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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73040424
log Bayes Factor = 7.46879
Chromosome 12   position 5,665,454  (GRCh37) Explore rs73040424 on Ensembl!
Variant rs73040424 is part of Cluster X0121

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
T81 Complications of procedures, not elsewhere classified
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.978 0.022 0.000
S40-S49 Injuries to the shoulder and upper arm
0.974 0.026 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.972 0.028 0.000
O72 Postpartum haemorrhage
0.972 0.028 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.967 0.033 0.000
O63 Long labour
0.960 0.040 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.959 0.041 0.000
Chapter XIV Diseases of the genitourinary system
0.959 0.041 0.000
Chapter VIII Diseases of the ear and mastoid process
0.958 0.042 0.000
N17-N19 Renal failure
0.955 0.045 0.000
O80-O84 Delivery
0.954 0.046 0.000
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.952 0.048 0.000
Chapter XXI Factors influencing health status and contact with health services
0.948 0.052 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.944 0.056 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.943 0.057 0.000
N75 Diseases of Bartholin's gland
0.941 0.059 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.935 0.065 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.933 0.067 0.000
N00-N08 Glomerular diseases
0.930 0.070 0.000
S42 Fracture of shoulder and upper arm
0.929 0.071 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.924 0.076 0.000
Chapter X Diseases of the respiratory system
0.922 0.078 0.000
O63.1 Prolonged second stage (of labour)
0.921 0.079 0.000
E00-E07 Disorders of thyroid gland
0.921 0.079 0.000
N19 Unspecified renal failure
0.921 0.079 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
N75.0 Cyst of Bartholin's gland
0.917 0.083 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.917 0.083 0.000
H90-H95 Other disorders of ear
0.916 0.084 0.000
O36 Maternal care for other known or suspected foetal problems
0.914 0.086 0.000
N18 Chronic renal failure
0.914 0.086 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.914 0.086 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.913 0.087 0.000
Z49 Care involving dialysis
0.913 0.087 0.000
S42.2 Fracture of upper end of humerus
0.910 0.090 0.000
N75.1 Abscess of Bartholin's gland
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.905 0.095 0.000
O82 Single delivery by Caesarean section
0.903 0.097 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.902 0.098 0.000
S42.20 Fracture of upper end of humerus (closed)
0.896 0.104 0.000
J00-J06 Acute upper respiratory infections
0.895 0.105 0.000
O72.1 Other immediate postpartum haemorrhage
0.892 0.108 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.887 0.113 0.000
Z45 Adjustment and management of implanted device
0.882 0.118 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.879 0.121 0.000
O85-O92 Complications predominantly related to the puerperium
0.879 0.121 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.876 0.124 0.000
E10-E14 Diabetes mellitus
0.873 0.127 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.870 0.130 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.870 0.130 0.000
H60-H62 Diseases of external ear
0.868 0.132 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.867 0.133 0.000
Z37 Outcome of delivery
0.866 0.134 0.000
J09-J18 Influenza and pneumonia
0.865 0.135 0.000
E27 Other disorders of adrenal gland
0.865 0.135 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.864 0.136 0.000
Y83.8 Other surgical procedures
0.864 0.136 0.000
V10-V19 Pedal cyclist injured in transport accident
0.864 0.136 0.000
E89.0 Postprocedural hypothyroidism
0.863 0.137 0.000
Z41 Procedures for purposes other than remedying health state
0.862 0.138 0.000
E87.5 Hyperkalaemia
0.861 0.139 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.860 0.140 0.000
Z37.0 Single live birth
0.860 0.140 0.000
O82.0 Delivery by elective Caesarean section
0.857 0.143 0.000
Z45.2 Adjustment and management of vascular access device
0.855 0.145 0.000
Y45.0 Opioids and related analgesics
0.853 0.147 0.000
E83 Disorders of mineral metabolism
0.852 0.148 0.000
E04 Other non-toxic goitre
0.852 0.148 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.850 0.150 0.000
H93 Other disorders of ear, not elsewhere classified
0.846 0.154 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.846 0.154 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.844 0.156 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.844 0.156 0.000
Z42 Follow-up care involving plastic surgery
0.843 0.157 0.000
N18.9 Chronic renal failure, unspecified
0.843 0.157 0.000
O36.8 Maternal care for other specified foetal problems
0.842 0.158 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.839 0.161 0.000
A30-A49 Other bacterial diseases
0.838 0.162 0.000
Z49.1 Extracorporeal dialysis
0.835 0.165 0.000
J60-J70 Lung diseases due to external agents
0.834 0.166 0.000
W50-W64 Exposure to animate mechanical forces
0.834 0.166 0.000
Z40 Prophylactic surgery
0.832 0.168 0.000
E10 Insulin-dependent diabetes mellitus
0.832 0.168 0.000
J18 Pneumonia, organism unspecified
0.831 0.169 0.000
S43.0 Dislocation of shoulder joint
0.831 0.169 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.827 0.173 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.825 0.175 0.000
J18.9 Pneumonia, unspecified
0.823 0.177 0.000
N18.5 Chronic kidney disease, stage 5
0.820 0.180 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.818 0.182 0.000
S40 Superficial injury of shoulder and upper arm
0.817 0.183 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.817 0.183 0.000
N05 Unspecified nephritic syndrome
0.817 0.183 0.000
Z52 Donors of organs and tissues
0.816 0.184 0.000
E83.4 Disorders of magnesium metabolism
0.810 0.190 0.000
Z49.0 Preparatory care for dialysis
0.810 0.190 0.000
Y52 Agents primarily affecting the cardiovascular system
0.806 0.194 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.805 0.195 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.804 0.196 0.000
O47 False labour
0.803 0.197 0.000
J02 Acute pharyngitis
0.802 0.198 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.800 0.200 0.000
N03 Chronic nephritic syndrome
0.800 0.200 0.000
J06.9 Acute upper respiratory infection, unspecified
0.799 0.201 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.798 0.202 0.000
Y45.2 Propionic acid derivatives
0.798 0.202 0.000
H93.1 Tinnitus
0.796 0.204 0.000
O42 Premature rupture of membranes
0.795 0.205 0.000
N17 Acute renal failure
0.794 0.206 0.000
E21.0 Primary hyperparathyroidism
0.792 0.208 0.000
O63.0 Prolonged first stage (of labour)
0.787 0.213 0.000
V20-V29 Motorcycle rider injured in transport accident
0.787 0.213 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.785 0.215 0.000
B25-B34 Other viral diseases
0.785 0.215 0.000
V40-V49 Car occupant injured in transport accident
0.782 0.218 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.780 0.220 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.778 0.222 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.777 0.223 0.000
O80 Single spontaneous delivery
0.777 0.223 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.775 0.225 0.000
N76 Other inflammation of vagina and vulva
0.774 0.226 0.000
Z31 Procreative management
0.774 0.226 0.000
V98-V99 Other and unspecified transport accidents
0.771 0.229 0.000
O36.5 Maternal care for poor foetal growth
0.771 0.229 0.000
O75.0 Maternal distress during labour and delivery
0.770 0.230 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.769 0.231 0.000
N71 Inflammatory disease of uterus, except cervix
0.768 0.232 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.767 0.233 0.000
Chapter XI Diseases of the digestive system
0.767 0.233 0.000
O72.0 Third-stage haemorrhage
0.764 0.236 0.000
Q60-Q64 Congenital malformations of the urinary system
0.764 0.236 0.000
Z50 Care involving use of rehabilitation procedures
0.761 0.239 0.000
Y44 Agents primarily affecting blood constituents
0.761 0.239 0.000
X20-X29 Contact with venomous animals and plants
0.760 0.240 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.759 0.241 0.000
E40-E46 Malnutrition
0.759 0.241 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.757 0.243 0.000
E04.9 Non-toxic goitre, unspecified
0.754 0.246 0.000
T87 Complications peculiar to reattachment and amputation
0.752 0.248 0.000
H92 Otalgia and effusion of ear
0.752 0.248 0.000
O90 Complications of the puerperium, not elsewhere classified
0.751 0.248 0.000
B35-B49 Mycoses
0.751 0.249 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.751 0.249 0.000
K55-K64 Other diseases of intestines
0.750 0.250 0.000
Y00-Y09 Assault
0.750 0.250 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.749 0.251 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.748 0.252 0.000
N18.8 Other chronic renal failure
0.748 0.252 0.000
K61 Abscess of anal and rectal regions
0.748 0.252 0.000
O75.8 Other specified complications of labour and delivery
0.746 0.254 0.000
O66 Other obstructed labour
0.746 0.254 0.000
J01 Acute sinusitis
0.746 0.254 0.000
H61 Other disorders of external ear
0.746 0.254 0.000
Chapter VI Diseases of the nervous system
0.745 0.255 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
A49 Bacterial infection of unspecified site
0.745 0.255 0.000
K61.0 Anal abscess
0.745 0.255 0.000
E10.1 With ketoacidosis
0.744 0.256 0.000
K60 Fissure and fistula of anal and rectal regions
0.743 0.257 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.743 0.257 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.740 0.260 0.000
H60 Otitis externa
0.739 0.261 0.000
K70-K77 Diseases of liver
0.737 0.263 0.000
N18.4 Chronic kidney disease, stage 4
0.735 0.265 0.000
J02.9 Acute pharyngitis, unspecified
0.735 0.265 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.735 0.265 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.730 0.270 0.000
E28 Ovarian dysfunction
0.729 0.271 0.000
A80-A89 Viral infections of the central nervous system
0.729 0.271 0.000
O71 Other obstetric trauma
0.729 0.271 0.000
E50-E64 Other nutritional deficiencies
0.729 0.271 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.728 0.272 0.000
E73 Lactose intolerance
0.728 0.272 0.000
Z49.2 Other dialysis
0.728 0.272 0.000
H90 Conductive and sensorineural hearing loss
0.728 0.272 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.727 0.273 0.000
N04 Nephrotic syndrome
0.727 0.273 0.000
N99-N99 Other disorders of the genitourinary system
0.727 0.273 0.000
E20 Hypoparathyroidism
0.726 0.273 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.726 0.274 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.725 0.275 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.725 0.275 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.724 0.276 0.000
O40 Polyhydramnios
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.276 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.723 0.277 0.000
K60.1 Chronic anal fissure
0.721 0.279 0.000
E88 Other metabolic disorders
0.721 0.279 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.721 0.279 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.721 0.279 0.000
Q50-Q56 Congenital malformations of genital organs
0.721 0.279 0.000
K60.3 Anal fistula
0.719 0.281 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.718 0.282 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
O62 Abnormalities of forces of labour
0.716 0.284 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.716 0.284 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
Z46 Fitting and adjustment of other devices
0.711 0.289 0.000
Z39 Postpartum care and examination
0.711 0.289 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.711 0.289 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.710 0.290 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.709 0.291 0.000
O86 Other puerperal infections
0.709 0.291 0.000
E10.3 With ophthalmic complications
0.709 0.291 0.000
T88.5 Other complications of anaesthesia
0.708 0.292 0.000
H61.2 Impacted cerumen
0.708 0.292 0.000
T88.4 Failed or difficult intubation
0.707 0.292 0.000
Z54 Convalescence
0.707 0.293 0.000
A40 Streptococcal septicaemia
0.706 0.293 0.000
N03.9 Unspecified
0.706 0.294 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.706 0.294 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.704 0.296 0.000
O82.1 Delivery by emergency Caesarean section
0.703 0.297 0.000
S42.1 Fracture of scapula
0.703 0.297 0.000
J69 Pneumonitis due to solids and liquids
0.702 0.298 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.298 0.000
S20-S29 Injuries to the thorax
0.702 0.298 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.700 0.300 0.000
S48 Traumatic amputation of shoulder and upper arm
0.698 0.301 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.698 0.301 0.000
S44 Injury of nerves at shoulder and upper arm level
0.698 0.301 0.000
S47 Crushing injury of shoulder and upper arm
0.698 0.301 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.698 0.302 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.697 0.303 0.000
E04.1 Non-toxic single thyroid nodule
0.697 0.303 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.697 0.303 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.697 0.303 0.000
O72.3 Postpartum coagulation defects
0.697 0.303 0.000
E24 Cushing's syndrome
0.696 0.304 0.000
B25 Cytomegaloviral disease
0.696 0.304 0.000
V18.0 Driver injured in nontraffic accident
0.694 0.306 0.000
K90-K93 Other diseases of the digestive system
0.694 0.306 0.000
E85 Amyloidosis
0.692 0.308 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.691 0.309 0.000
N18.0 End-stage renal disease
0.691 0.309 0.000
E13 Other specified diabetes mellitus
0.690 0.310 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.690 0.310 0.000
E26 Hyperaldosteronism
0.690 0.310 0.000
E27.1 Primary adrenocortical insufficiency
0.690 0.310 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.689 0.311 0.000
S41 Open wound of shoulder and upper arm
0.689 0.311 0.000
N05.2 Diffuse membranous glomerulonephritis
0.689 0.311 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.688 0.312 0.000
Y59 Other and unspecified vaccines and biological substances
0.688 0.312 0.000
Y58 Bacterial vaccines
0.688 0.312 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.688 0.312 0.000
Y48 Anaesthetics and therapeutic gases
0.688 0.312 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.688 0.312 0.000
O44 Placenta praevia
0.686 0.313 0.000
O81 Single delivery by forceps and vacuum extractor
0.685 0.315 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.684 0.315 0.000
O84 Multiple delivery
0.684 0.316 0.000
O83 Other assisted single delivery
0.684 0.316 0.000
J95-J99 Other diseases of the respiratory system
0.684 0.316 0.000
Z33 Pregnant state, incidental
0.684 0.316 0.000
B15-B19 Viral hepatitis
0.683 0.316 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.317 0.000
E34 Other endocrine disorders
0.683 0.317 0.000
E32 Diseases of thymus
0.683 0.317 0.000
E31 Polyglandular dysfunction
0.683 0.317 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.317 0.000
E25 Adrenogenital disorders
0.683 0.317 0.000
O36.6 Maternal care for excessive foetal growth
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
O43 Placental disorders
0.683 0.317 0.000
O33 Maternal care for known or suspected disproportion
0.682 0.318 0.000
O31 Complications specific to multiple gestation
0.682 0.318 0.000
Y65 Other misadventures during surgical and medical care
0.682 0.318 0.000
N76.8 Other specified inflammation of vagina and vulva
0.682 0.318 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.681 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.681 0.319 0.000
O80.0 Spontaneous vertex delivery
0.681 0.319 0.000
T21 Burn and corrosion of trunk
0.681 0.319 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.320 0.000
O34.3 Maternal care for cervical incompetence
0.680 0.320 0.000
N17.9 Acute renal failure, unspecified
0.679 0.321 0.000
Z37.1 Single stillbirth
0.678 0.321 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.322 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.678 0.322 0.000
H65-H75 Diseases of middle ear and mastoid
0.678 0.322 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.677 0.323 0.000
O47.9 False labour, unspecified
0.677 0.323 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.677 0.323 0.000
Z44 Fitting and adjustment of external prosthetic device
0.676 0.323 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.675 0.325 0.000
N75.8 Other diseases of Bartholin's gland
0.675 0.325 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.672 0.328 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.671 0.329 0.000
X50-X57 Overexertion, travel and privation
0.670 0.330 0.000
E87.4 Mixed disorder of acid-base balance
0.669 0.331 0.000
E10.9 Without complications
0.669 0.331 0.000
Y83.4 Other reconstructive surgery
0.667 0.333 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.667 0.333 0.000
N06 Isolated proteinuria with specified morphological lesion
0.667 0.333 0.000
N01 Rapidly progressive nephritic syndrome
0.667 0.333 0.000
N00 Acute nephritic syndrome
0.667 0.333 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.667 0.333 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.667 0.333 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.666 0.334 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.666 0.334 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.666 0.334 0.000
E27.8 Other specified disorders of adrenal gland
0.664 0.335 0.000
Y45.1 Salicylates
0.664 0.336 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.663 0.337 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.662 0.338 0.000
Y45.8 Other analgesics and antipyretics
0.662 0.338 0.000
Y45.5 4-Aminophenol derivatives
0.662 0.338 0.000
Y45.4 Antirheumatics
0.662 0.338 0.000
E03 Other hypothyroidism
0.662 0.338 0.000
T31 Burns classified according to extent of body surface involved
0.662 0.338 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.661 0.338 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.661 0.339 0.000
E00 Congenital iodine-deficiency syndrome
0.661 0.339 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.661 0.339 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.660 0.340 0.000
J20-J22 Other acute lower respiratory infections
0.660 0.340 0.000
Z52.4 Kidney donor
0.660 0.340 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.659 0.341 0.000
B50-B64 Protozoal diseases
0.659 0.341 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.659 0.341 0.000
A75-A79 Rickettsioses
0.659 0.341 0.000
A70-A74 Other diseases caused by chlamydiae
0.659 0.341 0.000
A65-A69 Other spirochaetal diseases
0.659 0.341 0.000
A20-A28 Certain zoonotic bacterial diseases
0.659 0.341 0.000
A15-A19 Tuberculosis
0.659 0.341 0.000
J11 Influenza, virus not identified
0.658 0.342 0.000
O75.9 Complication of labour and delivery, unspecified
0.657 0.343 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.657 0.343 0.000
O75.4 Other complications of obstetric surgery and procedures
0.657 0.343 0.000
O75.3 Other infection during labour
0.657 0.343 0.000
O75.1 Shock during or following labour and delivery
0.657 0.343 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.657 0.343 0.000
B95-B98 Bacterial, viral and other infectious agents
0.657 0.343 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.657 0.343 0.000
E06 Thyroiditis
0.656 0.344 0.000
T81.9 Unspecified complication of procedure
0.656 0.344 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.655 0.345 0.000
O36.2 Maternal care for hydrops foetalis
0.655 0.345 0.000
O36.1 Maternal care for other isoimmunisation
0.655 0.345 0.000
N18.1 Chronic kidney disease, stage 1
0.655 0.345 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
E29 Testicular dysfunction
0.654 0.346 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.653 0.347 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.653 0.347 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.653 0.347 0.000
S42.21 Fracture of upper end of humerus (open)
0.652 0.348 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.652 0.348 0.000
H91 Other hearing loss
0.652 0.348 0.000
O82.9 Delivery by Caesarean section, unspecified
0.651 0.349 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
J18.8 Other pneumonia, organism unspecified
0.649 0.351 0.000
H60.9 Otitis externa, unspecified
0.649 0.351 0.000
A49.0 Staphylococcal infection, unspecified
0.649 0.351 0.000
O61 Failed induction of labour
0.648 0.352 0.000
E27.9 Disorder of adrenal gland, unspecified
0.648 0.352 0.000
H90.5 Sensorineural hearing loss, unspecified
0.648 0.352 0.000
O82.8 Other single delivery by Caesarean section
0.648 0.352 0.000
O82.2 Delivery by Caesarean hysterectomy
0.648 0.352 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.647 0.353 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.647 0.353 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.647 0.353 0.000
E89.5 Postprocedural testicular hypofunction
0.647 0.353 0.000
E89.4 Postprocedural ovarian failure
0.647 0.353 0.000
E89.3 Postprocedural hypopituitarism
0.647 0.353 0.000
E89.1 Postprocedural hypoinsulinaemia
0.647 0.353 0.000
A39 Meningococcal infection
0.646 0.354 0.000
O63.9 Long labour, unspecified
0.645 0.355 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.645 0.355 0.000
K72 Hepatic failure, not elsewhere classified
0.645 0.355 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.644 0.356 0.000
Z52.3 Bone marrow donor
0.644 0.356 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.643 0.357 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.643 0.357 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.642 0.357 0.000
E10.2 With renal complications
0.641 0.359 0.000
S10-S19 Injuries to the neck
0.641 0.359 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.640 0.360 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.640 0.360 0.000
Z50.5 Speech therapy
0.640 0.360 0.000
J01.9 Acute sinusitis, unspecified
0.640 0.360 0.000
E04.2 Non-toxic multinodular goitre
0.640 0.360 0.000
O36.4 Maternal care for intra-uterine death
0.639 0.361 0.000
Y49.2 Other and unspecified antidepressants
0.639 0.361 0.000
J17 Pneumonia in diseases classified elsewhere
0.638 0.362 0.000
W55 Bitten or struck by other mammals
0.638 0.362 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.638 0.362 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.637 0.362 0.000
E86 Volume depletion
0.637 0.363 0.000
E04.0 Non-toxic diffuse goitre
0.637 0.363 0.000
K92 Other diseases of digestive system
0.637 0.363 0.000
T23 Burn and corrosion of wrist and hand
0.636 0.364 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.636 0.364 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.636 0.364 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.636 0.364 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.636 0.364 0.000
S43.4 Sprain and strain of shoulder joint
0.636 0.364 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.636 0.364 0.000
S43.2 Dislocation of sternoclavicular joint
0.636 0.364 0.000
K75 Other inflammatory liver diseases
0.636 0.364 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.635 0.364 0.000
S42.3 Fracture of shaft of humerus
0.635 0.365 0.000
N05.9 Unspecified
0.635 0.365 0.000
Z32 Pregnancy examination and test
0.635 0.365 0.000
Z52.8 Donor of other organs and tissues
0.634 0.365 0.000
O73 Retained placenta and membranes, without haemorrhage
0.634 0.366 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.633 0.367 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.632 0.367 0.000
Z45.3 Adjustment and management of implanted hearing device
0.632 0.367 0.000
A49.8 Other bacterial infections of unspecified site
0.632 0.368 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.632 0.368 0.000
B25.9 Cytomegaloviral disease, unspecified
0.632 0.368 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.632 0.368 0.000
K55 Vascular disorders of intestine
0.631 0.369 0.000
W51 Striking against or bumped into by another person
0.631 0.369 0.000
Y83.3 Surgical operation with formation of external stoma
0.630 0.370 0.000
N05.8 Other
0.630 0.370 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.630 0.370 0.000
O91 Infections of breast associated with childbirth
0.630 0.370 0.000
O89 Complications of anaesthesia during the puerperium
0.630 0.370 0.000
O88 Obstetric embolism
0.630 0.370 0.000
O87 Venous complications in the puerperium
0.630 0.370 0.000
O85 Puerperal sepsis
0.630 0.370 0.000
Y42.7 Androgens and anabolic congeners
0.630 0.370 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.629 0.371 0.000
H92.1 Otorrhoea
0.629 0.371 0.000
E23 Hypofunction and other disorders of pituitary gland
0.629 0.371 0.000
K70 Alcoholic liver disease
0.629 0.371 0.000
Z38 Liveborn infants according to place of birth
0.628 0.372 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.627 0.373 0.000
Z45.1 Adjustment and management of infusion pump
0.627 0.373 0.000
T66-T78 Other and unspecified effects of external causes
0.626 0.374 0.000
E12 Malnutrition-related diabetes mellitus
0.626 0.374 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.625 0.375 0.000
K92.1 Melaena
0.624 0.376 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.624 0.376 0.000
Q00-Q07 Congenital malformations of the nervous system
0.624 0.376 0.000
B99-B99 Other infectious diseases
0.624 0.376 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.623 0.377 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.622 0.377 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.621 0.379 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.621 0.379 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.621 0.379 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.621 0.379 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.621 0.379 0.000
Z37.9 Outcome of delivery unspecified
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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