapter XXII Codes for special purposes	0.729	0.271
E23 Hypofunction and other disorders of pituitary gland	0.729	0.271
I78 Diseases of capillaries	0.728	0.272
H61.8 Other specified disorders of external ear	0.728	0.272
R27.8 Other and unspecified lack of coordination	0.726	0.274
B02 Zoster [herpes zoster]	0.725	0.275
R92 Abnormal findings on diagnostic imaging of breast	0.725	0.275
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.724	0.276
B18 Chronic viral hepatitis	0.723	0.277
H83.0 Labyrinthitis	0.722	0.278
H92.0 Otalgia	0.721	0.279
A41.5 Septicaemia due to other Gram-negative organisms	0.720	0.280
S29 Other and unspecified injuries of thorax	0.720	0.280
B97 Viral agents as the cause of diseases classified to other chapters	0.719	0.281
S69 Other and unspecified injuries of wrist and hand	0.719	0.281
E61 Deficiency of other nutrient elements	0.718	0.282
I73.8 Other specified peripheral vascular diseases	0.717	0.283
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283
A75-A79 Rickettsioses	0.717	0.283
A70-A74 Other diseases caused by chlamydiae	0.717	0.283
A65-A69 Other spirochaetal diseases	0.717	0.283
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283
A15-A19 Tuberculosis	0.717	0.283
B90-B94 Sequelae of infectious and parasitic diseases	0.717	0.283
X10-X19 Contact with heat and hot substances	0.716	0.284
Y00-Y09 Assault	0.715	0.284
T14.0 Superficial injury of unspecified body region	0.715	0.285
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.713	0.286
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.713	0.287
A87 Viral meningitis	0.712	0.288
I00-I02 Acute rheumatic fever	0.711	0.289
R23 Other skin changes	0.711	0.289
I77.8 Other specified disorders of arteries and arterioles	0.710	0.290
I77.5 Necrosis of artery	0.710	0.290
I77.4 Coeliac artery compression syndrome	0.710	0.290
I77.3 Arterial fibromuscular dysplasia	0.710	0.290
I77.2 Rupture of artery	0.710	0.290
S66 Injury of muscle and tendon at wrist and hand level	0.710	0.290
T85.4 Mechanical complication of breast prosthesis and implant	0.708	0.292
H61.0 Perichondritis of external ear	0.708	0.292
S20 Superficial injury of thorax	0.708	0.292
S61.1 Open wound of finger(s) with damage to nail	0.707	0.293
H94 Other disorders of ear in diseases classified elsewhere	0.706	0.294
R95-R99 Ill-defined and unknown causes of mortality	0.706	0.294
Y48 Anaesthetics and therapeutic gases	0.706	0.294
I27 Other pulmonary heart diseases	0.705	0.295
Y49 Psychotropic drugs, not elsewhere classified	0.705	0.295
Y52 Agents primarily affecting the cardiovascular system	0.704	0.296
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.704	0.296
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.704	0.296
I74.0 Embolism and thrombosis of abdominal aorta	0.704	0.296
H74 Other disorders of middle ear and mastoid	0.704	0.296
T18 Foreign body in alimentary tract	0.701	0.299
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.698	0.302
Y10-Y34 Event of undetermined intent	0.698	0.302
X85-X99 Assault	0.698	0.302
X58-X59 Accidental exposure to other and unspecified factors	0.698	0.302
X30-X39 Exposure to forces of nature	0.698	0.302
X00-X09 Exposure to smoke, fire and flames	0.698	0.302
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.698	0.302
W75-W84 Other accidental threats to breathing	0.698	0.302
W65-W74 Accidental drowning and submersion	0.698	0.302
V98-V99 Other and unspecified transport accidents	0.698	0.302
V95-V97 Air and space transport accidents	0.698	0.302
V90-V94 Water transport accidents	0.698	0.302
V70-V79 Bus occupant injured in transport accident	0.698	0.302
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.698	0.302
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.698	0.302
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.698	0.302
V01-V09 Pedestrian injured in transport accident	0.698	0.302
S70 Superficial injury of hip and thigh	0.698	0.302
R20.3 Hyperaesthesia	0.698	0.302
R20.1 Hypoaesthesia of skin	0.698	0.302
R20.0 Anaesthesia of skin	0.698	0.302
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.695	0.305
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.695	0.305
S10-S19 Injuries to the neck	0.695	0.305
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.694	0.306
T82.4 Mechanical complication of vascular dialysis catheter	0.694	0.306
X40-X49 Accidental poisoning by and exposure to noxious substances	0.693	0.307
T92 Sequelae of injuries of upper limb	0.692	0.308
B20-B24 Human immunodeficiency virus [HIV] disease	0.688	0.312
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.688	0.312
S40-S49 Injuries to the shoulder and upper arm	0.687	0.313
H93.9 Disorder of ear, unspecified	0.687	0.313
H93.8 Other specified disorders of ear	0.687	0.313
H93.3 Disorders of acoustic nerve	0.687	0.313
H93.2 Other abnormal auditory perceptions	0.687	0.313
H93.0 Degenerative and vascular disorders of ear	0.687	0.313
S72.2 Subtrochanteric fracture	0.687	0.313
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.685	0.315
E21.3 Hyperparathyroidism, unspecified	0.685	0.315
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.684	0.316
T87.6 Other and unspecified complications of amputation stump	0.684	0.316
H70 Mastoiditis and related conditions	0.683	0.317
Chapter VI Diseases of the nervous system	0.683	0.317
S60 Superficial injury of wrist and hand	0.682	0.318
Y53 Agents primarily affecting the gastro-intestinal system	0.681	0.319
T82.0 Mechanical complication of heart valve prosthesis	0.680	0.320
R42 Dizziness and giddiness	0.680	0.320
R93.6 Abnormal findings on diagnostic imaging of limbs	0.679	0.321
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.679	0.321
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.677	0.322
T83.2 Mechanical complication of graft of urinary organ	0.677	0.322
T78.3 Angioneurotic oedema	0.676	0.323
V20-V29 Motorcycle rider injured in transport accident	0.676	0.324
S72.10 Pertrochanteric fracture (closed)	0.676	0.324
T83.1 Mechanical complication of other urinary devices and implants	0.675	0.325
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.675	0.325
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.673	0.326
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.673	0.327
B06 Rubella [German measles]	0.673	0.327
B05 Measles	0.673	0.327
B01 Varicella [chickenpox]	0.673	0.327
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.673	0.327
B04 Monkeypox	0.673	0.327
B03 Smallpox	0.673	0.327
E27 Other disorders of adrenal gland	0.671	0.329
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.670	0.330
H68 Eustachian salpingitis and obstruction	0.670	0.330
H67 Otitis media in diseases classified elsewhere	0.670	0.330
R25 Abnormal involuntary movements	0.670	0.330
T88 Other complications of surgical and medical care, not elsewhere classified	0.669	0.331
A41.1 Septicaemia due to other specified staphylococcus	0.669	0.331
S72.4 Fracture of lower end of femur	0.668	0.332
S78 Traumatic amputation of hip and thigh	0.667	0.333
S77 Crushing injury of hip and thigh	0.667	0.333
S76 Injury of muscle and tendon at hip and thigh level	0.667	0.333
S75 Injury of blood vessels at hip and thigh level	0.667	0.333
S74 Injury of nerves at hip and thigh level	0.667	0.333
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.667	0.333
S71 Open wound of hip and thigh	0.667	0.333
D70-D77 Other diseases of blood and blood-forming organs	0.667	0.333
H65.9 Nonsuppurative otitis media, unspecified	0.667	0.333
X23 Contact with hornets, wasps and bees	0.665	0.335
B17 Other acute viral hepatitis	0.664	0.335
E20 Hypoparathyroidism	0.664	0.336
H65.0 Acute serous otitis media	0.664	0.336
X50 Overexertion and strenuous or repetitive movements	0.663	0.336
B34.8 Other viral infections of unspecified site	0.663	0.337
Q80-Q89 Other congenital malformations	0.663	0.337
I05 Rheumatic mitral valve diseases	0.663	0.337
X60-X84 Intentional self-harm	0.663	0.337
S64.1 Injury of median nerve at wrist and hand level	0.662	0.337
H90.5 Sensorineural hearing loss, unspecified	0.662	0.338
I07.1 Tricuspid insufficiency	0.662	0.338
R26 Abnormalities of gait and mobility	0.662	0.338
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.662	0.338
T83.0 Mechanical complication of urinary (indwelling) catheter	0.661	0.339
S51 Open wound of forearm	0.661	0.339
Y54.3 Benzothiadiazine derivatives	0.661	0.339
I09 Other rheumatic heart diseases	0.659	0.341
I06 Rheumatic aortic valve diseases	0.659	0.341
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.658	0.342
V10-V19 Pedal cyclist injured in transport accident	0.657	0.343
I73.1 Thromboangiitis obliterans [Buerger]	0.657	0.343
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.655	0.345
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.655	0.345
H65.4 Other chronic nonsuppurative otitis media	0.654	0.346
Q05 Spina bifida	0.653	0.347
B35-B49 Mycoses	0.653	0.347
H95.1 Other disorders following mastoidectomy	0.653	0.347
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.652	0.348
A00-A09 Intestinal infectious diseases	0.652	0.348
B33 Other viral diseases, not elsewhere classified	0.651	0.348
B30 Viral conjunctivitis	0.651	0.348
B27 Infectious mononucleosis	0.651	0.348
B26 Mumps	0.651	0.348
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.651	0.348
Y83.9 Surgical procedure, unspecified	0.651	0.349
Q51 Congenital malformations of uterus and cervix	0.651	0.349
E40-E46 Malnutrition	0.651	0.349
Y54.8 Agents affecting uric acid metabolism	0.651	0.349
A48 Other bacterial diseases, not elsewhere classified	0.651	0.349
R45 Symptoms and signs involving emotional state	0.651	0.349
Y59 Other and unspecified vaccines and biological substances	0.650	0.350
Y58 Bacterial vaccines	0.650	0.350
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.650	0.350
Y50 Central nervous system stimulants, not elsewhere classified	0.650	0.350
Y47 Sedatives, hypnotics and antianxiety drugs	0.650	0.350
I08.2 Disorders of both aortic and tricuspid valves	0.649	0.350
I72.4 Aneurysm of artery of lower extremity	0.649	0.351
Y60.0 During surgical operation	0.649	0.351
T90 Sequelae of injuries of head	0.649	0.351
V80-V89 Other land transport accidents	0.648	0.351
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.648	0.352
T86 Failure and rejection of transplanted organs and tissues	0.645	0.355
Y57 Other and unspecified drugs and medicaments	0.644	0.356
Y54.5 Other diuretics	0.644	0.356
A44 Bartonellosis	0.643	0.357
A43 Nocardiosis	0.643	0.357
A42 Actinomycosis	0.643	0.357
A39 Meningococcal infection	0.643	0.357
A37 Whooping cough	0.643	0.357
A36 Diphtheria	0.643	0.357
A32 Listeriosis	0.643	0.357
A31 Infection due to other mycobacteria	0.643	0.357
A30 Leprosy [Hansen's disease]	0.643	0.357
A38 Scarlet fever	0.643	0.357
A35 Other tetanus	0.643	0.357
A34 Obstetrical tetanus	0.643	0.357
A33 Tetanus neonatorum	0.643	0.357
S90-S99 Injuries to the ankle and foot	0.641	0.358
R22.0 Localised swelling, mass and lump, head	0.641	0.359
B25 Cytomegaloviral disease	0.640	0.359
H66.3 Other chronic suppurative otitis media	0.640	0.360
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.640	0.360
R72 Abnormality of white blood cells, not elsewhere classified	0.639	0.361
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.638	0.362
S61.8 Open wound of other parts of wrist and hand	0.638	0.362
H92.1 Otorrhoea	0.638	0.362
Y83.5 Amputation of limb(s)	0.636	0.364
T82.3 Mechanical complication of other vascular grafts	0.636	0.364
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.636	0.364
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.636	0.364
T87.4 Infection of amputation stump	0.636	0.364
T80 Complications following infusion, transfusion and therapeutic injection	0.635	0.365
T17 Foreign body in respiratory tract	0.635	0.365
T13 Other injuries of lower limb, level unspecified	0.635	0.365
S64.9 Injury of unspecified nerve at wrist and hand level	0.634	0.365
S64.8 Injury of other nerves at wrist and hand level	0.634	0.365
S64.7 Injury of multiple nerves at wrist and hand level	0.634	0.365
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.634	0.366
Q35-Q37 Cleft lip and cleft palate	0.634	0.366
Q30-Q34 Congenital malformations of the respiratory system	0.634	0.366
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.634	0.366
T20 Burn and corrosion of head and neck	0.634	0.366
I77.6 Arteritis, unspecified	0.633	0.367
S29.9 Unspecified injury of thorax	0.632	0.368
E00-E07 Disorders of thyroid gland	0.632	0.368
H72.8 Other perforations of tympanic membrane	0.632	0.368
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.630	0.370
T23 Burn and corrosion of wrist and hand	0.629	0.371
E24 Cushing's syndrome	0.629	0.371
S72.3 Fracture of shaft of femur	0.628	0.371
E64 Sequelae of malnutrition and other nutritional deficiencies	0.628	0.372
E63 Other nutritional deficiencies	0.628	0.372
E56 Other vitamin deficiencies	0.628	0.372
E51 Thiamine deficiency	0.628	0.372
E50 Vitamin A deficiency	0.628	0.372
E60 Dietary zinc deficiency	0.628	0.372
E59 Dietary selenium deficiency	0.628	0.372
E58 Dietary calcium deficiency	0.628	0.372
E54 Ascorbic acid deficiency	0.628	0.372
E52 Niacin deficiency [pellagra]	0.628	0.372
H62 Disorders of external ear in diseases classified elsewhere	0.628	0.372
T11 Other injuries of upper limb, level unspecified	0.627	0.373
T09 Other injuries of spine and trunk, level unspecified	0.627	0.373
T12.X1 Fracture of lower limb, level unspecified (open)	0.627	0.373
T12.X0 Fracture of lower limb, level unspecified (closed)	0.627	0.373
T12 Fracture of lower limb, level unspecified	0.627	0.373
T10.X1 Fracture of upper limb, level unspecified (open)	0.627	0.373
T10.X0 Fracture of upper limb, level unspecified (closed)	0.627	0.373
T10 Fracture of upper limb, level unspecified	0.627	0.373
T08.X1 Fracture of spine, level unspecified (open)	0.627	0.373
T08.X0 Fracture of spine, level unspecified (closed)	0.627	0.373
T08 Fracture of spine, level unspecified	0.627	0.373
R76 Other abnormal immunological findings in serum	0.627	0.373
H61.1 Non-infective disorders of pinna	0.626	0.373
I72.0 Aneurysm of carotid artery	0.626	0.374
R22.7 Localised swelling, mass and lump, multiple sites	0.626	0.374
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.626	0.374
A87.9 Viral meningitis, unspecified	0.626	0.374
T39.0 Salicylates	0.626	0.374
E55 Vitamin D deficiency	0.625	0.375
B00.9 Herpesviral infection, unspecified	0.624	0.376
T98 Sequelae of other and unspecified effects of external causes	0.623	0.377
T95 Sequelae of burns, corrosions and frostbite	0.623	0.377
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.623	0.377
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.623	0.377
Y83.0 Surgical operation with transplant of whole organ	0.622	0.378
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.622	0.378
B16 Acute hepatitis B	0.622	0.378
T94 Sequelae of injuries involving multiple and unspecified body regions	0.620	0.380
G00-G09 Inflammatory diseases of the central nervous system	0.620	0.380
S50 Superficial injury of forearm	0.617	0.382
W22 Striking against or struck by other objects	0.617	0.383
E34 Other endocrine disorders	0.616	0.384
E35 Disorders of endocrine glands in diseases classified elsewhere	0.615	0.385
E32 Diseases of thymus	0.615	0.385
E31 Polyglandular dysfunction	0.615	0.385
E30 Disorders of puberty, not elsewhere classified	0.615	0.385
E25 Adrenogenital disorders	0.615	0.385
A40.8 Other streptococcal septicaemia	0.614	0.386
H65.2 Chronic serous otitis media	0.614	0.386
H69.9 Eustachian tube disorder, unspecified	0.614	0.386
Chapter VII Diseases of the eye and adnexa	0.614	0.386
B19 Unspecified viral hepatitis	0.613	0.386
H61.9 Disorder of external ear, unspecified	0.612	0.388
I28 Other diseases of pulmonary vessels	0.612	0.388
H91 Other hearing loss	0.612	0.388
E10-E14 Diabetes mellitus	0.612	0.388
T81 Complications of procedures, not elsewhere classified	0.612	0.388
S72.9 Fracture of femur, part unspecified	0.611	0.388
S72.8 Fractures of other parts of femur	0.611	0.388
S72.7 Multiple fractures of femur	0.611	0.388
Q20-Q28 Congenital malformations of the circulatory system	0.611	0.389
S80-S89 Injuries to the knee and lower leg	0.611	0.389
I27.0 Primary pulmonary hypertension	0.611	0.389
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.610	0.390
H66.1 Chronic tubotympanic suppurative otitis media	0.609	0.391
B15 Acute hepatitis A	0.609	0.391
Y46.4 Iminostilbenes	0.607	0.392
B34.4 Papovirus infection, unspecified	0.607	0.393
B34.3 Parvovirus infection, unspecified	0.607	0.393
B34.2 Coronavirus infection, unspecified	0.607	0.393
B34.1 Enterovirus infection, unspecified	0.607	0.393
B34.0 Adenovirus infection, unspecified	0.607	0.393
Y51 Drugs primarily affecting the autonomic nervous system	0.605	0.395
E61.1 Iron deficiency	0.604	0.396
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.604	0.396
S26 Injury of heart	0.604	0.396
S25 Injury of blood vessels of thorax	0.604	0.396
S24 Injury of nerves and spinal cord at thorax level	0.604	0.396
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.604	0.396
S21 Open wound of thorax	0.604	0.396
A41.4 Septicaemia due to anaerobes	0.604	0.396
A41.3 Septicaemia due to Haemophilus influenzae	0.604	0.396
G40-G47 Episodic and paroxysmal disorders	0.604	0.396
Y41 Other systemic anti-infectives and antiparasitics	0.603	0.397
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.603	0.397
Y45.0 Opioids and related analgesics	0.603	0.397
H92.2 Otorrhagia	0.603	0.397
S79.9 Unspecified injury of hip and thigh	0.603	0.397
E26 Hyperaldosteronism	0.601	0.399
S64.2 Injury of radial nerve at wrist and hand level	0.601	0.399
I27.9 Pulmonary heart disease, unspecified	0.601	0.399
Y83.1 Surgical operation with implant of artificial internal device	0.601	0.399
T75 Effects of other external causes	0.601	0.399
T74 Maltreatment syndromes	0.601	0.399
T73 Effects of other deprivation	0.601	0.399
T70 Effects of air pressure and water pressure	0.601	0.399
T69 Other effects of reduced temperature	0.601	0.399
T67 Effects of heat and light	0.601	0.399
T71 Asphyxiation	0.601	0.399
T66 Unspecified effects of radiation	0.601	0.399
S20.2 Contusion of thorax	0.601	0.399
T19 Foreign body in genito-urinary tract	0.601	0.399
T15 Foreign body on external eye	0.601	0.399

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations