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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7279238
log Bayes Factor = 6.50081
Chromosome 21   position 43,092,206  (GRCh37) Explore rs7279238 on Ensembl!
Variant rs7279238 is part of Cluster X0233

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
C34 Malignant neoplasm of bronchus and lung
0.999 0.001 0.000
C79 Secondary malignant neoplasm of other sites
0.999 0.001 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.999 0.001 0.000
C34.9 Bronchus or lung, unspecified
0.997 0.003 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.994 0.006 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.009 0.991
C44 Other malignant neoplasms of skin
0.000 0.009 0.991
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.988 0.012 0.000
C44.7 Skin of lower limb, including hip
0.000 0.013 0.987
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.970 0.030 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.954 0.046 0.000
C77.1 Intrathoracic lymph nodes
0.953 0.047 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.949 0.051 0.000
C34.0 Main bronchus
0.935 0.065 0.000
C44.5 Skin of trunk
0.000 0.066 0.934
C79.2 Secondary malignant neoplasm of skin
0.918 0.082 0.000
C77.9 Lymph node, unspecified
0.915 0.085 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.913 0.087 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.910 0.090 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.909 0.091 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.901 0.099 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.900 0.100 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.100 0.900
D45 Polycythaemia vera
0.898 0.102 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.894 0.106 0.000
C80 Malignant neoplasm without specification of site
0.893 0.107 0.000
C01 Malignant neoplasm of base of tongue
0.890 0.110 0.000
C34.1 Upper lobe, bronchus or lung
0.889 0.111 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.888 0.112 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.885 0.115 0.000
C77.0 Lymph nodes of head, face and neck
0.882 0.118 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.108 0.119 0.773
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.861 0.139 0.000
C77.8 Lymph nodes of multiple regions
0.856 0.144 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.849 0.151 0.000
C77.4 Inguinal and lower limb lymph nodes
0.846 0.154 0.000
C84.5 Other and unspecified T-cell lymphomas
0.845 0.155 0.000
C85.1 B-cell lymphoma, unspecified
0.825 0.175 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.823 0.177 0.000
C10 Malignant neoplasm of oropharynx
0.820 0.180 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.812 0.188 0.000
C77.5 Intrapelvic lymph nodes
0.810 0.190 0.000
C34.2 Middle lobe, bronchus or lung
0.807 0.193 0.000
C12 Malignant neoplasm of pyriform sinus
0.803 0.197 0.000
C44.1 Skin of eyelid, including canthus
0.000 0.197 0.803
C76 Malignant neoplasm of other and ill-defined sites
0.800 0.200 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.799 0.201 0.000
C09 Malignant neoplasm of tonsil
0.794 0.206 0.000
C81 Hodgkin's disease
0.792 0.208 0.000
C34.3 Lower lobe, bronchus or lung
0.790 0.210 0.000
C91 Lymphoid leukaemia
0.784 0.216 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.781 0.219 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.779 0.221 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.775 0.225 0.000
C78.2 Secondary malignant neoplasm of pleura
0.775 0.225 0.000
D48.7 Other specified sites
0.771 0.228 0.000
C03 Malignant neoplasm of gum
0.767 0.233 0.000
C71 Malignant neoplasm of brain
0.764 0.236 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.764 0.236 0.000
D48.6 Breast
0.756 0.244 0.000
C78.7 Secondary malignant neoplasm of liver
0.750 0.250 0.000
C14.0 Pharynx, unspecified
0.750 0.250 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.742 0.258 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.738 0.262 0.000
D48.5 Skin
0.734 0.266 0.000
C95 Leukaemia of unspecified cell type
0.732 0.268 0.000
C88 Malignant immunoproliferative diseases
0.731 0.269 0.000
C80.9 Malignant neoplasm, unspecified
0.728 0.272 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.727 0.273 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.726 0.274 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.726 0.274 0.000
C04 Malignant neoplasm of floor of mouth
0.721 0.279 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.720 0.280 0.000
C43 Malignant melanoma of skin
0.026 0.281 0.693
C34.8 Overlapping lesion of bronchus and lung
0.716 0.284 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.716 0.284 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.716 0.284 0.000
C31 Malignant neoplasm of accessory sinuses
0.716 0.284 0.000
C37 Malignant neoplasm of thymus
0.716 0.284 0.000
C33 Malignant neoplasm of trachea
0.716 0.284 0.000
C11 Malignant neoplasm of nasopharynx
0.716 0.284 0.000
C69 Malignant neoplasm of eye and adnexa
0.715 0.285 0.000
C44.8 Overlapping lesion of skin
0.000 0.290 0.710
C13 Malignant neoplasm of hypopharynx
0.708 0.292 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.708 0.292 0.000
C05 Malignant neoplasm of palate
0.708 0.292 0.000
C00 Malignant neoplasm of lip
0.708 0.292 0.000
C10.9 Oropharynx, unspecified
0.700 0.300 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.698 0.302 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.695 0.304 0.000
C94 Other leukaemias of specified cell type
0.695 0.304 0.000
C93 Monocytic leukaemia
0.695 0.304 0.000
C86 Other specified types of T/NK-cell lymphoma
0.695 0.304 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.685 0.314 0.000
D48.0 Bone and articular cartilage
0.685 0.315 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.684 0.316 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.678 0.321 0.000
C81.9 Hodgkin's disease, unspecified
0.678 0.322 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.677 0.323 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.676 0.324 0.000
C02.9 Tongue, unspecified
0.671 0.329 0.000
D48.1 Connective and other soft tissue
0.669 0.331 0.000
D44.7 Aortic body and other paraganglia
0.668 0.332 0.000
D44.4 Craniopharyngeal duct
0.665 0.335 0.000
C79.6 Secondary malignant neoplasm of ovary
0.660 0.340 0.000
C02.4 Lingual tonsil
0.656 0.344 0.000
C09.9 Tonsil, unspecified
0.655 0.345 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.654 0.345 0.000
C85.0 Lymphosarcoma
0.654 0.345 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.652 0.347 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.652 0.347 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.652 0.347 0.000
C84.3 Lymphoepithelioid lymphoma
0.652 0.347 0.000
C84.2 T-zone lymphoma
0.652 0.347 0.000
C84.1 Sezary's diease
0.652 0.347 0.000
C84.0 Mycosis fungoides
0.652 0.347 0.000
D48.4 Peritoneum
0.652 0.348 0.000
D48.3 Retroperitoneum
0.652 0.348 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.652 0.348 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.350 0.650
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.648 0.351 0.000
C84.4 Peripheral T-cell lymphoma
0.648 0.352 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.647 0.353 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.646 0.354 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.644 0.355 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.356 0.644
C91.9 Lymphoid leukaemia, unspecified
0.639 0.361 0.000
C43.5 Malignant melanoma of trunk
0.004 0.361 0.635
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.638 0.362 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.635 0.365 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.634 0.365 0.000
C70 Malignant neoplasm of meninges
0.634 0.365 0.000
C71.1 Frontal lobe
0.634 0.366 0.000
C76.1 Thorax
0.634 0.366 0.000
D47.1 Chronic myeloproliferative disease
0.632 0.368 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.628 0.372 0.000
C71.8 Overlapping lesion of brain
0.621 0.379 0.000
C32 Malignant neoplasm of larynx
0.620 0.380 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.010 0.385 0.606
D44.3 Pituitary gland
0.612 0.388 0.000
C43.4 Malignant melanoma of scalp and neck
0.012 0.388 0.601
C91.1 Chronic lymphocytic leukaemia
0.610 0.390 0.000
C92 Myeloid leukaemia
0.610 0.390 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.609 0.391 0.000
C14.2 Waldeyer's ring
0.609 0.391 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.609 0.391 0.000
C03.1 Lower gum
0.608 0.392 0.000
C76.3 Pelvis
0.604 0.396 0.000
C69.2 Retina
0.602 0.398 0.000
D40.7 Other male genital organs
0.600 0.400 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.598 0.402 0.000
C06.0 Cheek mucosa
0.598 0.402 0.000
C06.9 Mouth, unspecified
0.597 0.403 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.595 0.405 0.000
D44.9 Endocrine gland, unspecified
0.590 0.410 0.000
D44.8 Pluriglandular involvement
0.590 0.410 0.000
D44.6 Carotid body
0.590 0.410 0.000
D44.5 Pineal gland
0.590 0.410 0.000
D44.2 Parathyroid gland
0.590 0.410 0.000
D44.1 Adrenal gland
0.590 0.410 0.000
D44.0 Thyroid gland
0.590 0.410 0.000
C91.0 Acute lymphoblastic leukaemia
0.588 0.412 0.000
C10.8 Overlapping lesion of oropharynx
0.588 0.412 0.000
C10.4 Branchial cleft
0.588 0.412 0.000
C10.3 Posterior wall of oropharynx
0.588 0.412 0.000
C10.2 Lateral wall of oropharynx
0.588 0.412 0.000
C10.1 Anterior surface of epiglottis
0.588 0.412 0.000
C10.0 Vallecula
0.588 0.412 0.000
C02.8 Overlapping lesion of tongue
0.582 0.417 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.582 0.417 0.000
C02.2 Ventral surface of tongue
0.582 0.417 0.000
C02.0 Dorsal surface of tongue
0.582 0.417 0.000
C71.4 Occipital lobe
0.582 0.418 0.000
C71.9 Brain, unspecified
0.579 0.421 0.000
C71.3 Parietal lobe
0.579 0.421 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.573 0.426 0.000
C76.7 Other ill-defined sites
0.573 0.426 0.000
C76.5 Lower limb
0.573 0.426 0.000
C76.4 Upper limb
0.573 0.426 0.000
C76.2 Abdomen
0.573 0.426 0.000
C76.0 Head, face and neck
0.573 0.426 0.000
C09.8 Overlapping lesion of tonsil
0.569 0.430 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.569 0.430 0.000
C09.0 Tonsillar fossa
0.569 0.430 0.000
C81.7 Other Hodgkin's disease
0.568 0.432 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.568 0.432 0.000
C81.3 Lymphocytic depletion
0.568 0.432 0.000
C81.2 Mixed cellularity
0.568 0.432 0.000
C81.0 Lymphocytic predominance
0.568 0.432 0.000
C60-C63 Malignant neoplasms of male genital organs
0.565 0.434 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.562 0.438 0.000
C91.7 Other lymphoid leukaemia
0.562 0.438 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.562 0.438 0.000
C91.5 Adult T-cell leukaemia
0.562 0.438 0.000
C91.3 Prolymphocytic leukaemia
0.562 0.438 0.000
C91.2 Subacute lymphocytic leukaemia
0.562 0.438 0.000
C95.9 Leukaemia, unspecified
0.562 0.438 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.560 0.440 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.559 0.441 0.000
C06.2 Retromolar area
0.559 0.441 0.000
C06.1 Vestibule of mouth
0.559 0.441 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.557 0.443 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.556 0.444 0.000
D46 Myelodysplastic syndromes
0.551 0.449 0.000
C03.9 Gum, unspecified
0.550 0.450 0.000
C03.0 Upper gum
0.550 0.450 0.000
C71.7 Brain stem
0.548 0.452 0.000
C71.6 Cerebellum
0.548 0.452 0.000
C71.5 Cerebral ventricle
0.548 0.452 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.548 0.452 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.548 0.452 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.006 0.454 0.540
C81.1 Nodular sclerosis
0.541 0.458 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.535 0.465 0.000
C04.9 Floor of mouth, unspecified
0.530 0.470 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.530 0.470 0.000
D40.9 Male genital organ, unspecified
0.529 0.471 0.000
D40.0 Prostate
0.529 0.471 0.000
C95.7 Other leukaemia of unspecified cell type
0.525 0.475 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.525 0.475 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.525 0.475 0.000
C95.0 Acute leukaemia of unspecified cell type
0.525 0.475 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.524 0.476 0.000
C88.7 Other malignant immunoproliferative diseases
0.524 0.476 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.524 0.476 0.000
C88.3 Immunoproliferative small intestinal disease
0.524 0.476 0.000
C88.2 Gamma heavy chain disease
0.524 0.476 0.000
C88.1 Alpha heavy chain disease
0.524 0.476 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.524 0.476 0.000
C11.9 Nasopharynx, unspecified
0.521 0.479 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.520 0.479 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.520 0.479 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.520 0.479 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.520 0.479 0.000
C04.8 Overlapping lesion of floor of mouth
0.517 0.483 0.000
C04.1 Lateral floor of mouth
0.517 0.483 0.000
C04.0 Anterior floor of mouth
0.517 0.483 0.000
C43.8 Overlapping malignant melanoma of skin
0.019 0.484 0.497
C43.1 Malignant melanoma of eyelid, including canthus
0.019 0.484 0.497
C43.0 Malignant melanoma of lip
0.019 0.484 0.497
C31.9 Accessory sinus, unspecified
0.514 0.486 0.000
C31.8 Overlapping lesion of accessory sinuses
0.514 0.486 0.000
C31.3 Sphenoidal sinus
0.514 0.486 0.000
C31.2 Frontal sinus
0.514 0.486 0.000
C31.1 Ethmoidal sinus
0.514 0.486 0.000
C31.0 Maxillary sinus
0.514 0.486 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.514 0.486 0.000
C38.4 Pleura
0.514 0.486 0.000
C38.3 Mediastinum, part unspecified
0.514 0.486 0.000
C38.2 Posterior mediastinum
0.514 0.486 0.000
C38.1 Anterior mediastinum
0.514 0.486 0.000
C38.0 Heart
0.514 0.486 0.000
C39.9 Ill-defined sites within the respiratory system
0.514 0.486 0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.514 0.486 0.000
C39.0 Upper respiratory tract, part unspecified
0.514 0.486 0.000
C11.8 Overlapping lesion of nasopharynx
0.513 0.487 0.000
C11.3 Anterior wall of nasopharynx
0.513 0.487 0.000
C11.2 Lateral wall of nasopharynx
0.513 0.487 0.000
C11.1 Posterior wall of nasopharynx
0.513 0.487 0.000
C11.0 Superior wall of nasopharynx
0.513 0.487 0.000
C44.4 Skin of scalp and neck
0.000 0.487 0.513
C69.9 Eye, unspecified
0.513 0.487 0.000
C69.8 Overlapping lesion of eye and adnexa
0.513 0.487 0.000
C69.6 Orbit
0.513 0.487 0.000
C69.5 Lachrymal gland and duct
0.513 0.487 0.000
C69.4 Ciliary body
0.513 0.487 0.000
C69.1 Cornea
0.513 0.487 0.000
C69.0 Conjunctiva
0.513 0.487 0.000
C02.1 Border of tongue
0.511 0.489 0.000
D43.0 Brain, supratentorial
0.511 0.489 0.000
C71.0 Cerebrum, except lobes and ventricles
0.511 0.489 0.000
C00.9 Lip, unspecified
0.508 0.492 0.000
C00.8 Overlapping lesion of lip
0.508 0.492 0.000
C00.6 Commissure of lip
0.508 0.492 0.000
C00.5 Lip, unspecified, inner aspect
0.508 0.492 0.000
C00.4 Lower lip, inner aspect
0.508 0.492 0.000
C00.3 Upper lip, inner aspect
0.508 0.492 0.000
C00.2 External lip, unspecified
0.508 0.492 0.000
C00.1 External lower lip
0.508 0.492 0.000
C00.0 External upper lip
0.508 0.492 0.000
C05.9 Palate, unspecified
0.508 0.492 0.000
C05.8 Overlapping lesion of palate
0.508 0.492 0.000
C05.2 Uvula
0.508 0.492 0.000
C05.1 Soft palate
0.508 0.492 0.000
C05.0 Hard palate
0.508 0.492 0.000
C08.9 Major salivary gland, unspecified
0.508 0.492 0.000
C08.8 Overlapping lesion of major salivary glands
0.508 0.492 0.000
C08.1 Sublingual gland
0.508 0.492 0.000
C08.0 Submandibular gland
0.508 0.492 0.000
C13.9 Hypopharynx, unspecified
0.508 0.492 0.000
C13.8 Overlapping lesion of hypopharynx
0.508 0.492 0.000
C13.2 Posterior wall of hypopharynx
0.508 0.492 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.508 0.492 0.000
C13.0 Postcricoid region
0.508 0.492 0.000
D40.1 Testis
0.502 0.498 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.501 0.499 0.000
C30.1 Middle ear
0.501 0.499 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.499 0.501 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.499 0.501 0.000
C86.4 Blastic NK-cell lymphoma
0.499 0.501 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.499 0.501 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.499 0.501 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.499 0.501 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.499 0.501 0.000
C93.9 Monocytic leukaemia, unspecified
0.499 0.501 0.000
C93.7 Other monocytic leukaemia
0.499 0.501 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.499 0.501 0.000
C93.2 Subacute monocytic leukaemia
0.499 0.501 0.000
C93.1 Chronic monocytic leukaemia
0.499 0.501 0.000
C93.0 Acute monocytic leukaemia
0.499 0.501 0.000
C94.7 Other specified leukaemias
0.499 0.501 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.499 0.501 0.000
C94.5 Acute myelofibrosis
0.499 0.501 0.000
C94.4 Acute panmyelosis
0.499 0.501 0.000
C94.3 Mast cell leukaemia
0.499 0.501 0.000
C94.2 Acute megakaryoblastic leukaemia
0.499 0.501 0.000
C94.1 Chronic erythraemia
0.499 0.501 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.499 0.501 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.499 0.501 0.000
C96.8 Histiocytic sarcoma
0.499 0.501 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.499 0.501 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.499 0.501 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.499 0.501 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.499 0.501 0.000
C96.3 True histiocytic lymphoma
0.499 0.501 0.000
C96.2 Malignant mast cell tumour
0.499 0.501 0.000
C96.1 Malignant histiocytosis
0.499 0.501 0.000
C96.0 Letterer-Siwe disease
0.499 0.501 0.000
C74 Malignant neoplasm of adrenal gland
0.499 0.501 0.000
C60 Malignant neoplasm of penis
0.497 0.503 0.000
C69.3 Choroid
0.496 0.503 0.000
D42.9 Meninges, unspecified
0.491 0.509 0.000
D42.1 Spinal meninges
0.491 0.509 0.000
D42.0 Cerebral meninges
0.491 0.509 0.000
C91.4 Hairy-cell leukaemia
0.488 0.511 0.000
C07 Malignant neoplasm of parotid gland
0.485 0.514 0.001
D43.9 Central nervous system, unspecified
0.484 0.515 0.000
D43.7 Other parts of central nervous system
0.484 0.515 0.000
D43.4 Spinal cord
0.484 0.515 0.000
D43.3 Cranial nerves
0.484 0.515 0.000
D43.1 Brain, infratentorial
0.484 0.515 0.000
C30.0 Nasal cavity
0.482 0.517 0.000
D47.2 Monoclonal gammopathy
0.482 0.518 0.000
C51-C58 Malignant neoplasms of female genital organs
0.481 0.519 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.020 0.519 0.461
C32.1 Supraglottis
0.479 0.520 0.000
C41.1 Mandible
0.474 0.526 0.000
C92.4 Acute promyelocytic leukaemia
0.469 0.531 0.000
C71.2 Temporal lobe
0.462 0.537 0.000
D38.6 Respiratory organ, unspecified
0.462 0.538 0.000
D38.5 Other respiratory organs
0.462 0.538 0.000
D38.4 Thymus
0.462 0.538 0.000
D38.3 Mediastinum
0.462 0.538 0.000
D38.2 Pleura
0.462 0.538 0.000
D38.0 Larynx
0.462 0.538 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.460 0.540 0.000
C49.9 Connective and soft tissue, unspecified
0.460 0.540 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.458 0.542 0.000
C46 Kaposi's sarcoma
0.458 0.542 0.000
C70.9 Meninges, unspecified
0.455 0.545 0.000
C70.1 Spinal meninges
0.455 0.545 0.000
C70.0 Cerebral meninges
0.455 0.545 0.000
C72.9 Central nervous system, unspecified
0.455 0.545 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.455 0.545 0.000
C72.5 Other and unspecified cranial nerves
0.455 0.545 0.000
C72.4 Acoustic nerve
0.455 0.545 0.000
C72.3 Optic nerve
0.455 0.545 0.000
C72.2 Olfactory nerve
0.455 0.545 0.000
C72.1 Cauda equina
0.455 0.545 0.000
C72.0 Spinal cord
0.455 0.545 0.000
D39.9 Female genital organ, unspecified
0.450 0.550 0.000
D39.7 Other female genital organs
0.450 0.550 0.000
D39.2 Placenta
0.450 0.550 0.000
D39.0 Uterus
0.450 0.550 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.448 0.552 0.000
C32.8 Overlapping lesion of larynx
0.445 0.555 0.000
C32.3 Laryngeal cartilage
0.445 0.555 0.000
C32.2 Subglottis
0.445 0.555 0.000
C75.9 Endocrine gland, unspecified
0.445 0.555 0.000
D43.2 Brain, unspecified
0.444 0.556 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.438 0.562 0.000
C92.9 Myeloid leukaemia, unspecified
0.437 0.562 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.437 0.562 0.000
C92.7 Other myeloid leukaemia
0.437 0.562 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.437 0.562 0.000
C92.5 Acute myelomonocytic leukaemia
0.437 0.562 0.000
C92.3 Myeloid sarcoma
0.437 0.562 0.000
C92.2 Subacute myeloid leukaemia
0.437 0.562 0.000
C50-C50 Malignant neoplasm of breast
0.428 0.572 0.000
C41.9 Bone and articular cartilage, unspecified
0.427 0.573 0.000
C41.8 Overlapping lesion of bone and articular cartilage
0.427 0.573 0.000
C41.4 Pelvic bones, sacrum and coccyx
0.427 0.573 0.000
C41.3 Ribs, sternum and clavicle
0.427 0.573 0.000
C41.2 Vertebral column
0.427 0.573 0.000
C41.0 Bones of skull and face
0.427 0.573 0.000
C60.9 Penis, unspecified
0.425 0.575 0.000
D38.1 Trachea, bronchus and lung
0.422 0.578 0.000
C64-C68 Malignant neoplasms of urinary tract
0.410 0.590 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.409 0.591 0.000
C90.2 Plasmacytoma, extramedullary
0.408 0.592 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.405 0.594 0.000
C60.1 Glans penis
0.403 0.597 0.000
D47.4 Osteomyelofibrosis
0.402 0.598 0.000
C90.3 Solitary plasmacytoma
0.400 0.600 0.000
C90.1 Plasma cell leukaemia
0.400 0.600 0.000
C83.7 Burkitt's tumour
0.399 0.601 0.000
C83.6 Undifferentiated (diffuse)
0.399 0.601 0.000
C83.5 Lymphoblastic (diffuse)
0.399 0.601 0.000
C83.4 Immunoblastic (diffuse)
0.399 0.601 0.000
C83.2 Mixed small and large cell (diffuse)
0.399 0.601 0.000
D46.7 Other myelodysplastic syndromes
0.395 0.605 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.395 0.605 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.395 0.605 0.000
D46.4 Refractory anaemia, unspecified
0.395 0.605 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.395 0.605 0.000
D46.2 Refractory anaemia with excess of blasts
0.395 0.605 0.000
D46.1 Refractory anaemia with sideroblasts
0.395 0.605 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.395 0.605 0.000
C83.1 Small cleaved cell (diffuse)
0.394 0.606 0.000
D39.1 Ovary
0.393 0.607 0.000
C40.9 Bone and articular cartilage of limb, unspecified
0.393 0.607 0.000
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.393 0.607 0.000
C40.3 Short bones of lower limb
0.393 0.607 0.000
C40.2 Long bones of lower limb
0.393 0.607 0.000
C40.1 Short bones of upper limb
0.393 0.607 0.000
C40.0 Scapula and long bones of upper limb
0.393 0.607 0.000
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.393 0.607 0.000
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.393 0.607 0.000
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.393 0.607 0.000
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.393 0.607 0.000
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.393 0.607 0.000
C83.3 Large cell (diffuse)
0.393 0.607 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.392 0.608 0.000
C74.9 Adrenal gland, unspecified
0.391 0.609 0.000
C32.9 Larynx, unspecified
0.381 0.618 0.000
C52 Malignant neoplasm of vagina
0.381 0.619 0.000
C75.8 Pluriglandular involvement, unspecified
0.380 0.620 0.000
C75.5 Aortic body and other paraganglia
0.380 0.620 0.000
C75.4 Carotid body
0.380 0.620 0.000
C75.3 Pineal gland
0.380 0.620 0.000
C75.2 Craniopharyngeal duct
0.380 0.620 0.000
C75.1 Pituitary gland
0.380 0.620 0.000
C75.0 Parathyroid gland
0.380 0.620 0.000
C49.3 Connective and soft tissue of thorax
0.380 0.620 0.000
C92.0 Acute myeloid leukaemia
0.380 0.620 0.000
C44.0 Skin of lip
0.000 0.620 0.379
C82.0 Small cleaved cell, follicular
0.377 0.623 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.376 0.624 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.376 0.624 0.000
C49.5 Connective and soft tissue of pelvis
0.376 0.624 0.000
C49.4 Connective and soft tissue of abdomen
0.376 0.624 0.000
C92.1 Chronic myeloid leukaemia
0.373 0.627 0.000
C32.0 Glottis
0.371 0.629 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.371 0.629 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.365 0.635 0.000
C43.9 Malignant melanoma of skin, unspecified
0.022 0.636 0.342
C82.6 Cutaneous follicle centre lymphoma
0.359 0.640 0.000
C82.5 Diffuse follicle centre lymphoma
0.359 0.640 0.000
C82.4 Follicular lymphoma grade IIIb
0.359 0.640 0.000
C82.3 Follicular lymphoma grade IIIa
0.359 0.640 0.000
C82.2 Large cell, follicular
0.359 0.640 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.359 0.641 0.000
C74.1 Medulla of adrenal gland
0.357 0.642 0.000
C74.0 Cortex of adrenal gland
0.357 0.642 0.000
C60.8 Overlapping lesion of penis
0.357 0.643 0.000
C60.2 Body of penis
0.357 0.643 0.000
C60.0 Prepuce
0.357 0.643 0.000
C62 Malignant neoplasm of testis
0.354 0.646 0.000
C49.0 Connective and soft tissue of head, face and neck
0.350 0.650 0.000
C58 Malignant neoplasm of placenta
0.345 0.655 0.000
C51 Malignant neoplasm of vulva
0.340 0.660 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.334 0.665 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.332 0.668 0.000
C46.9 Kaposi's sarcoma, unspecified
0.328 0.671 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.328 0.671 0.000
C46.7 Kaposi's sarcoma of other sites
0.328 0.671 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.328 0.671 0.000
C46.2 Kaposi's sarcoma of palate
0.328 0.671 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.328 0.671 0.000
C46.0 Kaposi's sarcoma of skin
0.328 0.671 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.328 0.671 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.328 0.671 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.328 0.671 0.000
C47.5 Peripheral nerves of pelvis
0.328 0.671 0.000
C47.4 Peripheral nerves of abdomen
0.328 0.671 0.000
C47.3 Peripheral nerves of thorax
0.328 0.671 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.328 0.671 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.328 0.671 0.000
C47.0 Peripheral nerves of head, face and neck
0.328 0.671 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.325 0.674 0.001
C48.2 Peritoneum, unspecified
0.324 0.675 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.321 0.678 0.000
C77.2 Intra-abdominal lymph nodes
0.320 0.680 0.000
C48.0 Retroperitoneum
0.319 0.681 0.000
C65 Malignant neoplasm of renal pelvis
0.315 0.685 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.313 0.687 0.000
C48.1 Specified parts of peritoneum
0.311 0.689 0.000
C78.0 Secondary malignant neoplasm of lung
0.305 0.695 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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