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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6966264
log Bayes Factor = 5.82465
Chromosome 7   position 87,543,037  (GRCh37) Explore rs6966264 on Ensembl!
Variant rs6966264 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.979 0.021 0.000
Chapter IX Diseases of the circulatory system
0.966 0.034 0.000
C15-C26 Malignant neoplasms of digestive organs
0.965 0.035 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
D00-D09 In situ neoplasms
0.946 0.054 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.945 0.055 0.000
C60-C63 Malignant neoplasms of male genital organs
0.938 0.062 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.936 0.064 0.000
G90-G99 Other disorders of the nervous system
0.927 0.073 0.000
I20-I25 Ischaemic heart diseases
0.926 0.074 0.000
M50-M54 Other dorsopathies
0.924 0.076 0.000
R30-R39 Symptoms and signs involving the urinary system
0.923 0.077 0.000
C25 Malignant neoplasm of pancreas
0.917 0.083 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.908 0.092 0.000
E65-E68 Obesity and other hyperalimentation
0.904 0.096 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.896 0.104 0.000
Chapter XX External causes of morbidity and mortality
0.882 0.118 0.000
C61 Malignant neoplasm of prostate
0.879 0.121 0.000
E66 Obesity
0.875 0.125 0.000
Chapter I Certain infectious and parasitic diseases
0.874 0.126 0.000
C50-C50 Malignant neoplasm of breast
0.866 0.134 0.000
I05-I09 Chronic rheumatic heart diseases
0.865 0.135 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.863 0.137 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.856 0.144 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.855 0.145 0.000
M50 Cervical disk disorders
0.853 0.147 0.000
R33 Retention of urine
0.850 0.150 0.000
I21 Acute myocardial infarction
0.850 0.150 0.000
Chapter XI Diseases of the digestive system
0.847 0.153 0.000
M54 Dorsalgia
0.845 0.155 0.000
E66.9 Obesity, unspecified
0.844 0.156 0.000
M45-M49 Spondylopathies
0.844 0.156 0.000
D10-D36 Benign neoplasms
0.837 0.163 0.000
R79 Other abnormal findings of blood chemistry
0.836 0.164 0.000
C44 Other malignant neoplasms of skin
0.828 0.172 0.000
C25.9 Pancreas, unspecified
0.824 0.176 0.000
M50.0 Cervical disk disorder with myelopathy
0.819 0.181 0.000
D04 Carcinoma in situ of skin
0.819 0.181 0.000
C25.0 Head of pancreas
0.819 0.181 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.818 0.182 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.817 0.183 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.812 0.188 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
C20 Malignant neoplasm of rectum
0.810 0.190 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.810 0.190 0.000
C18 Malignant neoplasm of colon
0.807 0.193 0.000
I30-I52 Other forms of heart disease
0.807 0.193 0.000
R73 Elevated blood glucose level
0.805 0.195 0.000
D03 Melanoma in situ
0.805 0.195 0.000
G20-G26 Extrapyramidal and movement disorders
0.800 0.200 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.787 0.213 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.787 0.213 0.000
G93 Other disorders of brain
0.787 0.213 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.786 0.214 0.000
Chapter X Diseases of the respiratory system
0.785 0.215 0.000
E20-E35 Disorders of other endocrine glands
0.784 0.216 0.000
M05-M14 Inflammatory polyarthropathies
0.783 0.216 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.783 0.217 0.000
R30 Pain associated with micturition
0.782 0.218 0.000
I08 Multiple valve diseases
0.782 0.218 0.000
D06 Carcinoma in situ of cervix uteri
0.778 0.222 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.778 0.222 0.000
Chapter XXII Codes for special purposes
0.776 0.223 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.772 0.227 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.772 0.228 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.771 0.229 0.000
C50 Malignant neoplasm of breast
0.770 0.230 0.000
C51-C58 Malignant neoplasms of female genital organs
0.768 0.232 0.000
S00-S09 Injuries to the head
0.767 0.233 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.765 0.235 0.000
Chapter VIII Diseases of the ear and mastoid process
0.762 0.238 0.000
I24 Other acute ischaemic heart diseases
0.761 0.239 0.000
C44.2 Skin of ear and external auricular canal
0.761 0.239 0.000
O36 Maternal care for other known or suspected foetal problems
0.759 0.241 0.000
A30-A49 Other bacterial diseases
0.758 0.242 0.000
M70-M79 Other soft tissue disorders
0.757 0.243 0.000
A00-A09 Intestinal infectious diseases
0.756 0.243 0.000
K90-K93 Other diseases of the digestive system
0.755 0.245 0.000
T93 Sequelae of injuries of lower limb
0.753 0.247 0.000
R25 Abnormal involuntary movements
0.751 0.249 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.749 0.251 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.747 0.253 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.747 0.253 0.000
Chapter VII Diseases of the eye and adnexa
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.745 0.254 0.000
I51 Complications and ill-defined descriptions of heart disease
0.743 0.257 0.000
G95 Other diseases of spinal cord
0.743 0.257 0.000
I20 Angina pectoris
0.740 0.260 0.000
D25 Leiomyoma of uterus
0.738 0.262 0.000
R35 Polyuria
0.738 0.262 0.000
C62 Malignant neoplasm of testis
0.737 0.263 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.736 0.264 0.000
I22 Subsequent myocardial infarction
0.736 0.264 0.000
S50-S59 Injuries to the elbow and forearm
0.733 0.267 0.000
C50.2 Upper-inner quadrant of breast
0.727 0.273 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.726 0.274 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.726 0.274 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.725 0.275 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
R73.9 Hyperglycaemia, unspecified
0.721 0.279 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.721 0.279 0.000
D09 Carcinoma in situ of other and unspecified sites
0.720 0.280 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
K81 Cholecystitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.714 0.286 0.000
M54.3 Sciatica
0.713 0.287 0.000
M65-M68 Disorders of synovium and tendon
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
E00-E07 Disorders of thyroid gland
0.710 0.290 0.000
E66.8 Other obesity
0.709 0.291 0.000
K82 Other diseases of gallbladder
0.708 0.292 0.000
C18.7 Sigmoid colon
0.707 0.293 0.000
T90 Sequelae of injuries of head
0.706 0.294 0.000
E40-E46 Malnutrition
0.705 0.294 0.000
R76 Other abnormal immunological findings in serum
0.705 0.295 0.000
I20.0 Unstable angina
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.702 0.298 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.699 0.301 0.000
R74 Abnormal serum enzyme levels
0.698 0.302 0.000
M13 Other arthritis
0.698 0.302 0.000
D12.4 Descending colon
0.698 0.302 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.697 0.303 0.000
G30-G32 Other degenerative diseases of the nervous system
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.695 0.305 0.000
R39 Other symptoms and signs involving the urinary system
0.693 0.307 0.000
I00-I02 Acute rheumatic fever
0.693 0.307 0.000
G81 Hemiplegia
0.693 0.307 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.692 0.308 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.692 0.308 0.000
C21 Malignant neoplasm of anus and anal canal
0.692 0.308 0.000
C17 Malignant neoplasm of small intestine
0.692 0.308 0.000
C16 Malignant neoplasm of stomach
0.692 0.308 0.000
C23 Malignant neoplasm of gallbladder
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.689 0.311 0.000
M60-M63 Disorders of muscles
0.689 0.311 0.000
M00-M03 Infectious arthropathies
0.689 0.311 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.688 0.311 0.000
M46 Other inflammatory spondylopathies
0.688 0.312 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.688 0.312 0.000
M54.4 Lumbago with sciatica
0.688 0.312 0.000
K81.1 Chronic cholecystitis
0.688 0.312 0.000
K92 Other diseases of digestive system
0.688 0.312 0.000
G96 Other disorders of central nervous system
0.687 0.313 0.000
G70-G73 Diseases of myoneural junction and muscle
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.685 0.315 0.000
V10-V19 Pedal cyclist injured in transport accident
0.685 0.315 0.000
D04.3 Skin of other and unspecified parts of face
0.685 0.315 0.000
G25 Other extrapyramidal and movement disorders
0.685 0.315 0.000
M54.9 Dorsalgia, unspecified
0.685 0.315 0.000
I21.4 Acute subendocardial myocardial infarction
0.684 0.316 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.684 0.316 0.000
M47 Spondylosis
0.684 0.316 0.000
A41 Other septicaemia
0.683 0.317 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.682 0.318 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
T98 Sequelae of other and unspecified effects of external causes
0.680 0.320 0.000
K55-K64 Other diseases of intestines
0.680 0.320 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.679 0.321 0.000
Chapter V Mental and behavioural disorders
0.679 0.321 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.678 0.321 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.678 0.321 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.678 0.321 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.677 0.323 0.000
S60-S69 Injuries to the wrist and hand
0.676 0.324 0.000
K70-K77 Diseases of liver
0.676 0.324 0.000
R25.2 Cramp and spasm
0.676 0.324 0.000
H60-H62 Diseases of external ear
0.675 0.324 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.674 0.326 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.674 0.326 0.000
M40-M43 Deforming dorsopathies
0.673 0.327 0.000
J90-J94 Other diseases of pleura
0.672 0.327 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.672 0.328 0.000
C60 Malignant neoplasm of penis
0.672 0.328 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.672 0.328 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.672 0.328 0.000
H04 Disorders of lachrymal system
0.671 0.329 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.671 0.329 0.000
R77 Other abnormalities of plasma proteins
0.671 0.329 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.671 0.329 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.671 0.329 0.000
R71 Abnormality of red blood cells
0.671 0.329 0.000
C44.4 Skin of scalp and neck
0.671 0.329 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.670 0.330 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.669 0.331 0.000
E70-E90 Metabolic disorders
0.669 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.668 0.332 0.000
I21.9 Acute myocardial infarction, unspecified
0.667 0.333 0.000
I84 Haemorrhoids
0.667 0.333 0.000
M54.1 Radiculopathy
0.667 0.333 0.000
J95-J99 Other diseases of the respiratory system
0.666 0.334 0.000
K82.4 Cholesterolosis of gallbladder
0.666 0.334 0.000
C44.1 Skin of eyelid, including canthus
0.665 0.335 0.000
G93.0 Cerebral cysts
0.665 0.335 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.664 0.336 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G92 Toxic encephalopathy
0.664 0.336 0.000
I23 Certain current complications following acute myocardial infarction
0.664 0.336 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.663 0.337 0.000
D22 Melanocytic naevi
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.663 0.337 0.000
M53 Other dorsopathies, not elsewhere classified
0.663 0.337 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.662 0.338 0.000
G93.6 Cerebral oedema
0.662 0.338 0.000
R36 Urethral discharge
0.662 0.338 0.000
R34 Anuria and oliguria
0.662 0.338 0.000
D04.6 Skin of upper limb, including shoulder
0.662 0.338 0.000
I51.8 Other ill-defined heart diseases
0.662 0.338 0.000
M86-M90 Other osteopathies
0.661 0.339 0.000
R32 Unspecified urinary incontinence
0.661 0.339 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.660 0.340 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.659 0.341 0.000
D12.2 Ascending colon
0.658 0.342 0.000
J00-J06 Acute upper respiratory infections
0.658 0.342 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.657 0.343 0.000
D11 Benign neoplasm of major salivary glands
0.657 0.343 0.000
D06.9 Cervix, unspecified
0.657 0.343 0.000
C25.8 Overlapping lesion of pancreas
0.657 0.343 0.000
C25.7 Other parts of pancreas
0.657 0.343 0.000
C25.4 Endocrine pancreas
0.657 0.343 0.000
C25.3 Pancreatic duct
0.657 0.343 0.000
C25.2 Tail of pancreas
0.657 0.343 0.000
C25.1 Body of pancreas
0.657 0.343 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.657 0.343 0.000
S70-S79 Injuries to the hip and thigh
0.654 0.346 0.000
G91 Hydrocephalus
0.652 0.347 0.000
T92 Sequelae of injuries of upper limb
0.652 0.348 0.000
C44.7 Skin of lower limb, including hip
0.651 0.349 0.000
T33-T35 Frostbite
0.651 0.349 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.651 0.349 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.651 0.349 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.651 0.349 0.000
T00-T07 Injuries involving multiple body regions
0.651 0.349 0.000
S10-S19 Injuries to the neck
0.651 0.349 0.000
E27 Other disorders of adrenal gland
0.651 0.349 0.000
R30.9 Painful micturition, unspecified
0.650 0.350 0.000
I07 Rheumatic tricuspid valve diseases
0.650 0.350 0.000
C77.3 Axillary and upper limb lymph nodes
0.650 0.350 0.000
O36.5 Maternal care for poor foetal growth
0.650 0.350 0.000
C18.9 Colon, unspecified
0.649 0.351 0.000
J09-J18 Influenza and pneumonia
0.649 0.351 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
E67 Other hyperalimentation
0.648 0.352 0.000
E68 Sequelae of hyperalimentation
0.648 0.352 0.000
E65 Localised adiposity
0.648 0.352 0.000
Q80-Q89 Other congenital malformations
0.646 0.354 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.646 0.354 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.646 0.354 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.645 0.355 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.645 0.355 0.000
T93.2 Sequelae of other fractures of lower limb
0.645 0.355 0.000
R47-R49 Symptoms and signs involving speech and voice
0.645 0.355 0.000
D25.9 Leiomyoma of uterus, unspecified
0.644 0.356 0.000
R05 Cough
0.644 0.356 0.000
C79 Secondary malignant neoplasm of other sites
0.642 0.358 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.641 0.359 0.000
S90-S99 Injuries to the ankle and foot
0.640 0.360 0.000
S00 Superficial injury of head
0.638 0.362 0.000
M50.1 Cervical disk disorder with radiculopathy
0.638 0.362 0.000
I44 Atrioventricular and left bundle-branch block
0.638 0.362 0.000
O36.9 Maternal care for foetal problem, unspecified
0.638 0.362 0.000
M13.9 Arthritis, unspecified
0.637 0.363 0.000
S02 Fracture of skull and facial bones
0.637 0.363 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.636 0.364 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.636 0.364 0.000
I24.8 Other forms of acute ischaemic heart disease
0.636 0.364 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.636 0.364 0.000
B35-B49 Mycoses
0.635 0.365 0.000
I84.5 External haemorrhoids without complication
0.635 0.365 0.000
M45 Ankylosing spondylitis
0.634 0.366 0.000
I34 Nonrheumatic mitral valve disorders
0.634 0.366 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.633 0.367 0.000
Y35-Y36 Legal intervention and operations of war
0.633 0.367 0.000
Y10-Y34 Event of undetermined intent
0.633 0.367 0.000
Y00-Y09 Assault
0.633 0.367 0.000
X85-X99 Assault
0.633 0.367 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.633 0.367 0.000
X30-X39 Exposure to forces of nature
0.633 0.367 0.000
X20-X29 Contact with venomous animals and plants
0.633 0.367 0.000
X10-X19 Contact with heat and hot substances
0.633 0.367 0.000
X00-X09 Exposure to smoke, fire and flames
0.633 0.367 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.633 0.367 0.000
W75-W84 Other accidental threats to breathing
0.633 0.367 0.000
W65-W74 Accidental drowning and submersion
0.633 0.367 0.000
W50-W64 Exposure to animate mechanical forces
0.633 0.367 0.000
V98-V99 Other and unspecified transport accidents
0.633 0.367 0.000
V95-V97 Air and space transport accidents
0.633 0.367 0.000
V90-V94 Water transport accidents
0.633 0.367 0.000
V80-V89 Other land transport accidents
0.633 0.367 0.000
V70-V79 Bus occupant injured in transport accident
0.633 0.367 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.633 0.367 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.633 0.367 0.000
V40-V49 Car occupant injured in transport accident
0.633 0.367 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.633 0.367 0.000
V20-V29 Motorcycle rider injured in transport accident
0.633 0.367 0.000
V01-V09 Pedestrian injured in transport accident
0.633 0.367 0.000
I08.8 Other multiple valve diseases
0.633 0.367 0.000
I38 Endocarditis, valve unspecified
0.632 0.368 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.631 0.368 0.000
K35-K38 Diseases of appendix
0.632 0.368 0.000
G83 Other paralytic syndromes
0.631 0.369 0.000
E04 Other non-toxic goitre
0.631 0.369 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.628 0.372 0.000
C44.6 Skin of upper limb, including shoulder
0.628 0.372 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.627 0.373 0.000
E66.1 Drug-induced obesity
0.627 0.373 0.000
E66.0 Obesity due to excess calories
0.627 0.373 0.000
D35.2 Pituitary gland
0.627 0.373 0.000
B99-B99 Other infectious diseases
0.627 0.373 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.627 0.373 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.627 0.373 0.000
B65-B83 Helminthiases
0.627 0.373 0.000
B50-B64 Protozoal diseases
0.627 0.373 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.627 0.373 0.000
B15-B19 Viral hepatitis
0.627 0.373 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.627 0.373 0.000
A75-A79 Rickettsioses
0.627 0.373 0.000
A70-A74 Other diseases caused by chlamydiae
0.627 0.373 0.000
A65-A69 Other spirochaetal diseases
0.627 0.373 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.627 0.373 0.000
A20-A28 Certain zoonotic bacterial diseases
0.627 0.373 0.000
A15-A19 Tuberculosis
0.627 0.373 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.627 0.373 0.000
C77.2 Intra-abdominal lymph nodes
0.626 0.374 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.626 0.374 0.000
D50-D53 Nutritional anaemias
0.625 0.375 0.000
M48 Other spondylopathies
0.624 0.376 0.000
I51.7 Cardiomegaly
0.623 0.377 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.623 0.377 0.000
G37 Other demyelinating diseases of central nervous system
0.622 0.378 0.000
C18.4 Transverse colon
0.622 0.378 0.000
C43 Malignant melanoma of skin
0.622 0.378 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.622 0.378 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.621 0.379 0.000
I09 Other rheumatic heart diseases
0.620 0.380 0.000
I06 Rheumatic aortic valve diseases
0.620 0.380 0.000
I05 Rheumatic mitral valve diseases
0.620 0.380 0.000
M54.39 Sciatica (Site unspecified)
0.619 0.381 0.000
D12.3 Transverse colon
0.619 0.381 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.618 0.381 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.618 0.381 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.618 0.381 0.000
G24 Dystonia
0.618 0.382 0.000
E22 Hyperfunction of pituitary gland
0.617 0.383 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.617 0.383 0.000
K65-K67 Diseases of peritoneum
0.617 0.383 0.000
S06 Intracranial injury
0.616 0.384 0.000
X60-X84 Intentional self-harm
0.616 0.384 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.615 0.385 0.000
D12.7 Rectosigmoid junction
0.615 0.385 0.000
W20-W49 Exposure to inanimate mechanical forces
0.614 0.386 0.000
I45 Other conduction disorders
0.614 0.386 0.000
O85-O92 Complications predominantly related to the puerperium
0.613 0.386 0.000
R30.0 Dysuria
0.613 0.387 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.613 0.387 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.613 0.387 0.000
T95 Sequelae of burns, corrosions and frostbite
0.613 0.387 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.613 0.387 0.000
T91 Sequelae of injuries of neck and trunk
0.613 0.387 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.613 0.387 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.613 0.387 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.613 0.387 0.000
S40-S49 Injuries to the shoulder and upper arm
0.613 0.387 0.000
C50.8 Overlapping lesion of breast
0.612 0.388 0.000
M50.9 Cervical disk disorder, unspecified
0.612 0.388 0.000
M50.8 Other cervical disk disorders
0.612 0.388 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.611 0.389 0.000
I25 Chronic ischaemic heart disease
0.611 0.389 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.611 0.389 0.000
G95.2 Cord compression, unspecified
0.611 0.389 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.610 0.390 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.609 0.390 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.609 0.390 0.000
I82 Other venous embolism and thrombosis
0.609 0.391 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.609 0.391 0.000
R18 Ascites
0.608 0.392 0.000
R45 Symptoms and signs involving emotional state
0.608 0.392 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.608 0.392 0.000
C01 Malignant neoplasm of base of tongue
0.608 0.392 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.607 0.393 0.000
M51 Other intervertebral disk disorders
0.607 0.393 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.607 0.393 0.000
C80 Malignant neoplasm without specification of site
0.606 0.393 0.000
M54.8 Other dorsalgia
0.606 0.394 0.000
M54.6 Pain in thoracic spine
0.606 0.394 0.000
M54.0 Panniculitis affecting regions of neck and back
0.606 0.394 0.000
G93.8 Other specified disorders of brain
0.605 0.395 0.000
M49 Spondylopathies in diseases classified elsewhere
0.605 0.395 0.000
D07.5 Prostate
0.604 0.396 0.000
M07 Psoriatic and enteropathic arthropathies
0.603 0.396 0.000
D10 Benign neoplasm of mouth and pharynx
0.603 0.397 0.000
G81.9 Hemiplegia, unspecified
0.603 0.397 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.602 0.398 0.000
K60 Fissure and fistula of anal and rectal regions
0.602 0.398 0.000
K86 Other diseases of pancreas
0.601 0.398 0.000
I42 Cardiomyopathy
0.600 0.400 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.600 0.400 0.000
D31 Benign neoplasm of eye and adnexa
0.600 0.400 0.000
D30 Benign neoplasm of urinary organs
0.600 0.400 0.000
D29 Benign neoplasm of male genital organs
0.600 0.400 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.600 0.400 0.000
D26 Other benign neoplasms of uterus
0.600 0.400 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.600 0.400 0.000
D19 Benign neoplasm of mesothelial tissue
0.600 0.400 0.000
D16 Benign neoplasm of bone and articular cartilage
0.600 0.400 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.600 0.400 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.600 0.400 0.000
J92 Pleural plaque
0.600 0.400 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.600 0.400 0.000
R79.0 Abnormal level of blood mineral
0.600 0.400 0.000
I50 Heart failure
0.598 0.402 0.000
C09 Malignant neoplasm of tonsil
0.595 0.405 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.595 0.405 0.000
D22.5 Melanocytic naevi of trunk
0.595 0.405 0.000
T66-T78 Other and unspecified effects of external causes
0.594 0.406 0.000
C62.9 Testis, unspecified
0.594 0.406 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.594 0.406 0.000
C44.8 Overlapping lesion of skin
0.594 0.406 0.000
M54.5 Low back pain
0.594 0.406 0.000
R26 Abnormalities of gait and mobility
0.593 0.407 0.000
D32 Benign neoplasm of meninges
0.593 0.407 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.593 0.407 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.592 0.408 0.000
D80-D89 Certain disorders involving the immune mechanism
0.592 0.408 0.000
M79.8 Other specified soft tissue disorders
0.592 0.408 0.000
L20-L30 Dermatitis and eczema
0.592 0.408 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.592 0.408 0.000
O80-O84 Delivery
0.591 0.409 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.590 0.410 0.000
T17 Foreign body in respiratory tract
0.589 0.411 0.000
T18 Foreign body in alimentary tract
0.588 0.412 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.588 0.412 0.000
O36.6 Maternal care for excessive foetal growth
0.587 0.413 0.000
D04.9 Skin, unspecified
0.587 0.413 0.000
D04.8 Skin of other sites
0.587 0.413 0.000
D04.7 Skin of lower limb, including hip
0.587 0.413 0.000
D04.5 Skin of trunk
0.587 0.413 0.000
D04.4 Skin of scalp and neck
0.587 0.413 0.000
D04.2 Skin of ear and external auricular canal
0.587 0.413 0.000
D04.1 Skin of eyelid, including canthus
0.587 0.413 0.000
D04.0 Skin of lip
0.587 0.413 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.587 0.413 0.000
H04.1 Other disorders of lachrymal gland
0.587 0.413 0.000
G82 Paraplegia and tetraplegia
0.586 0.414 0.000
G80 Infantile cerebral palsy
0.586 0.414 0.000
K70 Alcoholic liver disease
0.586 0.414 0.000
D12.9 Anus and anal canal
0.585 0.415 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.583 0.417 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.583 0.417 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.583 0.417 0.000
D27 Benign neoplasm of ovary
0.583 0.417 0.000
H60 Otitis externa
0.582 0.417 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.582 0.418 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.582 0.418 0.000
Q60-Q64 Congenital malformations of the urinary system
0.582 0.418 0.000
Q50-Q56 Congenital malformations of genital organs
0.582 0.418 0.000
Q35-Q37 Cleft lip and cleft palate
0.582 0.418 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.582 0.418 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.582 0.418 0.000
Q00-Q07 Congenital malformations of the nervous system
0.582 0.418 0.000
W00-W19 Falls
0.582 0.418 0.000
D25.1 Intramural leiomyoma of uterus
0.581 0.419 0.000
J98 Other respiratory disorders
0.581 0.419 0.000
Y86 Sequelae of other accidents
0.581 0.419 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.580 0.419 0.000
I60-I69 Cerebrovascular diseases
0.580 0.420 0.000
C18.8 Overlapping lesion of colon
0.579 0.421 0.000
C18.6 Descending colon
0.579 0.421 0.000
C18.5 Splenic flexure
0.579 0.421 0.000
C18.3 Hepatic flexure
0.579 0.421 0.000
C18.1 Appendix
0.579 0.421 0.000
I52 Other heart disorders in diseases classified elsewhere
0.579 0.421 0.000
I48 Atrial fibrillation and flutter
0.579 0.421 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.579 0.421 0.000
I41 Myocarditis in diseases classified elsewhere
0.579 0.421 0.000
I40 Acute myocarditis
0.579 0.421 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.579 0.421 0.000
I37 Pulmonary valve disorders
0.579 0.421 0.000
I36 Nonrheumatic tricuspid valve disorders
0.579 0.421 0.000
I33 Acute and subacute endocarditis
0.579 0.421 0.000
I32 Pericarditis in diseases classified elsewhere
0.579 0.421 0.000
I30 Acute pericarditis
0.579 0.421 0.000
G35 Multiple sclerosis
0.578 0.422 0.000
B25-B34 Other viral diseases
0.578 0.422 0.000
H30-H36 Disorders of choroid and retina
0.578 0.422 0.000
D03.9 Melanoma in situ, unspecified
0.577 0.423 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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