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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72649226
log Bayes Factor = 15.4053
Chromosome 8   position 64,550,665  (GRCh37) Explore rs72649226 on Ensembl!
Variant rs72649226 is part of Cluster X0071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.999 0.001 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
J20-J22 Other acute lower respiratory infections
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
J22 Unspecified acute lower respiratory infection
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
C15-C26 Malignant neoplasms of digestive organs
0.986 0.014 0.000
R05 Cough
0.984 0.016 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.984 0.016 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.983 0.017 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.983 0.017 0.000
E20-E35 Disorders of other endocrine glands
0.974 0.026 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.974 0.026 0.000
R07 Pain in throat and chest
0.966 0.034 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.963 0.037 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.963 0.037 0.000
I30-I52 Other forms of heart disease
0.960 0.040 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.953 0.047 0.000
R07.4 Chest pain, unspecified
0.950 0.050 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.949 0.051 0.000
Chapter XXII Codes for special purposes
0.944 0.056 0.000
C25 Malignant neoplasm of pancreas
0.943 0.057 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.939 0.061 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.936 0.064 0.000
E65-E68 Obesity and other hyperalimentation
0.935 0.065 0.000
C15 Malignant neoplasm of oesophagus
0.929 0.071 0.000
C83.3 Large cell (diffuse)
0.929 0.071 0.000
I51 Complications and ill-defined descriptions of heart disease
0.925 0.075 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.924 0.076 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.921 0.079 0.000
J90-J94 Other diseases of pleura
0.918 0.082 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.916 0.084 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.913 0.087 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.910 0.090 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.910 0.090 0.000
I05-I09 Chronic rheumatic heart diseases
0.907 0.093 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.905 0.095 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.904 0.096 0.000
Chapter I Certain infectious and parasitic diseases
0.904 0.096 0.000
G95 Other diseases of spinal cord
0.900 0.100 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.898 0.102 0.000
C85.1 B-cell lymphoma, unspecified
0.896 0.104 0.000
O80-O84 Delivery
0.895 0.105 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.895 0.105 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.888 0.112 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.883 0.117 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.883 0.117 0.000
J95-J99 Other diseases of the respiratory system
0.880 0.120 0.000
R79 Other abnormal findings of blood chemistry
0.880 0.120 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.880 0.120 0.000
O26.8 Other specified pregnancy-related conditions
0.878 0.122 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.877 0.123 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.877 0.123 0.000
I35 Nonrheumatic aortic valve disorders
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.876 0.124 0.000
E66 Obesity
0.873 0.127 0.000
E21.0 Primary hyperparathyroidism
0.872 0.128 0.000
C17 Malignant neoplasm of small intestine
0.870 0.130 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.867 0.133 0.000
R07.2 Precordial pain
0.867 0.133 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.862 0.138 0.000
C25.9 Pancreas, unspecified
0.860 0.140 0.000
G93 Other disorders of brain
0.860 0.140 0.000
J90 Pleural effusion, not elsewhere classified
0.857 0.143 0.000
E28 Ovarian dysfunction
0.857 0.143 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.856 0.144 0.000
J60-J70 Lung diseases due to external agents
0.853 0.147 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.852 0.148 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.850 0.150 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
S80-S89 Injuries to the knee and lower leg
0.849 0.151 0.000
C60-C63 Malignant neoplasms of male genital organs
0.849 0.151 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.846 0.154 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.845 0.155 0.000
C25.0 Head of pancreas
0.844 0.156 0.000
J30-J39 Other diseases of upper respiratory tract
0.841 0.159 0.000
I34 Nonrheumatic mitral valve disorders
0.840 0.160 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.840 0.160 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.840 0.160 0.000
O85-O92 Complications predominantly related to the puerperium
0.838 0.162 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.836 0.164 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.835 0.165 0.000
I33 Acute and subacute endocarditis
0.834 0.166 0.000
I95 Hypotension
0.830 0.170 0.000
O80 Single spontaneous delivery
0.829 0.171 0.000
I51.8 Other ill-defined heart diseases
0.828 0.172 0.000
C91 Lymphoid leukaemia
0.827 0.173 0.000
Q80-Q89 Other congenital malformations
0.827 0.173 0.000
C15.9 Oesophagus, unspecified
0.821 0.179 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.820 0.180 0.000
M05-M14 Inflammatory polyarthropathies
0.820 0.180 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.820 0.180 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.817 0.183 0.000
O23 Infections of genito-urinary tract in pregnancy
0.816 0.184 0.000
Q60-Q64 Congenital malformations of the urinary system
0.812 0.188 0.000
I95.9 Hypotension, unspecified
0.812 0.188 0.000
M45-M49 Spondylopathies
0.808 0.192 0.000
O20 Haemorrhage in early pregnancy
0.808 0.192 0.000
I05 Rheumatic mitral valve diseases
0.807 0.193 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.805 0.195 0.000
V80-V89 Other land transport accidents
0.803 0.197 0.000
I51.9 Heart disease, unspecified
0.803 0.197 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.801 0.199 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.799 0.201 0.000
O21 Excessive vomiting in pregnancy
0.799 0.201 0.000
Chapter XXI Factors influencing health status and contact with health services
0.799 0.201 0.000
C16 Malignant neoplasm of stomach
0.798 0.202 0.000
Y95 Nosocomial condition
0.796 0.204 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.795 0.205 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.794 0.206 0.000
B95-B98 Bacterial, viral and other infectious agents
0.794 0.206 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.793 0.207 0.000
U80 Agent resistant to penicillin and related antibiotics
0.793 0.207 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.792 0.208 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
V40-V49 Car occupant injured in transport accident
0.787 0.213 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.787 0.213 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.785 0.215 0.000
E27 Other disorders of adrenal gland
0.784 0.216 0.000
G30-G32 Other degenerative diseases of the nervous system
0.783 0.217 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.783 0.217 0.000
E66.8 Other obesity
0.781 0.219 0.000
E70-E90 Metabolic disorders
0.781 0.219 0.000
D37.5 Rectum
0.780 0.220 0.000
Y52 Agents primarily affecting the cardiovascular system
0.779 0.221 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.778 0.222 0.000
G54 Nerve root and plexus disorders
0.778 0.222 0.000
S80 Superficial injury of lower leg
0.776 0.224 0.000
C15.3 Upper third of oesophagus
0.776 0.224 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.775 0.225 0.000
I34.1 Mitral (valve) prolapse
0.775 0.225 0.000
Q23 Congenital malformations of aortic and mitral valves
0.774 0.226 0.000
O80.0 Spontaneous vertex delivery
0.773 0.227 0.000
E65 Localised adiposity
0.773 0.227 0.000
E28.2 Polycystic ovarian syndrome
0.773 0.227 0.000
X50-X57 Overexertion, travel and privation
0.772 0.228 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.771 0.229 0.000
E29 Testicular dysfunction
0.771 0.229 0.000
Q27 Other congenital malformations of peripheral vascular system
0.770 0.230 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.770 0.230 0.000
B15-B19 Viral hepatitis
0.769 0.231 0.000
G95.2 Cord compression, unspecified
0.768 0.232 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.766 0.234 0.000
C83.0 Small cell (diffuse)
0.765 0.234 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
U51 Admission status on psychiatric patients
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.763 0.237 0.000
R09.1 Pleurisy
0.762 0.238 0.000
M81 Osteoporosis without pathological fracture
0.762 0.238 0.000
W00-W19 Falls
0.760 0.240 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.759 0.241 0.000
G51 Facial nerve disorders
0.759 0.241 0.000
I35.0 Aortic (valve) stenosis
0.759 0.241 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.758 0.242 0.000
D37.7 Other digestive organs
0.758 0.242 0.000
E40-E46 Malnutrition
0.758 0.242 0.000
R79.0 Abnormal level of blood mineral
0.758 0.242 0.000
M47 Spondylosis
0.758 0.242 0.000
J39 Other diseases of upper respiratory tract
0.756 0.243 0.000
E66.9 Obesity, unspecified
0.756 0.244 0.000
V10-V19 Pedal cyclist injured in transport accident
0.755 0.245 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.754 0.246 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
C20 Malignant neoplasm of rectum
0.754 0.246 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.753 0.247 0.000
I51.7 Cardiomegaly
0.752 0.248 0.000
C17.9 Small intestine, unspecified
0.751 0.249 0.000
G95.9 Disease of spinal cord, unspecified
0.751 0.249 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.750 0.249 0.000
M40-M43 Deforming dorsopathies
0.750 0.249 0.000
J33 Nasal polyp
0.749 0.251 0.000
Y00-Y09 Assault
0.748 0.252 0.000
R02 Gangrene, not elsewhere classified
0.746 0.254 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.746 0.254 0.000
E22 Hyperfunction of pituitary gland
0.746 0.254 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.746 0.254 0.000
R45 Symptoms and signs involving emotional state
0.744 0.256 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.744 0.256 0.000
I35.1 Aortic (valve) insufficiency
0.744 0.256 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.744 0.256 0.000
I33.0 Acute and subacute infective endocarditis
0.743 0.256 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.743 0.257 0.000
C88 Malignant immunoproliferative diseases
0.742 0.258 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.742 0.258 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.741 0.258 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.741 0.259 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.740 0.260 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.739 0.261 0.000
I37 Pulmonary valve disorders
0.737 0.263 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.735 0.265 0.000
C92 Myeloid leukaemia
0.735 0.265 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.734 0.266 0.000
R80 Isolated proteinuria
0.732 0.268 0.000
D80-D89 Certain disorders involving the immune mechanism
0.731 0.269 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.730 0.270 0.000
I30 Acute pericarditis
0.730 0.270 0.000
I07 Rheumatic tricuspid valve diseases
0.729 0.271 0.000
T92 Sequelae of injuries of upper limb
0.729 0.271 0.000
I42 Cardiomyopathy
0.729 0.271 0.000
C61 Malignant neoplasm of prostate
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.728 0.272 0.000
C15.4 Middle third of oesophagus
0.728 0.272 0.000
E23 Hypofunction and other disorders of pituitary gland
0.727 0.273 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.727 0.273 0.000
J98 Other respiratory disorders
0.727 0.273 0.000
Q24 Other congenital malformations of heart
0.727 0.273 0.000
D46 Myelodysplastic syndromes
0.726 0.273 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.726 0.274 0.000
R09.0 Asphyxia
0.726 0.274 0.000
J32 Chronic sinusitis
0.725 0.275 0.000
R07.1 Chest pain on breathing
0.725 0.275 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.725 0.275 0.000
I31 Other diseases of pericardium
0.724 0.276 0.000
I49 Other cardiac arrhythmias
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.722 0.278 0.000
C45 Mesothelioma
0.722 0.278 0.000
J69 Pneumonitis due to solids and liquids
0.721 0.279 0.000
T90 Sequelae of injuries of head
0.721 0.279 0.000
J91 Pleural effusion in conditions classified elsewhere
0.719 0.280 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.719 0.281 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.719 0.281 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.718 0.282 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y84.8 Other medical procedures
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.716 0.284 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
C95 Leukaemia of unspecified cell type
0.716 0.284 0.000
C94 Other leukaemias of specified cell type
0.716 0.284 0.000
C93 Monocytic leukaemia
0.716 0.284 0.000
C86 Other specified types of T/NK-cell lymphoma
0.716 0.284 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.716 0.284 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.715 0.285 0.000
I46 Cardiac arrest
0.714 0.286 0.000
S80.9 Superficial injury of lower leg, unspecified
0.714 0.286 0.000
J21 Acute bronchiolitis
0.713 0.287 0.000
T98 Sequelae of other and unspecified effects of external causes
0.713 0.287 0.000
I71 Aortic aneurysm and dissection
0.712 0.288 0.000
G95.1 Vascular myelopathies
0.712 0.288 0.000
G58 Other mononeuropathies
0.710 0.290 0.000
O24 Diabetes mellitus in pregnancy
0.710 0.290 0.000
F30-F39 Mood [affective] disorders
0.709 0.291 0.000
C15.5 Lower third of oesophagus
0.708 0.291 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.707 0.293 0.000
C23 Malignant neoplasm of gallbladder
0.707 0.293 0.000
F10.1 Harmful use
0.707 0.293 0.000
R94 Abnormal results of function studies
0.706 0.293 0.000
Q50-Q56 Congenital malformations of genital organs
0.706 0.294 0.000
T91 Sequelae of injuries of neck and trunk
0.706 0.294 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
E24 Cushing's syndrome
0.705 0.295 0.000
R06 Abnormalities of breathing
0.705 0.295 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.705 0.295 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.705 0.295 0.000
C85.0 Lymphosarcoma
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
M06 Other rheumatoid arthritis
0.705 0.295 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.705 0.295 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.295 0.000
Q35-Q37 Cleft lip and cleft palate
0.705 0.295 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.705 0.295 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.705 0.295 0.000
I08 Multiple valve diseases
0.704 0.296 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
I77 Other disorders of arteries and arterioles
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.298 0.000
E50-E64 Other nutritional deficiencies
0.701 0.299 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.700 0.299 0.000
I05.9 Mitral valve disease, unspecified
0.701 0.299 0.000
C21 Malignant neoplasm of anus and anal canal
0.700 0.300 0.000
C34 Malignant neoplasm of bronchus and lung
0.700 0.300 0.000
B35-B49 Mycoses
0.700 0.300 0.000
M85 Other disorders of bone density and structure
0.699 0.301 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.699 0.301 0.000
E34 Other endocrine disorders
0.699 0.301 0.000
E32 Diseases of thymus
0.699 0.301 0.000
E31 Polyglandular dysfunction
0.699 0.301 0.000
E30 Disorders of puberty, not elsewhere classified
0.699 0.301 0.000
E26 Hyperaldosteronism
0.699 0.301 0.000
E25 Adrenogenital disorders
0.699 0.301 0.000
E20 Hypoparathyroidism
0.699 0.301 0.000
O29 Complications of anaesthesia during pregnancy
0.698 0.302 0.000
O28 Abnormal findings on antenatal screening of mother
0.698 0.302 0.000
O22 Venous complications in pregnancy
0.698 0.302 0.000
O25 Malnutrition in pregnancy
0.698 0.302 0.000
T85.2 Mechanical complication of intraocular lens
0.698 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.697 0.303 0.000
C17.0 Duodenum
0.696 0.304 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.695 0.305 0.000
M05 Seropositive rheumatoid arthritis
0.695 0.305 0.000
G95.8 Other specified diseases of spinal cord
0.695 0.305 0.000
M82 Osteoporosis in diseases classified elsewhere
0.694 0.306 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.693 0.306 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.693 0.307 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.693 0.307 0.000
J39.2 Other diseases of pharynx
0.692 0.308 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.691 0.309 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.691 0.309 0.000
C83.7 Burkitt's tumour
0.691 0.309 0.000
C83.6 Undifferentiated (diffuse)
0.691 0.309 0.000
C83.5 Lymphoblastic (diffuse)
0.691 0.309 0.000
C83.4 Immunoblastic (diffuse)
0.691 0.309 0.000
C83.2 Mixed small and large cell (diffuse)
0.691 0.309 0.000
C83.1 Small cleaved cell (diffuse)
0.691 0.309 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.690 0.310 0.000
G90 Disorders of autonomic nervous system
0.690 0.310 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.690 0.310 0.000
G92 Toxic encephalopathy
0.690 0.310 0.000
Y86 Sequelae of other accidents
0.689 0.311 0.000
I52 Other heart disorders in diseases classified elsewhere
0.688 0.311 0.000
I48 Atrial fibrillation and flutter
0.688 0.311 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.688 0.311 0.000
I41 Myocarditis in diseases classified elsewhere
0.688 0.311 0.000
I40 Acute myocarditis
0.688 0.311 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.688 0.311 0.000
I32 Pericarditis in diseases classified elsewhere
0.688 0.311 0.000
Q00-Q07 Congenital malformations of the nervous system
0.688 0.312 0.000
O90 Complications of the puerperium, not elsewhere classified
0.688 0.312 0.000
D37.9 Digestive organ, unspecified
0.687 0.313 0.000
Z50 Care involving use of rehabilitation procedures
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.685 0.314 0.000
M81.9 Osteoporosis, unspecified
0.685 0.315 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.683 0.317 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.683 0.317 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.683 0.317 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.683 0.317 0.000
G91 Hydrocephalus
0.681 0.319 0.000
R45.1 Restlessness and agitation
0.681 0.319 0.000
Z43 Attention to artificial openings
0.680 0.320 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.680 0.320 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.680 0.320 0.000
A00-A09 Intestinal infectious diseases
0.680 0.320 0.000
S70-S79 Injuries to the hip and thigh
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.321 0.000
Chapter VIII Diseases of the ear and mastoid process
0.679 0.321 0.000
G70-G73 Diseases of myoneural junction and muscle
0.679 0.321 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.679 0.321 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.678 0.321 0.000
S82 Fracture of lower leg, including ankle
0.678 0.322 0.000
R81 Glycosuria
0.678 0.322 0.000
G93.9 Disorder of brain, unspecified
0.678 0.322 0.000
C91.0 Acute lymphoblastic leukaemia
0.677 0.323 0.000
Q23.1 Congenital insufficiency of aortic valve
0.677 0.323 0.000
C25.8 Overlapping lesion of pancreas
0.676 0.324 0.000
C25.7 Other parts of pancreas
0.676 0.324 0.000
C25.4 Endocrine pancreas
0.676 0.324 0.000
C25.3 Pancreatic duct
0.676 0.324 0.000
C25.2 Tail of pancreas
0.676 0.324 0.000
C25.1 Body of pancreas
0.676 0.324 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.675 0.324 0.000
S81 Open wound of lower leg
0.676 0.324 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.675 0.325 0.000
M47.8 Other spondylosis
0.675 0.325 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.675 0.325 0.000
Z51 Other medical care
0.674 0.326 0.000
O21.9 Vomiting of pregnancy, unspecified
0.673 0.327 0.000
Y83.3 Surgical operation with formation of external stoma
0.673 0.327 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.673 0.327 0.000
G52 Disorders of other cranial nerves
0.673 0.327 0.000
O80.8 Other single spontaneous delivery
0.672 0.328 0.000
J94 Other pleural conditions
0.672 0.328 0.000
G93.4 Encephalopathy, unspecified
0.672 0.328 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
F17.1 Harmful use
0.671 0.329 0.000
J20 Acute bronchitis
0.670 0.330 0.000
E67 Other hyperalimentation
0.670 0.330 0.000
E68 Sequelae of hyperalimentation
0.670 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.670 0.330 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.670 0.330 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.670 0.330 0.000
Q27.3 Peripheral arteriovenous malformation
0.669 0.331 0.000
Y44 Agents primarily affecting blood constituents
0.669 0.331 0.000
E87.2 Acidosis
0.669 0.331 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.668 0.332 0.000
I36 Nonrheumatic tricuspid valve disorders
0.668 0.332 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.332 0.000
D43.2 Brain, unspecified
0.667 0.332 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.667 0.333 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.667 0.333 0.000
E27.9 Disorder of adrenal gland, unspecified
0.667 0.333 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.667 0.333 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.667 0.333 0.000
Y40 Systemic antibiotics
0.667 0.333 0.000
J86 Pyothorax
0.666 0.334 0.000
C15.8 Overlapping lesion of oesophagus
0.666 0.334 0.000
C15.2 Abdominal part of oesophagus
0.666 0.334 0.000
C15.1 Thoracic part of oesophagus
0.666 0.334 0.000
C15.0 Cervical part of oesophagus
0.666 0.334 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.666 0.334 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.665 0.334 0.000
R47-R49 Symptoms and signs involving speech and voice
0.665 0.335 0.000
W18 Other fall on same level
0.665 0.335 0.000
G93.3 Postviral fatigue syndrome
0.665 0.335 0.000
I82 Other venous embolism and thrombosis
0.664 0.336 0.000
Y43 Primarily systemic agents
0.664 0.336 0.000
O87 Venous complications in the puerperium
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.663 0.336 0.000
I51.5 Myocardial degeneration
0.663 0.337 0.000
I51.4 Myocarditis, unspecified
0.663 0.337 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.663 0.337 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.663 0.337 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.663 0.337 0.000
I51.0 Cardiac septal defect, acquired
0.663 0.337 0.000
O16 Unspecified maternal hypertension
0.663 0.337 0.000
M50-M54 Other dorsopathies
0.663 0.337 0.000
T33-T35 Frostbite
0.663 0.337 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.663 0.337 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.663 0.337 0.000
T00-T07 Injuries involving multiple body regions
0.663 0.337 0.000
R74 Abnormal serum enzyme levels
0.663 0.337 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
M60-M63 Disorders of muscles
0.662 0.338 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.662 0.338 0.000
S50-S59 Injuries to the elbow and forearm
0.661 0.339 0.000
M43 Other deforming dorsopathies
0.661 0.339 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.661 0.339 0.000
O15 Eclampsia
0.660 0.340 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.660 0.340 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.660 0.340 0.000
I49.0 Ventricular fibrillation and flutter
0.660 0.340 0.000
R03.1 Nonspecific low blood-pressure reading
0.660 0.340 0.000
J98.1 Pulmonary collapse
0.659 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.657 0.343 0.000
E21.4 Other specified disorders of parathyroid gland
0.657 0.343 0.000
E21.2 Other hyperparathyroidism
0.657 0.343 0.000
S20-S29 Injuries to the thorax
0.657 0.343 0.000
D86 Sarcoidosis
0.656 0.344 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.656 0.344 0.000
Y84.1 Kidney dialysis
0.656 0.344 0.000
R46 Symptoms and signs involving appearance and behaviour
0.655 0.345 0.000
Q21 Congenital malformations of cardiac septa
0.655 0.345 0.000
M00-M03 Infectious arthropathies
0.655 0.345 0.000
Z51.0 Radiotherapy session
0.655 0.345 0.000
G93.0 Cerebral cysts
0.654 0.346 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.654 0.346 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.653 0.347 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.652 0.347 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.652 0.347 0.000
O26.5 Maternal hypotension syndrome
0.652 0.347 0.000
O26.4 Herpes gestationis
0.652 0.347 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.652 0.347 0.000
O26.2 Pregnancy care of habitual aborter
0.652 0.347 0.000
O26.1 Low weight gain in pregnancy
0.652 0.347 0.000
O26.0 Excessive weight gain in pregnancy
0.652 0.347 0.000
Q28 Other congenital malformations of circulatory system
0.652 0.348 0.000
Q26 Congenital malformations of great veins
0.652 0.348 0.000
Q25 Congenital malformations of great arteries
0.652 0.348 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.652 0.348 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.652 0.348 0.000
R09.3 Abnormal sputum
0.652 0.348 0.000
G93.8 Other specified disorders of brain
0.652 0.348 0.000
J33.8 Other polyp of sinus
0.652 0.348 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.651 0.349 0.000
Z47 Other orthopaedic follow-up care
0.651 0.349 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.651 0.349 0.000
Q82 Other congenital malformations of skin
0.651 0.349 0.000
I09 Other rheumatic heart diseases
0.650 0.350 0.000
I06 Rheumatic aortic valve diseases
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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