TreeWAS – Variant ID: rs72971657

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000
I10 Essential (primary) hypertension	0.999	0.001
M25 Other joint disorders, not elsewhere classified	0.999	0.001
Z53 Persons encountering health services for specifie procedures, not carried out	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.998	0.002
M23 Internal derangement of knee	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
N30-N39 Other diseases of urinary system	0.995	0.005
I20 Angina pectoris	0.993	0.007
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.992	0.008
Z87 Personal history of other diseases and conditions	0.991	0.009
Z53.0 Procedure not carried out because of contraindication	0.991	0.009
M15-M19 Arthrosis	0.989	0.011
N17-N19 Renal failure	0.988	0.012
M17 Gonarthrosis [arthrosis of knee]	0.986	0.014
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.985	0.015
M25.5 Pain in joint	0.985	0.015
N18 Chronic renal failure	0.985	0.015
I25.9 Chronic ischaemic heart disease, unspecified	0.985	0.015
Chapter I Certain infectious and parasitic diseases	0.984	0.016
M17.9 Gonarthrosis, unspecified	0.984	0.016
M23.3 Other meniscus derangements	0.983	0.017
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.981	0.019
N35 Urethral stricture	0.980	0.020
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.980	0.020
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.977	0.023
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.976	0.024
M45-M49 Spondylopathies	0.974	0.026
Chapter XI Diseases of the digestive system	0.973	0.027
I25.2 Old myocardial infarction	0.973	0.027
Z91 Personal history of risk-factors, not elsewhere classified	0.972	0.028
N35.9 Urethral stricture, unspecified	0.970	0.030
Chapter XX External causes of morbidity and mortality	0.968	0.032
I20.9 Angina pectoris, unspecified	0.966	0.034
N18.3 Chronic kidney disease, stage 3	0.965	0.035
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.964	0.036
T36-T50 Poisoning by drugs, medicaments and biological substances	0.962	0.038
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.961	0.039
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.957	0.043
E70-E90 Metabolic disorders	0.956	0.044
Z88.5 Personal history of allergy to narcotic agent	0.954	0.046
Z87.1 Personal history of diseases of the digestive system	0.954	0.046
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.952	0.048
T85 Complications of other internal prosthetic devices, implants and grafts	0.950	0.050
M47 Spondylosis	0.948	0.052
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.947	0.053
E78.5 Hyperlipidaemia, unspecified	0.945	0.055
I70-I79 Diseases of arteries, arterioles and capillaries	0.943	0.057
M23.30 Other meniscus derangements (Multiple sites)	0.943	0.057
Z53.9 Procedure not carried out, unspecified reason	0.942	0.058
Z96 Presence of other functional implants	0.942	0.058
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.942	0.058
Z89 Acquired absence of limb	0.941	0.059
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.937	0.063
Z60 Problems related to social environment	0.937	0.063
Z45 Adjustment and management of implanted device	0.936	0.064
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.935	0.065
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.934	0.066
Chapter II Neoplasms	0.934	0.066
M25.4 Effusion of joint	0.932	0.068
R00 Abnormalities of heart beat	0.932	0.068
M23.2 Derangement of meniscus due to old tear or injury	0.930	0.070
K55-K64 Other diseases of intestines	0.930	0.070
E10-E14 Diabetes mellitus	0.929	0.071
M65-M68 Disorders of synovium and tendon	0.929	0.071
I25.5 Ischaemic cardiomyopathy	0.927	0.073
Z96.6 Presence of orthopaedic joint implants	0.927	0.073
I21 Acute myocardial infarction	0.926	0.074
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.925	0.075
M25.56 Pain in joint (Lower leg)	0.924	0.076
Z42 Follow-up care involving plastic surgery	0.922	0.078
M25.57 Pain in joint (Ankle and foot)	0.921	0.079
Z88.6 Personal history of allergy to analgesic agent	0.917	0.083
Z85 Personal history of malignant neoplasm	0.917	0.083
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.915	0.085
Z50 Care involving use of rehabilitation procedures	0.912	0.088
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.909	0.091
Chapter VII Diseases of the eye and adnexa	0.909	0.091
Chapter VIII Diseases of the ear and mastoid process	0.908	0.092
T66-T78 Other and unspecified effects of external causes	0.908	0.092
I20.1 Angina pectoris with documented spasm	0.908	0.092
Z60.2 Living alone	0.907	0.093
T93 Sequelae of injuries of lower limb	0.907	0.093
C64-C68 Malignant neoplasms of urinary tract	0.906	0.094
M70-M79 Other soft tissue disorders	0.906	0.094
R00.2 Palpitations	0.905	0.095
I25.8 Other forms of chronic ischaemic heart disease	0.904	0.096
S00-S09 Injuries to the head	0.903	0.097
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.900	0.100
Chapter V Mental and behavioural disorders	0.899	0.101
Z22 Carrier of infectious disease	0.899	0.101
R50-R69 General symptoms and signs	0.898	0.102
M35 Other systemic involvement of connective tissue	0.897	0.103
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.897	0.103
R63 Symptoms and signs concerning food and fluid intake	0.896	0.104
C67 Malignant neoplasm of bladder	0.896	0.104
R63.4 Abnormal weight loss	0.895	0.105
Z85.5 Personal history of malignant neoplasm of urinary tract	0.895	0.105
R00.0 Tachycardia, unspecified	0.894	0.106
Chapter VI Diseases of the nervous system	0.893	0.107
N18.9 Chronic renal failure, unspecified	0.890	0.110
Z53.8 Procedure not carried out for other reasons	0.889	0.111
N18.0 End-stage renal disease	0.888	0.112
I21.9 Acute myocardial infarction, unspecified	0.888	0.112
K70-K77 Diseases of liver	0.887	0.113
I25.1 Atherosclerotic heart disease	0.886	0.114
E20-E35 Disorders of other endocrine glands	0.886	0.114
M25.46 Effusion of joint (Lower leg)	0.885	0.115
T82.1 Mechanical complication of cardiac electronic device	0.884	0.116
M25.53 Pain in joint (Forearm)	0.884	0.116
N70-N77 Inflammatory diseases of female pelvic organs	0.880	0.120
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.879	0.121
M79 Other soft tissue disorders, not elsewhere classified	0.879	0.121
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.877	0.123
E11 Non-insulin-dependent diabetes mellitus	0.876	0.124
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.876	0.124
A30-A49 Other bacterial diseases	0.875	0.125
Z57 Occupational exposure to risk-factors	0.873	0.127
M05-M14 Inflammatory polyarthropathies	0.872	0.128
I12 Hypertensive renal disease	0.870	0.130
Z50.1 Other physical therapy	0.869	0.131
I73 Other peripheral vascular diseases	0.869	0.131
C67.9 Bladder, unspecified	0.868	0.132
Z22.3 Carrier of other specified bacterial diseases	0.868	0.132
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.865	0.134
N32 Other disorders of bladder	0.864	0.136
K56 Paralytic ileus and intestinal obstruction without hernia	0.863	0.137
Q60-Q64 Congenital malformations of the urinary system	0.860	0.140
Z49 Care involving dialysis	0.860	0.140
K58 Irritable bowel syndrome	0.860	0.140
Z41 Procedures for purposes other than remedying health state	0.860	0.140
K08 Other disorders of teeth and supporting structures	0.858	0.142
N60-N64 Disorders of breast	0.856	0.144
N30 Cystitis	0.856	0.144
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.854	0.146
I30-I52 Other forms of heart disease	0.852	0.148
M47.9 Spondylosis, unspecified	0.850	0.150
W00-W19 Falls	0.850	0.150
G50-G59 Nerve, nerve root and plexus disorders	0.850	0.150
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.850	0.150
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.847	0.153
S20-S29 Injuries to the thorax	0.847	0.153
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.846	0.154
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.845	0.155
T90 Sequelae of injuries of head	0.845	0.155
S32 Fracture of lumbar spine and pelvis	0.845	0.155
A00-A09 Intestinal infectious diseases	0.844	0.156
Z42.1 Follow-up care involving plastic surgery of breast	0.842	0.158
I11 Hypertensive heart disease	0.842	0.158
H30-H36 Disorders of choroid and retina	0.840	0.160
M65 Synovitis and tenosynovitis	0.839	0.161
R02 Gangrene, not elsewhere classified	0.836	0.164
Z95 Presence of cardiac and vascular implants and grafts	0.835	0.165
N40-N51 Diseases of male genital organs	0.834	0.166
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.832	0.168
B95-B98 Bacterial, viral and other infectious agents	0.832	0.168
I22 Subsequent myocardial infarction	0.830	0.170
M47.8 Other spondylosis	0.830	0.170
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.830	0.170
M21 Other acquired deformities of limbs	0.829	0.171
Z87.8 Personal history of other specified conditions	0.828	0.172
K62 Other diseases of anus and rectum	0.827	0.173
R59 Enlarged lymph nodes	0.827	0.173
K50-K52 Noninfective enteritis and colitis	0.827	0.173
I73.9 Peripheral vascular disease, unspecified	0.826	0.174
M79.6 Pain in limb	0.825	0.175
M22 Disorders of patella	0.825	0.175
T82.3 Mechanical complication of other vascular grafts	0.824	0.176
E11.5 With peripheral circulatory complications	0.822	0.178
M40-M43 Deforming dorsopathies	0.822	0.178
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.820	0.180
Z94 Transplanted organ and tissue status	0.820	0.180
Z45.8 Adjustment and management of other implanted devices	0.819	0.181
Z96.7 Presence of other bone and tendon implants	0.818	0.182
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.818	0.182
Z45.2 Adjustment and management of vascular access device	0.815	0.185
Z89.5 Acquired absence of leg at or below knee	0.815	0.185
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.814	0.186
K70 Alcoholic liver disease	0.814	0.186
T93.8 Sequelae of other specified injuries of lower limb	0.813	0.187
Z83 Family history of other specific disorders	0.812	0.188
T51 Toxic effect of alcohol	0.811	0.188
G90-G99 Other disorders of the nervous system	0.810	0.189
R00.1 Bradycardia, unspecified	0.810	0.190
I20.8 Other forms of angina pectoris	0.810	0.190
Q80-Q89 Other congenital malformations	0.810	0.190
S00 Superficial injury of head	0.810	0.190
N80-N98 Noninflammatory disorders of female genital tract	0.809	0.191
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.809	0.191
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.807	0.193
Q61 Cystic kidney disease	0.806	0.194
K56.5 Intestinal adhesions [bands] with obstruction	0.806	0.194
C67.2 Lateral wall of bladder	0.804	0.196
I21.1 Acute transmural myocardial infarction of inferior wall	0.804	0.196
M25.0 Haemarthrosis	0.804	0.196
H55-H59 Other disorders of eye and adnexa	0.804	0.196
N25-N29 Other disorders of kidney and ureter	0.803	0.197
N32.0 Bladder-neck obstruction	0.803	0.197
K08.3 Retained dental root	0.802	0.198
K50 Crohn's disease [regional enteritis]	0.797	0.203
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.796	0.204
K58.9 Irritable bowel syndrome without diarrhoea	0.796	0.204
N00-N08 Glomerular diseases	0.796	0.204
Z88.3 Personal history of allergy to other anti-infective agents	0.795	0.205
Z52 Donors of organs and tissues	0.792	0.208
S06 Intracranial injury	0.792	0.208
Z00-Z13 Persons encountering health services for examination and investigation	0.792	0.208
M20 Acquired deformities of fingers and toes	0.791	0.209
K12 Stomatitis and related lesions	0.791	0.209
M80-M85 Disorders of bone density and structure	0.791	0.209
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.790	0.210
Y52 Agents primarily affecting the cardiovascular system	0.789	0.211
E22 Hyperfunction of pituitary gland	0.789	0.211
M35.3 Polymyalgia rheumatica	0.789	0.211
Z89.6 Acquired absence of leg above knee	0.789	0.211
N86 Erosion and ectropion of cervix uteri	0.788	0.212
T31 Burns classified according to extent of body surface involved	0.788	0.212
T87 Complications peculiar to reattachment and amputation	0.788	0.212
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.787	0.213
Z89.4 Acquired absence of foot and ankle	0.787	0.213
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.787	0.213
R80 Isolated proteinuria	0.787	0.213
I12.0 Hypertensive renal disease with renal failure	0.787	0.213
M13 Other arthritis	0.786	0.214
M47.1 Other spondylosis with myelopathy	0.786	0.214
N85 Other noninflammatory disorders of uterus, except cervix	0.786	0.214
X60-X84 Intentional self-harm	0.785	0.215
Z08 Follow-up examination after treatment for malignant neoplasm	0.784	0.216
I15 Secondary hypertension	0.783	0.217
R59.0 Localised enlarged lymph nodes	0.782	0.218
I77 Other disorders of arteries and arterioles	0.782	0.218
M25.6 Stiffness of joint, not elsewhere classified	0.781	0.219
E87 Other disorders of fluid, electrolyte and acid-base balance	0.781	0.219
M30 Polyarteritis nodosa and related conditions	0.780	0.220
I49 Other cardiac arrhythmias	0.779	0.221
T92 Sequelae of injuries of upper limb	0.779	0.221
M67 Other disorders of synovium and tendon	0.779	0.221
T39.1 4-Aminophenol derivatives	0.779	0.221
Chapter XII Diseases of the skin and subcutaneous tissue	0.779	0.221
Z49.0 Preparatory care for dialysis	0.778	0.222
H65-H75 Diseases of middle ear and mastoid	0.778	0.222
B35-B49 Mycoses	0.778	0.222
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.778	0.222
T79-T79 Certain early complications of trauma	0.777	0.222
N61 Inflammatory disorders of breast	0.777	0.223
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.777	0.223
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.777	0.223
M25.3 Other instability of joint	0.776	0.224
H33 Retinal detachments and breaks	0.775	0.225
K59 Other functional intestinal disorders	0.775	0.225
H04 Disorders of lachrymal system	0.774	0.226
K62.3 Rectal prolapse	0.774	0.226
M24 Other specific joint derangements	0.773	0.227
Chapter XXII Codes for special purposes	0.773	0.227
M79.8 Other specified soft tissue disorders	0.772	0.228
E78.2 Mixed hyperlipidaemia	0.772	0.228
T91 Sequelae of injuries of neck and trunk	0.771	0.229
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.771	0.229
E11.3 With ophthalmic complications	0.771	0.229
S80-S89 Injuries to the knee and lower leg	0.770	0.230
M65.9 Synovitis and tenosynovitis, unspecified	0.770	0.230
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.769	0.231
N73 Other female pelvic inflammatory diseases	0.769	0.231
F00-F09 Organic, including symptomatic, mental disorders	0.769	0.231
N30.9 Cystitis, unspecified	0.769	0.231
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.769	0.231
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.769	0.231
S09 Other and unspecified injuries of head	0.768	0.232
E50-E64 Other nutritional deficiencies	0.768	0.232
Z50.0 Cardiac rehabilitation	0.768	0.232
S32.0 Fracture of lumbar vertebra	0.768	0.232
I47 Paroxysmal tachycardia	0.765	0.235
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.764	0.236
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.764	0.236
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.762	0.238
A41 Other septicaemia	0.761	0.239
K62.5 Haemorrhage of anus and rectum	0.760	0.240
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.759	0.241
M25.50 Pain in joint (Multiple sites)	0.759	0.241
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.759	0.241
T20-T25 Burns and corrosions of external body surface, specified by site	0.759	0.241
H80-H83 Diseases of inner ear	0.758	0.242
Y51 Drugs primarily affecting the autonomic nervous system	0.758	0.242
N36 Other disorders of urethra	0.757	0.243
N18.4 Chronic kidney disease, stage 4	0.757	0.243
E78.9 Disorder of lipoprotein metabolism, unspecified	0.755	0.245
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.755	0.245
I24 Other acute ischaemic heart diseases	0.755	0.245
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.754	0.246
Z88.7 Personal history of allergy to serum and vaccine	0.753	0.247
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.752	0.248
V20-V29 Motorcycle rider injured in transport accident	0.752	0.248
M47.82 Other spondylosis (Cervical region)	0.752	0.248
S10-S19 Injuries to the neck	0.751	0.249
T39.0 Salicylates	0.751	0.249
M25.7 Osteophyte	0.751	0.249
R52 Pain, not elsewhere classified	0.751	0.249
M23.4 Loose body in knee	0.750	0.250
T78 Adverse effects, not elsewhere classified	0.750	0.250
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.749	0.251
M48 Other spondylopathies	0.749	0.251
Z83.7 Family history of diseases of the digestive system	0.749	0.251
M47.2 Other spondylosis with radiculopathy	0.748	0.252
K04 Diseases of pulp and periapical tissues	0.747	0.253
M79.65 Pain in limb (Pelvic region and thigh)	0.746	0.254
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.746	0.254
Z57.2 Occupational exposure to dust	0.746	0.254
E16 Other disorders of pancreatic internal secretion	0.746	0.254
N39 Other disorders of urinary system	0.746	0.254
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.746	0.254
T88 Other complications of surgical and medical care, not elsewhere classified	0.745	0.255
T75 Effects of other external causes	0.745	0.255
G57 Mononeuropathies of lower limb	0.744	0.256
Z57.3 Occupational exposure to other air contaminants	0.744	0.256
M25.8 Other specified joint disorders	0.744	0.256
M47.96 Spondylosis, unspecified (Lumbar region)	0.743	0.257
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.743	0.257
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.742	0.258
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.742	0.258
M17.3 Other posttraumatic gonarthrosis	0.741	0.259
I20.0 Unstable angina	0.741	0.259
M23.6 Other spontaneous disruption of ligament(s) of knee	0.740	0.259
Y57 Other and unspecified drugs and medicaments	0.740	0.260
M47.92 Spondylosis, unspecified (Cervical region)	0.740	0.260
A80-A89 Viral infections of the central nervous system	0.740	0.260
C60-C63 Malignant neoplasms of male genital organs	0.739	0.261
T68 Hypothermia	0.739	0.261
T50.9 Other and unspecified drugs, medicaments and biological substances	0.738	0.262
X40-X49 Accidental poisoning by and exposure to noxious substances	0.738	0.262
Z80 Family history of malignant neoplasm	0.738	0.262
N18.2 Chronic kidney disease, stage 2	0.737	0.263
Z95.0 Presence of cardiac pacemaker	0.737	0.263
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.737	0.263
T90.4 Sequelae of injury of eye and orbit	0.736	0.264
I05-I09 Chronic rheumatic heart diseases	0.735	0.265
Z94.0 Kidney transplant status	0.735	0.265
E78.0 Pure hypercholesterolaemia	0.734	0.266
Q61.3 Polycystic kidney, unspecified	0.734	0.266
K50.8 Other Crohn's disease	0.733	0.267
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.733	0.267
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.733	0.267
K11 Diseases of salivary glands	0.732	0.268
E13 Other specified diabetes mellitus	0.731	0.269
Q38-Q45 Other congenital malformations of the digestive system	0.731	0.269
C15-C26 Malignant neoplasms of digestive organs	0.730	0.270
E28 Ovarian dysfunction	0.730	0.270
E11.4 With neurological complications	0.730	0.270
I11.9 Hypertensive heart disease without (congestive) heart failure	0.729	0.271
M25.9 Joint disorder, unspecified	0.729	0.271
D00-D09 In situ neoplasms	0.729	0.271
R60 Oedema, not elsewhere classified	0.728	0.272
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.728	0.272
N85.2 Hypertrophy of uterus	0.728	0.272
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.728	0.272
F40-F48 Neurotic, stress-related and somatoform disorders	0.727	0.273
S00.8 Superficial injury of other parts of head	0.727	0.273
H10-H13 Disorders of conjunctiva	0.727	0.273
M13.9 Arthritis, unspecified	0.726	0.274
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.726	0.274
T31.0 Burns involving less than 10% of body surface	0.724	0.276
M35.0 Sicca syndrome [Sjogren]	0.724	0.276
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.723	0.277
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.723	0.277
I78 Diseases of capillaries	0.723	0.277
K02 Dental caries	0.723	0.277
M45 Ankylosing spondylitis	0.722	0.278
H36 Retinal disorders in diseases classified elsewhere	0.722	0.278
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.722	0.278
I77.1 Stricture of artery	0.721	0.279
M17.0 Primary gonarthrosis, bilateral	0.721	0.279
K50.9 Crohn's disease, unspecified	0.721	0.279
M46 Other inflammatory spondylopathies	0.720	0.280
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.720	0.280
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.720	0.280
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.720	0.280
R63.5 Abnormal weight gain	0.719	0.281
Z45.0 Adjustment and management of cardiac pacemaker	0.719	0.281
I46 Cardiac arrest	0.718	0.282
M79.9 Soft tissue disorder, unspecified	0.718	0.282
C67.4 Posterior wall of bladder	0.717	0.283
N20-N23 Urolithiasis	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z54 Convalescence	0.717	0.283
Z44 Fitting and adjustment of external prosthetic device	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
Z43 Attention to artificial openings	0.717	0.283
I13 Hypertensive heart and renal disease	0.717	0.283
H33.4 Traction detachment of retina	0.717	0.283
T81 Complications of procedures, not elsewhere classified	0.716	0.284
M25.2 Flail joint	0.716	0.284
M25.1 Fistula of joint	0.716	0.284
T80 Complications following infusion, transfusion and therapeutic injection	0.716	0.284
M10 Gout	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.715	0.285
M20.4 Other hammer toe(s) (acquired)	0.715	0.285
M31 Other necrotising vasculopathies	0.714	0.286
E65-E68 Obesity and other hyperalimentation	0.714	0.286
N40 Hyperplasia of prostate	0.714	0.286
M23.9 Internal derangement of knee, unspecified	0.714	0.286
M23.1 Discoid meniscus (congenital)	0.714	0.286
M23.0 Cystic meniscus	0.714	0.286
N37 Urethral disorders in diseases classified elsewhere	0.713	0.287
N34 Urethritis and urethral syndrome	0.713	0.287
N33 Bladder disorders in diseases classified elsewhere	0.713	0.287
M79.61 Pain in limb (Shoulder region)	0.713	0.287
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.713	0.287
I47.1 Supraventricular tachycardia	0.713	0.287
M25.54 Pain in joint (Hand)	0.713	0.287
S32.00 Fracture of lumbar vertebra (closed)	0.713	0.287
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.712	0.288
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.288
H60-H62 Diseases of external ear	0.712	0.288
Q82 Other congenital malformations of skin	0.712	0.288
R82 Other abnormal findings in urine	0.712	0.288
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.712	0.288
M91-M94 Chondropathies	0.711	0.289
I74 Arterial embolism and thrombosis	0.711	0.289
Z95.5 Presence of coronary angioplasty implant and graft	0.711	0.289
M00-M03 Infectious arthropathies	0.711	0.289
R07 Pain in throat and chest	0.710	0.290
Z87.6 Personal history of certain conditions arising in the perinatal period	0.710	0.290
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.710	0.290
T85.2 Mechanical complication of intraocular lens	0.710	0.290
M15 Polyarthrosis	0.709	0.291
S22 Fracture of rib(s), sternum and thoracic spine	0.708	0.292
Z82.3 Family history of stroke	0.707	0.292
M17.5 Other secondary gonarthrosis	0.707	0.293
M17.4 Other secondary gonarthrosis, bilateral	0.707	0.293
M17.2 Posttraumatic gonarthrosis, bilateral	0.707	0.293
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.707	0.293
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.707	0.293
T82.4 Mechanical complication of vascular dialysis catheter	0.707	0.293
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.707	0.293
T82.0 Mechanical complication of heart valve prosthesis	0.707	0.293
M25.59 Pain in joint (Site unspecified)	0.706	0.293
M25.58 Pain in joint (Other)	0.706	0.293
M25.52 Pain in joint (Upper arm)	0.706	0.293
C65 Malignant neoplasm of renal pelvis	0.706	0.293
G93 Other disorders of brain	0.706	0.294
K12.1 Other forms of stomatitis	0.706	0.294
N18.8 Other chronic renal failure	0.706	0.294
N18.1 Chronic kidney disease, stage 1	0.706	0.294
M86-M90 Other osteopathies	0.706	0.294
B99-B99 Other infectious diseases	0.706	0.294
B90-B94 Sequelae of infectious and parasitic diseases	0.706	0.294
B85-B89 Pediculosis, acariasis and other infestations	0.706	0.294
B65-B83 Helminthiases	0.706	0.294
B50-B64 Protozoal diseases	0.706	0.294
B20-B24 Human immunodeficiency virus [HIV] disease	0.706	0.294
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.706	0.294
A75-A79 Rickettsioses	0.706	0.294
A70-A74 Other diseases caused by chlamydiae	0.706	0.294
A65-A69 Other spirochaetal diseases	0.706	0.294
A20-A28 Certain zoonotic bacterial diseases	0.706	0.294
A15-A19 Tuberculosis	0.706	0.294
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.705	0.295
N30.2 Other chronic cystitis	0.705	0.295
Z95.1 Presence of aortocoronary bypass graft	0.705	0.295
T86 Failure and rejection of transplanted organs and tissues	0.705	0.295
M23.37 Other meniscus derangements-Capsular lig	0.705	0.295
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.705	0.295
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.705	0.295
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.705	0.295
N41 Inflammatory diseases of prostate	0.705	0.295
K75 Other inflammatory liver diseases	0.704	0.296
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.703	0.297
N35.8 Other urethral stricture	0.703	0.297
N35.1 Postinfective urethral stricture, not elsewhere classified	0.703	0.297
N35.0 Posttraumatic urethral stricture	0.703	0.297
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.702	0.297
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.702	0.297
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.702	0.297
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.702	0.297
Z82.2 Family history of deafness and hearing loss	0.702	0.297
Z82.1 Family history of blindness and visual loss	0.702	0.297

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations