TreeWAS – Variant ID: rs635634

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	1.000	0.000	0.000
I84 Haemorrhoids	0.000	0.000	1.000
I80 Phlebitis and thrombophlebitis	1.000	0.000	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I50 Heart failure	1.000	0.000	0.000
I26 Pulmonary embolism	1.000	0.000	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	1.000	0.000	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.001	0.999
I30-I52 Other forms of heart disease	0.999	0.001	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.999	0.001	0.000
I50.1 Left ventricular failure	0.999	0.001	0.000
I83 Varicose veins of lower extremities	0.999	0.001	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.002	0.998
I84.9 Unspecified haemorrhoids without complication	0.000	0.002	0.998
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.004	0.996
I63 Cerebral infarction	0.994	0.006	0.000
I60-I69 Cerebrovascular diseases	0.993	0.007	0.000
I63.9 Cerebral infarction, unspecified	0.992	0.008	0.000
I25.2 Old myocardial infarction	0.985	0.015	0.000
I05-I09 Chronic rheumatic heart diseases	0.984	0.016	0.000
M79.66 Pain in limb (Lower leg)	0.984	0.016	0.000
M79.8 Other specified soft tissue disorders	0.983	0.017	0.000
I50.0 Congestive heart failure	0.982	0.018	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.982	0.018	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.981	0.019	0.000
M79.6 Pain in limb	0.981	0.019	0.000
I50.9 Heart failure, unspecified	0.981	0.019	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.981	0.019	0.000
K26 Duodenal ulcer	0.000	0.027	0.973
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.965	0.035	0.000
K26.3 Acute without haemorrhage or perforation	0.000	0.038	0.962
I24 Other acute ischaemic heart diseases	0.961	0.039	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.961	0.039	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.043	0.957
I21 Acute myocardial infarction	0.955	0.045	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.953	0.047	0.000
I08 Multiple valve diseases	0.951	0.049	0.000
K26.5 Chronic or unspecified with perforation	0.000	0.049	0.951
I84.2 Internal haemorrhoids without complication	0.000	0.051	0.949
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.945	0.055	0.000
K83 Other diseases of biliary tract	0.944	0.056	0.000
I46 Cardiac arrest	0.943	0.057	0.000
I25.5 Ischaemic cardiomyopathy	0.940	0.060	0.000
I51 Complications and ill-defined descriptions of heart disease	0.939	0.061	0.000
K82 Other diseases of gallbladder	0.939	0.061	0.000
K80 Cholelithiasis	0.938	0.062	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.935	0.065	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.066	0.934
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.931	0.069	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.929	0.071	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.927	0.073	0.000
I46.9 Cardiac arrest, unspecified	0.926	0.074	0.000
K83.1 Obstruction of bile duct	0.925	0.075	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.925	0.075	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.076	0.924
K82.8 Other specified diseases of gallbladder	0.922	0.078	0.000
I63.8 Other cerebral infarction	0.916	0.084	0.000
I44 Atrioventricular and left bundle-branch block	0.915	0.085	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.909	0.091	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.906	0.094	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.906	0.094	0.000
I05 Rheumatic mitral valve diseases	0.903	0.097	0.000
I81 Portal vein thrombosis	0.902	0.098	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.898	0.102	0.000
I82 Other venous embolism and thrombosis	0.895	0.105	0.000
I08.0 Disorders of both mitral and aortic valves	0.888	0.112	0.000
I84.4 External haemorrhoids with other complications	0.000	0.113	0.887
M79.1 Myalgia	0.887	0.113	0.000
M79.61 Pain in limb (Shoulder region)	0.885	0.115	0.000
I89.0 Lymphoedema, not elsewhere classified	0.885	0.115	0.000
K83.0 Cholangitis	0.878	0.122	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.870	0.129	0.000
K83.8 Other specified diseases of biliary tract	0.870	0.130	0.000
K82.4 Cholesterolosis of gallbladder	0.869	0.131	0.000
K86 Other diseases of pancreas	0.864	0.136	0.000
I51.8 Other ill-defined heart diseases	0.863	0.137	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.137	0.863
M79.82 Other specified soft tissue disorders (Upper arm)	0.862	0.138	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.143	0.857
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.855	0.145	0.000
I85 Oesophageal varices	0.855	0.145	0.000
M79.63 Pain in limb (Forearm)	0.854	0.146	0.000
I44.3 Other and unspecified atrioventricular block	0.850	0.150	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.846	0.154	0.000
K86.2 Cyst of pancreas	0.845	0.155	0.000
I21.9 Acute myocardial infarction, unspecified	0.844	0.156	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.840	0.160	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.840	0.160	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.840	0.160	0.000
I23 Certain current complications following acute myocardial infarction	0.834	0.166	0.000
I31 Other diseases of pericardium	0.827	0.173	0.000
I25.3 Aneurysm of heart	0.823	0.177	0.000
K26.0 Acute with haemorrhage	0.000	0.178	0.822
I09 Other rheumatic heart diseases	0.821	0.179	0.000
M79.9 Soft tissue disorder, unspecified	0.817	0.183	0.000
K80.8 Other cholelithiasis	0.803	0.197	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.802	0.198	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.799	0.200	0.000
I24.8 Other forms of acute ischaemic heart disease	0.798	0.202	0.000
I82.0 Budd-Chiari syndrome	0.794	0.206	0.000
M79.64 Pain in limb (Hand)	0.792	0.208	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.787	0.213	0.000
I05.9 Mitral valve disease, unspecified	0.786	0.214	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.782	0.218	0.000
I44.2 Atrioventricular block, complete	0.778	0.222	0.000
I84.5 External haemorrhoids without complication	0.000	0.224	0.776
I85.9 Oesophageal varices without bleeding	0.772	0.228	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.772	0.228	0.000
I51.4 Myocarditis, unspecified	0.769	0.231	0.000
I44.4 Left anterior fascicular block	0.766	0.234	0.000
I05.1 Rheumatic mitral insufficiency	0.764	0.236	0.000
E78.5 Hyperlipidaemia, unspecified	0.759	0.241	0.000
M79.5 Residual foreign body in soft tissue	0.757	0.243	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.755	0.245	0.000
M79.19 Myalgia (Site unspecified)	0.754	0.246	0.000
I82.8 Embolism and thrombosis of other specified veins	0.750	0.250	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.748	0.252	0.000
I40 Acute myocarditis	0.745	0.254	0.000
K86.9 Disease of pancreas, unspecified	0.746	0.254	0.000
I24.1 Dressler's syndrome	0.745	0.255	0.000
E78.6 Lipoprotein deficiency	0.742	0.258	0.000
I51.7 Cardiomegaly	0.727	0.273	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.723	0.277	0.000
I33 Acute and subacute endocarditis	0.721	0.278	0.000
I25.4 Coronary artery aneurysm	0.720	0.280	0.000
M79.18 Myalgia (Other)	0.719	0.281	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.716	0.283	0.000
I48 Atrial fibrillation and flutter	0.716	0.283	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.283	0.000
I41 Myocarditis in diseases classified elsewhere	0.716	0.283	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.283	0.000
I32 Pericarditis in diseases classified elsewhere	0.716	0.283	0.000
K82.0 Obstruction of gallbladder	0.715	0.284	0.000
I23.8 Other current complications following acute myocardial infarction	0.715	0.285	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.713	0.287	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.713	0.287	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.712	0.288	0.000
I51.0 Cardiac septal defect, acquired	0.711	0.289	0.000
I62 Other nontraumatic intracranial haemorrhage	0.710	0.290	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.708	0.292	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.704	0.295	0.000
I09.9 Rheumatic heart disease, unspecified	0.704	0.296	0.000
M79.3 Panniculitis, unspecified	0.704	0.296	0.000
M79.7 Fibromyalgia	0.702	0.298	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.302	0.698
I31.3 Pericardial effusion (noninflammatory)	0.697	0.303	0.000
I27 Other pulmonary heart diseases	0.696	0.304	0.000
I87 Other disorders of veins	0.694	0.306	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.692	0.308	0.000
I06 Rheumatic aortic valve diseases	0.691	0.309	0.000
K82.9 Disease of gallbladder, unspecified	0.691	0.309	0.000
I08.8 Other multiple valve diseases	0.687	0.313	0.000
I05.2 Mitral stenosis with insufficiency	0.687	0.313	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.686	0.314	0.000
M79.88 Other specified soft tissue disorders (Other)	0.685	0.315	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.685	0.315	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.684	0.316	0.000
M79.16 Myalgia (Lower leg)	0.679	0.321	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.678	0.322	0.000
M79.60 Pain in limb (Multiple sites)	0.677	0.323	0.000
M79.68 Pain in limb (Other)	0.677	0.323	0.000
K83.5 Biliary cyst	0.677	0.323	0.000
K83.4 Spasm of sphincter of Oddi	0.677	0.323	0.000
K83.3 Fistula of bile duct	0.677	0.323	0.000
K83.2 Perforation of bile duct	0.677	0.323	0.000
I46.1 Sudden cardiac death, so described	0.676	0.324	0.000
I51.5 Myocardial degeneration	0.673	0.326	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.673	0.326	0.000
K80.3 Calculus of bile duct with cholangitis	0.672	0.327	0.000
K82.3 Fistula of gallbladder	0.671	0.328	0.000
I44.6 Other and unspecified fascicular block	0.668	0.332	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.663	0.337	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.661	0.339	0.000
I44.5 Left posterior fascicular block	0.656	0.344	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.653	0.347	0.000
I44.0 Atrioventricular block, first degree	0.650	0.350	0.000
I22 Subsequent myocardial infarction	0.648	0.352	0.000
K82.1 Hydrops of gallbladder	0.648	0.352	0.000
I05.8 Other mitral valve diseases	0.647	0.352	0.000
K26.2 Acute with both haemorrhage and perforation	0.000	0.358	0.642
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.358	0.642
I82.1 Thrombophlebitis migrans	0.642	0.358	0.000
I31.1 Chronic constrictive pericarditis	0.639	0.361	0.000
M79.17 Myalgia (Ankle and foot)	0.636	0.364	0.000
M79.14 Myalgia (Hand)	0.636	0.364	0.000
M79.13 Myalgia (Forearm)	0.636	0.364	0.000
M79.12 Myalgia (Upper arm)	0.636	0.364	0.000
M79.11 Myalgia (Shoulder region)	0.636	0.364	0.000
I08.9 Multiple valve disease, unspecified	0.636	0.364	0.000
M79.10 Myalgia (Multiple sites)	0.633	0.367	0.000
K26.1 Acute with perforation	0.000	0.370	0.630
I84.0 Internal thrombosed haemorrhoids	0.000	0.371	0.629
I05.0 Mitral stenosis	0.628	0.372	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.625	0.374	0.000
I51.9 Heart disease, unspecified	0.625	0.375	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.624	0.376	0.000
I30 Acute pericarditis	0.621	0.379	0.000
I31.0 Chronic adhesive pericarditis	0.620	0.380	0.000
I82.3 Embolism and thrombosis of renal vein	0.620	0.380	0.000
M79.2 Neuralgia and neuritis, unspecified	0.620	0.380	0.000
I82.2 Embolism and thrombosis of vena cava	0.618	0.382	0.000
I28 Other diseases of pulmonary vessels	0.617	0.383	0.000
K82.2 Perforation of gallbladder	0.617	0.383	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.617	0.383	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.610	0.390	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.604	0.396	0.000
E78.3 Hyperchylomicronaemia	0.602	0.398	0.000
I88 Nonspecific lymphadenitis	0.602	0.398	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.602	0.398	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.602	0.398	0.000
I65.1 Occlusion and stenosis of basilar artery	0.602	0.398	0.000
I27.2 Other secondary pulmonary hypertension	0.602	0.398	0.000
I69 Sequelae of cerebrovascular disease	0.600	0.400	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.598	0.402	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.598	0.402	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.598	0.402	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.598	0.402	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.598	0.402	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.598	0.402	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.598	0.402	0.000
I45 Other conduction disorders	0.596	0.404	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.595	0.405	0.000
I31.8 Other specified diseases of pericardium	0.593	0.407	0.000
I31.2 Haemopericardium, not elsewhere classified	0.593	0.407	0.000
I37 Pulmonary valve disorders	0.591	0.409	0.000
I09.8 Other specified rheumatic heart diseases	0.589	0.411	0.000
I09.2 Chronic rheumatic pericarditis	0.589	0.411	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.589	0.411	0.000
I09.0 Rheumatic myocarditis	0.589	0.411	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.586	0.414	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.586	0.414	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.586	0.414	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.586	0.414	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.586	0.414	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.586	0.414	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.586	0.414	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.586	0.414	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.585	0.414	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.585	0.415	0.000
M79.70 Fibromyalgia (Multiple sites)	0.584	0.416	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.581	0.419	0.000
I89.1 Lymphangitis	0.581	0.419	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.578	0.422	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.576	0.423	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.572	0.428	0.000
M79.69 Pain in limb (Site unspecified)	0.571	0.429	0.000
I65.2 Occlusion and stenosis of carotid artery	0.570	0.430	0.000
E78.1 Pure hyperglyceridaemia	0.569	0.431	0.000
K57 Diverticular disease of intestine	0.000	0.431	0.569
I08.1 Disorders of both mitral and tricuspid valves	0.567	0.433	0.000
I40.0 Infective myocarditis	0.564	0.436	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.559	0.441	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.554	0.446	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.553	0.446	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.553	0.446	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.553	0.446	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.553	0.446	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.553	0.446	0.000
I85.0 Oesophageal varices with bleeding	0.550	0.450	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.545	0.455	0.000
I44.1 Atrioventricular block, second degree	0.543	0.457	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.542	0.457	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.542	0.457	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.542	0.457	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.542	0.457	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.542	0.457	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.542	0.457	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.542	0.457	0.000
I38 Endocarditis, valve unspecified	0.541	0.459	0.000
K80.4 Calculus of bile duct with cholecystitis	0.541	0.459	0.000
I40.9 Acute myocarditis, unspecified	0.534	0.465	0.000
I40.8 Other acute myocarditis	0.534	0.465	0.000
I40.1 Isolated myocarditis	0.534	0.465	0.000
I33.0 Acute and subacute infective endocarditis	0.534	0.466	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.533	0.467	0.000
I42 Cardiomyopathy	0.531	0.469	0.000
M70-M79 Other soft tissue disorders	0.527	0.473	0.000
K83.9 Disease of biliary tract, unspecified	0.526	0.473	0.000
I45.1 Other and unspecified right bundle-branch block	0.517	0.483	0.000
I31.9 Disease of pericardium, unspecified	0.516	0.484	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.515	0.485	0.000
I02 Rheumatic chorea	0.514	0.486	0.000
I01 Rheumatic fever with heart involvement	0.514	0.486	0.000
I00 Rheumatic fever without mention of heart involvement	0.514	0.486	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.514	0.486	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.514	0.486	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.514	0.486	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.514	0.486	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.514	0.486	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.514	0.486	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.514	0.486	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.514	0.486	0.000
I48.4 Atypical atrial flutter	0.514	0.486	0.000
I48.3 Typical atrial flutter	0.514	0.486	0.000
I48.2 Chronic atrial fibrillation	0.514	0.486	0.000
I48.1 Persistent atrial fibrillation	0.514	0.486	0.000
I48.0 Paroxysmal atrial fibrillation	0.514	0.486	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.514	0.486	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.514	0.486	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.510	0.489	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.510	0.489	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.510	0.489	0.000
I68.0 Cerebral amyloid angiopathy	0.510	0.489	0.000
I62.1 Nontraumatic extradural haemorrhage	0.509	0.491	0.000
M79.39 Panniculitis, unspecified (Site unspecified)	0.505	0.495	0.000
M79.38 Panniculitis, unspecified (Other)	0.505	0.495	0.000
M79.37 Panniculitis, unspecified (Ankle and foot)	0.505	0.495	0.000
M79.36 Panniculitis, unspecified (Lower leg)	0.505	0.495	0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.505	0.495	0.000
M79.34 Panniculitis, unspecified (Hand)	0.505	0.495	0.000
M79.33 Panniculitis, unspecified (Forearm)	0.505	0.495	0.000
M79.32 Panniculitis, unspecified (Upper arm)	0.505	0.495	0.000
M79.31 Panniculitis, unspecified (Shoulder region)	0.505	0.495	0.000
M79.30 Panniculitis, unspecified (Multiple sites)	0.505	0.495	0.000
I36 Nonrheumatic tricuspid valve disorders	0.504	0.495	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.505	0.495	0.000
I33.9 Acute endocarditis, unspecified	0.504	0.496	0.000
M79.78 Fibromyalgia (Other)	0.503	0.497	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.503	0.497	0.000
M79.76 Fibromyalgia (Lower leg)	0.503	0.497	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.503	0.497	0.000
M79.74 Fibromyalgia (Hand)	0.503	0.497	0.000
M79.73 Fibromyalgia (Forearm)	0.503	0.497	0.000
M79.72 Fibromyalgia (Upper arm)	0.503	0.497	0.000
M79.71 Fibromyalgia (Shoulder region)	0.503	0.497	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.501	0.499	0.000
K86.8 Other specified diseases of pancreas	0.500	0.500	0.000
I27.1 Kyphoscoliotic heart disease	0.499	0.501	0.000
I87.9 Disorder of vein, unspecified	0.498	0.502	0.000
I87.0 Postphlebitic syndrome	0.498	0.502	0.000
E78.8 Other disorders of lipoprotein metabolism	0.497	0.503	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.496	0.504	0.000
I06.8 Other rheumatic aortic valve diseases	0.496	0.504	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.496	0.504	0.000
I06.1 Rheumatic aortic insufficiency	0.496	0.504	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.495	0.505	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.491	0.509	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.486	0.514	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.486	0.514	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.485	0.515	0.000
I27.8 Other specified pulmonary heart diseases	0.484	0.516	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.482	0.518	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.482	0.518	0.000
I06.0 Rheumatic aortic stenosis	0.481	0.518	0.000
M71 Other bursopathies	0.478	0.521	0.000
K86.1 Other chronic pancreatitis	0.478	0.522	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.474	0.525	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.474	0.526	0.000
I51.6 Cardiovascular disease, unspecified	0.464	0.536	0.000
I07 Rheumatic tricuspid valve diseases	0.461	0.538	0.001
I21.3 Acute transmural myocardial infarction of unspecified site	0.461	0.538	0.001
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.538	0.462
I45.3 Trifascicular block	0.456	0.544	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.448	0.551	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.448	0.551	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.448	0.551	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.448	0.551	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.448	0.551	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.448	0.551	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.448	0.551	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.448	0.551	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.448	0.551	0.000
I30.1 Infective pericarditis	0.447	0.553	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.447	0.553	0.000
I42.6 Alcoholic cardiomyopathy	0.446	0.554	0.000
I27.9 Pulmonary heart disease, unspecified	0.445	0.555	0.000
I30.8 Other forms of acute pericarditis	0.445	0.555	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.445	0.555	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.445	0.555	0.000
I45.5 Other specified heart block	0.445	0.555	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.444	0.556	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.444	0.556	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.444	0.556	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.444	0.556	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.442	0.557	0.000
I28.1 Aneurysm of pulmonary artery	0.442	0.557	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.442	0.557	0.000
K86.3 Pseudocyst of pancreas	0.437	0.563	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.563	0.437
M71.2 Synovial cyst of popliteal space [Baker]	0.435	0.565	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.434	0.566	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.433	0.566	0.000
I88.8 Other nonspecific lymphadenitis	0.432	0.568	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.432	0.568	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.432	0.568	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.431	0.569	0.000
I45.0 Right fascicular block	0.427	0.573	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.427	0.573	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.574	0.426
I42.7 Cardiomyopathy due to drugs and other external agents	0.425	0.574	0.000
I37.9 Pulmonary valve disorder, unspecified	0.424	0.576	0.000
I37.8 Other pulmonary valve disorders	0.424	0.576	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.424	0.576	0.000
I37.0 Pulmonary valve stenosis	0.424	0.576	0.000
M79.0 Rheumatism, unspecified	0.424	0.576	0.000
I45.2 Bifascicular block	0.423	0.577	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.423	0.577	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.422	0.578	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.578	0.422
E78.4 Other hyperlipidaemia	0.420	0.579	0.000
K92.1 Melaena	0.000	0.583	0.417
I45.4 Nonspecific intraventricular block	0.416	0.584	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.584	0.416
M79.67 Pain in limb (Ankle and foot)	0.413	0.587	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.409	0.591	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.592	0.408
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.404	0.595	0.000
I87.1 Compression of vein	0.404	0.596	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.403	0.597	0.000
I74 Arterial embolism and thrombosis	0.401	0.599	0.000
I86 Varicose veins of other sites	0.400	0.600	0.000
I22.8 Subsequent myocardial infarction of other sites	0.399	0.600	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.391	0.608	0.001
M77 Other enthesopathies	0.391	0.609	0.000
M76 Enthesopathies of lower limb, excluding foot	0.386	0.614	0.000
M71.9 Bursopathy, unspecified	0.384	0.616	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.382	0.617	0.000
I42.5 Other restrictive cardiomyopathy	0.381	0.619	0.000
I42.4 Endocardial fibroelastosis	0.381	0.619	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.381	0.619	0.000
I45.8 Other specified conduction disorders	0.381	0.619	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.378	0.622	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.370	0.630	0.000
K81 Cholecystitis	0.369	0.631	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.369	0.631	0.000
I01.8 Other acute rheumatic heart disease	0.369	0.631	0.000
I01.2 Acute rheumatic myocarditis	0.369	0.631	0.000
I01.1 Acute rheumatic endocarditis	0.369	0.631	0.000
I01.0 Acute rheumatic pericarditis	0.369	0.631	0.000
I02.9 Rheumatic chorea without heart involvement	0.369	0.631	0.000
I02.0 Rheumatic chorea with heart involvement	0.369	0.631	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.366	0.634	0.000
I27.0 Primary pulmonary hypertension	0.365	0.635	0.000
M79.79 Fibromyalgia (Site unspecified)	0.365	0.635	0.000
I70 Atherosclerosis	0.363	0.637	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.361	0.638	0.001
I36.8 Other nonrheumatic tricuspid valve disorders	0.361	0.638	0.001
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.361	0.638	0.001
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.361	0.638	0.001
C25.9 Pancreas, unspecified	0.351	0.649	0.000
K85 Acute pancreatitis	0.350	0.650	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.349	0.651	0.000
I44.7 Left bundle-branch block, unspecified	0.348	0.652	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.348	0.652	0.000
C25 Malignant neoplasm of pancreas	0.347	0.653	0.000
I30.9 Acute pericarditis, unspecified	0.346	0.654	0.000
D68.2 Hereditary deficiency of other clotting factors	0.345	0.655	0.000
I69.3 Sequelae of cerebral infarction	0.345	0.655	0.000
I42.2 Other hypertrophic cardiomyopathy	0.344	0.656	0.000
M71.8 Other specified bursopathies	0.343	0.657	0.000
M71.5 Other bursitis, not elsewhere classified	0.343	0.657	0.000
M71.4 Calcium deposit in bursa	0.343	0.657	0.000
M71.0 Abscess of bursa	0.343	0.657	0.000
I28.8 Other specified diseases of pulmonary vessels	0.343	0.657	0.001
M71.3 Other bursal cyst	0.342	0.658	0.000
C25.0 Head of pancreas	0.341	0.659	0.000
M72 Fibroblastic disorders	0.338	0.662	0.000
D68 Other coagulation defects	0.338	0.662	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.335	0.665	0.000
I42.8 Other cardiomyopathies	0.334	0.665	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.666	0.334
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.333	0.666	0.000
I07.9 Tricuspid valve disease, unspecified	0.331	0.668	0.001
I07.8 Other tricuspid valve diseases	0.331	0.668	0.001
I07.2 Tricuspid stenosis with insufficiency	0.331	0.668	0.001
I07.0 Tricuspid stenosis	0.331	0.668	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.331	0.669	0.000
M77.4 Metatarsalgia	0.331	0.669	0.000
D68.5 Primary Thrombophilia	0.329	0.671	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.328	0.672	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.328	0.672	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.328	0.672	0.000
M71.1 Other infective bursitis	0.325	0.675	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.323	0.676	0.000
M79.62 Pain in limb (Upper arm)	0.321	0.679	0.000
I45.6 Preexcitation syndrome	0.318	0.681	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.316	0.683	0.001
M71.97 Bursopathy, unspecified (Ankle and foot)	0.316	0.684	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.314	0.686	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations