TreeWAS – Variant ID: rs6927322

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
L40 Psoriasis	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
L40.9 Psoriasis, unspecified	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.001	0.999
L40-L45 Papulosquamous disorders	0.002	0.998
Chapter XII Diseases of the skin and subcutaneous tissue	0.003	0.997
L40.5 Arthropathic psoriasis	0.009	0.991
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.011	0.989
D50-D53 Nutritional anaemias	0.012	0.988
# Top node	0.012	0.988
D50.9 Iron deficiency anaemia, unspecified	0.012	0.988
D50 Iron deficiency anaemia	0.012	0.988
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.017	0.983
E10-E14 Diabetes mellitus	0.019	0.981
M06 Other rheumatoid arthritis	0.022	0.978
E10 Insulin-dependent diabetes mellitus	0.026	0.974
L00-L08 Infections of the skin and subcutaneous tissue	0.032	0.968
D60-D64 Aplastic and other anaemias	0.037	0.963
E10.9 Without complications	0.042	0.958
M05-M14 Inflammatory polyarthropathies	0.048	0.952
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.055	0.945
L08 Other local infections of skin and subcutaneous tissue	0.060	0.940
D64 Other anaemias	0.063	0.937
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.076	0.924
D64.9 Anaemia, unspecified	0.081	0.919
L57 Skin changes due to chronic exposure to nonionising radiation	0.092	0.908
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.100	0.900
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.102	0.898
C44 Other malignant neoplasms of skin	0.108	0.892
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.114	0.886
C44.3 Skin of other and unspecified parts of face	0.114	0.886
E70-E90 Metabolic disorders	0.116	0.884
E50-E64 Other nutritional deficiencies	0.118	0.882
Chapter I Certain infectious and parasitic diseases	0.130	0.870
C44.1 Skin of eyelid, including canthus	0.132	0.868
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.136	0.864
C44.4 Skin of scalp and neck	0.139	0.861
L02 Cutaneous abscess, furuncle and carbuncle	0.140	0.860
E10.3 With ophthalmic complications	0.141	0.859
E06 Thyroiditis	0.143	0.857
L57.0 Actinic keratosis	0.145	0.855
C44.7 Skin of lower limb, including hip	0.147	0.853
L40.0 Psoriasis vulgaris	0.149	0.850
E89.0 Postprocedural hypothyroidism	0.150	0.850
M07 Psoriatic and enteropathic arthropathies	0.165	0.835
M06.0 Seronegative rheumatoid arthritis	0.171	0.829
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.174	0.826
Chapter VII Diseases of the eye and adnexa	0.184	0.816
B25-B34 Other viral diseases	0.189	0.811
E05 Thyrotoxicosis [hyperthyroidism]	0.190	0.810
E40-E46 Malnutrition	0.190	0.810
L08.8 Other specified local infections of skin and subcutaneous tissue	0.190	0.810
C44.6 Skin of upper limb, including shoulder	0.191	0.809
M05 Seropositive rheumatoid arthritis	0.199	0.801
E86 Volume depletion	0.199	0.801
E04 Other non-toxic goitre	0.206	0.794
B35-B49 Mycoses	0.207	0.793
E53 Deficiency of other B group vitamins	0.208	0.792
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.212	0.788
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.223	0.777
D61 Other aplastic anaemias	0.223	0.777
E14 Unspecified diabetes mellitus	0.226	0.774
Chapter VI Diseases of the nervous system	0.231	0.769
B37 Candidiasis	0.239	0.761
B34 Viral infection of unspecified site	0.240	0.760
L80-L99 Other disorders of the skin and subcutaneous tissue	0.240	0.760
E06.3 Autoimmune thyroiditis	0.245	0.755
M07.3 Other psoriatic arthropathies	0.249	0.751
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.251	0.749
D51 Vitamin B12 deficiency anaemia	0.257	0.743
D55-D59 Haemolytic anaemias	0.260	0.740
H43-H45 Disorders of vitreous body and globe	0.261	0.739
E10.4 With neurological complications	0.265	0.735
E80 Disorders of porphyrin and bilirubin metabolism	0.266	0.734
E10.5 With peripheral circulatory complications	0.267	0.733
G35-G37 Demyelinating diseases of the central nervous system	0.268	0.732
H53-H54 Visual disturbances and blindness	0.270	0.730
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.270	0.729
B37.8 Candidiasis of other sites	0.271	0.729
E53.8 Deficiency of other specified B group vitamins	0.273	0.727
C44.0 Skin of lip	0.273	0.727
H02 Other disorders of eyelid	0.275	0.725
B34.9 Viral infection, unspecified	0.277	0.723
D63 Anaemia in chronic diseases classified elsewhere	0.280	0.720
L40.8 Other psoriasis	0.283	0.717
L40.4 Guttate psoriasis	0.283	0.717
L40.3 Pustulosis palmaris et plantaris	0.283	0.717
L40.2 Acrodermatitis continua	0.283	0.717
L40.1 Generalised pustular psoriasis	0.283	0.717
E03.8 Other specified hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
M06.98 Rheumatoid arthritis, unspecified (Other)	0.284	0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.284	0.716
L44 Other papulosquamous disorders	0.285	0.715
L41 Parapsoriasis	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.285	0.715
L10-L14 Bullous disorders	0.285	0.715
D52 Folate deficiency anaemia	0.289	0.711
M11 Other crystal arthropathies	0.290	0.710
D53 Other nutritional anaemias	0.291	0.708
Chapter XVI Certain conditions originating in the perinatal period	0.292	0.708
D50.1 Sideropenic dysphagia	0.292	0.708
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.292	0.707
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.296	0.704
E12 Malnutrition-related diabetes mellitus	0.296	0.704
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.297	0.703
M00-M03 Infectious arthropathies	0.297	0.703
D70-D77 Other diseases of blood and blood-forming organs	0.298	0.702
E05.0 Thyrotoxicosis with diffuse goitre	0.298	0.702
M06.8 Other specified rheumatoid arthritis	0.299	0.701
M06.4 Inflammatory polyarthropathy	0.299	0.701
M06.2 Rheumatoid bursitis	0.299	0.701
M06.1 Adult-onset Still's disease	0.299	0.701
E10.8 With unspecified complications	0.302	0.698
E10.7 With multiple complications	0.302	0.698
E10.6 With other specified complications	0.302	0.698
E10.2 With renal complications	0.302	0.698
E10.0 With coma	0.302	0.698
A30-A49 Other bacterial diseases	0.302	0.698
G35 Multiple sclerosis	0.302	0.698
E04.2 Non-toxic multinodular goitre	0.303	0.697
L04 Acute lymphadenitis	0.306	0.694
L01 Impetigo	0.306	0.694
L00 Staphylococcal scalded skin syndrome	0.306	0.694
M05.9 Seropositive rheumatoid arthritis, unspecified	0.307	0.693
M07.39 Other psoriatic arthropathies (Site unspecified)	0.309	0.691
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.309	0.691
H02.0 Entropion and trichiasis of eyelid	0.312	0.688
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.316	0.684
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.316	0.684
M12 Other specific arthropathies	0.317	0.683
M09 Juvenile arthritis in diseases classified elsewhere	0.317	0.683
M08 Juvenile arthritis	0.317	0.683
H43 Disorders of vitreous body	0.319	0.681
G30-G32 Other degenerative diseases of the nervous system	0.321	0.679
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.322	0.678
L58 Radiodermatitis	0.322	0.678
L56 Other acute skin changes due to ultraviolet radiation	0.322	0.678
L55 Sunburn	0.322	0.678
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.323	0.677
M14 Arthropathies in other diseases classified elsewhere	0.324	0.675
E46 Unspecified protein-energy malnutrition	0.325	0.674
M06.3 Rheumatoid nodule	0.326	0.674
L08.1 Erythrasma	0.326	0.674
L08.0 Pyoderma	0.326	0.674
D64.8 Other specified anaemias	0.328	0.672
D64.4 Congenital dyserythropoietic anaemia	0.328	0.672
D64.3 Other sideroblastic anaemias	0.328	0.672
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.328	0.672
D64.1 Secondary sideroblastic anaemia due to disease	0.328	0.672
D64.0 Hereditary sideroblastic anaemia	0.328	0.672
H53 Visual disturbances	0.328	0.672
B37.0 Candidal stomatitis	0.329	0.671
E61 Deficiency of other nutrient elements	0.333	0.667
H02.1 Ectropion of eyelid	0.335	0.665
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.336	0.664
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.337	0.663
E10.1 With ketoacidosis	0.340	0.660
A50-A64 Infections with a predominantly sexual mode of transmission	0.340	0.660
E65-E68 Obesity and other hyperalimentation	0.342	0.658
E07 Other disorders of thyroid	0.344	0.656
M65-M68 Disorders of synovium and tendon	0.346	0.654
E13 Other specified diabetes mellitus	0.346	0.653
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.349	0.651
L57.5 Actinic granuloma	0.349	0.651
L57.4 Cutis laxa senilis	0.349	0.651
L57.3 Poikiloderma of Civatte	0.349	0.651
L57.2 Cutis rhomboidalis nuchae	0.349	0.651
L57.1 Actinic reticuloid	0.349	0.651
L81 Other disorders of pigmentation	0.351	0.649
D62 Acute posthaemorrhagic anaemia	0.352	0.648
D61.9 Aplastic anaemia, unspecified	0.356	0.644
G70-G73 Diseases of myoneural junction and muscle	0.356	0.644
L05 Pilonidal cyst	0.360	0.640
C44.8 Overlapping lesion of skin	0.361	0.639
B99-B99 Other infectious diseases	0.361	0.639
E14.9 Without complications	0.362	0.638
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.363	0.637
H02.8 Other specified disorders of eyelid	0.365	0.635
L20-L30 Dermatitis and eczema	0.365	0.635
E84 Cystic fibrosis	0.366	0.634
E79 Disorders of purine and pyrimidine metabolism	0.366	0.634
E77 Disorders of glycoprotein metabolism	0.366	0.634
E76 Disorders of glycosaminoglycan metabolism	0.366	0.634
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.366	0.634
E73 Lactose intolerance	0.366	0.634
E72 Other disorders of amino-acid metabolism	0.366	0.634
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.366	0.634
E70 Disorders of aromatic amino-acid metabolism	0.366	0.634
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.366	0.634
E64 Sequelae of malnutrition and other nutritional deficiencies	0.367	0.632
E63 Other nutritional deficiencies	0.367	0.632
E56 Other vitamin deficiencies	0.367	0.632
E51 Thiamine deficiency	0.367	0.632
E50 Vitamin A deficiency	0.367	0.632
E60 Dietary zinc deficiency	0.367	0.632
E59 Dietary selenium deficiency	0.367	0.632
E58 Dietary calcium deficiency	0.367	0.632
E54 Ascorbic acid deficiency	0.367	0.632
E52 Niacin deficiency [pellagra]	0.367	0.632
B15-B19 Viral hepatitis	0.372	0.628
E88 Other metabolic disorders	0.374	0.626
E80.4 Gilbert's syndrome	0.374	0.626
B25 Cytomegaloviral disease	0.374	0.625
M91-M94 Chondropathies	0.375	0.625
L91 Hypertrophic disorders of skin	0.376	0.624
B85-B89 Pediculosis, acariasis and other infestations	0.376	0.624
B50-B64 Protozoal diseases	0.376	0.624
B20-B24 Human immunodeficiency virus [HIV] disease	0.376	0.624
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.376	0.624
A75-A79 Rickettsioses	0.376	0.624
A70-A74 Other diseases caused by chlamydiae	0.376	0.624
A65-A69 Other spirochaetal diseases	0.376	0.624
A20-A28 Certain zoonotic bacterial diseases	0.376	0.624
A15-A19 Tuberculosis	0.376	0.624
B65-B83 Helminthiases	0.377	0.623
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.377	0.623
M60-M63 Disorders of muscles	0.378	0.621
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.379	0.621
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.380	0.620
E89.8 Other postprocedural endocrine and metabolic disorders	0.380	0.620
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.380	0.620
E89.5 Postprocedural testicular hypofunction	0.380	0.620
E89.4 Postprocedural ovarian failure	0.380	0.620
E89.2 Postprocedural hypoparathyroidism	0.380	0.620
E89.1 Postprocedural hypoinsulinaemia	0.380	0.620
B90-B94 Sequelae of infectious and parasitic diseases	0.381	0.619
E89.3 Postprocedural hypopituitarism	0.382	0.618
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.383	0.617
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.383	0.617
L85 Other epidermal thickening	0.385	0.615
E06.9 Thyroiditis, unspecified	0.385	0.614
E06.5 Other chronic thyroiditis	0.385	0.614
E06.4 Drug-induced thyroiditis	0.385	0.614
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.385	0.614
E06.1 Subacute thyroiditis	0.385	0.614
E06.0 Acute thyroiditis	0.385	0.614
E55 Vitamin D deficiency	0.388	0.612
M45-M49 Spondylopathies	0.388	0.612
B35 Dermatophytosis	0.389	0.611
H53.2 Diplopia	0.390	0.610
E04.1 Non-toxic single thyroid nodule	0.394	0.606
E05.9 Thyrotoxicosis, unspecified	0.396	0.604
L43 Lichen planus	0.397	0.603
H43.3 Other vitreous opacities	0.397	0.603
H05 Disorders of orbit	0.397	0.603
M07.6 Other enteropathic arthropathies	0.401	0.599
M07.5 Arthropathy in ulcerative colitis	0.401	0.599
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.401	0.599
M07.2 Psoriatic spondylitis	0.401	0.599
M07.1 Arthritis mutilans	0.401	0.599
M07.0 Distal interphalangeal psoriatic arthropathy	0.401	0.599
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.402	0.598
H40-H42 Glaucoma	0.403	0.597
M06.08 Seronegative rheumatoid arthritis (Other)	0.405	0.594
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.405	0.594
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.405	0.594
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.405	0.594
M06.04 Seronegative rheumatoid arthritis (Hand)	0.405	0.594
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.405	0.594
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.405	0.594
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.405	0.594
L42 Pityriasis rosea	0.407	0.593
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.410	0.589
D63.8 Anaemia in other chronic diseases classified elsewhere	0.412	0.588
H02.5 Other disorders affecting eyelid function	0.414	0.586
E74 Other disorders of carbohydrate metabolism	0.414	0.586
L81.4 Other melanin hyperpigmentation	0.414	0.586
Chapter XXII Codes for special purposes	0.417	0.582
B33 Other viral diseases, not elsewhere classified	0.418	0.582
B30 Viral conjunctivitis	0.418	0.582
B27 Infectious mononucleosis	0.418	0.582
B26 Mumps	0.418	0.582
E20-E35 Disorders of other endocrine glands	0.418	0.582
E05.5 Thyroid crisis or storm	0.419	0.581
E05.4 Thyrotoxicosis factitia	0.419	0.581
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.419	0.581
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.419	0.581
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.419	0.581
E44 Protein-energy malnutrition of moderate and mild degree	0.419	0.581
E45 Retarded development following protein-energy malnutrition	0.419	0.581
E43 Unspecified severe protein-energy malnutrition	0.419	0.581
E42 Marasmic kwashiorkor	0.419	0.581
E41 Nutritional marasmus	0.419	0.581
E40 Kwashiorkor	0.419	0.581
L50-L54 Urticaria and erythema	0.419	0.581
D80-D89 Certain disorders involving the immune mechanism	0.421	0.579
A80-A89 Viral infections of the central nervous system	0.421	0.579
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.422	0.578
L92 Granulomatous disorders of skin and subcutaneous tissue	0.423	0.577
L83 Acanthosis nigricans	0.425	0.575
D72 Other disorders of white blood cells	0.425	0.575
M05.8 Other seropositive rheumatoid arthritis	0.425	0.575
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.425	0.575
M05.2 Rheumatoid vasculitis	0.425	0.575
M05.1 Rheumatoid lung disease	0.425	0.575
M05.0 Felty's syndrome	0.425	0.575
C44.9 Malignant neoplasm of skin, unspecified	0.425	0.575
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.427	0.572
G70 Myasthenia gravis and other myoneural disorders	0.428	0.572
M95.0 Acquired deformity of nose	0.429	0.571
H01 Other inflammation of eyelid	0.430	0.570
H10-H13 Disorders of conjunctiva	0.431	0.569
E04.8 Other specified non-toxic goitre	0.431	0.569
E04.0 Non-toxic diffuse goitre	0.431	0.569
B48 Other mycoses, not elsewhere classified	0.431	0.569
B47 Mycetoma	0.431	0.569
B46 Zygomycosis	0.431	0.569
B45 Cryptococcosis	0.431	0.569
B43 Chromomycosis and phaeomycotic abscess	0.431	0.569
B42 Sporotrichosis	0.431	0.569
B41 Paracoccidioidomycosis	0.431	0.569
B40 Blastomycosis	0.431	0.569
B39 Histoplasmosis	0.431	0.569
B38 Coccidioidomycosis	0.431	0.569
B36 Other superficial mycoses	0.431	0.569
E53.9 Vitamin B deficiency, unspecified	0.432	0.568
E53.1 Pyridoxine deficiency	0.432	0.568
E53.0 Riboflavin deficiency	0.432	0.568
M45 Ankylosing spondylitis	0.432	0.568
G37 Other demyelinating diseases of central nervous system	0.433	0.567
C44.2 Skin of ear and external auricular canal	0.435	0.565
A41 Other septicaemia	0.437	0.563
D59 Acquired haemolytic anaemia	0.439	0.561
G80-G83 Cerebral palsy and other paralytic syndromes	0.439	0.561
L89 Decubitus ulcer	0.442	0.558
D61.8 Other specified aplastic anaemias	0.443	0.557
D61.3 Idiopathic aplastic anaemia	0.443	0.557
D61.2 Aplastic anaemia due to other external agents	0.443	0.557
D61.1 Drug-induced aplastic anaemia	0.443	0.557
D61.0 Constitutional aplastic anaemia	0.443	0.557
B37.3 Candidiasis of vulva and vagina	0.443	0.556
M10 Gout	0.444	0.556
G30 Alzheimer's disease	0.444	0.556
A46 Erysipelas	0.444	0.556
E14.8 With unspecified complications	0.445	0.555
E14.7 With multiple complications	0.445	0.555
E14.6 With other specified complications	0.445	0.555
E14.5 With peripheral circulatory complications	0.445	0.555
E14.4 With neurological complications	0.445	0.555
E14.2 Withrenal complications	0.445	0.555
E14.1 With ketoacidosis	0.445	0.555
E14.0 With coma	0.445	0.555
G62 Other polyneuropathies	0.449	0.551
H43.1 Vitreous haemorrhage	0.450	0.550
H53.1 Subjective visual disturbances	0.450	0.550
M80-M85 Disorders of bone density and structure	0.451	0.549
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.453	0.547
H55-H59 Other disorders of eye and adnexa	0.454	0.546
B37.7 Candidal septicaemia	0.454	0.545
B37.6 Candidal endocarditis	0.454	0.545
B37.5 Candidal meningitis	0.454	0.545
B37.4 Candidiasis of other urogenital sites	0.454	0.545
B37.2 Candidiasis of skin and nail	0.454	0.545
B37.1 Pulmonary candidiasis	0.454	0.545
L84 Corns and callosities	0.455	0.545
B34.8 Other viral infections of unspecified site	0.455	0.545
B34.4 Papovirus infection, unspecified	0.455	0.545
B34.3 Parvovirus infection, unspecified	0.455	0.545
B34.2 Coronavirus infection, unspecified	0.455	0.545
B34.1 Enterovirus infection, unspecified	0.455	0.545
B34.0 Adenovirus infection, unspecified	0.455	0.545
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.455	0.545
L94 Other localised connective tissue disorders	0.455	0.545
L87 Transepidermal elimination disorders	0.455	0.545
L88 Pyoderma gangrenosum	0.455	0.545
L86 Keratoderma in diseases classified elsewhere	0.455	0.545
L80 Vitiligo	0.455	0.545
D73 Diseases of spleen	0.455	0.544
H44 Disorders of globe	0.456	0.544
E85 Amyloidosis	0.456	0.544
M00 Pyogenic arthritis	0.456	0.544
H46-H48 Disorders of optic nerve and visual pathways	0.458	0.542
M07.38 Other psoriatic arthropathies (Other)	0.461	0.539
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.461	0.539
M07.36 Other psoriatic arthropathies (Lower leg)	0.461	0.539
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.461	0.539
M07.34 Other psoriatic arthropathies (Hand)	0.461	0.539
M07.33 Other psoriatic arthropathies (Forearm)	0.461	0.539
M07.32 Other psoriatic arthropathies (Upper arm)	0.461	0.539
M07.31 Other psoriatic arthropathies (Shoulder region)	0.461	0.539
M07.30 Other psoriatic arthropathies (Multiple sites)	0.461	0.539
H02.6 Xanthelasma of eyelid	0.461	0.539
M11.2 Other chondrocalcinosis	0.463	0.537
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.463	0.537
M45.X9 Ankylosing spondylitis (Site unspecified)	0.464	0.536
H53.9 Visual disturbance, unspecified	0.464	0.536
E14.3 With ophthalmic complications	0.464	0.535
M65 Synovitis and tenosynovitis	0.466	0.534
D51.8 Other vitamin B12 deficiency anaemias	0.467	0.533
D51.3 Other dietary vitamin B12 deficiency anaemia	0.467	0.533
D51.2 Transcobalamin II deficiency	0.467	0.533
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.467	0.533
D75 Other diseases of blood and blood-forming organs	0.467	0.533
A00-A09 Intestinal infectious diseases	0.467	0.532
L03 Cellulitis	0.469	0.531
D58 Other hereditary haemolytic anaemias	0.469	0.530
D57 Sickle-cell disorders	0.469	0.530
D56 Thalassaemia	0.469	0.530
D55 Anaemia due to enzyme disorders	0.469	0.530
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.470	0.530
L93 Lupus erythematosus	0.471	0.529
H30-H36 Disorders of choroid and retina	0.472	0.528
L91.8 Other hypertrophic disorders of skin	0.473	0.527
E80.7 Disorder of bilirubin metabolism, unspecified	0.474	0.526
E80.6 Other disorders of bilirubin metabolism	0.474	0.526
E80.5 Crigler-Najjar syndrome	0.474	0.526
E80.3 Defects of catalase and peroxydase	0.474	0.526
E80.2 Other porphyria	0.474	0.526
E80.1 Porphyria cutanea tarda	0.474	0.526
E80.0 Hereditary erythropoietic porphyria	0.474	0.526
H43.8 Other disorders of vitreous body	0.475	0.525
G36 Other acute disseminated demyelination	0.475	0.525
D50.8 Other iron deficiency anaemias	0.476	0.524
M99 Biomechanical lesions, not elsewhere classified	0.477	0.523
G70.0 Myasthenia gravis	0.480	0.520
H02.7 Other degenerative disorders of eyelid and periocular area	0.480	0.520
H02.2 Lagophthalmos	0.480	0.520
D63.1 Anaemia in other chronic diseases classified elsewhere	0.484	0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.486	0.514
E61.1 Iron deficiency	0.487	0.513
L41.9 Parapsoriasis, unspecified	0.487	0.513
L41.8 Other parapsoriasis	0.487	0.513
L41.5 Retiform parapsoriasis	0.487	0.513
L41.4 Large plaque parapsoriasis	0.487	0.513
L41.3 Small plaque parapsoriasis	0.487	0.513
L41.2 Lymphomatoid papulosis	0.487	0.513
L41.1 Pityriasis lichenoides chronica	0.487	0.513
L41.0 Pityriasis lichenoides et varioliformis acuta	0.487	0.513
L44.9 Papulosquamous disorder, unspecified	0.487	0.513
L44.8 Other specified papulosquamous disorders	0.487	0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.487	0.513
L44.3 Lichen ruber moniliformis	0.487	0.513
L44.2 Lichen striatus	0.487	0.513
L44.1 Lichen nitidus	0.487	0.513
L44.0 Pityriasis rubra pilaris	0.487	0.513
D52.9 Folate deficiency anaemia, unspecified	0.487	0.513
L13 Other bullous disorders	0.487	0.512
L12 Pemphigoid	0.487	0.512
L11 Other acantholytic disorders	0.487	0.512
L10 Pemphigus	0.487	0.512
L14 Bullous disorders in diseases classified elsewhere	0.487	0.512
H04 Disorders of lachrymal system	0.488	0.512
B49 Unspecified mycosis	0.488	0.511
L95 Vasculitis limited to skin, not elsewhere classified	0.489	0.511
E27 Other disorders of adrenal gland	0.489	0.511
D52.8 Other folate deficiency anaemias	0.490	0.510
D52.1 Drug-induced folate deficiency anaemia	0.490	0.510
D52.0 Dietary folate deficiency anaemia	0.490	0.510
H54 Blindness and low vision	0.490	0.510
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.490	0.509
M11.9 Crystal arthropathy, unspecified	0.491	0.509
M11.8 Other specified crystal arthropathies	0.491	0.509
M11.1 Familial chondrocalcinosis	0.491	0.509
M11.0 Hydroxyapatite deposition disease	0.491	0.509
L29 Pruritus	0.491	0.509
D53.9 Nutritional anaemia, unspecified	0.492	0.508
D53.8 Other specified nutritional anaemias	0.492	0.508
D53.2 Scorbutic anaemia	0.492	0.508
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.492	0.508
D53.0 Protein deficiency anaemia	0.492	0.508
P90-P96 Other disorders originating in the perinatal period	0.492	0.508
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.492	0.508
P75-P78 Digestive system disorders of fetus and newborn	0.492	0.508
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.492	0.508
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.492	0.508
P35-P39 Infections specific to the perinatal period	0.492	0.508
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.492	0.508
P10-P15 Birth trauma	0.492	0.508
P05-P08 Disorders related to length of gestation and fetal growth	0.492	0.508
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.492	0.508
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.494	0.506
E12.9 Without complications	0.495	0.504
E12.8 With unspecified complications	0.495	0.504
E12.7 With multiple complications	0.495	0.504
E12.6 With other specified complications	0.495	0.504
E12.5 With peripheral circulatory complications	0.495	0.504
E12.4 With neurological complications	0.495	0.504
E12.3 With ophthalmic complications	0.495	0.504
E12.2 With renal complications	0.495	0.504
E12.1 With ketoacidosis	0.495	0.504

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations