TreeWAS – Variant ID: rs7246967

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70-K77 Diseases of liver	0.388	0.612	0.000
K75 Other inflammatory liver diseases	0.384	0.616	0.000
K70 Alcoholic liver disease	0.378	0.622	0.000
K75.4 Autoimmune hepatitis	0.375	0.625	0.000
K70.9 Alcoholic liver disease, unspecified	0.370	0.630	0.000
K75.8 Other specified inflammatory liver diseases	0.369	0.631	0.000
K72 Hepatic failure, not elsewhere classified	0.352	0.648	0.000
K74 Fibrosis and cirrhosis of liver	0.343	0.657	0.000
K73 Chronic hepatitis, not elsewhere classified	0.336	0.664	0.000
K72.9 Hepatic failure, unspecified	0.324	0.676	0.000
K76 Other diseases of liver	0.316	0.684	0.000
K70.3 Alcoholic cirrhosis of liver	0.301	0.699	0.000
K70.4 Alcoholic hepatic failure	0.297	0.703	0.000
K74.0 Hepatic fibrosis	0.295	0.705	0.000
K74.6 Other and unspecified cirrhosis of liver	0.293	0.707	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.285	0.715	0.000
K76.9 Liver disease, unspecified	0.282	0.718	0.000
K77 Liver disorders in diseases classified elsewhere	0.278	0.722	0.000
K71 Toxic liver disease	0.278	0.722	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.275	0.724	0.000
K75.2 Nonspecific reactive hepatitis	0.275	0.724	0.000
K75.1 Phlebitis of portal vein	0.275	0.724	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.272	0.728	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.270	0.730	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.262	0.738	0.000
K72.0 Acute and subacute hepatic failure	0.260	0.740	0.000
K72.1 Chronic hepatic failure	0.252	0.748	0.000
K73.9 Chronic hepatitis, unspecified	0.248	0.752	0.000
K70.0 Alcoholic fatty liver	0.248	0.752	0.000
K70.1 Alcoholic hepatitis	0.247	0.753	0.000
K74.4 Secondary biliary cirrhosis	0.246	0.754	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.246	0.754	0.000
K74.1 Hepatic sclerosis	0.246	0.754	0.000
K74.3 Primary biliary cirrhosis	0.245	0.755	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.241	0.759	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.241	0.759	0.000
K76.5 Hepatic veno-occlusive disease	0.227	0.773	0.000
K76.4 Peliosis hepatis	0.227	0.773	0.000
K76.3 Infarction of liver	0.227	0.773	0.000
K76.2 Central haemorrhagic necrosis of liver	0.227	0.773	0.000
K76.1 Chronic passive congestion of liver	0.227	0.773	0.000
K75.9 Inflammatory liver disease, unspecified	0.224	0.776	0.000
K74.5 Biliary cirrhosis, unspecified	0.223	0.777	0.000
K76.7 Hepatorenal syndrome	0.208	0.792	0.000
K71.9 Toxic liver disease, unspecified	0.199	0.800	0.000
K71.8 Toxic liver disease with other disorders of liver	0.199	0.800	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.199	0.800	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.199	0.800	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.199	0.800	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.199	0.800	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.199	0.800	0.000
K71.2 Toxic liver disease with acute hepatitis	0.199	0.800	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.199	0.800	0.000
K71.0 Toxic liver disease with cholestasis	0.199	0.800	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.199	0.800	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.199	0.800	0.000
K76.8 Other specified diseases of liver	0.200	0.800	0.000
K75.0 Abscess of liver	0.181	0.819	0.000
K76.6 Portal hypertension	0.154	0.846	0.000
E14 Unspecified diabetes mellitus	0.121	0.879	0.000
E14.3 With ophthalmic complications	0.121	0.879	0.000
E10-E14 Diabetes mellitus	0.112	0.888	0.000
E10 Insulin-dependent diabetes mellitus	0.108	0.892	0.000
E14.9 Without complications	0.106	0.894	0.000
E10.3 With ophthalmic complications	0.100	0.900	0.000
E14.2 Withrenal complications	0.100	0.900	0.000
E11 Non-insulin-dependent diabetes mellitus	0.096	0.904	0.000
E10.2 With renal complications	0.095	0.905	0.000
E14.5 With peripheral circulatory complications	0.095	0.905	0.000
E14.1 With ketoacidosis	0.095	0.905	0.000
E11.5 With peripheral circulatory complications	0.094	0.906	0.000
E10.1 With ketoacidosis	0.093	0.907	0.000
E11.2 With renal complications	0.089	0.911	0.000
E14.8 With unspecified complications	0.087	0.913	0.000
E14.7 With multiple complications	0.087	0.913	0.000
E14.4 With neurological complications	0.087	0.913	0.000
E14.0 With coma	0.087	0.913	0.000
E14.6 With other specified complications	0.087	0.913	0.000
E13 Other specified diabetes mellitus	0.084	0.916	0.000
E10.8 With unspecified complications	0.084	0.916	0.000
E10.5 With peripheral circulatory complications	0.084	0.916	0.000
E11.1 With ketoacidosis	0.081	0.919	0.000
E12 Malnutrition-related diabetes mellitus	0.081	0.919	0.000
E11.4 With neurological complications	0.079	0.921	0.000
E10.7 With multiple complications	0.077	0.923	0.000
E10.6 With other specified complications	0.077	0.923	0.000
I77 Other disorders of arteries and arterioles	0.076	0.924	0.000
I77.1 Stricture of artery	0.076	0.924	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.076	0.924	0.000
E10.4 With neurological complications	0.075	0.925	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.074	0.926	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.072	0.928	0.000
E10.0 With coma	0.072	0.928	0.000
I70 Atherosclerosis	0.071	0.929	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.070	0.930	0.000
I71 Aortic aneurysm and dissection	0.070	0.930	0.000
E11.8 With unspecified complications	0.070	0.930	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.069	0.931	0.000
E11.7 With multiple complications	0.069	0.931	0.000
E13.3 With ophthalmic complications	0.068	0.932	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.061	0.939	0.000
E13.8 With unspecified complications	0.061	0.939	0.000
E13.7 With multiple complications	0.061	0.939	0.000
E13.6 With other specified complications	0.061	0.939	0.000
E13.5 With peripheral circulatory complications	0.061	0.939	0.000
E13.4 With neurological complications	0.061	0.939	0.000
E13.2 With renal complications	0.061	0.939	0.000
E13.1 With ketoacidosis	0.061	0.939	0.000
E13.0 With coma	0.061	0.939	0.000
E12.9 Without complications	0.058	0.942	0.000
E12.8 With unspecified complications	0.058	0.942	0.000
E12.7 With multiple complications	0.058	0.942	0.000
E12.6 With other specified complications	0.058	0.942	0.000
E12.5 With peripheral circulatory complications	0.058	0.942	0.000
E12.4 With neurological complications	0.058	0.942	0.000
E12.3 With ophthalmic complications	0.058	0.942	0.000
E12.2 With renal complications	0.058	0.942	0.000
E12.1 With ketoacidosis	0.058	0.942	0.000
E12.0 With coma	0.058	0.942	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.058	0.942	0.000
I74 Arterial embolism and thrombosis	0.057	0.943	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.057	0.943	0.000
E13.9 Without complications	0.055	0.945	0.000
I77.5 Necrosis of artery	0.055	0.945	0.000
I77.4 Coeliac artery compression syndrome	0.055	0.945	0.000
I77.3 Arterial fibromuscular dysplasia	0.055	0.945	0.000
I77.2 Rupture of artery	0.055	0.945	0.000
I70.9 Generalised and unspecified atherosclerosis	0.054	0.946	0.000
I77.8 Other specified disorders of arteries and arterioles	0.054	0.946	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.053	0.947	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.052	0.948	0.000
E11.6 With other specified complications	0.052	0.948	0.000
I78 Diseases of capillaries	0.052	0.948	0.000
I73 Other peripheral vascular diseases	0.051	0.949	0.000
I70.8 Atherosclerosis of other arteries	0.051	0.949	0.000
I71.0 Dissection of aorta [any part]	0.051	0.949	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.050	0.949	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.050	0.949	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.050	0.949	0.000
I70.1 Atherosclerosis of renal artery	0.049	0.951	0.000
I12.0 Hypertensive renal disease with renal failure	0.049	0.951	0.000
I73.9 Peripheral vascular disease, unspecified	0.047	0.953	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.045	0.954	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.045	0.955	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.044	0.956	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.044	0.956	0.000
I79.1 Aortitis in diseases classified elsewhere	0.044	0.956	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.044	0.956	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.042	0.957	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.042	0.958	0.000
I74.5 Embolism and thrombosis of iliac artery	0.041	0.958	0.000
F05.9 Delirium, unspecified	0.041	0.959	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.041	0.959	0.000
I72 Other aneurysm	0.040	0.959	0.000
I77.0 Arteriovenous fistula, acquired	0.040	0.959	0.000
I70.0 Atherosclerosis of aorta	0.040	0.960	0.000
I78.8 Other diseases of capillaries	0.040	0.960	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.039	0.961	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.039	0.961	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.037	0.963	0.000
I78.9 Disease of capillaries, unspecified	0.037	0.963	0.000
I73.8 Other specified peripheral vascular diseases	0.037	0.963	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.037	0.963	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.037	0.963	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.037	0.963	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.035	0.964	0.000
I74.8 Embolism and thrombosis of other arteries	0.034	0.966	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.034	0.966	0.000
E11.0 With coma	0.033	0.967	0.001
I78.1 Naevus, nonneoplastic	0.032	0.968	0.000
E11.3 With ophthalmic complications	0.032	0.968	0.000
I77.6 Arteritis, unspecified	0.030	0.970	0.000
C34.1 Upper lobe, bronchus or lung	0.030	0.970	0.000
I72.9 Aneurysm of unspecified site	0.029	0.970	0.000
I12 Hypertensive renal disease	0.029	0.971	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.029	0.971	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.029	0.971	0.000
I72.2 Aneurysm of renal artery	0.029	0.971	0.000
I72.1 Aneurysm of artery of upper extremity	0.029	0.971	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.029	0.971	0.000
I72.8 Aneurysm of other specified arteries	0.029	0.971	0.000
N03.9 Unspecified	0.029	0.971	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.029	0.971	0.000
C34 Malignant neoplasm of bronchus and lung	0.028	0.972	0.000
I72.0 Aneurysm of carotid artery	0.028	0.972	0.000
C34.9 Bronchus or lung, unspecified	0.027	0.973	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.027	0.973	0.000
I72.3 Aneurysm of iliac artery	0.026	0.974	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.025	0.975	0.000
C34.2 Middle lobe, bronchus or lung	0.025	0.975	0.000
C34.0 Main bronchus	0.025	0.975	0.000
N03 Chronic nephritic syndrome	0.024	0.976	0.000
E50-E64 Other nutritional deficiencies	0.024	0.976	0.000
I72.4 Aneurysm of artery of lower extremity	0.024	0.976	0.000
E16 Other disorders of pancreatic internal secretion	0.023	0.977	0.000
E86 Volume depletion	0.022	0.978	0.000
E70-E90 Metabolic disorders	0.022	0.978	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.022	0.978	0.000
N05.9 Unspecified	0.022	0.978	0.000
E55 Vitamin D deficiency	0.021	0.979	0.000
F05.1 Delirium superimposed on dementia	0.021	0.979	0.000
N00-N08 Glomerular diseases	0.021	0.979	0.000
E16.2 Hypoglycaemia, unspecified	0.021	0.979	0.000
I12.9 Hypertensive renal disease without renal failure	0.021	0.979	0.000
N05 Unspecified nephritic syndrome	0.021	0.979	0.000
C34.8 Overlapping lesion of bronchus and lung	0.020	0.979	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.020	0.980	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.020	0.980	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.020	0.980	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.020	0.980	0.000
E00-E07 Disorders of thyroid gland	0.020	0.980	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.020	0.980	0.000
E55.9 Vitamin D deficiency, unspecified	0.019	0.981	0.000
C67 Malignant neoplasm of bladder	0.000	0.981	0.019
C67.4 Posterior wall of bladder	0.000	0.981	0.019
E87.0 Hyperosmolality and hypernatraemia	0.019	0.981	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.019	0.981	0.000
E10.9 Without complications	0.019	0.981	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.018	0.982	0.001
E56 Other vitamin deficiencies	0.018	0.982	0.000
E15 Nondiabetic hypoglycaemic coma	0.018	0.982	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.018	0.982	0.000
F05.0 Delirium not superimposed on dementia, so described	0.018	0.982	0.000
N03.8 Other	0.018	0.982	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.018	0.982	0.000
N03.6 Dense deposit disease	0.018	0.982	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.018	0.982	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.018	0.982	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.018	0.982	0.000
N03.2 Diffuse membranous glomerulonephritis	0.018	0.982	0.000
N03.1 Focal and segmental glomerular lesions	0.018	0.982	0.000
N03.0 Minor glomerular abnormality	0.018	0.982	0.000
E40-E46 Malnutrition	0.017	0.982	0.000
C67.3 Anterior wall of bladder	0.000	0.982	0.017
E64 Sequelae of malnutrition and other nutritional deficiencies	0.017	0.983	0.000
E63 Other nutritional deficiencies	0.017	0.983	0.000
E51 Thiamine deficiency	0.017	0.983	0.000
E50 Vitamin A deficiency	0.017	0.983	0.000
E60 Dietary zinc deficiency	0.017	0.983	0.000
E59 Dietary selenium deficiency	0.017	0.983	0.000
E58 Dietary calcium deficiency	0.017	0.983	0.000
E54 Ascorbic acid deficiency	0.017	0.983	0.000
E52 Niacin deficiency [pellagra]	0.017	0.983	0.000
F05.8 Other delirium	0.017	0.983	0.000
E16.1 Other hypoglycaemia	0.017	0.983	0.000
E74 Other disorders of carbohydrate metabolism	0.017	0.983	0.000
E79 Disorders of purine and pyrimidine metabolism	0.017	0.983	0.000
F02 Dementia in other diseases classified elsewhere	0.017	0.983	0.000
C67.2 Lateral wall of bladder	0.000	0.983	0.017
E16.9 Disorder of pancreatic internal secretion, unspecified	0.016	0.983	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.016	0.983	0.000
E16.4 Abnormal secretion of gastrin	0.016	0.983	0.000
E16.3 Increased secretion of glucagon	0.016	0.983	0.000
E53 Deficiency of other B group vitamins	0.016	0.984	0.000
C67.0 Trigone of bladder	0.000	0.984	0.016
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.016	0.984	0.000
E84 Cystic fibrosis	0.016	0.984	0.000
E77 Disorders of glycoprotein metabolism	0.016	0.984	0.000
E76 Disorders of glycosaminoglycan metabolism	0.016	0.984	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.016	0.984	0.000
E72 Other disorders of amino-acid metabolism	0.016	0.984	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.016	0.984	0.000
E70 Disorders of aromatic amino-acid metabolism	0.016	0.984	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.016	0.984	0.000
C67.8 Overlapping lesion of bladder	0.000	0.984	0.016
E16.0 Drug-induced hypoglycaemia without coma	0.016	0.984	0.000
N05.2 Diffuse membranous glomerulonephritis	0.016	0.984	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.016	0.984	0.000
E73 Lactose intolerance	0.016	0.984	0.000
E61 Deficiency of other nutrient elements	0.016	0.984	0.000
I10-I15 Hypertensive diseases	0.016	0.984	0.000
N41.1 Chronic prostatitis	0.016	0.984	0.000
C67.5 Bladder neck	0.000	0.984	0.016
E80 Disorders of porphyrin and bilirubin metabolism	0.015	0.984	0.000
E55.0 Rickets, active	0.015	0.984	0.000
C67.1 Dome of bladder	0.000	0.985	0.015
N07 Hereditary nephropathy, not elsewhere classified	0.015	0.985	0.000
N06 Isolated proteinuria with specified morphological lesion	0.015	0.985	0.000
N01 Rapidly progressive nephritic syndrome	0.015	0.985	0.000
N00 Acute nephritic syndrome	0.015	0.985	0.000
F02.3 Dementia in Parkinson's disease	0.015	0.985	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.015	0.985	0.000
N05.6 Dense deposit disease	0.015	0.985	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.015	0.985	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.015	0.985	0.000
N05.0 Minor glomerular abnormality	0.015	0.985	0.000
E85 Amyloidosis	0.015	0.985	0.000
F01 Vascular dementia	0.015	0.985	0.000
F00 Dementia in Alzheimer's disease	0.015	0.985	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.014	0.985	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.014	0.985	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.014	0.985	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.014	0.985	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.014	0.985	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.014	0.985	0.000
C34.3 Lower lobe, bronchus or lung	0.014	0.985	0.000
E56.1 Deficiency of vitamin K	0.014	0.986	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E00 Congenital iodine-deficiency syndrome	0.014	0.986	0.000
E87.7 Fluid overload	0.014	0.986	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.014	0.986	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.014	0.986	0.000
R33 Retention of urine	0.000	0.986	0.014
E05.5 Thyroid crisis or storm	0.014	0.986	0.000
E05.4 Thyrotoxicosis factitia	0.014	0.986	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.014	0.986	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.014	0.986	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.986	0.014
E87.3 Alkalosis	0.014	0.986	0.000
C67.7 Urachus	0.000	0.986	0.014
E05.8 Other thyrotoxicosis	0.014	0.986	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.014	0.986	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.014	0.986	0.000
E78.1 Pure hyperglyceridaemia	0.014	0.986	0.000
F09 Unspecified organic or symptomatic mental disorder	0.013	0.986	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.013	0.986	0.000
N04 Nephrotic syndrome	0.013	0.986	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.986	0.013
E56.9 Vitamin deficiency, unspecified	0.013	0.987	0.000
E56.8 Deficiency of other vitamins	0.013	0.987	0.000
E56.0 Deficiency of vitamin E	0.013	0.987	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.013	0.987	0.000
E87.4 Mixed disorder of acid-base balance	0.013	0.987	0.000
N05.8 Other	0.013	0.987	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.013	0.987	0.000
E03 Other hypothyroidism	0.013	0.987	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.013	0.987	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.013	0.987	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.013	0.987	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.013	0.987	0.000
E45 Retarded development following protein-energy malnutrition	0.013	0.987	0.000
E43 Unspecified severe protein-energy malnutrition	0.013	0.987	0.000
E42 Marasmic kwashiorkor	0.013	0.987	0.000
E41 Nutritional marasmus	0.013	0.987	0.000
E40 Kwashiorkor	0.013	0.987	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.987	0.013
E50.9 Vitamin A deficiency, unspecified	0.013	0.987	0.000
E50.8 Other manifestations of vitamin A deficiency	0.013	0.987	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.013	0.987	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.013	0.987	0.000
E50.5 Vitamin A deficiency with night blindness	0.013	0.987	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.013	0.987	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.013	0.987	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.013	0.987	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.013	0.987	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.013	0.987	0.000
E51.9 Thiamine deficiency, unspecified	0.013	0.987	0.000
E51.8 Other manifestations of thiamine deficiency	0.013	0.987	0.000
E51.2 Wernicke's encephalopathy	0.013	0.987	0.000
E51.1 Beriberi	0.013	0.987	0.000
E63.9 Nutritional deficiency, unspecified	0.013	0.987	0.000
E63.8 Other specified nutritional deficiencies	0.013	0.987	0.000
E63.1 Imbalance of constituents of food intake	0.013	0.987	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.013	0.987	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.013	0.987	0.000
E64.8 Sequelae of other nutritional deficiencies	0.013	0.987	0.000
E64.3 Sequelae of rickets	0.013	0.987	0.000
E64.2 Sequelae of vitamin C deficiency	0.013	0.987	0.000
E64.1 Sequelae of vitamin A deficiency	0.013	0.987	0.000
E64.0 Sequelae of protein-energy malnutrition	0.013	0.987	0.000
E78.4 Other hyperlipidaemia	0.013	0.987	0.000
Chapter IX Diseases of the circulatory system	0.013	0.987	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.012	0.987	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.012	0.987	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.012	0.987	0.000
E74.2 Disorders of galactose metabolism	0.012	0.987	0.000
E74.1 Disorders of fructose metabolism	0.012	0.987	0.000
E74.0 Glycogen storage disease	0.012	0.987	0.000
I15 Secondary hypertension	0.013	0.987	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.012	0.988	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.012	0.988	0.000
E79.1 Lesch-Nyhan syndrome	0.012	0.988	0.000
E65-E68 Obesity and other hyperalimentation	0.011	0.988	0.002
C67.6 Ureteric orifice	0.000	0.988	0.012
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.012	0.988	0.000
F02.2 Dementia in Huntington's disease	0.012	0.988	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.012	0.988	0.000
E88 Other metabolic disorders	0.012	0.988	0.000
E03.8 Other specified hypothyroidism	0.012	0.988	0.000
F02.0 Dementia in Pick's disease	0.012	0.988	0.000
K35 Acute appendicitis	0.000	0.988	0.012
E89.2 Postprocedural hypoparathyroidism	0.012	0.988	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.012	0.988	0.000
F01.9 Vascular dementia, unspecified	0.012	0.988	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.988	0.012
E53.9 Vitamin B deficiency, unspecified	0.012	0.988	0.000
E53.1 Pyridoxine deficiency	0.012	0.988	0.000
E53.0 Riboflavin deficiency	0.012	0.988	0.000
K22.2 Oesophageal obstruction	0.012	0.988	0.000
I05 Rheumatic mitral valve diseases	0.012	0.988	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.012	0.988	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.012	0.988	0.000
E70.3 Albinism	0.012	0.988	0.000
E70.2 Disorders of tyrosine metabolism	0.012	0.988	0.000
E70.1 Other hyperphenylalaninaemias	0.012	0.988	0.000
E70.0 Classical phenylketonuria	0.012	0.988	0.000
E71.3 Disorders of fatty-acid metabolism	0.012	0.988	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.012	0.988	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.012	0.988	0.000
E71.0 Maple-syrup-urine disease	0.012	0.988	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.012	0.988	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.012	0.988	0.000
E72.5 Disorders of glycine metabolism	0.012	0.988	0.000
E72.4 Disorders of ornithine metabolism	0.012	0.988	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.012	0.988	0.000
E72.2 Disorders of urea cycle metabolism	0.012	0.988	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.012	0.988	0.000
E72.0 Disorders of amino-acid transport	0.012	0.988	0.000
E75.6 Lipid storage disorder, unspecified	0.012	0.988	0.000
E75.5 Other lipid storage disorders	0.012	0.988	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.012	0.988	0.000
E75.3 Sphingolipidosis, unspecified	0.012	0.988	0.000
E75.2 Other sphingolipidosis	0.012	0.988	0.000
E75.1 Other gangliosidosis	0.012	0.988	0.000
E75.0 GM2 gangliosidosis	0.012	0.988	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.012	0.988	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.012	0.988	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.012	0.988	0.000
E76.2 Other mucopolysaccharidoses	0.012	0.988	0.000
E76.1 Mucopolysaccharidosis, type II	0.012	0.988	0.000
E76.0 Mucopolysaccharidosis, type I	0.012	0.988	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.012	0.988	0.000
E77.8 Other disorders of glycoprotein metabolism	0.012	0.988	0.000
E77.1 Defects in glycoprotein degradation	0.012	0.988	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.012	0.988	0.000
E84.9 Cystic fibrosis, unspecified	0.012	0.988	0.000
E84.8 Cystic fibrosis with other manifestations	0.012	0.988	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.012	0.988	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.012	0.988	0.000
E05.9 Thyrotoxicosis, unspecified	0.012	0.988	0.000
E73.8 Other lactose intolerance	0.012	0.988	0.000
E73.1 Secondary lactase deficiency	0.012	0.988	0.000
E73.0 Congenital lactase deficiency	0.012	0.988	0.000
E61.9 Deficiency of nutrient element, unspecified	0.012	0.988	0.000
E61.8 Deficiency of other specified nutrient elements	0.012	0.988	0.000
E61.7 Deficiency of multiple nutrient elements	0.012	0.988	0.000
E61.6 Vanadium deficiency	0.012	0.988	0.000
E61.5 Molybdenum deficiency	0.012	0.988	0.000
E61.4 Chromium deficiency	0.012	0.988	0.000
E61.3 Manganese deficiency	0.012	0.988	0.000
E61.0 Copper deficiency	0.012	0.988	0.000
I13 Hypertensive heart and renal disease	0.012	0.988	0.000
N05.1 Focal and segmental glomerular lesions	0.011	0.988	0.000
I05-I09 Chronic rheumatic heart diseases	0.012	0.988	0.000
E73.9 Lactose intolerance, unspecified	0.011	0.988	0.000
I05.0 Mitral stenosis	0.011	0.989	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.989	0.011
E80.7 Disorder of bilirubin metabolism, unspecified	0.011	0.989	0.000
E80.6 Other disorders of bilirubin metabolism	0.011	0.989	0.000
E80.5 Crigler-Najjar syndrome	0.011	0.989	0.000
E80.3 Defects of catalase and peroxydase	0.011	0.989	0.000
E80.2 Other porphyria	0.011	0.989	0.000
E80.1 Porphyria cutanea tarda	0.011	0.989	0.000
E80.0 Hereditary erythropoietic porphyria	0.011	0.989	0.000
F07.2 Postconcussional syndrome	0.011	0.989	0.000
E07 Other disorders of thyroid	0.011	0.989	0.000
E85.4 Organ-limited amyloidosis	0.011	0.989	0.000
N00.9 Unspecified	0.011	0.989	0.000
N00.8 Other	0.011	0.989	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N00.6 Dense deposit disease	0.011	0.989	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.011	0.989	0.000
N00.2 Diffuse membranous glomerulonephritis	0.011	0.989	0.000
N00.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N00.0 Minor glomerular abnormality	0.011	0.989	0.000
N01.9 Unspecified	0.011	0.989	0.000
N01.8 Other	0.011	0.989	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N01.6 Dense deposit disease	0.011	0.989	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.011	0.989	0.000
N01.2 Diffuse membranous glomerulonephritis	0.011	0.989	0.000
N01.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N01.0 Minor glomerular abnormality	0.011	0.989	0.000
N06.9 Unspecified	0.011	0.989	0.000
N06.8 Other	0.011	0.989	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N06.6 Dense deposit disease	0.011	0.989	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.011	0.989	0.000
N06.2 Diffuse membranous glomerulonephritis	0.011	0.989	0.000
N06.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N06.0 Minor glomerular abnormality	0.011	0.989	0.000
N07.9 Unspecified	0.011	0.989	0.000
N07.8 Other	0.011	0.989	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N07.6 Dense deposit disease	0.011	0.989	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.011	0.989	0.000
N07.2 Diffuse membranous glomerulonephritis	0.011	0.989	0.000
N07.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N07.0 Minor glomerular abnormality	0.011	0.989	0.000
I11 Hypertensive heart disease	0.011	0.989	0.000
E61.2 Magnesium deficiency	0.011	0.989	0.000
E85.8 Other amyloidosis	0.011	0.989	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations