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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6492255
log Bayes Factor = 6.1559
Chromosome 13   position 110,953,717  (GRCh37) Explore rs6492255 on Ensembl!
Variant rs6492255 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.980 0.020 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.979 0.021 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.973 0.027 0.000
R26 Abnormalities of gait and mobility
0.972 0.028 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.971 0.029 0.000
R50-R69 General symptoms and signs
0.966 0.034 0.000
A00-A09 Intestinal infectious diseases
0.965 0.035 0.000
E86 Volume depletion
0.965 0.035 0.000
B95-B98 Bacterial, viral and other infectious agents
0.965 0.035 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.962 0.038 0.000
R50 Fever of unknown origin
0.955 0.045 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.947 0.053 0.000
E29 Testicular dysfunction
0.942 0.058 0.000
R50.9 Fever, unspecified
0.941 0.059 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.938 0.062 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.932 0.068 0.000
G90-G99 Other disorders of the nervous system
0.931 0.069 0.000
E23 Hypofunction and other disorders of pituitary gland
0.926 0.074 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.926 0.074 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.921 0.079 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.920 0.080 0.000
E27 Other disorders of adrenal gland
0.919 0.081 0.000
Chapter VII Diseases of the eye and adnexa
0.913 0.087 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.905 0.095 0.000
E29.1 Testicular hypofunction
0.903 0.097 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.900 0.100 0.000
G35 Multiple sclerosis
0.898 0.102 0.000
B35-B49 Mycoses
0.898 0.102 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.893 0.107 0.000
S32 Fracture of lumbar spine and pelvis
0.886 0.114 0.000
H18 Other disorders of cornea
0.882 0.118 0.000
Chapter V Mental and behavioural disorders
0.875 0.125 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.874 0.126 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.870 0.130 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.868 0.132 0.000
S90-S99 Injuries to the ankle and foot
0.866 0.134 0.000
G93 Other disorders of brain
0.865 0.135 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.860 0.140 0.000
S32.0 Fracture of lumbar vertebra
0.859 0.141 0.000
G57 Mononeuropathies of lower limb
0.856 0.144 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.856 0.144 0.000
H18.4 Corneal degeneration
0.855 0.145 0.000
Chapter IX Diseases of the circulatory system
0.855 0.145 0.000
E00-E07 Disorders of thyroid gland
0.855 0.145 0.000
H43-H45 Disorders of vitreous body and globe
0.854 0.146 0.000
G57.6 Lesion of plantar nerve
0.853 0.147 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.852 0.148 0.000
Chapter X Diseases of the respiratory system
0.851 0.149 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.850 0.150 0.000
R52 Pain, not elsewhere classified
0.850 0.150 0.000
R50.8 Other specified fever
0.849 0.151 0.000
R25 Abnormal involuntary movements
0.847 0.153 0.000
G20-G26 Extrapyramidal and movement disorders
0.845 0.155 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.844 0.156 0.000
G91 Hydrocephalus
0.843 0.157 0.000
E50-E64 Other nutritional deficiencies
0.843 0.157 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.841 0.159 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.840 0.160 0.000
E27.1 Primary adrenocortical insufficiency
0.838 0.162 0.000
Q60-Q64 Congenital malformations of the urinary system
0.832 0.168 0.000
Y42.7 Androgens and anabolic congeners
0.830 0.170 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.829 0.171 0.000
A08 Viral and other specified intestinal infections
0.826 0.174 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.826 0.174 0.000
J84 Other interstitial pulmonary diseases
0.825 0.175 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.819 0.181 0.000
E40-E46 Malnutrition
0.819 0.181 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.819 0.181 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.818 0.182 0.000
E10-E14 Diabetes mellitus
0.817 0.183 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.817 0.183 0.000
B37 Candidiasis
0.816 0.184 0.000
R61 Hyperhidrosis
0.816 0.184 0.000
I74 Arterial embolism and thrombosis
0.815 0.185 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.815 0.185 0.000
R94 Abnormal results of function studies
0.813 0.187 0.000
Y52 Agents primarily affecting the cardiovascular system
0.813 0.187 0.000
R53 Malaise and fatigue
0.810 0.190 0.000
A80-A89 Viral infections of the central nervous system
0.809 0.191 0.000
E34 Other endocrine disorders
0.808 0.192 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.808 0.192 0.000
Y57 Other and unspecified drugs and medicaments
0.807 0.193 0.000
H20 Iridocyclitis
0.805 0.195 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.805 0.195 0.000
W00-W19 Falls
0.803 0.197 0.000
E23.2 Diabetes insipidus
0.802 0.198 0.000
A07 Other protozoal intestinal diseases
0.800 0.200 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.796 0.204 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.795 0.205 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.793 0.207 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.793 0.207 0.000
Q00-Q07 Congenital malformations of the nervous system
0.788 0.212 0.000
I71 Aortic aneurysm and dissection
0.786 0.214 0.000
E22 Hyperfunction of pituitary gland
0.782 0.217 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.782 0.218 0.000
A05 Other bacterial foodborne intoxications
0.782 0.218 0.000
Y00-Y09 Assault
0.779 0.221 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.778 0.222 0.000
R54 Senility
0.778 0.222 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.777 0.223 0.000
H44 Disorders of globe
0.777 0.223 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.776 0.224 0.000
I72 Other aneurysm
0.776 0.224 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.776 0.224 0.000
S31 Open wound of abdomen, lower back and pelvis
0.776 0.224 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.776 0.224 0.000
R60 Oedema, not elsewhere classified
0.775 0.225 0.000
E79 Disorders of purine and pyrimidine metabolism
0.774 0.226 0.000
Chapter VIII Diseases of the ear and mastoid process
0.772 0.228 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.771 0.229 0.000
R52.2 Other chronic pain
0.771 0.229 0.000
E85 Amyloidosis
0.768 0.232 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.766 0.234 0.000
B50-B64 Protozoal diseases
0.766 0.234 0.000
R26.0 Ataxic gait
0.765 0.235 0.000
G91.9 Hydrocephalus, unspecified
0.765 0.235 0.000
Q35-Q37 Cleft lip and cleft palate
0.764 0.236 0.000
R26.3 Immobility
0.762 0.238 0.000
S92 Fracture of foot, except ankle
0.759 0.241 0.000
Y44 Agents primarily affecting blood constituents
0.759 0.241 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.757 0.243 0.000
E23.0 Hypopituitarism
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.752 0.248 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.749 0.251 0.000
X10-X19 Contact with heat and hot substances
0.749 0.251 0.000
R64 Cachexia
0.748 0.252 0.000
F10.1 Harmful use
0.748 0.252 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.747 0.252 0.000
G93.6 Cerebral oedema
0.747 0.253 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.747 0.253 0.000
A65-A69 Other spirochaetal diseases
0.747 0.253 0.000
R29.6 Tendency to fall, not elsewhere classified
0.746 0.254 0.000
T00-T07 Injuries involving multiple body regions
0.745 0.255 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.744 0.256 0.000
W50-W64 Exposure to animate mechanical forces
0.742 0.258 0.000
E03 Other hypothyroidism
0.741 0.259 0.000
G24 Dystonia
0.741 0.259 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.741 0.259 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.740 0.260 0.000
G93.8 Other specified disorders of brain
0.740 0.260 0.000
E53 Deficiency of other B group vitamins
0.739 0.261 0.000
B49 Unspecified mycosis
0.737 0.263 0.000
S70-S79 Injuries to the hip and thigh
0.737 0.263 0.000
B00 Herpesviral [herpes simplex] infections
0.736 0.264 0.000
E05.9 Thyrotoxicosis, unspecified
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.736 0.264 0.000
I85 Oesophageal varices
0.735 0.265 0.000
E20 Hypoparathyroidism
0.734 0.266 0.000
B99-B99 Other infectious diseases
0.732 0.268 0.000
E11 Non-insulin-dependent diabetes mellitus
0.732 0.268 0.000
J20-J22 Other acute lower respiratory infections
0.732 0.268 0.000
E23.7 Disorder of pituitary gland, unspecified
0.732 0.268 0.000
Y48 Anaesthetics and therapeutic gases
0.730 0.270 0.000
S90 Superficial injury of ankle and foot
0.729 0.270 0.000
G93.9 Disorder of brain, unspecified
0.728 0.272 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.728 0.272 0.000
Q50-Q56 Congenital malformations of genital organs
0.727 0.273 0.000
X50-X57 Overexertion, travel and privation
0.726 0.274 0.000
E28 Ovarian dysfunction
0.726 0.274 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.726 0.274 0.000
R56 Convulsions, not elsewhere classified
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
B37.3 Candidiasis of vulva and vagina
0.722 0.278 0.000
H44.2 Degenerative myopia
0.722 0.278 0.000
E88 Other metabolic disorders
0.722 0.278 0.000
V40-V49 Car occupant injured in transport accident
0.722 0.278 0.000
G30-G32 Other degenerative diseases of the nervous system
0.721 0.279 0.000
R57 Shock, not elsewhere classified
0.721 0.279 0.000
G93.2 Benign intracranial hypertension
0.721 0.279 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.720 0.279 0.000
F11 Mental and behavioural disorders due to use of opioids
0.720 0.280 0.000
H43 Disorders of vitreous body
0.720 0.280 0.000
F10.0 Acute intoxication
0.719 0.281 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.719 0.281 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.719 0.281 0.000
B37.9 Candidiasis, unspecified
0.718 0.282 0.000
B07 Viral warts
0.718 0.282 0.000
R55 Syncope and collapse
0.718 0.282 0.000
I85.9 Oesophageal varices without bleeding
0.717 0.283 0.000
R94.5 Abnormal results of liver function studies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.717 0.283 0.000
E24 Cushing's syndrome
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E31 Polyglandular dysfunction
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
E25 Adrenogenital disorders
0.715 0.285 0.000
T21 Burn and corrosion of trunk
0.715 0.285 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.712 0.288 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.712 0.288 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.711 0.289 0.000
G57.5 Tarsal tunnel syndrome
0.711 0.289 0.000
R25.1 Tremor, unspecified
0.710 0.290 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.710 0.290 0.000
A02 Other Salmonella infections
0.710 0.290 0.000
H20.9 Iridocyclitis, unspecified
0.710 0.290 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.710 0.290 0.000
E27.9 Disorder of adrenal gland, unspecified
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.293 0.000
Y10-Y34 Event of undetermined intent
0.706 0.293 0.000
X85-X99 Assault
0.706 0.293 0.000
X30-X39 Exposure to forces of nature
0.706 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.293 0.000
W75-W84 Other accidental threats to breathing
0.706 0.293 0.000
W65-W74 Accidental drowning and submersion
0.706 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.293 0.000
V95-V97 Air and space transport accidents
0.706 0.293 0.000
V90-V94 Water transport accidents
0.706 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.293 0.000
H18.5 Hereditary corneal dystrophies
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
R90.0 Intracranial space-occupying lesion
0.705 0.295 0.000
S00-S09 Injuries to the head
0.704 0.296 0.000
E23.6 Other disorders of pituitary gland
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
A04 Other bacterial intestinal infections
0.703 0.297 0.000
G95 Other diseases of spinal cord
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.297 0.000
Y58 Bacterial vaccines
0.702 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.297 0.000
R29.4 Clicking hip
0.702 0.298 0.000
R29.3 Abnormal posture
0.702 0.298 0.000
R29.2 Abnormal reflex
0.702 0.298 0.000
R29.1 Meningismus
0.702 0.298 0.000
R29.0 Tetany
0.702 0.298 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.702 0.298 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.702 0.298 0.000
F02 Dementia in other diseases classified elsewhere
0.702 0.298 0.000
Q80-Q89 Other congenital malformations
0.701 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
R26.1 Paralytic gait
0.697 0.303 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.696 0.304 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.696 0.304 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.695 0.304 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.694 0.306 0.000
H90-H95 Other disorders of ear
0.694 0.306 0.000
Q61 Cystic kidney disease
0.693 0.307 0.000
T23 Burn and corrosion of wrist and hand
0.693 0.307 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.692 0.308 0.000
R62 Lack of expected normal physiological development
0.692 0.308 0.000
A06 Amoebiasis
0.692 0.308 0.000
A03 Shigellosis
0.692 0.308 0.000
A01 Typhoid and paratyphoid fevers
0.692 0.308 0.000
A00 Cholera
0.692 0.308 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.691 0.309 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.690 0.310 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.690 0.310 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.690 0.310 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.689 0.311 0.000
E46 Unspecified protein-energy malnutrition
0.689 0.311 0.000
H18.8 Other specified disorders of cornea
0.688 0.312 0.000
F17.2 Dependence syndrome
0.688 0.312 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.687 0.313 0.000
R50.2 Drug-induced fever
0.684 0.316 0.000
R50.1 Persistent fever
0.684 0.316 0.000
E11.3 With ophthalmic complications
0.684 0.316 0.000
E83 Disorders of mineral metabolism
0.684 0.316 0.000
E87.2 Acidosis
0.683 0.317 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.682 0.318 0.000
E27.2 Addisonian crisis
0.682 0.318 0.000
A07.1 Giardiasis [lambliasis]
0.682 0.318 0.000
G24.9 Dystonia, unspecified
0.681 0.319 0.000
J09-J18 Influenza and pneumonia
0.681 0.319 0.000
E74 Other disorders of carbohydrate metabolism
0.681 0.319 0.000
Y49.2 Other and unspecified antidepressants
0.680 0.320 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.679 0.321 0.000
I74.8 Embolism and thrombosis of other arteries
0.678 0.322 0.000
H17 Corneal scars and opacities
0.678 0.322 0.000
E73 Lactose intolerance
0.676 0.323 0.000
H16 Keratitis
0.676 0.324 0.000
E29.9 Testicular dysfunction, unspecified
0.676 0.324 0.000
E29.8 Other testicular dysfunction
0.676 0.324 0.000
E29.0 Testicular hyperfunction
0.676 0.324 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.325 0.000
B36 Other superficial mycoses
0.675 0.325 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.675 0.325 0.000
E87.0 Hyperosmolality and hypernatraemia
0.674 0.326 0.000
R61.9 Hyperhidrosis, unspecified
0.674 0.326 0.000
E34.8 Other specified endocrine disorders
0.673 0.327 0.000
I86 Varicose veins of other sites
0.673 0.327 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.672 0.328 0.000
E80.6 Other disorders of bilirubin metabolism
0.670 0.330 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.669 0.330 0.000
R25.2 Cramp and spasm
0.669 0.331 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.668 0.331 0.000
G36 Other acute disseminated demyelination
0.668 0.332 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.668 0.332 0.000
G96 Other disorders of central nervous system
0.668 0.332 0.000
G20 Parkinson's disease
0.668 0.332 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.668 0.332 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.668 0.332 0.000
G92 Toxic encephalopathy
0.668 0.332 0.000
B65-B83 Helminthiases
0.667 0.333 0.000
G54 Nerve root and plexus disorders
0.667 0.333 0.000
R52.0 Acute pain
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
I05-I09 Chronic rheumatic heart diseases
0.665 0.335 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.664 0.336 0.000
E23.1 Drug-induced hypopituitarism
0.664 0.336 0.000
E53.8 Deficiency of other specified B group vitamins
0.664 0.336 0.000
S60-S69 Injuries to the wrist and hand
0.664 0.336 0.000
Q43 Other congenital malformations of intestine
0.664 0.336 0.000
T33-T35 Frostbite
0.664 0.336 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.664 0.336 0.000
I70 Atherosclerosis
0.664 0.336 0.000
H30-H36 Disorders of choroid and retina
0.663 0.337 0.000
G57.3 Lesion of lateral popliteal nerve
0.663 0.337 0.000
A08.4 Viral intestinal infection, unspecified
0.663 0.337 0.000
Q74 Other congenital malformations of limb(s)
0.663 0.337 0.000
Y46.2 Hydantoin derivatives
0.662 0.338 0.000
H93 Other disorders of ear, not elsewhere classified
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.662 0.338 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.662 0.338 0.000
R68 Other general symptoms and signs
0.661 0.339 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.660 0.340 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.660 0.340 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.659 0.341 0.000
S37 Injury of urinary and pelvic organs
0.659 0.341 0.000
S36 Injury of intra-abdominal organs
0.659 0.341 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.659 0.341 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.659 0.341 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.659 0.341 0.000
S91 Open wound of ankle and foot
0.659 0.341 0.000
E27.5 Adrenomedullary hyperfunction
0.659 0.341 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.659 0.341 0.000
E27.0 Other adrenocortical overactivity
0.659 0.341 0.000
G00 Bacterial meningitis, not elsewhere classified
0.659 0.341 0.000
E26 Hyperaldosteronism
0.658 0.342 0.000
H21 Other disorders of iris and ciliary body
0.658 0.342 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.343 0.000
Y57.9 Drug or medicament, unspecified
0.657 0.343 0.000
S00 Superficial injury of head
0.656 0.344 0.000
G70-G73 Diseases of myoneural junction and muscle
0.655 0.345 0.000
R60.0 Localised oedema
0.654 0.346 0.000
S32.3 Fracture of ilium
0.654 0.346 0.000
Q63 Other congenital malformations of kidney
0.654 0.346 0.000
S92.3 Fracture of metatarsal bone
0.654 0.346 0.000
W07 Fall involving chair
0.654 0.346 0.000
V10-V19 Pedal cyclist injured in transport accident
0.654 0.346 0.000
E11.2 With renal complications
0.653 0.347 0.000
G91.1 Obstructive hydrocephalus
0.653 0.347 0.000
R25.3 Fasciculation
0.652 0.348 0.000
Y43 Primarily systemic agents
0.652 0.348 0.000
J22 Unspecified acute lower respiratory infection
0.651 0.349 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.651 0.349 0.000
W18 Other fall on same level
0.650 0.350 0.000
A05.9 Bacterial foodborne intoxication, unspecified
0.650 0.350 0.000
I85.0 Oesophageal varices with bleeding
0.650 0.350 0.000
I72.8 Aneurysm of other specified arteries
0.650 0.350 0.000
S31.1 Open wound of abdominal wall
0.649 0.350 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.649 0.351 0.000
H15 Disorders of sclera
0.649 0.351 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.648 0.352 0.000
Q39 Congenital malformations of oesophagus
0.647 0.353 0.000
S32.4 Fracture of acetabulum
0.647 0.353 0.000
S30.2 Contusion of external genital organs
0.646 0.354 0.000
R94.6 Abnormal results of thyroid function studies
0.646 0.354 0.000
E27.8 Other specified disorders of adrenal gland
0.645 0.355 0.000
B48 Other mycoses, not elsewhere classified
0.644 0.356 0.000
B47 Mycetoma
0.644 0.356 0.000
B46 Zygomycosis
0.644 0.356 0.000
B45 Cryptococcosis
0.644 0.356 0.000
B43 Chromomycosis and phaeomycotic abscess
0.644 0.356 0.000
B42 Sporotrichosis
0.644 0.356 0.000
B41 Paracoccidioidomycosis
0.644 0.356 0.000
B40 Blastomycosis
0.644 0.356 0.000
B39 Histoplasmosis
0.644 0.356 0.000
B38 Coccidioidomycosis
0.644 0.356 0.000
G93.0 Cerebral cysts
0.643 0.357 0.000
A87 Viral meningitis
0.643 0.357 0.000
Y40.9 Systemic antibiotic, unspecified
0.642 0.358 0.000
F60-F69 Disorders of adult personality and behaviour
0.641 0.359 0.000
R61.0 Localised hyperhidrosis
0.641 0.359 0.000
Y42.9 Other and unspecified hormone antagonists
0.641 0.359 0.000
Y42.4 Oral contraceptives
0.641 0.359 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.641 0.359 0.000
Y42.2 Antithyroid drugs
0.641 0.359 0.000
Y42.1 Thyroid hormones and substitutes
0.641 0.359 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.640 0.360 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.638 0.362 0.000
I81 Portal vein thrombosis
0.638 0.362 0.000
H93.1 Tinnitus
0.637 0.363 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.636 0.363 0.000
F10.9 Unspecified mental and behavioural disorder
0.636 0.364 0.000
S32.2 Fracture of coccyx
0.635 0.365 0.000
S32.1 Fracture of sacrum
0.635 0.365 0.000
E14 Unspecified diabetes mellitus
0.635 0.365 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.635 0.365 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.634 0.366 0.000
B37.1 Pulmonary candidiasis
0.633 0.367 0.000
W08 Fall involving other furniture
0.633 0.367 0.000
F80-F89 Disorders of psychological development
0.633 0.367 0.000
H18.9 Disorder of cornea, unspecified
0.632 0.368 0.000
H18.7 Other corneal deformities
0.632 0.368 0.000
H18.3 Changes in corneal membranes
0.632 0.368 0.000
H18.2 Other corneal oedema
0.632 0.368 0.000
H18.1 Bullous keratopathy
0.632 0.368 0.000
H18.0 Corneal pigmentations and deposits
0.632 0.368 0.000
Y53.4 Other laxatives
0.631 0.369 0.000
Y54.3 Benzothiadiazine derivatives
0.630 0.370 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.628 0.372 0.000
E55 Vitamin D deficiency
0.628 0.372 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.627 0.372 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.627 0.372 0.000
F70-F79 Mental retardation
0.627 0.372 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.627 0.373 0.000
B06 Rubella [German measles]
0.626 0.373 0.000
B05 Measles
0.626 0.373 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.626 0.373 0.000
B04 Monkeypox
0.626 0.373 0.000
B03 Smallpox
0.626 0.373 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.625 0.375 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.625 0.375 0.000
X58 Exposure to other specified factors
0.625 0.375 0.000
E80.4 Gilbert's syndrome
0.624 0.376 0.000
E21.3 Hyperparathyroidism, unspecified
0.624 0.376 0.000
I78 Diseases of capillaries
0.623 0.376 0.000
E87.4 Mixed disorder of acid-base balance
0.622 0.378 0.000
A86 Unspecified viral encephalitis
0.622 0.378 0.000
F10.4 Withdrawal state with delirium
0.621 0.379 0.000
S98 Traumatic amputation of ankle and foot
0.621 0.379 0.000
S97 Crushing injury of ankle and foot
0.621 0.379 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.621 0.379 0.000
S95 Injury of blood vessels at ankle and foot level
0.621 0.379 0.000
S94 Injury of nerves at ankle and foot level
0.621 0.379 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.621 0.379 0.000
I72.4 Aneurysm of artery of lower extremity
0.621 0.379 0.000
B44 Aspergillosis
0.621 0.379 0.000
Q07 Other congenital malformations of nervous system
0.620 0.380 0.000
G93.7 Reye's syndrome
0.620 0.380 0.000
G93.5 Compression of brain
0.620 0.380 0.000
J30-J39 Other diseases of upper respiratory tract
0.620 0.380 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.619 0.381 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.619 0.381 0.000
H33 Retinal detachments and breaks
0.619 0.381 0.000
Q76 Congenital malformations of spine and bony thorax
0.618 0.382 0.000
Y57.5 X-ray contrast media
0.618 0.382 0.000
G52 Disorders of other cranial nerves
0.617 0.383 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.617 0.383 0.000
B01 Varicella [chickenpox]
0.616 0.383 0.000
S32.01 Fracture of lumbar vertebra (open)
0.616 0.384 0.000
E03.9 Hypothyroidism, unspecified
0.615 0.385 0.000
Q37 Cleft palate with cleft lip
0.615 0.385 0.000
Q05 Spina bifida
0.614 0.386 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.614 0.386 0.000
G57.4 Lesion of medial popliteal nerve
0.614 0.386 0.000
G57.2 Lesion of femoral nerve
0.614 0.386 0.000
G57.0 Lesion of sciatic nerve
0.614 0.386 0.000
E87.5 Hyperkalaemia
0.614 0.386 0.000
T25 Burn and corrosion of ankle and foot
0.614 0.386 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.614 0.386 0.000
T20 Burn and corrosion of head and neck
0.614 0.386 0.000
H20.1 Chronic iridocyclitis
0.613 0.386 0.000
R63 Symptoms and signs concerning food and fluid intake
0.613 0.387 0.000
I00-I02 Acute rheumatic fever
0.613 0.387 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.613 0.387 0.000
E00 Congenital iodine-deficiency syndrome
0.613 0.387 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.613 0.387 0.000
G81 Hemiplegia
0.613 0.387 0.000
Y52.1 Calcium-channel blockers
0.612 0.387 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.612 0.388 0.000
H20.8 Other iridocyclitis
0.612 0.388 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.611 0.389 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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