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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62556547
log Bayes Factor = 41.6654
Chromosome 9   position 22,019,156  (GRCh37) Explore rs62556547 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.001 0.999
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.001 0.999
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
I21 Acute myocardial infarction
0.000 0.003 0.997
C15 Malignant neoplasm of oesophagus
0.996 0.004 0.000
C16 Malignant neoplasm of stomach
0.996 0.004 0.000
I24 Other acute ischaemic heart diseases
0.000 0.007 0.993
C16.0 Cardia
0.981 0.019 0.000
C15.9 Oesophagus, unspecified
0.980 0.020 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.020 0.980
I73 Other peripheral vascular diseases
0.000 0.020 0.980
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.021 0.979
Chapter IX Diseases of the circulatory system
0.000 0.023 0.977
I22 Subsequent myocardial infarction
0.000 0.025 0.975
C19 Malignant neoplasm of rectosigmoid junction
0.971 0.029 0.000
C15.5 Lower third of oesophagus
0.964 0.036 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.043 0.957
I24.8 Other forms of acute ischaemic heart disease
0.000 0.043 0.957
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.067 0.933
I21.4 Acute subendocardial myocardial infarction
0.000 0.071 0.929
C20 Malignant neoplasm of rectum
0.928 0.072 0.000
C16.9 Stomach, unspecified
0.921 0.079 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.921 0.079 0.000
I74 Arterial embolism and thrombosis
0.000 0.086 0.914
C17 Malignant neoplasm of small intestine
0.912 0.088 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.089 0.911
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.098 0.902
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.107 0.893
I20.1 Angina pectoris with documented spasm
0.000 0.116 0.884
C23 Malignant neoplasm of gallbladder
0.875 0.125 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.126 0.874
I60-I69 Cerebrovascular diseases
0.000 0.139 0.861
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.139 0.861
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.144 0.856
I65.2 Occlusion and stenosis of carotid artery
0.000 0.145 0.855
C22.1 Intrahepatic bile duct carcinoma
0.852 0.148 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.161 0.839
C17.0 Duodenum
0.836 0.164 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.177 0.823
I25.3 Aneurysm of heart
0.000 0.180 0.820
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.192 0.808
C16.5 Lesser curvature of stomach, unspecified
0.804 0.196 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.200 0.800
C18 Malignant neoplasm of colon
0.796 0.204 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.217 0.783
I99 Other and unspecified disorders of circulatory system
0.000 0.226 0.774
C16.6 Greater curvature of stomach, unspecified
0.774 0.226 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.231 0.769
I72 Other aneurysm
0.000 0.236 0.764
Z95.3 Presence of xenogenic heart valve
0.000 0.237 0.763
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.239 0.761
C15.4 Middle third of oesophagus
0.759 0.241 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.241 0.759
I73.0 Raynaud's syndrome
0.000 0.243 0.757
I22.8 Subsequent myocardial infarction of other sites
0.000 0.251 0.749
I73.8 Other specified peripheral vascular diseases
0.000 0.251 0.749
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.262 0.738
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.727 0.273 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.277 0.723
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.0 Pure hypercholesterolaemia
0.000 0.283 0.717
I78 Diseases of capillaries
0.000 0.285 0.715
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.285 0.715
C15.8 Overlapping lesion of oesophagus
0.714 0.286 0.000
C15.2 Abdominal part of oesophagus
0.714 0.286 0.000
C15.1 Thoracic part of oesophagus
0.714 0.286 0.000
C15.0 Cervical part of oesophagus
0.714 0.286 0.000
C16.8 Overlapping lesion of stomach
0.714 0.286 0.000
C16.4 Pylorus
0.714 0.286 0.000
C16.3 Pyloric antrum
0.714 0.286 0.000
C16.1 Fundus of stomach
0.714 0.286 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.289 0.710
C16.2 Body of stomach
0.706 0.294 0.000
I70 Atherosclerosis
0.000 0.295 0.705
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.297 0.702
C22.9 Liver, unspecified
0.701 0.299 0.000
C18.2 Ascending colon
0.699 0.301 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.301 0.699
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.301 0.698
I25.4 Coronary artery aneurysm
0.000 0.303 0.696
C17.9 Small intestine, unspecified
0.696 0.304 0.000
C18.7 Sigmoid colon
0.690 0.310 0.000
I24.1 Dressler's syndrome
0.000 0.316 0.684
I23 Certain current complications following acute myocardial infarction
0.000 0.322 0.678
C18.0 Caecum
0.674 0.326 0.000
C25 Malignant neoplasm of pancreas
0.673 0.327 0.000
C22.0 Liver cell carcinoma
0.669 0.331 0.000
I20.8 Other forms of angina pectoris
0.000 0.333 0.667
C17.2 Ileum
0.662 0.338 0.000
C22.7 Other specified carcinomas of liver
0.660 0.340 0.000
C22.4 Other sarcomas of liver
0.660 0.340 0.000
C22.3 Angiosarcoma of liver
0.660 0.340 0.000
C22.2 Hepatoblastoma
0.660 0.340 0.000
C15.3 Upper third of oesophagus
0.658 0.342 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.344 0.655
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.344 0.655
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.344 0.655
C17.8 Overlapping lesion of small intestine
0.654 0.346 0.000
C17.3 Meckel's diverticulum
0.654 0.346 0.000
C17.1 Jejunum
0.654 0.346 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.346 0.654
I72.4 Aneurysm of artery of lower extremity
0.000 0.351 0.649
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.357 0.643
I05-I09 Chronic rheumatic heart diseases
0.000 0.358 0.642
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.358 0.641
I00-I02 Acute rheumatic fever
0.000 0.360 0.640
I69.3 Sequelae of cerebral infarction
0.000 0.382 0.618
C18.3 Hepatic flexure
0.616 0.384 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.386 0.614
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.386 0.614
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.386 0.614
I65.1 Occlusion and stenosis of basilar artery
0.000 0.386 0.614
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.393 0.607
I62 Other nontraumatic intracranial haemorrhage
0.000 0.393 0.607
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.395 0.605
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.396 0.604
I67 Other cerebrovascular diseases
0.000 0.397 0.603
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.400 0.600
C18.8 Overlapping lesion of colon
0.595 0.404 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.412 0.588
I72.8 Aneurysm of other specified arteries
0.000 0.422 0.578
I74.5 Embolism and thrombosis of iliac artery
0.000 0.422 0.578
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.424 0.576
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.430 0.570
C24.1 Ampulla of Vater
0.570 0.430 0.000
I72.2 Aneurysm of renal artery
0.000 0.433 0.567
C18.1 Appendix
0.564 0.436 0.000
Z95.0 Presence of cardiac pacemaker
0.000 0.438 0.562
Z95.4 Presence of other heart-valve replacement
0.000 0.440 0.560
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.445 0.555
I67.1 Cerebral aneurysm, nonruptured
0.000 0.451 0.549
C24.9 Biliary tract, unspecified
0.549 0.451 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.452 0.548
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.452 0.548
I72.1 Aneurysm of artery of upper extremity
0.000 0.452 0.548
I08 Multiple valve diseases
0.000 0.454 0.546
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.454 0.545
I79.1 Aortitis in diseases classified elsewhere
0.000 0.454 0.545
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.454 0.545
I10-I15 Hypertensive diseases
0.000 0.456 0.544
I78.8 Other diseases of capillaries
0.000 0.458 0.542
I72.0 Aneurysm of carotid artery
0.000 0.460 0.540
I74.8 Embolism and thrombosis of other arteries
0.000 0.461 0.539
I71 Aortic aneurysm and dissection
0.000 0.463 0.537
C26 Malignant neoplasm of other and ill-defined digestive organs
0.528 0.471 0.001
C25.1 Body of pancreas
0.528 0.472 0.000
C24.8 Overlapping lesion of biliary tract
0.521 0.478 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.482 0.518
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.482 0.518
I98.0 Cardiovascular syphilis
0.000 0.482 0.518
I78.9 Disease of capillaries, unspecified
0.000 0.487 0.513
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.488 0.512
I70.9 Generalised and unspecified atherosclerosis
0.000 0.494 0.506
I70.8 Atherosclerosis of other arteries
0.000 0.494 0.506
I70.1 Atherosclerosis of renal artery
0.000 0.494 0.506
C25.0 Head of pancreas
0.503 0.497 0.000
I11 Hypertensive heart disease
0.000 0.507 0.493
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.508 0.492
I72.9 Aneurysm of unspecified site
0.000 0.508 0.492
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.514 0.486
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.514 0.486
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.514 0.486
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.514 0.486
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.514 0.486
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.514 0.486
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.514 0.486
C25.8 Overlapping lesion of pancreas
0.482 0.517 0.000
C25.7 Other parts of pancreas
0.482 0.517 0.000
C25.4 Endocrine pancreas
0.482 0.517 0.000
C25.3 Pancreatic duct
0.482 0.517 0.000
C25.2 Tail of pancreas
0.482 0.517 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.518 0.482
I61 Intracerebral haemorrhage
0.000 0.520 0.480
I72.3 Aneurysm of iliac artery
0.000 0.521 0.478
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.527 0.473
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.530 0.470
I97.1 Other functional disturbances following cardiac surgery
0.000 0.530 0.470
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.530 0.469
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.535 0.465
C18.6 Descending colon
0.464 0.536 0.000
I06 Rheumatic aortic valve diseases
0.000 0.539 0.461
I95 Hypotension
0.000 0.540 0.460
I02 Rheumatic chorea
0.000 0.541 0.459
I01 Rheumatic fever with heart involvement
0.000 0.541 0.459
I60 Subarachnoid haemorrhage
0.000 0.542 0.458
C21 Malignant neoplasm of anus and anal canal
0.455 0.545 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.548 0.452
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.551 0.449
I23.8 Other current complications following acute myocardial infarction
0.000 0.553 0.447
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.553 0.447
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.560 0.440
I09 Other rheumatic heart diseases
0.000 0.564 0.436
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.564 0.436
I97.0 Postcardiotomy syndrome
0.000 0.564 0.436
I62.1 Nontraumatic extradural haemorrhage
0.000 0.565 0.435
C18.5 Splenic flexure
0.435 0.565 0.000
C24.0 Extrahepatic bile duct
0.434 0.566 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.568 0.432
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.568 0.432
I67.5 Moyamoya disease
0.000 0.568 0.432
I67.4 Hypertensive encephalopathy
0.000 0.568 0.432
I67.3 Progressive vascular leukoencephalopathy
0.000 0.568 0.432
I67.9 Cerebrovascular disease, unspecified
0.000 0.571 0.429
I71.0 Dissection of aorta [any part]
0.000 0.572 0.428
I08.8 Other multiple valve diseases
0.000 0.578 0.422
I70.0 Atherosclerosis of aorta
0.000 0.584 0.415
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.587 0.413
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.587 0.413
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.587 0.413
I07 Rheumatic tricuspid valve diseases
0.000 0.588 0.412
I95.1 Orthostatic hypotension
0.000 0.590 0.410
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.591 0.409
I77 Other disorders of arteries and arterioles
0.000 0.595 0.405
I00 Rheumatic fever without mention of heart involvement
0.000 0.601 0.398
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.603 0.397
I08.9 Multiple valve disease, unspecified
0.000 0.608 0.391
I13 Hypertensive heart and renal disease
0.000 0.610 0.390
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.615 0.385
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.615 0.385
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.615 0.385
C18.9 Colon, unspecified
0.384 0.616 0.000
C26.8 Overlapping lesion of digestive system
0.379 0.621 0.001
C26.1 Spleen
0.379 0.621 0.001
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.621 0.379
C18.4 Transverse colon
0.377 0.623 0.000
C26.9 Ill-defined sites within the digestive system
0.373 0.627 0.000
I68.0 Cerebral amyloid angiopathy
0.000 0.628 0.372
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.630 0.370
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.630 0.370
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.635 0.364
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.636 0.364
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.637 0.363
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.637 0.363
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.637 0.363
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.637 0.363
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.637 0.363
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.637 0.363
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.639 0.361
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.641 0.359
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.644 0.356
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.644 0.356
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.647 0.353
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.647 0.353
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.647 0.353
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.647 0.353
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.647 0.353
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.648 0.352
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.648 0.352
I15 Secondary hypertension
0.000 0.653 0.347
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.654 0.346
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.655 0.344
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.658 0.342
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.659 0.340
I95.8 Other hypotension
0.000 0.661 0.339
I12 Hypertensive renal disease
0.000 0.663 0.337
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.670 0.330
I06.8 Other rheumatic aortic valve diseases
0.000 0.670 0.330
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.670 0.330
I06.1 Rheumatic aortic insufficiency
0.000 0.670 0.330
I06.0 Rheumatic aortic stenosis
0.000 0.670 0.330
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.671 0.329
I01.8 Other acute rheumatic heart disease
0.000 0.671 0.329
I01.2 Acute rheumatic myocarditis
0.000 0.671 0.329
I01.1 Acute rheumatic endocarditis
0.000 0.671 0.329
I01.0 Acute rheumatic pericarditis
0.000 0.671 0.329
I02.9 Rheumatic chorea without heart involvement
0.000 0.671 0.329
I02.0 Rheumatic chorea with heart involvement
0.000 0.671 0.329
C25.9 Pancreas, unspecified
0.329 0.671 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.671 0.328
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.671 0.328
I61.8 Other intracerebral haemorrhage
0.000 0.672 0.328
C21.2 Cloacogenic zone
0.326 0.673 0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.673 0.326
I05 Rheumatic mitral valve diseases
0.000 0.674 0.326
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.674 0.326
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.674 0.326
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.681 0.318
I95.0 Idiopathic hypotension
0.000 0.682 0.318
I09.8 Other specified rheumatic heart diseases
0.000 0.687 0.313
I09.2 Chronic rheumatic pericarditis
0.000 0.687 0.313
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.687 0.313
I09.0 Rheumatic myocarditis
0.000 0.687 0.313
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.687 0.313
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.690 0.310
C21.8 Overlapping lesion of rectum, anus and anal canal
0.308 0.692 0.001
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.697 0.303
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.702 0.298
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.001 0.702 0.297
I07.9 Tricuspid valve disease, unspecified
0.000 0.704 0.296
I07.8 Other tricuspid valve diseases
0.000 0.704 0.296
I07.2 Tricuspid stenosis with insufficiency
0.000 0.704 0.296
I07.0 Tricuspid stenosis
0.000 0.704 0.296
I67.2 Cerebral atherosclerosis
0.000 0.705 0.295
I77.5 Necrosis of artery
0.000 0.709 0.291
I77.4 Coeliac artery compression syndrome
0.000 0.709 0.291
I77.3 Arterial fibromuscular dysplasia
0.000 0.709 0.291
I09.9 Rheumatic heart disease, unspecified
0.000 0.711 0.289
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.711 0.289
E78.4 Other hyperlipidaemia
0.000 0.717 0.283
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.720 0.280
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.720 0.280
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.720 0.280
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.720 0.280
E10 Insulin-dependent diabetes mellitus
0.000 0.726 0.274
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.728 0.272
I08.0 Disorders of both mitral and aortic valves
0.000 0.729 0.271
E11 Non-insulin-dependent diabetes mellitus
0.000 0.729 0.271
E10-E14 Diabetes mellitus
0.000 0.730 0.270
I12.9 Hypertensive renal disease without renal failure
0.000 0.734 0.266
I77.0 Arteriovenous fistula, acquired
0.000 0.735 0.265
E10.3 With ophthalmic complications
0.000 0.736 0.264
E11.5 With peripheral circulatory complications
0.000 0.737 0.263
C21.0 Anus, unspecified
0.263 0.737 0.001
I77.2 Rupture of artery
0.000 0.738 0.262
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.738 0.261
I77.6 Arteritis, unspecified
0.000 0.738 0.262
E10.4 With neurological complications
0.000 0.743 0.257
I28 Other diseases of pulmonary vessels
0.000 0.744 0.255
E11.9 Without complications
0.000 0.746 0.254
I30-I52 Other forms of heart disease
0.000 0.750 0.250
I15.8 Other secondary hypertension
0.000 0.751 0.249
I15.2 Hypertension secondary to endocrine disorders
0.000 0.751 0.249
I15.0 Renovascular hypertension
0.000 0.751 0.249
I07.1 Tricuspid insufficiency
0.000 0.752 0.247
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.753 0.247
I35 Nonrheumatic aortic valve disorders
0.000 0.756 0.244
E10.5 With peripheral circulatory complications
0.000 0.756 0.244
E14 Unspecified diabetes mellitus
0.000 0.758 0.242
E11.1 With ketoacidosis
0.000 0.760 0.240
I77.8 Other specified disorders of arteries and arterioles
0.000 0.760 0.240
I51 Complications and ill-defined descriptions of heart disease
0.000 0.762 0.238
I95.2 Hypotension due to drugs
0.000 0.766 0.234
I05.8 Other mitral valve diseases
0.000 0.766 0.234
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.767 0.233
E14.3 With ophthalmic complications
0.000 0.767 0.233
I15.9 Seconday hypertension, unspecified
0.000 0.769 0.231
I35.0 Aortic (valve) stenosis
0.000 0.770 0.230
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.770 0.230
I51.7 Cardiomegaly
0.000 0.773 0.227
I15.1 Hypertension secondary to other renal disorders
0.000 0.773 0.227
C21.1 Anal canal
0.226 0.773 0.001
I33 Acute and subacute endocarditis
0.000 0.773 0.227
I05.9 Mitral valve disease, unspecified
0.000 0.773 0.226
I77.1 Stricture of artery
0.000 0.774 0.226
E10.9 Without complications
0.000 0.774 0.226
E78.3 Hyperchylomicronaemia
0.000 0.776 0.224
I05.1 Rheumatic mitral insufficiency
0.000 0.777 0.222
E78.1 Pure hyperglyceridaemia
0.000 0.786 0.214
I60.8 Other subarachnoid haemorrhage
0.001 0.787 0.212
E78.8 Other disorders of lipoprotein metabolism
0.000 0.788 0.212
E78.6 Lipoprotein deficiency
0.000 0.789 0.211
I05.2 Mitral stenosis with insufficiency
0.000 0.789 0.210
I33.0 Acute and subacute infective endocarditis
0.000 0.789 0.211
I51.6 Cardiovascular disease, unspecified
0.000 0.791 0.209
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.792 0.207
E11.6 With other specified complications
0.000 0.793 0.207
E11.8 With unspecified complications
0.000 0.794 0.206
E11.2 With renal complications
0.000 0.794 0.206
C26.0 Intestinal tract, part unspecified
0.204 0.795 0.001
E10.6 With other specified complications
0.000 0.801 0.199
E10.7 With multiple complications
0.000 0.803 0.197
I35.8 Other aortic valve disorders
0.000 0.803 0.197
E10.0 With coma
0.000 0.804 0.196
E78.2 Mixed hyperlipidaemia
0.000 0.805 0.195
E10.8 With unspecified complications
0.000 0.805 0.194
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.806 0.194
E11.7 With multiple complications
0.000 0.806 0.194
E12 Malnutrition-related diabetes mellitus
0.000 0.807 0.193
I37 Pulmonary valve disorders
0.000 0.807 0.193
I67.8 Other specified cerebrovascular diseases
0.000 0.809 0.191
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.812 0.188
Z95.2 Presence of prosthetic heart valve
0.000 0.813 0.186
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.814 0.186
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.816 0.183
I28.8 Other specified diseases of pulmonary vessels
0.000 0.816 0.183
I28.1 Aneurysm of pulmonary artery
0.000 0.816 0.183
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.816 0.183
I51.4 Myocarditis, unspecified
0.000 0.819 0.181
I50 Heart failure
0.000 0.820 0.180
E11.0 With coma
0.000 0.820 0.180
I52 Other heart disorders in diseases classified elsewhere
0.000 0.821 0.179
I48 Atrial fibrillation and flutter
0.000 0.821 0.179
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.821 0.179
I41 Myocarditis in diseases classified elsewhere
0.000 0.821 0.179
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.821 0.179
I32 Pericarditis in diseases classified elsewhere
0.000 0.821 0.179
I36 Nonrheumatic tricuspid valve disorders
0.000 0.821 0.179
I05.0 Mitral stenosis
0.000 0.821 0.178
E14.7 With multiple complications
0.000 0.826 0.174
E14.6 With other specified complications
0.000 0.826 0.174
E14.5 With peripheral circulatory complications
0.000 0.826 0.174
E14.4 With neurological complications
0.000 0.826 0.174
E14.2 Withrenal complications
0.000 0.826 0.174
E14.1 With ketoacidosis
0.000 0.826 0.174
E14.0 With coma
0.000 0.826 0.174
I51.5 Myocardial degeneration
0.000 0.829 0.171
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.829 0.171
E10.1 With ketoacidosis
0.000 0.830 0.170
E14.8 With unspecified complications
0.000 0.831 0.169
E10.2 With renal complications
0.000 0.831 0.169
E13 Other specified diabetes mellitus
0.000 0.834 0.166
I30 Acute pericarditis
0.000 0.836 0.164
I33.9 Acute endocarditis, unspecified
0.000 0.837 0.163
I40 Acute myocarditis
0.000 0.838 0.161
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.843 0.157
I50.9 Heart failure, unspecified
0.000 0.843 0.157
I26 Pulmonary embolism
0.001 0.845 0.155
E11.4 With neurological complications
0.000 0.845 0.155
I51.0 Cardiac septal defect, acquired
0.000 0.846 0.154
I37.1 Pulmonary valve insufficiency
0.000 0.847 0.153
I63 Cerebral infarction
0.000 0.847 0.153
I51.8 Other ill-defined heart diseases
0.000 0.852 0.148
I50.1 Left ventricular failure
0.000 0.854 0.146
I38 Endocarditis, valve unspecified
0.000 0.859 0.141
I51.9 Heart disease, unspecified
0.000 0.859 0.141
E12.9 Without complications
0.000 0.861 0.139
E12.8 With unspecified complications
0.000 0.861 0.139
E12.7 With multiple complications
0.000 0.861 0.139
E12.6 With other specified complications
0.000 0.861 0.139
E12.5 With peripheral circulatory complications
0.000 0.861 0.139
E12.4 With neurological complications
0.000 0.861 0.139
E12.3 With ophthalmic complications
0.000 0.861 0.139
E12.2 With renal complications
0.000 0.861 0.139
E12.1 With ketoacidosis
0.000 0.861 0.139
E12.0 With coma
0.000 0.861 0.139
I37.9 Pulmonary valve disorder, unspecified
0.000 0.861 0.139
I37.8 Other pulmonary valve disorders
0.000 0.861 0.139
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.861 0.139
I37.0 Pulmonary valve stenosis
0.000 0.861 0.139
I12.0 Hypertensive renal disease with renal failure
0.000 0.862 0.138
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.862 0.138
I27 Other pulmonary heart diseases
0.000 0.867 0.133
I46 Cardiac arrest
0.000 0.867 0.133
I35.9 Aortic valve disorder, unspecified
0.000 0.867 0.133
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.871 0.128
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.871 0.128
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.871 0.128
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.871 0.128
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.871 0.128
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.871 0.128
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.871 0.128
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.871 0.128
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.871 0.128
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.871 0.128
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.871 0.128
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.871 0.128
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.871 0.128
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.871 0.128
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.871 0.128
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.871 0.128
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.871 0.128
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.871 0.128
I48.4 Atypical atrial flutter
0.000 0.871 0.128
I48.3 Typical atrial flutter
0.000 0.871 0.128
I48.2 Chronic atrial fibrillation
0.000 0.871 0.128
I48.1 Persistent atrial fibrillation
0.000 0.871 0.128
I48.0 Paroxysmal atrial fibrillation
0.000 0.871 0.128
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.871 0.128
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.871 0.128
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.871 0.128
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.872 0.128
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.872 0.128
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.872 0.128
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.872 0.128
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.872 0.128
I30.9 Acute pericarditis, unspecified
0.000 0.876 0.124
I31 Other diseases of pericardium
0.000 0.877 0.123
I34 Nonrheumatic mitral valve disorders
0.000 0.880 0.120
E14.9 Without complications
0.000 0.880 0.120
E13.8 With unspecified complications
0.000 0.881 0.119
E13.7 With multiple complications
0.000 0.881 0.119
E13.6 With other specified complications
0.000 0.881 0.119
E13.5 With peripheral circulatory complications
0.000 0.881 0.119
E13.4 With neurological complications
0.000 0.881 0.119
E13.3 With ophthalmic complications
0.000 0.881 0.119
E13.2 With renal complications
0.000 0.881 0.119
E13.1 With ketoacidosis
0.000 0.881 0.119
E13.0 With coma
0.000 0.881 0.119
I30.8 Other forms of acute pericarditis
0.000 0.882 0.118
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.882 0.118
I40.9 Acute myocarditis, unspecified
0.000 0.884 0.116
I40.8 Other acute myocarditis
0.000 0.884 0.116
I40.1 Isolated myocarditis
0.000 0.884 0.116
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.886 0.113
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.890 0.110
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.890 0.110
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.890 0.110
I35.1 Aortic (valve) insufficiency
0.000 0.892 0.108
I78.1 Naevus, nonneoplastic
0.001 0.894 0.105
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.897 0.103

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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