TreeWAS – Variant ID: rs6449353

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65.3 Chronic mucoid otitis media	0.069	0.931	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.935	0.065
H65 Nonsuppurative otitis media	0.064	0.936	0.000
H65.4 Other chronic nonsuppurative otitis media	0.060	0.940	0.000
H73.8 Other specified disorders of tympanic membrane	0.054	0.946	0.000
H73 Other disorders of tympanic membrane	0.051	0.949	0.000
H65.2 Chronic serous otitis media	0.049	0.950	0.000
H65-H75 Diseases of middle ear and mastoid	0.049	0.951	0.000
H65.0 Acute serous otitis media	0.047	0.953	0.000
H65.1 Other acute nonsuppurative otitis media	0.046	0.954	0.000
J36 Peritonsillar abscess	0.000	0.955	0.045
H65.9 Nonsuppurative otitis media, unspecified	0.045	0.955	0.000
H74 Other disorders of middle ear and mastoid	0.044	0.956	0.000
H74.4 Polyp of middle ear	0.039	0.961	0.000
K74.6 Other and unspecified cirrhosis of liver	0.037	0.963	0.000
H73.1 Chronic myringitis	0.037	0.963	0.000
H73.0 Acute myringitis	0.037	0.963	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.037	0.963	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.036	0.963	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.035	0.965	0.000
H68 Eustachian salpingitis and obstruction	0.035	0.965	0.000
H67 Otitis media in diseases classified elsewhere	0.035	0.965	0.000
K74 Fibrosis and cirrhosis of liver	0.034	0.966	0.000
H74.0 Tympanosclerosis	0.033	0.967	0.000
H69 Other disorders of Eustachian tube	0.033	0.967	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.032	0.968	0.000
K74.3 Primary biliary cirrhosis	0.032	0.968	0.000
H74.1 Adhesive middle ear disease	0.031	0.968	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.031	0.969	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.031	0.969	0.000
H70 Mastoiditis and related conditions	0.031	0.969	0.000
K74.5 Biliary cirrhosis, unspecified	0.029	0.971	0.000
H72 Perforation of tympanic membrane	0.027	0.973	0.000
I10 Essential (primary) hypertension	0.026	0.974	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.025	0.974	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.025	0.974	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.025	0.974	0.000
H68.1 Obstruction of Eustachian tube	0.025	0.974	0.000
H68.0 Eustachian salpingitis	0.025	0.974	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.025	0.974	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.025	0.974	0.000
K74.0 Hepatic fibrosis	0.025	0.975	0.000
K74.4 Secondary biliary cirrhosis	0.025	0.975	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.025	0.975	0.000
K74.1 Hepatic sclerosis	0.025	0.975	0.000
H69.8 Other specified disorders of Eustachian tube	0.025	0.975	0.000
H69.0 Patulous Eustachian tube	0.024	0.976	0.000
H71 Cholesteatoma of middle ear	0.023	0.977	0.000
H70.8 Other mastoiditis and related conditions	0.023	0.977	0.000
H70.2 Petrositis	0.022	0.978	0.000
H70.1 Chronic mastoiditis	0.022	0.978	0.000
H70.0 Acute mastoiditis	0.022	0.978	0.000
H72.1 Attic perforation of tympanic membrane	0.021	0.979	0.000
K70-K77 Diseases of liver	0.021	0.979	0.000
H69.9 Eustachian tube disorder, unspecified	0.021	0.979	0.000
H72.2 Other marginal perforations of tympanic membrane	0.020	0.980	0.000
H72.8 Other perforations of tympanic membrane	0.019	0.981	0.000
K29.6 Other gastritis	0.019	0.981	0.000
H72.0 Central perforation of tympanic membrane	0.019	0.981	0.000
K76.8 Other specified diseases of liver	0.018	0.982	0.000
K73 Chronic hepatitis, not elsewhere classified	0.017	0.983	0.000
K76 Other diseases of liver	0.017	0.983	0.000
H70.9 Mastoiditis, unspecified	0.016	0.984	0.000
K70 Alcoholic liver disease	0.016	0.984	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.985	0.015
K77 Liver disorders in diseases classified elsewhere	0.015	0.985	0.000
K71 Toxic liver disease	0.015	0.985	0.000
K72 Hepatic failure, not elsewhere classified	0.015	0.985	0.000
H66 Suppurative and unspecified otitis media	0.015	0.985	0.000
K73.9 Chronic hepatitis, unspecified	0.015	0.985	0.000
K75 Other inflammatory liver diseases	0.015	0.985	0.000
Z90.1 Acquired absence of breast(s)	0.014	0.986	0.000
K70.3 Alcoholic cirrhosis of liver	0.013	0.987	0.000
K75.4 Autoimmune hepatitis	0.013	0.987	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.013	0.987	0.000
K76.7 Hepatorenal syndrome	0.012	0.987	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.012	0.987	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.012	0.987	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.012	0.987	0.000
K72.0 Acute and subacute hepatic failure	0.012	0.988	0.000
K76.5 Hepatic veno-occlusive disease	0.012	0.988	0.000
K76.4 Peliosis hepatis	0.012	0.988	0.000
K76.3 Infarction of liver	0.012	0.988	0.000
K76.2 Central haemorrhagic necrosis of liver	0.012	0.988	0.000
K76.1 Chronic passive congestion of liver	0.012	0.988	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.988	0.012
K72.1 Chronic hepatic failure	0.012	0.988	0.000
M25.37 Other instability of joint (Ankle and foot)	0.012	0.988	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.011	0.989	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.011	0.989	0.000
K70.0 Alcoholic fatty liver	0.011	0.989	0.000
K75.8 Other specified inflammatory liver diseases	0.011	0.989	0.000
K70.1 Alcoholic hepatitis	0.011	0.989	0.000
K71.9 Toxic liver disease, unspecified	0.011	0.989	0.000
K71.8 Toxic liver disease with other disorders of liver	0.011	0.989	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.011	0.989	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.011	0.989	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.011	0.989	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.011	0.989	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.011	0.989	0.000
K71.2 Toxic liver disease with acute hepatitis	0.011	0.989	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.011	0.989	0.000
K71.0 Toxic liver disease with cholestasis	0.011	0.989	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.011	0.989	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.011	0.989	0.000
H66.0 Acute suppurative otitis media	0.011	0.989	0.000
M51 Other intervertebral disk disorders	0.000	0.989	0.011
K75.2 Nonspecific reactive hepatitis	0.011	0.989	0.000
K75.1 Phlebitis of portal vein	0.011	0.989	0.000
M25.46 Effusion of joint (Lower leg)	0.011	0.989	0.000
K70.4 Alcoholic hepatic failure	0.010	0.990	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.010	0.990	0.000
H66.4 Suppurative otitis media, unspecified	0.010	0.990	0.000
K76.6 Portal hypertension	0.010	0.990	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.010	0.990	0.000
M25.3 Other instability of joint	0.010	0.990	0.000
Z01.8 Other specified special examinations	0.010	0.990	0.000
Z90.0 Acquired absence of part of head and neck	0.009	0.991	0.000
K75.0 Abscess of liver	0.009	0.991	0.000
M25.4 Effusion of joint	0.009	0.991	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.991	0.009
K76.9 Liver disease, unspecified	0.009	0.991	0.000
M51.4 Schmorl's nodes	0.000	0.991	0.009
K70.9 Alcoholic liver disease, unspecified	0.008	0.992	0.000
M67.8 Other specified disorders of synovium and tendon	0.008	0.992	0.000
M25.42 Effusion of joint (Upper arm)	0.008	0.992	0.000
M25 Other joint disorders, not elsewhere classified	0.008	0.992	0.000
M51.3 Other specified intervertebral disk degeneration	0.000	0.992	0.008
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.992	0.008
K75.9 Inflammatory liver disease, unspecified	0.008	0.992	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.992	0.000
Chapter VIII Diseases of the ear and mastoid process	0.008	0.992	0.000
K72.9 Hepatic failure, unspecified	0.008	0.992	0.000
M25.31 Other instability of joint (Shoulder region)	0.007	0.993	0.000
M25.9 Joint disorder, unspecified	0.007	0.993	0.000
I89.0 Lymphoedema, not elsewhere classified	0.007	0.993	0.000
M25.36 Other instability of joint (Lower leg)	0.007	0.993	0.000
M25.44 Effusion of joint (Hand)	0.007	0.993	0.000
M25.39 Other instability of joint (Site unspecified)	0.007	0.993	0.000
M25.38 Other instability of joint (Other)	0.007	0.993	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.007	0.993	0.000
M25.32 Other instability of joint (Upper arm)	0.007	0.993	0.000
M25.30 Other instability of joint (Multiple sites)	0.007	0.993	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.007	0.993	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.993	0.007
M25.34 Other instability of joint (Hand)	0.007	0.993	0.000
S62.50 Fracture of thumb (closed)	0.007	0.993	0.000
M25.33 Other instability of joint (Forearm)	0.007	0.993	0.000
M25.49 Effusion of joint (Site unspecified)	0.007	0.993	0.000
M25.48 Effusion of joint (Other)	0.007	0.993	0.000
M25.41 Effusion of joint (Shoulder region)	0.007	0.993	0.000
Z45 Adjustment and management of implanted device	0.000	0.993	0.007
M25.45 Effusion of joint (Pelvic region and thigh)	0.006	0.993	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.006	0.993	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.006	0.993	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.006	0.994	0.000
M25.8 Other specified joint disorders	0.006	0.994	0.000
H43.3 Other vitreous opacities	0.006	0.994	0.000
M25.0 Haemarthrosis	0.006	0.994	0.000
H66.9 Otitis media, unspecified	0.006	0.994	0.000
M25.2 Flail joint	0.006	0.994	0.000
M25.1 Fistula of joint	0.006	0.994	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.994	0.006
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.994	0.006
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.994	0.006
M25.40 Effusion of joint (Multiple sites)	0.006	0.994	0.000
S62.70 Multiple fractures of fingers (closed)	0.006	0.994	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
S62.5 Fracture of thumb	0.006	0.994	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.006	0.994	0.000
M25.71 Osteophyte (Shoulder region)	0.006	0.994	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.994	0.006
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M25.43 Effusion of joint (Forearm)	0.005	0.994	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.005	0.994	0.000
M25.98 Joint disorder, unspecified (Other)	0.005	0.994	0.000
M25.94 Joint disorder, unspecified (Hand)	0.005	0.994	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.005	0.994	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.005	0.994	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.006	0.994	0.000
N64.8 Other specified disorders of breast	0.006	0.994	0.000
H60-H62 Diseases of external ear	0.006	0.994	0.000
Z45.3 Adjustment and management of implanted hearing device	0.000	0.994	0.005
M25.7 Osteophyte	0.006	0.994	0.000
H43.1 Vitreous haemorrhage	0.006	0.994	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.006	0.994	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.005	0.994	0.000
S62.7 Multiple fractures of fingers	0.005	0.994	0.000
M25.72 Osteophyte (Upper arm)	0.005	0.995	0.000
S62.2 Fracture of first metacarpal bone	0.005	0.995	0.000
H43 Disorders of vitreous body	0.005	0.995	0.000
S62 Fracture at wrist and hand level	0.005	0.995	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M25.88 Other specified joint disorders (Other)	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M25.83 Other specified joint disorders (Forearm)	0.005	0.995	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.005	0.995	0.000
M25.86 Other specified joint disorders (Lower leg)	0.005	0.995	0.000
M25.84 Other specified joint disorders (Hand)	0.005	0.995	0.000
Z34 Supervision of normal pregnancy	0.000	0.995	0.005
M25.89 Other specified joint disorders (Site unspecified)	0.005	0.995	0.000
M25.82 Other specified joint disorders (Upper arm)	0.005	0.995	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.005	0.995	0.000
S62.51 Fracture of thumb (open)	0.005	0.995	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.995	0.004
H60.8 Other otitis externa	0.005	0.995	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.995	0.005
M25.09 Haemarthrosis (Site unspecified)	0.005	0.995	0.000
M25.08 Haemarthrosis (Other)	0.005	0.995	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.005	0.995	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.005	0.995	0.000
M25.04 Haemarthrosis (Hand)	0.005	0.995	0.000
M25.03 Haemarthrosis (Forearm)	0.005	0.995	0.000
M25.02 Haemarthrosis (Upper arm)	0.005	0.995	0.000
M25.01 Haemarthrosis (Shoulder region)	0.005	0.995	0.000
M25.00 Haemarthrosis (Multiple sites)	0.005	0.995	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.005	0.995	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.995	0.005
M25.06 Haemarthrosis (Lower leg)	0.005	0.995	0.000
M25.19 Fistula of joint (Site unspecified)	0.004	0.995	0.000
M25.18 Fistula of joint (Other)	0.004	0.995	0.000
M25.17 Fistula of joint (Ankle and foot)	0.004	0.995	0.000
M25.16 Fistula of joint (Lower leg)	0.004	0.995	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.14 Fistula of joint (Hand)	0.004	0.995	0.000
M25.13 Fistula of joint (Forearm)	0.004	0.995	0.000
M25.12 Fistula of joint (Upper arm)	0.004	0.995	0.000
M25.11 Fistula of joint (Shoulder region)	0.004	0.995	0.000
M25.10 Fistula of joint (Multiple sites)	0.004	0.995	0.000
M25.29 Flail joint (Site unspecified)	0.004	0.995	0.000
M25.28 Flail joint (Other)	0.004	0.995	0.000
M25.27 Flail joint (Ankle and foot)	0.004	0.995	0.000
M25.26 Flail joint (Lower leg)	0.004	0.995	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.24 Flail joint (Hand)	0.004	0.995	0.000
M25.23 Flail joint (Forearm)	0.004	0.995	0.000
M25.22 Flail joint (Upper arm)	0.004	0.995	0.000
M25.21 Flail joint (Shoulder region)	0.004	0.995	0.000
M25.20 Flail joint (Multiple sites)	0.004	0.995	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.004	0.995	0.000
H43.8 Other disorders of vitreous body	0.005	0.995	0.000
M25.76 Osteophyte (Lower leg)	0.005	0.995	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.995	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.995	0.005
H60.1 Cellulitis of external ear	0.004	0.995	0.000
I22 Subsequent myocardial infarction	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.004	0.996	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
M25.79 Osteophyte (Site unspecified)	0.004	0.996	0.000
M25.73 Osteophyte (Forearm)	0.004	0.996	0.000
M25.70 Osteophyte (Multiple sites)	0.004	0.996	0.000
S62.71 Multiple fractures of fingers (open)	0.004	0.996	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.004	0.996	0.000
I22.8 Subsequent myocardial infarction of other sites	0.004	0.996	0.000
S62.4 Multiple fractures of metacarpal bones	0.004	0.996	0.000
S62.21 Fracture of first metacarpal bone (open)	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.004	0.996	0.000
H43.2 Crystalline deposits in vitreous body	0.004	0.996	0.000
H43.0 Vitreous prolapse	0.004	0.996	0.000
H92.1 Otorrhoea	0.004	0.996	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.004	0.996	0.000
I85.9 Oesophageal varices without bleeding	0.004	0.996	0.000
S62.1 Fracture of other carpal bone(s)	0.004	0.996	0.000
M67 Other disorders of synovium and tendon	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
H60.0 Abscess of external ear	0.004	0.996	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.004	0.996	0.000
M25.47 Effusion of joint (Ankle and foot)	0.003	0.996	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.004	0.996	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.004	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
I10-I15 Hypertensive diseases	0.004	0.996	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.996	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.004	0.996	0.000
Z90.5 Acquired absence of kidney	0.004	0.996	0.000
I21.4 Acute subendocardial myocardial infarction	0.004	0.996	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.003	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.003	0.997	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H62.2 Otitis externa in mycoses	0.003	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.003	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.003	0.997	0.000
M25.78 Osteophyte (Other)	0.003	0.997	0.000
H43.9 Disorder of vitreous body, unspecified	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.003	0.997	0.000
K29.1 Other acute gastritis	0.003	0.997	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.003	0.997	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.997	0.003
S62.11 Fracture of other carpal bone(s) (open)	0.003	0.997	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.003	0.997	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.003	0.997	0.000
M67.3 Transient synovitis	0.003	0.997	0.000
M67.0 Short Achilles tendon (acquired)	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
M34 Systemic sclerosis	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.003	0.997	0.000
K29 Gastritis and duodenitis	0.003	0.997	0.000
M20-M25 Other joint disorders	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
M67.4 Ganglion	0.003	0.997	0.000
I21 Acute myocardial infarction	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
I13 Hypertensive heart and renal disease	0.003	0.997	0.000
I85 Oesophageal varices	0.003	0.997	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.003	0.997	0.000
G44.2 Tension-type headache	0.003	0.997	0.000
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.997	0.003
M24 Other specific joint derangements	0.003	0.997	0.000
Z90.3 Acquired absence of part of stomach	0.003	0.997	0.000
H61 Other disorders of external ear	0.003	0.997	0.000
M31 Other necrotising vasculopathies	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.003
H61.0 Perichondritis of external ear	0.003	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
K29.0 Acute haemorrhagic gastritis	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.997	0.000
W13.9 Unspecified place	0.000	0.997	0.003
C50.5 Lower-outer quadrant of breast	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
K44 Diaphragmatic hernia	0.003	0.997	0.000
M33 Dermatopolymyositis	0.003	0.997	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
M24.7 Protrusio acetabuli	0.002	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.003	0.997	0.000
S62.6 Fracture of other finger	0.003	0.997	0.000
M23 Internal derangement of knee	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.997	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.002	0.997	0.000
M24.2 Disorder of ligament	0.002	0.997	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.997	0.000
M34.0 Progressive systemic sclerosis	0.002	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
K29.2 Alcoholic gastritis	0.002	0.998	0.000
M33.2 Polymyositis	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
K29.9 Gastroduodenitis, unspecified	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.002	0.998	0.000
M32 Systemic lupus erythematosus	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
I11 Hypertensive heart disease	0.002	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
M23.0 Cystic meniscus	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.002	0.998	0.000
M23.1 Discoid meniscus (congenital)	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.002	0.998	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.002	0.998	0.000
L91.0 Keloid scar	0.002	0.998	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
I15 Secondary hypertension	0.002	0.998	0.001
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
M30 Polyarteritis nodosa and related conditions	0.002	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
K44.1 Diaphragmatic hernia with gangrene	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.002	0.998	0.000
M33.9 Dermatopolymyositis, unspecified	0.002	0.998	0.000
M33.0 Juvenile dermatomyositis	0.002	0.998	0.000
I20-I25 Ischaemic heart diseases	0.002	0.998	0.000
M23.5 Chronic instability of knee	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
D41.0 Kidney	0.002	0.998	0.000
K29.4 Chronic atrophic gastritis	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
R49.0 Dysphonia	0.000	0.998	0.002
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
D36.7 Other specified sites	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.001	0.998	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.002	0.998	0.000
M32.8 Other forms of systemic lupus erythematosus	0.002	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.002	0.998	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.002	0.998	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.002	0.998	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.002	0.998	0.000
M36.3 Arthropathy in other blood disorders	0.002	0.998	0.000
M36.2 Haemophilic arthropathy	0.002	0.998	0.000
M36.1 Arthropathy in neoplastic disease	0.002	0.998	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations