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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62328524
log Bayes Factor = 13.1701
Chromosome 4   position 161,682,941  (GRCh37) Explore rs62328524 on Ensembl!
Variant rs62328524 is part of Cluster X0284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
I10 Essential (primary) hypertension
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
H65-H75 Diseases of middle ear and mastoid
0.991 0.009 0.000
H40-H42 Glaucoma
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
J44 Other chronic obstructive pulmonary disease
0.984 0.016 0.000
H40 Glaucoma
0.984 0.016 0.000
J40-J47 Chronic lower respiratory diseases
0.983 0.017 0.000
H40.9 Glaucoma, unspecified
0.981 0.019 0.000
I05-I09 Chronic rheumatic heart diseases
0.980 0.020 0.000
I51 Complications and ill-defined descriptions of heart disease
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.968 0.032 0.000
I60-I69 Cerebrovascular diseases
0.968 0.032 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.958 0.042 0.000
I50 Heart failure
0.955 0.045 0.000
I49 Other cardiac arrhythmias
0.950 0.050 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.947 0.053 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.946 0.054 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.945 0.055 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.944 0.056 0.000
J00-J06 Acute upper respiratory infections
0.944 0.056 0.000
O60-O75 Complications of labour and delivery
0.941 0.059 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
I46 Cardiac arrest
0.937 0.063 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.933 0.067 0.000
I35 Nonrheumatic aortic valve disorders
0.930 0.070 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.925 0.075 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.922 0.078 0.000
H71 Cholesteatoma of middle ear
0.922 0.078 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.921 0.079 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.919 0.081 0.000
I51.9 Heart disease, unspecified
0.917 0.083 0.000
H60-H62 Diseases of external ear
0.916 0.084 0.000
F17.2 Dependence syndrome
0.914 0.086 0.000
H74 Other disorders of middle ear and mastoid
0.913 0.087 0.000
J03 Acute tonsillitis
0.911 0.089 0.000
H65 Nonsuppurative otitis media
0.908 0.092 0.000
I46.9 Cardiac arrest, unspecified
0.908 0.092 0.000
F40 Phobic anxiety disorders
0.906 0.094 0.000
I26 Pulmonary embolism
0.895 0.105 0.000
I07 Rheumatic tricuspid valve diseases
0.892 0.108 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.892 0.108 0.000
H33 Retinal detachments and breaks
0.892 0.108 0.000
J03.9 Acute tonsillitis, unspecified
0.888 0.112 0.000
F40.2 Specific (isolated) phobias
0.887 0.113 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.884 0.116 0.000
I50.0 Congestive heart failure
0.884 0.116 0.000
I34 Nonrheumatic mitral valve disorders
0.883 0.117 0.000
H55-H59 Other disorders of eye and adnexa
0.883 0.117 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.882 0.118 0.000
I50.9 Heart failure, unspecified
0.881 0.119 0.000
I08 Multiple valve diseases
0.879 0.121 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.878 0.122 0.000
I51.7 Cardiomegaly
0.872 0.128 0.000
M45-M49 Spondylopathies
0.872 0.128 0.000
I71 Aortic aneurysm and dissection
0.871 0.129 0.000
I35.0 Aortic (valve) stenosis
0.871 0.129 0.000
M05-M14 Inflammatory polyarthropathies
0.871 0.129 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.866 0.134 0.000
I49.8 Other specified cardiac arrhythmias
0.861 0.139 0.000
I74 Arterial embolism and thrombosis
0.861 0.139 0.000
H74.0 Tympanosclerosis
0.860 0.140 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.858 0.142 0.000
I05 Rheumatic mitral valve diseases
0.856 0.144 0.000
O66 Other obstructed labour
0.855 0.145 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.853 0.147 0.000
H61 Other disorders of external ear
0.851 0.149 0.000
W00-W19 Falls
0.848 0.152 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.848 0.152 0.000
H36 Retinal disorders in diseases classified elsewhere
0.846 0.154 0.000
M13 Other arthritis
0.845 0.155 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.844 0.156 0.000
I51.0 Cardiac septal defect, acquired
0.835 0.165 0.000
J43 Emphysema
0.833 0.167 0.000
I07.1 Tricuspid insufficiency
0.830 0.170 0.000
H33.2 Serous retinal detachment
0.829 0.171 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.824 0.176 0.000
M13.9 Arthritis, unspecified
0.820 0.180 0.000
Y95 Nosocomial condition
0.818 0.182 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.817 0.183 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.817 0.183 0.000
H35 Other retinal disorders
0.811 0.189 0.000
X60-X84 Intentional self-harm
0.809 0.191 0.000
I77 Other disorders of arteries and arterioles
0.809 0.191 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.804 0.196 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.801 0.199 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.800 0.199 0.000
Y84.0 Cardiac catheterisation
0.800 0.200 0.000
F43 Reaction to severe stress, and adjustment disorders
0.799 0.201 0.000
M45 Ankylosing spondylitis
0.797 0.203 0.000
H66 Suppurative and unspecified otitis media
0.797 0.203 0.000
H10-H13 Disorders of conjunctiva
0.795 0.205 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.793 0.207 0.000
H40.0 Glaucoma suspect
0.793 0.207 0.000
I49.3 Ventricular premature depolarisation
0.791 0.209 0.000
I72 Other aneurysm
0.790 0.210 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.787 0.213 0.000
O85-O92 Complications predominantly related to the puerperium
0.786 0.214 0.000
I63 Cerebral infarction
0.785 0.215 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.784 0.216 0.000
Chapter II Neoplasms
0.782 0.218 0.000
H40.8 Other glaucoma
0.781 0.219 0.000
H90-H95 Other disorders of ear
0.781 0.219 0.000
O00-O08 Pregnancy with abortive outcome
0.781 0.219 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
I49.5 Sick sinus syndrome
0.779 0.221 0.000
H80-H83 Diseases of inner ear
0.777 0.223 0.000
I34.1 Mitral (valve) prolapse
0.776 0.224 0.000
I60 Subarachnoid haemorrhage
0.772 0.228 0.000
W50-W64 Exposure to animate mechanical forces
0.771 0.229 0.000
F60-F69 Disorders of adult personality and behaviour
0.768 0.232 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.765 0.235 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.763 0.237 0.000
I74.5 Embolism and thrombosis of iliac artery
0.763 0.237 0.000
I38 Endocarditis, valve unspecified
0.763 0.237 0.000
I49.9 Cardiac arrhythmia, unspecified
0.762 0.238 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.762 0.238 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.762 0.238 0.000
J95-J99 Other diseases of the respiratory system
0.760 0.240 0.000
H36.0 Diabetic retinopathy
0.759 0.241 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.759 0.241 0.000
H35.4 Peripheral retinal degeneration
0.758 0.242 0.000
M46 Other inflammatory spondylopathies
0.757 0.243 0.000
I45 Other conduction disorders
0.756 0.244 0.000
W20-W49 Exposure to inanimate mechanical forces
0.756 0.244 0.000
O80-O84 Delivery
0.756 0.244 0.000
H33.1 Retinoschisis and retinal cysts
0.755 0.245 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.754 0.246 0.000
H31 Other disorders of choroid
0.754 0.246 0.000
W13 Fall from, out of or through building or structure
0.753 0.247 0.000
I27 Other pulmonary heart diseases
0.752 0.248 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.752 0.248 0.000
I61 Intracerebral haemorrhage
0.751 0.249 0.000
Y44 Agents primarily affecting blood constituents
0.750 0.250 0.000
O62 Abnormalities of forces of labour
0.750 0.250 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.749 0.251 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.749 0.251 0.000
J02 Acute pharyngitis
0.746 0.254 0.000
Y48 Anaesthetics and therapeutic gases
0.744 0.256 0.000
M13.98 Arthritis, unspecified (Other)
0.744 0.256 0.000
Y84.6 Urinary catheterisation
0.741 0.259 0.000
Y54.3 Benzothiadiazine derivatives
0.741 0.259 0.000
I11 Hypertensive heart disease
0.740 0.260 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.738 0.262 0.000
H33.3 Retinal breaks without detachment
0.738 0.262 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.737 0.263 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.737 0.263 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.734 0.266 0.000
H61.0 Perichondritis of external ear
0.731 0.269 0.000
H65.2 Chronic serous otitis media
0.731 0.269 0.000
H40.5 Glaucoma secondary to other eye disorders
0.730 0.270 0.000
Q23 Congenital malformations of aortic and mitral valves
0.730 0.270 0.000
X50-X57 Overexertion, travel and privation
0.729 0.270 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.728 0.272 0.000
I15 Secondary hypertension
0.727 0.273 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.727 0.273 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.725 0.275 0.000
J43.9 Emphysema, unspecified
0.725 0.275 0.000
I70 Atherosclerosis
0.725 0.275 0.000
O04 Medical abortion
0.724 0.276 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.721 0.279 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.720 0.280 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.720 0.280 0.000
H69 Other disorders of Eustachian tube
0.719 0.281 0.000
O72 Postpartum haemorrhage
0.718 0.282 0.000
I05.2 Mitral stenosis with insufficiency
0.718 0.282 0.000
O61 Failed induction of labour
0.718 0.282 0.000
I37 Pulmonary valve disorders
0.717 0.282 0.000
J01 Acute sinusitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.716 0.284 0.000
O63 Long labour
0.716 0.284 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.713 0.287 0.000
Q50-Q56 Congenital malformations of genital organs
0.713 0.287 0.000
I62 Other nontraumatic intracranial haemorrhage
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
H61.2 Impacted cerumen
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
Y84.2 Radiological procedure and radiotherapy
0.711 0.289 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.710 0.289 0.000
H70 Mastoiditis and related conditions
0.710 0.289 0.000
H68 Eustachian salpingitis and obstruction
0.710 0.289 0.000
H67 Otitis media in diseases classified elsewhere
0.710 0.289 0.000
I44 Atrioventricular and left bundle-branch block
0.710 0.290 0.000
H42 Glaucoma in diseases classified elsewhere
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
W17 Other fall from one level to another
0.708 0.292 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.707 0.293 0.000
C15-C26 Malignant neoplasms of digestive organs
0.706 0.294 0.000
Y52 Agents primarily affecting the cardiovascular system
0.706 0.294 0.000
H40.6 Glaucoma secondary to drugs
0.705 0.294 0.000
H40.4 Glaucoma secondary to eye inflammation
0.705 0.294 0.000
H40.3 Glaucoma secondary to eye trauma
0.705 0.294 0.000
J41 Simple and mucopurulent chronic bronchitis
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.704 0.296 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.704 0.296 0.000
I49.1 Atrial premature depolarisation
0.704 0.296 0.000
I09 Other rheumatic heart diseases
0.703 0.297 0.000
I06 Rheumatic aortic valve diseases
0.703 0.297 0.000
I51.6 Cardiovascular disease, unspecified
0.702 0.297 0.000
I51.5 Myocardial degeneration
0.702 0.297 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.702 0.297 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.702 0.297 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.702 0.297 0.000
I63.9 Cerebral infarction, unspecified
0.703 0.297 0.000
M91-M94 Chondropathies
0.702 0.297 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
H61.9 Disorder of external ear, unspecified
0.700 0.300 0.000
I35.8 Other aortic valve disorders
0.700 0.300 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.699 0.301 0.000
M60-M63 Disorders of muscles
0.698 0.301 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.698 0.302 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.696 0.304 0.000
F70-F79 Mental retardation
0.696 0.304 0.000
M48 Other spondylopathies
0.695 0.305 0.000
I51.4 Myocarditis, unspecified
0.695 0.305 0.000
H90 Conductive and sensorineural hearing loss
0.694 0.306 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.694 0.306 0.000
H30 Chorioretinal inflammation
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.694 0.306 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.694 0.306 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.693 0.307 0.000
I08.8 Other multiple valve diseases
0.691 0.309 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.690 0.310 0.000
I34.0 Mitral (valve) insufficiency
0.689 0.311 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.688 0.312 0.000
J09-J18 Influenza and pneumonia
0.688 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.686 0.313 0.000
I63.8 Other cerebral infarction
0.686 0.314 0.000
W13.9 Unspecified place
0.685 0.315 0.000
C71 Malignant neoplasm of brain
0.685 0.315 0.000
I74.8 Embolism and thrombosis of other arteries
0.684 0.316 0.000
H60 Otitis externa
0.683 0.317 0.000
H11 Other disorders of conjunctiva
0.682 0.318 0.000
I77.6 Arteritis, unspecified
0.682 0.318 0.000
I49.2 Junctional premature depolarisation
0.681 0.319 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.681 0.319 0.000
I71.0 Dissection of aorta [any part]
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.319 0.000
J04 Acute laryngitis and tracheitis
0.680 0.320 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.680 0.320 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.680 0.320 0.000
Q23.1 Congenital insufficiency of aortic valve
0.680 0.320 0.000
I36 Nonrheumatic tricuspid valve disorders
0.679 0.321 0.000
J20-J22 Other acute lower respiratory infections
0.679 0.321 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.679 0.321 0.000
I28 Other diseases of pulmonary vessels
0.679 0.321 0.000
I08.0 Disorders of both mitral and aortic valves
0.678 0.322 0.000
M10 Gout
0.677 0.323 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.677 0.323 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.677 0.323 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.677 0.323 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.677 0.323 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.677 0.323 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.677 0.323 0.000
F11 Mental and behavioural disorders due to use of opioids
0.677 0.323 0.000
I51.8 Other ill-defined heart diseases
0.677 0.323 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.325 0.000
O74 Complications of anaesthesia during labour and delivery
0.675 0.325 0.000
O71 Other obstetric trauma
0.675 0.325 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.675 0.325 0.000
O60 Preterm delivery
0.675 0.325 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.674 0.326 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
H72 Perforation of tympanic membrane
0.672 0.328 0.000
I46.1 Sudden cardiac death, so described
0.672 0.328 0.000
H40.1 Primary open-angle glaucoma
0.670 0.330 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
F48 Other neurotic disorders
0.669 0.331 0.000
F44 Dissociative [conversion] disorders
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.668 0.332 0.000
I05.0 Mitral stenosis
0.667 0.333 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.666 0.334 0.000
H55 Nystagmus and other irregular eye movements
0.665 0.335 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.664 0.336 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.663 0.336 0.000
O04.9 Complete or unspecified, without complication
0.663 0.336 0.000
Y59 Other and unspecified vaccines and biological substances
0.663 0.337 0.000
Y58 Bacterial vaccines
0.663 0.337 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.663 0.337 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.663 0.337 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.663 0.337 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.663 0.337 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.663 0.337 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.663 0.337 0.000
Y57 Other and unspecified drugs and medicaments
0.663 0.337 0.000
I78 Diseases of capillaries
0.662 0.338 0.000
M13.0 Polyarthritis, unspecified
0.662 0.338 0.000
H43-H45 Disorders of vitreous body and globe
0.662 0.338 0.000
F17.9 Unspecified mental and behavioural disorder
0.661 0.339 0.000
F17.8 Other mental and behavioural disorders
0.661 0.339 0.000
F17.7 Residual and late-onset psychotic disorder
0.661 0.339 0.000
F17.6 Amnesic syndrome
0.661 0.339 0.000
F17.5 Psychotic disorder
0.661 0.339 0.000
F17.4 Withdrawal state with delirium
0.661 0.339 0.000
F17.3 Withdrawal state
0.661 0.339 0.000
F17.0 Acute intoxication
0.661 0.339 0.000
Y40 Systemic antibiotics
0.661 0.339 0.000
H57 Other disorders of eye and adnexa
0.661 0.339 0.000
H66.3 Other chronic suppurative otitis media
0.659 0.341 0.000
M00-M03 Infectious arthropathies
0.659 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.341 0.000
M05 Seropositive rheumatoid arthritis
0.658 0.342 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.657 0.343 0.000
F42 Obsessive-compulsive disorder
0.657 0.343 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.657 0.343 0.000
I35.9 Aortic valve disorder, unspecified
0.657 0.343 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.655 0.345 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.655 0.345 0.000
M86-M90 Other osteopathies
0.655 0.345 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.655 0.345 0.000
H74.1 Adhesive middle ear disease
0.655 0.345 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
J98 Other respiratory disorders
0.654 0.346 0.000
I73 Other peripheral vascular diseases
0.654 0.346 0.000
I05.9 Mitral valve disease, unspecified
0.654 0.346 0.000
I27.2 Other secondary pulmonary hypertension
0.654 0.346 0.000
I30 Acute pericarditis
0.654 0.346 0.000
O30 Multiple gestation
0.654 0.346 0.000
Y43 Primarily systemic agents
0.653 0.346 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.653 0.347 0.000
J03.0 Streptococcal tonsillitis
0.653 0.347 0.000
O41 Other disorders of amniotic fluid and membranes
0.653 0.347 0.000
I60.8 Other subarachnoid haemorrhage
0.653 0.347 0.000
F43.2 Adjustment disorders
0.653 0.347 0.000
H65.1 Other acute nonsuppurative otitis media
0.651 0.349 0.000
H65.0 Acute serous otitis media
0.651 0.349 0.000
J46 Status asthmaticus
0.651 0.349 0.000
F40.9 Phobic anxiety disorder, unspecified
0.650 0.350 0.000
F40.8 Other phobic anxiety disorders
0.650 0.350 0.000
F40.1 Social phobias
0.650 0.350 0.000
F40.0 Agoraphobia
0.650 0.350 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
H73 Other disorders of tympanic membrane
0.648 0.352 0.000
O46.9 Antepartum haemorrhage, unspecified
0.646 0.354 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.646 0.354 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.645 0.355 0.000
H35.6 Retinal haemorrhage
0.644 0.356 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.644 0.356 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.643 0.357 0.000
I45.1 Other and unspecified right bundle-branch block
0.642 0.358 0.000
Q80-Q89 Other congenital malformations
0.642 0.358 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.642 0.358 0.000
O82 Single delivery by Caesarean section
0.642 0.358 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.641 0.359 0.000
H46 Optic neuritis
0.641 0.359 0.000
I07.9 Tricuspid valve disease, unspecified
0.640 0.360 0.000
I07.8 Other tricuspid valve diseases
0.640 0.360 0.000
I07.2 Tricuspid stenosis with insufficiency
0.640 0.360 0.000
I07.0 Tricuspid stenosis
0.640 0.360 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.639 0.361 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.639 0.361 0.000
Y98 Lifestyle-related condition
0.639 0.361 0.000
Y97 Environmental-pollution-related condition
0.639 0.361 0.000
Y96 Work-related condition
0.639 0.361 0.000
H33.4 Traction detachment of retina
0.639 0.361 0.000
I77.0 Arteriovenous fistula, acquired
0.638 0.361 0.000
H53-H54 Visual disturbances and blindness
0.637 0.363 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.636 0.364 0.000
I49.0 Ventricular fibrillation and flutter
0.636 0.364 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.633 0.367 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.633 0.367 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.633 0.367 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.632 0.367 0.000
O97 Death from sequelae of direct obstetric causes
0.632 0.367 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.632 0.367 0.000
O95 Obstetric death of unspecified cause
0.632 0.367 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.632 0.367 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.631 0.369 0.000
F45 Somatoform disorders
0.630 0.369 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.631 0.369 0.000
I08.9 Multiple valve disease, unspecified
0.630 0.369 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.630 0.369 0.000
H65.3 Chronic mucoid otitis media
0.630 0.370 0.000
M13.94 Arthritis, unspecified (Hand)
0.630 0.370 0.000
I72.8 Aneurysm of other specified arteries
0.630 0.370 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.629 0.371 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.627 0.373 0.000
Y44.2 Anticoagulants
0.625 0.375 0.000
M49 Spondylopathies in diseases classified elsewhere
0.625 0.375 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.624 0.375 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.624 0.375 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.624 0.375 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.624 0.375 0.000
M14 Arthropathies in other diseases classified elsewhere
0.624 0.376 0.000
M12 Other specific arthropathies
0.624 0.376 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.624 0.376 0.000
M08 Juvenile arthritis
0.624 0.376 0.000
Q65 Congenital deformities of hip
0.624 0.376 0.000
I33 Acute and subacute endocarditis
0.623 0.376 0.000
F64 Gender identity disorders
0.624 0.376 0.000
H35.5 Hereditary retinal dystrophy
0.623 0.377 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.622 0.378 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.622 0.378 0.000
O90 Complications of the puerperium, not elsewhere classified
0.621 0.379 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.379 0.000
O15 Eclampsia
0.621 0.379 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.621 0.379 0.000
F43.1 Posttraumatic stress disorder
0.621 0.379 0.000
I72.4 Aneurysm of artery of lower extremity
0.620 0.380 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.620 0.380 0.000
M65-M68 Disorders of synovium and tendon
0.620 0.380 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.619 0.381 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.618 0.382 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.618 0.382 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.617 0.383 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.617 0.383 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.617 0.383 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.617 0.383 0.000
J98.4 Other disorders of lung
0.617 0.383 0.000
O14.9 Preeclampsia, unspecified
0.616 0.383 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.615 0.384 0.000
H11.3 Conjunctival haemorrhage
0.614 0.385 0.000
Y48.3 Local anaesthetics
0.614 0.386 0.000
J47 Bronchiectasis
0.614 0.386 0.000
Q96 Turner's syndrome
0.613 0.386 0.000
I05.8 Other mitral valve diseases
0.613 0.386 0.000
I05.1 Rheumatic mitral insufficiency
0.613 0.386 0.000
H90.2 Conductive hearing loss, unspecified
0.613 0.387 0.000
O66.9 Obstructed labour, unspecified
0.613 0.387 0.000
O66.8 Other specified obstructed labour
0.613 0.387 0.000
O66.4 Failed trial of labour, unspecified
0.613 0.387 0.000
O66.3 Obstructed labour due to other abnormalities of foetus
0.613 0.387 0.000
O66.2 Obstructed labour due to unusually large foetus
0.613 0.387 0.000
O66.1 Obstructed labour due to locked twins
0.613 0.387 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.613 0.387 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.613 0.387 0.000
H61.1 Non-infective disorders of pinna
0.612 0.388 0.000
H80 Otosclerosis
0.611 0.389 0.000
O44 Placenta praevia
0.611 0.389 0.000
H61.3 Acquired stenosis of external ear canal
0.610 0.390 0.000
F43.0 Acute stress reaction
0.610 0.390 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.609 0.390 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.608 0.392 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.608 0.392 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.608 0.392 0.000
W15 Fall from cliff
0.608 0.392 0.000
W14 Fall from tree
0.608 0.392 0.000
W12 Fall on and from scaffolding
0.608 0.392 0.000
W11 Fall on and from ladder
0.608 0.392 0.000
W10 Fall on and from stairs and steps
0.608 0.392 0.000
W09 Fall involving playground equipment
0.608 0.392 0.000
W05 Fall involving wheelchair
0.608 0.392 0.000
W04 Fall while being carried or supported by other persons
0.608 0.392 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.608 0.392 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.608 0.392 0.000
W00 Fall on same level involving ice and snow
0.608 0.392 0.000
Y84.9 Medical procedure, unspecified
0.608 0.392 0.000
Y84.7 Blood-sampling
0.608 0.392 0.000
Y84.5 Insertion of gastric or duodenal sound
0.608 0.392 0.000
Y84.4 Aspiration of fluid
0.608 0.392 0.000
Y84.3 Shock therapy
0.608 0.392 0.000
H92 Otalgia and effusion of ear
0.608 0.392 0.000
W17.4 Street and highway
0.608 0.392 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.607 0.393 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.607 0.393 0.000
M13.8 Other specified arthritis
0.606 0.394 0.000
M13.1 Monoarthritis, not elsewhere classified
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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