TreeWAS – Variant ID: rs6869388

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.0 Amblyopia ex anopsia	0.000	0.989	0.011
D80.1 Nonfamilial hypogammaglobulinaemia	0.010	0.990	0.000
D80 Immunodeficiency with predominantly antibody defects	0.009	0.991	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.008	0.992	0.000
D47.2 Monoclonal gammopathy	0.008	0.992	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.008	0.992	0.000
R90.0 Intracranial space-occupying lesion	0.008	0.992	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.007	0.993	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.007	0.993	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.007	0.993	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.007	0.993	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.007	0.993	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.007	0.993	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.007	0.993	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.007	0.993	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.007	0.993	0.000
D46 Myelodysplastic syndromes	0.007	0.993	0.000
N28.8 Other specified disorders of kidney and ureter	0.006	0.994	0.000
I86.1 Scrotal varices	0.006	0.994	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.006	0.994	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.994	0.006
D37-D48 Neoplasms of uncertain or unknown behaviour	0.006	0.994	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.006	0.994	0.000
S02.60 Fracture of mandible (closed)	0.000	0.994	0.006
D46.2 Refractory anaemia with excess of blasts	0.006	0.994	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.006	0.994	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.006	0.994	0.000
D46.4 Refractory anaemia, unspecified	0.006	0.994	0.000
D46.7 Other myelodysplastic syndromes	0.005	0.994	0.000
O32.1 Maternal care for breech presentation	0.000	0.994	0.006
D37.4 Colon	0.005	0.995	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.005	0.995	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.005	0.995	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.005	0.995	0.000
D37.7 Other digestive organs	0.005	0.995	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.005	0.995	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.005	0.995	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.005	0.995	0.000
D46.1 Refractory anaemia with sideroblasts	0.005	0.995	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.005	0.995	0.000
D37.1 Stomach	0.005	0.995	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.995	0.005
D37.2 Small intestine	0.005	0.995	0.000
D44.7 Aortic body and other paraganglia	0.005	0.995	0.000
D45 Polycythaemia vera	0.005	0.995	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.005	0.995	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.005	0.995	0.000
D47.4 Osteomyelofibrosis	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.995	0.005
D37.0 Lip, oral cavity and pharynx	0.005	0.995	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.005	0.995	0.000
D37.9 Digestive organ, unspecified	0.005	0.995	0.000
D37.3 Appendix	0.004	0.995	0.000
D37.6 Liver, gallbladder and bile ducts	0.004	0.995	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.005	0.995	0.000
D38.5 Other respiratory organs	0.004	0.995	0.000
D48.5 Skin	0.004	0.995	0.000
D44.8 Pluriglandular involvement	0.004	0.996	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.004	0.996	0.000
D44.1 Adrenal gland	0.004	0.996	0.000
D44.6 Carotid body	0.004	0.996	0.000
S02.6 Fracture of mandible	0.000	0.996	0.004
Z35 Supervision of high-risk pregnancy	0.000	0.996	0.004
D44.4 Craniopharyngeal duct	0.004	0.996	0.000
D44.0 Thyroid gland	0.004	0.996	0.000
D38.0 Larynx	0.004	0.996	0.000
D44.9 Endocrine gland, unspecified	0.004	0.996	0.000
D44.5 Pineal gland	0.004	0.996	0.000
D44.2 Parathyroid gland	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.000	0.996	0.004
H33.4 Traction detachment of retina	0.004	0.996	0.000
D38.6 Respiratory organ, unspecified	0.004	0.996	0.000
D38.4 Thymus	0.004	0.996	0.000
D38.3 Mediastinum	0.004	0.996	0.000
D38.2 Pleura	0.004	0.996	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.004	0.996	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.996	0.004
M25.76 Osteophyte (Lower leg)	0.004	0.996	0.000
D43.1 Brain, infratentorial	0.004	0.996	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.004	0.996	0.000
D42.9 Meninges, unspecified	0.003	0.996	0.000
D42.1 Spinal meninges	0.003	0.996	0.000
D42.0 Cerebral meninges	0.003	0.996	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.996	0.000
D43.9 Central nervous system, unspecified	0.003	0.996	0.000
D43.7 Other parts of central nervous system	0.003	0.996	0.000
D43.4 Spinal cord	0.003	0.996	0.000
D43.3 Cranial nerves	0.003	0.996	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.996	0.004
D48.0 Bone and articular cartilage	0.003	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
D48.4 Peritoneum	0.003	0.996	0.000
D48.3 Retroperitoneum	0.003	0.996	0.000
D43.0 Brain, supratentorial	0.003	0.996	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.997	0.003
D39.9 Female genital organ, unspecified	0.003	0.997	0.000
D39.7 Other female genital organs	0.003	0.997	0.000
D39.2 Placenta	0.003	0.997	0.000
D39.0 Uterus	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
S02.61 Fracture of mandible (open)	0.000	0.997	0.003
D38.1 Trachea, bronchus and lung	0.003	0.997	0.000
D44.3 Pituitary gland	0.003	0.997	0.000
D43.2 Brain, unspecified	0.003	0.997	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.997	0.003
Z35.6 Supervision of very young primigravida	0.000	0.997	0.003
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.997	0.003
D84 Other immunodeficiencies	0.003	0.997	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.003	0.997	0.000
D39.1 Ovary	0.003	0.997	0.000
D48.1 Connective and other soft tissue	0.003	0.997	0.000
D40.9 Male genital organ, unspecified	0.003	0.997	0.000
D40.7 Other male genital organs	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
D32.0 Cerebral meninges	0.000	0.997	0.003
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.997	0.003
D40.1 Testis	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D48.7 Other specified sites	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.997	0.003
S02.5 Fracture of tooth	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
S02.31 Fracture of orbital floor (open)	0.000	0.997	0.003
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
D84.1 Defects in the complement system	0.002	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
K50.9 Crohn's disease, unspecified	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
D48.6 Breast	0.002	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.997	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
M77.4 Metatarsalgia	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.998	0.002
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
D37.5 Rectum	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
Q63.0 Accessory kidney	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.000	0.998	0.002
D41.2 Ureter	0.002	0.998	0.000
R94.4 Abnormal results of kidney function studies	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
K35.9 Acute appendicitis, unspecified	0.002	0.998	0.000
M77.49 Metatarsalgia-Site unspec	0.002	0.998	0.000
M77.48 Metatarsalgia-Other	0.002	0.998	0.000
M77.46 Metatarsalgia-Lower Leg	0.002	0.998	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.002	0.998	0.000
M77.44 Metatarsalgia-Hand	0.002	0.998	0.000
M77.43 Metatarsalgia-Forearm	0.002	0.998	0.000
M77.42 Metatarsalgia-Upper arm	0.002	0.998	0.000
M77.41 Metatarsalgia-Shldr region	0.002	0.998	0.000
M77.40 Metatarsalgia-Mult sites	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
X45.0 Home	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.998	0.002
Z94.7 Corneal transplant status	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
N28 Other disorders of kidney and ureter, not elsewhere classified	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
O32.3 Maternal care for face, brow and chin presentation	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.000	0.998	0.002
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.001
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.000	0.998	0.002
O32.4 Maternal care for high head at term	0.000	0.998	0.002
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
H44.2 Degenerative myopia	0.002	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
K82.1 Hydrops of gallbladder	0.000	0.998	0.002
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.001
O32.0 Maternal care for unstable lie	0.000	0.998	0.001
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.998	0.001
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.001
B37.0 Candidal stomatitis	0.002	0.998	0.000
C71.3 Parietal lobe	0.001	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
X45 Accidental poisoning by and exposure to alcohol	0.001	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.001
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
J94.2 Haemothorax	0.001	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.001
C71.2 Temporal lobe	0.001	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.998	0.000
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.001	0.999	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.999	0.001
H54 Blindness and low vision	0.001	0.999	0.000
I46.0 Cardiac arrest with successful resuscitation	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.999	0.001
C83.0 Small cell (diffuse)	0.001	0.999	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
C71.9 Brain, unspecified	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.001	0.999	0.000
R30.9 Painful micturition, unspecified	0.001	0.999	0.000
S06 Intracranial injury	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M79.70 Fibromyalgia (Multiple sites)	0.001	0.999	0.000
C71.7 Brain stem	0.001	0.999	0.000
C71.6 Cerebellum	0.001	0.999	0.000
C71.5 Cerebral ventricle	0.001	0.999	0.000
X45.9 Unspecified place	0.001	0.999	0.000
X45.8 Other specified place	0.001	0.999	0.000
X45.7 Farm	0.001	0.999	0.000
X45.6 Industrial and construction area	0.001	0.999	0.000
X45.5 Trade and service area	0.001	0.999	0.000
X45.4 Street and highway	0.001	0.999	0.000
X45.3 Sports and athletics area	0.001	0.999	0.000
X45.2 School, other institution and public administrative area	0.001	0.999	0.000
X45.1 Residential institution	0.001	0.999	0.000
D41.0 Kidney	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.999	0.001
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
C71.4 Occipital lobe	0.001	0.999	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
M79.19 Myalgia (Site unspecified)	0.001	0.999	0.000
F64.0 Transsexualism	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.999	0.001
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
G59.0 Diabetic mononeuropathy	0.000	0.999	0.001
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.001	0.999	0.000
S06.9 Intracranial injury, unspecified	0.000	0.999	0.001
S61.0 Open wound of finger(s) without damage to nail	0.001	0.999	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.001	0.999	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.001	0.999	0.000
H25.8 Other senile cataract	0.001	0.999	0.000
L73.2 Hidradenitis suppurativa	0.001	0.999	0.000
O62.3 Precipitate labour	0.001	0.999	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
X45.99 Accidental poisoning by and exposure to alcohol; Unspecified place ;During unspecified activity	0.001	0.999	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.999	0.001
S06.7 Intracranial injury with prolonged coma	0.000	0.999	0.001
S06.5 Traumatic subdural haemorrhage	0.000	0.999	0.001
S06.3 Focal brain injury	0.000	0.999	0.001
S06.1 Traumatic cerebral oedema	0.000	0.999	0.001
W55.0 Home	0.001	0.999	0.000
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.999	0.001
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
M94.8 Other specified disorders of cartilage	0.001	0.999	0.000
S06.8 Other intracranial injuries	0.000	0.999	0.001
X49.9 Unspecified place	0.001	0.999	0.000
M79.79 Fibromyalgia (Site unspecified)	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
R94.6 Abnormal results of thyroid function studies	0.001	0.999	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.999	0.001
C69.3 Choroid	0.001	0.999	0.000
N28.0 Ischaemia and infarction of kidney	0.001	0.999	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
W22.9 Unspecified place	0.001	0.999	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.001	0.999	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.999	0.001
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.999	0.001
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.999	0.001
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.999	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.999	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.999	0.001
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.001	0.999	0.000
C71.1 Frontal lobe	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
X41.9 Unspecified place	0.001	0.999	0.000
I86 Varicose veins of other sites	0.001	0.999	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.001	0.999	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.001	0.999	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.001	0.999	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.001	0.999	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.999	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
R73.9 Hyperglycaemia, unspecified	0.001	0.999	0.000
S06.2 Diffuse brain injury	0.000	0.999	0.001
W55.7 Farm	0.001	0.999	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.999	0.001
W55 Bitten or struck by other mammals	0.001	0.999	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
H44.0 Purulent endophthalmitis	0.001	0.999	0.000
N87.1 Moderate cervical dysplasia	0.001	0.999	0.000
Y28.9 Unspecified place	0.001	0.999	0.000
M47.86 Other spondylosis (Lumbar region)	0.001	0.999	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
C45.7 Mesothelioma of other sites	0.000	0.999	0.001
I63.8 Other cerebral infarction	0.000	0.999	0.001
I86.3 Vulval varices	0.001	0.999	0.000
I86.2 Pelvic varices	0.001	0.999	0.000
I86.0 Sublingual varices	0.001	0.999	0.000
K10.8 Other specified diseases of jaws	0.000	0.999	0.001
N28.1 Cyst of kidney, acquired	0.001	0.999	0.000
W06.0 Home	0.000	0.999	0.001
X49.4 Street and highway	0.001	0.999	0.000
X49.0 Home	0.001	0.999	0.000
X49.8 Other specified place	0.001	0.999	0.000
X49.7 Farm	0.001	0.999	0.000
X49.6 Industrial and construction area	0.001	0.999	0.000
X49.5 Trade and service area	0.001	0.999	0.000
X49.3 Sports and athletics area	0.001	0.999	0.000
X49.2 School, other institution and public administrative area	0.001	0.999	0.000
X49.1 Residential institution	0.001	0.999	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.999	0.001
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
H44.8 Other disorders of globe	0.001	0.999	0.000
N42.2 Atrophy of prostate	0.001	0.999	0.000
S06.0 Concussion	0.000	0.999	0.001
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
X41.0 Home	0.001	0.999	0.000
X41.8 Other specified place	0.001	0.999	0.000
X41.7 Farm	0.001	0.999	0.000
X41.6 Industrial and construction area	0.001	0.999	0.000
X41.5 Trade and service area	0.001	0.999	0.000
X41.4 Street and highway	0.001	0.999	0.000
X41.3 Sports and athletics area	0.001	0.999	0.000
X41.2 School, other institution and public administrative area	0.001	0.999	0.000
X41.1 Residential institution	0.001	0.999	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.999	0.001
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.999	0.001
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.999	0.001
C49.4 Connective and soft tissue of abdomen	0.000	0.999	0.001
C83.2 Mixed small and large cell (diffuse)	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.999	0.001
S00.3 Superficial injury of nose	0.000	0.999	0.001
S71.1 Open wound of thigh	0.001	0.999	0.000
W55.9 Unspecified place	0.001	0.999	0.000
W55.5 Trade and service area	0.001	0.999	0.000
W55.6 Industrial and construction area	0.001	0.999	0.000
W55.4 Street and highway	0.001	0.999	0.000
W55.3 Sports and athletics area	0.001	0.999	0.000
W55.2 School, other institution and public administrative area	0.001	0.999	0.000
W55.1 Residential institution	0.001	0.999	0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.999	0.001
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.001	0.999	0.000
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations