TreeWAS – Variant ID: rs62449372

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
N17-N19 Renal failure	0.999	0.001	0.000
Chapter X Diseases of the respiratory system	0.999	0.001	0.000
Chapter XI Diseases of the digestive system	0.998	0.002	0.000
Chapter IX Diseases of the circulatory system	0.995	0.005	0.000
K70-K77 Diseases of liver	0.992	0.008	0.000
Chapter I Certain infectious and parasitic diseases	0.992	0.008	0.000
Chapter VII Diseases of the eye and adnexa	0.984	0.016	0.000
S60-S69 Injuries to the wrist and hand	0.982	0.018	0.000
Chapter II Neoplasms	0.976	0.024	0.000
N18 Chronic renal failure	0.975	0.025	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.975	0.025	0.000
J09-J18 Influenza and pneumonia	0.973	0.027	0.000
N10-N16 Renal tubulo-interstitial diseases	0.971	0.029	0.000
K70 Alcoholic liver disease	0.970	0.030	0.000
N17 Acute renal failure	0.968	0.032	0.000
Chapter V Mental and behavioural disorders	0.965	0.035	0.000
I30-I52 Other forms of heart disease	0.965	0.035	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.962	0.038	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.955	0.045	0.000
J18 Pneumonia, organism unspecified	0.947	0.053	0.000
N17.9 Acute renal failure, unspecified	0.946	0.054	0.000
I50 Heart failure	0.945	0.055	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.944	0.056	0.000
K35-K38 Diseases of appendix	0.944	0.056	0.000
Chapter VIII Diseases of the ear and mastoid process	0.943	0.057	0.000
Chapter XX External causes of morbidity and mortality	0.939	0.061	0.000
N13 Obstructive and reflux uropathy	0.937	0.063	0.000
H10-H13 Disorders of conjunctiva	0.934	0.066	0.000
N00-N08 Glomerular diseases	0.927	0.073	0.000
N18.3 Chronic kidney disease, stage 3	0.923	0.077	0.000
N19 Unspecified renal failure	0.923	0.077	0.000
J40-J47 Chronic lower respiratory diseases	0.923	0.077	0.000
J30-J39 Other diseases of upper respiratory tract	0.916	0.084	0.000
I50.9 Heart failure, unspecified	0.915	0.085	0.000
S61 Open wound of wrist and hand	0.908	0.092	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.908	0.092	0.000
N18.9 Chronic renal failure, unspecified	0.906	0.094	0.000
J20-J22 Other acute lower respiratory infections	0.906	0.094	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.903	0.097	0.000
C51-C58 Malignant neoplasms of female genital organs	0.902	0.098	0.000
K35 Acute appendicitis	0.902	0.098	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.901	0.099	0.000
H65-H75 Diseases of middle ear and mastoid	0.900	0.100	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.900	0.100	0.000
A30-A49 Other bacterial diseases	0.896	0.104	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.894	0.106	0.000
N20-N23 Urolithiasis	0.890	0.110	0.000
K70.9 Alcoholic liver disease, unspecified	0.886	0.114	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.879	0.121	0.000
K35.9 Acute appendicitis, unspecified	0.878	0.122	0.000
S90-S99 Injuries to the ankle and foot	0.878	0.122	0.000
H11 Other disorders of conjunctiva	0.878	0.122	0.000
N72 Inflammatory disease of cervix uteri	0.878	0.122	0.000
B95-B98 Bacterial, viral and other infectious agents	0.876	0.124	0.000
K40-K46 Hernia	0.876	0.124	0.000
I71 Aortic aneurysm and dissection	0.875	0.125	0.000
K72 Hepatic failure, not elsewhere classified	0.874	0.126	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.871	0.129	0.000
J18.1 Lobar pneumonia, unspecified	0.869	0.131	0.000
J32 Chronic sinusitis	0.869	0.131	0.000
I74 Arterial embolism and thrombosis	0.868	0.132	0.000
J18.9 Pneumonia, unspecified	0.867	0.133	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.865	0.135	0.000
Chapter XXII Codes for special purposes	0.865	0.135	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.861	0.139	0.000
S68 Traumatic amputation of wrist and hand	0.859	0.141	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.855	0.145	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.853	0.147	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.853	0.147	0.000
S80-S89 Injuries to the knee and lower leg	0.852	0.148	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.848	0.152	0.000
K70.3 Alcoholic cirrhosis of liver	0.848	0.152	0.000
J32.0 Chronic maxillary sinusitis	0.845	0.155	0.000
N99-N99 Other disorders of the genitourinary system	0.844	0.156	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.843	0.157	0.000
Chapter VI Diseases of the nervous system	0.842	0.158	0.000
S40-S49 Injuries to the shoulder and upper arm	0.840	0.160	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.840	0.160	0.000
I60-I69 Cerebrovascular diseases	0.837	0.163	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.836	0.164	0.000
B35-B49 Mycoses	0.836	0.164	0.000
J22 Unspecified acute lower respiratory infection	0.834	0.166	0.000
C34 Malignant neoplasm of bronchus and lung	0.834	0.166	0.000
C54 Malignant neoplasm of corpus uteri	0.833	0.167	0.000
J43 Emphysema	0.832	0.168	0.000
J34 Other disorders of nose and nasal sinuses	0.828	0.172	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.825	0.175	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.825	0.175	0.000
T39.1 4-Aminophenol derivatives	0.824	0.176	0.000
H43-H45 Disorders of vitreous body and globe	0.823	0.177	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.817	0.183	0.000
I20-I25 Ischaemic heart diseases	0.817	0.183	0.000
B15-B19 Viral hepatitis	0.815	0.185	0.000
I50.0 Congestive heart failure	0.815	0.185	0.000
N20 Calculus of kidney and ureter	0.812	0.188	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.812	0.188	0.000
K42 Umbilical hernia	0.811	0.189	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.810	0.190	0.000
K76 Other diseases of liver	0.809	0.191	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.805	0.195	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.805	0.195	0.000
I27 Other pulmonary heart diseases	0.805	0.195	0.000
K70.4 Alcoholic hepatic failure	0.803	0.197	0.000
N02 Recurrent and persistent haematuria	0.802	0.198	0.000
I38 Endocarditis, valve unspecified	0.800	0.200	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.798	0.202	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.798	0.202	0.000
I21 Acute myocardial infarction	0.796	0.204	0.000
F30-F39 Mood [affective] disorders	0.795	0.205	0.000
N76 Other inflammation of vagina and vulva	0.793	0.207	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.792	0.208	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.792	0.208	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.792	0.208	0.000
N03 Chronic nephritic syndrome	0.789	0.211	0.000
S61.0 Open wound of finger(s) without damage to nail	0.789	0.211	0.000
C81 Hodgkin's disease	0.788	0.212	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.786	0.214	0.000
C54.1 Endometrium	0.783	0.217	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.783	0.217	0.000
J34.3 Hypertrophy of nasal turbinates	0.783	0.217	0.000
H11.3 Conjunctival haemorrhage	0.782	0.218	0.000
K65-K67 Diseases of peritoneum	0.781	0.219	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.780	0.220	0.000
A41 Other septicaemia	0.780	0.220	0.000
K70.1 Alcoholic hepatitis	0.780	0.220	0.000
S61.1 Open wound of finger(s) with damage to nail	0.778	0.222	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.777	0.223	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.776	0.224	0.000
S82 Fracture of lower leg, including ankle	0.775	0.225	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.773	0.227	0.000
G90-G99 Other disorders of the nervous system	0.773	0.227	0.000
S60 Superficial injury of wrist and hand	0.772	0.228	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.772	0.228	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.772	0.228	0.000
H53-H54 Visual disturbances and blindness	0.771	0.229	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.771	0.229	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.771	0.229	0.000
C83.3 Large cell (diffuse)	0.771	0.229	0.000
F80-F89 Disorders of psychological development	0.770	0.230	0.000
J81 Pulmonary oedema	0.769	0.231	0.000
I35 Nonrheumatic aortic valve disorders	0.769	0.231	0.000
Y43 Primarily systemic agents	0.768	0.232	0.000
H72 Perforation of tympanic membrane	0.767	0.233	0.000
J40 Bronchitis, not specified as acute or chronic	0.767	0.233	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.767	0.233	0.000
I42 Cardiomyopathy	0.766	0.234	0.000
N18.2 Chronic kidney disease, stage 2	0.766	0.234	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.766	0.234	0.000
H10 Conjunctivitis	0.764	0.236	0.000
H66 Suppurative and unspecified otitis media	0.763	0.237	0.000
W20-W49 Exposure to inanimate mechanical forces	0.763	0.237	0.000
T79-T79 Certain early complications of trauma	0.762	0.238	0.000
H00 Hordeolum and chalazion	0.761	0.239	0.000
S70-S79 Injuries to the hip and thigh	0.760	0.240	0.000
K43 Ventral hernia	0.760	0.240	0.000
B65-B83 Helminthiases	0.760	0.240	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.759	0.241	0.000
S92 Fracture of foot, except ankle	0.758	0.242	0.000
J60-J70 Lung diseases due to external agents	0.756	0.244	0.000
I27.0 Primary pulmonary hypertension	0.756	0.244	0.000
S62 Fracture at wrist and hand level	0.755	0.245	0.000
K75 Other inflammatory liver diseases	0.753	0.247	0.000
D45 Polycythaemia vera	0.751	0.249	0.000
N73 Other female pelvic inflammatory diseases	0.749	0.251	0.000
K74 Fibrosis and cirrhosis of liver	0.748	0.251	0.000
J95-J99 Other diseases of the respiratory system	0.748	0.252	0.000
I33 Acute and subacute endocarditis	0.747	0.252	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.747	0.252	0.000
N60-N64 Disorders of breast	0.746	0.254	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.745	0.255	0.000
H60-H62 Diseases of external ear	0.745	0.255	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.744	0.256	0.000
H71 Cholesteatoma of middle ear	0.743	0.257	0.000
H52 Disorders of refraction and accommodation	0.742	0.258	0.000
S10-S19 Injuries to the neck	0.742	0.258	0.000
K76.6 Portal hypertension	0.741	0.259	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.741	0.259	0.000
J42 Unspecified chronic bronchitis	0.741	0.259	0.000
C91 Lymphoid leukaemia	0.741	0.259	0.000
I70 Atherosclerosis	0.741	0.259	0.000
A63.0 Anogenital (venereal) warts	0.741	0.259	0.000
K31 Other diseases of stomach and duodenum	0.740	0.260	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.740	0.260	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.739	0.261	0.000
K55-K64 Other diseases of intestines	0.739	0.261	0.000
F31 Bipolar affective disorder	0.738	0.262	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.738	0.262	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.738	0.262	0.000
C85.1 B-cell lymphoma, unspecified	0.737	0.263	0.000
H69 Other disorders of Eustachian tube	0.737	0.263	0.000
K38 Other diseases of appendix	0.736	0.264	0.000
J46 Status asthmaticus	0.735	0.265	0.000
J18.0 Bronchopneumonia, unspecified	0.734	0.265	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.733	0.267	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.733	0.267	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.732	0.268	0.000
K72.9 Hepatic failure, unspecified	0.732	0.268	0.000
I63 Cerebral infarction	0.731	0.268	0.000
J11 Influenza, virus not identified	0.731	0.269	0.000
Y52 Agents primarily affecting the cardiovascular system	0.731	0.269	0.000
C53 Malignant neoplasm of cervix uteri	0.731	0.269	0.000
F17.1 Harmful use	0.730	0.270	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.730	0.270	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.728	0.272	0.000
I47 Paroxysmal tachycardia	0.728	0.272	0.000
K72.0 Acute and subacute hepatic failure	0.727	0.273	0.000
D00-D09 In situ neoplasms	0.726	0.274	0.000
X50-X57 Overexertion, travel and privation	0.725	0.275	0.000
N10 Acute tubulo-interstitial nephritis	0.724	0.276	0.000
Y57 Other and unspecified drugs and medicaments	0.724	0.276	0.000
J43.9 Emphysema, unspecified	0.723	0.277	0.000
S64 Injury of nerves at wrist and hand level	0.722	0.278	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.721	0.279	0.000
N13.8 Other obstructive and reflux uropathy	0.720	0.279	0.000
G70-G73 Diseases of myoneural junction and muscle	0.720	0.280	0.000
C34.3 Lower lobe, bronchus or lung	0.720	0.280	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.719	0.281	0.000
S82.6 Fracture of lateral malleolus	0.719	0.281	0.000
S20-S29 Injuries to the thorax	0.718	0.282	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.716	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.283	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.716	0.284	0.000
I30 Acute pericarditis	0.716	0.284	0.000
N21 Calculus of lower urinary tract	0.716	0.284	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.716	0.284	0.000
B25-B34 Other viral diseases	0.715	0.285	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.715	0.285	0.000
H65 Nonsuppurative otitis media	0.715	0.285	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.714	0.286	0.000
T66-T78 Other and unspecified effects of external causes	0.714	0.286	0.000
I00-I02 Acute rheumatic fever	0.713	0.287	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.713	0.287	0.000
A46 Erysipelas	0.712	0.287	0.000
N02.9 Unspecified	0.712	0.288	0.000
D70 Agranulocytosis	0.712	0.288	0.000
C34.9 Bronchus or lung, unspecified	0.712	0.288	0.000
I05-I09 Chronic rheumatic heart diseases	0.712	0.288	0.000
K77 Liver disorders in diseases classified elsewhere	0.711	0.289	0.000
K73 Chronic hepatitis, not elsewhere classified	0.711	0.289	0.000
K71 Toxic liver disease	0.711	0.289	0.000
B99-B99 Other infectious diseases	0.711	0.289	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.289	0.000
B50-B64 Protozoal diseases	0.711	0.289	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.711	0.289	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.289	0.000
A80-A89 Viral infections of the central nervous system	0.711	0.289	0.000
A75-A79 Rickettsioses	0.711	0.289	0.000
A70-A74 Other diseases caused by chlamydiae	0.711	0.289	0.000
A65-A69 Other spirochaetal diseases	0.711	0.289	0.000
A20-A28 Certain zoonotic bacterial diseases	0.711	0.289	0.000
A15-A19 Tuberculosis	0.711	0.289	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.709	0.291	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.709	0.291	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.707	0.293	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.707	0.293	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.706	0.293	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.706	0.294	0.000
S67 Crushing injury of wrist and hand	0.704	0.296	0.000
S65 Injury of blood vessels at wrist and hand level	0.704	0.296	0.000
N20.9 Urinary calculus, unspecified	0.704	0.296	0.000
I49 Other cardiac arrhythmias	0.704	0.296	0.000
F17.2 Dependence syndrome	0.703	0.297	0.000
H43 Disorders of vitreous body	0.703	0.297	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.297	0.000
N20.2 Calculus of kidney with calculus of ureter	0.703	0.297	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.703	0.297	0.000
H01 Other inflammation of eyelid	0.703	0.297	0.000
C64-C68 Malignant neoplasms of urinary tract	0.703	0.297	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.701	0.299	0.000
I72 Other aneurysm	0.700	0.300	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.700	0.300	0.000
N18.8 Other chronic renal failure	0.699	0.301	0.000
N18.1 Chronic kidney disease, stage 1	0.699	0.301	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.699	0.301	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.699	0.301	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.699	0.301	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.699	0.301	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.699	0.301	0.000
T36 Poisoning by systemic antibiotics	0.699	0.301	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.698	0.302	0.000
J17 Pneumonia in diseases classified elsewhere	0.698	0.302	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.698	0.302	0.000
J12 Viral pneumonia, not elsewhere classified	0.698	0.302	0.000
J10 Influenza due to identified influenza virus	0.698	0.302	0.000
J14 Pneumonia due to Haemophilus influenzae	0.698	0.302	0.000
J09 Influenza due to certain identified influenza virus	0.698	0.302	0.000
S61.8 Open wound of other parts of wrist and hand	0.698	0.302	0.000
N20.1 Calculus of ureter	0.698	0.302	0.000
S91 Open wound of ankle and foot	0.697	0.303	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.696	0.304	0.000
N15 Other renal tubulo-interstitial diseases	0.696	0.304	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.696	0.304	0.000
N11 Chronic tubulo-interstitial nephritis	0.696	0.304	0.000
H00.1 Chalazion	0.696	0.304	0.000
V80-V89 Other land transport accidents	0.696	0.304	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.695	0.305	0.000
K70.0 Alcoholic fatty liver	0.695	0.305	0.000
B37 Candidiasis	0.695	0.305	0.000
N17.8 Other acute renal failure	0.694	0.306	0.000
N17.2 Acute renal failure with medullary necrosis	0.694	0.306	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.694	0.306	0.000
N17.0 Acute renal failure with tubular necrosis	0.694	0.306	0.000
N71 Inflammatory disease of uterus, except cervix	0.694	0.306	0.000
I60 Subarachnoid haemorrhage	0.693	0.307	0.000
J43.2 Centrilobular emphysema	0.692	0.308	0.000
F99-F99 Unspecified mental disorder	0.692	0.308	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.692	0.308	0.000
F70-F79 Mental retardation	0.692	0.308	0.000
A41.9 Septicaemia, unspecified	0.692	0.308	0.000
I52 Other heart disorders in diseases classified elsewhere	0.692	0.308	0.000
I48 Atrial fibrillation and flutter	0.692	0.308	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.692	0.308	0.000
I41 Myocarditis in diseases classified elsewhere	0.692	0.308	0.000
I40 Acute myocarditis	0.692	0.308	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.692	0.308	0.000
I37 Pulmonary valve disorders	0.692	0.308	0.000
I36 Nonrheumatic tricuspid valve disorders	0.692	0.308	0.000
I32 Pericarditis in diseases classified elsewhere	0.692	0.308	0.000
N03.9 Unspecified	0.691	0.309	0.000
I50.1 Left ventricular failure	0.691	0.309	0.000
C32 Malignant neoplasm of larynx	0.690	0.309	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.690	0.310	0.000
H80-H83 Diseases of inner ear	0.689	0.310	0.000
H55-H59 Other disorders of eye and adnexa	0.689	0.310	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.689	0.311	0.000
C34.0 Main bronchus	0.688	0.312	0.000
N18.0 End-stage renal disease	0.688	0.312	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.688	0.312	0.000
H11.0 Pterygium	0.688	0.312	0.000
S69 Other and unspecified injuries of wrist and hand	0.688	0.312	0.000
A49 Bacterial infection of unspecified site	0.687	0.313	0.000
D50-D53 Nutritional anaemias	0.687	0.313	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.687	0.313	0.000
N70 Salpingitis and oophoritis	0.686	0.314	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.686	0.314	0.000
B02 Zoster [herpes zoster]	0.686	0.314	0.000
G30-G32 Other degenerative diseases of the nervous system	0.685	0.315	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.685	0.315	0.000
C95 Leukaemia of unspecified cell type	0.685	0.315	0.000
C94 Other leukaemias of specified cell type	0.685	0.315	0.000
C93 Monocytic leukaemia	0.685	0.315	0.000
C88 Malignant immunoproliferative diseases	0.685	0.315	0.000
C86 Other specified types of T/NK-cell lymphoma	0.685	0.315	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.685	0.315	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.684	0.315	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.684	0.316	0.000
Y40 Systemic antibiotics	0.684	0.316	0.000
F60-F69 Disorders of adult personality and behaviour	0.683	0.317	0.000
N18.5 Chronic kidney disease, stage 5	0.682	0.318	0.000
X60-X84 Intentional self-harm	0.682	0.318	0.000
K45 Other abdominal hernia	0.682	0.318	0.000
S42 Fracture of shoulder and upper arm	0.681	0.319	0.000
S82.60 Fracture of lateral malleolus (closed)	0.679	0.321	0.000
C60-C63 Malignant neoplasms of male genital organs	0.679	0.321	0.000
J18.8 Other pneumonia, organism unspecified	0.679	0.321	0.000
J18.2 Hypostatic pneumonia, unspecified	0.679	0.321	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.679	0.321	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.678	0.321	0.000
H11.9 Disorder of conjunctiva, unspecified	0.678	0.322	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.677	0.323	0.000
K36 Other appendicitis	0.677	0.323	0.000
K25 Gastric ulcer	0.676	0.324	0.000
K22 Other diseases of oesophagus	0.676	0.324	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.675	0.325	0.000
T39.0 Salicylates	0.675	0.325	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.675	0.325	0.000
J80 Adult respiratory distress syndrome	0.674	0.326	0.000
K21 Gastro-oesophageal reflux disease	0.674	0.326	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.674	0.326	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.674	0.326	0.000
Y35-Y36 Legal intervention and operations of war	0.674	0.326	0.000
Y10-Y34 Event of undetermined intent	0.674	0.326	0.000
Y00-Y09 Assault	0.674	0.326	0.000
X85-X99 Assault	0.674	0.326	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.674	0.326	0.000
X30-X39 Exposure to forces of nature	0.674	0.326	0.000
X20-X29 Contact with venomous animals and plants	0.674	0.326	0.000
X10-X19 Contact with heat and hot substances	0.674	0.326	0.000
X00-X09 Exposure to smoke, fire and flames	0.674	0.326	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.674	0.326	0.000
W75-W84 Other accidental threats to breathing	0.674	0.326	0.000
W65-W74 Accidental drowning and submersion	0.674	0.326	0.000
W50-W64 Exposure to animate mechanical forces	0.674	0.326	0.000
V98-V99 Other and unspecified transport accidents	0.674	0.326	0.000
V95-V97 Air and space transport accidents	0.674	0.326	0.000
V90-V94 Water transport accidents	0.674	0.326	0.000
V70-V79 Bus occupant injured in transport accident	0.674	0.326	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.674	0.326	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.674	0.326	0.000
V40-V49 Car occupant injured in transport accident	0.674	0.326	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.674	0.326	0.000
V01-V09 Pedestrian injured in transport accident	0.674	0.326	0.000
I78 Diseases of capillaries	0.673	0.327	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.673	0.327	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.672	0.328	0.000
N13.6 Pyonephrosis	0.672	0.328	0.000
N13.4 Hydroureter	0.672	0.328	0.000
D46 Myelodysplastic syndromes	0.670	0.329	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.669	0.330	0.000
V10-V19 Pedal cyclist injured in transport accident	0.669	0.331	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.668	0.332	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.668	0.332	0.000
C81.9 Hodgkin's disease, unspecified	0.668	0.332	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.668	0.332	0.000
Y43.3 Other antineoplastic drugs	0.667	0.333	0.000
Y85 Sequelae of transport accidents	0.667	0.333	0.000
J20 Acute bronchitis	0.666	0.334	0.000
Y45.1 Salicylates	0.665	0.335	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.665	0.335	0.000
N06 Isolated proteinuria with specified morphological lesion	0.665	0.335	0.000
N05 Unspecified nephritic syndrome	0.665	0.335	0.000
N04 Nephrotic syndrome	0.665	0.335	0.000
N01 Rapidly progressive nephritic syndrome	0.665	0.335	0.000
N00 Acute nephritic syndrome	0.665	0.335	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.662	0.338	0.000
J41 Simple and mucopurulent chronic bronchitis	0.662	0.338	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.662	0.338	0.000
V20-V29 Motorcycle rider injured in transport accident	0.661	0.339	0.000
N25-N29 Other disorders of kidney and ureter	0.660	0.340	0.000
G93 Other disorders of brain	0.660	0.340	0.000
B18 Chronic viral hepatitis	0.660	0.340	0.000
H21 Other disorders of iris and ciliary body	0.659	0.340	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.659	0.341	0.000
F31.9 Bipolar affective disorder, unspecified	0.658	0.342	0.000
J37 Chronic laryngitis and laryngotracheitis	0.657	0.343	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.656	0.344	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.655	0.345	0.000
H52.0 Hypermetropia	0.655	0.345	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.655	0.345	0.000
D73 Diseases of spleen	0.654	0.346	0.000
N76.0 Acute vaginitis	0.654	0.346	0.000
I77 Other disorders of arteries and arterioles	0.653	0.347	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.653	0.347	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.653	0.347	0.000
K35.8 Acute appendicitis, other and unspecified	0.653	0.347	0.000
C34.2 Middle lobe, bronchus or lung	0.652	0.348	0.000
K08 Other disorders of teeth and supporting structures	0.651	0.349	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.651	0.349	0.000
S61.7 Multiple open wounds of wrist and hand	0.651	0.349	0.000
Y59 Other and unspecified vaccines and biological substances	0.651	0.349	0.000
Y58 Bacterial vaccines	0.651	0.349	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.651	0.349	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.651	0.349	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.651	0.349	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.651	0.349	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.651	0.349	0.000
Y48 Anaesthetics and therapeutic gases	0.651	0.349	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.651	0.349	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.651	0.349	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.651	0.349	0.000
I74.5 Embolism and thrombosis of iliac artery	0.651	0.349	0.000
J32.4 Chronic pansinusitis	0.650	0.350	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.650	0.350	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.650	0.350	0.000
H50 Other strabismus	0.650	0.350	0.000
J21 Acute bronchiolitis	0.649	0.351	0.000
S50-S59 Injuries to the elbow and forearm	0.648	0.351	0.001
H54 Blindness and low vision	0.649	0.351	0.000
N60 Benign mammary dysplasia	0.648	0.352	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.647	0.353	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.647	0.353	0.000
T39.4 Antirheumatics, not elsewhere classified	0.647	0.353	0.000
T39.2 Pyrazolone derivatives	0.647	0.353	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.647	0.353	0.000
C51 Malignant neoplasm of vulva	0.647	0.353	0.000
C58 Malignant neoplasm of placenta	0.647	0.353	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.647	0.353	0.000
C52 Malignant neoplasm of vagina	0.647	0.353	0.000
J35 Chronic diseases of tonsils and adenoids	0.647	0.353	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.647	0.353	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.646	0.354	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.646	0.354	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.646	0.354	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.646	0.354	0.000
C85.0 Lymphosarcoma	0.646	0.354	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.645	0.354	0.000
H74 Other disorders of middle ear and mastoid	0.645	0.354	0.000
H70 Mastoiditis and related conditions	0.645	0.354	0.000
H68 Eustachian salpingitis and obstruction	0.645	0.354	0.000
H67 Otitis media in diseases classified elsewhere	0.645	0.354	0.000
J34.2 Deviated nasal septum	0.646	0.354	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.645	0.355	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.645	0.355	0.000
C31 Malignant neoplasm of accessory sinuses	0.645	0.355	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.645	0.355	0.000
C37 Malignant neoplasm of thymus	0.645	0.355	0.000
C33 Malignant neoplasm of trachea	0.645	0.355	0.000
K60 Fissure and fistula of anal and rectal regions	0.645	0.355	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.645	0.355	0.000
K46 Unspecified abdominal hernia	0.644	0.356	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.644	0.356	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations