TreeWAS – Variant ID: rs72986571

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
F10 Mental and behavioural disorders due to use of alcohol	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.999	0.001
Chapter VI Diseases of the nervous system	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.997	0.003
F10.0 Acute intoxication	0.994	0.006
F10.3 Withdrawal state	0.992	0.008
Chapter XIV Diseases of the genitourinary system	0.989	0.011
S00-S09 Injuries to the head	0.988	0.012
N40-N51 Diseases of male genital organs	0.987	0.013
N47 Redundant prepuce, phimosis and paraphimosis	0.986	0.014
G00-G09 Inflammatory diseases of the central nervous system	0.985	0.015
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.972	0.028
S00 Superficial injury of head	0.969	0.031
T36-T50 Poisoning by drugs, medicaments and biological substances	0.967	0.033
S00.8 Superficial injury of other parts of head	0.964	0.036
B95-B98 Bacterial, viral and other infectious agents	0.961	0.039
G80-G83 Cerebral palsy and other paralytic syndromes	0.956	0.044
Chapter VIII Diseases of the ear and mastoid process	0.949	0.051
G90-G99 Other disorders of the nervous system	0.931	0.069
F10.1 Harmful use	0.929	0.071
F10.2 Dependence syndrome	0.923	0.077
N10-N16 Renal tubulo-interstitial diseases	0.921	0.079
S40-S49 Injuries to the shoulder and upper arm	0.919	0.081
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.919	0.081
G04 Encephalitis, myelitis and encephalomyelitis	0.915	0.085
A30-A49 Other bacterial diseases	0.915	0.085
N40 Hyperplasia of prostate	0.912	0.088
G82 Paraplegia and tetraplegia	0.911	0.089
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.909	0.091
N00-N08 Glomerular diseases	0.905	0.095
B35-B49 Mycoses	0.903	0.097
H60-H62 Diseases of external ear	0.898	0.102
N13 Obstructive and reflux uropathy	0.889	0.111
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.886	0.114
N25-N29 Other disorders of kidney and ureter	0.885	0.115
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.879	0.121
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.871	0.129
S32 Fracture of lumbar spine and pelvis	0.870	0.130
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.865	0.135
S03 Dislocation, sprain and strain of joints and ligaments of head	0.860	0.140
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.859	0.141
B25-B34 Other viral diseases	0.856	0.144
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.849	0.151
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.849	0.151
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.844	0.156
T40.2 Other opioids	0.841	0.159
G91 Hydrocephalus	0.837	0.163
S02 Fracture of skull and facial bones	0.834	0.166
G06 Intracranial and intraspinal abscess and granuloma	0.834	0.166
G09 Sequelae of inflammatory diseases of central nervous system	0.829	0.171
G70-G73 Diseases of myoneural junction and muscle	0.829	0.171
T20-T25 Burns and corrosions of external body surface, specified by site	0.825	0.175
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.825	0.175
S90-S99 Injuries to the ankle and foot	0.823	0.177
G81 Hemiplegia	0.823	0.177
Chapter XXII Codes for special purposes	0.820	0.180
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.819	0.181
G82.2 Paraplegia, unspecified	0.818	0.182
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.817	0.183
G95 Other diseases of spinal cord	0.816	0.184
H60 Otitis externa	0.815	0.185
N13.5 Kinking and stricture of ureter without hydronephrosis	0.808	0.192
S50-S59 Injuries to the elbow and forearm	0.807	0.193
F10.5 Psychotic disorder	0.803	0.197
B37 Candidiasis	0.802	0.198
N43 Hydrocele and spermatocele	0.802	0.198
A80-A89 Viral infections of the central nervous system	0.799	0.201
G03 Meningitis due to other and unspecified causes	0.798	0.201
F99-F99 Unspecified mental disorder	0.795	0.205
A49 Bacterial infection of unspecified site	0.795	0.205
N26 Unspecified contracted kidney	0.794	0.206
T42.4 Benzodiazepines	0.792	0.208
G40-G47 Episodic and paroxysmal disorders	0.792	0.208
S41 Open wound of shoulder and upper arm	0.791	0.209
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.790	0.210
S60-S69 Injuries to the wrist and hand	0.790	0.210
N05 Unspecified nephritic syndrome	0.789	0.211
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.788	0.212
H61 Other disorders of external ear	0.787	0.213
A15-A19 Tuberculosis	0.785	0.215
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.784	0.216
B90-B94 Sequelae of infectious and parasitic diseases	0.783	0.217
S00.0 Superficial injury of scalp	0.781	0.219
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.780	0.220
H60.9 Otitis externa, unspecified	0.779	0.221
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.778	0.222
G96 Other disorders of central nervous system	0.776	0.224
S10-S19 Injuries to the neck	0.775	0.225
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.774	0.226
G82.5 Tetraplegia, unspecified	0.772	0.228
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.771	0.229
S03.2 Dislocation of tooth	0.769	0.231
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.767	0.233
F12 Mental and behavioural disorders due to use of cannabinoids	0.767	0.233
T80 Complications following infusion, transfusion and therapeutic injection	0.767	0.233
S06 Intracranial injury	0.766	0.234
S43.0 Dislocation of shoulder joint	0.763	0.237
S30 Superficial injury of abdomen, lower back and pelvis	0.763	0.237
F80-F89 Disorders of psychological development	0.760	0.240
H90-H95 Other disorders of ear	0.759	0.241
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.758	0.242
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.755	0.245
G82.4 Spastic tetraplegia	0.754	0.246
T87 Complications peculiar to reattachment and amputation	0.754	0.246
T84.1 Mechanical complication of internal fixation device of bones of limb	0.753	0.247
S02.1 Fracture of base of skull	0.753	0.247
A65-A69 Other spirochaetal diseases	0.752	0.247
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.752	0.248
N13.8 Other obstructive and reflux uropathy	0.749	0.251
T84.2 Mechanical complication of internal fixation device of other bones	0.748	0.252
A41 Other septicaemia	0.745	0.254
B34 Viral infection of unspecified site	0.745	0.255
S31 Open wound of abdomen, lower back and pelvis	0.745	0.255
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.743	0.257
B49 Unspecified mycosis	0.742	0.258
G35-G37 Demyelinating diseases of the central nervous system	0.742	0.258
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.742	0.258
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.741	0.259
G91.9 Hydrocephalus, unspecified	0.741	0.259
G30-G32 Other degenerative diseases of the nervous system	0.741	0.259
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.741	0.259
N25 Disorders resulting from impaired renal tubular function	0.735	0.265
N02 Recurrent and persistent haematuria	0.733	0.266
F10.9 Unspecified mental and behavioural disorder	0.732	0.268
G20-G26 Extrapyramidal and movement disorders	0.730	0.270
N13.9 Obstructive and reflux uropathy, unspecified	0.729	0.271
N11 Chronic tubulo-interstitial nephritis	0.728	0.272
B99-B99 Other infectious diseases	0.728	0.272
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.726	0.274
T92 Sequelae of injuries of upper limb	0.724	0.276
N17-N19 Renal failure	0.724	0.276
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.722	0.278
H65-H75 Diseases of middle ear and mastoid	0.722	0.278
S01 Open wound of head	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F10.8 Other mental and behavioural disorders	0.717	0.283
F10.7 Residual and late-onset psychotic disorder	0.717	0.283
F10.6 Amnesic syndrome	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.717	0.283
F18 Mental and behavioural disorders due to use of volatile solvents	0.717	0.283
F16 Mental and behavioural disorders due to use of hallucinogens	0.717	0.283
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.717	0.283
F14 Mental and behavioural disorders due to use of cocaine	0.717	0.283
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.717	0.283
F11 Mental and behavioural disorders due to use of opioids	0.717	0.283
S37 Injury of urinary and pelvic organs	0.715	0.285
G41 Status epilepticus	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.715	0.285
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285
B50-B64 Protozoal diseases	0.715	0.285
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285
A75-A79 Rickettsioses	0.715	0.285
A70-A74 Other diseases caused by chlamydiae	0.715	0.285
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.288
N46 Male infertility	0.711	0.289
S00.7 Multiple superficial injuries of head	0.711	0.289
F30-F39 Mood [affective] disorders	0.710	0.290
S52 Fracture of forearm	0.709	0.291
S08 Traumatic amputation of part of head	0.708	0.291
S07 Crushing injury of head	0.708	0.291
S04 Injury of cranial nerves	0.708	0.291
N51 Disorders of male genital organs in diseases classified elsewhere	0.707	0.292
N44 Torsion of testis	0.707	0.292
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.706	0.293
G00 Bacterial meningitis, not elsewhere classified	0.706	0.293
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.706	0.293
G01 Meningitis in bacterial diseases classified elsewhere	0.706	0.293
T15-T19 Effects of foreign body entering through natural orifice	0.706	0.294
S20-S29 Injuries to the thorax	0.705	0.295
B65-B83 Helminthiases	0.704	0.296
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.703	0.297
N50 Other disorders of male genital organs	0.702	0.298
S32.1 Fracture of sacrum	0.702	0.298
B37.3 Candidiasis of vulva and vagina	0.702	0.298
S41.1 Open wound of upper arm	0.700	0.300
G81.1 Spastic hemiplegia	0.699	0.301
A41.5 Septicaemia due to other Gram-negative organisms	0.698	0.302
A48 Other bacterial diseases, not elsewhere classified	0.698	0.302
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.697	0.303
S36 Injury of intra-abdominal organs	0.697	0.303
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.697	0.303
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.697	0.303
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.697	0.303
A49.9 Bacterial infection, unspecified	0.695	0.305
N03 Chronic nephritic syndrome	0.695	0.305
S02.10 Fracture of base of skull (closed)	0.695	0.305
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.695	0.305
S00.4 Superficial injury of ear	0.694	0.305
F10.4 Withdrawal state with delirium	0.694	0.306
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.693	0.307
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.693	0.307
T41 Poisoning by anaesthetics and therapeutic gases	0.693	0.307
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.693	0.307
T36 Poisoning by systemic antibiotics	0.693	0.307
G45 Transient cerebral ischaemic attacks and related syndromes	0.692	0.308
S32.4 Fracture of acetabulum	0.691	0.309
S00.5 Superficial injury of lip and oral cavity	0.690	0.310
T87.6 Other and unspecified complications of amputation stump	0.689	0.311
F60-F69 Disorders of adult personality and behaviour	0.687	0.313
G80 Infantile cerebral palsy	0.687	0.313
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.686	0.314
S49 Other and unspecified injuries of shoulder and upper arm	0.685	0.315
A40 Streptococcal septicaemia	0.685	0.315
N18 Chronic renal failure	0.684	0.316
S64 Injury of nerves at wrist and hand level	0.684	0.316
N27 Small kidney of unknown cause	0.683	0.317
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.681	0.319
T42.1 Iminostilbenes	0.680	0.319
G06.1 Intraspinal abscess and granuloma	0.678	0.322
N08 Glomerular disorders in diseases classified elsewhere	0.678	0.322
T46 Poisoning by agents primarily affecting the cardiovascular system	0.678	0.322
N13.6 Pyonephrosis	0.678	0.322
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.675	0.324
H61.0 Perichondritis of external ear	0.675	0.325
S32.3 Fracture of ilium	0.674	0.326
S32.0 Fracture of lumbar vertebra	0.673	0.327
T66-T78 Other and unspecified effects of external causes	0.673	0.327
T92.1 Sequelae of fracture of arm	0.673	0.327
N13.4 Hydroureter	0.672	0.328
S90 Superficial injury of ankle and foot	0.671	0.329
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.670	0.330
G72 Other myopathies	0.670	0.330
N43.3 Hydrocele, unspecified	0.669	0.331
G91.1 Obstructive hydrocephalus	0.669	0.331
G06.2 Extradural and subdural abscess, unspecified	0.668	0.332
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.668	0.332
G94 Other disorders of brain in diseases classified elsewhere	0.668	0.332
G98 Other disorders of nervous system, not elsewhere classified	0.668	0.332
G92 Toxic encephalopathy	0.668	0.332
F50 Eating disorders	0.667	0.332
S60 Superficial injury of wrist and hand	0.666	0.334
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.665	0.335
G90 Disorders of autonomic nervous system	0.665	0.335
G03.9 Meningitis, unspecified	0.664	0.335
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.664	0.336
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.664	0.336
S32.7 Multiple fractures of lumbar spine and pelvis	0.663	0.337
N48 Other disorders of penis	0.663	0.337
G95.1 Vascular myelopathies	0.661	0.339
S46 Injury of muscle and tendon at shoulder and upper arm level	0.661	0.339
N99-N99 Other disorders of the genitourinary system	0.661	0.339
G41.9 Status epilepticus, unspecified	0.661	0.339
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.660	0.340
N15 Other renal tubulo-interstitial diseases	0.660	0.340
N60-N64 Disorders of breast	0.660	0.340
F00-F09 Organic, including symptomatic, mental disorders	0.659	0.341
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.659	0.341
S48 Traumatic amputation of shoulder and upper arm	0.659	0.341
S45 Injury of blood vessels at shoulder and upper arm level	0.659	0.341
S44 Injury of nerves at shoulder and upper arm level	0.659	0.341
S47 Crushing injury of shoulder and upper arm	0.659	0.341
T38.1 Thyroid hormones and substitutes	0.658	0.341
T23 Burn and corrosion of wrist and hand	0.658	0.342
S01.0 Open wound of scalp	0.658	0.342
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.656	0.344
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.656	0.344
G04.1 Tropical spastic paraplegia	0.656	0.344
G04.0 Acute disseminated encephalitis	0.656	0.344
A44 Bartonellosis	0.656	0.344
A43 Nocardiosis	0.656	0.344
A42 Actinomycosis	0.656	0.344
A39 Meningococcal infection	0.656	0.344
A37 Whooping cough	0.656	0.344
A36 Diphtheria	0.656	0.344
A32 Listeriosis	0.656	0.344
A31 Infection due to other mycobacteria	0.656	0.344
A30 Leprosy [Hansen's disease]	0.656	0.344
A38 Scarlet fever	0.656	0.344
A35 Other tetanus	0.656	0.344
A34 Obstetrical tetanus	0.656	0.344
A33 Tetanus neonatorum	0.656	0.344
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.655	0.345
B34.9 Viral infection, unspecified	0.655	0.345
G82.3 Flaccid tetraplegia	0.653	0.347
G82.0 Flaccid paraplegia	0.653	0.347
N05.9 Unspecified	0.652	0.348
A46 Erysipelas	0.652	0.348
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.652	0.348
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.652	0.348
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.650	0.350
N07 Hereditary nephropathy, not elsewhere classified	0.649	0.351
N06 Isolated proteinuria with specified morphological lesion	0.649	0.351
N01 Rapidly progressive nephritic syndrome	0.649	0.351
N00 Acute nephritic syndrome	0.649	0.351
G70 Myasthenia gravis and other myoneural disorders	0.649	0.351
F99 Mental disorder, not otherwise specified	0.648	0.352
S92 Fracture of foot, except ankle	0.648	0.352
B48 Other mycoses, not elsewhere classified	0.647	0.353
B47 Mycetoma	0.647	0.353
B46 Zygomycosis	0.647	0.353
B45 Cryptococcosis	0.647	0.353
B43 Chromomycosis and phaeomycotic abscess	0.647	0.353
B42 Sporotrichosis	0.647	0.353
B41 Paracoccidioidomycosis	0.647	0.353
B40 Blastomycosis	0.647	0.353
B39 Histoplasmosis	0.647	0.353
B38 Coccidioidomycosis	0.647	0.353
B36 Other superficial mycoses	0.647	0.353
B15-B19 Viral hepatitis	0.647	0.353
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.646	0.353
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.645	0.354
G95.9 Disease of spinal cord, unspecified	0.644	0.356
H62 Disorders of external ear in diseases classified elsewhere	0.644	0.356
G81.9 Hemiplegia, unspecified	0.643	0.357
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.643	0.357
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.642	0.358
B44 Aspergillosis	0.640	0.360
G82.1 Spastic paraplegia	0.638	0.362
T91 Sequelae of injuries of neck and trunk	0.638	0.362
G95.2 Cord compression, unspecified	0.638	0.362
N13.7 Vesicoureteral-reflux-associated uropathy	0.637	0.362
A49.8 Other bacterial infections of unspecified site	0.637	0.363
S02.2 Fracture of nasal bones	0.637	0.363
T88 Other complications of surgical and medical care, not elsewhere classified	0.637	0.363
T79-T79 Certain early complications of trauma	0.636	0.364
B25 Cytomegaloviral disease	0.636	0.364
B35 Dermatophytosis	0.636	0.364
G40 Epilepsy	0.636	0.364
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.636	0.364
T40.8 Lysergide [LSD]	0.636	0.364
T40.7 Cannabis (derivatives)	0.636	0.364
T40.5 Cocaine	0.636	0.364
T40.3 Methadone	0.636	0.364
T40.1 Heroin	0.636	0.364
T40.0 Opium	0.636	0.364
T39.1 4-Aminophenol derivatives	0.635	0.365
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.634	0.366
N04 Nephrotic syndrome	0.634	0.366
B20-B24 Human immunodeficiency virus [HIV] disease	0.634	0.366
S40 Superficial injury of shoulder and upper arm	0.633	0.366
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.633	0.367
B37.1 Pulmonary candidiasis	0.632	0.367
B37.9 Candidiasis, unspecified	0.631	0.369
G96.8 Other specified disorders of central nervous system	0.631	0.369
B00 Herpesviral [herpes simplex] infections	0.630	0.369
S64.4 Injury of digital nerve of other finger	0.630	0.370
T86 Failure and rejection of transplanted organs and tissues	0.630	0.370
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.630	0.370
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.630	0.370
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.630	0.370
B91 Sequelae of poliomyelitis	0.629	0.371
S06.6 Traumatic subarachnoid haemorrhage	0.628	0.372
T80.2 Infections following infusion, transfusion and therapeutic injection	0.628	0.372
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.628	0.372
N25.8 Other disorders resulting from impaired renal tubular function	0.628	0.372
A86 Unspecified viral encephalitis	0.627	0.372
H80-H83 Diseases of inner ear	0.627	0.373
S91 Open wound of ankle and foot	0.626	0.374
N18.5 Chronic kidney disease, stage 5	0.626	0.374
S01.4 Open wound of cheek and temporomandibular area	0.625	0.374
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.625	0.375
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.625	0.375
T42.5 Mixed antiepileptics, not elsewhere classified	0.625	0.375
T42.3 Barbiturates	0.625	0.375
T42.2 Succinimides and oxazolidinediones	0.625	0.375
T42.0 Hydantoin derivatives	0.625	0.375
A49.0 Staphylococcal infection, unspecified	0.624	0.376
S32.2 Fracture of coccyx	0.624	0.376
S30.1 Contusion of abdominal wall	0.623	0.377
G93 Other disorders of brain	0.623	0.377
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.622	0.377
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.621	0.378
S02.9 Fracture of skull and facial bones, part unspecified	0.620	0.380
N50.8 Other specified disorders of male genital organs	0.620	0.380
N64 Other disorders of breast	0.619	0.381
N18.2 Chronic kidney disease, stage 2	0.619	0.381
S60.2 Contusion of other parts of wrist and hand	0.619	0.381
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.617	0.383
S32.5 Fracture of pubis	0.617	0.383
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.617	0.383
S03.4 Sprain and strain of jaw	0.617	0.383
S03.3 Dislocation of other and unspecified parts of head	0.617	0.383
S03.1 Dislocation of septal cartilage of nose	0.617	0.383
S03.0 Dislocation of jaw	0.617	0.383
T40.6 Other and unspecified narcotics	0.616	0.383
S02.5 Fracture of tooth	0.616	0.384
H61.2 Impacted cerumen	0.615	0.385
S00.2 Other superficial injuries of eyelid and periocular area	0.614	0.385
Q50-Q56 Congenital malformations of genital organs	0.614	0.386
B33 Other viral diseases, not elsewhere classified	0.614	0.386
B30 Viral conjunctivitis	0.614	0.386
B27 Infectious mononucleosis	0.614	0.386
B26 Mumps	0.614	0.386
G96.0 Cerebrospinal fluid leak	0.613	0.387
T98 Sequelae of other and unspecified effects of external causes	0.612	0.387
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.612	0.388
A87 Viral meningitis	0.612	0.388
N45 Orchitis and epididymitis	0.612	0.388
Q38-Q45 Other congenital malformations of the digestive system	0.610	0.390
S42 Fracture of shoulder and upper arm	0.609	0.391
S52.6 Fracture of lower end of both ulna and radius	0.609	0.391
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.608	0.392
S65 Injury of blood vessels at wrist and hand level	0.608	0.392
A41.0 Septicaemia due to Staphylococcus aureus	0.608	0.392
S54 Injury of nerves at forearm level	0.606	0.394
S69 Other and unspecified injuries of wrist and hand	0.606	0.394
G37 Other demyelinating diseases of central nervous system	0.605	0.395
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.602	0.398
G95.8 Other specified diseases of spinal cord	0.601	0.399
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.601	0.399
S00.1 Contusion of eyelid and periocular area	0.601	0.399
F12.1 Harmful use	0.601	0.399
G91.8 Other hydrocephalus	0.600	0.400
G91.3 Posttraumatic hydrocephalus, unspecified	0.600	0.400
G91.2 Normal-pressure hydrocephalus	0.600	0.400
G91.0 Communicating hydrocephalus	0.600	0.400
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.599	0.401
S02.3 Fracture of orbital floor	0.599	0.401
S02.7 Multiple fractures involving skull and facial bones	0.598	0.402
G06.0 Intracranial abscess and granuloma	0.598	0.402
H61.3 Acquired stenosis of external ear canal	0.596	0.404
S00.3 Superficial injury of nose	0.595	0.405
S12 Fracture of neck	0.595	0.405
T09 Other injuries of spine and trunk, level unspecified	0.594	0.405
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.594	0.406
G71 Primary disorders of muscles	0.594	0.406
S66 Injury of muscle and tendon at wrist and hand level	0.594	0.406
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.594	0.406
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.593	0.406
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.593	0.407
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.592	0.407
N18.4 Chronic kidney disease, stage 4	0.592	0.408
T25 Burn and corrosion of ankle and foot	0.591	0.408
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.591	0.408
T21 Burn and corrosion of trunk	0.591	0.408
T20 Burn and corrosion of head and neck	0.591	0.408
U89 Agent resistant to other and unspecified antibiotics	0.591	0.409
F31 Bipolar affective disorder	0.591	0.409
T95 Sequelae of burns, corrosions and frostbite	0.591	0.409
T94 Sequelae of injuries involving multiple and unspecified body regions	0.591	0.409
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.591	0.409
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.591	0.409
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.591	0.409
S98 Traumatic amputation of ankle and foot	0.590	0.410
S97 Crushing injury of ankle and foot	0.590	0.410
S96 Injury of muscle and tendon at ankle and foot level	0.590	0.410
S95 Injury of blood vessels at ankle and foot level	0.590	0.410
S94 Injury of nerves at ankle and foot level	0.590	0.410
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.590	0.410
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.590	0.410
G81.0 Flaccid hemiplegia	0.590	0.410
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.590	0.410
H66 Suppurative and unspecified otitis media	0.590	0.410
G24 Dystonia	0.589	0.411
N48.1 Balanoposthitis	0.589	0.411
S06.9 Intracranial injury, unspecified	0.589	0.411
T40.4 Other synthetic narcotics	0.588	0.412
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.587	0.413
T38.9 Other and unspecified hormone antagonists	0.587	0.413
T38.8 Other and unspecified hormones and their synthetic substitutes	0.587	0.413
T38.7 Androgens and anabolic congeners	0.587	0.413
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.587	0.413
T38.5 Other oestrogens and progestogens	0.587	0.413
T38.4 Oral contraceptives	0.587	0.413
T38.2 Antithyroid drugs	0.587	0.413
T38.0 Glucocorticoids and synthetic analogues	0.587	0.413
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.587	0.413
G95.0 Syringomyelia and syringobulbia	0.587	0.413
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.587	0.413
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.586	0.414
S43.6 Sprain and strain of sternoclavicular joint	0.586	0.414
S43.5 Sprain and strain of acromioclavicular joint	0.586	0.414
S43.4 Sprain and strain of shoulder joint	0.586	0.414
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.586	0.414
S43.2 Dislocation of sternoclavicular joint	0.586	0.414
H60.8 Other otitis externa	0.584	0.416
H60.5 Acute otitis externa, non-infective	0.584	0.416
H60.4 Cholesteatoma of external ear	0.584	0.416
H60.3 Other infective otitis externa	0.584	0.416
H60.2 Malignant otitis externa	0.584	0.416
H60.0 Abscess of external ear	0.584	0.416
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.584	0.416
S31.8 Open wound of other and unspecified parts of abdomen	0.583	0.417
N05.2 Diffuse membranous glomerulonephritis	0.582	0.418
S32.10 Fracture of sacrum (closed)	0.581	0.419
S06.2 Diffuse brain injury	0.581	0.419
A41.2 Septicaemia due to unspecified staphylococcus	0.581	0.419
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.580	0.420
S52.4 Fracture of shafts of both ulna and radius	0.580	0.420
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.579	0.421
G20 Parkinson's disease	0.579	0.421
S59 Other and unspecified injuries of forearm	0.578	0.421
S58 Traumatic amputation of forearm	0.578	0.421
S57 Crushing injury of forearm	0.578	0.421
S56 Injury of muscle and tendon at forearm level	0.578	0.421
S55 Injury of blood vessels at forearm level	0.578	0.421
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.578	0.421
H91 Other hearing loss	0.578	0.422
G83 Other paralytic syndromes	0.577	0.422
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.577	0.423
A69 Other spirochaetal infections	0.577	0.423

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations