TreeWAS – Variant ID: rs729761

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.152	0.848	0.000
E03 Other hypothyroidism	0.085	0.915	0.000
E03.8 Other specified hypothyroidism	0.072	0.928	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.064	0.936	0.000
E03.5 Myxoedema coma	0.061	0.939	0.000
E03.4 Atrophy of thyroid (acquired)	0.061	0.939	0.000
E03.3 Postinfectious hypothyroidism	0.061	0.939	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.061	0.939	0.000
N75.1 Abscess of Bartholin's gland	0.057	0.943	0.000
E03.1 Congenital hypothyroidism without goitre	0.056	0.944	0.000
N75 Diseases of Bartholin's gland	0.044	0.956	0.000
N23 Unspecified renal colic	0.000	0.958	0.042
N20.2 Calculus of kidney with calculus of ureter	0.000	0.960	0.040
N20 Calculus of kidney and ureter	0.000	0.961	0.039
N20-N23 Urolithiasis	0.000	0.962	0.038
N20.0 Calculus of kidney	0.000	0.963	0.037
N75.9 Disease of Bartholin's gland, unspecified	0.034	0.966	0.000
N75.8 Other diseases of Bartholin's gland	0.033	0.967	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.033	0.967	0.000
N70 Salpingitis and oophoritis	0.033	0.967	0.000
N76 Other inflammation of vagina and vulva	0.032	0.968	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.032	0.968	0.000
N76.0 Acute vaginitis	0.029	0.971	0.000
N76.4 Abscess of vulva	0.028	0.972	0.000
N76.8 Other specified inflammation of vagina and vulva	0.028	0.972	0.000
N75.0 Cyst of Bartholin's gland	0.027	0.972	0.000
N21 Calculus of lower urinary tract	0.000	0.973	0.027
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.973	0.027
N70.0 Acute salpingitis and oophoritis	0.027	0.973	0.000
N76.1 Subacute and chronic vaginitis	0.026	0.974	0.000
S22.20 Fracture of sternum (closed)	0.000	0.975	0.025
N76.5 Ulceration of vagina	0.025	0.975	0.000
N70.1 Chronic salpingitis and oophoritis	0.024	0.976	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.024	0.976	0.000
N21.1 Calculus in urethra	0.000	0.977	0.023
N21.8 Other lower urinary tract calculus	0.000	0.978	0.022
N76.6 Ulceration of vulva	0.022	0.978	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.022	0.978	0.000
N20.1 Calculus of ureter	0.000	0.979	0.021
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.979	0.020
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.980	0.020
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.980	0.020
N76.3 Subacute and chronic vulvitis	0.019	0.980	0.000
N71 Inflammatory disease of uterus, except cervix	0.019	0.980	0.000
N20.9 Urinary calculus, unspecified	0.000	0.981	0.019
N76.2 Acute vulvitis	0.018	0.982	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.017	0.983	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.017	0.983	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.017	0.983	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.017	0.983	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.017	0.983	0.000
N74.0 Tuberculous infection of cervix uteri	0.017	0.983	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.016	0.984	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
N73 Other female pelvic inflammatory diseases	0.015	0.985	0.000
N71.0 Acute inflammatory disease of uterus	0.014	0.986	0.000
S22.2 Fracture of sternum	0.000	0.986	0.014
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
N71.1 Chronic inflammatory disease of uterus	0.012	0.987	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.012	0.987	0.000
B34.9 Viral infection, unspecified	0.012	0.988	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.012	0.988	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.012	0.988	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.012	0.988	0.000
Z00.5 Examination of potential donor of organ and tissue	0.012	0.988	0.000
N73.4 Female chronic pelvic peritonitis	0.011	0.989	0.000
N73.3 Female acute pelvic peritonitis	0.011	0.989	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.011	0.989	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.011	0.989	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.011	0.989	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.011	0.989	0.000
I10 Essential (primary) hypertension	0.011	0.989	0.000
S22.21 Fracture of sternum (open)	0.000	0.990	0.010
Z00.4 General psychiatric examination, not elsewhere classified	0.010	0.990	0.000
N21.0 Calculus in bladder	0.000	0.990	0.010
N73.5 Female pelvic peritonitis, unspecified	0.010	0.990	0.000
D68 Other coagulation defects	0.009	0.991	0.000
D68.9 Coagulation defect, unspecified	0.009	0.991	0.000
D68.6 Other Thrombophilia	0.009	0.991	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.008	0.992	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.008	0.992	0.000
Z00.8 Other general examinations	0.008	0.992	0.000
D68.5 Primary Thrombophilia	0.008	0.992	0.000
Z00.3 Examination for adolescent development state	0.008	0.992	0.000
Z00.2 Examination for period of rapid growth in childhood	0.008	0.992	0.000
Z00.1 Routine child health examination	0.008	0.992	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.992	0.008
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Z00.0 General medical examination	0.007	0.993	0.000
D68.1 Hereditary factor XI deficiency	0.007	0.993	0.000
D68.4 Acquired coagulation factor deficiency	0.007	0.993	0.000
D68.0 Von Willebrand's disease	0.007	0.993	0.000
N72 Inflammatory disease of cervix uteri	0.006	0.994	0.000
D68.2 Hereditary deficiency of other clotting factors	0.006	0.994	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.994	0.006
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
N73.6 Female pelvic peritoneal adhesions	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
K83.8 Other specified diseases of biliary tract	0.006	0.994	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.005	0.994	0.000
K08 Other disorders of teeth and supporting structures	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
T17.2 Foreign body in pharynx	0.005	0.995	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.005	0.995	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.995	0.005
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.005	0.995	0.000
D69.9 Haemorrhagic condition, unspecified	0.005	0.995	0.000
K08.3 Retained dental root	0.005	0.995	0.000
B34 Viral infection of unspecified site	0.004	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.005	0.995	0.000
E80.4 Gilbert's syndrome	0.005	0.995	0.000
G82.2 Paraplegia, unspecified	0.005	0.995	0.000
K83.0 Cholangitis	0.005	0.995	0.000
Z99.1 Dependence on respirator	0.005	0.995	0.000
K83 Other diseases of biliary tract	0.004	0.996	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.996	0.004
S22.9 Fracture of bony thorax, part unspecified	0.000	0.996	0.004
S22.8 Fracture of other parts of bony thorax	0.000	0.996	0.004
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.996	0.004
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
D69.4 Other primary thrombocytopenia	0.004	0.996	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.004	0.996	0.000
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
Z03.1 Observation for suspected malignant neoplasm	0.000	0.996	0.004
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.996	0.004
S22.5 Flail chest	0.000	0.996	0.004
E00-E07 Disorders of thyroid gland	0.003	0.996	0.001
S22.3 Fracture of rib	0.000	0.996	0.004
K83.9 Disease of biliary tract, unspecified	0.004	0.996	0.000
M22.4 Chondromalacia patellae	0.004	0.996	0.000
B34.4 Papovirus infection, unspecified	0.004	0.996	0.000
K83.3 Fistula of bile duct	0.004	0.996	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
G82.1 Spastic paraplegia	0.004	0.996	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.004	0.996	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.996	0.004
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.996	0.000
B34.2 Coronavirus infection, unspecified	0.003	0.996	0.000
B34.0 Adenovirus infection, unspecified	0.003	0.996	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.996	0.004
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.996	0.000
D69.5 Secondary thrombocytopenia	0.003	0.996	0.000
B34.3 Parvovirus infection, unspecified	0.003	0.997	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.003
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.003
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.003
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.003
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
B34.1 Enterovirus infection, unspecified	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
K83.4 Spasm of sphincter of Oddi	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K83.2 Perforation of bile duct	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
K08.2 Atrophy of edentulous alveolar ridge	0.003	0.997	0.000
K83.5 Biliary cyst	0.003	0.997	0.000
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S22.51 Flail chest (open)	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.001
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.003
G80 Infantile cerebral palsy	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.997	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.003	0.997	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.997	0.003
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.003	0.997	0.000
G20 Parkinson's disease	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
E07 Other disorders of thyroid	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.003	0.997	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.003	0.997	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.997	0.003
S22.50 Flail chest (closed)	0.000	0.997	0.002
K26.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
K85 Acute pancreatitis	0.003	0.997	0.000
G80.1 Spastic diplegia	0.002	0.997	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.003	0.997	0.000
G80.2 Infantile hemiplegia	0.002	0.997	0.000
G82.4 Spastic tetraplegia	0.002	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.000	0.997	0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.997	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.997	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.997	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.997	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.997	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.997	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.997	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.997	0.001
E06 Thyroiditis	0.002	0.998	0.000
B34.8 Other viral infections of unspecified site	0.002	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.002	0.998	0.000
E04 Other non-toxic goitre	0.000	0.998	0.002
B35.3 Tinea pedis	0.002	0.998	0.000
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
G47.3 Sleep apnoea	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
G81 Hemiplegia	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
K85.8 Other acute pancreatitis	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
E87.7 Fluid overload	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
G81.1 Spastic hemiplegia	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
I42.8 Other cardiomyopathies	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
T17.5 Foreign body in bronchus	0.002	0.998	0.000
T17.3 Foreign body in larynx	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
K63.3 Ulcer of intestine	0.000	0.998	0.002
O97 Death from sequelae of direct obstetric causes	0.002	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.998	0.000
O95 Obstetric death of unspecified cause	0.002	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
E10.4 With neurological complications	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
K86 Other diseases of pancreas	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.000	0.998	0.002
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.998	0.002
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
F01 Vascular dementia	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
T17.4 Foreign body in trachea	0.002	0.998	0.000
T17.1 Foreign body in nostril	0.002	0.998	0.000
T17.0 Foreign body in nasal sinus	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.000	0.998	0.002
B24 Unspecified human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
G70-G73 Diseases of myoneural junction and muscle	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
E10.0 With coma	0.000	0.998	0.002
G81.0 Flaccid hemiplegia	0.002	0.998	0.000
G72 Other myopathies	0.002	0.998	0.000
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
I51.7 Cardiomegaly	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I11 Hypertensive heart disease	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.002	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
N03.9 Unspecified	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
G72.0 Drug-induced myopathy	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
G72.1 Alcoholic myopathy	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.998	0.001
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
F01.1 Multi-infarct dementia	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
G81.9 Hemiplegia, unspecified	0.002	0.998	0.000
M13.0 Polyarthritis, unspecified	0.000	0.998	0.002
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
R81 Glycosuria	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.998	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
G70.2 Congenital and developmental myasthenia	0.001	0.998	0.000
G70.1 Toxic myoneural disorders	0.001	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.001	0.998	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
G72.3 Periodic paralysis	0.001	0.998	0.000
G72.2 Myopathy due to other toxic agents	0.001	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.001	0.998	0.000
I15 Secondary hypertension	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
E10.7 With multiple complications	0.000	0.998	0.002
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.000	0.998	0.002
M13.06 Polyarthritis, unspecified (Lower leg)	0.000	0.998	0.001
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
E80.1 Porphyria cutanea tarda	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.001	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.001	0.998	0.000
G23.2 Striatonigral degeneration	0.001	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.001	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.001	0.998	0.000
Z29 Need for other prophylactic measures	0.000	0.998	0.002
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.002	0.998	0.000
G21.4 Vascular parkinsonism	0.001	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.001	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.001	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
R50.8 Other specified fever	0.000	0.998	0.002
M13.04 Polyarthritis, unspecified (Hand)	0.000	0.998	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.998	0.001
E05.5 Thyroid crisis or storm	0.001	0.998	0.001
E05.4 Thyrotoxicosis factitia	0.001	0.998	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.998	0.001
G21.9 Secondary Parkinsonism, unspecified	0.001	0.998	0.000
G25.5 Other chorea	0.001	0.998	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
M13.08 Polyarthritis, unspecified (Other)	0.000	0.998	0.001
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.000	0.998	0.001
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M13.03 Polyarthritis, unspecified (Forearm)	0.000	0.998	0.001
M13.02 Polyarthritis, unspecified (Upper arm)	0.000	0.998	0.001
M13.01 Polyarthritis, unspecified (Shoulder region)	0.000	0.998	0.001
G21.8 Other secondary Parkinsonism	0.001	0.998	0.000
G21.3 Postencephalitic Parkinsonism	0.001	0.998	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.001	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.001	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.001	0.998	0.000
G25.2 Other specified forms of tremor	0.001	0.998	0.000
G25.1 Drug-induced tremor	0.001	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.001	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.001
S93.1 Dislocation of toe(s)	0.000	0.998	0.001
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.998	0.001
G11.4 Hereditary spastic paraplegia	0.001	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
G11 Hereditary ataxia	0.001	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.998	0.001
E80.6 Other disorders of bilirubin metabolism	0.001	0.998	0.000
G72.8 Other specified myopathies	0.001	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.001	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.001	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.001
G25.3 Myoclonus	0.001	0.999	0.000
G73.7 Myopathy other diseases classified elsewhere	0.001	0.999	0.000
G73.6 Myopathy in metabolic diseases	0.001	0.999	0.000
G73.5 Myopathy in endocrine diseases	0.001	0.999	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.001	0.999	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.001	0.999	0.000
G73.1 Eaton-Lambert syndrome	0.001	0.999	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.001	0.999	0.000
S23.4 Sprain and strain of ribs and sternum	0.000	0.999	0.001
F02 Dementia in other diseases classified elsewhere	0.001	0.999	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
E10.6 With other specified complications	0.000	0.999	0.001
I15.9 Seconday hypertension, unspecified	0.001	0.999	0.000
M94.8 Other specified disorders of cartilage	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.999	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.999	0.001
D09.0 Bladder	0.000	0.999	0.001
E04.2 Non-toxic multinodular goitre	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.001	0.999	0.000
H33.4 Traction detachment of retina	0.001	0.999	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.001	0.999	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.999	0.001
S26 Injury of heart	0.000	0.999	0.001
S25 Injury of blood vessels of thorax	0.000	0.999	0.001
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
E05.8 Other thyrotoxicosis	0.001	0.999	0.001
F02.3 Dementia in Parkinson's disease	0.001	0.999	0.000
F05.8 Other delirium	0.001	0.999	0.000
F05.1 Delirium superimposed on dementia	0.001	0.999	0.000
I15.8 Other secondary hypertension	0.001	0.999	0.000
I15.0 Renovascular hypertension	0.001	0.999	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.999	0.000
F02.0 Dementia in Pick's disease	0.001	0.999	0.000
K72.1 Chronic hepatic failure	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.001	0.999	0.000
N80.1 Endometriosis of ovary	0.001	0.999	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.999	0.001
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.001	0.999	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.000	0.999	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.999	0.001
S24 Injury of nerves and spinal cord at thorax level	0.000	0.999	0.001
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.999	0.001
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.999	0.001
S23.3 Sprain and strain of thoracic spine	0.000	0.999	0.001
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.999	0.001
S23.1 Dislocation of thoracic vertebra	0.000	0.999	0.001
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.999	0.001
S27.1 Traumatic haemothorax	0.001	0.999	0.001
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.999	0.001
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations