TreeWAS – Variant ID: rs6439371

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y60.0 During surgical operation	0.111	0.889	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.074	0.926	0.000
O48 Prolonged pregnancy	0.000	0.937	0.063
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.937	0.063
Y60.5 During heart catheterisation	0.062	0.938	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.939	0.061
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.939	0.061
Y60.8 During other surgical and medical care	0.059	0.941	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.941	0.059
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.942	0.058
O36.8 Maternal care for other specified foetal problems	0.000	0.943	0.057
O33 Maternal care for known or suspected disproportion	0.000	0.946	0.054
Y60.6 During aspiration, puncture and other catheterisation	0.053	0.946	0.000
Y60.9 During unspecified surgical and medical care	0.053	0.947	0.000
Y60.7 During administration of enema	0.053	0.947	0.000
Y60.3 During injection or immunisation	0.053	0.947	0.000
Y60.2 During kidney dialysis or other perfusion	0.053	0.947	0.000
Y60.1 During infusion or transfusion	0.053	0.947	0.000
O44 Placenta praevia	0.000	0.947	0.053
O34.3 Maternal care for cervical incompetence	0.000	0.947	0.053
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.947	0.053
O34.1 Maternal care for tumour of corpus uteri	0.000	0.948	0.052
O36.9 Maternal care for foetal problem, unspecified	0.000	0.949	0.051
O36.1 Maternal care for other isoimmunisation	0.000	0.950	0.050
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.950	0.050
O41 Other disorders of amniotic fluid and membranes	0.000	0.951	0.049
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.952	0.048
O34.0 Maternal care for congenital malformation of uterus	0.000	0.952	0.048
O33.9 Maternal care for disproportion, unspecified	0.000	0.952	0.048
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.953	0.047
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.953	0.046
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.954	0.046
Y60.4 During endoscopic examination	0.046	0.954	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.954	0.046
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.954	0.046
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.955	0.044
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.956	0.044
O36.2 Maternal care for hydrops foetalis	0.000	0.956	0.044
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.956	0.044
O34.6 Maternal care for abnormality of vagina	0.000	0.956	0.044
O32.2 Maternal care for transverse and oblique lie	0.000	0.956	0.044
O36.6 Maternal care for excessive foetal growth	0.000	0.957	0.043
O31 Complications specific to multiple gestation	0.000	0.957	0.043
O34.4 Maternal care for other abnormalities of cervix	0.000	0.957	0.043
O32.1 Maternal care for breech presentation	0.000	0.957	0.043
O40 Polyhydramnios	0.000	0.958	0.042
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.958	0.042
O32.0 Maternal care for unstable lie	0.000	0.958	0.042
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.958	0.042
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.958	0.042
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.958	0.042
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.958	0.042
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.958	0.042
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.958	0.042
O45 Premature separation of placenta [abruptio placentae]	0.000	0.958	0.042
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.960	0.040
O44.1 Placenta praevia with haemorrhage	0.000	0.960	0.040
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.961	0.039
O33.8 Maternal care for disproportion of other origin	0.000	0.961	0.039
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.961	0.039
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.961	0.039
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.961	0.039
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.961	0.039
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.961	0.039
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.961	0.039
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.961	0.039
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.961	0.039
O43 Placental disorders	0.000	0.962	0.038
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.962	0.038
O32.6 Maternal care for compound presentation	0.000	0.962	0.037
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.963	0.037
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.963	0.036
O30 Multiple gestation	0.000	0.964	0.036
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.964	0.036
O41.0 Oligohydramnios	0.000	0.964	0.036
O32.3 Maternal care for face, brow and chin presentation	0.000	0.964	0.036
K35.8 Acute appendicitis, other and unspecified	0.034	0.966	0.000
K35.9 Acute appendicitis, unspecified	0.034	0.966	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.966	0.034
O41.1 Infection of amniotic sac and membranes	0.000	0.967	0.033
O46.8 Other antepartum haemorrhage	0.000	0.967	0.033
K35 Acute appendicitis	0.032	0.968	0.000
O31.8 Other complications specific to multiple gestation	0.000	0.969	0.031
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.969	0.031
O31.0 Papyraceous foetus	0.000	0.969	0.031
O36.4 Maternal care for intra-uterine death	0.000	0.970	0.030
O45.8 Other premature separation of placenta	0.000	0.970	0.030
O45.0 Premature separation of placenta with coagulation defect	0.000	0.970	0.030
O43.0 Placental transfusion syndromes	0.000	0.970	0.029
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.971	0.029
K35.0 Acute appendicitis with generalised peritonitis	0.028	0.972	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.972	0.028
O43.9 Placental disorder, unspecified	0.000	0.972	0.028
O43.2 Morbidly adherent placenta	0.000	0.972	0.028
A63.0 Anogenital (venereal) warts	0.027	0.973	0.000
O45.9 Premature separation of placenta, unspecified	0.000	0.973	0.027
Y60-Y69 Misadventures to patients during surgical and medical care	0.027	0.973	0.000
O30.9 Multiple gestation, unspecified	0.000	0.974	0.026
O30.8 Other multiple gestation	0.000	0.974	0.026
O30.2 Quadruplet pregnancy	0.000	0.974	0.026
O32.4 Maternal care for high head at term	0.000	0.975	0.025
O30.1 Triplet pregnancy	0.000	0.975	0.025
O43.8 Other placental disorders	0.000	0.977	0.023
O43.1 Malformation of placenta	0.000	0.977	0.023
K35.1 Acute appendicitis with peritoneal abscess	0.023	0.977	0.000
O42 Premature rupture of membranes	0.000	0.978	0.022
K35.2 Acute appendicitis with generalized peritonitis	0.020	0.980	0.000
O30.0 Twin pregnancy	0.000	0.980	0.020
Y66 Nonadministration of surgical and medical care	0.020	0.980	0.000
Y64 Contaminated medical or biological substances	0.019	0.980	0.000
Y63 Failure in dosage during surgical and medical care	0.019	0.980	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.019	0.980	0.000
Y69 Unspecified misadventure during surgical and medical care	0.019	0.980	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.019	0.981	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.981	0.019
Y61 Foreign object accidentally left in body during surgical and medical care	0.018	0.981	0.000
Y65 Other misadventures during surgical and medical care	0.018	0.982	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.983	0.017
A63.8 Other specified predominantly sexually transmitted diseases	0.016	0.984	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.985	0.015
K35-K38 Diseases of appendix	0.015	0.985	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.986	0.014
Y62.9 During unspecified surgical and medical care	0.014	0.986	0.000
Y62.8 During other surgical and medical care	0.014	0.986	0.000
Y62.6 During aspiration, puncture and other catheterisation	0.014	0.986	0.000
Y62.5 During heart catheterisation	0.014	0.986	0.000
Y62.4 During endoscopic examination	0.014	0.986	0.000
Y62.3 During injection or immunisation	0.014	0.986	0.000
Y62.2 During kidney dialysis or other perfusion	0.014	0.986	0.000
Y62.1 During infusion or transfusion	0.014	0.986	0.000
Y62.0 During surgical operation	0.014	0.986	0.000
Y63.9 Failure in dosage during unspecified surgical and medical care	0.014	0.986	0.000
Y63.8 Failure in dosage during other surgical and medical care	0.014	0.986	0.000
Y63.6 Nonadministration of necessary drug, medicament or biological substance	0.014	0.986	0.000
Y63.5 Inappropriate temperature in local application and packing	0.014	0.986	0.000
Y63.4 Failure in dosage in electroshock or insulin-shock therapy	0.014	0.986	0.000
Y63.3 Inadvertent exposure of patient to radiation during medical care	0.014	0.986	0.000
Y63.2 Overdose of radiation given during therapy	0.014	0.986	0.000
Y63.1 Incorrect dilution of fluid used during infusion	0.014	0.986	0.000
Y63.0 Excessive amount of blood or other fluid given during transfusion or infusion	0.014	0.986	0.000
Y64.9 Contaminated medical or biological substance administered by unspecified means	0.014	0.986	0.000
Y64.8 Contaminated medical or biological substance administered by other means	0.014	0.986	0.000
Y64.1 Contaminated medical or biological substance, injected or used for immunisation	0.014	0.986	0.000
Y64.0 Contaminated medical or biological substance, transfused or infused	0.014	0.986	0.000
O47 False labour	0.000	0.986	0.014
K38 Other diseases of appendix	0.014	0.986	0.000
Y61.9 During unspecified surgical and medical care	0.013	0.986	0.000
Y61.8 During other surgical and medical care	0.013	0.986	0.000
Y61.7 During removal of catheter or packing	0.013	0.986	0.000
Y61.6 During aspiration, puncture and other catheterisation	0.013	0.986	0.000
Y61.5 During heart catheterisation	0.013	0.986	0.000
Y61.4 During endoscopic examination	0.013	0.986	0.000
Y61.3 During injection or immunisation	0.013	0.986	0.000
Y61.2 During kidney dialysis or other perfusion	0.013	0.986	0.000
Y61.1 During infusion or transfusion	0.013	0.986	0.000
Y65.5 Performance of inappropriate operation	0.013	0.987	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.013	0.987	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.013	0.987	0.000
Y65.1 Wrong fluid used in infusion	0.013	0.987	0.000
Y65.0 Mismatched blood used in transfusion	0.013	0.987	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.013	0.987	0.000
K38.1 Appendicular concretions	0.013	0.987	0.000
Y61.0 During surgical operation	0.012	0.987	0.000
O26.2 Pregnancy care of habitual aborter	0.000	0.987	0.013
Y65.4 Failure to introduce or to remove other tube or instrument	0.012	0.988	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.988	0.012
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.989	0.011
O26.0 Excessive weight gain in pregnancy	0.000	0.989	0.011
O26.5 Maternal hypotension syndrome	0.000	0.989	0.011
K38.2 Diverticulum of appendix	0.011	0.989	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.989	0.011
O26.4 Herpes gestationis	0.000	0.989	0.010
O26.1 Low weight gain in pregnancy	0.000	0.989	0.010
K36 Other appendicitis	0.010	0.989	0.000
I44.0 Atrioventricular block, first degree	0.010	0.990	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.990	0.010
K38.8 Other specified diseases of appendix	0.010	0.990	0.000
L90.5 Scar conditions and fibrosis of skin	0.010	0.990	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.990	0.010
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.990	0.010
K38.3 Fistula of appendix	0.010	0.990	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.990	0.010
K35.3 Acute appendicitis with localized peritonitis	0.010	0.990	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.001	0.990	0.009
K38.0 Hyperplasia of appendix	0.009	0.990	0.000
Z37.0 Single live birth	0.000	0.990	0.010
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.991	0.009
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.991	0.009
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.009	0.991	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.991	0.009
O22 Venous complications in pregnancy	0.000	0.991	0.009
K38.9 Disease of appendix, unspecified	0.009	0.991	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.992	0.008
O25 Malnutrition in pregnancy	0.000	0.992	0.008
A50-A64 Infections with a predominantly sexual mode of transmission	0.008	0.992	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.008	0.992	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.992	0.008
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.992	0.008
K37 Unspecified appendicitis	0.008	0.992	0.000
O80-O84 Delivery	0.000	0.992	0.008
O20 Haemorrhage in early pregnancy	0.000	0.992	0.008
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.993	0.007
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.993	0.007
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.993	0.007
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.993	0.007
O21 Excessive vomiting in pregnancy	0.000	0.993	0.007
O22.4 Haemorrhoids in pregnancy	0.000	0.993	0.007
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.993	0.007
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.993	0.007
S43.0 Dislocation of shoulder joint	0.007	0.993	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.993	0.007
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.993	0.007
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.993	0.007
O82.1 Delivery by emergency Caesarean section	0.000	0.993	0.007
O81 Single delivery by forceps and vacuum extractor	0.000	0.993	0.007
O82 Single delivery by Caesarean section	0.000	0.993	0.007
O22.9 Venous complication in pregnancy, unspecified	0.000	0.993	0.006
O22.8 Other venous complications in pregnancy	0.000	0.993	0.006
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.993	0.006
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.993	0.006
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.993	0.006
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.994	0.006
O26.8 Other specified pregnancy-related conditions	0.000	0.994	0.006
O22.1 Genital varices in pregnancy	0.000	0.994	0.006
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.994	0.006
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.994	0.006
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.6 Failed or difficult intubation during pregnancy	0.000	0.994	0.006
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.994	0.006
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.994	0.006
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.994	0.006
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.994	0.006
A60 Anogenital herpesviral [herpes simplex] infections	0.006	0.994	0.000
A59 Trichomoniasis	0.006	0.994	0.000
A56 Other sexually transmitted chlamydial diseases	0.006	0.994	0.000
A54 Gonococcal infection	0.006	0.994	0.000
A53 Other and unspecified syphilis	0.006	0.994	0.000
A52 Late syphilis	0.006	0.994	0.000
A51 Early syphilis	0.006	0.994	0.000
A50 Congenital syphilis	0.006	0.994	0.000
A64 Unspecified sexually transmitted disease	0.006	0.994	0.000
A58 Granuloma inguinale	0.006	0.994	0.000
A57 Chancroid	0.006	0.994	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.006	0.994	0.000
H25.0 Senile incipient cataract	0.006	0.994	0.000
O81.4 Vacuum extractor delivery	0.000	0.994	0.006
I62 Other nontraumatic intracranial haemorrhage	0.006	0.994	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.994	0.006
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.994	0.006
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.994	0.006
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.994	0.006
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.994	0.006
O84 Multiple delivery	0.000	0.994	0.006
O21.8 Other vomiting complicating pregnancy	0.000	0.994	0.006
O81.0 Low forceps delivery	0.000	0.994	0.005
O23 Infections of genito-urinary tract in pregnancy	0.000	0.994	0.005
O81.3 Other and unspecified forceps delivery	0.000	0.994	0.005
O20.8 Other haemorrhage in early pregnancy	0.000	0.995	0.005
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.005	0.995	0.000
C09.9 Tonsil, unspecified	0.000	0.995	0.005
F32.3 Severe depressive episode with psychotic symptoms	0.005	0.995	0.000
K50.1 Crohn's disease of large intestine	0.000	0.995	0.005
O21.2 Late vomiting of pregnancy	0.000	0.995	0.005
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.995	0.005
O81.2 Mid-cavity forceps with rotation	0.000	0.995	0.005
O81.1 Mid-cavity forceps delivery	0.000	0.995	0.005
O83 Other assisted single delivery	0.000	0.995	0.005
O82.8 Other single delivery by Caesarean section	0.000	0.995	0.005
O82.2 Delivery by Caesarean hysterectomy	0.000	0.995	0.005
M80.9 Unspecified osteoporosis with pathological fracture	0.005	0.995	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.995	0.005
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O21.0 Mild hyperemesis gravidarum	0.000	0.995	0.005
K29.1 Other acute gastritis	0.000	0.995	0.005
O82.9 Delivery by Caesarean section, unspecified	0.000	0.995	0.005
I62.1 Nontraumatic extradural haemorrhage	0.005	0.995	0.000
A60.0 Herpesviral infection of genitalia and urogenital tract	0.005	0.995	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.005	0.995	0.000
A60.9 Anogenital herpesviral infection, unspecified	0.004	0.995	0.000
A60.1 Herpesviral infection of perianal skin and rectum	0.004	0.995	0.000
X51.9 Unspecified place	0.005	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.995	0.005
A50.9 Congenital syphilis, unspecified	0.004	0.995	0.000
A50.7 Late congenital syphilis, unspecified	0.004	0.995	0.000
A50.6 Late congenital syphilis, latent	0.004	0.995	0.000
A50.5 Other late congenital syphilis, symptomatic	0.004	0.995	0.000
A50.4 Late congenital neurosyphilis [juvenile neurosyphilis]	0.004	0.995	0.000
A50.3 Late congenital syphilitic oculopathy	0.004	0.995	0.000
A50.2 Early congenital syphilis, unspecified	0.004	0.995	0.000
A50.1 Early congenital syphilis, latent	0.004	0.995	0.000
A50.0 Early congenital syphilis, symptomatic	0.004	0.995	0.000
A51.9 Early syphilis, unspecified	0.004	0.995	0.000
A51.5 Early syphilis, latent	0.004	0.995	0.000
A51.4 Other secondary syphilis	0.004	0.995	0.000
A51.3 Secondary syphilis of skin and mucous membranes	0.004	0.995	0.000
A51.2 Primary syphilis of other sites	0.004	0.995	0.000
A51.1 Primary anal syphilis	0.004	0.995	0.000
A51.0 Primary genital syphilis	0.004	0.995	0.000
A52.9 Late syphilis, unspecified	0.004	0.995	0.000
A52.8 Late syphilis, latent	0.004	0.995	0.000
A52.7 Other symptomatic late syphilis	0.004	0.995	0.000
A52.3 Neurosyphilis, unspecified	0.004	0.995	0.000
A52.2 Asymptomatic neurosyphilis	0.004	0.995	0.000
A52.0 Cardiovascular syphilis	0.004	0.995	0.000
A53.9 Syphilis, unspecified	0.004	0.995	0.000
A53.0 Latent syphilis, unspecified as early or late	0.004	0.995	0.000
A54.9 Gonococcal infection, unspecified	0.004	0.995	0.000
A54.8 Other gonococcal infections	0.004	0.995	0.000
A54.6 Gonococcal infection of anus and rectum	0.004	0.995	0.000
A54.5 Gonococcal pharyngitis	0.004	0.995	0.000
A54.4 Gonococcal infection of musculoskeletal system	0.004	0.995	0.000
A54.3 Gonococcal infection of eye	0.004	0.995	0.000
A54.2 Gonococcal pelviperitonitis and other gonococcal genito-urinary infections	0.004	0.995	0.000
A54.1 Gonococcal infection of lower genito-urinary tract with periurethral and accessory gland abscess	0.004	0.995	0.000
A54.0 Gonococcal infection of lower genito-urinary tract without periurethral or accessory gland abscess	0.004	0.995	0.000
A56.8 Sexually transmitted chlamydial infection of other sites	0.004	0.995	0.000
A56.4 Chlamydial infection of pharynx	0.004	0.995	0.000
A56.3 Chlamydial infection of anus and rectum	0.004	0.995	0.000
A56.2 Chlamydial infection of genito-urinary tract, unspecified	0.004	0.995	0.000
A56.1 Chlamydial infection of pelviperitoneum and other genito-urinary organs	0.004	0.995	0.000
A56.0 Chlamydial infection of lower genito-urinary tract	0.004	0.995	0.000
A59.9 Trichomoniasis, unspecified	0.004	0.995	0.000
A59.8 Trichomoniasis of other sites	0.004	0.995	0.000
A59.0 Urogenital trichomoniasis	0.004	0.995	0.000
A52.1 Symptomatic neurosyphilis	0.004	0.995	0.000
T78.3 Angioneurotic oedema	0.005	0.995	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.004	0.996	0.000
O84.2 Multiple delivery, all by Caesarean section	0.000	0.996	0.004
O84.9 Multiple delivery, unspecified	0.000	0.996	0.004
O84.8 Other multiple delivery	0.000	0.996	0.004
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.996	0.004
O84.0 Multiple delivery, all spontaneous	0.000	0.996	0.004
N71.1 Chronic inflammatory disease of uterus	0.000	0.996	0.004
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.996	0.004
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.996	0.004
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.004	0.996	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.996	0.004
O23.2 Infections of urethra in pregnancy	0.000	0.996	0.004
O23.1 Infections of bladder in pregnancy	0.000	0.996	0.004
O23.0 Infections of kidney in pregnancy	0.000	0.996	0.004
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.004
O83.9 Assisted single delivery, unspecified	0.000	0.996	0.004
O83.8 Other specified assisted single delivery	0.000	0.996	0.004
O83.4 Destructive operation for delivery	0.000	0.996	0.004
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.996	0.004
O83.2 Other manipulation-assisted delivery	0.000	0.996	0.004
O83.0 Breech extraction	0.000	0.996	0.004
O47.9 False labour, unspecified	0.000	0.996	0.004
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.996	0.004
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.996	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.004
O15 Eclampsia	0.000	0.996	0.004
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.996	0.004
L71.1 Rhinophyma	0.000	0.996	0.004
S43.2 Dislocation of sternoclavicular joint	0.004	0.996	0.000
I44 Atrioventricular and left bundle-branch block	0.004	0.996	0.000
Z71.3 Dietary counselling and surveillance	0.004	0.996	0.000
O80 Single spontaneous delivery	0.000	0.996	0.004
Z45.1 Adjustment and management of infusion pump	0.004	0.996	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.004	0.996	0.000
I44.6 Other and unspecified fascicular block	0.004	0.996	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.996	0.003
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.996	0.003
O95 Obstetric death of unspecified cause	0.000	0.996	0.003
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.996	0.003
S43.5 Sprain and strain of acromioclavicular joint	0.003	0.996	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.996	0.004
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.996	0.003
S43.4 Sprain and strain of shoulder joint	0.003	0.996	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
C62.9 Testis, unspecified	0.003	0.996	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.997	0.003
O83.1 Other assisted breech delivery	0.000	0.997	0.003
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.997	0.000
N87.1 Moderate cervical dysplasia	0.003	0.997	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
X51 Travel and motion	0.003	0.997	0.000
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.997	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
O12.1 Gestational proteinuria	0.000	0.997	0.003
I44.4 Left anterior fascicular block	0.003	0.997	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
M25.31 Other instability of joint (Shoulder region)	0.003	0.997	0.000
I44.7 Left bundle-branch block, unspecified	0.003	0.997	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.997	0.003
F32.1 Moderate depressive episode	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
M47.86 Other spondylosis (Lumbar region)	0.000	0.997	0.003
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.003
O15.2 Eclampsia in the puerperium	0.000	0.997	0.003
O15.1 Eclampsia in labour	0.000	0.997	0.003
O15.0 Eclampsia in pregnancy	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
X51.8 Other specified place	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
I44.3 Other and unspecified atrioventricular block	0.003	0.997	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.997	0.003
O12.0 Gestational oedema	0.000	0.997	0.003
K56.7 Ileus, unspecified	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
I44.5 Left posterior fascicular block	0.003	0.997	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.997	0.003
Z73 Problems related to life-management difficulty	0.000	0.997	0.003
O85-O92 Complications predominantly related to the puerperium	0.000	0.997	0.003
O80.1 Spontaneous breech delivery	0.000	0.997	0.003
C83.3 Large cell (diffuse)	0.003	0.997	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O96.9 Death from unspecified obstetric cause	0.000	0.997	0.003
O96.1 Death from indirect obstetric cause	0.000	0.997	0.003
O96.0 Death from direct obstetric cause	0.000	0.997	0.003
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.997	0.003
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.997	0.003
O97.0 Death from sequelae of direct obstetric cause	0.000	0.997	0.003
O80.8 Other single spontaneous delivery	0.000	0.997	0.003
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O80.0 Spontaneous vertex delivery	0.000	0.997	0.003
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
F32 Depressive episode	0.003	0.997	0.000
M47.8 Other spondylosis	0.000	0.997	0.003
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
X51.7 Farm	0.003	0.997	0.000
X51.6 Industrial and construction area	0.003	0.997	0.000
X51.5 Trade and service area	0.003	0.997	0.000
X51.4 Street and highway	0.003	0.997	0.000
X51.3 Sports and athletics area	0.003	0.997	0.000
X51.2 School, other institution and public administrative area	0.003	0.997	0.000
X51.1 Residential institution	0.003	0.997	0.000
X51.0 Home	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.997	0.003
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.997	0.000
Z73.8 Other problems related to life-management difficulty	0.000	0.997	0.002
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.997	0.002
M54.9 Dorsalgia, unspecified	0.000	0.997	0.003
R23.2 Flushing	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.997	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
O88 Obstetric embolism	0.000	0.998	0.002
Z73.5 Social role conflict, not elsewhere classified	0.000	0.998	0.002
Z73.4 Inadequate social skills, not elsewhere classified	0.000	0.998	0.002
Z73.2 Lack of relaxation and leisure	0.000	0.998	0.002
Z73.1 Accentuation of personality traits	0.000	0.998	0.002
Z73.0 Burn-out	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
O00-O08 Pregnancy with abortive outcome	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O89 Complications of anaesthesia during the puerperium	0.000	0.998	0.002
O91 Infections of breast associated with childbirth	0.000	0.998	0.002
F32.8 Other depressive episodes	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.998	0.002
Z73.6 Limitation of activities due to disability	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations