TreeWAS – Variant ID: rs678069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.1 Aortic (valve) insufficiency	0.042	0.958	0.000
I35 Nonrheumatic aortic valve disorders	0.031	0.969	0.000
I35.8 Other aortic valve disorders	0.028	0.972	0.000
I35.0 Aortic (valve) stenosis	0.028	0.972	0.000
I35.9 Aortic valve disorder, unspecified	0.025	0.975	0.000
N90.5 Atrophy of vulva	0.000	0.984	0.016
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.984	0.016
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.984	0.016
N90.7 Vulvar cyst	0.000	0.985	0.015
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.015	0.985	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.014	0.986	0.000
T39.1 4-Aminophenol derivatives	0.014	0.986	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.987	0.013
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.013	0.987	0.000
N90.6 Hypertrophy of vulva	0.000	0.987	0.013
I35.2 Aortic (valve) stenosis with insufficiency	0.013	0.987	0.000
N90.3 Dysplasia of vulva, unspecified	0.000	0.988	0.012
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.988	0.012
N90.1 Moderate vulvar dysplasia	0.000	0.988	0.012
N90.0 Mild vulvar dysplasia	0.000	0.988	0.012
T36-T50 Poisoning by drugs, medicaments and biological substances	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T39.0 Salicylates	0.011	0.989	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
I44.2 Atrioventricular block, complete	0.000	0.989	0.011
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.011	0.989	0.000
T39.4 Antirheumatics, not elsewhere classified	0.011	0.989	0.000
T39.2 Pyrazolone derivatives	0.011	0.989	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.010	0.990	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
T45.0 Antiallergic and antiemetic drugs	0.009	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.009	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.991	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
T36 Poisoning by systemic antibiotics	0.008	0.991	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.992	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
T45.5 Anticoagulants	0.008	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
N90.4 Leukoplakia of vulva	0.000	0.992	0.008
C85.1 B-cell lymphoma, unspecified	0.008	0.992	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
T46.1 Calcium-channel blockers	0.008	0.992	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.992	0.008
T45.9 Primarily systemic and haematological agent, unspecified	0.007	0.992	0.000
T45.8 Other primarily systemic and haematological agents	0.007	0.992	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.992	0.000
T45.6 Fibrinolysis-affecting drugs	0.007	0.992	0.000
T45.4 Iron and its compounds	0.007	0.992	0.000
T45.3 Enzymes, not elsewhere classified	0.007	0.992	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.992	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.007	0.992	0.000
I44.0 Atrioventricular block, first degree	0.000	0.993	0.007
T50.8 Diagnostic agents	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.4 Drugs affecting uric acid metabolism	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.007	0.993	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
T48.5 Anti-common-cold drugs	0.007	0.993	0.000
T48.4 Expectorants	0.007	0.993	0.000
T48.3 Antitussives	0.007	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
T48.0 Oxytocic drugs	0.007	0.993	0.000
I44.1 Atrioventricular block, second degree	0.000	0.993	0.007
C67.9 Bladder, unspecified	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.007	0.993	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.993	0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.4 Other laxatives	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
I95.1 Orthostatic hypotension	0.006	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
I44.6 Other and unspecified fascicular block	0.000	0.994	0.006
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
I44.5 Left posterior fascicular block	0.000	0.994	0.006
I44.4 Left anterior fascicular block	0.000	0.994	0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.994	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.995	0.005
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.995	0.000
T42.3 Barbiturates	0.004	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.995	0.000
T42.0 Hydantoin derivatives	0.004	0.995	0.000
T42.1 Iminostilbenes	0.004	0.995	0.000
T42.4 Benzodiazepines	0.004	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.004	0.996	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.996	0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.004	0.996	0.000
D37.5 Rectum	0.004	0.996	0.000
K83.0 Cholangitis	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.003	0.996	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
C67 Malignant neoplasm of bladder	0.000	0.997	0.003
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.003	0.997	0.000
C85.0 Lymphosarcoma	0.003	0.997	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.997	0.003
N86 Erosion and ectropion of cervix uteri	0.000	0.997	0.003
Z96.0 Presence of urogenital implants	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
D37.9 Digestive organ, unspecified	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
Z95.8 Presence of other cardiac and vascular implants and grafts	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.000	0.997	0.003
C85.7 Other specified types of non-Hodgkin's lymphoma	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
N88 Other noninflammatory disorders of cervix uteri	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
H11.0 Pterygium	0.003	0.997	0.000
C67.6 Ureteric orifice	0.000	0.997	0.003
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.997	0.000
C67.5 Bladder neck	0.000	0.997	0.003
N80.1 Endometriosis of ovary	0.000	0.997	0.003
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
C67.7 Urachus	0.000	0.997	0.003
C67.0 Trigone of bladder	0.000	0.997	0.003
H11.1 Conjunctival degenerations and deposits	0.003	0.997	0.000
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.003	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.997	0.003
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.997	0.000
H11.3 Conjunctival haemorrhage	0.002	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.997	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.997	0.000
H11.2 Conjunctival scars	0.002	0.998	0.000
D37.4 Colon	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.000	0.998	0.002
N88.3 Incompetence of cervix uteri	0.000	0.998	0.002
N88.1 Old laceration of cervix uteri	0.000	0.998	0.002
N88.0 Leukoplakia of cervix uteri	0.000	0.998	0.002
Q53 Undescended testicle	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
H11.9 Disorder of conjunctiva, unspecified	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.001
C91 Lymphoid leukaemia	0.001	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
N80.9 Endometriosis, unspecified	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
C67.1 Dome of bladder	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
I95 Hypotension	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.002	0.998	0.000
N80 Endometriosis	0.000	0.998	0.002
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
C91.9 Lymphoid leukaemia, unspecified	0.001	0.998	0.001
C91.8 Mature B-cell leukaemia Burkitt-type	0.001	0.998	0.001
C91.7 Other lymphoid leukaemia	0.001	0.998	0.001
C91.6 Prolymphocytic leukaemia of T-cell type	0.001	0.998	0.001
C91.5 Adult T-cell leukaemia	0.001	0.998	0.001
C91.4 Hairy-cell leukaemia	0.000	0.998	0.001
C91.3 Prolymphocytic leukaemia	0.001	0.998	0.001
C91.2 Subacute lymphocytic leukaemia	0.001	0.998	0.001
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
N13.4 Hydroureter	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.000	0.998	0.002
Z95.4 Presence of other heart-valve replacement	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.998	0.002
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
I95.0 Idiopathic hypotension	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
L05 Pilonidal cyst	0.000	0.998	0.002
C91.0 Acute lymphoblastic leukaemia	0.001	0.998	0.001
N80.8 Other endometriosis	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.5 Duplication of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.2 Congenital megaloureter	0.001	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.998	0.000
Q64.4 Malformation of urachus	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.998	0.000
Q64.0 Epispadias	0.001	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
N80.6 Endometriosis in cutaneous scar	0.000	0.998	0.002
N80.5 Endometriosis of intestine	0.000	0.998	0.002
N80.4 Endometriosis of rectovaginal septum and vagina	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
M17 Gonarthrosis [arthrosis of knee]	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
I95.8 Other hypotension	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.998	0.000
Q23.2 Congenital mitral stenosis	0.001	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.2 Mastocytosis	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
Q54.9 Hypospadias, unspecified	0.001	0.998	0.000
Z03.8 Observation for other suspected diseases and conditions	0.000	0.998	0.002
M24 Other specific joint derangements	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.998	0.000
Q79.4 Prune belly syndrome	0.001	0.998	0.000
Q79.3 Gastroschisis	0.001	0.998	0.000
Q79.2 Exomphalos	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.001	0.998	0.000
N80.2 Endometriosis of Fallopian tube	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.998	0.000
Q87.4 Marfan's syndrome	0.001	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.001	0.998	0.000
Q04 Other congenital malformations of brain	0.001	0.998	0.000
Q03 Congenital hydrocephalus	0.001	0.998	0.000
Q01 Encephalocele	0.001	0.998	0.000
Q00 Anencephaly and similar malformations	0.001	0.998	0.000
Q02 Microcephaly	0.001	0.998	0.000
Q17 Other congenital malformations of ear	0.001	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.998	0.000
Q15 Other congenital malformations of eye	0.001	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
Q37 Cleft palate with cleft lip	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations