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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs71617099
log Bayes Factor = 17.4399
Chromosome 4   position 180,918,453  (GRCh37) Explore rs71617099 on Ensembl!
Variant rs71617099 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F41 Other anxiety disorders
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
1.000 0.000 0.000
F41.2 Mixed anxiety and depressive disorder
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
F41.9 Anxiety disorder, unspecified
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
F30-F39 Mood [affective] disorders
0.990 0.010 0.000
F10.1 Harmful use
0.988 0.012 0.000
N40-N51 Diseases of male genital organs
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
N30-N39 Other diseases of urinary system
0.983 0.017 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.980 0.020 0.000
E83 Disorders of mineral metabolism
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.974 0.026 0.000
E86 Volume depletion
0.968 0.032 0.000
N32 Other disorders of bladder
0.967 0.033 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.965 0.035 0.000
I60-I69 Cerebrovascular diseases
0.961 0.039 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.957 0.043 0.000
N40 Hyperplasia of prostate
0.956 0.044 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.956 0.044 0.000
F32 Depressive episode
0.954 0.046 0.000
Chapter XI Diseases of the digestive system
0.952 0.048 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.951 0.049 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.949 0.051 0.000
G30-G32 Other degenerative diseases of the nervous system
0.946 0.054 0.000
N32.0 Bladder-neck obstruction
0.943 0.057 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.942 0.058 0.000
M45-M49 Spondylopathies
0.941 0.059 0.000
G90-G99 Other disorders of the nervous system
0.939 0.061 0.000
K82 Other diseases of gallbladder
0.938 0.062 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.937 0.063 0.000
K85 Acute pancreatitis
0.931 0.069 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.927 0.073 0.000
I69 Sequelae of cerebrovascular disease
0.926 0.074 0.000
I67 Other cerebrovascular diseases
0.923 0.077 0.000
Chapter XXII Codes for special purposes
0.921 0.079 0.000
R94 Abnormal results of function studies
0.917 0.083 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.917 0.083 0.000
E83.4 Disorders of magnesium metabolism
0.916 0.084 0.000
K82.8 Other specified diseases of gallbladder
0.916 0.084 0.000
F10.2 Dependence syndrome
0.916 0.084 0.000
F31 Bipolar affective disorder
0.914 0.086 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.912 0.088 0.000
K85.9 Acute pancreatitis, unspecified
0.911 0.089 0.000
I95 Hypotension
0.909 0.091 0.000
E83.1 Disorders of iron metabolism
0.908 0.092 0.000
K70-K77 Diseases of liver
0.902 0.098 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.899 0.101 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.897 0.103 0.000
Chapter XX External causes of morbidity and mortality
0.894 0.106 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.889 0.111 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.887 0.113 0.000
R20 Disturbances of skin sensation
0.885 0.115 0.000
F32.9 Depressive episode, unspecified
0.883 0.117 0.000
I67.9 Cerebrovascular disease, unspecified
0.883 0.117 0.000
R47-R49 Symptoms and signs involving speech and voice
0.880 0.120 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.879 0.121 0.000
M15-M19 Arthrosis
0.877 0.123 0.000
E20-E35 Disorders of other endocrine glands
0.874 0.126 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.874 0.126 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.873 0.127 0.000
I95.1 Orthostatic hypotension
0.871 0.129 0.000
M47 Spondylosis
0.871 0.129 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.866 0.134 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.865 0.135 0.000
R41.0 Disorientation, unspecified
0.865 0.135 0.000
R20.2 Paraesthesia of skin
0.864 0.136 0.000
F10.3 Withdrawal state
0.861 0.139 0.000
I20-I25 Ischaemic heart diseases
0.860 0.140 0.000
G93 Other disorders of brain
0.858 0.142 0.000
R94.5 Abnormal results of liver function studies
0.856 0.144 0.000
K80 Cholelithiasis
0.856 0.144 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.852 0.148 0.000
N32.3 Diverticulum of bladder
0.847 0.153 0.000
K70 Alcoholic liver disease
0.845 0.155 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.845 0.155 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.843 0.157 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.843 0.157 0.000
R25 Abnormal involuntary movements
0.842 0.158 0.000
I25 Chronic ischaemic heart disease
0.838 0.162 0.000
F99-F99 Unspecified mental disorder
0.837 0.163 0.000
G81 Hemiplegia
0.836 0.164 0.000
E83.5 Disorders of calcium metabolism
0.835 0.165 0.000
N48 Other disorders of penis
0.834 0.166 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.833 0.167 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.832 0.168 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.832 0.168 0.000
N25-N29 Other disorders of kidney and ureter
0.832 0.168 0.000
N50 Other disorders of male genital organs
0.831 0.169 0.000
E10-E14 Diabetes mellitus
0.831 0.169 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.831 0.169 0.000
R12 Heartburn
0.828 0.172 0.000
I69.3 Sequelae of cerebral infarction
0.827 0.173 0.000
K82.4 Cholesterolosis of gallbladder
0.827 0.173 0.000
N30 Cystitis
0.822 0.178 0.000
G91 Hydrocephalus
0.820 0.180 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.819 0.181 0.000
N00-N08 Glomerular diseases
0.819 0.181 0.000
I67.2 Cerebral atherosclerosis
0.816 0.184 0.000
R10 Abdominal and pelvic pain
0.813 0.187 0.000
F10.0 Acute intoxication
0.813 0.187 0.000
G30 Alzheimer's disease
0.811 0.189 0.000
N36 Other disorders of urethra
0.810 0.189 0.000
N34 Urethritis and urethral syndrome
0.805 0.195 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.805 0.195 0.000
F31.9 Bipolar affective disorder, unspecified
0.804 0.196 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.804 0.196 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.803 0.197 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.801 0.199 0.000
N99-N99 Other disorders of the genitourinary system
0.801 0.199 0.000
S80-S89 Injuries to the knee and lower leg
0.798 0.201 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.798 0.202 0.000
F00 Dementia in Alzheimer's disease
0.796 0.204 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.795 0.205 0.000
G81.9 Hemiplegia, unspecified
0.791 0.209 0.000
M86-M90 Other osteopathies
0.790 0.210 0.000
M40-M43 Deforming dorsopathies
0.789 0.211 0.000
M20-M25 Other joint disorders
0.787 0.213 0.000
R50-R69 General symptoms and signs
0.787 0.213 0.000
F33 Recurrent depressive disorder
0.786 0.214 0.000
R29.6 Tendency to fall, not elsewhere classified
0.786 0.214 0.000
K12 Stomatitis and related lesions
0.786 0.214 0.000
Chapter VIII Diseases of the ear and mastoid process
0.785 0.215 0.000
K14 Diseases of tongue
0.784 0.216 0.000
I63 Cerebral infarction
0.783 0.217 0.000
R10.2 Pelvic and perineal pain
0.783 0.217 0.000
M48 Other spondylopathies
0.783 0.217 0.000
N32.8 Other specified disorders of bladder
0.782 0.218 0.000
F32.0 Mild depressive episode
0.780 0.220 0.000
M50-M54 Other dorsopathies
0.779 0.221 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.776 0.224 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.774 0.226 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.774 0.226 0.000
M47.2 Other spondylosis with radiculopathy
0.772 0.228 0.000
M91-M94 Chondropathies
0.772 0.228 0.000
R21 Rash and other nonspecific skin eruption
0.771 0.229 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.770 0.230 0.000
R47 Speech disturbances, not elsewhere classified
0.770 0.230 0.000
E11 Non-insulin-dependent diabetes mellitus
0.769 0.231 0.000
F05.9 Delirium, unspecified
0.766 0.234 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
U80 Agent resistant to penicillin and related antibiotics
0.763 0.237 0.000
K85.1 Biliary acute pancreatitis
0.762 0.238 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.761 0.239 0.000
E27 Other disorders of adrenal gland
0.759 0.241 0.000
I95.2 Hypotension due to drugs
0.757 0.242 0.000
F01 Vascular dementia
0.757 0.243 0.000
G31.2 Degeneration of nervous system due to alcohol
0.757 0.243 0.000
F80-F89 Disorders of psychological development
0.756 0.244 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.756 0.244 0.000
F60-F69 Disorders of adult personality and behaviour
0.753 0.247 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.751 0.248 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.751 0.249 0.000
R10.1 Pain localised to upper abdomen
0.750 0.250 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.750 0.250 0.000
M47.8 Other spondylosis
0.749 0.251 0.000
O42 Premature rupture of membranes
0.748 0.252 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.747 0.253 0.000
R27 Other lack of coordination
0.743 0.257 0.000
R53 Malaise and fatigue
0.743 0.257 0.000
S82 Fracture of lower leg, including ankle
0.739 0.261 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.738 0.262 0.000
Chapter X Diseases of the respiratory system
0.737 0.263 0.000
E40-E46 Malnutrition
0.737 0.263 0.000
K72 Hepatic failure, not elsewhere classified
0.736 0.263 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.736 0.264 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
G91.9 Hydrocephalus, unspecified
0.734 0.266 0.000
M16 Coxarthrosis [arthrosis of hip]
0.734 0.266 0.000
G31.0 Circumscribed brain atrophy
0.733 0.267 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.733 0.267 0.000
Y57 Other and unspecified drugs and medicaments
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.731 0.269 0.000
R94.4 Abnormal results of kidney function studies
0.730 0.270 0.000
M19 Other arthrosis
0.730 0.270 0.000
K50-K52 Noninfective enteritis and colitis
0.729 0.271 0.000
M46 Other inflammatory spondylopathies
0.729 0.271 0.000
F10.4 Withdrawal state with delirium
0.726 0.274 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.726 0.274 0.000
N48.8 Other specified disorders of penis
0.726 0.274 0.000
R41.3 Other amnesia
0.725 0.275 0.000
E11.4 With neurological complications
0.725 0.275 0.000
F42 Obsessive-compulsive disorder
0.725 0.275 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.725 0.275 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.724 0.275 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.724 0.276 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.724 0.276 0.000
G93.9 Disorder of brain, unspecified
0.723 0.277 0.000
G90 Disorders of autonomic nervous system
0.722 0.278 0.000
N41 Inflammatory diseases of prostate
0.721 0.279 0.000
R47.8 Other and unspecified speech disturbances
0.721 0.279 0.000
S60-S69 Injuries to the wrist and hand
0.720 0.280 0.000
F99 Mental disorder, not otherwise specified
0.720 0.280 0.000
O32.1 Maternal care for breech presentation
0.719 0.281 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.718 0.282 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F41.8 Other specified anxiety disorders
0.717 0.283 0.000
F41.3 Other mixed anxiety disorders
0.717 0.283 0.000
F41.1 Generalised anxiety disorder
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
F48 Other neurotic disorders
0.717 0.283 0.000
F44 Dissociative [conversion] disorders
0.717 0.283 0.000
R94.3 Abnormal results of cardiovascular function studies
0.716 0.284 0.000
N32.1 Vesicointestinal fistula
0.716 0.284 0.000
G30.9 Alzheimer's disease, unspecified
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.714 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.714 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.714 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.714 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.714 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.714 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F10.6 Amnesic syndrome
0.714 0.286 0.000
F10.5 Psychotic disorder
0.714 0.286 0.000
K75 Other inflammatory liver diseases
0.712 0.288 0.000
K04 Diseases of pulp and periapical tissues
0.712 0.288 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.711 0.289 0.000
E85 Amyloidosis
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E73 Lactose intolerance
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
K82.1 Hydrops of gallbladder
0.710 0.289 0.000
S40-S49 Injuries to the shoulder and upper arm
0.710 0.290 0.000
F38 Other mood [affective] disorders
0.710 0.290 0.000
F34 Persistent mood [affective] disorders
0.710 0.290 0.000
F30 Manic episode
0.710 0.290 0.000
F39 Unspecified mood [affective] disorder
0.710 0.290 0.000
R18 Ascites
0.710 0.290 0.000
K14.0 Glossitis
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.709 0.291 0.000
E87.6 Hypokalaemia
0.709 0.291 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
R42 Dizziness and giddiness
0.708 0.292 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.708 0.292 0.000
N46 Male infertility
0.708 0.292 0.000
N44 Torsion of testis
0.708 0.292 0.000
R23 Other skin changes
0.708 0.292 0.000
R44.3 Hallucinations, unspecified
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
N37 Urethral disorders in diseases classified elsewhere
0.705 0.295 0.000
N33 Bladder disorders in diseases classified elsewhere
0.705 0.295 0.000
R25.3 Fasciculation
0.705 0.295 0.000
K01 Embedded and impacted teeth
0.704 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
R46 Symptoms and signs involving appearance and behaviour
0.702 0.298 0.000
R43 Disturbances of smell and taste
0.702 0.298 0.000
K09 Cysts of oral region, not elsewhere classified
0.702 0.298 0.000
K70.9 Alcoholic liver disease, unspecified
0.702 0.298 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.701 0.299 0.000
E83.8 Other disorders of mineral metabolism
0.701 0.299 0.000
E83.2 Disorders of zinc metabolism
0.701 0.299 0.000
E83.0 Disorders of copper metabolism
0.701 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.700 0.300 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.700 0.300 0.000
Y43 Primarily systemic agents
0.699 0.301 0.000
I00-I02 Acute rheumatic fever
0.699 0.301 0.000
Q80-Q89 Other congenital malformations
0.698 0.302 0.000
K12.1 Other forms of stomatitis
0.698 0.302 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.696 0.304 0.000
Y45.0 Opioids and related analgesics
0.694 0.306 0.000
N32.4 Rupture of bladder, nontraumatic
0.693 0.307 0.000
N32.2 Vesical fistula, not elsewhere classified
0.693 0.307 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.693 0.307 0.000
S50-S59 Injuries to the elbow and forearm
0.693 0.307 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.692 0.308 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.692 0.308 0.000
M16.9 Coxarthrosis, unspecified
0.692 0.308 0.000
O40 Polyhydramnios
0.691 0.309 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.691 0.309 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.690 0.309 0.000
O48 Prolonged pregnancy
0.690 0.310 0.000
M45 Ankylosing spondylitis
0.689 0.311 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.311 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
R63 Symptoms and signs concerning food and fluid intake
0.688 0.312 0.000
E28 Ovarian dysfunction
0.688 0.312 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.686 0.314 0.000
R41.2 Retrograde amnesia
0.685 0.315 0.000
R41.1 Anterograde amnesia
0.685 0.315 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.685 0.315 0.000
R49 Voice disturbances
0.685 0.315 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.684 0.316 0.000
F32.8 Other depressive episodes
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.683 0.316 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.684 0.316 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.682 0.318 0.000
F02 Dementia in other diseases classified elsewhere
0.682 0.318 0.000
F09 Unspecified organic or symptomatic mental disorder
0.682 0.318 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.682 0.318 0.000
K73 Chronic hepatitis, not elsewhere classified
0.682 0.318 0.000
K70.4 Alcoholic hepatic failure
0.681 0.319 0.000
R45 Symptoms and signs involving emotional state
0.681 0.319 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.681 0.319 0.000
K70.0 Alcoholic fatty liver
0.681 0.319 0.000
I62 Other nontraumatic intracranial haemorrhage
0.680 0.319 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.680 0.320 0.000
I61 Intracerebral haemorrhage
0.680 0.320 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.679 0.321 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.679 0.321 0.000
G93.6 Cerebral oedema
0.679 0.321 0.000
N03 Chronic nephritic syndrome
0.679 0.321 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.678 0.322 0.000
N34.2 Other urethritis
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.678 0.322 0.000
R52 Pain, not elsewhere classified
0.677 0.323 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.677 0.323 0.000
V80-V89 Other land transport accidents
0.676 0.324 0.000
R40 Somnolence, stupor and coma
0.675 0.325 0.000
M19.0 Primary arthrosis of other joints
0.675 0.325 0.000
K70.1 Alcoholic hepatitis
0.675 0.325 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.325 0.000
I95.9 Hypotension, unspecified
0.675 0.325 0.000
Q60-Q64 Congenital malformations of the urinary system
0.674 0.326 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.674 0.326 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.673 0.327 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.673 0.327 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.673 0.327 0.000
G92 Toxic encephalopathy
0.673 0.327 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.673 0.327 0.000
M43 Other deforming dorsopathies
0.673 0.327 0.000
K82.9 Disease of gallbladder, unspecified
0.672 0.327 0.000
K82.3 Fistula of gallbladder
0.672 0.327 0.000
K82.2 Perforation of gallbladder
0.672 0.327 0.000
K82.0 Obstruction of gallbladder
0.672 0.327 0.000
M31 Other necrotising vasculopathies
0.672 0.328 0.000
I67.8 Other specified cerebrovascular diseases
0.672 0.328 0.000
T79-T79 Certain early complications of trauma
0.671 0.328 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.671 0.328 0.000
I99 Other and unspecified disorders of circulatory system
0.671 0.328 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.328 0.000
M17 Gonarthrosis [arthrosis of knee]
0.670 0.330 0.000
N50.1 Vascular disorders of male genital organs
0.670 0.330 0.000
W00-W19 Falls
0.670 0.330 0.000
U80.1 Methicillin resistant agent
0.669 0.331 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.669 0.331 0.000
E80.4 Gilbert's syndrome
0.668 0.332 0.000
W50-W64 Exposure to animate mechanical forces
0.668 0.332 0.000
N50.8 Other specified disorders of male genital organs
0.668 0.332 0.000
O41 Other disorders of amniotic fluid and membranes
0.668 0.332 0.000
K85.8 Other acute pancreatitis
0.668 0.332 0.000
K85.3 Drug-induced acute pancreatitis
0.668 0.332 0.000
K85.2 Alcohol-induced acute pancreatitis
0.668 0.332 0.000
K85.0 Idiopathic acute pancreatitis
0.668 0.332 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
G93.3 Postviral fatigue syndrome
0.666 0.334 0.000
N30.3 Trigonitis
0.665 0.335 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.664 0.336 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.664 0.336 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.664 0.336 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.664 0.336 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.664 0.336 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.664 0.336 0.000
M35 Other systemic involvement of connective tissue
0.664 0.336 0.000
R60 Oedema, not elsewhere classified
0.663 0.337 0.000
E88 Other metabolic disorders
0.663 0.337 0.000
I25.3 Aneurysm of heart
0.662 0.338 0.000
F45 Somatoform disorders
0.662 0.338 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.662 0.338 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.662 0.338 0.000
I67.5 Moyamoya disease
0.662 0.338 0.000
I67.4 Hypertensive encephalopathy
0.662 0.338 0.000
I67.3 Progressive vascular leukoencephalopathy
0.662 0.338 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.662 0.338 0.000
G31.8 Other specified degenerative diseases of nervous system
0.662 0.338 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.661 0.339 0.000
F40 Phobic anxiety disorders
0.660 0.340 0.000
Y40 Systemic antibiotics
0.660 0.340 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.659 0.341 0.000
R25.1 Tremor, unspecified
0.659 0.341 0.000
G80 Infantile cerebral palsy
0.658 0.341 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.658 0.342 0.000
R94.7 Abnormal results of other endocrine function studies
0.658 0.342 0.000
R94.6 Abnormal results of thyroid function studies
0.658 0.342 0.000
R94.2 Abnormal results of pulmonary function studies
0.658 0.342 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.658 0.342 0.000
R94.0 Abnormal results of function studies of central nervous system
0.658 0.342 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.658 0.342 0.000
T33-T35 Frostbite
0.657 0.342 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.657 0.342 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.657 0.342 0.000
T00-T07 Injuries involving multiple body regions
0.657 0.342 0.000
N30.8 Other cystitis
0.657 0.343 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.656 0.344 0.000
S10-S19 Injuries to the neck
0.656 0.344 0.000
N17-N19 Renal failure
0.655 0.345 0.000
F31.8 Other bipolar affective disorders
0.655 0.345 0.000
F31.7 Bipolar affective disorder, currently in remission
0.655 0.345 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.655 0.345 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.655 0.345 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.655 0.345 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.655 0.345 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.655 0.345 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.654 0.345 0.000
K10 Other diseases of jaws
0.654 0.346 0.000
F03 Unspecified dementia
0.653 0.347 0.000
N36.2 Urethral caruncle
0.653 0.347 0.000
T92 Sequelae of injuries of upper limb
0.652 0.348 0.000
I95.8 Other hypotension
0.651 0.348 0.000
I95.0 Idiopathic hypotension
0.651 0.348 0.000
R11 Nausea and vomiting
0.652 0.348 0.000
R55 Syncope and collapse
0.651 0.349 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.650 0.350 0.000
D50-D53 Nutritional anaemias
0.649 0.351 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.648 0.351 0.000
G96 Other disorders of central nervous system
0.647 0.353 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.647 0.353 0.000
K77 Liver disorders in diseases classified elsewhere
0.647 0.353 0.000
K71 Toxic liver disease
0.647 0.353 0.000
G62 Other polyneuropathies
0.647 0.353 0.000
K52 Other non-infective gastro-enteritis and colitis
0.646 0.354 0.000
K12.3 Oral mucositis (ulcerative)
0.644 0.355 0.000
G83 Other paralytic syndromes
0.644 0.356 0.000
O32.2 Maternal care for transverse and oblique lie
0.644 0.356 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.643 0.357 0.000
K70.3 Alcoholic cirrhosis of liver
0.643 0.357 0.000
N26 Unspecified contracted kidney
0.642 0.358 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.641 0.358 0.000
S62 Fracture at wrist and hand level
0.641 0.359 0.000
Y35-Y36 Legal intervention and operations of war
0.641 0.359 0.000
Y10-Y34 Event of undetermined intent
0.641 0.359 0.000
Y00-Y09 Assault
0.641 0.359 0.000
X85-X99 Assault
0.641 0.359 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.641 0.359 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.641 0.359 0.000
X30-X39 Exposure to forces of nature
0.641 0.359 0.000
X10-X19 Contact with heat and hot substances
0.641 0.359 0.000
X00-X09 Exposure to smoke, fire and flames
0.641 0.359 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.641 0.359 0.000
W75-W84 Other accidental threats to breathing
0.641 0.359 0.000
W65-W74 Accidental drowning and submersion
0.641 0.359 0.000
V98-V99 Other and unspecified transport accidents
0.641 0.359 0.000
V95-V97 Air and space transport accidents
0.641 0.359 0.000
V90-V94 Water transport accidents
0.641 0.359 0.000
V70-V79 Bus occupant injured in transport accident
0.641 0.359 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.641 0.359 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.641 0.359 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.641 0.359 0.000
V01-V09 Pedestrian injured in transport accident
0.641 0.359 0.000
M23 Internal derangement of knee
0.641 0.359 0.000
K74 Fibrosis and cirrhosis of liver
0.639 0.361 0.000
F32.1 Moderate depressive episode
0.638 0.362 0.000
J90-J94 Other diseases of pleura
0.638 0.362 0.000
M48.0 Spinal stenosis
0.638 0.362 0.000
E11.0 With coma
0.637 0.363 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.637 0.363 0.000
Q50-Q56 Congenital malformations of genital organs
0.637 0.363 0.000
Q35-Q37 Cleft lip and cleft palate
0.637 0.363 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.637 0.363 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.637 0.363 0.000
Q00-Q07 Congenital malformations of the nervous system
0.637 0.363 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.637 0.363 0.000
E87.2 Acidosis
0.637 0.363 0.000
N02 Recurrent and persistent haematuria
0.636 0.364 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.636 0.364 0.000
E11.3 With ophthalmic complications
0.636 0.364 0.000
R20.3 Hyperaesthesia
0.635 0.365 0.000
R20.1 Hypoaesthesia of skin
0.635 0.365 0.000
R20.0 Anaesthesia of skin
0.635 0.365 0.000
N42 Other disorders of prostate
0.635 0.365 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.634 0.366 0.000
Y57.9 Drug or medicament, unspecified
0.634 0.366 0.000
N48.0 Leukoplakia of penis
0.634 0.366 0.000
I20 Angina pectoris
0.634 0.366 0.000
N60-N64 Disorders of breast
0.634 0.366 0.000
E27.2 Addisonian crisis
0.634 0.366 0.000
S82.4 Fracture of fibula alone
0.634 0.366 0.000
R44.1 Visual hallucinations
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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