TreeWAS – Variant ID: rs7092236

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
D10-D36 Benign neoplasms	0.998	0.002
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.997	0.003
Z90 Acquired absence of organs, not elsewhere classified	0.996	0.004
C43-C44 Melanoma and other malignant neoplasms of skin	0.994	0.006
N10-N16 Renal tubulo-interstitial diseases	0.991	0.009
C44 Other malignant neoplasms of skin	0.990	0.010
E70-E90 Metabolic disorders	0.988	0.012
E87 Other disorders of fluid, electrolyte and acid-base balance	0.987	0.013
Z90.4 Acquired absence of other parts of digestive tract	0.986	0.014
N40-N51 Diseases of male genital organs	0.985	0.015
N13 Obstructive and reflux uropathy	0.983	0.017
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.983	0.017
E10-E14 Diabetes mellitus	0.983	0.017
N20-N23 Urolithiasis	0.982	0.018
E11 Non-insulin-dependent diabetes mellitus	0.975	0.025
D23 Other benign neoplasms of skin	0.969	0.031
Z93 Artificial opening status	0.968	0.032
K80 Cholelithiasis	0.967	0.033
E11.9 Without complications	0.965	0.035
N20 Calculus of kidney and ureter	0.965	0.035
Z85 Personal history of malignant neoplasm	0.961	0.039
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.961	0.039
Chapter XII Diseases of the skin and subcutaneous tissue	0.959	0.041
K40-K46 Hernia	0.956	0.044
E87.1 Hypo-osmolality and hyponatraemia	0.949	0.051
C44.3 Skin of other and unspecified parts of face	0.944	0.056
K44 Diaphragmatic hernia	0.944	0.056
E65-E68 Obesity and other hyperalimentation	0.940	0.060
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.937	0.063
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.936	0.064
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.935	0.065
N40 Hyperplasia of prostate	0.934	0.066
N13.3 Other and unspecified hydronephrosis	0.933	0.067
K86 Other diseases of pancreas	0.932	0.068
K90-K93 Other diseases of the digestive system	0.931	0.069
Z00-Z13 Persons encountering health services for examination and investigation	0.928	0.072
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.927	0.073
Chapter VII Diseases of the eye and adnexa	0.925	0.075
Chapter XV Pregnancy, childbirth and the puerperium	0.925	0.075
C44.2 Skin of ear and external auricular canal	0.924	0.076
R30-R39 Symptoms and signs involving the urinary system	0.924	0.076
N60-N64 Disorders of breast	0.919	0.081
D22 Melanocytic naevi	0.912	0.088
N20.0 Calculus of kidney	0.909	0.091
Z08 Follow-up examination after treatment for malignant neoplasm	0.909	0.091
E87.5 Hyperkalaemia	0.904	0.095
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.903	0.097
R31 Unspecified haematuria	0.903	0.097
D12.4 Descending colon	0.900	0.100
Z90.2 Acquired absence of lung [part of]	0.899	0.101
L60-L75 Disorders of skin appendages	0.898	0.102
K50-K52 Noninfective enteritis and colitis	0.898	0.102
E66 Obesity	0.897	0.103
N20.1 Calculus of ureter	0.885	0.115
N48 Other disorders of penis	0.883	0.117
Z85.5 Personal history of malignant neoplasm of urinary tract	0.882	0.118
Z93.2 Ileostomy status	0.880	0.120
D12.5 Sigmoid colon	0.879	0.121
E87.2 Acidosis	0.879	0.121
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.878	0.122
K70-K77 Diseases of liver	0.878	0.122
Z83 Family history of other specific disorders	0.872	0.128
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.872	0.128
D23.3 Skin of other and unspecified parts of face	0.872	0.128
Z90.6 Acquired absence of other parts of urinary tract	0.869	0.131
H53-H54 Visual disturbances and blindness	0.868	0.132
L72 Follicular cysts of skin and subcutaneous tissue	0.864	0.136
K20-K31 Diseases of oesophagus, stomach and duodenum	0.864	0.136
K51 Ulcerative colitis	0.864	0.136
L57 Skin changes due to chronic exposure to nonionising radiation	0.864	0.136
N25-N29 Other disorders of kidney and ureter	0.863	0.137
E66.9 Obesity, unspecified	0.859	0.141
K80.2 Calculus of gallbladder without cholecystitis	0.857	0.143
K80.1 Calculus of gallbladder with other cholecystitis	0.853	0.147
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.852	0.148
R10 Abdominal and pelvic pain	0.852	0.148
M20-M25 Other joint disorders	0.850	0.150
K82 Other diseases of gallbladder	0.850	0.150
R10.1 Pain localised to upper abdomen	0.850	0.150
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.849	0.151
D23.7 Skin of lower limb, including hip	0.849	0.151
Chapter V Mental and behavioural disorders	0.847	0.153
K80.8 Other cholelithiasis	0.844	0.156
L72.1 Trichilemmal cyst	0.842	0.158
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.837	0.163
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.836	0.164
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.835	0.165
M80-M85 Disorders of bone density and structure	0.831	0.169
D12.0 Caecum	0.830	0.169
N63 Unspecified lump in breast	0.830	0.170
N13.4 Hydroureter	0.828	0.172
M70-M79 Other soft tissue disorders	0.826	0.174
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.822	0.178
E87.7 Fluid overload	0.822	0.178
E87.3 Alkalosis	0.821	0.179
L57.0 Actinic keratosis	0.820	0.180
K90 Intestinal malabsorption	0.820	0.180
K83 Other diseases of biliary tract	0.819	0.181
C44.7 Skin of lower limb, including hip	0.819	0.181
N60 Benign mammary dysplasia	0.818	0.182
K31 Other diseases of stomach and duodenum	0.818	0.182
D23.5 Skin of trunk	0.817	0.183
K80.0 Calculus of gallbladder with acute cholecystitis	0.816	0.184
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.814	0.186
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.812	0.188
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.811	0.189
K86.8 Other specified diseases of pancreas	0.809	0.191
E11.2 With renal complications	0.809	0.191
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.809	0.191
D12.7 Rectosigmoid junction	0.809	0.191
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.808	0.192
Z90.3 Acquired absence of part of stomach	0.808	0.192
D00-D09 In situ neoplasms	0.805	0.195
K51.9 Ulcerative colitis, unspecified	0.805	0.195
Chapter VIII Diseases of the ear and mastoid process	0.805	0.195
D22.3 Melanocytic naevi of other and unspecified parts of face	0.805	0.195
H53 Visual disturbances	0.804	0.196
K21 Gastro-oesophageal reflux disease	0.804	0.196
N21 Calculus of lower urinary tract	0.800	0.200
K85 Acute pancreatitis	0.799	0.201
Z93.5 Cystostomy status	0.799	0.201
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.798	0.202
N13.5 Kinking and stricture of ureter without hydronephrosis	0.797	0.203
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.796	0.204
O60-O75 Complications of labour and delivery	0.796	0.204
L00-L08 Infections of the skin and subcutaneous tissue	0.795	0.205
C44.1 Skin of eyelid, including canthus	0.792	0.208
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.792	0.208
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.792	0.208
Z88.6 Personal history of allergy to analgesic agent	0.792	0.208
M23 Internal derangement of knee	0.791	0.209
D12.8 Rectum	0.790	0.210
D21 Other benign neoplasms of connective and other soft tissue	0.788	0.212
C15-C26 Malignant neoplasms of digestive organs	0.787	0.213
N47 Redundant prepuce, phimosis and paraphimosis	0.786	0.213
D14 Benign neoplasm of middle ear and respiratory system	0.786	0.214
E87.6 Hypokalaemia	0.783	0.217
E20-E35 Disorders of other endocrine glands	0.782	0.218
N10 Acute tubulo-interstitial nephritis	0.782	0.218
Z93.1 Gastrostomy status	0.779	0.221
N48.8 Other specified disorders of penis	0.777	0.223
D32 Benign neoplasm of meninges	0.777	0.223
K92 Other diseases of digestive system	0.776	0.224
O00-O08 Pregnancy with abortive outcome	0.774	0.226
K20 Oesophagitis	0.774	0.226
N70-N77 Inflammatory diseases of female pelvic organs	0.773	0.227
C44.4 Skin of scalp and neck	0.771	0.229
Z93.6 Other artificial openings of urinary tract status	0.770	0.230
Z85.6 Personal history of leukaemia	0.770	0.230
K31.8 Other specified diseases of stomach and duodenum	0.769	0.231
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.768	0.232
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.768	0.232
N42 Other disorders of prostate	0.768	0.232
Z98 Other postsurgical states	0.766	0.233
Z87 Personal history of other diseases and conditions	0.765	0.235
N13.8 Other obstructive and reflux uropathy	0.765	0.235
N28 Other disorders of kidney and ureter, not elsewhere classified	0.764	0.236
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.764	0.236
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.763	0.237
R10.4 Other and unspecified abdominal pain	0.763	0.237
K46 Unspecified abdominal hernia	0.761	0.239
K65-K67 Diseases of peritoneum	0.760	0.240
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.759	0.241
D11 Benign neoplasm of major salivary glands	0.757	0.243
F30-F39 Mood [affective] disorders	0.755	0.245
M23.2 Derangement of meniscus due to old tear or injury	0.754	0.246
Z91 Personal history of risk-factors, not elsewhere classified	0.753	0.247
C77.1 Intrathoracic lymph nodes	0.753	0.247
K76 Other diseases of liver	0.752	0.248
N20.2 Calculus of kidney with calculus of ureter	0.751	0.249
D22.4 Melanocytic naevi of scalp and neck	0.749	0.251
K86.1 Other chronic pancreatitis	0.746	0.254
E14 Unspecified diabetes mellitus	0.746	0.254
D12.3 Transverse colon	0.745	0.255
K74 Fibrosis and cirrhosis of liver	0.745	0.255
C44.0 Skin of lip	0.745	0.255
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.744	0.256
D23.1 Skin of eyelid, including canthus	0.744	0.256
C78.2 Secondary malignant neoplasm of pleura	0.744	0.256
C43 Malignant melanoma of skin	0.743	0.257
K86.2 Cyst of pancreas	0.742	0.258
M79 Other soft tissue disorders, not elsewhere classified	0.741	0.259
Z83.3 Family history of diabetes mellitus	0.741	0.259
K90.0 Coeliac disease	0.741	0.259
N48.0 Leukoplakia of penis	0.740	0.260
N45 Orchitis and epididymitis	0.739	0.261
Z85.4 Personal history of malignant neoplasm of genital organs	0.739	0.261
Z97 Presence of other devices	0.738	0.262
Z88.4 Personal history of allergy to anaesthetic agent	0.735	0.265
R35 Polyuria	0.734	0.266
E11.4 With neurological complications	0.734	0.266
K86.0 Alcohol-induced chronic pancreatitis	0.733	0.267
R10.2 Pelvic and perineal pain	0.733	0.267
C50-C50 Malignant neoplasm of breast	0.732	0.268
D33 Benign neoplasm of brain and other parts of central nervous system	0.732	0.268
M81 Osteoporosis without pathological fracture	0.731	0.268
Z93.3 Colostomy status	0.731	0.269
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.731	0.269
C79 Secondary malignant neoplasm of other sites	0.730	0.270
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.730	0.270
S00-S09 Injuries to the head	0.728	0.272
R47-R49 Symptoms and signs involving speech and voice	0.727	0.273
D35 Benign neoplasm of other and unspecified endocrine glands	0.726	0.274
H55-H59 Other disorders of eye and adnexa	0.726	0.274
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.726	0.274
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.724	0.276
Z96 Presence of other functional implants	0.723	0.277
O80-O84 Delivery	0.722	0.277
H53.1 Subjective visual disturbances	0.722	0.278
N41 Inflammatory diseases of prostate	0.722	0.278
Z88.5 Personal history of allergy to narcotic agent	0.721	0.279
Z83.7 Family history of diseases of the digestive system	0.720	0.280
H40-H42 Glaucoma	0.719	0.280
Chapter I Certain infectious and parasitic diseases	0.719	0.281
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Z89 Acquired absence of limb	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
Chapter VI Diseases of the nervous system	0.717	0.283
D31 Benign neoplasm of eye and adnexa	0.716	0.284
D30 Benign neoplasm of urinary organs	0.716	0.284
D29 Benign neoplasm of male genital organs	0.716	0.284
D28 Benign neoplasm of other and unspecified female genital organs	0.716	0.284
D26 Other benign neoplasms of uterus	0.716	0.284
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.284
D19 Benign neoplasm of mesothelial tissue	0.716	0.284
D16 Benign neoplasm of bone and articular cartilage	0.716	0.284
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.716	0.284
D10 Benign neoplasm of mouth and pharynx	0.716	0.284
D34 Benign neoplasm of thyroid gland	0.716	0.284
M65-M68 Disorders of synovium and tendon	0.716	0.284
Chapter XX External causes of morbidity and mortality	0.716	0.284
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.715	0.285
D23.4 Skin of scalp and neck	0.715	0.285
Z85.3 Personal history of malignant neoplasm of breast	0.714	0.286
Z90.8 Acquired absence of other organs	0.714	0.286
Z90.0 Acquired absence of part of head and neck	0.714	0.286
C44.5 Skin of trunk	0.713	0.287
R30 Pain associated with micturition	0.713	0.287
D36 Benign neoplasm of other and unspecified sites	0.713	0.287
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.712	0.288
K82.8 Other specified diseases of gallbladder	0.712	0.288
C44.6 Skin of upper limb, including shoulder	0.711	0.289
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.710	0.290
N15 Other renal tubulo-interstitial diseases	0.710	0.290
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.710	0.290
N11 Chronic tubulo-interstitial nephritis	0.710	0.290
C44.9 Malignant neoplasm of skin, unspecified	0.710	0.290
C44.8 Overlapping lesion of skin	0.710	0.290
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.709	0.291
E50-E64 Other nutritional deficiencies	0.709	0.291
E88 Other metabolic disorders	0.709	0.291
E85 Amyloidosis	0.709	0.291
E84 Cystic fibrosis	0.709	0.291
E80 Disorders of porphyrin and bilirubin metabolism	0.709	0.291
E79 Disorders of purine and pyrimidine metabolism	0.709	0.291
E77 Disorders of glycoprotein metabolism	0.709	0.291
E76 Disorders of glycosaminoglycan metabolism	0.709	0.291
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.709	0.291
E74 Other disorders of carbohydrate metabolism	0.709	0.291
E73 Lactose intolerance	0.709	0.291
E72 Other disorders of amino-acid metabolism	0.709	0.291
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.709	0.291
E70 Disorders of aromatic amino-acid metabolism	0.709	0.291
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.709	0.291
K51.2 Ulcerative (chronic) proctitis	0.708	0.292
R93 Abnormal findings on diagnostic imaging of other body structures	0.708	0.292
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.708	0.292
E87.4 Mixed disorder of acid-base balance	0.708	0.292
E87.0 Hyperosmolality and hypernatraemia	0.708	0.292
H54 Blindness and low vision	0.708	0.292
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.708	0.292
N51 Disorders of male genital organs in diseases classified elsewhere	0.706	0.294
N46 Male infertility	0.706	0.294
N44 Torsion of testis	0.706	0.294
N99-N99 Other disorders of the genitourinary system	0.705	0.295
N13.9 Obstructive and reflux uropathy, unspecified	0.705	0.295
N13.7 Vesicoureteral-reflux-associated uropathy	0.705	0.295
N13.6 Pyonephrosis	0.705	0.295
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.705	0.295
C77.2 Intra-abdominal lymph nodes	0.705	0.295
K51.0 Ulcerative (chronic) enterocolitis	0.705	0.295
D12.9 Anus and anal canal	0.705	0.295
D12.1 Appendix	0.705	0.295
E13 Other specified diabetes mellitus	0.705	0.295
E12 Malnutrition-related diabetes mellitus	0.705	0.295
K80.4 Calculus of bile duct with cholecystitis	0.705	0.295
N22 Calculus of urinary tract in diseases classified elsewhere	0.704	0.296
N17-N19 Renal failure	0.704	0.296
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.704	0.296
H52 Disorders of refraction and accommodation	0.704	0.296
L72.0 Epidermal cyst	0.703	0.297
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.702	0.298
E11.8 With unspecified complications	0.699	0.301
E11.7 With multiple complications	0.699	0.301
E11.6 With other specified complications	0.699	0.301
E11.5 With peripheral circulatory complications	0.699	0.301
E11.1 With ketoacidosis	0.699	0.301
E11.0 With coma	0.699	0.301
M25 Other joint disorders, not elsewhere classified	0.699	0.301
D24 Benign neoplasm of breast	0.699	0.301
N60.1 Diffuse cystic mastopathy	0.698	0.302
M79.6 Pain in limb	0.698	0.302
D23.9 Skin, unspecified	0.694	0.305
D23.2 Skin of ear and external auricular canal	0.694	0.305
D23.0 Skin of lip	0.694	0.305
K81 Cholecystitis	0.694	0.306
Z93.9 Artificial opening status, unspecified	0.694	0.306
Z93.8 Other artificial opening status	0.694	0.306
Z93.4 Other artificial openings of gastro-intestinal tract status	0.694	0.306
Z93.0 Tracheostomy status	0.694	0.306
K80.3 Calculus of bile duct with cholangitis	0.693	0.306
H25-H28 Disorders of lens	0.693	0.307
N20.9 Urinary calculus, unspecified	0.692	0.308
E66.8 Other obesity	0.690	0.310
Z82.3 Family history of stroke	0.689	0.310
Z85.0 Personal history of malignant neoplasm of digestive organs	0.689	0.311
Z85.9 Personal history of malignant neoplasm, unspecified	0.689	0.311
R95-R99 Ill-defined and unknown causes of mortality	0.689	0.311
Z11 Special screening examination for infectious and parasitic diseases	0.688	0.311
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.687	0.313
L10-L14 Bullous disorders	0.687	0.313
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.687	0.313
N72 Inflammatory disease of cervix uteri	0.685	0.315
K45 Other abdominal hernia	0.685	0.315
N61 Inflammatory disorders of breast	0.684	0.316
K92.2 Gastro-intestinal haemorrhage, unspecified	0.683	0.317
N23 Unspecified renal colic	0.683	0.317
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.682	0.318
L02 Cutaneous abscess, furuncle and carbuncle	0.682	0.318
R33 Retention of urine	0.680	0.320
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.679	0.321
O70 Perineal laceration during delivery	0.679	0.321
F32 Depressive episode	0.678	0.321
Z90.5 Acquired absence of kidney	0.678	0.322
K42 Umbilical hernia	0.677	0.323
K44.1 Diaphragmatic hernia with gangrene	0.677	0.323
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.677	0.323
D22.6 Melanocytic naevi of upper limb, including shoulder	0.676	0.324
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.674	0.326
E11.3 With ophthalmic complications	0.674	0.326
E67 Other hyperalimentation	0.674	0.326
E68 Sequelae of hyperalimentation	0.674	0.326
E65 Localised adiposity	0.674	0.326
Z87.1 Personal history of diseases of the digestive system	0.673	0.327
C77.0 Lymph nodes of head, face and neck	0.673	0.327
Z87.8 Personal history of other specified conditions	0.673	0.327
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.672	0.328
C76 Malignant neoplasm of other and ill-defined sites	0.672	0.328
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.672	0.328
K83.1 Obstruction of bile duct	0.672	0.328
N00-N08 Glomerular diseases	0.670	0.330
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.670	0.330
M91-M94 Chondropathies	0.670	0.330
M60-M63 Disorders of muscles	0.670	0.330
M00-M03 Infectious arthropathies	0.670	0.330
O20-O29 Other maternal disorders predominantly related to pregnancy	0.670	0.330
N21.0 Calculus in bladder	0.669	0.331
O94-O99 Other obstetric conditions, not elsewhere classified	0.669	0.331
K86.9 Disease of pancreas, unspecified	0.668	0.332
K86.3 Pseudocyst of pancreas	0.668	0.332
K93 Disorders of other digestive organs in diseases classified elsewhere	0.667	0.333
D37-D48 Neoplasms of uncertain or unknown behaviour	0.667	0.333
L50-L54 Urticaria and erythema	0.666	0.334
K82.4 Cholesterolosis of gallbladder	0.666	0.334
S60-S69 Injuries to the wrist and hand	0.666	0.334
Z10 Routine general health check-up of defined subpopulation	0.665	0.335
Z90.1 Acquired absence of breast(s)	0.665	0.335
Z88.7 Personal history of allergy to serum and vaccine	0.665	0.335
Z88.3 Personal history of allergy to other anti-infective agents	0.665	0.335
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.664	0.335
M77 Other enthesopathies	0.664	0.336
H46-H48 Disorders of optic nerve and visual pathways	0.663	0.337
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.663	0.337
H10-H13 Disorders of conjunctiva	0.663	0.337
O85-O92 Complications predominantly related to the puerperium	0.663	0.337
M34 Systemic sclerosis	0.663	0.337
C77.4 Inguinal and lower limb lymph nodes	0.662	0.337
M86-M90 Other osteopathies	0.662	0.338
R36 Urethral discharge	0.662	0.338
R34 Anuria and oliguria	0.662	0.338
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.661	0.339
M05-M14 Inflammatory polyarthropathies	0.661	0.339
M81.9 Osteoporosis, unspecified	0.660	0.340
M22 Disorders of patella	0.660	0.340
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.660	0.340
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.659	0.341
Z96.0 Presence of urogenital implants	0.659	0.341
D22.7 Melanocytic naevi of lower limb, including hip	0.659	0.341
N50 Other disorders of male genital organs	0.658	0.342
Z88.1 Personal history of allergy to other antibiotic agents	0.657	0.343
K85.9 Acute pancreatitis, unspecified	0.657	0.343
R90 Abnormal findings on diagnostic imaging of central nervous system	0.657	0.343
C80 Malignant neoplasm without specification of site	0.657	0.343
Z02 Examination and encounter for administrative purposes	0.657	0.343
K31.9 Disease of stomach and duodenum, unspecified	0.656	0.344
F60-F69 Disorders of adult personality and behaviour	0.655	0.344
N28.1 Cyst of kidney, acquired	0.655	0.345
K25 Gastric ulcer	0.655	0.345
D22.9 Melanocytic naevi, unspecified	0.654	0.346
D22.2 Melanocytic naevi of ear and external auricular canal	0.654	0.346
D22.1 Melanocytic naevi of eyelid, including canthus	0.654	0.346
D22.0 Melanocytic naevi of lip	0.654	0.346
L20-L30 Dermatitis and eczema	0.653	0.346
M72 Fibroblastic disorders	0.653	0.347
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.652	0.348
Z94 Transplanted organ and tissue status	0.651	0.348
Z01.8 Other specified special examinations	0.651	0.349
H53.2 Diplopia	0.651	0.349
N48.1 Balanoposthitis	0.650	0.350
D13.2 Duodenum	0.650	0.350
D22.5 Melanocytic naevi of trunk	0.649	0.351
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.647	0.352
L58 Radiodermatitis	0.647	0.352
L56 Other acute skin changes due to ultraviolet radiation	0.647	0.352
L55 Sunburn	0.647	0.352
C01 Malignant neoplasm of base of tongue	0.647	0.353
Chapter X Diseases of the respiratory system	0.647	0.353
M50-M54 Other dorsopathies	0.646	0.354
N60.3 Fibrosclerosis of breast	0.645	0.355
M80 Osteoporosis with pathological fracture	0.644	0.355
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.644	0.356
L75 Apocrine sweat disorders	0.644	0.356
L74 Eccrine sweat disorders	0.644	0.356
L73 Other follicular disorders	0.644	0.356
L71 Rosacea	0.644	0.356
L70 Acne	0.644	0.356
L68 Hypertrichosis	0.644	0.356
L67 Hair colour and hair shaft abnormalities	0.644	0.356
L66 Cicatricial alopecia [scarring hair loss]	0.644	0.356
L65 Other nonscarring hair loss	0.644	0.356
L64 Androgenic alopecia	0.644	0.356
L63 Alopecia areata	0.644	0.356
L62 Nail disorders in diseases classified elsewhere	0.644	0.356
E66.2 Extreme obesity with alveolar hypoventilation	0.643	0.357
E66.1 Drug-induced obesity	0.643	0.357
E66.0 Obesity due to excess calories	0.643	0.357
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.643	0.357
Z01.5 Diagnostic skin and sensitisation tests	0.642	0.358
Z01.4 Gynaecological examination (general)(routine)	0.641	0.358
K76.6 Portal hypertension	0.641	0.359
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.640	0.360
M23.8 Other internal derangements of knee	0.640	0.360
N28.9 Disorder of kidney and ureter, unspecified	0.639	0.361
S00 Superficial injury of head	0.638	0.362
R39 Other symptoms and signs involving the urinary system	0.638	0.362
D23.6 Skin of upper limb, including shoulder	0.637	0.363
D12.6 Colon, unspecified	0.636	0.364
D07 Carcinoma in situ of other and unspecified genital organs	0.635	0.365
R10.0 Acute abdomen	0.635	0.365
D09 Carcinoma in situ of other and unspecified sites	0.634	0.366
Z03 Medical observation and evaluation for suspected diseases and conditions	0.634	0.366
D14.0 Middle ear, nasal cavity and accessory sinuses	0.634	0.366
H80-H83 Diseases of inner ear	0.634	0.366
N48.9 Disorder of penis, unspecified	0.633	0.367
N48.5 Ulcer of penis	0.633	0.367
N48.4 Impotence of organic origin	0.633	0.367
N48.3 Priapism	0.633	0.367
N48.2 Other inflammatory disorders of penis	0.633	0.367
N60.8 Other benign mammary dysplasias	0.633	0.367
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.632	0.368
O04 Medical abortion	0.631	0.368
S20-S29 Injuries to the thorax	0.631	0.369
D18 Haemangioma and lymphangioma, any site	0.631	0.369
K83.0 Cholangitis	0.631	0.369
R20 Disturbances of skin sensation	0.629	0.371
R94 Abnormal results of function studies	0.629	0.371
K77 Liver disorders in diseases classified elsewhere	0.629	0.371
K75 Other inflammatory liver diseases	0.629	0.371
K73 Chronic hepatitis, not elsewhere classified	0.629	0.371
K72 Hepatic failure, not elsewhere classified	0.629	0.371
K71 Toxic liver disease	0.629	0.371
G35-G37 Demyelinating diseases of the central nervous system	0.628	0.372
Z04 Examination and observation for other reasons	0.626	0.373
Z88.2 Personal history of allergy to sulphonamides	0.626	0.374
Z83.6 Family history of diseases of the respiratory system	0.625	0.375
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.625	0.375
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.625	0.375
Z83.1 Family history of other infectious and parasitic diseases	0.625	0.375
Z83.0 Family history of human immunodeficiency virus [HIV]	0.625	0.375
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.625	0.375
Z98.2 Presence of cerebrospinal fluid drainage device	0.625	0.375
F32.9 Depressive episode, unspecified	0.624	0.376
C09 Malignant neoplasm of tonsil	0.623	0.377
D13.1 Stomach	0.622	0.378
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations