TreeWAS – Variant ID: rs658191

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.214	0.786
M06.9 Rheumatoid arthritis, unspecified	0.203	0.797
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.192	0.808
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.173	0.827
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.164	0.835
M06 Other rheumatoid arthritis	0.153	0.847
M06.98 Rheumatoid arthritis, unspecified (Other)	0.146	0.854
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.146	0.854
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.146	0.854
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.146	0.854
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.131	0.869
M06.4 Inflammatory polyarthropathy	0.122	0.878
M06.8 Other specified rheumatoid arthritis	0.110	0.890
M06.3 Rheumatoid nodule	0.110	0.890
M06.2 Rheumatoid bursitis	0.110	0.890
M06.1 Adult-onset Still's disease	0.110	0.890
M06.0 Seronegative rheumatoid arthritis	0.107	0.893
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.107	0.893
M05-M14 Inflammatory polyarthropathies	0.105	0.895
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.100	0.900
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.088	0.912
M06.48 Inflammatory polyarthropathy (Other)	0.088	0.912
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.088	0.912
M06.46 Inflammatory polyarthropathy (Lower leg)	0.088	0.912
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.088	0.912
M06.44 Inflammatory polyarthropathy (Hand)	0.088	0.912
M06.43 Inflammatory polyarthropathy (Forearm)	0.088	0.912
M06.42 Inflammatory polyarthropathy (Upper arm)	0.088	0.912
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.088	0.912
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.088	0.912
M20-M25 Other joint disorders	0.085	0.915
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.083	0.916
M65-M68 Disorders of synovium and tendon	0.080	0.920
M06.19 Adult-onset Still's disease (Site unspecified)	0.079	0.921
M06.18 Adult-onset Still's disease (Other)	0.079	0.921
M06.17 Adult-onset Still's disease (Ankle and foot)	0.079	0.921
M06.16 Adult-onset Still's disease (Lower leg)	0.079	0.921
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.079	0.921
M06.14 Adult-onset Still's disease (Hand)	0.079	0.921
M06.13 Adult-onset Still's disease (Forearm)	0.079	0.921
M06.12 Adult-onset Still's disease (Upper arm)	0.079	0.921
M06.11 Adult-onset Still's disease (Shoulder region)	0.079	0.921
M06.10 Adult-onset Still's disease (Multiple sites)	0.079	0.921
M06.29 Rheumatoid bursitis (Site unspecified)	0.079	0.921
M06.28 Rheumatoid bursitis (Other)	0.079	0.921
M06.27 Rheumatoid bursitis (Ankle and foot)	0.079	0.921
M06.26 Rheumatoid bursitis (Lower leg)	0.079	0.921
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.079	0.921
M06.24 Rheumatoid bursitis (Hand)	0.079	0.921
M06.23 Rheumatoid bursitis (Forearm)	0.079	0.921
M06.22 Rheumatoid bursitis (Upper arm)	0.079	0.921
M06.21 Rheumatoid bursitis (Shoulder region)	0.079	0.921
M06.20 Rheumatoid bursitis (Multiple sites)	0.079	0.921
M06.39 Rheumatoid nodule (Site unspecified)	0.079	0.921
M06.38 Rheumatoid nodule (Other)	0.079	0.921
M06.37 Rheumatoid nodule (Ankle and foot)	0.079	0.921
M06.36 Rheumatoid nodule (Lower leg)	0.079	0.921
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.079	0.921
M06.34 Rheumatoid nodule (Hand)	0.079	0.921
M06.33 Rheumatoid nodule (Forearm)	0.079	0.921
M06.32 Rheumatoid nodule (Upper arm)	0.079	0.921
M06.31 Rheumatoid nodule (Shoulder region)	0.079	0.921
M06.30 Rheumatoid nodule (Multiple sites)	0.079	0.921
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.079	0.921
M06.88 Other specified rheumatoid arthritis (Other)	0.079	0.921
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.079	0.921
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.079	0.921
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.079	0.921
M06.84 Other specified rheumatoid arthritis (Hand)	0.079	0.921
M06.83 Other specified rheumatoid arthritis (Forearm)	0.079	0.921
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.079	0.921
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.079	0.921
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.079	0.921
M35 Other systemic involvement of connective tissue	0.079	0.921
M06.08 Seronegative rheumatoid arthritis (Other)	0.077	0.923
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.077	0.923
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.077	0.923
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.077	0.923
M06.04 Seronegative rheumatoid arthritis (Hand)	0.077	0.923
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.077	0.923
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.077	0.923
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.077	0.923
M07 Psoriatic and enteropathic arthropathies	0.076	0.924
M14 Arthropathies in other diseases classified elsewhere	0.076	0.924
M12 Other specific arthropathies	0.076	0.924
M09 Juvenile arthritis in diseases classified elsewhere	0.076	0.924
M08 Juvenile arthritis	0.076	0.924
M60-M63 Disorders of muscles	0.076	0.924
M05 Seropositive rheumatoid arthritis	0.075	0.924
M24 Other specific joint derangements	0.075	0.925
M10 Gout	0.075	0.925
M35.3 Polymyalgia rheumatica	0.074	0.926
M11 Other crystal arthropathies	0.073	0.926
M80-M85 Disorders of bone density and structure	0.073	0.927
M22 Disorders of patella	0.072	0.928
M34 Systemic sclerosis	0.071	0.929
M65 Synovitis and tenosynovitis	0.070	0.930
M21 Other acquired deformities of limbs	0.070	0.930
M86-M90 Other osteopathies	0.069	0.931
M25 Other joint disorders, not elsewhere classified	0.068	0.932
M62 Other disorders of muscle	0.067	0.933
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.066	0.934
M91-M94 Chondropathies	0.065	0.935
M35.1 Other overlap syndromes	0.065	0.935
M35.7 Hypermobility syndrome	0.064	0.936
M65.3 Trigger finger	0.064	0.936
M84 Disorders of continuity of bone	0.064	0.936
M67 Other disorders of synovium and tendon	0.063	0.937
M00-M03 Infectious arthropathies	0.063	0.937
M34.1 CR(E)ST syndrome	0.063	0.937
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.062	0.938
M40-M43 Deforming dorsopathies	0.062	0.938
M24.5 Contracture of joint	0.061	0.939
M66 Spontaneous rupture of synovium and tendon	0.061	0.939
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.061	0.939
M33 Dermatopolymyositis	0.061	0.939
M32 Systemic lupus erythematosus	0.061	0.939
M30 Polyarteritis nodosa and related conditions	0.061	0.939
M22.4 Chondromalacia patellae	0.061	0.939
M62.8 Other specified disorders of muscle	0.061	0.939
M65.34 Trigger finger-Hand	0.059	0.941
M24.8 Other specific joint derangements, not elsewhere classified	0.059	0.941
M24.2 Disorder of ligament	0.059	0.941
M25.3 Other instability of joint	0.059	0.941
M88 Paget's disease of bone [osteitis deformans]	0.058	0.942
M24.1 Other articular cartilage disorders	0.058	0.942
M84.1 Nonunion of fracture [pseudarthrosis]	0.058	0.942
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.057	0.942
M21.3 Wrist or foot drop (acquired)	0.057	0.942
M31 Other necrotising vasculopathies	0.057	0.943
M65.4 Radial styloid tenosynovitis [de Quervain]	0.057	0.943
M22.3 Other derangements of patella	0.057	0.943
M35.9 Systemic involvement of connective tissue, unspecified	0.056	0.943
M35.8 Other specified systemic involvement of connective tissue	0.056	0.943
M35.6 Relapsing panniculitis [Weber-Christian]	0.056	0.943
M35.5 Multifocal fibrosclerosis	0.056	0.943
M35.4 Diffuse (eosinophilic) fasciitis	0.056	0.943
M35.2 Behcet's disease	0.056	0.943
M80 Osteoporosis with pathological fracture	0.056	0.944
M45-M49 Spondylopathies	0.056	0.944
M25.8 Other specified joint disorders	0.056	0.944
M21.4 Flat foot [pes planus] (acquired)	0.055	0.945
M24.0 Loose body in joint	0.055	0.945
M07.3 Other psoriatic arthropathies	0.055	0.945
M22.8 Other disorders of patella	0.055	0.945
M07.6 Other enteropathic arthropathies	0.055	0.945
M07.5 Arthropathy in ulcerative colitis	0.055	0.945
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.055	0.945
M07.2 Psoriatic spondylitis	0.055	0.945
M07.1 Arthritis mutilans	0.055	0.945
M07.0 Distal interphalangeal psoriatic arthropathy	0.055	0.945
M24.4 Recurrent dislocation and subluxation of joint	0.055	0.945
M08.9 Juvenile arthritis, unspecified	0.054	0.945
M08.8 Other juvenile arthritis	0.054	0.945
M08.4 Pauciarticular juvenile arthritis	0.054	0.945
M08.3 Juvenile polyarthritis (seronegative)	0.054	0.945
M08.2 Juvenile arthritis with systemic onset	0.054	0.945
M08.1 Juvenile ankylosing spondylitis	0.054	0.945
M08.0 Juvenile rheumatoid arthritis	0.054	0.945
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.054	0.945
M09.2 Juvenile arthritis in ulcerative colitis	0.054	0.945
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.054	0.945
M09.0 Juvenile arthritis in psoriasis	0.054	0.945
M12.8 Other specific arthropathies, not elsewhere classified	0.054	0.945
M12.5 Traumatic arthropathy	0.054	0.945
M12.4 Intermittent hydrarthrosis	0.054	0.945
M12.3 Palindromic rheumatism	0.054	0.945
M12.2 Villonodular synovitis (pigmented)	0.054	0.945
M12.1 Kaschin-Beck disease	0.054	0.945
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.054	0.945
M14.8 Arthropathies in other specified diseases classified elsewhere	0.054	0.945
M14.6 Neuropathic arthropathy	0.054	0.945
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.054	0.945
M14.4 Arthropathy in amyloidosis	0.054	0.945
M14.3 Lipoid dermatoarthritis	0.054	0.945
M14.2 Diabetic arthropathy	0.054	0.945
M14.1 Crystal arthropathy in other metabolic disorders	0.054	0.945
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.054	0.945
M63 Disorders of muscle in diseases classified elsewhere	0.054	0.945
M61 Calcification and ossification of muscle	0.054	0.945
M60 Myositis	0.054	0.945
M05.8 Other seropositive rheumatoid arthritis	0.054	0.946
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.054	0.946
M05.2 Rheumatoid vasculitis	0.054	0.946
M05.1 Rheumatoid lung disease	0.054	0.946
M05.0 Felty's syndrome	0.054	0.946
M24.9 Joint derangement, unspecified	0.054	0.946
M24.7 Protrusio acetabuli	0.054	0.946
M24.6 Ankylosis of joint	0.054	0.946
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.054	0.946
M05.9 Seropositive rheumatoid arthritis, unspecified	0.054	0.946
M85 Other disorders of bone density and structure	0.054	0.946
M10.4 Other secondary gout	0.054	0.946
M10.3 Gout due to impairment of renal function	0.054	0.946
M10.2 Drug-induced gout	0.054	0.946
M10.1 Lead-induced gout	0.054	0.946
M10.0 Idiopathic gout	0.054	0.946
M25.0 Haemarthrosis	0.053	0.947
M11.9 Crystal arthropathy, unspecified	0.053	0.947
M11.8 Other specified crystal arthropathies	0.053	0.947
M11.1 Familial chondrocalcinosis	0.053	0.947
M11.0 Hydroxyapatite deposition disease	0.053	0.947
M13 Other arthritis	0.053	0.947
M10.9 Gout, unspecified	0.053	0.947
M25.6 Stiffness of joint, not elsewhere classified	0.052	0.948
M83 Adult osteomalacia	0.052	0.948
M82 Osteoporosis in diseases classified elsewhere	0.052	0.948
M25.9 Joint disorder, unspecified	0.052	0.948
M62.88 Other specified disorders of muscle (Other)	0.052	0.948
M22.1 Recurrent subluxation of patella	0.052	0.948
M22.9 Disorder of patella, unspecified	0.052	0.948
M22.0 Recurrent dislocation of patella	0.052	0.948
M24.54 Contracture of joint (Hand)	0.051	0.949
M50-M54 Other dorsopathies	0.051	0.949
M34.8 Other forms of systemic sclerosis	0.051	0.949
M34.2 Systemic sclerosis induced by drugs and chemicals	0.051	0.949
M34.0 Progressive systemic sclerosis	0.051	0.949
M11.2 Other chondrocalcinosis	0.051	0.949
M65.8 Other synovitis and tenosynovitis	0.051	0.949
M65.2 Calcific tendinitis	0.051	0.949
M65.1 Other infective (teno)synovitis	0.051	0.949
M65.0 Abscess of tendon sheath	0.051	0.949
M21.0 Valgus deformity, not elsewhere classified	0.050	0.949
M21.9 Acquired deformity of limb, unspecified	0.050	0.949
M21.8 Other specified acquired deformities of limbs	0.050	0.949
M21.7 Unequal limb length (acquired)	0.050	0.949
M21.6 Other acquired deformities of ankle and foot	0.050	0.949
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.050	0.949
M21.2 Flexion deformity	0.050	0.949
M94 Other disorders of cartilage	0.050	0.950
M67.8 Other specified disorders of synovium and tendon	0.050	0.950
M90 Osteopathies in diseases classified elsewhere	0.050	0.950
M88.9 Paget's disease of bone, unspecified	0.050	0.950
M87 Osteonecrosis	0.050	0.950
M62.81 Other specified disorders of muscle (Shoulder region)	0.050	0.950
M25.4 Effusion of joint	0.050	0.950
M25.2 Flail joint	0.049	0.951
M25.1 Fistula of joint	0.049	0.951
M21.1 Varus deformity, not elsewhere classified	0.049	0.951
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.048	0.952
M25.31 Other instability of joint (Shoulder region)	0.048	0.952
M62.9 Disorder of muscle, unspecified	0.048	0.952
M62.6 Muscle strain	0.048	0.952
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.048	0.952
M62.4 Contracture of muscle	0.048	0.952
M62.3 Immobility syndrome (paraplegic)	0.048	0.952
M62.2 Ischaemic infarction of muscle	0.048	0.952
M62.1 Other rupture of muscle (nontraumatic)	0.048	0.952
M62.0 Diastasis of muscle	0.048	0.952
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.048	0.952
M89 Other disorders of bone	0.048	0.952
M66.2 Spontaneous rupture of extensor tendons	0.048	0.952
M86 Osteomyelitis	0.047	0.952
M67.2 Synovial hypertrophy, not elsewhere classified	0.047	0.952
M25.37 Other instability of joint (Ankle and foot)	0.047	0.952
M62.86 Other specified disorders of muscle (Lower leg)	0.047	0.952
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.047	0.952
M92 Other juvenile osteochondrosis	0.047	0.953
M91 Juvenile osteochondrosis of hip and pelvis	0.047	0.953
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.047	0.953
M24.27 Disorder of ligament (Ankle and foot)	0.047	0.953
M34.9 Systemic sclerosis, unspecified	0.046	0.953
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.046	0.954
M65.39 Trigger finger-Site unspec	0.046	0.954
M65.38 Trigger finger-Other	0.046	0.954
M65.37 Trigger finger-Ankle/foot	0.046	0.954
M65.36 Trigger finger-Lower leg	0.046	0.954
M65.35 Trigger finger-Pelvic/thigh	0.046	0.954
M65.33 Trigger finger-Forearm	0.046	0.954
M65.32 Trigger finger-Upper arm	0.046	0.954
M65.31 Trigger finger-Shldr region	0.046	0.954
M65.30 Trigger finger-Mult sites	0.046	0.954
M84.9 Disorder of continuity of bone, unspecified	0.046	0.954
M84.8 Other disorders of continuity of bone	0.046	0.954
M84.4 Pathological fracture, not elsewhere classified	0.046	0.954
M84.3 Stress fracture, not elsewhere classified	0.046	0.954
M84.2 Delayed union of fracture	0.046	0.954
M67.9 Disorder of synovium and tendon, unspecified	0.046	0.954
M67.4 Ganglion	0.046	0.954
M67.3 Transient synovitis	0.046	0.954
M67.1 Other contracture of tendon (sheath)	0.046	0.954
M67.0 Short Achilles tendon (acquired)	0.046	0.954
M93 Other osteochondropathies	0.045	0.954
M22.2 Patellofemoral disorders	0.045	0.954
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.045	0.954
M02 Reactive arthropathies	0.045	0.954
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.045	0.954
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.045	0.955
M25.86 Other specified joint disorders (Lower leg)	0.045	0.955
M00 Pyogenic arthritis	0.045	0.955
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.045	0.955
M84.0 Malunion of fracture	0.045	0.955
M99 Biomechanical lesions, not elsewhere classified	0.045	0.955
M80.0 Postmenopausal osteoporosis with pathological fracture	0.045	0.955
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.044	0.955
M42 Spinal osteochondrosis	0.044	0.955
M40 Kyphosis and lordosis	0.044	0.955
M41 Scoliosis	0.044	0.956
M24.59 Contracture of joint (Site unspecified)	0.044	0.956
M24.58 Contracture of joint (Other)	0.044	0.956
M24.57 Contracture of joint (Ankle and foot)	0.044	0.956
M24.56 Contracture of joint (Lower leg)	0.044	0.956
M24.55 Contracture of joint (Pelvic region and thigh)	0.044	0.956
M24.53 Contracture of joint (Forearm)	0.044	0.956
M24.52 Contracture of joint (Upper arm)	0.044	0.956
M24.51 Contracture of joint (Shoulder region)	0.044	0.956
M24.50 Contracture of joint (Multiple sites)	0.044	0.956
M24.17 Other articular cartilage disorders (Ankle and foot)	0.044	0.956
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.044	0.956
M66.5 Spontaneous rupture of unspecified tendon	0.044	0.956
M66.4 Spontaneous rupture of other tendons	0.044	0.956
M66.3 Spontaneous rupture of flexor tendons	0.044	0.956
M66.1 Rupture of synovium	0.044	0.956
M66.0 Rupture of popliteal cyst	0.044	0.956
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.044	0.956
M30.8 Other conditions related to polyarteritis nodosa	0.044	0.956
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.044	0.956
M30.2 Juvenile polyarteritis	0.044	0.956
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.044	0.956
M30.0 Polyarteritis nodosa	0.044	0.956
M32.9 Systemic lupus erythematosus, unspecified	0.044	0.956
M32.8 Other forms of systemic lupus erythematosus	0.044	0.956
M32.1 Systemic lupus erythematosus with organ or system involvement	0.044	0.956
M32.0 Drug-induced systemic lupus erythematosus	0.044	0.956
M33.9 Dermatopolymyositis, unspecified	0.044	0.956
M33.2 Polymyositis	0.044	0.956
M33.1 Other dermatomyositis	0.044	0.956
M33.0 Juvenile dermatomyositis	0.044	0.956
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.044	0.956
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.044	0.956
M36.3 Arthropathy in other blood disorders	0.044	0.956
M36.2 Haemophilic arthropathy	0.044	0.956
M36.1 Arthropathy in neoplastic disease	0.044	0.956
M36.0 Dermato(poly)myositis in neoplastic disease	0.044	0.956
M07.30 Other psoriatic arthropathies (Multiple sites)	0.044	0.956
M62.89 Other specified disorders of muscle (Site unspecified)	0.044	0.956
M62.87 Other specified disorders of muscle (Ankle and foot)	0.044	0.956
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.044	0.956
M62.84 Other specified disorders of muscle (Hand)	0.044	0.956
M62.83 Other specified disorders of muscle (Forearm)	0.044	0.956
M62.82 Other specified disorders of muscle (Upper arm)	0.044	0.956
M62.80 Other specified disorders of muscle (Multiple sites)	0.044	0.956
M43 Other deforming dorsopathies	0.043	0.957
M25.84 Other specified joint disorders (Hand)	0.043	0.957
M25.06 Haemarthrosis (Lower leg)	0.043	0.957
M24.16 Other articular cartilage disorders (Lower leg)	0.042	0.958
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.042	0.958
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.042	0.958
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.042	0.958
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.042	0.958
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.042	0.958
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.042	0.958
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.042	0.958
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.042	0.958
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.042	0.958
M24.29 Disorder of ligament (Site unspecified)	0.042	0.958
M24.28 Disorder of ligament (Other)	0.042	0.958
M24.26 Disorder of ligament (Lower leg)	0.042	0.958
M24.25 Disorder of ligament (Pelvic region and thigh)	0.042	0.958
M24.24 Disorder of ligament (Hand)	0.042	0.958
M24.23 Disorder of ligament (Forearm)	0.042	0.958
M24.22 Disorder of ligament (Upper arm)	0.042	0.958
M24.21 Disorder of ligament (Shoulder region)	0.042	0.958
M24.20 Disorder of ligament (Multiple sites)	0.042	0.958
M25.39 Other instability of joint (Site unspecified)	0.042	0.958
M25.38 Other instability of joint (Other)	0.042	0.958
M25.36 Other instability of joint (Lower leg)	0.042	0.958
M25.35 Other instability of joint (Pelvic region and thigh)	0.042	0.958
M25.34 Other instability of joint (Hand)	0.042	0.958
M25.33 Other instability of joint (Forearm)	0.042	0.958
M25.32 Other instability of joint (Upper arm)	0.042	0.958
M25.30 Other instability of joint (Multiple sites)	0.042	0.958
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.042	0.958
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.042	0.958
M88.8 Paget's disease of other bones	0.041	0.958
M88.0 Paget's disease of skull	0.041	0.958
M24.19 Other articular cartilage disorders (Site unspecified)	0.041	0.958
M24.18 Other articular cartilage disorders (Other)	0.041	0.958
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.041	0.958
M24.14 Other articular cartilage disorders (Hand)	0.041	0.958
M24.13 Other articular cartilage disorders (Forearm)	0.041	0.958
M24.12 Other articular cartilage disorders (Upper arm)	0.041	0.958
M24.11 Other articular cartilage disorders (Shoulder region)	0.041	0.958
M24.10 Other articular cartilage disorders (Multiple sites)	0.041	0.958
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.041	0.958
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.041	0.958
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.041	0.958
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.041	0.958
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.041	0.958
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.041	0.958
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.041	0.958
M21.39 Wrist or foot drop (acquired)-Site unspec	0.041	0.958
M21.38 Wrist or foot drop (acquired)-Other	0.041	0.958
M21.36 Wrist or foot drop (acquired)-Lower leg	0.041	0.958
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.041	0.958
M21.34 Wrist or foot drop (acquired) (Hand)	0.041	0.958
M21.33 Wrist or foot drop (acquired) (Forearm)	0.041	0.958
M21.32 Wrist or foot drop (acquired)-Upper arm	0.041	0.958
M21.31 Wrist or foot drop (acquired)-Shldr region	0.041	0.958
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.041	0.958
M31.9 Necrotising vasculopathy, unspecified	0.041	0.959
M31.8 Other specified necrotising vasculopathies	0.041	0.959
M31.7 Microscopic polyangiitis	0.041	0.959
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.041	0.959
M31.4 Aortic arch syndrome [Takayasu]	0.041	0.959
M31.2 Lethal midline granuloma	0.041	0.959
M31.1 Thrombotic microangiopathy	0.041	0.959
M31.0 Hypersensitivity angiitis	0.041	0.959
M54 Dorsalgia	0.041	0.959
M10.96 Gout, unspecified (Lower leg)	0.041	0.959
M45 Ankylosing spondylitis	0.041	0.959
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.041	0.959
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.041	0.959
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.041	0.959
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.041	0.959
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.041	0.959
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.041	0.959
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.041	0.959
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.041	0.959
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.041	0.959
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.041	0.959
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.041	0.959
M80.9 Unspecified osteoporosis with pathological fracture	0.041	0.959
M65.9 Synovitis and tenosynovitis, unspecified	0.041	0.959
M80.8 Other osteoporosis with pathological fracture	0.041	0.959
M80.5 Idiopathic osteoporosis with pathological fracture	0.041	0.959
M80.4 Drug-induced osteoporosis with pathological fracture	0.041	0.959
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.041	0.959
M80.2 Osteoporosis of disuse with pathological fracture	0.041	0.959
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.041	0.959
M25.96 Joint disorder, unspecified (Lower leg)	0.041	0.959
M25.45 Effusion of joint (Pelvic region and thigh)	0.041	0.959
M24.07 Loose body in joint (Ankle and foot)	0.040	0.959
M49 Spondylopathies in diseases classified elsewhere	0.040	0.959
M25.89 Other specified joint disorders (Site unspecified)	0.040	0.960
M25.88 Other specified joint disorders (Other)	0.040	0.960
M25.87 Other specified joint disorders (Ankle and foot)	0.040	0.960
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.040	0.960
M25.83 Other specified joint disorders (Forearm)	0.040	0.960
M25.82 Other specified joint disorders (Upper arm)	0.040	0.960
M25.81 Other specified joint disorders (Shoulder region)	0.040	0.960
M25.80 Other specified joint disorders (Multiple sites)	0.040	0.960
M85.8 Other specified disorders of bone density and structure	0.040	0.960
M31.6 Other giant cell arteritis	0.040	0.960
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.040	0.960
M81 Osteoporosis without pathological fracture	0.040	0.960
M47 Spondylosis	0.040	0.960
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.040	0.960
M21.48 Flat foot [pes planus] (acquired)-Other	0.040	0.960
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.040	0.960
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.040	0.960
M21.44 Flat foot [pes planus] (acquired)-Hand	0.040	0.960
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.040	0.960
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.040	0.960
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.040	0.960
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.040	0.960
M24.09 Loose body in joint (Site unspecified)	0.040	0.960
M24.08 Loose body in joint (Other)	0.040	0.960
M24.06 Loose body in joint-Lower leg	0.040	0.960
M24.05 Loose body in joint (Pelvic region and thigh)	0.040	0.960
M24.04 Loose body in joint (Hand)	0.040	0.960
M24.03 Loose body in joint (Forearm)	0.040	0.960
M24.02 Loose body in joint (Upper arm)	0.040	0.960
M24.01 Loose body in joint (Shoulder region)	0.040	0.960
M24.00 Loose body in joint (Multiple sites)	0.040	0.960
M94.8 Other specified disorders of cartilage	0.040	0.960
M07.38 Other psoriatic arthropathies (Other)	0.039	0.960
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.039	0.960
M07.36 Other psoriatic arthropathies (Lower leg)	0.039	0.960
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.039	0.960
M07.34 Other psoriatic arthropathies (Hand)	0.039	0.960
M07.33 Other psoriatic arthropathies (Forearm)	0.039	0.960
M07.32 Other psoriatic arthropathies (Upper arm)	0.039	0.960
M07.31 Other psoriatic arthropathies (Shoulder region)	0.039	0.960
M85.0 Fibrous dysplasia (monostotic)	0.039	0.960
M70-M79 Other soft tissue disorders	0.040	0.960
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.039	0.960
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.039	0.960
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.039	0.960
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.039	0.960
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.039	0.960
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.039	0.960
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.039	0.960
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.039	0.960
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.039	0.960
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.039	0.960
M07.19 Arthritis mutilans (Site unspecified)	0.039	0.960
M07.18 Arthritis mutilans (Other)	0.039	0.960
M07.17 Arthritis mutilans (Ankle and foot)	0.039	0.960
M07.16 Arthritis mutilans (Lower leg)	0.039	0.960
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.039	0.960
M07.14 Arthritis mutilans (Hand)	0.039	0.960
M07.13 Arthritis mutilans (Forearm)	0.039	0.960
M07.12 Arthritis mutilans (Upper arm)	0.039	0.960
M07.11 Arthritis mutilans (Shoulder region)	0.039	0.960
M07.10 Arthritis mutilans (Multiple sites)	0.039	0.960
M07.29 Psoriatic spondylitis (Site unspecified)	0.039	0.960
M07.28 Psoriatic spondylitis (Other)	0.039	0.960
M07.27 Psoriatic spondylitis (Ankle and foot)	0.039	0.960
M07.26 Psoriatic spondylitis (Lower leg)	0.039	0.960

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations