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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs664172
log Bayes Factor = 16.0595
Chromosome 15   position 78,862,762  (GRCh37) Explore rs664172 on Ensembl!
Variant rs664172 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.001 0.999
I71 Aortic aneurysm and dissection
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.002 0.998
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.008 0.992
I70 Atherosclerosis
0.000 0.012 0.988
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.019 0.981
I73.9 Peripheral vascular disease, unspecified
0.000 0.021 0.979
J42 Unspecified chronic bronchitis
0.000 0.024 0.976
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.026 0.974
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.033 0.967
I72 Other aneurysm
0.000 0.090 0.910
I73.0 Raynaud's syndrome
0.000 0.101 0.899
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.115 0.885
I77 Other disorders of arteries and arterioles
0.000 0.123 0.877
I72.8 Aneurysm of other specified arteries
0.000 0.180 0.820
J43.2 Centrilobular emphysema
0.000 0.203 0.797
Chapter X Diseases of the respiratory system
0.000 0.205 0.795
I70.0 Atherosclerosis of aorta
0.000 0.221 0.779
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.224 0.776
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.227 0.773
J90-J94 Other diseases of pleura
0.000 0.228 0.772
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.232 0.768
J92 Pleural plaque
0.000 0.237 0.763
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.240 0.759
I72.0 Aneurysm of carotid artery
0.000 0.242 0.758
J95-J99 Other diseases of the respiratory system
0.000 0.245 0.755
J60-J70 Lung diseases due to external agents
0.000 0.254 0.746
J92.0 Pleural plaque with presence of asbestos
0.000 0.264 0.736
I71.0 Dissection of aorta [any part]
0.000 0.267 0.733
I77.1 Stricture of artery
0.000 0.267 0.733
I77.0 Arteriovenous fistula, acquired
0.000 0.272 0.728
I72.9 Aneurysm of unspecified site
0.000 0.273 0.727
J98 Other respiratory disorders
0.000 0.279 0.721
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.280 0.720
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.281 0.719
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.284 0.716
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.284 0.716
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.284 0.716
I78 Diseases of capillaries
0.000 0.288 0.712
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.289 0.711
J92.9 Pleural plaque without asbestos
0.000 0.291 0.709
I70.9 Generalised and unspecified atherosclerosis
0.000 0.292 0.708
I70.8 Atherosclerosis of other arteries
0.000 0.292 0.708
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.305 0.695
I77.2 Rupture of artery
0.000 0.310 0.690
J98.1 Pulmonary collapse
0.000 0.313 0.687
J86 Pyothorax
0.000 0.323 0.677
J98.4 Other disorders of lung
0.000 0.324 0.676
J90 Pleural effusion, not elsewhere classified
0.000 0.324 0.676
I72.3 Aneurysm of iliac artery
0.000 0.339 0.661
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.347 0.653
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.347 0.653
I72.1 Aneurysm of artery of upper extremity
0.000 0.347 0.653
J86.9 Pyothorax without fistula
0.000 0.348 0.652
J43.8 Other emphysema
0.000 0.356 0.643
I74 Arterial embolism and thrombosis
0.000 0.360 0.640
I73.8 Other specified peripheral vascular diseases
0.000 0.366 0.634
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.371 0.629
I77.5 Necrosis of artery
0.000 0.371 0.628
I77.4 Coeliac artery compression syndrome
0.000 0.371 0.628
J98.9 Respiratory disorder, unspecified
0.000 0.376 0.624
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.384 0.616
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.400 0.600
J60 Coalworker's pneumoconiosis
0.000 0.407 0.593
J40 Bronchitis, not specified as acute or chronic
0.000 0.415 0.585
I72.4 Aneurysm of artery of lower extremity
0.000 0.418 0.582
I70.1 Atherosclerosis of renal artery
0.000 0.420 0.580
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.428 0.572
J69 Pneumonitis due to solids and liquids
0.000 0.434 0.566
I72.2 Aneurysm of renal artery
0.000 0.436 0.563
J64 Unspecified pneumoconiosis
0.000 0.439 0.561
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.441 0.558
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.444 0.556
I79.1 Aortitis in diseases classified elsewhere
0.000 0.444 0.556
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.444 0.556
J98.2 Interstitial emphysema
0.000 0.449 0.551
J96 Respiratory failure, not elsewhere classified
0.000 0.458 0.541
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.465 0.535
J66 Airway disease due to specific organic dust
0.000 0.465 0.535
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.465 0.535
J62 Pneumoconiosis due to dust containing silica
0.000 0.465 0.535
J65 Pneumoconiosis associated with tuberculosis
0.000 0.465 0.535
I77.8 Other specified disorders of arteries and arterioles
0.000 0.477 0.523
I77.3 Arterial fibromuscular dysplasia
0.000 0.481 0.519
J98.3 Compensatory emphysema
0.000 0.483 0.517
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I78.9 Disease of capillaries, unspecified
0.000 0.490 0.510
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.490 0.510
J70 Respiratory conditions due to other external agents
0.000 0.490 0.509
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.492 0.508
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.492 0.508
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.492 0.508
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.492 0.508
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.493 0.507
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.497 0.502
J46 Status asthmaticus
0.000 0.499 0.501
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.500 0.500
I78.8 Other diseases of capillaries
0.000 0.504 0.496
I77.6 Arteritis, unspecified
0.000 0.514 0.486
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.518 0.482
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.525 0.475
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.527 0.473
J93 Pneumothorax
0.000 0.530 0.470
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.541 0.459
J85 Abscess of lung and mediastinum
0.000 0.543 0.457
I74.5 Embolism and thrombosis of iliac artery
0.000 0.549 0.451
J99.0 Rheumatoid lung disease
0.000 0.551 0.449
J86.0 Pyothorax with fistula
0.000 0.551 0.448
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.558 0.442
J69.8 Pneumonitis due to other solids and liquids
0.000 0.559 0.441
I78.1 Naevus, nonneoplastic
0.000 0.566 0.434
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.568 0.432
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.584 0.416
J93.1 Other spontaneous pneumothorax
0.000 0.592 0.408
J69.1 Pneumonitis due to oils and essences
0.000 0.594 0.406
J91 Pleural effusion in conditions classified elsewhere
0.000 0.595 0.405
J69.0 Pneumonitis due to food and vomit
0.000 0.599 0.401
J98.6 Disorders of diaphragm
0.000 0.602 0.398
J95.8 Other postprocedural respiratory disorders
0.000 0.610 0.390
J94 Other pleural conditions
0.000 0.611 0.389
J96.9 Respiratory failure, unspecified
0.000 0.612 0.388
J96.1 Chronic respiratory failure
0.000 0.612 0.388
J96.0 Acute respiratory failure
0.000 0.612 0.388
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.612 0.388
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.616 0.383
J62.0 Pneumoconiosis due to talc dust
0.000 0.616 0.383
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.616 0.383
J63.5 Stannosis
0.000 0.616 0.383
J63.4 Siderosis
0.000 0.616 0.383
J63.3 Graphite fibrosis (of lung)
0.000 0.616 0.383
J63.2 Berylliosis
0.000 0.616 0.383
J63.1 Bauxite fibrosis (of lung)
0.000 0.616 0.383
J63.0 Aluminosis (of lung)
0.000 0.616 0.383
J66.8 Airway disease due to other specific organic dusts
0.000 0.616 0.383
J66.2 Cannabinosis
0.000 0.616 0.383
J66.1 Flax-dresser's disease
0.000 0.616 0.383
J66.0 Byssinosis
0.000 0.616 0.383
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.616 0.383
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.616 0.383
I74.8 Embolism and thrombosis of other arteries
0.000 0.618 0.382
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.624 0.376
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.635 0.365
J70.8 Respiratory conditions due to other specified external agents
0.000 0.635 0.365
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.635 0.365
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.635 0.365
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.635 0.365
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.635 0.365
J95.5 Postprocedural subglottic stenosis
0.000 0.636 0.364
J95.4 Mendelson's syndrome
0.000 0.636 0.364
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.636 0.364
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.636 0.364
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.636 0.364
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.640 0.360
J67.7 Air-conditioner and humidifier lung
0.000 0.640 0.360
J67.6 Maple-bark-stripper's lung
0.000 0.640 0.360
J67.5 Mushroom-worker's lung
0.000 0.640 0.360
J67.4 Maltworker's lung
0.000 0.640 0.360
J67.3 Suberosis
0.000 0.640 0.360
J67.1 Bagassosis
0.000 0.640 0.360
J67.0 Farmer's lung
0.000 0.640 0.360
J98.8 Other specified respiratory disorders
0.000 0.644 0.356
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.645 0.354
J95.0 Tracheostomy malfunction
0.000 0.655 0.345
J85.1 Abscess of lung with pneumonia
0.000 0.655 0.344
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.660 0.340
I60-I69 Cerebrovascular diseases
0.000 0.661 0.339
J67.2 Bird fancier's lung
0.000 0.665 0.335
I60 Subarachnoid haemorrhage
0.000 0.667 0.333
Chapter IX Diseases of the circulatory system
0.000 0.668 0.332
J85.3 Abscess of mediastinum
0.000 0.672 0.328
J85.0 Gangrene and necrosis of lung
0.000 0.672 0.328
I69 Sequelae of cerebrovascular disease
0.000 0.676 0.324
F17.1 Harmful use
0.000 0.680 0.320
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.682 0.318
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.685 0.314
J93.0 Spontaneous tension pneumothorax
0.000 0.687 0.313
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.691 0.309
I69.3 Sequelae of cerebral infarction
0.000 0.698 0.302
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.700 0.300
I67 Other cerebrovascular diseases
0.000 0.703 0.297
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.703 0.296
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.711 0.289
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.712 0.287
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.714 0.286
I60.8 Other subarachnoid haemorrhage
0.000 0.717 0.283
J94.8 Other specified pleural conditions
0.000 0.719 0.281
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.720 0.280
J94.9 Pleural condition, unspecified
0.000 0.721 0.279
J94.0 Chylous effusion
0.000 0.721 0.279
J96.09 Acute respiratory failure; Type unspecified
0.000 0.721 0.278
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.721 0.278
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.721 0.278
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.721 0.278
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.721 0.278
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.721 0.278
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.721 0.278
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.721 0.278
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.721 0.278
I26 Pulmonary embolism
0.000 0.723 0.277
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.725 0.275
J93.8 Other pneumothorax
0.000 0.726 0.274
I67.9 Cerebrovascular disease, unspecified
0.000 0.726 0.274
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.736 0.264
I27 Other pulmonary heart diseases
0.000 0.740 0.260
J20-J22 Other acute lower respiratory infections
0.000 0.741 0.259
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.743 0.257
I61 Intracerebral haemorrhage
0.000 0.747 0.253
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.748 0.252
J45 Asthma
0.000 0.748 0.252
I27.9 Pulmonary heart disease, unspecified
0.000 0.753 0.247
J09-J18 Influenza and pneumonia
0.000 0.753 0.247
J85.2 Abscess of lung without pneumonia
0.001 0.758 0.242
I67.1 Cerebral aneurysm, nonruptured
0.000 0.759 0.241
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.761 0.239
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.761 0.239
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.762 0.238
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.765 0.235
J94.1 Fibrothorax
0.000 0.765 0.235
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.765 0.235
I67.8 Other specified cerebrovascular diseases
0.000 0.766 0.234
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.767 0.233
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.768 0.232
I00-I02 Acute rheumatic fever
0.000 0.769 0.231
I28 Other diseases of pulmonary vessels
0.000 0.773 0.227
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.774 0.226
J00-J06 Acute upper respiratory infections
0.000 0.774 0.226
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.775 0.225
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.782 0.218
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.784 0.216
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.785 0.215
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.787 0.213
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.787 0.213
I67.5 Moyamoya disease
0.000 0.787 0.213
I67.4 Hypertensive encephalopathy
0.000 0.787 0.213
I67.3 Progressive vascular leukoencephalopathy
0.000 0.787 0.213
I27.8 Other specified pulmonary heart diseases
0.000 0.792 0.208
J93.9 Pneumothorax, unspecified
0.000 0.797 0.203
J84 Other interstitial pulmonary diseases
0.000 0.800 0.200
I68.0 Cerebral amyloid angiopathy
0.000 0.801 0.199
F17.2 Dependence syndrome
0.000 0.801 0.199
I62 Other nontraumatic intracranial haemorrhage
0.000 0.804 0.196
J94.2 Haemothorax
0.000 0.811 0.189
I27.1 Kyphoscoliotic heart disease
0.000 0.813 0.187
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.814 0.186
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.815 0.185
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.815 0.185
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.815 0.185
J45.8 Mixed asthma
0.000 0.819 0.180
J45.1 Nonallergic asthma
0.000 0.819 0.180
J18 Pneumonia, organism unspecified
0.000 0.819 0.181
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.823 0.177
J09 Influenza due to certain identified influenza virus
0.000 0.823 0.177
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.824 0.176
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.824 0.176
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.827 0.173
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.827 0.173
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.827 0.173
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.827 0.173
J00 Acute nasopharyngitis [common cold]
0.000 0.829 0.171
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.829 0.171
I05-I09 Chronic rheumatic heart diseases
0.000 0.830 0.170
J21 Acute bronchiolitis
0.000 0.830 0.169
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.831 0.169
J18.1 Lobar pneumonia, unspecified
0.000 0.832 0.168
I28.8 Other specified diseases of pulmonary vessels
0.000 0.832 0.168
J10 Influenza due to identified influenza virus
0.000 0.834 0.166
I02 Rheumatic chorea
0.000 0.834 0.166
I01 Rheumatic fever with heart involvement
0.000 0.834 0.166
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.835 0.165
J12 Viral pneumonia, not elsewhere classified
0.000 0.836 0.164
J20 Acute bronchitis
0.000 0.836 0.164
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.836 0.163
J17 Pneumonia in diseases classified elsewhere
0.000 0.837 0.163
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.837 0.162
I28.1 Aneurysm of pulmonary artery
0.000 0.837 0.162
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.837 0.162
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.838 0.162
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.838 0.162
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.838 0.162
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.838 0.162
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.838 0.162
J84.8 Other specified interstitial pulmonary diseases
0.000 0.840 0.160
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.840 0.159
I00 Rheumatic fever without mention of heart involvement
0.000 0.841 0.158
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.843 0.157
F17.9 Unspecified mental and behavioural disorder
0.000 0.843 0.157
F17.8 Other mental and behavioural disorders
0.000 0.843 0.157
F17.7 Residual and late-onset psychotic disorder
0.000 0.843 0.157
F17.6 Amnesic syndrome
0.000 0.843 0.157
F17.5 Psychotic disorder
0.000 0.843 0.157
F17.4 Withdrawal state with delirium
0.000 0.843 0.157
F17.3 Withdrawal state
0.000 0.843 0.157
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.844 0.156
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.847 0.153
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.847 0.153
J14 Pneumonia due to Haemophilus influenzae
0.000 0.852 0.148
F17.0 Acute intoxication
0.000 0.852 0.148
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.852 0.148
J84.0 Alveolar and parietoalveolar conditions
0.000 0.856 0.144
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.856 0.143
J04 Acute laryngitis and tracheitis
0.000 0.859 0.141
I27.0 Primary pulmonary hypertension
0.000 0.859 0.141
I09 Other rheumatic heart diseases
0.000 0.862 0.138
J01 Acute sinusitis
0.000 0.865 0.135
I61.8 Other intracerebral haemorrhage
0.000 0.865 0.135
I67.2 Cerebral atherosclerosis
0.000 0.866 0.134
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.867 0.133
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.869 0.131
J18.2 Hypostatic pneumonia, unspecified
0.000 0.870 0.130
J05.1 Acute epiglottitis
0.000 0.872 0.128
J02 Acute pharyngitis
0.000 0.872 0.128
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.873 0.127
J16.0 Chlamydial pneumonia
0.000 0.873 0.127
J18.9 Pneumonia, unspecified
0.000 0.875 0.125
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.878 0.122
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.878 0.122
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.878 0.122
I07 Rheumatic tricuspid valve diseases
0.000 0.879 0.121
J05.0 Acute obstructive laryngitis [croup]
0.000 0.879 0.121
I62.1 Nontraumatic extradural haemorrhage
0.000 0.879 0.121
I05 Rheumatic mitral valve diseases
0.000 0.879 0.121
J03 Acute tonsillitis
0.000 0.879 0.121
I06 Rheumatic aortic valve diseases
0.000 0.880 0.120
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.880 0.120
J15.8 Other bacterial pneumonia
0.000 0.880 0.120
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.881 0.119
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.881 0.119
I01.8 Other acute rheumatic heart disease
0.000 0.881 0.119
I01.2 Acute rheumatic myocarditis
0.000 0.881 0.119
I01.1 Acute rheumatic endocarditis
0.000 0.881 0.119
I01.0 Acute rheumatic pericarditis
0.000 0.881 0.119
I02.9 Rheumatic chorea without heart involvement
0.000 0.881 0.119
I02.0 Rheumatic chorea with heart involvement
0.000 0.881 0.119
J18.8 Other pneumonia, organism unspecified
0.000 0.881 0.119
J15.2 Pneumonia due to staphylococcus
0.000 0.881 0.119
J12.8 Other viral pneumonia
0.000 0.882 0.118
J12.3 Human metapneumovirus pneumonia
0.000 0.882 0.118
J12.2 Parainfluenza virus pneumonia
0.000 0.882 0.118
J12.1 Respiratory syncytial virus pneumonia
0.000 0.882 0.118
J12.0 Adenoviral pneumonia
0.000 0.882 0.118
J20.7 Acute bronchitis due to echovirus
0.000 0.882 0.118
J20.6 Acute bronchitis due to rhinovirus
0.000 0.882 0.118
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.882 0.118
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.882 0.118
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.882 0.118
J20.2 Acute bronchitis due to streptococcus
0.000 0.882 0.118
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.882 0.118
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.882 0.118
J11 Influenza, virus not identified
0.000 0.882 0.117
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.883 0.117
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.884 0.116
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.884 0.115
I09.9 Rheumatic heart disease, unspecified
0.000 0.885 0.115
J15.5 Pneumonia due to Escherichia coli
0.000 0.886 0.114
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.886 0.114
J20.8 Acute bronchitis due to other specified organisms
0.000 0.887 0.113
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.887 0.113
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.888 0.112
J15.3 Pneumonia due to streptococcus, group B
0.000 0.888 0.112
I99 Other and unspecified disorders of circulatory system
0.000 0.890 0.110
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.890 0.110
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.890 0.110
J15.4 Pneumonia due to other streptococci
0.000 0.892 0.108
J15.9 Bacterial pneumonia, unspecified
0.000 0.893 0.107
I05.1 Rheumatic mitral insufficiency
0.000 0.894 0.105
J21.9 Acute bronchiolitis, unspecified
0.000 0.895 0.105
J12.9 Viral pneumonia, unspecified
0.000 0.895 0.104
J04.1 Acute tracheitis
0.000 0.897 0.103
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.897 0.102
J20.9 Acute bronchitis, unspecified
0.000 0.898 0.101
J04.2 Acute laryngotracheitis
0.000 0.899 0.101
J45.0 Predominantly allergic asthma
0.000 0.900 0.100
I27.2 Other secondary pulmonary hypertension
0.000 0.901 0.099
I09.8 Other specified rheumatic heart diseases
0.000 0.901 0.099
I09.2 Chronic rheumatic pericarditis
0.000 0.901 0.099
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.901 0.099
I09.0 Rheumatic myocarditis
0.000 0.901 0.099
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.901 0.098
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.902 0.097
J01.8 Other acute sinusitis
0.000 0.903 0.097
J01.4 Acute pansinusitis
0.000 0.903 0.097
J01.3 Acute sphenoidal sinusitis
0.000 0.903 0.097
J01.1 Acute frontal sinusitis
0.000 0.903 0.097
J01.0 Acute maxillary sinusitis
0.000 0.905 0.095
I95 Hypotension
0.000 0.906 0.094
J15.1 Pneumonia due to Pseudomonas
0.000 0.906 0.094
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.906 0.094
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.906 0.094
I98.0 Cardiovascular syphilis
0.000 0.906 0.094
J82 Pulmonary eosinophilia, not elsewhere classified
0.001 0.908 0.091
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.908 0.092
J47 Bronchiectasis
0.000 0.910 0.090
J17.3 Pneumonia in parasitic diseases
0.000 0.910 0.090
J01.9 Acute sinusitis, unspecified
0.000 0.911 0.089
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.911 0.089
J02.0 Streptococcal pharyngitis
0.000 0.912 0.088
I07.9 Tricuspid valve disease, unspecified
0.000 0.913 0.087
I07.8 Other tricuspid valve diseases
0.000 0.913 0.087
I07.2 Tricuspid stenosis with insufficiency
0.000 0.913 0.087
I07.0 Tricuspid stenosis
0.000 0.913 0.087
I95.1 Orthostatic hypotension
0.000 0.913 0.087
J17.2 Pneumonia in mycoses
0.000 0.913 0.087
I05.8 Other mitral valve diseases
0.000 0.913 0.087
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.913 0.087
J03.0 Streptococcal tonsillitis
0.000 0.913 0.087
I07.1 Tricuspid insufficiency
0.000 0.913 0.087
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.914 0.086
I06.8 Other rheumatic aortic valve diseases
0.000 0.914 0.086
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.914 0.086
I06.1 Rheumatic aortic insufficiency
0.000 0.914 0.086
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.914 0.086
I97.0 Postcardiotomy syndrome
0.000 0.914 0.086
I05.0 Mitral stenosis
0.000 0.914 0.086
J11.8 Influenza with other manifestations, virus not identified
0.000 0.915 0.084
I06.0 Rheumatic aortic stenosis
0.000 0.916 0.084
J01.2 Acute ethmoidal sinusitis
0.000 0.916 0.084
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.918 0.082
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.918 0.082
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.919 0.081
J06.0 Acute laryngopharyngitis
0.000 0.919 0.081
J81 Pulmonary oedema
0.000 0.922 0.078
J04.0 Acute laryngitis
0.000 0.922 0.078
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.923 0.076
I97.1 Other functional disturbances following cardiac surgery
0.000 0.924 0.076
J11.0 Influenza with pneumonia, virus not identified
0.000 0.925 0.074
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.926 0.074
I95.8 Other hypotension
0.000 0.926 0.074
J80 Adult respiratory distress syndrome
0.001 0.929 0.070
I05.9 Mitral valve disease, unspecified
0.000 0.929 0.071
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.929 0.071
I05.2 Mitral stenosis with insufficiency
0.000 0.930 0.070
I63 Cerebral infarction
0.000 0.932 0.068
J02.9 Acute pharyngitis, unspecified
0.000 0.935 0.065
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.936 0.064
I65.1 Occlusion and stenosis of basilar artery
0.000 0.940 0.060
I10-I15 Hypertensive diseases
0.000 0.941 0.059
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.942 0.058
I95.0 Idiopathic hypotension
0.000 0.946 0.054
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.948 0.052
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.949 0.050
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.951 0.049
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.951 0.049
I65.2 Occlusion and stenosis of carotid artery
0.000 0.953 0.046
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.954 0.045
J03.9 Acute tonsillitis, unspecified
0.000 0.954 0.046
J18.0 Bronchopneumonia, unspecified
0.000 0.956 0.044
I13 Hypertensive heart and renal disease
0.000 0.957 0.043
I15 Secondary hypertension
0.000 0.960 0.040
Z50.1 Other physical therapy
0.000 0.964 0.036
N64 Other disorders of breast
0.033 0.967 0.000
Z50 Care involving use of rehabilitation procedures
0.000 0.967 0.033
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.968 0.032
I11 Hypertensive heart disease
0.000 0.968 0.032
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.969 0.031
N64.5 Other signs and symptoms in breast
0.031 0.969 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.969 0.031
N64.1 Fat necrosis of breast
0.031 0.969 0.000
N64.8 Other specified disorders of breast
0.031 0.969 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.969 0.031
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.969 0.031
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.969 0.031
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.969 0.031
Z50.2 Alcohol rehabilitation
0.000 0.969 0.031
I15.1 Hypertension secondary to other renal disorders
0.000 0.969 0.031
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.969 0.031
I12 Hypertensive renal disease
0.000 0.970 0.030
Z50.5 Speech therapy
0.000 0.970 0.030
N64.4 Mastodynia
0.029 0.971 0.000
N64.9 Disorder of breast, unspecified
0.029 0.971 0.000
I15.8 Other secondary hypertension
0.000 0.971 0.029
I15.2 Hypertension secondary to endocrine disorders
0.000 0.971 0.029
I15.9 Seconday hypertension, unspecified
0.000 0.971 0.028
I95.9 Hypotension, unspecified
0.000 0.972 0.028
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.972 0.028
N64.3 Galactorrhoea not associated with childbirth
0.026 0.974 0.000
E11.3 With ophthalmic complications
0.000 0.974 0.026
E11 Non-insulin-dependent diabetes mellitus
0.000 0.975 0.025
C67 Malignant neoplasm of bladder
0.000 0.975 0.025
C67.2 Lateral wall of bladder
0.000 0.975 0.025
C67.6 Ureteric orifice
0.000 0.975 0.025
N64.2 Atrophy of breast
0.024 0.976 0.000
N64.0 Fissure and fistula of nipple
0.024 0.976 0.000
I95.2 Hypotension due to drugs
0.000 0.976 0.023

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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