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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72806763
log Bayes Factor = 12.2275
Chromosome 5   position 143,010,337  (GRCh37) Explore rs72806763 on Ensembl!
Variant rs72806763 is part of Cluster X0046

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.995 0.005 0.000
M23 Internal derangement of knee
0.994 0.006 0.000
L03 Cellulitis
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.987 0.013 0.000
M50-M54 Other dorsopathies
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
M13 Other arthritis
0.979 0.021 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
L03.1 Cellulitis of other parts of limb
0.976 0.024 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.976 0.024 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.975 0.025 0.000
M54 Dorsalgia
0.970 0.030 0.000
M81 Osteoporosis without pathological fracture
0.969 0.031 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.967 0.033 0.000
M13.9 Arthritis, unspecified
0.964 0.036 0.000
M70-M79 Other soft tissue disorders
0.962 0.038 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.962 0.038 0.000
M81.9 Osteoporosis, unspecified
0.952 0.048 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.950 0.050 0.000
M25 Other joint disorders, not elsewhere classified
0.942 0.058 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.937 0.063 0.000
M54.9 Dorsalgia, unspecified
0.937 0.063 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.937 0.063 0.000
M48 Other spondylopathies
0.932 0.068 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.930 0.070 0.000
F30-F39 Mood [affective] disorders
0.922 0.078 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.919 0.081 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.918 0.082 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.917 0.083 0.000
F20 Schizophrenia
0.916 0.084 0.000
M06 Other rheumatoid arthritis
0.911 0.089 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.910 0.090 0.000
M24 Other specific joint derangements
0.905 0.095 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.902 0.098 0.000
O60-O75 Complications of labour and delivery
0.902 0.098 0.000
M48.0 Spinal stenosis
0.901 0.099 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.901 0.099 0.000
M23.3 Other meniscus derangements
0.898 0.102 0.000
S00-S09 Injuries to the head
0.894 0.106 0.000
M40-M43 Deforming dorsopathies
0.893 0.107 0.000
L05 Pilonidal cyst
0.890 0.110 0.000
L03.3 Cellulitis of trunk
0.888 0.112 0.000
S80-S89 Injuries to the knee and lower leg
0.887 0.113 0.000
M48.06 Spinal stenosis (Lumbar region)
0.884 0.116 0.000
M21 Other acquired deformities of limbs
0.884 0.116 0.000
M54.5 Low back pain
0.881 0.119 0.000
L40-L45 Papulosquamous disorders
0.880 0.120 0.000
W00-W19 Falls
0.880 0.120 0.000
L20-L30 Dermatitis and eczema
0.878 0.122 0.000
M51 Other intervertebral disk disorders
0.877 0.123 0.000
S10-S19 Injuries to the neck
0.870 0.130 0.000
Chapter XXII Codes for special purposes
0.865 0.135 0.000
M07 Psoriatic and enteropathic arthropathies
0.856 0.144 0.000
M34 Systemic sclerosis
0.855 0.145 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.852 0.148 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.845 0.155 0.000
M47 Spondylosis
0.844 0.156 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.844 0.156 0.000
M84 Disorders of continuity of bone
0.843 0.157 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.839 0.161 0.000
M79.6 Pain in limb
0.838 0.162 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.838 0.162 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.832 0.168 0.000
M23.5 Chronic instability of knee
0.832 0.168 0.000
F10.2 Dependence syndrome
0.831 0.169 0.000
F31 Bipolar affective disorder
0.830 0.170 0.000
T92 Sequelae of injuries of upper limb
0.827 0.172 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.826 0.174 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.825 0.175 0.000
F25 Schizoaffective disorders
0.824 0.176 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.823 0.177 0.000
F20.0 Paranoid schizophrenia
0.823 0.177 0.000
M65-M68 Disorders of synovium and tendon
0.820 0.180 0.000
F29 Unspecified nonorganic psychosis
0.819 0.181 0.000
L05.9 Pilonidal cyst without abscess
0.819 0.181 0.000
M25.8 Other specified joint disorders
0.818 0.182 0.000
M24.1 Other articular cartilage disorders
0.814 0.186 0.000
Chapter XIV Diseases of the genitourinary system
0.814 0.186 0.000
M10 Gout
0.813 0.187 0.000
M06.9 Rheumatoid arthritis, unspecified
0.813 0.187 0.000
F99-F99 Unspecified mental disorder
0.812 0.188 0.000
F10.1 Harmful use
0.811 0.189 0.000
L40 Psoriasis
0.811 0.189 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.810 0.190 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.808 0.192 0.000
L03.9 Cellulitis, unspecified
0.806 0.194 0.000
M79.8 Other specified soft tissue disorders
0.806 0.194 0.000
F10.3 Withdrawal state
0.806 0.194 0.000
S06 Intracranial injury
0.804 0.196 0.000
M05 Seropositive rheumatoid arthritis
0.804 0.196 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.803 0.197 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.800 0.200 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.799 0.201 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.798 0.202 0.000
F20.9 Schizophrenia, unspecified
0.798 0.202 0.000
M79.0 Rheumatism, unspecified
0.796 0.204 0.000
M54.2 Cervicalgia
0.789 0.211 0.000
M21.2 Flexion deformity
0.789 0.211 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.787 0.213 0.000
M77 Other enthesopathies
0.786 0.214 0.000
T91 Sequelae of injuries of neck and trunk
0.786 0.214 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.785 0.215 0.000
S82 Fracture of lower leg, including ankle
0.785 0.215 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.785 0.215 0.000
M13.94 Arthritis, unspecified (Hand)
0.784 0.216 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.784 0.216 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.783 0.217 0.000
M25.9 Joint disorder, unspecified
0.782 0.218 0.000
M91-M94 Chondropathies
0.781 0.219 0.000
X60-X84 Intentional self-harm
0.781 0.219 0.000
S40-S49 Injuries to the shoulder and upper arm
0.780 0.220 0.000
F17.2 Dependence syndrome
0.780 0.220 0.000
M43 Other deforming dorsopathies
0.779 0.221 0.000
M46 Other inflammatory spondylopathies
0.778 0.222 0.000
F60-F69 Disorders of adult personality and behaviour
0.778 0.222 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.777 0.223 0.000
L03.0 Cellulitis of finger and toe
0.777 0.223 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.777 0.223 0.000
N60-N64 Disorders of breast
0.777 0.223 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.776 0.224 0.000
M25.4 Effusion of joint
0.774 0.226 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.774 0.226 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.774 0.226 0.000
Y44 Agents primarily affecting blood constituents
0.774 0.226 0.000
M11 Other crystal arthropathies
0.773 0.227 0.000
S09 Other and unspecified injuries of head
0.773 0.227 0.000
M20 Acquired deformities of fingers and toes
0.768 0.232 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.767 0.233 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
M13.98 Arthritis, unspecified (Other)
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.764 0.236 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.764 0.236 0.000
M25.5 Pain in joint
0.760 0.240 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.759 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.756 0.244 0.000
M81.4 Drug-induced osteoporosis
0.755 0.245 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.755 0.245 0.000
T87 Complications peculiar to reattachment and amputation
0.754 0.245 0.000
M00-M03 Infectious arthropathies
0.754 0.246 0.000
M07.3 Other psoriatic arthropathies
0.754 0.246 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
N60 Benign mammary dysplasia
0.754 0.246 0.000
W50-W64 Exposure to animate mechanical forces
0.752 0.248 0.000
Y48 Anaesthetics and therapeutic gases
0.752 0.248 0.000
M13.93 Arthritis, unspecified (Forearm)
0.751 0.249 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
O85-O92 Complications predominantly related to the puerperium
0.750 0.250 0.000
N17-N19 Renal failure
0.749 0.251 0.000
M79.1 Myalgia
0.748 0.251 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.746 0.254 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.746 0.254 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.746 0.254 0.000
L30 Other dermatitis
0.745 0.255 0.000
M54.56 Low back pain (Lumbar region)
0.743 0.257 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.742 0.258 0.000
W19 Unspecified fall
0.742 0.258 0.000
L40.5 Arthropathic psoriasis
0.741 0.258 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.741 0.259 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.741 0.259 0.000
O24 Diabetes mellitus in pregnancy
0.741 0.259 0.000
M54.57 Low back pain (Lumbosacral region)
0.739 0.261 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.739 0.261 0.000
M70.4 Prepatellar bursitis
0.737 0.263 0.000
M67 Other disorders of synovium and tendon
0.736 0.263 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.264 0.000
M06.3 Rheumatoid nodule
0.736 0.264 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.736 0.264 0.000
M81.98 Osteoporosis, unspecified (Other)
0.734 0.265 0.000
F33 Recurrent depressive disorder
0.733 0.267 0.000
F23 Acute and transient psychotic disorders
0.733 0.267 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.732 0.268 0.000
D70 Agranulocytosis
0.731 0.269 0.000
V40-V49 Car occupant injured in transport accident
0.731 0.269 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.729 0.271 0.000
M79.69 Pain in limb (Site unspecified)
0.729 0.271 0.000
F11 Mental and behavioural disorders due to use of opioids
0.729 0.271 0.000
M21.7 Unequal limb length (acquired)
0.729 0.271 0.000
M80 Osteoporosis with pathological fracture
0.728 0.272 0.000
M60-M63 Disorders of muscles
0.728 0.272 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.727 0.273 0.000
M23.8 Other internal derangements of knee
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.274 0.000
S12 Fracture of neck
0.726 0.274 0.000
Y57 Other and unspecified drugs and medicaments
0.726 0.274 0.000
M34.8 Other forms of systemic sclerosis
0.726 0.274 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
M41 Scoliosis
0.723 0.277 0.000
T92.1 Sequelae of fracture of arm
0.721 0.279 0.000
M21.27 Flexion deformity (Ankle and foot)
0.721 0.279 0.000
O66 Other obstructed labour
0.720 0.280 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.720 0.280 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.720 0.280 0.000
N72 Inflammatory disease of cervix uteri
0.719 0.281 0.000
M51.8 Other specified intervertebral disk disorders
0.718 0.282 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
F25.9 Schizoaffective disorder, unspecified
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.716 0.284 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.716 0.284 0.000
L10-L14 Bullous disorders
0.715 0.285 0.000
L04 Acute lymphadenitis
0.714 0.286 0.000
L01 Impetigo
0.714 0.286 0.000
L00 Staphylococcal scalded skin syndrome
0.714 0.286 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.714 0.286 0.000
N18 Chronic renal failure
0.713 0.287 0.000
M54.1 Radiculopathy
0.713 0.287 0.000
M23.9 Internal derangement of knee, unspecified
0.712 0.287 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.712 0.287 0.000
M23.1 Discoid meniscus (congenital)
0.712 0.287 0.000
M23.0 Cystic meniscus
0.712 0.287 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.712 0.288 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.710 0.289 0.000
M13.0 Polyarthritis, unspecified
0.710 0.290 0.000
L20 Atopic dermatitis
0.709 0.290 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.709 0.291 0.000
M45 Ankylosing spondylitis
0.708 0.292 0.000
M83 Adult osteomalacia
0.708 0.292 0.000
M82 Osteoporosis in diseases classified elsewhere
0.708 0.292 0.000
T93 Sequelae of injuries of lower limb
0.708 0.292 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.707 0.293 0.000
M86-M90 Other osteopathies
0.706 0.294 0.000
M54.50 Low back pain (Multiple sites in spine)
0.705 0.294 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.295 0.000
M54.4 Lumbago with sciatica
0.705 0.295 0.000
M71 Other bursopathies
0.705 0.295 0.000
F32 Depressive episode
0.704 0.296 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.703 0.296 0.000
M06.4 Inflammatory polyarthropathy
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
M20.5 Other deformities of toe(s) (acquired)
0.702 0.298 0.000
M13.8 Other specified arthritis
0.702 0.298 0.000
M13.1 Monoarthritis, not elsewhere classified
0.702 0.298 0.000
O72 Postpartum haemorrhage
0.702 0.298 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
M47.8 Other spondylosis
0.701 0.299 0.000
W07 Fall involving chair
0.701 0.299 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.700 0.300 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.700 0.300 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.700 0.300 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.699 0.301 0.000
F28 Other nonorganic psychotic disorders
0.699 0.301 0.000
F24 Induced delusional disorder
0.699 0.301 0.000
F21 Schizotypal disorder
0.699 0.301 0.000
S82.2 Fracture of shaft of tibia
0.699 0.301 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.698 0.302 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
M43.1 Spondylolisthesis
0.697 0.302 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.696 0.304 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.696 0.304 0.000
O21 Excessive vomiting in pregnancy
0.696 0.304 0.000
M54.8 Other dorsalgia
0.696 0.304 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.304 0.000
N25-N29 Other disorders of kidney and ureter
0.695 0.305 0.000
M81.8 Other osteoporosis
0.695 0.305 0.000
M81.6 Localised osteoporosis [Lequesne]
0.695 0.305 0.000
M81.5 Idiopathic osteoporosis
0.695 0.305 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.695 0.305 0.000
M81.2 Osteoporosis of disuse
0.695 0.305 0.000
M81.1 Postoophorectomy osteoporosis
0.695 0.305 0.000
M81.0 Postmenopausal osteoporosis
0.695 0.305 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.695 0.305 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.694 0.306 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.694 0.306 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.694 0.306 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.694 0.306 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.694 0.306 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.694 0.306 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.694 0.306 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.694 0.306 0.000
S89 Other and unspecified injuries of lower leg
0.693 0.307 0.000
M25.57 Pain in joint (Ankle and foot)
0.692 0.308 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.691 0.309 0.000
M85 Other disorders of bone density and structure
0.691 0.309 0.000
M76 Enthesopathies of lower limb, excluding foot
0.690 0.310 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.690 0.310 0.000
M24.5 Contracture of joint
0.690 0.310 0.000
M47.9 Spondylosis, unspecified
0.688 0.312 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.688 0.312 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.687 0.313 0.000
S09.9 Unspecified injury of head
0.686 0.314 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.685 0.315 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.684 0.315 0.000
M79.7 Fibromyalgia
0.684 0.316 0.000
L27 Dermatitis due to substances taken internally
0.683 0.317 0.000
Chapter I Certain infectious and parasitic diseases
0.683 0.317 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.683 0.317 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.683 0.317 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.683 0.317 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.683 0.317 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.683 0.317 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.683 0.317 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.683 0.317 0.000
T91.3 Sequelae of injury of spinal cord
0.682 0.317 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.682 0.318 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.681 0.319 0.000
M10.9 Gout, unspecified
0.681 0.319 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.680 0.320 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.320 0.000
F99 Mental disorder, not otherwise specified
0.679 0.321 0.000
L03.2 Cellulitis of face
0.678 0.322 0.000
L40.9 Psoriasis, unspecified
0.678 0.322 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.678 0.322 0.000
O00-O08 Pregnancy with abortive outcome
0.677 0.323 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.675 0.325 0.000
M25.3 Other instability of joint
0.675 0.325 0.000
M25.2 Flail joint
0.675 0.325 0.000
M25.1 Fistula of joint
0.675 0.325 0.000
M25.0 Haemarthrosis
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.674 0.325 0.000
M79.3 Panniculitis, unspecified
0.674 0.325 0.000
M79.2 Neuralgia and neuritis, unspecified
0.674 0.325 0.000
F22 Persistent delusional disorders
0.674 0.326 0.000
M25.46 Effusion of joint (Lower leg)
0.674 0.326 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.673 0.327 0.000
O61 Failed induction of labour
0.673 0.327 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.672 0.328 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.672 0.328 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.672 0.328 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.672 0.328 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.672 0.328 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.672 0.328 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.672 0.328 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.672 0.328 0.000
W18 Other fall on same level
0.672 0.328 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.672 0.328 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.672 0.328 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.671 0.329 0.000
Y44.2 Anticoagulants
0.670 0.330 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.669 0.331 0.000
M48.9 Spondylopathy, unspecified
0.668 0.331 0.000
M48.8 Other specified spondylopathies
0.668 0.331 0.000
M48.4 Fatigue fracture of vertebra
0.668 0.331 0.000
M48.3 Traumatic spondylopathy
0.668 0.331 0.000
M48.2 Kissing spine
0.668 0.331 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.668 0.331 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.668 0.332 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.667 0.333 0.000
W10 Fall on and from stairs and steps
0.667 0.333 0.000
T98 Sequelae of other and unspecified effects of external causes
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.667 0.333 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.667 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.666 0.334 0.000
O62 Abnormalities of forces of labour
0.666 0.334 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.665 0.335 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.665 0.335 0.000
M22 Disorders of patella
0.665 0.335 0.000
U88 Agent resistant to multiple antibiotics
0.665 0.335 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.664 0.336 0.000
W17 Other fall from one level to another
0.664 0.336 0.000
T85.2 Mechanical complication of intraocular lens
0.663 0.337 0.000
O20 Haemorrhage in early pregnancy
0.662 0.338 0.000
M51.2 Other specified intervertebral disk displacement
0.661 0.339 0.000
F38 Other mood [affective] disorders
0.661 0.339 0.000
F34 Persistent mood [affective] disorders
0.661 0.339 0.000
F30 Manic episode
0.661 0.339 0.000
F39 Unspecified mood [affective] disorder
0.661 0.339 0.000
L50-L54 Urticaria and erythema
0.660 0.340 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.660 0.340 0.000
M34.9 Systemic sclerosis, unspecified
0.660 0.340 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.660 0.340 0.000
Y59 Other and unspecified vaccines and biological substances
0.659 0.341 0.000
Y58 Bacterial vaccines
0.659 0.341 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.659 0.341 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.659 0.341 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.659 0.341 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.659 0.341 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.659 0.341 0.000
M54.6 Pain in thoracic spine
0.658 0.341 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.658 0.341 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.658 0.342 0.000
M79.64 Pain in limb (Hand)
0.658 0.342 0.000
M21.0 Valgus deformity, not elsewhere classified
0.658 0.342 0.000
F10.9 Unspecified mental and behavioural disorder
0.658 0.342 0.000
F10.8 Other mental and behavioural disorders
0.658 0.342 0.000
F10.7 Residual and late-onset psychotic disorder
0.658 0.342 0.000
F10.6 Amnesic syndrome
0.658 0.342 0.000
F10.5 Psychotic disorder
0.658 0.342 0.000
F10.4 Withdrawal state with delirium
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.657 0.343 0.000
F20.8 Other schizophrenia
0.656 0.343 0.000
F20.6 Simple schizophrenia
0.656 0.343 0.000
F20.5 Residual schizophrenia
0.656 0.343 0.000
F20.4 Postschizophrenic depression
0.656 0.343 0.000
F20.3 Undifferentiated schizophrenia
0.656 0.343 0.000
F20.2 Catatonic schizophrenia
0.656 0.343 0.000
F20.1 Hebephrenic schizophrenia
0.656 0.343 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
T90 Sequelae of injuries of head
0.654 0.346 0.000
M06.8 Other specified rheumatoid arthritis
0.653 0.347 0.000
M06.2 Rheumatoid bursitis
0.653 0.347 0.000
M06.1 Adult-onset Still's disease
0.653 0.347 0.000
O28 Abnormal findings on antenatal screening of mother
0.652 0.348 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.652 0.348 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.652 0.348 0.000
O73 Retained placenta and membranes, without haemorrhage
0.651 0.349 0.000
S82.3 Fracture of lower end of tibia
0.651 0.349 0.000
N62 Hypertrophy of breast
0.651 0.349 0.000
M53 Other dorsopathies, not elsewhere classified
0.650 0.349 0.000
L30.9 Dermatitis, unspecified
0.650 0.350 0.000
M24.9 Joint derangement, unspecified
0.649 0.351 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.649 0.351 0.000
M24.7 Protrusio acetabuli
0.649 0.351 0.000
M24.6 Ankylosis of joint
0.649 0.351 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.649 0.351 0.000
M24.2 Disorder of ligament
0.649 0.351 0.000
M24.0 Loose body in joint
0.649 0.351 0.000
S82.6 Fracture of lateral malleolus
0.649 0.351 0.000
M20.2 Hallux rigidus
0.648 0.352 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.648 0.352 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.647 0.352 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.647 0.353 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.647 0.353 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.647 0.353 0.000
T83.2 Mechanical complication of graft of urinary organ
0.647 0.353 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.647 0.353 0.000
O74 Complications of anaesthesia during labour and delivery
0.646 0.353 0.000
O71 Other obstetric trauma
0.646 0.353 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.646 0.353 0.000
O60 Preterm delivery
0.646 0.353 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.646 0.354 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.646 0.354 0.000
M48.04 Spinal stenosis (Thoracic region)
0.646 0.354 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.646 0.354 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.646 0.354 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
T36 Poisoning by systemic antibiotics
0.646 0.354 0.000
D75 Other diseases of blood and blood-forming organs
0.644 0.355 0.000
M23.37 Other meniscus derangements-Capsular lig
0.644 0.356 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.644 0.356 0.000
M48.09 Spinal stenosis (Site unspecified)
0.643 0.357 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.642 0.358 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.641 0.359 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.641 0.359 0.000
S08 Traumatic amputation of part of head
0.641 0.359 0.000
S07 Crushing injury of head
0.641 0.359 0.000
S05 Injury of eye and orbit
0.641 0.359 0.000
S04 Injury of cranial nerves
0.641 0.359 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.641 0.359 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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