TreeWAS – Variant ID: rs682457

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.669	0.331
I25 Chronic ischaemic heart disease	0.000	0.671	0.329
I20 Angina pectoris	0.000	0.684	0.316
I20-I25 Ischaemic heart diseases	0.000	0.687	0.313
I20.9 Angina pectoris, unspecified	0.000	0.688	0.312
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.703	0.297
I22 Subsequent myocardial infarction	0.000	0.709	0.291
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.717	0.283
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.719	0.281
I25.3 Aneurysm of heart	0.000	0.722	0.278
I20.1 Angina pectoris with documented spasm	0.000	0.722	0.278
I25.1 Atherosclerotic heart disease	0.000	0.730	0.270
I25.4 Coronary artery aneurysm	0.000	0.734	0.266
I20.8 Other forms of angina pectoris	0.000	0.748	0.252
I25.6 Silent myocardial ischaemia	0.000	0.764	0.236
I20.0 Unstable angina	0.000	0.766	0.234
I23 Certain current complications following acute myocardial infarction	0.000	0.771	0.229
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.779	0.221
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.821	0.179
I22.8 Subsequent myocardial infarction of other sites	0.000	0.829	0.171
I23.8 Other current complications following acute myocardial infarction	0.000	0.832	0.168
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.836	0.164
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.836	0.164
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.836	0.164
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.836	0.164
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.836	0.164
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.836	0.164
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.836	0.164
I25.2 Old myocardial infarction	0.000	0.840	0.160
I25.5 Ischaemic cardiomyopathy	0.000	0.886	0.114
I24 Other acute ischaemic heart diseases	0.000	0.897	0.103
I21 Acute myocardial infarction	0.000	0.913	0.087
I24.8 Other forms of acute ischaemic heart disease	0.000	0.921	0.079
I21.9 Acute myocardial infarction, unspecified	0.000	0.921	0.079
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.935	0.065
I24.1 Dressler's syndrome	0.000	0.937	0.063
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.937	0.063
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.944	0.056
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.952	0.047
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.959	0.041
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.961	0.039
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.024	0.976	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.020	0.980	0.000
G40 Epilepsy	0.018	0.982	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.016	0.984	0.000
L89.1 Stage II decubitus ulcer	0.000	0.984	0.016
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.014	0.986	0.000
L89 Decubitus ulcer	0.000	0.986	0.014
I21.4 Acute subendocardial myocardial infarction	0.000	0.987	0.013
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.013	0.987	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.013	0.987	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.987	0.013
G40.7 Petit mal, unspecified, without grand mal seizures	0.013	0.987	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.987	0.013
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.0 Traumatic pneumothorax	0.000	0.989	0.011
C34 Malignant neoplasm of bronchus and lung	0.000	0.989	0.011
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.989	0.011
L89.2 Stage III decubitus ulcer	0.000	0.989	0.011
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.989	0.011
C34.9 Bronchus or lung, unspecified	0.000	0.989	0.011
C34.1 Upper lobe, bronchus or lung	0.000	0.989	0.011
S27 Injury of other and unspecified intrathoracic organs	0.000	0.989	0.011
C34.0 Main bronchus	0.000	0.989	0.011
Q61 Cystic kidney disease	0.010	0.990	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.990	0.010
S22.5 Flail chest	0.000	0.990	0.010
S20-S29 Injuries to the thorax	0.000	0.990	0.010
S29.9 Unspecified injury of thorax	0.000	0.990	0.010
G40.8 Other epilepsy	0.010	0.990	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.990	0.010
L89.3 Stage IV decubitus ulcer	0.000	0.990	0.010
S22.3 Fracture of rib	0.000	0.990	0.010
C34.2 Middle lobe, bronchus or lung	0.000	0.990	0.010
S22.4 Multiple fractures of ribs	0.000	0.990	0.010
S29 Other and unspecified injuries of thorax	0.000	0.990	0.010
Q61.0 Congenital single renal cyst	0.010	0.990	0.000
Q61.3 Polycystic kidney, unspecified	0.010	0.990	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.991	0.009
Q63.0 Accessory kidney	0.009	0.991	0.000
S22.50 Flail chest (closed)	0.000	0.991	0.009
C34.3 Lower lobe, bronchus or lung	0.000	0.991	0.009
Q60-Q64 Congenital malformations of the urinary system	0.009	0.991	0.000
S27.3 Other injuries of lung	0.000	0.991	0.009
S22.30 Fracture of rib (closed)	0.000	0.991	0.009
Q61.4 Renal dysplasia	0.009	0.991	0.000
Q63 Other congenital malformations of kidney	0.009	0.991	0.000
S22.2 Fracture of sternum	0.000	0.991	0.009
S22.40 Multiple fractures of ribs (closed)	0.000	0.991	0.009
Q61.2 Polycystic kidney, adult type	0.009	0.991	0.000
I63 Cerebral infarction	0.000	0.992	0.008
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.992	0.008
C34.8 Overlapping lesion of bronchus and lung	0.000	0.992	0.008
S22.9 Fracture of bony thorax, part unspecified	0.000	0.992	0.008
S22.8 Fracture of other parts of bony thorax	0.000	0.992	0.008
I63.9 Cerebral infarction, unspecified	0.000	0.992	0.008
G40.5 Special epileptic syndromes	0.007	0.992	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.992	0.008
S27.8 Injury of other specified intrathoracic organs	0.000	0.992	0.008
S27.7 Multiple injuries of intrathoracic organs	0.000	0.992	0.008
S27.6 Injury of pleura	0.000	0.992	0.008
S27.5 Injury of thoracic trachea	0.000	0.992	0.008
S27.4 Injury of bronchus	0.000	0.992	0.008
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.992	0.008
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.008	0.992	0.000
Q61.9 Cystic kidney disease, unspecified	0.008	0.992	0.000
Q61.8 Other cystic kidney diseases	0.008	0.992	0.000
Q61.1 Polycystic kidney, infantile type	0.008	0.992	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.992	0.008
S27.1 Traumatic haemothorax	0.000	0.992	0.008
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.992	0.008
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.992	0.007
S22.51 Flail chest (open)	0.000	0.992	0.007
I63.8 Other cerebral infarction	0.000	0.992	0.007
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.993	0.007
S26 Injury of heart	0.000	0.993	0.007
S25 Injury of blood vessels of thorax	0.000	0.993	0.007
S24 Injury of nerves and spinal cord at thorax level	0.000	0.993	0.007
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.993	0.007
D22.5 Melanocytic naevi of trunk	0.007	0.993	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.993	0.007
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.993	0.007
S22.31 Fracture of rib (open)	0.000	0.993	0.007
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.993	0.007
Q61.5 Medullary cystic kidney	0.007	0.993	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.993	0.007
S29.7 Multiple injuries of thorax	0.000	0.993	0.007
S29.0 Injury of muscle and tendon at thorax level	0.000	0.993	0.007
S22.0 Fracture of thoracic vertebra	0.000	0.993	0.007
Q62.5 Duplication of ureter	0.007	0.993	0.000
Q64 Other congenital malformations of urinary system	0.007	0.993	0.000
K14.0 Glossitis	0.007	0.993	0.000
S22.20 Fracture of sternum (closed)	0.000	0.993	0.007
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.993	0.007
S21 Open wound of thorax	0.000	0.993	0.006
S29.8 Other specified injuries of thorax	0.000	0.993	0.006
K14.8 Other diseases of tongue	0.007	0.993	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000
S22.21 Fracture of sternum (open)	0.000	0.994	0.006
Q63.9 Congenital malformation of kidney, unspecified	0.006	0.994	0.000
Q63.8 Other specified congenital malformations of kidney	0.006	0.994	0.000
Q63.3 Hyperplastic and giant kidney	0.006	0.994	0.000
Q63.2 Ectopic kidney	0.006	0.994	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.006	0.994	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.994	0.006
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.994	0.006
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.994	0.006
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.994	0.006
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.994	0.006
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.994	0.006
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.994	0.006
K14 Diseases of tongue	0.006	0.994	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.994	0.006
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.994	0.006
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.994	0.006
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.994	0.006
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.994	0.006
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.994	0.006
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.994	0.006
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.006	0.994	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.994	0.006
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
Q62.8 Other congenital malformations of ureter	0.006	0.994	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.006	0.994	0.000
Q62.6 Malposition of ureter	0.006	0.994	0.000
Q62.4 Agenesis of ureter	0.006	0.994	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.006	0.994	0.000
Q62.2 Congenital megaloureter	0.006	0.994	0.000
Q62.1 Atresia and stenosis of ureter	0.006	0.994	0.000
Q62.0 Congenital hydronephrosis	0.006	0.994	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.994	0.006
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.006	0.994	0.000
S20 Superficial injury of thorax	0.000	0.994	0.006
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.994	0.005
S23.4 Sprain and strain of ribs and sternum	0.000	0.994	0.005
S23.3 Sprain and strain of thoracic spine	0.000	0.994	0.005
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.994	0.005
S23.1 Dislocation of thoracic vertebra	0.000	0.994	0.005
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.994	0.005
S24.6 Injury of unspecified nerve of thorax	0.000	0.994	0.005
S24.5 Injury of other nerves of thorax	0.000	0.994	0.005
S24.4 Injury of thoracic sympathetic nerves	0.000	0.994	0.005
S24.3 Injury of peripheral nerves of thorax	0.000	0.994	0.005
S24.2 Injury of nerve root of thoracic spine	0.000	0.994	0.005
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.994	0.005
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.994	0.005
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.994	0.005
S25.8 Injury of other blood vessels of thorax	0.000	0.994	0.005
S25.7 Injury of multiple blood vessels of thorax	0.000	0.994	0.005
S25.5 Injury of intercostal blood vessels	0.000	0.994	0.005
S25.4 Injury of pulmonary blood vessels	0.000	0.994	0.005
S25.3 Injury of innominate or subclavian vein	0.000	0.994	0.005
S25.2 Injury of superior vena cava	0.000	0.994	0.005
S25.1 Injury of innominate or subclavian artery	0.000	0.994	0.005
S25.0 Injury of thoracic aorta	0.000	0.994	0.005
S26.9 Injury of heart, unspecified	0.000	0.994	0.005
S26.8 Other injuries of heart	0.000	0.994	0.005
S26.0 Injury of heart with haemopericardium	0.000	0.994	0.005
S28.1 Traumatic amputation of part of thorax	0.000	0.994	0.005
S28.0 Crushed chest	0.000	0.994	0.005
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.994	0.005
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.994	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.995	0.005
M21.26 Flexion deformity (Lower leg)	0.000	0.995	0.005
Q44.6 Cystic disease of liver	0.005	0.995	0.000
K14.9 Disease of tongue, unspecified	0.005	0.995	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.995	0.005
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
M21.24 Flexion deformity (Hand)	0.000	0.995	0.005
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.995	0.000
Q38.1 Ankyloglossia	0.005	0.995	0.000
R94.5 Abnormal results of liver function studies	0.005	0.995	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.005	0.995	0.000
Q64.8 Other specified congenital malformations of urinary system	0.005	0.995	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.005	0.995	0.000
Q64.6 Congenital diverticulum of bladder	0.005	0.995	0.000
Q64.5 Congenital absence of bladder and urethra	0.005	0.995	0.000
Q64.4 Malformation of urachus	0.005	0.995	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.005	0.995	0.000
Q64.2 Congenital posterior urethral valves	0.005	0.995	0.000
Q64.1 Exstrophy of urinary bladder	0.005	0.995	0.000
Q64.0 Epispadias	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.995	0.005
M21.2 Flexion deformity	0.000	0.995	0.005
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.995	0.005
S21.8 Open wound of other parts of thorax	0.000	0.995	0.005
S21.7 Multiple open wounds of thoracic wall	0.000	0.995	0.005
S21.0 Open wound of breast	0.000	0.995	0.005
Q44.5 Other congenital malformations of bile ducts	0.005	0.995	0.000
Q45 Other congenital malformations of digestive system	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
K91.4 Colostomy and enterostomy malfunction	0.005	0.995	0.000
Q76.0 Spina bifida occulta	0.005	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.005	0.995	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.005	0.995	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q80-Q89 Other congenital malformations	0.005	0.995	0.000
Q38.7 Pharyngeal pouch	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
S21.2 Open wound of back wall of thorax	0.000	0.995	0.005
S21.1 Open wound of front wall of thorax	0.000	0.995	0.005
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
K14.6 Glossodynia	0.005	0.995	0.000
M25.54 Pain in joint (Hand)	0.000	0.995	0.005
F00.9 Dementia in Alzheimer's disease, unspecified	0.005	0.995	0.000
S21.9 Open wound of thorax, part unspecified	0.000	0.995	0.004
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
K14.5 Plicated tongue	0.005	0.995	0.000
K14.4 Atrophy of tongue papillae	0.005	0.995	0.000
K14.3 Hypertrophy of tongue papillae	0.005	0.995	0.000
K14.2 Median rhomboid glossitis	0.005	0.995	0.000
K14.1 Geographic tongue	0.005	0.995	0.000
Q38.8 Other congenital malformations of pharynx	0.004	0.995	0.000
Q38.6 Other congenital malformations of mouth	0.004	0.995	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.004	0.995	0.000
Q38.3 Other congenital malformations of tongue	0.004	0.995	0.000
Q38.2 Macroglossia	0.004	0.995	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.004	0.995	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.995	0.005
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.995	0.000
Q73 Reduction defects of unspecified limb	0.004	0.995	0.000
Q72 Reduction defects of lower limb	0.004	0.995	0.000
Q71 Reduction defects of upper limb	0.004	0.995	0.000
Q70 Syndactyly	0.004	0.995	0.000
Q69 Polydactyly	0.004	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.995	0.000
Q44.7 Other congenital malformations of liver	0.004	0.995	0.000
Q44.4 Choledochal cyst	0.004	0.995	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.004	0.995	0.000
Q44.2 Atresia of bile ducts	0.004	0.995	0.000
Q44.1 Other congenital malformations of gallbladder	0.004	0.995	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.004	0.995	0.000
Q39 Congenital malformations of oesophagus	0.004	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.995	0.000
Q76.7 Congenital malformation of sternum	0.004	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.995	0.000
Q76.5 Cervical rib	0.004	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
I84.4 External haemorrhoids with other complications	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
S20.7 Multiple superficial injuries of thorax	0.000	0.996	0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.004	0.996	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.996	0.004
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.996	0.004
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.996	0.004
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.996	0.004
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.996	0.004
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.996	0.004
N41.1 Chronic prostatitis	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.996	0.004
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
F00 Dementia in Alzheimer's disease	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Q45.8 Other specified congenital malformations of digestive system	0.004	0.996	0.000
S20.4 Other superficial injuries of back wall of thorax	0.000	0.996	0.004
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
D04.2 Skin of ear and external auricular canal	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
S20.1 Other and unspecified superficial injuries of breast	0.000	0.996	0.004
S20.0 Contusion of breast	0.000	0.996	0.004
E11.4 With neurological complications	0.000	0.996	0.004
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.996	0.004
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.996	0.004
M21.29 Flexion deformity (Site unspecified)	0.000	0.996	0.004
M21.28 Flexion deformity (Other)	0.000	0.996	0.004
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.996	0.004
M21.23 Flexion deformity (Forearm)	0.000	0.996	0.004
M21.22 Flexion deformity (Upper arm)	0.000	0.996	0.004
M21.21 Flexion deformity (Shoulder region)	0.000	0.996	0.004
M21.20 Flexion deformity (Multiple sites)	0.000	0.996	0.004
H43.8 Other disorders of vitreous body	0.000	0.996	0.004
K91.2 Postsurgical malabsorption, not elsewhere classified	0.004	0.996	0.000
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.996	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.004	0.996	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.996	0.000
Q45.1 Annular pancreas	0.004	0.996	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.996	0.000
Q74.1 Congenital malformation of knee	0.004	0.996	0.000
D04 Carcinoma in situ of skin	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q83 Congenital malformations of breast	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.996	0.000
Q40.1 Congenital hiatus hernia	0.003	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.996	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.996	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.996	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.996	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.996	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.996	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.996	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.996	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.996	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.996	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.996	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.996	0.000
Q89 Other congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
K91.5 Postcholecystectomy syndrome	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q82 Other congenital malformations of skin	0.004	0.996	0.000
D04.5 Skin of trunk	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.003	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.996	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.996	0.000
Q78.6 Multiple congenital exostoses	0.003	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.996	0.000
Q78.4 Enchondromatosis	0.003	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.996	0.000
Q78.2 Osteopetrosis	0.003	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.996	0.000
S20.2 Contusion of thorax	0.000	0.996	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.004	0.996	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.004	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.996	0.000
S62.50 Fracture of thumb (closed)	0.000	0.996	0.004
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.996	0.000
Q72.7 Split foot	0.003	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.996	0.000
Q75.3 Macrocephaly	0.003	0.996	0.000
Q75.2 Hypertelorism	0.003	0.996	0.000
Q75.1 Craniofacial dysostosis	0.003	0.996	0.000
Q75.0 Craniosynostosis	0.003	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.996	0.000
Q77.5 Diastrophic dysplasia	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.996	0.000
Q77.2 Short rib syndrome	0.003	0.996	0.000
Q77.1 Thanatophoric short stature	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations