TreeWAS – Variant ID: rs73001065

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K76.0 Fatty (change of) liver, not elsewhere classified	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
K76 Other diseases of liver	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
K70 Alcoholic liver disease	0.995	0.005	0.000
Chapter XI Diseases of the digestive system	0.987	0.013	0.000
K74 Fibrosis and cirrhosis of liver	0.987	0.013	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.986	0.014	0.000
K74.6 Other and unspecified cirrhosis of liver	0.980	0.020	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.977	0.023	0.000
Chapter VII Diseases of the eye and adnexa	0.975	0.025	0.000
H53-H54 Visual disturbances and blindness	0.972	0.028	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.966	0.034	0.000
W00-W19 Falls	0.965	0.035	0.000
H53 Visual disturbances	0.964	0.036	0.000
E11.3 With ophthalmic complications	0.958	0.042	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.951	0.049	0.000
K70.3 Alcoholic cirrhosis of liver	0.942	0.058	0.000
E20-E35 Disorders of other endocrine glands	0.941	0.059	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.939	0.061	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.932	0.068	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.932	0.068	0.000
E23 Hypofunction and other disorders of pituitary gland	0.918	0.082	0.000
H53.8 Other visual disturbances	0.918	0.082	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.918	0.082	0.000
H30-H36 Disorders of choroid and retina	0.913	0.087	0.000
Chapter I Certain infectious and parasitic diseases	0.912	0.088	0.000
K76.6 Portal hypertension	0.911	0.089	0.000
Y42.7 Androgens and anabolic congeners	0.907	0.093	0.000
Chapter IX Diseases of the circulatory system	0.905	0.095	0.000
S90-S99 Injuries to the ankle and foot	0.903	0.097	0.000
K70.4 Alcoholic hepatic failure	0.901	0.099	0.000
H53.4 Visual field defects	0.900	0.100	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.896	0.104	0.000
K70.9 Alcoholic liver disease, unspecified	0.892	0.108	0.000
H54 Blindness and low vision	0.891	0.109	0.000
Q50-Q56 Congenital malformations of genital organs	0.886	0.114	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.884	0.116	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.881	0.119	0.000
E14 Unspecified diabetes mellitus	0.878	0.122	0.000
H53.2 Diplopia	0.877	0.123	0.000
K50-K52 Noninfective enteritis and colitis	0.877	0.123	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.874	0.126	0.000
Y40 Systemic antibiotics	0.871	0.129	0.000
B35-B49 Mycoses	0.871	0.129	0.000
W13 Fall from, out of or through building or structure	0.870	0.130	0.000
K75 Other inflammatory liver diseases	0.867	0.133	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.867	0.133	0.000
E23.2 Diabetes insipidus	0.864	0.136	0.000
O42 Premature rupture of membranes	0.863	0.137	0.000
K51 Ulcerative colitis	0.862	0.138	0.000
S10-S19 Injuries to the neck	0.858	0.142	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.856	0.144	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.851	0.149	0.000
S50-S59 Injuries to the elbow and forearm	0.850	0.150	0.000
I85 Oesophageal varices	0.846	0.154	0.000
H36 Retinal disorders in diseases classified elsewhere	0.844	0.156	0.000
H35 Other retinal disorders	0.844	0.156	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.843	0.157	0.000
I10-I15 Hypertensive diseases	0.843	0.157	0.000
I85.9 Oesophageal varices without bleeding	0.840	0.160	0.000
I60-I69 Cerebrovascular diseases	0.840	0.160	0.000
W50-W64 Exposure to animate mechanical forces	0.839	0.161	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.833	0.167	0.000
H55-H59 Other disorders of eye and adnexa	0.833	0.167	0.000
O42.9 Premature rupture of membranes, unspecified	0.830	0.170	0.000
T43.2 Other and unspecified antidepressants	0.826	0.174	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.826	0.174	0.000
O85-O92 Complications predominantly related to the puerperium	0.826	0.174	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.824	0.176	0.000
W17 Other fall from one level to another	0.822	0.178	0.000
K75.8 Other specified inflammatory liver diseases	0.820	0.180	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.820	0.180	0.000
H35.8 Other specified retinal disorders	0.820	0.180	0.000
B37 Candidiasis	0.818	0.182	0.000
I11 Hypertensive heart disease	0.816	0.184	0.000
K70.1 Alcoholic hepatitis	0.811	0.189	0.000
K51.2 Ulcerative (chronic) proctitis	0.811	0.189	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.810	0.190	0.000
E23.0 Hypopituitarism	0.809	0.191	0.000
E14.9 Without complications	0.807	0.193	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.806	0.194	0.000
K76.9 Liver disease, unspecified	0.805	0.195	0.000
W20-W49 Exposure to inanimate mechanical forces	0.804	0.196	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.804	0.196	0.000
H54.4 Blindness, one eye	0.803	0.197	0.000
W13.9 Unspecified place	0.802	0.198	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.802	0.198	0.000
Y52 Agents primarily affecting the cardiovascular system	0.800	0.200	0.000
S40-S49 Injuries to the shoulder and upper arm	0.800	0.200	0.000
I69 Sequelae of cerebrovascular disease	0.799	0.201	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.796	0.204	0.000
X10-X19 Contact with heat and hot substances	0.795	0.205	0.000
B25-B34 Other viral diseases	0.795	0.205	0.000
H36.0 Diabetic retinopathy	0.794	0.206	0.000
Y00-Y09 Assault	0.793	0.207	0.000
Y40.8 Other systemic antibiotics	0.790	0.210	0.000
W19 Unspecified fall	0.790	0.210	0.000
K74.0 Hepatic fibrosis	0.789	0.211	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.789	0.211	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.787	0.213	0.000
T79-T79 Certain early complications of trauma	0.785	0.215	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.782	0.218	0.000
I67 Other cerebrovascular diseases	0.779	0.221	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.775	0.225	0.000
T42.4 Benzodiazepines	0.774	0.226	0.000
S31 Open wound of abdomen, lower back and pelvis	0.771	0.229	0.000
Y44 Agents primarily affecting blood constituents	0.771	0.229	0.000
S51 Open wound of forearm	0.770	0.230	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.770	0.230	0.000
B99-B99 Other infectious diseases	0.769	0.231	0.000
O44 Placenta praevia	0.765	0.235	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.765	0.235	0.000
S90 Superficial injury of ankle and foot	0.764	0.236	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.764	0.236	0.000
T00-T07 Injuries involving multiple body regions	0.762	0.238	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.761	0.239	0.000
W10 Fall on and from stairs and steps	0.761	0.239	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.760	0.240	0.000
E11.2 With renal complications	0.760	0.240	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.759	0.241	0.000
E28 Ovarian dysfunction	0.758	0.241	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.757	0.243	0.000
E13 Other specified diabetes mellitus	0.756	0.244	0.000
E11.8 With unspecified complications	0.756	0.244	0.000
S12 Fracture of neck	0.755	0.245	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.752	0.248	0.000
I67.9 Cerebrovascular disease, unspecified	0.750	0.250	0.000
Q51 Congenital malformations of uterus and cervix	0.750	0.250	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.748	0.252	0.000
H54.7 Unspecified visual loss	0.748	0.252	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.748	0.252	0.000
W19.4 Street and highway	0.746	0.254	0.000
E11.0 With coma	0.745	0.255	0.000
I61 Intracerebral haemorrhage	0.745	0.255	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.738	0.262	0.000
O00-O08 Pregnancy with abortive outcome	0.733	0.265	0.003
E23.7 Disorder of pituitary gland, unspecified	0.735	0.265	0.000
I69.3 Sequelae of cerebral infarction	0.733	0.267	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.732	0.268	0.000
V40-V49 Car occupant injured in transport accident	0.731	0.268	0.000
X50-X57 Overexertion, travel and privation	0.731	0.268	0.000
Y48 Anaesthetics and therapeutic gases	0.731	0.269	0.000
O86 Other puerperal infections	0.731	0.269	0.000
K51.8 Other ulcerative colitis	0.730	0.270	0.000
I86 Varicose veins of other sites	0.729	0.270	0.000
K70.0 Alcoholic fatty liver	0.729	0.271	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.729	0.271	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.729	0.271	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.728	0.272	0.000
H53.9 Visual disturbance, unspecified	0.728	0.272	0.000
E11.4 With neurological complications	0.728	0.272	0.000
E34 Other endocrine disorders	0.727	0.273	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.725	0.275	0.000
E10 Insulin-dependent diabetes mellitus	0.724	0.276	0.000
E11.1 With ketoacidosis	0.724	0.276	0.000
S92 Fracture of foot, except ankle	0.723	0.277	0.000
A65-A69 Other spirochaetal diseases	0.722	0.278	0.000
K51.5 Mucosal proctocolitis	0.722	0.278	0.000
B34 Viral infection of unspecified site	0.722	0.278	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.720	0.280	0.000
X60-X84 Intentional self-harm	0.719	0.281	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.719	0.281	0.000
H55 Nystagmus and other irregular eye movements	0.718	0.282	0.000
K76.7 Hepatorenal syndrome	0.717	0.283	0.000
K76.5 Hepatic veno-occlusive disease	0.717	0.283	0.000
K76.4 Peliosis hepatis	0.717	0.283	0.000
K76.3 Infarction of liver	0.717	0.283	0.000
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283	0.000
K76.1 Chronic passive congestion of liver	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.284	0.000
Y10-Y34 Event of undetermined intent	0.716	0.284	0.000
X85-X99 Assault	0.716	0.284	0.000
X30-X39 Exposure to forces of nature	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284	0.000
W75-W84 Other accidental threats to breathing	0.716	0.284	0.000
W65-W74 Accidental drowning and submersion	0.716	0.284	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.284	0.000
V95-V97 Air and space transport accidents	0.716	0.284	0.000
V90-V94 Water transport accidents	0.716	0.284	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.284	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284	0.000
V01-V09 Pedestrian injured in transport accident	0.716	0.284	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.716	0.284	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.716	0.284	0.000
O43 Placental disorders	0.715	0.285	0.000
B37.8 Candidiasis of other sites	0.715	0.285	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.714	0.286	0.000
O40 Polyhydramnios	0.713	0.287	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.713	0.287	0.000
Chapter V Mental and behavioural disorders	0.713	0.287	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.711	0.289	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.711	0.289	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.708	0.292	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.708	0.292	0.000
E24 Cushing's syndrome	0.708	0.292	0.000
K74.4 Secondary biliary cirrhosis	0.707	0.293	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.707	0.293	0.000
K74.1 Hepatic sclerosis	0.707	0.293	0.000
O00 Ectopic pregnancy	0.706	0.293	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.707	0.293	0.000
Y59 Other and unspecified vaccines and biological substances	0.707	0.293	0.000
Y58 Bacterial vaccines	0.707	0.293	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.707	0.293	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.707	0.293	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.707	0.293	0.000
S42 Fracture of shoulder and upper arm	0.706	0.294	0.000
H54.6 Unqualified visual loss, one eye	0.706	0.294	0.000
K14 Diseases of tongue	0.705	0.295	0.000
W08 Fall involving other furniture	0.704	0.296	0.000
I85.0 Oesophageal varices with bleeding	0.704	0.296	0.000
B37.0 Candidal stomatitis	0.704	0.296	0.000
Y45.1 Salicylates	0.704	0.296	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.703	0.297	0.000
E40-E46 Malnutrition	0.702	0.298	0.000
T40.4 Other synthetic narcotics	0.701	0.299	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.701	0.299	0.000
T33-T35 Frostbite	0.700	0.300	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.700	0.300	0.000
H35.9 Retinal disorder, unspecified	0.699	0.301	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.698	0.302	0.000
E11.6 With other specified complications	0.697	0.303	0.000
Y57 Other and unspecified drugs and medicaments	0.694	0.306	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.693	0.307	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.693	0.307	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.693	0.307	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.693	0.307	0.000
T36 Poisoning by systemic antibiotics	0.693	0.307	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.693	0.307	0.000
Q55 Other congenital malformations of male genital organs	0.693	0.307	0.000
K76.8 Other specified diseases of liver	0.693	0.307	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.692	0.308	0.000
W15 Fall from cliff	0.692	0.308	0.000
W14 Fall from tree	0.692	0.308	0.000
W12 Fall on and from scaffolding	0.692	0.308	0.000
W11 Fall on and from ladder	0.692	0.308	0.000
W09 Fall involving playground equipment	0.692	0.308	0.000
W05 Fall involving wheelchair	0.692	0.308	0.000
W04 Fall while being carried or supported by other persons	0.692	0.308	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.692	0.308	0.000
W00 Fall on same level involving ice and snow	0.692	0.308	0.000
H53.6 Night blindness	0.691	0.309	0.000
H53.5 Colour vision deficiencies	0.691	0.309	0.000
H53.3 Other disorders of binocular vision	0.691	0.309	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.691	0.309	0.000
Chapter VIII Diseases of the ear and mastoid process	0.690	0.310	0.000
Y40.0 Penicillins	0.690	0.310	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.688	0.312	0.000
E11.5 With peripheral circulatory complications	0.687	0.313	0.000
Y95 Nosocomial condition	0.686	0.314	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.685	0.315	0.000
W17.5 Trade and service area	0.685	0.315	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.685	0.315	0.000
B49 Unspecified mycosis	0.684	0.316	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.684	0.316	0.000
O34.4 Maternal care for other abnormalities of cervix	0.684	0.316	0.000
K73 Chronic hepatitis, not elsewhere classified	0.683	0.316	0.000
W18 Other fall on same level	0.683	0.317	0.000
O00.1 Tubal pregnancy	0.682	0.318	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.682	0.318	0.000
Q35-Q37 Cleft lip and cleft palate	0.682	0.318	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.682	0.318	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.680	0.320	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.679	0.321	0.000
Q80-Q89 Other congenital malformations	0.677	0.323	0.000
K12 Stomatitis and related lesions	0.677	0.323	0.000
V80-V89 Other land transport accidents	0.676	0.324	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.675	0.325	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.675	0.325	0.000
E32 Diseases of thymus	0.675	0.325	0.000
E31 Polyglandular dysfunction	0.675	0.325	0.000
E30 Disorders of puberty, not elsewhere classified	0.675	0.325	0.000
E26 Hyperaldosteronism	0.675	0.325	0.000
E25 Adrenogenital disorders	0.675	0.325	0.000
E20 Hypoparathyroidism	0.675	0.325	0.000
T43.9 Psychotropic drug, unspecified	0.674	0.326	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.674	0.326	0.000
T43.6 Psychostimulants with abuse potential	0.674	0.326	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.674	0.326	0.000
B44 Aspergillosis	0.672	0.328	0.000
S51.7 Multiple open wounds of forearm	0.672	0.328	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.670	0.330	0.000
S40 Superficial injury of shoulder and upper arm	0.669	0.330	0.000
Y42.9 Other and unspecified hormone antagonists	0.668	0.331	0.000
Y42.4 Oral contraceptives	0.668	0.331	0.000
Y42.2 Antithyroid drugs	0.668	0.331	0.000
Y42.1 Thyroid hormones and substitutes	0.668	0.331	0.000
W20 Struck by thrown, projected or falling object	0.668	0.332	0.000
W07 Fall involving chair	0.668	0.332	0.000
B99 Other and unspecified infectious diseases	0.668	0.332	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.667	0.332	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333	0.000
K75.9 Inflammatory liver disease, unspecified	0.667	0.333	0.000
B50-B64 Protozoal diseases	0.667	0.333	0.000
Q23 Congenital malformations of aortic and mitral valves	0.666	0.334	0.000
S36 Injury of intra-abdominal organs	0.666	0.334	0.000
B36 Other superficial mycoses	0.664	0.336	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.663	0.337	0.000
S50 Superficial injury of forearm	0.663	0.337	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.663	0.337	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.662	0.338	0.000
T51 Toxic effect of alcohol	0.662	0.338	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.660	0.340	0.000
T40.6 Other and unspecified narcotics	0.660	0.340	0.000
E23.6 Other disorders of pituitary gland	0.658	0.341	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.658	0.341	0.000
E23.1 Drug-induced hypopituitarism	0.658	0.341	0.000
O45 Premature separation of placenta [abruptio placentae]	0.658	0.342	0.000
O33 Maternal care for known or suspected disproportion	0.658	0.342	0.000
O31 Complications specific to multiple gestation	0.658	0.342	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.658	0.342	0.000
K14.0 Glossitis	0.658	0.342	0.000
Q24 Other congenital malformations of heart	0.657	0.343	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.656	0.343	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.656	0.344	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.655	0.345	0.000
H30 Chorioretinal inflammation	0.655	0.345	0.000
H31 Other disorders of choroid	0.654	0.346	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.654	0.346	0.000
Q00-Q07 Congenital malformations of the nervous system	0.654	0.346	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.654	0.346	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.654	0.346	0.000
A75-A79 Rickettsioses	0.654	0.346	0.000
A70-A74 Other diseases caused by chlamydiae	0.654	0.346	0.000
A20-A28 Certain zoonotic bacterial diseases	0.654	0.346	0.000
A15-A19 Tuberculosis	0.654	0.346	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.653	0.346	0.000
I82 Other venous embolism and thrombosis	0.653	0.347	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.653	0.347	0.000
I81 Portal vein thrombosis	0.653	0.347	0.000
S14 Injury of nerves and spinal cord at neck level	0.653	0.347	0.000
W44 Foreign body entering into or through eye or natural orifice	0.651	0.349	0.000
A00-A09 Intestinal infectious diseases	0.649	0.351	0.000
W17.4 Street and highway	0.649	0.351	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.649	0.351	0.000
I00-I02 Acute rheumatic fever	0.649	0.351	0.000
Q66 Congenital deformities of feet	0.648	0.352	0.000
S98 Traumatic amputation of ankle and foot	0.648	0.352	0.000
S97 Crushing injury of ankle and foot	0.648	0.352	0.000
S95 Injury of blood vessels at ankle and foot level	0.648	0.352	0.000
S94 Injury of nerves at ankle and foot level	0.648	0.352	0.000
X20-X29 Contact with venomous animals and plants	0.647	0.353	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.647	0.353	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.647	0.353	0.000
O87 Venous complications in the puerperium	0.645	0.355	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.643	0.357	0.000
S51.0 Open wound of elbow	0.643	0.357	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.643	0.357	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.643	0.357	0.000
O34.6 Maternal care for abnormality of vagina	0.643	0.357	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.643	0.357	0.000
O34.3 Maternal care for cervical incompetence	0.643	0.357	0.000
O34.0 Maternal care for congenital malformation of uterus	0.643	0.357	0.000
Y52.1 Calcium-channel blockers	0.643	0.357	0.000
Y04 Assault by bodily force	0.642	0.358	0.000
K10 Other diseases of jaws	0.640	0.360	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.640	0.360	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.639	0.361	0.000
H54.5 Low vision, one eye	0.639	0.361	0.000
H54.3 Unqualified visual loss, both eyes	0.639	0.361	0.000
H54.2 Low vision, both eyes	0.639	0.361	0.000
H54.1 Blindness, one eye, low vision, other eye	0.639	0.361	0.000
S91 Open wound of ankle and foot	0.639	0.361	0.000
H35.2 Other proliferative retinopathy	0.639	0.361	0.000
V10-V19 Pedal cyclist injured in transport accident	0.638	0.362	0.000
B15-B19 Viral hepatitis	0.638	0.362	0.000
B37.9 Candidiasis, unspecified	0.638	0.362	0.000
S56 Injury of muscle and tendon at forearm level	0.637	0.363	0.000
Q51.2 Other doubling of uterus	0.637	0.363	0.000
Chapter VI Diseases of the nervous system	0.637	0.363	0.000
O47 False labour	0.636	0.363	0.000
Q78 Other osteochondrodysplasias	0.636	0.364	0.000
K74.5 Biliary cirrhosis, unspecified	0.636	0.364	0.000
H43-H45 Disorders of vitreous body and globe	0.636	0.364	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.635	0.365	0.000
Q53 Undescended testicle	0.635	0.365	0.000
Q52 Other congenital malformations of female genitalia	0.635	0.365	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.635	0.365	0.000
W10.8 Other specified place	0.635	0.365	0.000
I80 Phlebitis and thrombophlebitis	0.635	0.365	0.000
O86.2 Urinary tract infection following delivery	0.634	0.366	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.632	0.368	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.632	0.368	0.000
S37 Injury of urinary and pelvic organs	0.632	0.368	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.632	0.368	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.632	0.368	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.632	0.368	0.000
H10-H13 Disorders of conjunctiva	0.631	0.369	0.000
Q76 Congenital malformations of spine and bony thorax	0.631	0.369	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.630	0.370	0.000
W02.9 Unspecified place	0.630	0.370	0.000
E14.8 With unspecified complications	0.630	0.370	0.000
E14.7 With multiple complications	0.630	0.370	0.000
E14.6 With other specified complications	0.630	0.370	0.000
E14.5 With peripheral circulatory complications	0.630	0.370	0.000
E14.4 With neurological complications	0.630	0.370	0.000
E14.2 Withrenal complications	0.630	0.370	0.000
E14.1 With ketoacidosis	0.630	0.370	0.000
E14.0 With coma	0.630	0.370	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.629	0.371	0.000
V20-V29 Motorcycle rider injured in transport accident	0.629	0.371	0.000
Y46.2 Hydantoin derivatives	0.629	0.371	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.627	0.373	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.627	0.373	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.627	0.373	0.000
T42.3 Barbiturates	0.627	0.373	0.000
T42.2 Succinimides and oxazolidinediones	0.627	0.373	0.000
T42.1 Iminostilbenes	0.627	0.373	0.000
T42.0 Hydantoin derivatives	0.627	0.373	0.000
B95-B98 Bacterial, viral and other infectious agents	0.626	0.374	0.000
E28.2 Polycystic ovarian syndrome	0.625	0.375	0.000
Y40.7 Antifungal antibiotics, systemically used	0.624	0.375	0.000
Y40.6 Rifamycins	0.624	0.375	0.000
Y40.5 Aminoglycosides	0.624	0.375	0.000
Y40.4 Tetracyclines	0.624	0.375	0.000
Y40.2 Chloramphenicol group	0.624	0.375	0.000
S70-S79 Injuries to the hip and thigh	0.624	0.375	0.000
B48 Other mycoses, not elsewhere classified	0.624	0.375	0.000
B47 Mycetoma	0.624	0.375	0.000
B46 Zygomycosis	0.624	0.375	0.000
B45 Cryptococcosis	0.624	0.375	0.000
B43 Chromomycosis and phaeomycotic abscess	0.624	0.375	0.000
B42 Sporotrichosis	0.624	0.375	0.000
B41 Paracoccidioidomycosis	0.624	0.375	0.000
B40 Blastomycosis	0.624	0.375	0.000
B39 Histoplasmosis	0.624	0.375	0.000
B38 Coccidioidomycosis	0.624	0.375	0.000
W13.8 Other specified place	0.624	0.376	0.000
W13.0 Home	0.624	0.376	0.000
W13.7 Farm	0.624	0.376	0.000
W13.6 Industrial and construction area	0.624	0.376	0.000
W13.5 Trade and service area	0.624	0.376	0.000
W13.4 Street and highway	0.624	0.376	0.000
W13.3 Sports and athletics area	0.624	0.376	0.000
W13.2 School, other institution and public administrative area	0.624	0.376	0.000
W13.1 Residential institution	0.624	0.376	0.000
S99 Other and unspecified injuries of ankle and foot	0.623	0.376	0.000
T39.0 Salicylates	0.623	0.377	0.000
B65-B83 Helminthiases	0.622	0.378	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.622	0.378	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.622	0.378	0.000
K75.2 Nonspecific reactive hepatitis	0.622	0.378	0.000
K75.1 Phlebitis of portal vein	0.622	0.378	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.621	0.379	0.000
B37.3 Candidiasis of vulva and vagina	0.621	0.379	0.000
A80-A89 Viral infections of the central nervous system	0.620	0.380	0.000
S10 Superficial injury of neck	0.620	0.380	0.000
H53.1 Subjective visual disturbances	0.620	0.380	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.620	0.380	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.619	0.380	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.619	0.381	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.619	0.381	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.618	0.382	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.618	0.382	0.000
H35.3 Degeneration of macula and posterior pole	0.618	0.382	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.617	0.383	0.000
Y44.2 Anticoagulants	0.617	0.383	0.000
S12.1 Fracture of second cervical vertebra	0.616	0.384	0.000
O41 Other disorders of amniotic fluid and membranes	0.616	0.384	0.000
S93.0 Dislocation of ankle joint	0.616	0.384	0.000
S17 Crushing injury of neck	0.615	0.385	0.000
S15 Injury of blood vessels at neck level	0.615	0.385	0.000
S11 Open wound of neck	0.615	0.385	0.000
S18 Traumatic amputation at neck level	0.615	0.385	0.000
S16 Injury of muscle and tendon at neck level	0.615	0.385	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.615	0.385	0.000
K12.1 Other forms of stomatitis	0.615	0.385	0.000
E50-E64 Other nutritional deficiencies	0.614	0.386	0.000
G20-G26 Extrapyramidal and movement disorders	0.613	0.387	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.611	0.389	0.000
Y45.8 Other analgesics and antipyretics	0.611	0.389	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.610	0.389	0.000
S31.0 Open wound of lower back and pelvis	0.610	0.390	0.000
S90.0 Contusion of ankle	0.610	0.390	0.000
S59 Other and unspecified injuries of forearm	0.609	0.391	0.000
S58 Traumatic amputation of forearm	0.609	0.391	0.000
S57 Crushing injury of forearm	0.609	0.391	0.000
S55 Injury of blood vessels at forearm level	0.609	0.391	0.000
S54 Injury of nerves at forearm level	0.609	0.391	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.609	0.391	0.000
I86.8 Varicose veins of other specified sites	0.609	0.391	0.000
B35 Dermatophytosis	0.608	0.392	0.000
Q54 Hypospadias	0.607	0.393	0.000
T02 Fractures involving multiple body regions	0.607	0.393	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.607	0.393	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.605	0.395	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations