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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72991078
log Bayes Factor = 15.803
Chromosome 2   position 238,732,864  (GRCh37) Explore rs72991078 on Ensembl!
Variant rs72991078 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.990 0.010 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.986 0.014 0.000
G90-G99 Other disorders of the nervous system
0.984 0.016 0.000
T43.2 Other and unspecified antidepressants
0.983 0.017 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.979 0.021 0.000
F30-F39 Mood [affective] disorders
0.976 0.024 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.974 0.026 0.000
S60-S69 Injuries to the wrist and hand
0.974 0.026 0.000
C25 Malignant neoplasm of pancreas
0.970 0.030 0.000
T39.1 4-Aminophenol derivatives
0.969 0.031 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.964 0.036 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
R06 Abnormalities of breathing
0.959 0.041 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.958 0.042 0.000
Chapter IX Diseases of the circulatory system
0.957 0.043 0.000
M20-M25 Other joint disorders
0.954 0.046 0.000
S62 Fracture at wrist and hand level
0.946 0.054 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
Chapter XXI Factors influencing health status and contact with health services
0.946 0.054 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
M47 Spondylosis
0.943 0.057 0.000
M25 Other joint disorders, not elsewhere classified
0.941 0.059 0.000
Chapter VIII Diseases of the ear and mastoid process
0.940 0.060 0.000
R00 Abnormalities of heart beat
0.939 0.061 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.938 0.062 0.000
D10-D36 Benign neoplasms
0.938 0.062 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.937 0.063 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
R00.0 Tachycardia, unspecified
0.932 0.068 0.000
I60-I69 Cerebrovascular diseases
0.930 0.070 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.930 0.070 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.927 0.073 0.000
Chapter XXII Codes for special purposes
0.927 0.073 0.000
M65-M68 Disorders of synovium and tendon
0.926 0.074 0.000
Z45 Adjustment and management of implanted device
0.923 0.077 0.000
F32 Depressive episode
0.922 0.078 0.000
G56 Mononeuropathies of upper limb
0.918 0.082 0.000
M47.8 Other spondylosis
0.914 0.086 0.000
C20 Malignant neoplasm of rectum
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
Chapter VII Diseases of the eye and adnexa
0.911 0.089 0.000
M25.5 Pain in joint
0.911 0.089 0.000
R47-R49 Symptoms and signs involving speech and voice
0.908 0.092 0.000
T79-T79 Certain early complications of trauma
0.908 0.092 0.000
M05-M14 Inflammatory polyarthropathies
0.908 0.092 0.000
Z45.2 Adjustment and management of vascular access device
0.907 0.093 0.000
S40-S49 Injuries to the shoulder and upper arm
0.907 0.093 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.905 0.095 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.905 0.095 0.000
G81 Hemiplegia
0.903 0.097 0.000
D23 Other benign neoplasms of skin
0.901 0.099 0.000
R06.8 Other and unspecified abnormalities of breathing
0.898 0.102 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.896 0.104 0.000
I69 Sequelae of cerebrovascular disease
0.896 0.104 0.000
M47.86 Other spondylosis (Lumbar region)
0.896 0.104 0.000
R09.0 Asphyxia
0.895 0.105 0.000
G56.2 Lesion of ulnar nerve
0.893 0.107 0.000
F31 Bipolar affective disorder
0.892 0.108 0.000
C25.9 Pancreas, unspecified
0.890 0.110 0.000
Z51 Other medical care
0.888 0.112 0.000
H90-H95 Other disorders of ear
0.886 0.114 0.000
H40-H42 Glaucoma
0.886 0.114 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.885 0.115 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.883 0.117 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.883 0.117 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.879 0.121 0.000
M24 Other specific joint derangements
0.876 0.124 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.875 0.125 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.875 0.125 0.000
Z51.3 Blood transfusion without reported diagnosis
0.874 0.126 0.000
Z50 Care involving use of rehabilitation procedures
0.873 0.127 0.000
D32 Benign neoplasm of meninges
0.873 0.127 0.000
I30-I52 Other forms of heart disease
0.872 0.128 0.000
H40 Glaucoma
0.868 0.132 0.000
T51 Toxic effect of alcohol
0.867 0.133 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.865 0.135 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.863 0.137 0.000
S62.3 Fracture of other metacarpal bone
0.861 0.139 0.000
G95 Other diseases of spinal cord
0.860 0.140 0.000
M10 Gout
0.860 0.140 0.000
G81.9 Hemiplegia, unspecified
0.859 0.141 0.000
M91-M94 Chondropathies
0.859 0.141 0.000
D23.1 Skin of eyelid, including canthus
0.856 0.144 0.000
H91 Other hearing loss
0.856 0.144 0.000
Z48 Other surgical follow-up care
0.855 0.145 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.854 0.146 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.854 0.146 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.852 0.148 0.000
T39.0 Salicylates
0.848 0.151 0.000
G56.0 Carpal tunnel syndrome
0.848 0.152 0.000
S62.6 Fracture of other finger
0.847 0.153 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.844 0.156 0.000
I42 Cardiomyopathy
0.843 0.157 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.841 0.159 0.000
S32 Fracture of lumbar spine and pelvis
0.841 0.159 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.841 0.159 0.000
H65-H75 Diseases of middle ear and mastoid
0.839 0.161 0.000
H40.1 Primary open-angle glaucoma
0.839 0.161 0.000
F32.1 Moderate depressive episode
0.839 0.161 0.000
D45 Polycythaemia vera
0.839 0.161 0.000
M25.50 Pain in joint (Multiple sites)
0.837 0.163 0.000
R07 Pain in throat and chest
0.835 0.165 0.000
D80-D89 Certain disorders involving the immune mechanism
0.835 0.165 0.000
C91 Lymphoid leukaemia
0.835 0.165 0.000
H91.9 Hearing loss, unspecified
0.834 0.166 0.000
T66-T78 Other and unspecified effects of external causes
0.833 0.167 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.833 0.167 0.000
M67 Other disorders of synovium and tendon
0.831 0.169 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.830 0.170 0.000
S42 Fracture of shoulder and upper arm
0.830 0.170 0.000
M25.52 Pain in joint (Upper arm)
0.829 0.171 0.000
G93 Other disorders of brain
0.828 0.172 0.000
C25.1 Body of pancreas
0.826 0.174 0.000
M10.9 Gout, unspecified
0.826 0.174 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.824 0.176 0.000
I05-I09 Chronic rheumatic heart diseases
0.820 0.180 0.000
R09.1 Pleurisy
0.820 0.180 0.000
R07.3 Other chest pain
0.819 0.181 0.000
T93 Sequelae of injuries of lower limb
0.818 0.182 0.000
I35 Nonrheumatic aortic valve disorders
0.817 0.183 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.817 0.183 0.000
G96 Other disorders of central nervous system
0.816 0.184 0.000
C15 Malignant neoplasm of oesophagus
0.816 0.184 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.814 0.186 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.812 0.187 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.812 0.188 0.000
C25.0 Head of pancreas
0.808 0.191 0.000
Z72 Problems related to lifestyle
0.807 0.193 0.000
Z48.8 Other specified surgical follow-up care
0.807 0.193 0.000
M48 Other spondylopathies
0.803 0.197 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.803 0.197 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.802 0.198 0.000
T92 Sequelae of injuries of upper limb
0.802 0.198 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.801 0.199 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.800 0.200 0.000
R47 Speech disturbances, not elsewhere classified
0.799 0.200 0.000
R06.6 Hiccough
0.799 0.201 0.000
F32.0 Mild depressive episode
0.797 0.203 0.000
R49 Voice disturbances
0.797 0.203 0.000
M22 Disorders of patella
0.796 0.204 0.000
I77 Other disorders of arteries and arterioles
0.796 0.204 0.000
R06.5 Mouth breathing
0.795 0.205 0.000
I42.9 Cardiomyopathy, unspecified
0.793 0.207 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.793 0.207 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.792 0.208 0.000
R05 Cough
0.791 0.209 0.000
S64 Injury of nerves at wrist and hand level
0.791 0.209 0.000
S62.61 Fracture of other finger (open)
0.789 0.211 0.000
M47.9 Spondylosis, unspecified
0.788 0.212 0.000
G82 Paraplegia and tetraplegia
0.788 0.212 0.000
H40.0 Glaucoma suspect
0.787 0.213 0.000
M65 Synovitis and tenosynovitis
0.787 0.213 0.000
F80-F89 Disorders of psychological development
0.786 0.213 0.000
S10-S19 Injuries to the neck
0.786 0.214 0.000
R06.4 Hyperventilation
0.784 0.216 0.000
C17 Malignant neoplasm of small intestine
0.784 0.216 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.783 0.217 0.000
I61 Intracerebral haemorrhage
0.779 0.221 0.000
F60-F69 Disorders of adult personality and behaviour
0.779 0.221 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.779 0.221 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.778 0.222 0.000
M10.99 Gout, unspecified (Site unspecified)
0.776 0.224 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.775 0.225 0.000
S20-S29 Injuries to the thorax
0.775 0.225 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.773 0.227 0.000
D70 Agranulocytosis
0.773 0.227 0.000
G40-G47 Episodic and paroxysmal disorders
0.773 0.227 0.000
H43-H45 Disorders of vitreous body and globe
0.772 0.228 0.000
M25.8 Other specified joint disorders
0.772 0.228 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.772 0.228 0.000
C91.1 Chronic lymphocytic leukaemia
0.771 0.229 0.000
G80 Infantile cerebral palsy
0.770 0.230 0.000
T63 Toxic effect of contact with venomous animals
0.769 0.231 0.000
C25.2 Tail of pancreas
0.769 0.231 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.768 0.232 0.000
D23.7 Skin of lower limb, including hip
0.768 0.232 0.000
D17 Benign lipomatous neoplasm
0.768 0.232 0.000
M40-M43 Deforming dorsopathies
0.768 0.232 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.767 0.232 0.000
D16 Benign neoplasm of bone and articular cartilage
0.767 0.233 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.767 0.233 0.000
F33 Recurrent depressive disorder
0.767 0.233 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.766 0.233 0.000
Z76 Persons encountering health services in other circumstances
0.766 0.234 0.000
M25.56 Pain in joint (Lower leg)
0.765 0.235 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.765 0.235 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.764 0.235 0.000
F43 Reaction to severe stress, and adjustment disorders
0.764 0.236 0.000
D69 Purpura and other haemorrhagic conditions
0.763 0.237 0.000
S70-S79 Injuries to the hip and thigh
0.763 0.237 0.000
D31 Benign neoplasm of eye and adnexa
0.763 0.237 0.000
S32.5 Fracture of pubis
0.762 0.238 0.000
M25.3 Other instability of joint
0.762 0.238 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.762 0.238 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.760 0.240 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.760 0.240 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.759 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.758 0.242 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.758 0.242 0.000
M24.1 Other articular cartilage disorders
0.758 0.242 0.000
D55-D59 Haemolytic anaemias
0.757 0.243 0.000
Z45.1 Adjustment and management of infusion pump
0.757 0.243 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.757 0.243 0.000
T51.0 Ethanol
0.756 0.244 0.000
T51.9 Alcohol, unspecified
0.754 0.246 0.000
R06.2 Wheezing
0.753 0.247 0.000
Z74 Problems related to care-provider dependency
0.752 0.248 0.000
D32.1 Spinal meninges
0.751 0.249 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.751 0.249 0.000
D46 Myelodysplastic syndromes
0.751 0.249 0.000
M60-M63 Disorders of muscles
0.751 0.249 0.000
Z72.1 Alcohol use
0.751 0.249 0.000
D32.9 Meninges, unspecified
0.750 0.250 0.000
Z50.5 Speech therapy
0.750 0.250 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.750 0.250 0.000
S68 Traumatic amputation of wrist and hand
0.749 0.250 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
D37.1 Stomach
0.748 0.252 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.747 0.253 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.745 0.254 0.000
T98 Sequelae of other and unspecified effects of external causes
0.745 0.255 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.744 0.256 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.744 0.256 0.000
Q80-Q89 Other congenital malformations
0.742 0.258 0.000
Z51.8 Other specified medical care
0.742 0.258 0.000
I74 Arterial embolism and thrombosis
0.742 0.258 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.742 0.258 0.000
G91 Hydrocephalus
0.741 0.259 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.739 0.261 0.000
X20-X29 Contact with venomous animals and plants
0.738 0.262 0.000
M31 Other necrotising vasculopathies
0.737 0.263 0.000
I31 Other diseases of pericardium
0.737 0.263 0.000
D50-D53 Nutritional anaemias
0.734 0.266 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.733 0.267 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.733 0.267 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.733 0.267 0.000
G95.2 Cord compression, unspecified
0.731 0.269 0.000
R09.2 Respiratory arrest
0.731 0.269 0.000
F41 Other anxiety disorders
0.730 0.270 0.000
D18 Haemangioma and lymphangioma, any site
0.729 0.271 0.000
G83 Other paralytic syndromes
0.728 0.272 0.000
W50-W64 Exposure to animate mechanical forces
0.728 0.272 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.728 0.272 0.000
S41 Open wound of shoulder and upper arm
0.728 0.272 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.727 0.273 0.000
S42.2 Fracture of upper end of humerus
0.727 0.273 0.000
Z45.8 Adjustment and management of other implanted devices
0.727 0.273 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.727 0.273 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.726 0.274 0.000
V40-V49 Car occupant injured in transport accident
0.726 0.274 0.000
M47.1 Other spondylosis with myelopathy
0.726 0.274 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.725 0.275 0.000
U51 Admission status on psychiatric patients
0.724 0.276 0.000
M25.7 Osteophyte
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
M13 Other arthritis
0.723 0.277 0.000
I62 Other nontraumatic intracranial haemorrhage
0.723 0.277 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.723 0.277 0.000
H72 Perforation of tympanic membrane
0.722 0.278 0.000
W20-W49 Exposure to inanimate mechanical forces
0.722 0.278 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.721 0.279 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.720 0.280 0.000
M34 Systemic sclerosis
0.719 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.719 0.281 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.719 0.281 0.000
R49.0 Dysphonia
0.718 0.282 0.000
H90 Conductive and sensorineural hearing loss
0.718 0.282 0.000
Z43 Attention to artificial openings
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M67.8 Other specified disorders of synovium and tendon
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.716 0.284 0.000
M24.2 Disorder of ligament
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.714 0.286 0.000
I63 Cerebral infarction
0.714 0.286 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.714 0.286 0.000
R50-R69 General symptoms and signs
0.714 0.286 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.714 0.286 0.000
C23 Malignant neoplasm of gallbladder
0.714 0.286 0.000
S32.0 Fracture of lumbar vertebra
0.714 0.286 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.714 0.286 0.000
M93 Other osteochondropathies
0.714 0.286 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.713 0.287 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.713 0.287 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.713 0.287 0.000
H20 Iridocyclitis
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
S32.3 Fracture of ilium
0.711 0.289 0.000
S60 Superficial injury of wrist and hand
0.710 0.290 0.000
F30 Manic episode
0.710 0.290 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.710 0.290 0.000
T43.9 Psychotropic drug, unspecified
0.709 0.290 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.709 0.290 0.000
T43.6 Psychostimulants with abuse potential
0.709 0.290 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.709 0.290 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.709 0.290 0.000
T90 Sequelae of injuries of head
0.708 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.707 0.293 0.000
T39.4 Antirheumatics, not elsewhere classified
0.707 0.293 0.000
T39.2 Pyrazolone derivatives
0.707 0.293 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.707 0.293 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.706 0.294 0.000
G90 Disorders of autonomic nervous system
0.706 0.294 0.000
D23.3 Skin of other and unspecified parts of face
0.706 0.294 0.000
D72 Other disorders of white blood cells
0.706 0.294 0.000
S32.50 Fracture of pubis (closed)
0.706 0.294 0.000
D24 Benign neoplasm of breast
0.705 0.295 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.705 0.295 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.705 0.295 0.000
G92 Toxic encephalopathy
0.705 0.295 0.000
I77.1 Stricture of artery
0.705 0.295 0.000
M05 Seropositive rheumatoid arthritis
0.705 0.295 0.000
Q60-Q64 Congenital malformations of the urinary system
0.705 0.295 0.000
R02 Gangrene, not elsewhere classified
0.704 0.296 0.000
M47.82 Other spondylosis (Cervical region)
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.703 0.297 0.000
M22.8 Other disorders of patella
0.702 0.298 0.000
G95.1 Vascular myelopathies
0.702 0.298 0.000
D86 Sarcoidosis
0.701 0.299 0.000
D37.2 Small intestine
0.701 0.299 0.000
C22.0 Liver cell carcinoma
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
F38 Other mood [affective] disorders
0.700 0.300 0.000
F34 Persistent mood [affective] disorders
0.700 0.300 0.000
F39 Unspecified mood [affective] disorder
0.700 0.300 0.000
M47.89 Other spondylosis (Site unspecified)
0.700 0.300 0.000
S62.5 Fracture of thumb
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.301 0.000
M47.2 Other spondylosis with radiculopathy
0.699 0.301 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.699 0.301 0.000
D26 Other benign neoplasms of uterus
0.699 0.301 0.000
D37.7 Other digestive organs
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.698 0.302 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
S65 Injury of blood vessels at wrist and hand level
0.698 0.302 0.000
U80 Agent resistant to penicillin and related antibiotics
0.698 0.302 0.000
Z50.2 Alcohol rehabilitation
0.698 0.302 0.000
Z51.9 Medical care, unspecified
0.697 0.303 0.000
G96.0 Cerebrospinal fluid leak
0.696 0.304 0.000
C25.8 Overlapping lesion of pancreas
0.696 0.304 0.000
C25.7 Other parts of pancreas
0.696 0.304 0.000
C25.4 Endocrine pancreas
0.696 0.304 0.000
C25.3 Pancreatic duct
0.696 0.304 0.000
H10-H13 Disorders of conjunctiva
0.695 0.305 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.694 0.306 0.000
C22.1 Intrahepatic bile duct carcinoma
0.693 0.307 0.000
Z71.8 Other specified counselling
0.693 0.307 0.000
M94 Other disorders of cartilage
0.692 0.308 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
M49 Spondylopathies in diseases classified elsewhere
0.689 0.311 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.689 0.311 0.000
R06.7 Sneezing
0.688 0.312 0.000
R06.3 Periodic breathing
0.688 0.312 0.000
Z50.1 Other physical therapy
0.688 0.312 0.000
C15.9 Oesophagus, unspecified
0.687 0.313 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.687 0.313 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.687 0.313 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.687 0.313 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.687 0.313 0.000
Z29 Need for other prophylactic measures
0.687 0.313 0.000
I49 Other cardiac arrhythmias
0.687 0.313 0.000
G93.2 Benign intracranial hypertension
0.687 0.313 0.000
I44 Atrioventricular and left bundle-branch block
0.686 0.313 0.000
I00-I02 Acute rheumatic fever
0.686 0.314 0.000
T92.1 Sequelae of fracture of arm
0.685 0.315 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.685 0.315 0.000
Z50.8 Care involving use of rehabilitation procedures
0.685 0.315 0.000
I70 Atherosclerosis
0.684 0.316 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.684 0.316 0.000
M33 Dermatopolymyositis
0.684 0.316 0.000
M32 Systemic lupus erythematosus
0.684 0.316 0.000
I35.8 Other aortic valve disorders
0.684 0.316 0.000
I42.2 Other hypertrophic cardiomyopathy
0.683 0.317 0.000
R06.1 Stridor
0.683 0.317 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.683 0.317 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.683 0.317 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.682 0.318 0.000
H69 Other disorders of Eustachian tube
0.682 0.318 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.682 0.318 0.000
T78 Adverse effects, not elsewhere classified
0.681 0.319 0.000
T40.2 Other opioids
0.681 0.319 0.000
D32.0 Cerebral meninges
0.680 0.319 0.000
R09.3 Abnormal sputum
0.680 0.320 0.000
H44 Disorders of globe
0.680 0.320 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.680 0.320 0.000
H40.5 Glaucoma secondary to other eye disorders
0.679 0.321 0.000
S62.7 Multiple fractures of fingers
0.678 0.322 0.000
S62.4 Multiple fractures of metacarpal bones
0.678 0.322 0.000
S62.1 Fracture of other carpal bone(s)
0.678 0.322 0.000
T59 Toxic effect of other gases, fumes and vapours
0.678 0.322 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.678 0.322 0.000
T91 Sequelae of injuries of neck and trunk
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
G93.4 Encephalopathy, unspecified
0.677 0.323 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.676 0.323 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.676 0.324 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.676 0.324 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.675 0.325 0.000
M25.2 Flail joint
0.674 0.325 0.000
M25.1 Fistula of joint
0.674 0.325 0.000
M25.0 Haemarthrosis
0.674 0.325 0.000
D23.0 Skin of lip
0.674 0.326 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
I42.0 Dilated cardiomyopathy
0.674 0.326 0.000
X50-X57 Overexertion, travel and privation
0.673 0.327 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.673 0.327 0.000
G47 Sleep disorders
0.673 0.327 0.000
T65 Toxic effect of other and unspecified substances
0.673 0.327 0.000
T62 Toxic effect of other noxious substances eaten as food
0.673 0.327 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.673 0.327 0.000
T60 Toxic effect of pesticides
0.673 0.327 0.000
T57 Toxic effect of other inorganic substances
0.673 0.327 0.000
T56 Toxic effect of metals
0.673 0.327 0.000
T54 Toxic effect of corrosive substances
0.673 0.327 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.673 0.327 0.000
T52 Toxic effect of organic solvents
0.673 0.327 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.673 0.327 0.000
T58 Toxic effect of carbon monoxide
0.673 0.327 0.000
T55 Toxic effect of soaps and detergents
0.673 0.327 0.000
R47.8 Other and unspecified speech disturbances
0.673 0.327 0.000
I69.3 Sequelae of cerebral infarction
0.672 0.327 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.672 0.328 0.000
D19 Benign neoplasm of mesothelial tissue
0.672 0.328 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.672 0.328 0.000
Z44 Fitting and adjustment of external prosthetic device
0.672 0.328 0.000
I35.1 Aortic (valve) insufficiency
0.672 0.328 0.000
M25.59 Pain in joint (Site unspecified)
0.672 0.328 0.000
D13.1 Stomach
0.672 0.328 0.000
C21 Malignant neoplasm of anus and anal canal
0.671 0.329 0.000
S67 Crushing injury of wrist and hand
0.670 0.330 0.000
T79.8 Other early complications of trauma
0.670 0.330 0.000
C81 Hodgkin's disease
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
G30-G32 Other degenerative diseases of the nervous system
0.669 0.331 0.000
F99-F99 Unspecified mental disorder
0.669 0.331 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
G93.3 Postviral fatigue syndrome
0.667 0.333 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.667 0.333 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.667 0.333 0.000
T46.7 Peripheral vasodilators
0.667 0.333 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.667 0.333 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.667 0.333 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.667 0.333 0.000
T46.1 Calcium-channel blockers
0.667 0.333 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.667 0.333 0.000
I07 Rheumatic tricuspid valve diseases
0.666 0.333 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.666 0.334 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.666 0.334 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.665 0.335 0.000
G52 Disorders of other cranial nerves
0.665 0.335 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.665 0.335 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.664 0.335 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.664 0.336 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.664 0.336 0.000
M11 Other crystal arthropathies
0.664 0.336 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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