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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72680133
log Bayes Factor = 12.3294
Chromosome 4   position 112,625,942  (GRCh37) Explore rs72680133 on Ensembl!
Variant rs72680133 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.992 0.008 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.990 0.010 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.989 0.011 0.000
I25.1 Atherosclerotic heart disease
0.980 0.020 0.000
I60-I69 Cerebrovascular diseases
0.980 0.020 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.978 0.022 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.971 0.029 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
E10 Insulin-dependent diabetes mellitus
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.954 0.046 0.000
I95 Hypotension
0.940 0.060 0.000
I21 Acute myocardial infarction
0.939 0.061 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.937 0.063 0.000
K55-K64 Other diseases of intestines
0.937 0.063 0.000
I73 Other peripheral vascular diseases
0.924 0.076 0.000
I60 Subarachnoid haemorrhage
0.924 0.076 0.000
A41 Other septicaemia
0.923 0.077 0.000
T81 Complications of procedures, not elsewhere classified
0.922 0.078 0.000
I71 Aortic aneurysm and dissection
0.919 0.081 0.000
Chapter VII Diseases of the eye and adnexa
0.917 0.083 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.916 0.084 0.000
S00-S09 Injuries to the head
0.914 0.086 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.910 0.090 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.907 0.093 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.906 0.094 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
A41.9 Septicaemia, unspecified
0.902 0.098 0.000
K35-K38 Diseases of appendix
0.900 0.100 0.000
S90-S99 Injuries to the ankle and foot
0.898 0.102 0.000
E10.9 Without complications
0.896 0.104 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.889 0.111 0.000
E11 Non-insulin-dependent diabetes mellitus
0.886 0.114 0.000
I25.2 Old myocardial infarction
0.886 0.114 0.000
I95.9 Hypotension, unspecified
0.878 0.122 0.000
K11 Diseases of salivary glands
0.874 0.126 0.000
I69 Sequelae of cerebrovascular disease
0.871 0.129 0.000
I74 Arterial embolism and thrombosis
0.871 0.129 0.000
Chapter V Mental and behavioural disorders
0.869 0.131 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.869 0.131 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.867 0.133 0.000
I95.1 Orthostatic hypotension
0.867 0.133 0.000
I21.9 Acute myocardial infarction, unspecified
0.866 0.134 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.863 0.137 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.862 0.138 0.000
G81 Hemiplegia
0.860 0.140 0.000
I22 Subsequent myocardial infarction
0.858 0.142 0.000
K14 Diseases of tongue
0.856 0.144 0.000
S00 Superficial injury of head
0.855 0.145 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.855 0.145 0.000
I72 Other aneurysm
0.854 0.146 0.000
H40-H42 Glaucoma
0.852 0.148 0.000
K60 Fissure and fistula of anal and rectal regions
0.850 0.150 0.000
I73.9 Peripheral vascular disease, unspecified
0.850 0.150 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.847 0.153 0.000
I24 Other acute ischaemic heart diseases
0.845 0.155 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.841 0.159 0.000
I63 Cerebral infarction
0.841 0.159 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
E20-E35 Disorders of other endocrine glands
0.834 0.166 0.000
I77 Other disorders of arteries and arterioles
0.833 0.167 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.832 0.168 0.000
K12 Stomatitis and related lesions
0.832 0.168 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.826 0.174 0.000
A00-A09 Intestinal infectious diseases
0.822 0.178 0.000
Chapter XX External causes of morbidity and mortality
0.821 0.179 0.000
G81.9 Hemiplegia, unspecified
0.820 0.180 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.818 0.182 0.000
E10.2 With renal complications
0.817 0.182 0.000
B95-B98 Bacterial, viral and other infectious agents
0.817 0.183 0.000
K08 Other disorders of teeth and supporting structures
0.814 0.186 0.000
K40-K46 Hernia
0.814 0.186 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.810 0.190 0.000
K70-K77 Diseases of liver
0.809 0.191 0.000
K37 Unspecified appendicitis
0.808 0.192 0.000
T43.2 Other and unspecified antidepressants
0.807 0.193 0.000
E50-E64 Other nutritional deficiencies
0.806 0.194 0.000
S60-S69 Injuries to the wrist and hand
0.806 0.194 0.000
H40 Glaucoma
0.805 0.195 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.801 0.199 0.000
O60-O75 Complications of labour and delivery
0.800 0.200 0.000
K10 Other diseases of jaws
0.791 0.209 0.000
K62 Other diseases of anus and rectum
0.790 0.210 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.788 0.212 0.000
K04 Diseases of pulp and periapical tissues
0.787 0.213 0.000
K01 Embedded and impacted teeth
0.786 0.213 0.000
K58 Irritable bowel syndrome
0.781 0.218 0.000
I74.5 Embolism and thrombosis of iliac artery
0.781 0.219 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.780 0.220 0.000
K43 Ventral hernia
0.779 0.221 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.779 0.221 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.778 0.222 0.000
H40.0 Glaucoma suspect
0.776 0.224 0.000
H55-H59 Other disorders of eye and adnexa
0.776 0.224 0.000
I30-I52 Other forms of heart disease
0.776 0.224 0.000
E10.3 With ophthalmic complications
0.775 0.225 0.000
K62.1 Rectal polyp
0.771 0.229 0.000
S20 Superficial injury of thorax
0.771 0.229 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.770 0.230 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.769 0.231 0.000
I63.9 Cerebral infarction, unspecified
0.763 0.237 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.763 0.237 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.762 0.238 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.761 0.239 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.761 0.239 0.000
E11.9 Without complications
0.760 0.240 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.759 0.241 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.755 0.245 0.000
K60.2 Anal fissure, unspecified
0.751 0.249 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.750 0.250 0.000
B15-B19 Viral hepatitis
0.749 0.251 0.000
E10.1 With ketoacidosis
0.747 0.253 0.000
I73.0 Raynaud's syndrome
0.747 0.253 0.000
A08 Viral and other specified intestinal infections
0.747 0.253 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.747 0.253 0.000
A80-A89 Viral infections of the central nervous system
0.746 0.254 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.745 0.255 0.000
I05-I09 Chronic rheumatic heart diseases
0.744 0.255 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.744 0.256 0.000
K14.9 Disease of tongue, unspecified
0.743 0.256 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.742 0.258 0.000
E70-E90 Metabolic disorders
0.742 0.258 0.000
G90-G99 Other disorders of the nervous system
0.742 0.258 0.000
T17 Foreign body in respiratory tract
0.741 0.259 0.000
S01 Open wound of head
0.740 0.260 0.000
K02 Dental caries
0.740 0.260 0.000
S00.9 Superficial injury of head, part unspecified
0.740 0.260 0.000
K76 Other diseases of liver
0.739 0.261 0.000
S70-S79 Injuries to the hip and thigh
0.739 0.261 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.738 0.262 0.000
K07 Dentofacial anomalies [including malocclusion]
0.738 0.262 0.000
S10-S19 Injuries to the neck
0.737 0.263 0.000
K60.3 Anal fistula
0.736 0.264 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.735 0.265 0.000
A49 Bacterial infection of unspecified site
0.734 0.266 0.000
K13 Other diseases of lip and oral mucosa
0.734 0.266 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.733 0.267 0.000
K57 Diverticular disease of intestine
0.733 0.267 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.732 0.268 0.000
S02 Fracture of skull and facial bones
0.730 0.270 0.000
K50-K52 Noninfective enteritis and colitis
0.729 0.271 0.000
I61 Intracerebral haemorrhage
0.728 0.271 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
S00.0 Superficial injury of scalp
0.727 0.273 0.000
G24 Dystonia
0.726 0.274 0.000
H10-H13 Disorders of conjunctiva
0.725 0.274 0.000
O36 Maternal care for other known or suspected foetal problems
0.725 0.275 0.000
G82 Paraplegia and tetraplegia
0.725 0.275 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.722 0.278 0.000
O63 Long labour
0.721 0.279 0.000
T40.6 Other and unspecified narcotics
0.720 0.280 0.000
T86 Failure and rejection of transplanted organs and tissues
0.719 0.280 0.000
S99 Other and unspecified injuries of ankle and foot
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B02 Zoster [herpes zoster]
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
S27 Injury of other and unspecified intrathoracic organs
0.717 0.283 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.714 0.286 0.000
A41.8 Other specified septicaemia
0.714 0.286 0.000
G83 Other paralytic syndromes
0.714 0.286 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.714 0.286 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.713 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
E11.4 With neurological complications
0.712 0.288 0.000
K35 Acute appendicitis
0.712 0.288 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.711 0.289 0.000
K11.5 Sialolithiasis
0.710 0.290 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.709 0.290 0.000
K00 Disorders of tooth development and eruption
0.709 0.290 0.000
B99-B99 Other infectious diseases
0.709 0.291 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B65-B83 Helminthiases
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.709 0.291 0.000
K08.3 Retained dental root
0.708 0.292 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.292 0.000
S92 Fracture of foot, except ankle
0.707 0.292 0.000
K11.1 Hypertrophy of salivary gland
0.707 0.293 0.000
E14 Unspecified diabetes mellitus
0.707 0.293 0.000
Chapter XIV Diseases of the genitourinary system
0.705 0.295 0.000
K09 Cysts of oral region, not elsewhere classified
0.703 0.296 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.703 0.297 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.702 0.298 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.702 0.298 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.702 0.298 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.701 0.299 0.000
I72.8 Aneurysm of other specified arteries
0.699 0.301 0.000
I77.1 Stricture of artery
0.699 0.301 0.000
I72.0 Aneurysm of carotid artery
0.697 0.303 0.000
E11.3 With ophthalmic complications
0.697 0.303 0.000
I99 Other and unspecified disorders of circulatory system
0.696 0.304 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.694 0.306 0.000
I22.8 Subsequent myocardial infarction of other sites
0.694 0.306 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.693 0.307 0.000
H52 Disorders of refraction and accommodation
0.693 0.307 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.693 0.307 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.692 0.308 0.000
N40-N51 Diseases of male genital organs
0.692 0.308 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.691 0.308 0.000
I70 Atherosclerosis
0.691 0.309 0.000
S50-S59 Injuries to the elbow and forearm
0.691 0.309 0.000
K05 Gingivitis and periodontal diseases
0.689 0.311 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.689 0.311 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.689 0.311 0.000
K11.2 Sialoadenitis
0.688 0.312 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.688 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
G80 Infantile cerebral palsy
0.687 0.313 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.686 0.314 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.685 0.315 0.000
E10.8 With unspecified complications
0.684 0.316 0.000
E10.7 With multiple complications
0.684 0.316 0.000
E10.6 With other specified complications
0.684 0.316 0.000
E10.5 With peripheral circulatory complications
0.684 0.316 0.000
E10.0 With coma
0.684 0.316 0.000
T88.4 Failed or difficult intubation
0.684 0.316 0.000
N41 Inflammatory diseases of prostate
0.684 0.316 0.000
A48 Other bacterial diseases, not elsewhere classified
0.684 0.316 0.000
A44 Bartonellosis
0.684 0.316 0.000
A43 Nocardiosis
0.684 0.316 0.000
A42 Actinomycosis
0.684 0.316 0.000
A40 Streptococcal septicaemia
0.684 0.316 0.000
A39 Meningococcal infection
0.684 0.316 0.000
A37 Whooping cough
0.684 0.316 0.000
A36 Diphtheria
0.684 0.316 0.000
A32 Listeriosis
0.684 0.316 0.000
A31 Infection due to other mycobacteria
0.684 0.316 0.000
A30 Leprosy [Hansen's disease]
0.684 0.316 0.000
A46 Erysipelas
0.684 0.316 0.000
A38 Scarlet fever
0.684 0.316 0.000
A35 Other tetanus
0.684 0.316 0.000
A34 Obstetrical tetanus
0.684 0.316 0.000
A33 Tetanus neonatorum
0.684 0.316 0.000
B35-B49 Mycoses
0.682 0.318 0.000
T18 Foreign body in alimentary tract
0.681 0.319 0.000
A02 Other Salmonella infections
0.679 0.321 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.679 0.321 0.000
N41.1 Chronic prostatitis
0.678 0.322 0.000
K61 Abscess of anal and rectal regions
0.678 0.322 0.000
G62 Other polyneuropathies
0.677 0.323 0.000
T40.2 Other opioids
0.676 0.323 0.000
T40.4 Other synthetic narcotics
0.676 0.324 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.674 0.326 0.000
O61 Failed induction of labour
0.674 0.326 0.000
I95.8 Other hypotension
0.674 0.326 0.000
I95.0 Idiopathic hypotension
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.673 0.327 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.673 0.327 0.000
S00.1 Contusion of eyelid and periocular area
0.672 0.328 0.000
S91 Open wound of ankle and foot
0.672 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.672 0.328 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.672 0.328 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.671 0.329 0.000
I62 Other nontraumatic intracranial haemorrhage
0.671 0.329 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.671 0.329 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.670 0.330 0.000
E23 Hypofunction and other disorders of pituitary gland
0.670 0.330 0.000
K14.0 Glossitis
0.670 0.330 0.000
K76.9 Liver disease, unspecified
0.667 0.333 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.667 0.333 0.000
O63.1 Prolonged second stage (of labour)
0.665 0.335 0.000
F80-F89 Disorders of psychological development
0.665 0.335 0.000
I69.3 Sequelae of cerebral infarction
0.664 0.336 0.000
S40-S49 Injuries to the shoulder and upper arm
0.663 0.336 0.000
O43 Placental disorders
0.663 0.337 0.000
I73.8 Other specified peripheral vascular diseases
0.662 0.337 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.662 0.337 0.000
I60.8 Other subarachnoid haemorrhage
0.662 0.337 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.662 0.337 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.662 0.337 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.662 0.337 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.662 0.337 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.662 0.337 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.662 0.337 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.662 0.337 0.000
G20 Parkinson's disease
0.662 0.338 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.662 0.338 0.000
A41.4 Septicaemia due to anaerobes
0.661 0.338 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.661 0.338 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.661 0.338 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.661 0.338 0.000
T81.9 Unspecified complication of procedure
0.661 0.339 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.661 0.339 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.661 0.339 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.661 0.339 0.000
S29 Other and unspecified injuries of thorax
0.660 0.340 0.000
H30-H36 Disorders of choroid and retina
0.660 0.340 0.000
I31 Other diseases of pericardium
0.660 0.340 0.000
K59 Other functional intestinal disorders
0.660 0.340 0.000
T92 Sequelae of injuries of upper limb
0.659 0.341 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.659 0.341 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.659 0.341 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.659 0.341 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.659 0.341 0.000
I71.0 Dissection of aorta [any part]
0.659 0.341 0.000
E11.5 With peripheral circulatory complications
0.659 0.341 0.000
I24.8 Other forms of acute ischaemic heart disease
0.658 0.342 0.000
K04.5 Chronic apical periodontitis
0.657 0.343 0.000
X60-X84 Intentional self-harm
0.656 0.344 0.000
S08 Traumatic amputation of part of head
0.655 0.345 0.000
S07 Crushing injury of head
0.655 0.345 0.000
S05 Injury of eye and orbit
0.655 0.345 0.000
S04 Injury of cranial nerves
0.655 0.345 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.655 0.345 0.000
E27 Other disorders of adrenal gland
0.655 0.345 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.655 0.345 0.000
H49 Paralytic strabismus
0.655 0.345 0.000
O44 Placenta praevia
0.654 0.346 0.000
I51 Complications and ill-defined descriptions of heart disease
0.652 0.348 0.000
K12.3 Oral mucositis (ulcerative)
0.652 0.348 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.652 0.348 0.000
T17.2 Foreign body in pharynx
0.651 0.349 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.650 0.349 0.000
S32 Fracture of lumbar spine and pelvis
0.650 0.350 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.650 0.350 0.000
Chapter VIII Diseases of the ear and mastoid process
0.649 0.351 0.000
O85-O92 Complications predominantly related to the puerperium
0.649 0.351 0.000
E10.4 With neurological complications
0.649 0.351 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.648 0.352 0.000
K10.8 Other specified diseases of jaws
0.648 0.352 0.000
A08.4 Viral intestinal infection, unspecified
0.648 0.352 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.648 0.352 0.000
S26 Injury of heart
0.648 0.352 0.000
S25 Injury of blood vessels of thorax
0.648 0.352 0.000
S24 Injury of nerves and spinal cord at thorax level
0.648 0.352 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.648 0.352 0.000
S21 Open wound of thorax
0.648 0.352 0.000
K12.1 Other forms of stomatitis
0.647 0.352 0.000
V80-V89 Other land transport accidents
0.647 0.353 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.647 0.353 0.000
K51 Ulcerative colitis
0.647 0.353 0.000
N60-N64 Disorders of breast
0.646 0.354 0.000
K36 Other appendicitis
0.645 0.355 0.000
B00 Herpesviral [herpes simplex] infections
0.645 0.355 0.000
B02.9 Zoster without complication
0.645 0.355 0.000
G24.9 Dystonia, unspecified
0.644 0.356 0.000
T91 Sequelae of injuries of neck and trunk
0.644 0.356 0.000
S98 Traumatic amputation of ankle and foot
0.644 0.356 0.000
S97 Crushing injury of ankle and foot
0.644 0.356 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.644 0.356 0.000
S95 Injury of blood vessels at ankle and foot level
0.644 0.356 0.000
S94 Injury of nerves at ankle and foot level
0.644 0.356 0.000
S90 Superficial injury of ankle and foot
0.644 0.356 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.643 0.357 0.000
O41 Other disorders of amniotic fluid and membranes
0.642 0.357 0.000
H55 Nystagmus and other irregular eye movements
0.642 0.358 0.000
K12.2 Cellulitis and abscess of mouth
0.642 0.358 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.642 0.358 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.642 0.358 0.000
I67 Other cerebrovascular diseases
0.641 0.359 0.000
K01.1 Impacted teeth
0.641 0.359 0.000
K38 Other diseases of appendix
0.640 0.360 0.000
E53 Deficiency of other B group vitamins
0.639 0.361 0.000
T43.9 Psychotropic drug, unspecified
0.637 0.362 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.637 0.362 0.000
T43.6 Psychostimulants with abuse potential
0.637 0.362 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.637 0.362 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.637 0.362 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.637 0.362 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.637 0.362 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.637 0.363 0.000
F60-F69 Disorders of adult personality and behaviour
0.637 0.363 0.000
T93 Sequelae of injuries of lower limb
0.637 0.363 0.000
B25-B34 Other viral diseases
0.637 0.363 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.636 0.364 0.000
T66-T78 Other and unspecified effects of external causes
0.636 0.364 0.000
K02.8 Other dental caries
0.636 0.364 0.000
E11.8 With unspecified complications
0.635 0.365 0.000
E11.7 With multiple complications
0.635 0.365 0.000
E11.6 With other specified complications
0.635 0.365 0.000
E11.1 With ketoacidosis
0.635 0.365 0.000
E11.0 With coma
0.635 0.365 0.000
S20.2 Contusion of thorax
0.635 0.365 0.000
K41 Femoral hernia
0.635 0.365 0.000
I47 Paroxysmal tachycardia
0.634 0.366 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.634 0.366 0.000
S93.1 Dislocation of toe(s)
0.633 0.367 0.000
T90 Sequelae of injuries of head
0.633 0.367 0.000
I05 Rheumatic mitral valve diseases
0.633 0.367 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.632 0.368 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.632 0.368 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.632 0.368 0.000
S60 Superficial injury of wrist and hand
0.631 0.369 0.000
I50 Heart failure
0.630 0.370 0.000
F99-F99 Unspecified mental disorder
0.630 0.370 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.629 0.371 0.000
G91 Hydrocephalus
0.628 0.371 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.628 0.372 0.000
K11.9 Disease of salivary gland, unspecified
0.627 0.373 0.000
K11.8 Other diseases of salivary glands
0.627 0.373 0.000
K11.7 Disturbances of salivary secretion
0.627 0.373 0.000
K11.6 Mucocele of salivary gland
0.627 0.373 0.000
K11.4 Fistula of salivary gland
0.627 0.373 0.000
K11.3 Abscess of salivary gland
0.627 0.373 0.000
K11.0 Atrophy of salivary gland
0.627 0.373 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.626 0.374 0.000
S01.7 Multiple open wounds of head
0.625 0.375 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.625 0.375 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.625 0.375 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.625 0.375 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.625 0.375 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.624 0.376 0.000
I74.8 Embolism and thrombosis of other arteries
0.624 0.376 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.624 0.376 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.624 0.376 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.624 0.376 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.624 0.376 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.624 0.376 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.623 0.377 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.623 0.377 0.000
F70-F79 Mental retardation
0.623 0.377 0.000
K62.9 Disease of anus and rectum, unspecified
0.623 0.377 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.622 0.378 0.000
T19 Foreign body in genito-urinary tract
0.622 0.378 0.000
T15 Foreign body on external eye
0.622 0.378 0.000
T16 Foreign body in ear
0.622 0.378 0.000
K65-K67 Diseases of peritoneum
0.621 0.379 0.000
I25.5 Ischaemic cardiomyopathy
0.621 0.379 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.621 0.379 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.619 0.380 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.619 0.381 0.000
T51 Toxic effect of alcohol
0.619 0.381 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.619 0.381 0.000
T40.8 Lysergide [LSD]
0.619 0.381 0.000
T40.7 Cannabis (derivatives)
0.619 0.381 0.000
T40.5 Cocaine
0.619 0.381 0.000
T40.3 Methadone
0.619 0.381 0.000
T40.1 Heroin
0.619 0.381 0.000
T40.0 Opium
0.619 0.381 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.618 0.382 0.000
I51.8 Other ill-defined heart diseases
0.618 0.382 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.618 0.382 0.000
F17.1 Harmful use
0.618 0.382 0.000
E55 Vitamin D deficiency
0.617 0.383 0.000
G81.1 Spastic hemiplegia
0.617 0.383 0.000
G81.0 Flaccid hemiplegia
0.617 0.383 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.617 0.383 0.000
E29 Testicular dysfunction
0.616 0.384 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.614 0.385 0.000
K14.6 Glossodynia
0.614 0.386 0.000
K14.5 Plicated tongue
0.614 0.386 0.000
K14.4 Atrophy of tongue papillae
0.614 0.386 0.000
K14.3 Hypertrophy of tongue papillae
0.614 0.386 0.000
K14.2 Median rhomboid glossitis
0.614 0.386 0.000
K14.1 Geographic tongue
0.614 0.386 0.000
I46 Cardiac arrest
0.613 0.387 0.000
S00.7 Multiple superficial injuries of head
0.613 0.387 0.000
S00.5 Superficial injury of lip and oral cavity
0.613 0.387 0.000
S00.4 Superficial injury of ear
0.613 0.387 0.000
S00.3 Superficial injury of nose
0.613 0.387 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.613 0.387 0.000
S37 Injury of urinary and pelvic organs
0.613 0.387 0.000
S36 Injury of intra-abdominal organs
0.613 0.387 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.613 0.387 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.613 0.387 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.613 0.387 0.000
S31 Open wound of abdomen, lower back and pelvis
0.613 0.387 0.000
I72.9 Aneurysm of unspecified site
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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