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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs67455183
log Bayes Factor = 5.50415
Chromosome 8   position 10,145,925  (GRCh37) Explore rs67455183 on Ensembl!
Variant rs67455183 is part of Cluster X0282

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44 Other chronic obstructive pulmonary disease
0.000 0.004 0.996
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.005 0.995
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.012 0.988
J40-J47 Chronic lower respiratory diseases
0.000 0.012 0.988
J43 Emphysema
0.000 0.021 0.979
J43.9 Emphysema, unspecified
0.000 0.026 0.974
Z86.7 Personal history of diseases of the circulatory system
0.000 0.030 0.970
Z86 Personal history of certain other diseases
0.000 0.031 0.969
I10-I15 Hypertensive diseases
0.000 0.033 0.967
I60-I69 Cerebrovascular diseases
0.000 0.033 0.967
Chapter IX Diseases of the circulatory system
0.000 0.033 0.967
I10 Essential (primary) hypertension
0.000 0.034 0.966
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.036 0.964
Z86.4 Personal history of psychoactive substance abuse
0.000 0.039 0.961
I30-I52 Other forms of heart disease
0.000 0.040 0.960
I34 Nonrheumatic mitral valve disorders
0.000 0.040 0.960
Z86.5 Personal history of other mental and behavioural disorders
0.000 0.049 0.951
I34.0 Mitral (valve) insufficiency
0.000 0.051 0.949
J46 Status asthmaticus
0.000 0.069 0.931
I62 Other nontraumatic intracranial haemorrhage
0.000 0.074 0.926
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.082 0.918
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.084 0.916
I34.1 Mitral (valve) prolapse
0.000 0.087 0.913
I63 Cerebral infarction
0.000 0.087 0.913
I38 Endocarditis, valve unspecified
0.000 0.098 0.902
J47 Bronchiectasis
0.000 0.106 0.894
I12 Hypertensive renal disease
0.000 0.113 0.887
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.117 0.883
I45 Other conduction disorders
0.000 0.121 0.879
I42 Cardiomyopathy
0.000 0.143 0.857
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.153 0.847
I51 Complications and ill-defined descriptions of heart disease
0.000 0.183 0.817
I63.8 Other cerebral infarction
0.000 0.188 0.812
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.190 0.810
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.191 0.809
I42.0 Dilated cardiomyopathy
0.000 0.196 0.804
I30 Acute pericarditis
0.000 0.207 0.793
I12.0 Hypertensive renal disease with renal failure
0.000 0.209 0.791
Z86.6 Personal history of diseases of the nervous system and sense organs
0.000 0.219 0.781
I45.2 Bifascicular block
0.000 0.228 0.772
J40 Bronchitis, not specified as acute or chronic
0.000 0.229 0.771
I45.5 Other specified heart block
0.000 0.233 0.767
I33 Acute and subacute endocarditis
0.000 0.239 0.761
I51.8 Other ill-defined heart diseases
0.000 0.249 0.751
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.249 0.751
I63.9 Cerebral infarction, unspecified
0.000 0.254 0.746
I51.0 Cardiac septal defect, acquired
0.000 0.261 0.739
I12.9 Hypertensive renal disease without renal failure
0.000 0.264 0.736
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.280 0.720
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.287 0.713
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.290 0.710
I45.9 Conduction disorder, unspecified
0.000 0.291 0.709
J41 Simple and mucopurulent chronic bronchitis
0.000 0.292 0.708
I15 Secondary hypertension
0.000 0.295 0.705
I37 Pulmonary valve disorders
0.000 0.298 0.702
J43.8 Other emphysema
0.000 0.298 0.702
J43.1 Panlobular emphysema
0.000 0.298 0.702
J43.0 MacLeod's syndrome
0.000 0.298 0.702
I13 Hypertensive heart and renal disease
0.000 0.307 0.693
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.307 0.693
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.307 0.693
I74 Arterial embolism and thrombosis
0.000 0.307 0.693
I52 Other heart disorders in diseases classified elsewhere
0.000 0.311 0.689
I48 Atrial fibrillation and flutter
0.000 0.311 0.689
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.311 0.689
I41 Myocarditis in diseases classified elsewhere
0.000 0.311 0.689
I40 Acute myocarditis
0.000 0.311 0.689
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.311 0.689
I32 Pericarditis in diseases classified elsewhere
0.000 0.311 0.689
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.312 0.688
I46 Cardiac arrest
0.000 0.315 0.685
I51.4 Myocarditis, unspecified
0.000 0.316 0.684
I61 Intracerebral haemorrhage
0.000 0.318 0.682
I36 Nonrheumatic tricuspid valve disorders
0.000 0.320 0.680
I45.3 Trifascicular block
0.000 0.325 0.675
I62.1 Nontraumatic extradural haemorrhage
0.000 0.336 0.664
J43.2 Centrilobular emphysema
0.000 0.336 0.664
I45.4 Nonspecific intraventricular block
0.000 0.338 0.662
I99 Other and unspecified disorders of circulatory system
0.000 0.338 0.662
I42.6 Alcoholic cardiomyopathy
0.000 0.341 0.659
I00-I02 Acute rheumatic fever
0.000 0.342 0.658
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.345 0.655
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.345 0.654
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.345 0.654
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.345 0.654
I30.9 Acute pericarditis, unspecified
0.000 0.352 0.648
I69 Sequelae of cerebrovascular disease
0.000 0.360 0.640
I45.8 Other specified conduction disorders
0.000 0.365 0.635
I45.0 Right fascicular block
0.000 0.370 0.630
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.377 0.623
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.377 0.623
I33.0 Acute and subacute infective endocarditis
0.000 0.382 0.618
I05-I09 Chronic rheumatic heart diseases
0.000 0.382 0.618
I42.8 Other cardiomyopathies
0.000 0.383 0.617
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.385 0.614
I42.5 Other restrictive cardiomyopathy
0.000 0.385 0.614
I42.4 Endocardial fibroelastosis
0.000 0.385 0.614
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.385 0.614
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.386 0.614
I30.1 Infective pericarditis
0.000 0.393 0.606
J42 Unspecified chronic bronchitis
0.000 0.396 0.604
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.398 0.602
I74.8 Embolism and thrombosis of other arteries
0.000 0.411 0.589
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.412 0.588
I51.5 Myocardial degeneration
0.000 0.414 0.586
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.414 0.586
I51.6 Cardiovascular disease, unspecified
0.000 0.414 0.586
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.414 0.585
I74.5 Embolism and thrombosis of iliac artery
0.000 0.420 0.580
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.422 0.578
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.426 0.573
I73 Other peripheral vascular diseases
0.000 0.431 0.569
I30.8 Other forms of acute pericarditis
0.000 0.431 0.568
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.431 0.568
I11 Hypertensive heart disease
0.000 0.437 0.563
I80 Phlebitis and thrombophlebitis
0.000 0.442 0.558
I45.6 Preexcitation syndrome
0.000 0.446 0.554
I33.9 Acute endocarditis, unspecified
0.000 0.454 0.545
I15.9 Seconday hypertension, unspecified
0.000 0.472 0.527
I42.2 Other hypertrophic cardiomyopathy
0.000 0.481 0.519
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.481 0.518
I37.1 Pulmonary valve insufficiency
0.000 0.483 0.517
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.492 0.508
J41.1 Mucopurulent chronic bronchitis
0.000 0.492 0.508
J41.0 Simple chronic bronchitis
0.000 0.492 0.508
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.493 0.507
I15.8 Other secondary hypertension
0.000 0.494 0.505
I15.2 Hypertension secondary to endocrine disorders
0.000 0.494 0.505
I15.0 Renovascular hypertension
0.000 0.494 0.505
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.494 0.505
I37.9 Pulmonary valve disorder, unspecified
0.000 0.496 0.503
I37.8 Other pulmonary valve disorders
0.000 0.496 0.503
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.496 0.503
I37.0 Pulmonary valve stenosis
0.000 0.496 0.503
I46.9 Cardiac arrest, unspecified
0.000 0.499 0.501
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.500 0.500
I70 Atherosclerosis
0.000 0.502 0.498
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.503 0.497
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.503 0.497
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.503 0.497
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.503 0.497
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.503 0.497
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.503 0.497
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.503 0.497
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.503 0.497
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.503 0.497
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.503 0.497
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.503 0.497
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.503 0.497
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.503 0.497
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.503 0.497
I68.0 Cerebral amyloid angiopathy
0.000 0.503 0.497
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.503 0.497
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.503 0.497
I61.8 Other intracerebral haemorrhage
0.000 0.505 0.495
I15.1 Hypertension secondary to other renal disorders
0.000 0.506 0.494
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.506 0.494
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.506 0.494
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.506 0.494
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I40.9 Acute myocarditis, unspecified
0.000 0.506 0.494
I40.8 Other acute myocarditis
0.000 0.506 0.494
I40.1 Isolated myocarditis
0.000 0.506 0.494
I40.0 Infective myocarditis
0.000 0.506 0.494
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.506 0.494
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.506 0.494
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.506 0.494
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.506 0.494
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.506 0.494
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.506 0.494
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.506 0.494
I48.4 Atypical atrial flutter
0.000 0.506 0.494
I48.3 Typical atrial flutter
0.000 0.506 0.494
I48.2 Chronic atrial fibrillation
0.000 0.506 0.494
I48.1 Persistent atrial fibrillation
0.000 0.506 0.494
I48.0 Paroxysmal atrial fibrillation
0.000 0.506 0.494
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.506 0.494
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.506 0.494
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.506 0.493
I46.1 Sudden cardiac death, so described
0.000 0.509 0.491
I08 Multiple valve diseases
0.000 0.509 0.491
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.511 0.489
I83 Varicose veins of lower extremities
0.000 0.512 0.488
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.512 0.488
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.512 0.488
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.512 0.488
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.512 0.488
I60 Subarachnoid haemorrhage
0.000 0.514 0.486
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.516 0.484
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.517 0.483
I72 Other aneurysm
0.000 0.520 0.480
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.520 0.480
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.522 0.478
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.522 0.478
I46.0 Cardiac arrest with successful resuscitation
0.000 0.524 0.476
I02 Rheumatic chorea
0.000 0.528 0.472
I01 Rheumatic fever with heart involvement
0.000 0.528 0.472
I82 Other venous embolism and thrombosis
0.000 0.531 0.469
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.532 0.468
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.534 0.466
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.536 0.464
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.536 0.463
I73.8 Other specified peripheral vascular diseases
0.000 0.539 0.461
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.541 0.459
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.542 0.458
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.544 0.456
I89.0 Lymphoedema, not elsewhere classified
0.000 0.548 0.452
I09 Other rheumatic heart diseases
0.000 0.548 0.452
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.549 0.451
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.555 0.445
I31 Other diseases of pericardium
0.000 0.556 0.444
I67 Other cerebrovascular diseases
0.000 0.563 0.437
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.563 0.437
I00 Rheumatic fever without mention of heart involvement
0.000 0.563 0.436
I72.8 Aneurysm of other specified arteries
0.000 0.571 0.428
I87 Other disorders of veins
0.000 0.572 0.428
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.572 0.428
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.574 0.425
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.575 0.425
I69.3 Sequelae of cerebral infarction
0.000 0.575 0.425
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.576 0.424
I73.9 Peripheral vascular disease, unspecified
0.000 0.576 0.424
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.582 0.418
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.584 0.416
I60.8 Other subarachnoid haemorrhage
0.000 0.585 0.414
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.589 0.411
I79.1 Aortitis in diseases classified elsewhere
0.000 0.589 0.411
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.589 0.411
I07 Rheumatic tricuspid valve diseases
0.000 0.589 0.411
I06 Rheumatic aortic valve diseases
0.000 0.591 0.409
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.592 0.408
I08.8 Other multiple valve diseases
0.000 0.592 0.408
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.596 0.403
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.600 0.400
I45.1 Other and unspecified right bundle-branch block
0.000 0.603 0.397
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.604 0.396
I73.0 Raynaud's syndrome
0.000 0.611 0.389
I72.0 Aneurysm of carotid artery
0.000 0.612 0.388
I70.1 Atherosclerosis of renal artery
0.000 0.613 0.387
I88 Nonspecific lymphadenitis
0.000 0.615 0.385
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.620 0.380
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.626 0.373
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.629 0.371
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.631 0.369
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.632 0.367
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.634 0.366
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.636 0.364
I97.0 Postcardiotomy syndrome
0.000 0.636 0.364
I82.8 Embolism and thrombosis of other specified veins
0.000 0.637 0.363
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.638 0.362
I05 Rheumatic mitral valve diseases
0.000 0.640 0.360
I70.0 Atherosclerosis of aorta
0.000 0.642 0.358
I70.9 Generalised and unspecified atherosclerosis
0.000 0.643 0.357
I70.8 Atherosclerosis of other arteries
0.000 0.643 0.357
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.644 0.356
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.646 0.353
I08.9 Multiple valve disease, unspecified
0.000 0.648 0.352
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.651 0.348
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.651 0.348
I82.2 Embolism and thrombosis of vena cava
0.000 0.651 0.348
I42.9 Cardiomyopathy, unspecified
0.000 0.652 0.348
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.656 0.344
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.656 0.344
I72.1 Aneurysm of artery of upper extremity
0.000 0.656 0.344
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.659 0.341
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.660 0.339
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.662 0.338
I01.8 Other acute rheumatic heart disease
0.000 0.662 0.338
I01.2 Acute rheumatic myocarditis
0.000 0.662 0.338
I01.1 Acute rheumatic endocarditis
0.000 0.662 0.338
I01.0 Acute rheumatic pericarditis
0.000 0.662 0.338
I02.9 Rheumatic chorea without heart involvement
0.000 0.662 0.338
I02.0 Rheumatic chorea with heart involvement
0.000 0.662 0.338
I77 Other disorders of arteries and arterioles
0.000 0.662 0.338
I82.1 Thrombophlebitis migrans
0.000 0.664 0.336
I82.0 Budd-Chiari syndrome
0.000 0.664 0.336
I09.9 Rheumatic heart disease, unspecified
0.000 0.667 0.333
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.671 0.329
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.675 0.325
I09.8 Other specified rheumatic heart diseases
0.000 0.676 0.324
I09.2 Chronic rheumatic pericarditis
0.000 0.676 0.324
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.676 0.324
I09.0 Rheumatic myocarditis
0.000 0.676 0.324
I31.8 Other specified diseases of pericardium
0.000 0.681 0.319
I31.2 Haemopericardium, not elsewhere classified
0.000 0.681 0.319
I31.1 Chronic constrictive pericarditis
0.000 0.681 0.319
I81 Portal vein thrombosis
0.000 0.682 0.318
I28 Other diseases of pulmonary vessels
0.000 0.682 0.318
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.682 0.317
I72.9 Aneurysm of unspecified site
0.000 0.683 0.316
I97.1 Other functional disturbances following cardiac surgery
0.000 0.685 0.314
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.686 0.314
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.686 0.314
I67.5 Moyamoya disease
0.000 0.686 0.314
I67.4 Hypertensive encephalopathy
0.000 0.686 0.314
I67.3 Progressive vascular leukoencephalopathy
0.000 0.686 0.314
I71 Aortic aneurysm and dissection
0.000 0.688 0.312
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.693 0.307
I87.9 Disorder of vein, unspecified
0.000 0.693 0.307
I87.0 Postphlebitic syndrome
0.000 0.693 0.307
J45 Asthma
0.000 0.695 0.305
I82.3 Embolism and thrombosis of renal vein
0.000 0.696 0.304
I77.1 Stricture of artery
0.000 0.697 0.303
I67.8 Other specified cerebrovascular diseases
0.000 0.698 0.302
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.701 0.298
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.701 0.298
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.701 0.298
I65.1 Occlusion and stenosis of basilar artery
0.000 0.701 0.298
I67.9 Cerebrovascular disease, unspecified
0.000 0.702 0.298
I31.9 Disease of pericardium, unspecified
0.000 0.703 0.296
I31.0 Chronic adhesive pericarditis
0.000 0.705 0.295
I07.9 Tricuspid valve disease, unspecified
0.000 0.705 0.295
I07.8 Other tricuspid valve diseases
0.000 0.705 0.295
I07.2 Tricuspid stenosis with insufficiency
0.000 0.705 0.295
I07.0 Tricuspid stenosis
0.000 0.705 0.295
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.706 0.294
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.706 0.294
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.706 0.293
I06.8 Other rheumatic aortic valve diseases
0.000 0.706 0.293
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.706 0.293
I06.1 Rheumatic aortic insufficiency
0.000 0.706 0.293
I87.8 Other specified disorders of veins
0.000 0.707 0.293
I72.2 Aneurysm of renal artery
0.000 0.709 0.291
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.715 0.285
I95 Hypotension
0.000 0.716 0.284
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.717 0.282
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.718 0.282
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.721 0.278
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.722 0.277
I67.2 Cerebral atherosclerosis
0.000 0.722 0.277
I88.8 Other nonspecific lymphadenitis
0.000 0.724 0.276
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.724 0.276
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.724 0.276
Z86.0 Personal history of other neoplasms
0.000 0.731 0.269
I08.0 Disorders of both mitral and aortic valves
0.000 0.733 0.267
I72.4 Aneurysm of artery of lower extremity
0.000 0.735 0.265
I07.1 Tricuspid insufficiency
0.000 0.737 0.263
I06.0 Rheumatic aortic stenosis
0.000 0.740 0.260
I05.8 Other mitral valve diseases
0.000 0.742 0.258
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.742 0.258
I05.0 Mitral stenosis
0.000 0.742 0.258
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.743 0.257
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.744 0.256
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.744 0.256
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.744 0.256
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.744 0.256
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.745 0.255
I05.1 Rheumatic mitral insufficiency
0.000 0.746 0.254
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.746 0.253
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.746 0.253
I98.0 Cardiovascular syphilis
0.000 0.746 0.253
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.750 0.250
I85 Oesophageal varices
0.000 0.750 0.250
I05.2 Mitral stenosis with insufficiency
0.000 0.755 0.245
I77.5 Necrosis of artery
0.000 0.757 0.243
I77.4 Coeliac artery compression syndrome
0.000 0.757 0.243
I77.3 Arterial fibromuscular dysplasia
0.000 0.757 0.243
I77.2 Rupture of artery
0.000 0.757 0.243
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.759 0.241
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.760 0.240
I27 Other pulmonary heart diseases
0.000 0.761 0.239
I71.0 Dissection of aorta [any part]
0.000 0.767 0.233
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.772 0.228
I28.1 Aneurysm of pulmonary artery
0.000 0.772 0.228
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.772 0.228
I72.3 Aneurysm of iliac artery
0.000 0.772 0.228
I28.8 Other specified diseases of pulmonary vessels
0.000 0.773 0.226
I78 Diseases of capillaries
0.000 0.773 0.226
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.774 0.225
I95.0 Idiopathic hypotension
0.000 0.775 0.225
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.776 0.224
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.776 0.224
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.776 0.224
J45.8 Mixed asthma
0.000 0.781 0.219
J45.1 Nonallergic asthma
0.000 0.781 0.219
I26 Pulmonary embolism
0.000 0.782 0.218
I89.1 Lymphangitis
0.001 0.786 0.214
I87.1 Compression of vein
0.000 0.787 0.213
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.789 0.211
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.789 0.211
I95.2 Hypotension due to drugs
0.000 0.790 0.210
I44 Atrioventricular and left bundle-branch block
0.000 0.791 0.209
I86 Varicose veins of other sites
0.001 0.791 0.208
I05.9 Mitral valve disease, unspecified
0.000 0.796 0.204
I27.2 Other secondary pulmonary hypertension
0.000 0.801 0.199
I95.1 Orthostatic hypotension
0.000 0.804 0.196
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.807 0.192
I77.0 Arteriovenous fistula, acquired
0.000 0.809 0.191
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.818 0.182
I31.3 Pericardial effusion (noninflammatory)
0.000 0.821 0.179
I35 Nonrheumatic aortic valve disorders
0.000 0.822 0.178
I27.1 Kyphoscoliotic heart disease
0.000 0.829 0.171
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.830 0.170
J45.0 Predominantly allergic asthma
0.000 0.834 0.166
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.835 0.165
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.835 0.165
J44.8 Other specified chronic obstructive pulmonary disease
0.001 0.836 0.163
I78.9 Disease of capillaries, unspecified
0.000 0.837 0.162
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.841 0.158
I44.3 Other and unspecified atrioventricular block
0.000 0.842 0.158
I77.8 Other specified disorders of arteries and arterioles
0.000 0.842 0.158
I95.8 Other hypotension
0.000 0.842 0.158
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.846 0.153
I47 Paroxysmal tachycardia
0.000 0.848 0.152
I44.5 Left posterior fascicular block
0.000 0.850 0.150
I44.4 Left anterior fascicular block
0.000 0.850 0.150
I86.4 Gastric varices
0.000 0.850 0.150
I86.3 Vulval varices
0.001 0.850 0.149
I86.0 Sublingual varices
0.001 0.850 0.149
I51.7 Cardiomegaly
0.000 0.851 0.149
I27.9 Pulmonary heart disease, unspecified
0.000 0.851 0.148
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.852 0.148
I85.0 Oesophageal varices with bleeding
0.000 0.853 0.147
I77.6 Arteritis, unspecified
0.000 0.853 0.146
I27.0 Primary pulmonary hypertension
0.000 0.854 0.146
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.855 0.145
I44.2 Atrioventricular block, complete
0.000 0.855 0.145
I78.8 Other diseases of capillaries
0.000 0.857 0.143
I49 Other cardiac arrhythmias
0.000 0.859 0.141
I44.6 Other and unspecified fascicular block
0.000 0.863 0.137
I35.8 Other aortic valve disorders
0.000 0.866 0.134
I67.1 Cerebral aneurysm, nonruptured
0.000 0.866 0.134
I86.2 Pelvic varices
0.001 0.867 0.132
I50 Heart failure
0.000 0.869 0.131
I86.8 Varicose veins of other specified sites
0.001 0.872 0.127
I44.0 Atrioventricular block, first degree
0.000 0.875 0.125
I51.9 Heart disease, unspecified
0.001 0.879 0.119
I49.8 Other specified cardiac arrhythmias
0.000 0.889 0.111
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.890 0.109
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.892 0.107
I49.5 Sick sinus syndrome
0.000 0.892 0.108
I35.1 Aortic (valve) insufficiency
0.000 0.893 0.107
I27.8 Other specified pulmonary heart diseases
0.001 0.895 0.104
I49.2 Junctional premature depolarisation
0.000 0.898 0.101
I47.0 Reentry ventricular arrhythmia
0.000 0.904 0.096
I49.1 Atrial premature depolarisation
0.000 0.904 0.096
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.907 0.093
I44.1 Atrioventricular block, second degree
0.000 0.914 0.086
I85.9 Oesophageal varices without bleeding
0.000 0.915 0.084
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.919 0.081
I49.4 Other and unspecified premature depolarisation
0.000 0.919 0.081
I78.1 Naevus, nonneoplastic
0.000 0.920 0.080
T39.1 4-Aminophenol derivatives
0.000 0.924 0.076
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.924 0.076
T42.4 Benzodiazepines
0.000 0.928 0.072
I35.9 Aortic valve disorder, unspecified
0.000 0.929 0.070
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.929 0.071
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.930 0.070
I65.2 Occlusion and stenosis of carotid artery
0.000 0.931 0.069
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.931 0.069
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.941 0.059
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.941 0.059
T39.0 Salicylates
0.000 0.941 0.059
I49.9 Cardiac arrhythmia, unspecified
0.000 0.942 0.058
T36 Poisoning by systemic antibiotics
0.000 0.944 0.056
I86.1 Scrotal varices
0.001 0.944 0.055
I49.0 Ventricular fibrillation and flutter
0.000 0.945 0.055
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.945 0.055
T39.4 Antirheumatics, not elsewhere classified
0.000 0.945 0.055
T39.2 Pyrazolone derivatives
0.000 0.945 0.055
T42.1 Iminostilbenes
0.000 0.946 0.054
I47.2 Ventricular tachycardia
0.000 0.946 0.054
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.947 0.053
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.947 0.052
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.949 0.051
T42.0 Hydantoin derivatives
0.000 0.949 0.051
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.949 0.051
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.949 0.051
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.949 0.051
T42.3 Barbiturates
0.000 0.949 0.051
T42.2 Succinimides and oxazolidinediones
0.000 0.949 0.051
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.950 0.050
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.950 0.050
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.950 0.050
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.950 0.050
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.950 0.050
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.951 0.049
I44.7 Left bundle-branch block, unspecified
0.000 0.951 0.049
T45.5 Anticoagulants
0.000 0.952 0.048
T45.0 Antiallergic and antiemetic drugs
0.000 0.953 0.047
T36.0 Penicillins
0.000 0.954 0.046
I50.0 Congestive heart failure
0.000 0.954 0.046
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.954 0.046
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.954 0.046
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.957 0.043
T45.8 Other primarily systemic and haematological agents
0.000 0.957 0.043
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.957 0.043
T45.6 Fibrinolysis-affecting drugs
0.000 0.957 0.043
T45.4 Iron and its compounds
0.000 0.957 0.043
T45.3 Enzymes, not elsewhere classified
0.000 0.957 0.043
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.957 0.043
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.958 0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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