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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs707926
log Bayes Factor = 27.0334
Chromosome 6   position 31,748,820  (GRCh37) Explore rs707926 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
E10.4 With neurological complications
0.996 0.004 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.023 0.977
E10.1 With ketoacidosis
0.970 0.030 0.000
E10.5 With peripheral circulatory complications
0.940 0.060 0.000
E10.2 With renal complications
0.928 0.072 0.000
E10.0 With coma
0.868 0.132 0.000
E10.6 With other specified complications
0.796 0.204 0.000
E10.8 With unspecified complications
0.750 0.250 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10-E14 Diabetes mellitus
0.620 0.380 0.000
E11 Non-insulin-dependent diabetes mellitus
0.535 0.465 0.000
E03 Other hypothyroidism
0.001 0.500 0.499
E11.0 With coma
0.494 0.506 0.000
E11.5 With peripheral circulatory complications
0.470 0.530 0.000
E14 Unspecified diabetes mellitus
0.465 0.535 0.000
E11.4 With neurological complications
0.462 0.538 0.000
E11.6 With other specified complications
0.460 0.540 0.000
E12 Malnutrition-related diabetes mellitus
0.444 0.555 0.000
E13 Other specified diabetes mellitus
0.433 0.566 0.000
E11.1 With ketoacidosis
0.420 0.580 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.591 0.408
E14.6 With other specified complications
0.392 0.608 0.000
E11.7 With multiple complications
0.384 0.616 0.000
E14.8 With unspecified complications
0.369 0.631 0.000
E03.5 Myxoedema coma
0.001 0.641 0.358
E03.4 Atrophy of thyroid (acquired)
0.001 0.641 0.358
E03.3 Postinfectious hypothyroidism
0.001 0.641 0.358
E03.1 Congenital hypothyroidism without goitre
0.001 0.641 0.358
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.641 0.358
E14.4 With neurological complications
0.351 0.649 0.000
E14.1 With ketoacidosis
0.350 0.650 0.000
E14.5 With peripheral circulatory complications
0.348 0.652 0.000
E14.2 Withrenal complications
0.345 0.655 0.000
K50.1 Crohn's disease of large intestine
0.340 0.660 0.000
K50 Crohn's disease [regional enteritis]
0.338 0.662 0.000
K50.9 Crohn's disease, unspecified
0.336 0.664 0.000
E03.8 Other specified hypothyroidism
0.001 0.664 0.335
E14.7 With multiple complications
0.333 0.666 0.000
E14.0 With coma
0.333 0.666 0.000
E11.8 With unspecified complications
0.333 0.667 0.000
E12.9 Without complications
0.319 0.681 0.000
E12.8 With unspecified complications
0.319 0.681 0.000
E12.7 With multiple complications
0.319 0.681 0.000
E12.6 With other specified complications
0.319 0.681 0.000
E12.5 With peripheral circulatory complications
0.319 0.681 0.000
E12.4 With neurological complications
0.319 0.681 0.000
E12.3 With ophthalmic complications
0.319 0.681 0.000
E12.2 With renal complications
0.319 0.681 0.000
E12.1 With ketoacidosis
0.319 0.681 0.000
E12.0 With coma
0.319 0.681 0.000
E13.8 With unspecified complications
0.311 0.689 0.000
E13.7 With multiple complications
0.311 0.689 0.000
E13.6 With other specified complications
0.311 0.689 0.000
E13.5 With peripheral circulatory complications
0.311 0.689 0.000
E13.4 With neurological complications
0.311 0.689 0.000
E13.3 With ophthalmic complications
0.311 0.689 0.000
E13.2 With renal complications
0.311 0.689 0.000
E13.1 With ketoacidosis
0.311 0.689 0.000
E13.0 With coma
0.311 0.689 0.000
K90 Intestinal malabsorption
0.004 0.689 0.306
E13.9 Without complications
0.300 0.700 0.000
K50.8 Other Crohn's disease
0.293 0.707 0.000
E11.2 With renal complications
0.279 0.721 0.000
E14.3 With ophthalmic complications
0.262 0.738 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.002 0.750 0.248
K50-K52 Noninfective enteritis and colitis
0.230 0.770 0.000
K90.3 Pancreatic steatorrhoea
0.003 0.777 0.220
K90.2 Blind loop syndrome, not elsewhere classified
0.003 0.777 0.220
K90.1 Tropical sprue
0.003 0.777 0.220
K50.0 Crohn's disease of small intestine
0.219 0.781 0.000
K52 Other non-infective gastro-enteritis and colitis
0.201 0.799 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.195 0.805 0.000
K90.8 Other intestinal malabsorption
0.004 0.817 0.179
E11.3 With ophthalmic complications
0.180 0.820 0.000
K51 Ulcerative colitis
0.179 0.821 0.000
E14.9 Without complications
0.174 0.826 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.168 0.832 0.000
K90.9 Intestinal malabsorption, unspecified
0.003 0.843 0.154
K51.2 Ulcerative (chronic) proctitis
0.149 0.851 0.000
K51.4 Pseudopolyposis of colon
0.145 0.855 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.145 0.855 0.000
K52.3 Indeterminate colitis
0.143 0.856 0.000
K51.5 Mucosal proctocolitis
0.138 0.861 0.000
K51.9 Ulcerative colitis, unspecified
0.132 0.868 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.132 0.868 0.000
K52.1 Toxic gastro-enteritis and colitis
0.129 0.871 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.129 0.871 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.124 0.876 0.000
J45.9 Asthma, unspecified
0.000 0.925 0.075
D69.6 Thrombocytopenia, unspecified
0.000 0.927 0.073
K51.8 Other ulcerative colitis
0.057 0.943 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.943 0.057
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.950 0.050
E00-E07 Disorders of thyroid gland
0.006 0.954 0.040
D69.5 Secondary thrombocytopenia
0.000 0.956 0.043
D69.0 Allergic purpura
0.000 0.957 0.043
D69.4 Other primary thrombocytopenia
0.000 0.957 0.043
Z48.8 Other specified surgical follow-up care
0.042 0.958 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.959 0.041
D69.2 Other nonthrombocytopenic purpura
0.000 0.959 0.041
D69.1 Qualitative platelet defects
0.000 0.959 0.041
D69.9 Haemorrhagic condition, unspecified
0.000 0.961 0.039
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.004 0.967 0.029
E00 Congenital iodine-deficiency syndrome
0.004 0.967 0.029
E02 Subclinical iodine-deficiency hypothyroidism
0.004 0.967 0.029
K90-K93 Other diseases of the digestive system
0.010 0.971 0.019
J45 Asthma
0.000 0.972 0.028
E07 Other disorders of thyroid
0.006 0.973 0.021
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.003 0.976 0.021
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.003 0.976 0.021
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.003 0.976 0.021
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.003 0.976 0.021
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.003 0.976 0.021
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.003 0.976 0.021
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.003 0.976 0.021
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.003 0.976 0.021
E06 Thyroiditis
0.005 0.976 0.019
Chapter IV Endocrine, nutritional and metabolic diseases
0.009 0.977 0.014
M45.X9 Ankylosing spondylitis (Site unspecified)
0.022 0.978 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.007 0.979 0.014
J45.8 Mixed asthma
0.000 0.980 0.020
J45.1 Nonallergic asthma
0.000 0.980 0.020
E07.8 Other specified disorders of thyroid
0.004 0.980 0.016
E05 Thyrotoxicosis [hyperthyroidism]
0.002 0.980 0.018
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.019 0.980 0.001
E07.1 Dyshormogenetic goitre
0.005 0.980 0.015
E07.0 Hypersecretion of calcitonin
0.005 0.980 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.981 0.019
K91.3 Postoperative intestinal obstruction
0.019 0.981 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.019 0.981 0.000
S00.9 Superficial injury of head, part unspecified
0.000 0.981 0.019
E27 Other disorders of adrenal gland
0.000 0.981 0.019
J45.0 Predominantly allergic asthma
0.000 0.982 0.018
E04 Other non-toxic goitre
0.001 0.982 0.017
S00 Superficial injury of head
0.000 0.982 0.018
S00.1 Contusion of eyelid and periocular area
0.000 0.982 0.018
E06.4 Drug-induced thyroiditis
0.004 0.983 0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.004 0.983 0.014
E06.1 Subacute thyroiditis
0.004 0.983 0.014
E06.0 Acute thyroiditis
0.004 0.983 0.014
E50-E64 Other nutritional deficiencies
0.005 0.983 0.012
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.983 0.017
K91.2 Postsurgical malabsorption, not elsewhere classified
0.016 0.983 0.001
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.983 0.016
K91.4 Colostomy and enterostomy malfunction
0.016 0.983 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.983 0.016
E27.2 Addisonian crisis
0.000 0.984 0.016
S00.7 Multiple superficial injuries of head
0.000 0.984 0.016
E06.3 Autoimmune thyroiditis
0.002 0.984 0.013
E40-E46 Malnutrition
0.007 0.985 0.008
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.005 0.985 0.010
K93.1 Megacolon in Chagas' disease
0.005 0.985 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.005 0.985 0.010
S00.3 Superficial injury of nose
0.000 0.985 0.015
D86.9 Sarcoidosis, unspecified
0.000 0.985 0.015
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.985 0.015
E06.5 Other chronic thyroiditis
0.004 0.985 0.011
E53 Deficiency of other B group vitamins
0.004 0.985 0.011
E04.0 Non-toxic diffuse goitre
0.001 0.985 0.014
D86 Sarcoidosis
0.000 0.985 0.015
E06.9 Thyroiditis, unspecified
0.004 0.986 0.010
E05.5 Thyroid crisis or storm
0.002 0.986 0.013
E05.4 Thyrotoxicosis factitia
0.002 0.986 0.013
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.002 0.986 0.013
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.002 0.986 0.013
K91.5 Postcholecystectomy syndrome
0.013 0.986 0.001
E20 Hypoparathyroidism
0.000 0.986 0.014
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.005 0.986 0.009
E27.5 Adrenomedullary hyperfunction
0.000 0.986 0.013
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.986 0.013
E27.0 Other adrenocortical overactivity
0.000 0.986 0.013
E26 Hyperaldosteronism
0.000 0.986 0.013
E05.8 Other thyrotoxicosis
0.002 0.987 0.012
D86.0 Sarcoidosis of lung
0.000 0.987 0.013
E05.9 Thyrotoxicosis, unspecified
0.000 0.987 0.013
E04.8 Other specified non-toxic goitre
0.001 0.987 0.012
H43.3 Other vitreous opacities
0.013 0.987 0.000
S00.5 Superficial injury of lip and oral cavity
0.000 0.987 0.013
K91.9 Postprocedural disorder of digestive system, unspecified
0.012 0.987 0.001
D80-D89 Certain disorders involving the immune mechanism
0.000 0.987 0.013
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.987 0.013
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.987 0.013
K91.1 Postgastric surgery syndromes
0.012 0.987 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.004 0.987 0.009
E63 Other nutritional deficiencies
0.004 0.987 0.009
E56 Other vitamin deficiencies
0.004 0.987 0.009
E51 Thiamine deficiency
0.004 0.987 0.009
E50 Vitamin A deficiency
0.004 0.987 0.009
E60 Dietary zinc deficiency
0.004 0.987 0.009
E59 Dietary selenium deficiency
0.004 0.987 0.009
E58 Dietary calcium deficiency
0.004 0.987 0.009
E54 Ascorbic acid deficiency
0.004 0.987 0.009
E52 Niacin deficiency [pellagra]
0.004 0.987 0.009
E20.9 Hypoparathyroidism, unspecified
0.000 0.987 0.012
H43 Disorders of vitreous body
0.013 0.987 0.000
S00.0 Superficial injury of scalp
0.000 0.988 0.012
D67 Hereditary factor IX deficiency
0.000 0.988 0.012
H43.8 Other disorders of vitreous body
0.012 0.988 0.000
T78 Adverse effects, not elsewhere classified
0.012 0.988 0.000
E34 Other endocrine disorders
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.000 0.988 0.012
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.988 0.012
E32 Diseases of thymus
0.000 0.988 0.012
E31 Polyglandular dysfunction
0.000 0.988 0.012
E30 Disorders of puberty, not elsewhere classified
0.000 0.988 0.012
E55 Vitamin D deficiency
0.003 0.988 0.009
H43.1 Vitreous haemorrhage
0.012 0.988 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.988 0.012
K91.0 Vomiting following gastro-intestinal surgery
0.011 0.988 0.001
D80 Immunodeficiency with predominantly antibody defects
0.000 0.988 0.012
T78.4 Allergy, unspecified
0.012 0.988 0.000
T78.2 Anaphylactic shock, unspecified
0.012 0.988 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.988 0.012
E27.8 Other specified disorders of adrenal gland
0.000 0.988 0.011
S00.4 Superficial injury of ear
0.000 0.988 0.011
M45 Ankylosing spondylitis
0.012 0.988 0.000
T78.3 Angioneurotic oedema
0.012 0.988 0.000
E26.0 Primary hyperaldosteronism
0.000 0.988 0.011
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.989 0.010
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.989 0.011
E04.9 Non-toxic goitre, unspecified
0.000 0.989 0.011
E29 Testicular dysfunction
0.000 0.989 0.011
E22 Hyperfunction of pituitary gland
0.000 0.989 0.011
E44 Protein-energy malnutrition of moderate and mild degree
0.005 0.989 0.006
E45 Retarded development following protein-energy malnutrition
0.005 0.989 0.006
E43 Unspecified severe protein-energy malnutrition
0.005 0.989 0.006
E42 Marasmic kwashiorkor
0.005 0.989 0.006
E41 Nutritional marasmus
0.005 0.989 0.006
E40 Kwashiorkor
0.005 0.989 0.006
E25 Adrenogenital disorders
0.000 0.989 0.011
D86.3 Sarcoidosis of skin
0.000 0.989 0.011
D86.1 Sarcoidosis of lymph nodes
0.000 0.989 0.011
D66 Hereditary factor VIII deficiency
0.000 0.989 0.011
E53.1 Pyridoxine deficiency
0.003 0.989 0.008
E53.0 Riboflavin deficiency
0.003 0.989 0.008
E21.0 Primary hyperparathyroidism
0.000 0.989 0.011
S00.8 Superficial injury of other parts of head
0.000 0.989 0.011
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.989 0.011
E20.8 Other hypoparathyroidism
0.000 0.990 0.010
E20.1 Pseudohypoparathyroidism
0.000 0.990 0.010
E20.0 Idiopathic hypoparathyroidism
0.000 0.990 0.010
E07.9 Disorder of thyroid, unspecified
0.008 0.990 0.002
E61 Deficiency of other nutrient elements
0.004 0.990 0.006
E15 Nondiabetic hypoglycaemic coma
0.004 0.990 0.006
D84 Other immunodeficiencies
0.000 0.990 0.010
E65-E68 Obesity and other hyperalimentation
0.004 0.990 0.006
E26.9 Hyperaldosteronism, unspecified
0.000 0.990 0.010
E26.8 Other hyperaldosteronism
0.000 0.990 0.010
E26.1 Secondary hyperaldosteronism
0.000 0.990 0.010
T78.0 Anaphylactic shock due to adverse food reaction
0.010 0.990 0.000
Q61 Cystic kidney disease
0.010 0.990 0.000
E28 Ovarian dysfunction
0.000 0.990 0.010
E24 Cushing's syndrome
0.000 0.990 0.010
D86.8 Sarcoidosis of other and combined sites
0.000 0.990 0.010
Q61.0 Congenital single renal cyst
0.010 0.990 0.000
G59.0 Diabetic mononeuropathy
0.010 0.990 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.990 0.010
E34.9 Endocrine disorder, unspecified
0.000 0.990 0.010
E22.1 Hyperprolactinaemia
0.000 0.990 0.010
E46 Unspecified protein-energy malnutrition
0.006 0.990 0.004
E23.0 Hypopituitarism
0.000 0.990 0.009
D83 Common variable immunodeficiency
0.000 0.990 0.009
D82 Immunodeficiency associated with other major defects
0.000 0.990 0.009
D81 Combined immunodeficiencies
0.000 0.990 0.009
K92 Other diseases of digestive system
0.008 0.990 0.002
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.990 0.009
E21.4 Other specified disorders of parathyroid gland
0.000 0.990 0.009
E21.2 Other hyperparathyroidism
0.000 0.990 0.009
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.991 0.008
Q38.7 Pharyngeal pouch
0.009 0.991 0.000
E50.9 Vitamin A deficiency, unspecified
0.003 0.991 0.006
E50.8 Other manifestations of vitamin A deficiency
0.003 0.991 0.006
E50.7 Other ocular manifestations of vitamin A deficiency
0.003 0.991 0.006
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.003 0.991 0.006
E50.5 Vitamin A deficiency with night blindness
0.003 0.991 0.006
E50.4 Vitamin A deficiency with keratomalacia
0.003 0.991 0.006
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.003 0.991 0.006
E50.2 Vitamin A deficiency with corneal xerosis
0.003 0.991 0.006
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.003 0.991 0.006
E50.0 Vitamin A deficiency with conjunctival xerosis
0.003 0.991 0.006
E51.9 Thiamine deficiency, unspecified
0.003 0.991 0.006
E51.8 Other manifestations of thiamine deficiency
0.003 0.991 0.006
E51.2 Wernicke's encephalopathy
0.003 0.991 0.006
E51.1 Beriberi
0.003 0.991 0.006
E56.9 Vitamin deficiency, unspecified
0.003 0.991 0.006
E56.8 Deficiency of other vitamins
0.003 0.991 0.006
E56.1 Deficiency of vitamin K
0.003 0.991 0.006
E56.0 Deficiency of vitamin E
0.003 0.991 0.006
E63.9 Nutritional deficiency, unspecified
0.003 0.991 0.006
E63.8 Other specified nutritional deficiencies
0.003 0.991 0.006
E63.1 Imbalance of constituents of food intake
0.003 0.991 0.006
E63.0 Essential fatty acid [EFA] deficiency
0.003 0.991 0.006
E64.9 Sequelae of unspecified nutritional deficiency
0.003 0.991 0.006
E64.8 Sequelae of other nutritional deficiencies
0.003 0.991 0.006
E64.3 Sequelae of rickets
0.003 0.991 0.006
E64.2 Sequelae of vitamin C deficiency
0.003 0.991 0.006
E64.1 Sequelae of vitamin A deficiency
0.003 0.991 0.006
E64.0 Sequelae of protein-energy malnutrition
0.003 0.991 0.006
T78.8 Other adverse effects, not elsewhere classified
0.009 0.991 0.000
H43.2 Crystalline deposits in vitreous body
0.009 0.991 0.000
H43.0 Vitreous prolapse
0.009 0.991 0.000
E23.2 Diabetes insipidus
0.000 0.991 0.009
M45.X2 Ankylosing spondylitis (Cervical region)
0.009 0.991 0.000
H43.9 Disorder of vitreous body, unspecified
0.009 0.991 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.991 0.009
E34.5 Androgen resistance syndrome
0.000 0.991 0.009
E34.4 Constitutional tall stature
0.000 0.991 0.009
E34.3 Short stature, not elsewhere classified
0.000 0.991 0.009
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.991 0.009
E34.1 Other hypersecretion of intestinal hormones
0.000 0.991 0.009
T78.9 Adverse effect, unspecified
0.009 0.991 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.991 0.009
E30.8 Other disorders of puberty
0.000 0.991 0.009
E30.1 Precocious puberty
0.000 0.991 0.009
E30.0 Delayed puberty
0.000 0.991 0.009
E31.9 Polyglandular dysfunction, unspecified
0.000 0.991 0.009
E31.8 Other polyglandular dysfunction
0.000 0.991 0.009
E31.1 Polyglandular hyperfunction
0.000 0.991 0.009
E31.0 Autoimmune polyglandular failure
0.000 0.991 0.009
E32.9 Disease of thymus, unspecified
0.000 0.991 0.009
E32.8 Other diseases of thymus
0.000 0.991 0.009
E32.1 Abscess of thymus
0.000 0.991 0.009
E32.0 Persistent hyperplasia of thymus
0.000 0.991 0.009
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.991 0.009
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.991 0.009
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.991 0.009
E55.0 Rickets, active
0.002 0.991 0.007
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.009 0.991 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.991 0.009
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.991 0.009
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.991 0.009
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.991 0.009
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.991 0.009
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.991 0.009
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.991 0.009
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.991 0.009
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.991 0.009
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.991 0.009
E53.9 Vitamin B deficiency, unspecified
0.004 0.991 0.005
Q61.3 Polycystic kidney, unspecified
0.009 0.991 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.991 0.008
E23.1 Drug-induced hypopituitarism
0.000 0.991 0.008
Q61.2 Polycystic kidney, adult type
0.009 0.991 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.008 0.991 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.008 0.991 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.008 0.991 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.008 0.991 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.008 0.991 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.008 0.991 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.008 0.991 0.000
L40.9 Psoriasis, unspecified
0.000 0.991 0.009
E34.0 Carcinoid syndrome
0.000 0.991 0.008
E34.8 Other specified endocrine disorders
0.000 0.992 0.008
E29.9 Testicular dysfunction, unspecified
0.000 0.992 0.008
E29.8 Other testicular dysfunction
0.000 0.992 0.008
E29.0 Testicular hyperfunction
0.000 0.992 0.008
T78.1 Other adverse food reactions, not elsewhere classified
0.008 0.992 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.992 0.008
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.992 0.008
E22.8 Other hyperfunction of pituitary gland
0.000 0.992 0.008
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.992 0.008
E44.1 Mild protein-energy malnutrition
0.004 0.992 0.004
E44.0 Moderate protein-energy malnutrition
0.004 0.992 0.004
K92.8 Other specified diseases of digestive system
0.008 0.992 0.001
E25.9 Adrenogenital disorder, unspecified
0.000 0.992 0.008
E25.8 Other adrenogenital disorders
0.000 0.992 0.008
D84.9 Immunodeficiency, unspecified
0.000 0.992 0.008
E55.9 Vitamin D deficiency, unspecified
0.001 0.992 0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.992 0.008
Q61.5 Medullary cystic kidney
0.008 0.992 0.000
Q61.4 Renal dysplasia
0.008 0.992 0.000
K92.9 Disease of digestive system, unspecified
0.008 0.992 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.992 0.008
Q38 Other congenital malformations of tongue, mouth and pharynx
0.008 0.992 0.000
Z48 Other surgical follow-up care
0.008 0.992 0.000
E29.1 Testicular hypofunction
0.000 0.992 0.007
E61.9 Deficiency of nutrient element, unspecified
0.003 0.992 0.004
E61.8 Deficiency of other specified nutrient elements
0.003 0.992 0.004
E61.7 Deficiency of multiple nutrient elements
0.003 0.992 0.004
E61.6 Vanadium deficiency
0.003 0.992 0.004
E61.5 Molybdenum deficiency
0.003 0.992 0.004
E61.4 Chromium deficiency
0.003 0.992 0.004
E61.3 Manganese deficiency
0.003 0.992 0.004
E61.0 Copper deficiency
0.003 0.992 0.004
D84.8 Other specified immunodeficiencies
0.000 0.992 0.007
D84.1 Defects in the complement system
0.000 0.992 0.007
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.992 0.007
E67 Other hyperalimentation
0.003 0.992 0.005
E68 Sequelae of hyperalimentation
0.003 0.992 0.005
Q60-Q64 Congenital malformations of the urinary system
0.008 0.992 0.000
K92.0 Haematemesis
0.007 0.992 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.992 0.007
E24.8 Other Cushing's syndrome
0.000 0.993 0.007
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.993 0.007
E24.3 Ectopic ACTH syndrome
0.000 0.993 0.007
E24.1 Nelson's syndrome
0.000 0.993 0.007
E28.9 Ovarian dysfunction, unspecified
0.000 0.993 0.007
E28.8 Other ovarian dysfunction
0.000 0.993 0.007
E28.1 Androgen excess
0.000 0.993 0.007
E28.0 Oestrogen excess
0.000 0.993 0.007
Q61.8 Other cystic kidney diseases
0.007 0.993 0.000
Q61.1 Polycystic kidney, infantile type
0.007 0.993 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.993 0.007
Q61.9 Cystic kidney disease, unspecified
0.007 0.993 0.000
N95.0 Postmenopausal bleeding
0.007 0.993 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.993 0.007
E61.2 Magnesium deficiency
0.004 0.993 0.004
E28.3 Primary ovarian failure
0.000 0.993 0.007
E16 Other disorders of pancreatic internal secretion
0.003 0.993 0.005
D81.9 Combined immunodeficiency, unspecified
0.000 0.993 0.007
D81.8 Other combined immunodeficiencies
0.000 0.993 0.007
D81.7 Major histocompatibility complex class II deficiency
0.000 0.993 0.007
D81.6 Major histocompatibility complex class I deficiency
0.000 0.993 0.007
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.993 0.007
D81.4 Nezelof's syndrome
0.000 0.993 0.007
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.993 0.007
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.993 0.007
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.993 0.007
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.993 0.007
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.993 0.007
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.993 0.007
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.993 0.007
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.993 0.007
D82.2 Immunodeficiency with short-limbed stature
0.000 0.993 0.007
D82.1 Di George's syndrome
0.000 0.993 0.007
D82.0 Wiskott-Aldrich syndrome
0.000 0.993 0.007
D83.9 Common variable immunodeficiency, unspecified
0.000 0.993 0.007
D83.8 Other common variable immunodeficiencies
0.000 0.993 0.007
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.993 0.007
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.993 0.007
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.993 0.007
E23.6 Other disorders of pituitary gland
0.000 0.993 0.007
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.993 0.007
E65 Localised adiposity
0.003 0.993 0.004
E24.0 Pituitary-dependent Cushing's disease
0.000 0.993 0.006
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.993 0.007
D89.3 Immune reconstitution syndrome
0.000 0.993 0.007
D89.1 Cryoglobulinaemia
0.000 0.993 0.007
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.007 0.993 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.007 0.993 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.993 0.006
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.007 0.993 0.000
E61.1 Iron deficiency
0.003 0.994 0.003
Q20-Q28 Congenital malformations of the circulatory system
0.006 0.994 0.000
Q65 Congenital deformities of hip
0.006 0.994 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.994 0.006
E24.9 Cushing's syndrome, unspecified
0.001 0.994 0.005
Q38.8 Other congenital malformations of pharynx
0.006 0.994 0.000
Q38.6 Other congenital malformations of mouth
0.006 0.994 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.006 0.994 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.006 0.994 0.000
Q38.3 Other congenital malformations of tongue
0.006 0.994 0.000
Q38.2 Macroglossia
0.006 0.994 0.000
Q38.1 Ankyloglossia
0.006 0.994 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.006 0.994 0.000
Q66 Congenital deformities of feet
0.006 0.994 0.000
E67.8 Other specified hyperalimentation
0.002 0.994 0.003
E67.3 Hypervitaminosis D
0.002 0.994 0.003
E67.2 Megavitamin-B6 syndrome
0.002 0.994 0.003
E67.1 Hypercarotenaemia
0.002 0.994 0.003
E67.0 Hypervitaminosis A
0.002 0.994 0.003
Q64 Other congenital malformations of urinary system
0.006 0.994 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.006 0.994 0.000
Q35-Q37 Cleft lip and cleft palate
0.006 0.994 0.000
D55-D59 Haemolytic anaemias
0.000 0.994 0.005
G81.9 Hemiplegia, unspecified
0.000 0.994 0.006
Z48.9 Surgical follow-up care, unspecified
0.005 0.994 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.005 0.994 0.000
E22.0 Acromegaly and pituitary gigantism
0.001 0.995 0.005
Q28 Other congenital malformations of circulatory system
0.005 0.995 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.995 0.005
Q40 Other congenital malformations of upper alimentary tract
0.005 0.995 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.002 0.995 0.003
E16.8 Other specified disorders of pancreatic internal secretion
0.002 0.995 0.003
E16.4 Abnormal secretion of gastrin
0.002 0.995 0.003
E16.3 Increased secretion of glucagon
0.002 0.995 0.003
E16.1 Other hypoglycaemia
0.002 0.995 0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.005 0.995 0.000
Q63 Other congenital malformations of kidney
0.005 0.995 0.000
Q80-Q89 Other congenital malformations
0.005 0.995 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.002 0.995 0.003
Q66.3 Other congenital varus deformities of feet
0.005 0.995 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.005 0.995 0.000
Q74 Other congenital malformations of limb(s)
0.005 0.995 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.005 0.995 0.000
S02.50 Fracture of tooth (closed)
0.000 0.995 0.005
Q65.8 Other congenital deformities of hip
0.005 0.995 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.005 0.995 0.000
Q45 Other congenital malformations of digestive system
0.005 0.995 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.005 0.995 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.005 0.995 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.995 0.005
Q21 Congenital malformations of cardiac septa
0.005 0.995 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.005 0.995 0.000
Q75 Other congenital malformations of skull and face bones
0.005 0.995 0.000
Q73 Reduction defects of unspecified limb
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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