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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72869965
log Bayes Factor = 16.5238
Chromosome 11   position 16,333,060  (GRCh37) Explore rs72869965 on Ensembl!
Variant rs72869965 is part of Cluster X0182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
R42 Dizziness and giddiness
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
I60-I69 Cerebrovascular diseases
0.995 0.005 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
R30-R39 Symptoms and signs involving the urinary system
0.990 0.010 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.989 0.011 0.000
R50-R69 General symptoms and signs
0.989 0.011 0.000
M54 Dorsalgia
0.988 0.012 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.986 0.014 0.000
M20 Acquired deformities of fingers and toes
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
R51 Headache
0.979 0.021 0.000
C15 Malignant neoplasm of oesophagus
0.976 0.024 0.000
R31 Unspecified haematuria
0.976 0.024 0.000
H65-H75 Diseases of middle ear and mastoid
0.966 0.034 0.000
I67 Other cerebrovascular diseases
0.961 0.039 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.960 0.040 0.000
C20 Malignant neoplasm of rectum
0.957 0.043 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.956 0.044 0.000
Chapter X Diseases of the respiratory system
0.949 0.051 0.000
R56 Convulsions, not elsewhere classified
0.946 0.054 0.000
I73 Other peripheral vascular diseases
0.945 0.055 0.000
M54.3 Sciatica
0.944 0.056 0.000
R55 Syncope and collapse
0.943 0.057 0.000
M45-M49 Spondylopathies
0.940 0.060 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.927 0.073 0.000
C15.5 Lower third of oesophagus
0.927 0.073 0.000
J30-J39 Other diseases of upper respiratory tract
0.918 0.082 0.000
R56.8 Other and unspecified convulsions
0.915 0.085 0.000
R41.0 Disorientation, unspecified
0.908 0.092 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.907 0.093 0.000
M20.2 Hallux rigidus
0.905 0.095 0.000
C16 Malignant neoplasm of stomach
0.905 0.095 0.000
I21 Acute myocardial infarction
0.904 0.096 0.000
J90-J94 Other diseases of pleura
0.902 0.098 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.897 0.103 0.000
I69 Sequelae of cerebrovascular disease
0.895 0.105 0.000
M20.4 Other hammer toe(s) (acquired)
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.894 0.106 0.000
I73.0 Raynaud's syndrome
0.892 0.108 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.891 0.109 0.000
M54.36 Sciatica (Lumbar region)
0.890 0.110 0.000
R41.2 Retrograde amnesia
0.889 0.111 0.000
Y40 Systemic antibiotics
0.888 0.112 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.886 0.114 0.000
I63 Cerebral infarction
0.885 0.115 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.883 0.117 0.000
H72 Perforation of tympanic membrane
0.883 0.117 0.000
I67.8 Other specified cerebrovascular diseases
0.881 0.119 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.879 0.121 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.879 0.121 0.000
Y52 Agents primarily affecting the cardiovascular system
0.879 0.121 0.000
I77 Other disorders of arteries and arterioles
0.878 0.122 0.000
M54.5 Low back pain
0.876 0.124 0.000
M20.5 Other deformities of toe(s) (acquired)
0.874 0.126 0.000
M47 Spondylosis
0.872 0.128 0.000
R32 Unspecified urinary incontinence
0.868 0.132 0.000
C15.9 Oesophagus, unspecified
0.868 0.132 0.000
J93 Pneumothorax
0.868 0.132 0.000
M54.9 Dorsalgia, unspecified
0.862 0.138 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.862 0.138 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.858 0.142 0.000
C64-C68 Malignant neoplasms of urinary tract
0.852 0.148 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.852 0.148 0.000
M45 Ankylosing spondylitis
0.851 0.149 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.849 0.151 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.846 0.154 0.000
M34 Systemic sclerosis
0.846 0.154 0.000
Y86 Sequelae of other accidents
0.845 0.155 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.843 0.157 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.842 0.158 0.000
R07 Pain in throat and chest
0.839 0.161 0.000
M91-M94 Chondropathies
0.836 0.164 0.000
H65 Nonsuppurative otitis media
0.835 0.165 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.831 0.169 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.828 0.172 0.000
I74 Arterial embolism and thrombosis
0.828 0.172 0.000
M54.2 Cervicalgia
0.827 0.173 0.000
C71 Malignant neoplasm of brain
0.826 0.174 0.000
M54.56 Low back pain (Lumbar region)
0.825 0.175 0.000
I05-I09 Chronic rheumatic heart diseases
0.824 0.176 0.000
R52 Pain, not elsewhere classified
0.822 0.178 0.000
W20-W49 Exposure to inanimate mechanical forces
0.819 0.181 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.817 0.183 0.000
J36 Peritonsillar abscess
0.816 0.184 0.000
M22 Disorders of patella
0.816 0.184 0.000
Y57 Other and unspecified drugs and medicaments
0.816 0.184 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.815 0.185 0.000
H60-H62 Diseases of external ear
0.815 0.185 0.000
M54.1 Radiculopathy
0.813 0.187 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.812 0.188 0.000
I21.9 Acute myocardial infarction, unspecified
0.811 0.189 0.000
M40-M43 Deforming dorsopathies
0.810 0.190 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.810 0.190 0.000
J33 Nasal polyp
0.805 0.195 0.000
C16.0 Cardia
0.804 0.196 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.802 0.198 0.000
M24 Other specific joint derangements
0.802 0.198 0.000
H73 Other disorders of tympanic membrane
0.802 0.198 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.801 0.199 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.801 0.199 0.000
H71 Cholesteatoma of middle ear
0.800 0.200 0.000
I10-I15 Hypertensive diseases
0.800 0.200 0.000
R34 Anuria and oliguria
0.798 0.202 0.000
J93.1 Other spontaneous pneumothorax
0.798 0.202 0.000
M31 Other necrotising vasculopathies
0.798 0.202 0.000
R25 Abnormal involuntary movements
0.798 0.202 0.000
M21 Other acquired deformities of limbs
0.797 0.203 0.000
I65.2 Occlusion and stenosis of carotid artery
0.796 0.204 0.000
I25.2 Old myocardial infarction
0.796 0.204 0.000
M54.8 Other dorsalgia
0.793 0.207 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.793 0.207 0.000
J35 Chronic diseases of tonsils and adenoids
0.793 0.207 0.000
S60-S69 Injuries to the wrist and hand
0.792 0.208 0.000
M86-M90 Other osteopathies
0.790 0.210 0.000
M35 Other systemic involvement of connective tissue
0.789 0.211 0.000
H72.0 Central perforation of tympanic membrane
0.788 0.212 0.000
I25.4 Coronary artery aneurysm
0.788 0.212 0.000
M47.9 Spondylosis, unspecified
0.788 0.212 0.000
M47.8 Other spondylosis
0.787 0.213 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.787 0.213 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.787 0.213 0.000
R30 Pain associated with micturition
0.785 0.215 0.000
R07.4 Chest pain, unspecified
0.785 0.215 0.000
I67.2 Cerebral atherosclerosis
0.784 0.216 0.000
R47-R49 Symptoms and signs involving speech and voice
0.783 0.217 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.782 0.218 0.000
R58 Haemorrhage, not elsewhere classified
0.779 0.221 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.778 0.222 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.778 0.222 0.000
I25.3 Aneurysm of heart
0.777 0.223 0.000
V80-V89 Other land transport accidents
0.776 0.224 0.000
I67.1 Cerebral aneurysm, nonruptured
0.771 0.229 0.000
C51-C58 Malignant neoplasms of female genital organs
0.771 0.229 0.000
C15.4 Middle third of oesophagus
0.769 0.231 0.000
J33.0 Polyp of nasal cavity
0.768 0.232 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.768 0.232 0.000
J93.9 Pneumothorax, unspecified
0.768 0.232 0.000
I73.9 Peripheral vascular disease, unspecified
0.766 0.234 0.000
M54.4 Lumbago with sciatica
0.766 0.234 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.766 0.234 0.000
M53 Other dorsopathies, not elsewhere classified
0.766 0.234 0.000
R46 Symptoms and signs involving appearance and behaviour
0.765 0.235 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.764 0.236 0.000
I60 Subarachnoid haemorrhage
0.764 0.236 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.764 0.236 0.000
I95 Hypotension
0.764 0.236 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.763 0.236 0.000
Y40.8 Other systemic antibiotics
0.763 0.237 0.000
Y42.7 Androgens and anabolic congeners
0.763 0.237 0.000
C17 Malignant neoplasm of small intestine
0.763 0.237 0.000
M20.1 Hallux valgus (acquired)
0.760 0.240 0.000
M54.37 Sciatica (Lumbosacral region)
0.759 0.241 0.000
R07.3 Other chest pain
0.757 0.243 0.000
H66 Suppurative and unspecified otitis media
0.757 0.243 0.000
R29.6 Tendency to fall, not elsewhere classified
0.757 0.243 0.000
S40-S49 Injuries to the shoulder and upper arm
0.755 0.245 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.755 0.245 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.754 0.246 0.000
X50-X57 Overexertion, travel and privation
0.754 0.246 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.750 0.250 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.750 0.250 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.750 0.250 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.748 0.252 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.748 0.252 0.000
M20.0 Deformity of finger(s)
0.748 0.252 0.000
J30 Vasomotor and allergic rhinitis
0.745 0.255 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.745 0.255 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.744 0.256 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.743 0.257 0.000
Q50-Q56 Congenital malformations of genital organs
0.742 0.258 0.000
W50-W64 Exposure to animate mechanical forces
0.741 0.259 0.000
I73.8 Other specified peripheral vascular diseases
0.740 0.259 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.740 0.260 0.000
V40-V49 Car occupant injured in transport accident
0.740 0.260 0.000
R03.1 Nonspecific low blood-pressure reading
0.739 0.261 0.000
S62 Fracture at wrist and hand level
0.738 0.262 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.738 0.262 0.000
R52.1 Chronic intractable pain
0.737 0.263 0.000
I12 Hypertensive renal disease
0.737 0.263 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.735 0.265 0.000
Chapter XXII Codes for special purposes
0.731 0.269 0.000
H69 Other disorders of Eustachian tube
0.730 0.269 0.000
I77.1 Stricture of artery
0.730 0.270 0.000
C10 Malignant neoplasm of oropharynx
0.729 0.271 0.000
Q80-Q89 Other congenital malformations
0.728 0.272 0.000
I27 Other pulmonary heart diseases
0.727 0.273 0.000
I22 Subsequent myocardial infarction
0.727 0.273 0.000
I08 Multiple valve diseases
0.726 0.274 0.000
J09-J18 Influenza and pneumonia
0.726 0.274 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.725 0.274 0.000
C16.5 Lesser curvature of stomach, unspecified
0.725 0.275 0.000
C79 Secondary malignant neoplasm of other sites
0.723 0.277 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.722 0.278 0.000
C71.9 Brain, unspecified
0.722 0.278 0.000
I67.9 Cerebrovascular disease, unspecified
0.721 0.279 0.000
M54.29 Cervicalgia-Site unspe
0.721 0.279 0.000
C09 Malignant neoplasm of tonsil
0.720 0.280 0.000
D73 Diseases of spleen
0.720 0.280 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.719 0.281 0.000
R50 Fever of unknown origin
0.719 0.281 0.000
J90 Pleural effusion, not elsewhere classified
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.282 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R43 Disturbances of smell and taste
0.717 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
C23 Malignant neoplasm of gallbladder
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
I77.8 Other specified disorders of arteries and arterioles
0.712 0.288 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.711 0.289 0.000
M47.86 Other spondylosis (Lumbar region)
0.711 0.289 0.000
H60 Otitis externa
0.711 0.289 0.000
R36 Urethral discharge
0.710 0.290 0.000
R35 Polyuria
0.710 0.290 0.000
J37 Chronic laryngitis and laryngotracheitis
0.709 0.291 0.000
Y59 Other and unspecified vaccines and biological substances
0.709 0.291 0.000
Y58 Bacterial vaccines
0.709 0.291 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.709 0.291 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.709 0.291 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.709 0.291 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.709 0.291 0.000
Y48 Anaesthetics and therapeutic gases
0.709 0.291 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.709 0.291 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.709 0.291 0.000
R62 Lack of expected normal physiological development
0.709 0.291 0.000
R64 Cachexia
0.709 0.291 0.000
J94 Other pleural conditions
0.708 0.292 0.000
M54.0 Panniculitis affecting regions of neck and back
0.708 0.292 0.000
Y60.0 During surgical operation
0.708 0.292 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.707 0.293 0.000
R41.1 Anterograde amnesia
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.705 0.295 0.000
Y44 Agents primarily affecting blood constituents
0.704 0.296 0.000
I69.3 Sequelae of cerebral infarction
0.703 0.297 0.000
D00-D09 In situ neoplasms
0.703 0.297 0.000
D48.5 Skin
0.702 0.297 0.000
D40.0 Prostate
0.702 0.298 0.000
C15.8 Overlapping lesion of oesophagus
0.700 0.300 0.000
C15.3 Upper third of oesophagus
0.700 0.300 0.000
C15.2 Abdominal part of oesophagus
0.700 0.300 0.000
C15.1 Thoracic part of oesophagus
0.700 0.300 0.000
C15.0 Cervical part of oesophagus
0.700 0.300 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.699 0.301 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.698 0.302 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.694 0.306 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.694 0.306 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.693 0.307 0.000
H70 Mastoiditis and related conditions
0.693 0.307 0.000
H68 Eustachian salpingitis and obstruction
0.693 0.307 0.000
H67 Otitis media in diseases classified elsewhere
0.693 0.307 0.000
R05 Cough
0.692 0.308 0.000
J31.0 Chronic rhinitis
0.692 0.308 0.000
D43.2 Brain, unspecified
0.692 0.308 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.691 0.309 0.000
M34.8 Other forms of systemic sclerosis
0.691 0.309 0.000
M94 Other disorders of cartilage
0.691 0.309 0.000
R02 Gangrene, not elsewhere classified
0.690 0.310 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.689 0.311 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.689 0.311 0.000
I67.5 Moyamoya disease
0.689 0.311 0.000
I67.4 Hypertensive encephalopathy
0.689 0.311 0.000
I67.3 Progressive vascular leukoencephalopathy
0.689 0.311 0.000
D73.0 Hyposplenism
0.689 0.311 0.000
M31.3 Wegener's granulomatosis
0.688 0.312 0.000
R60 Oedema, not elsewhere classified
0.688 0.312 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.686 0.314 0.000
C07 Malignant neoplasm of parotid gland
0.686 0.314 0.000
Y54.3 Benzothiadiazine derivatives
0.686 0.314 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.686 0.314 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.686 0.314 0.000
I12.0 Hypertensive renal disease with renal failure
0.686 0.314 0.000
C25 Malignant neoplasm of pancreas
0.685 0.315 0.000
H73.8 Other specified disorders of tympanic membrane
0.684 0.316 0.000
R53 Malaise and fatigue
0.684 0.316 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.683 0.317 0.000
M86 Osteomyelitis
0.683 0.317 0.000
M34.9 Systemic sclerosis, unspecified
0.682 0.318 0.000
H65.2 Chronic serous otitis media
0.682 0.318 0.000
Y40.0 Penicillins
0.682 0.318 0.000
X60-X84 Intentional self-harm
0.681 0.319 0.000
M65-M68 Disorders of synovium and tendon
0.681 0.319 0.000
S62.6 Fracture of other finger
0.680 0.320 0.000
R30.0 Dysuria
0.680 0.320 0.000
M54.6 Pain in thoracic spine
0.679 0.321 0.000
W44 Foreign body entering into or through eye or natural orifice
0.679 0.321 0.000
I72 Other aneurysm
0.679 0.321 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.678 0.322 0.000
R56.0 Febrile convulsions
0.678 0.322 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.678 0.322 0.000
C91 Lymphoid leukaemia
0.677 0.323 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.677 0.323 0.000
H65.3 Chronic mucoid otitis media
0.677 0.323 0.000
M54.35 Sciatica (Thoracolumbar region)
0.677 0.323 0.000
M54.34 Sciatica-Thoracic
0.677 0.323 0.000
M54.33 Sciatica-Cervicothoracic
0.677 0.323 0.000
M54.32 Sciatica-Cervical
0.677 0.323 0.000
M54.31 Sciatica-Occipit-atl-axl
0.677 0.323 0.000
M54.30 Sciatica (Multiple sites in spine)
0.677 0.323 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.323 0.000
C67 Malignant neoplasm of bladder
0.677 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.676 0.324 0.000
Y57.8 Other drugs and medicaments
0.676 0.324 0.000
M20.3 Other deformity of hallux (acquired)
0.675 0.325 0.000
C71.8 Overlapping lesion of brain
0.674 0.326 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.674 0.326 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.326 0.000
J32 Chronic sinusitis
0.674 0.326 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.673 0.327 0.000
M22.3 Other derangements of patella
0.673 0.327 0.000
M35.0 Sicca syndrome [Sjogren]
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.672 0.328 0.000
J00-J06 Acute upper respiratory infections
0.672 0.328 0.000
I95.2 Hypotension due to drugs
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.669 0.331 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.668 0.331 0.000
M54.16 Radiculopathy (Lumbar region)
0.668 0.332 0.000
I26 Pulmonary embolism
0.667 0.333 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.667 0.333 0.000
H90-H95 Other disorders of ear
0.667 0.333 0.000
C16.9 Stomach, unspecified
0.667 0.333 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.667 0.333 0.000
I24 Other acute ischaemic heart diseases
0.667 0.333 0.000
M54.57 Low back pain (Lumbosacral region)
0.666 0.334 0.000
D40.1 Testis
0.666 0.334 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.665 0.335 0.000
R29.4 Clicking hip
0.665 0.335 0.000
R29.3 Abnormal posture
0.665 0.335 0.000
R29.2 Abnormal reflex
0.665 0.335 0.000
R29.1 Meningismus
0.665 0.335 0.000
R29.0 Tetany
0.665 0.335 0.000
I70 Atherosclerosis
0.664 0.336 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.664 0.336 0.000
S64 Injury of nerves at wrist and hand level
0.664 0.336 0.000
C92 Myeloid leukaemia
0.664 0.336 0.000
W22 Striking against or struck by other objects
0.664 0.336 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.663 0.337 0.000
M54.55 Low back pain (Thoracolumbar region)
0.662 0.337 0.000
S69 Other and unspecified injuries of wrist and hand
0.661 0.339 0.000
D60-D64 Aplastic and other anaemias
0.661 0.339 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.661 0.339 0.000
J31.2 Chronic pharyngitis
0.660 0.340 0.000
R26 Abnormalities of gait and mobility
0.659 0.341 0.000
Y60.8 During other surgical and medical care
0.658 0.342 0.000
J30.3 Other allergic rhinitis
0.657 0.343 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.656 0.344 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
R25.2 Cramp and spasm
0.655 0.345 0.000
M24.0 Loose body in joint
0.655 0.345 0.000
M21.4 Flat foot [pes planus] (acquired)
0.655 0.345 0.000
R47 Speech disturbances, not elsewhere classified
0.655 0.345 0.000
C80 Malignant neoplasm without specification of site
0.654 0.346 0.000
H60.9 Otitis externa, unspecified
0.654 0.346 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.653 0.347 0.000
M54.89 Other dorsalgia (Site unspecified)
0.653 0.347 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.653 0.347 0.000
Y52.1 Calcium-channel blockers
0.653 0.347 0.000
D80-D89 Certain disorders involving the immune mechanism
0.653 0.347 0.000
J93.8 Other pneumothorax
0.652 0.348 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.652 0.348 0.000
M43 Other deforming dorsopathies
0.650 0.350 0.000
C71.2 Temporal lobe
0.650 0.350 0.000
C16.8 Overlapping lesion of stomach
0.649 0.351 0.000
C16.6 Greater curvature of stomach, unspecified
0.649 0.351 0.000
C16.4 Pylorus
0.649 0.351 0.000
C16.3 Pyloric antrum
0.649 0.351 0.000
C16.2 Body of stomach
0.649 0.351 0.000
C16.1 Fundus of stomach
0.649 0.351 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.649 0.351 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.649 0.351 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.648 0.352 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.648 0.352 0.000
M92 Other juvenile osteochondrosis
0.648 0.352 0.000
I99 Other and unspecified disorders of circulatory system
0.648 0.352 0.000
S50-S59 Injuries to the elbow and forearm
0.648 0.352 0.000
R52.9 Pain, unspecified
0.648 0.352 0.000
H74 Other disorders of middle ear and mastoid
0.647 0.353 0.000
S62.60 Fracture of other finger (closed)
0.644 0.356 0.000
H80-H83 Diseases of inner ear
0.643 0.356 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.643 0.357 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.642 0.358 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.642 0.358 0.000
S10-S19 Injuries to the neck
0.642 0.358 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.641 0.359 0.000
Q35-Q37 Cleft lip and cleft palate
0.641 0.359 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.641 0.359 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.641 0.359 0.000
C70 Malignant neoplasm of meninges
0.641 0.359 0.000
S90-S99 Injuries to the ankle and foot
0.641 0.359 0.000
Chapter VI Diseases of the nervous system
0.640 0.360 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.639 0.360 0.000
C66 Malignant neoplasm of ureter
0.639 0.361 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.639 0.361 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.639 0.361 0.000
C60-C63 Malignant neoplasms of male genital organs
0.639 0.361 0.000
D46 Myelodysplastic syndromes
0.638 0.362 0.000
S42 Fracture of shoulder and upper arm
0.638 0.362 0.000
I62 Other nontraumatic intracranial haemorrhage
0.638 0.362 0.000
D41.0 Kidney
0.638 0.362 0.000
D47.4 Osteomyelofibrosis
0.638 0.362 0.000
C81 Hodgkin's disease
0.637 0.363 0.000
Y40.7 Antifungal antibiotics, systemically used
0.636 0.364 0.000
Y40.6 Rifamycins
0.636 0.364 0.000
Y40.5 Aminoglycosides
0.636 0.364 0.000
Y40.4 Tetracyclines
0.636 0.364 0.000
Y40.3 Macrolides
0.636 0.364 0.000
Y40.2 Chloramphenicol group
0.636 0.364 0.000
Y89 Sequelae of other external causes
0.635 0.364 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.635 0.364 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.635 0.365 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.635 0.365 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.635 0.365 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.635 0.365 0.000
D48.7 Other specified sites
0.634 0.366 0.000
J35.2 Hypertrophy of adenoids
0.634 0.366 0.000
M22.2 Patellofemoral disorders
0.634 0.366 0.000
I71 Aortic aneurysm and dissection
0.634 0.366 0.000
R68 Other general symptoms and signs
0.633 0.367 0.000
Y65 Other misadventures during surgical and medical care
0.633 0.367 0.000
Y64 Contaminated medical or biological substances
0.633 0.367 0.000
Y63 Failure in dosage during surgical and medical care
0.633 0.367 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.633 0.367 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.633 0.367 0.000
Y69 Unspecified misadventure during surgical and medical care
0.633 0.367 0.000
Y66 Nonadministration of surgical and medical care
0.633 0.367 0.000
H72.2 Other marginal perforations of tympanic membrane
0.633 0.367 0.000
H72.1 Attic perforation of tympanic membrane
0.633 0.367 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.632 0.368 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.630 0.369 0.000
C13 Malignant neoplasm of hypopharynx
0.630 0.369 0.000
C11 Malignant neoplasm of nasopharynx
0.630 0.369 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.630 0.369 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.630 0.369 0.000
C05 Malignant neoplasm of palate
0.630 0.369 0.000
C04 Malignant neoplasm of floor of mouth
0.630 0.369 0.000
C03 Malignant neoplasm of gum
0.630 0.369 0.000
C00 Malignant neoplasm of lip
0.630 0.369 0.000
C12 Malignant neoplasm of pyriform sinus
0.630 0.369 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.630 0.369 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.630 0.369 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.630 0.369 0.000
I65.1 Occlusion and stenosis of basilar artery
0.630 0.369 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.630 0.369 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.630 0.370 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.630 0.370 0.000
Y52.7 Peripheral vasodilators
0.630 0.370 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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