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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7307889
log Bayes Factor = 7.08994
Chromosome 12   position 5,981,353  (GRCh37) Explore rs7307889 on Ensembl!
Variant rs7307889 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
E86 Volume depletion
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Chapter XIV Diseases of the genitourinary system
0.992 0.008 0.000
H65-H75 Diseases of middle ear and mastoid
0.992 0.008 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.991 0.009 0.000
C44 Other malignant neoplasms of skin
0.984 0.016 0.000
E10-E14 Diabetes mellitus
0.983 0.017 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.978 0.022 0.000
Chapter I Certain infectious and parasitic diseases
0.970 0.030 0.000
N17-N19 Renal failure
0.962 0.038 0.000
H90-H95 Other disorders of ear
0.961 0.039 0.000
E10 Insulin-dependent diabetes mellitus
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.955 0.045 0.000
N40-N51 Diseases of male genital organs
0.950 0.050 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.947 0.053 0.000
H66 Suppurative and unspecified otitis media
0.945 0.055 0.000
C44.5 Skin of trunk
0.940 0.060 0.000
C44.6 Skin of upper limb, including shoulder
0.937 0.063 0.000
N17 Acute renal failure
0.937 0.063 0.000
C60-C63 Malignant neoplasms of male genital organs
0.935 0.065 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.915 0.085 0.000
H91 Other hearing loss
0.910 0.090 0.000
A00-A09 Intestinal infectious diseases
0.909 0.091 0.000
N17.9 Acute renal failure, unspecified
0.906 0.094 0.000
H65 Nonsuppurative otitis media
0.905 0.095 0.000
N40 Hyperplasia of prostate
0.904 0.096 0.000
N60-N64 Disorders of breast
0.888 0.112 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.884 0.116 0.000
C61 Malignant neoplasm of prostate
0.883 0.117 0.000
N20-N23 Urolithiasis
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.882 0.118 0.000
H91.9 Hearing loss, unspecified
0.875 0.125 0.000
C44.4 Skin of scalp and neck
0.868 0.132 0.000
M80-M85 Disorders of bone density and structure
0.866 0.134 0.000
N21 Calculus of lower urinary tract
0.864 0.136 0.000
S20-S29 Injuries to the thorax
0.861 0.139 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.861 0.139 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.861 0.139 0.000
H90 Conductive and sensorineural hearing loss
0.859 0.141 0.000
E10.9 Without complications
0.858 0.142 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.858 0.142 0.000
S00-S09 Injuries to the head
0.856 0.144 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.855 0.145 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.853 0.147 0.000
H66.3 Other chronic suppurative otitis media
0.851 0.149 0.000
N21.0 Calculus in bladder
0.851 0.149 0.000
M86-M90 Other osteopathies
0.849 0.151 0.000
H66.9 Otitis media, unspecified
0.849 0.151 0.000
H72 Perforation of tympanic membrane
0.847 0.153 0.000
N61 Inflammatory disorders of breast
0.843 0.157 0.000
C51-C58 Malignant neoplasms of female genital organs
0.842 0.158 0.000
B25-B34 Other viral diseases
0.840 0.159 0.000
M05-M14 Inflammatory polyarthropathies
0.836 0.164 0.000
S60-S69 Injuries to the wrist and hand
0.836 0.164 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.834 0.166 0.000
D00-D09 In situ neoplasms
0.831 0.169 0.000
E87.7 Fluid overload
0.829 0.171 0.000
N41 Inflammatory diseases of prostate
0.825 0.175 0.000
H74 Other disorders of middle ear and mastoid
0.823 0.177 0.000
N18 Chronic renal failure
0.822 0.178 0.000
M50-M54 Other dorsopathies
0.812 0.188 0.000
C64-C68 Malignant neoplasms of urinary tract
0.810 0.190 0.000
E10.8 With unspecified complications
0.809 0.191 0.000
N00-N08 Glomerular diseases
0.808 0.192 0.000
E10.3 With ophthalmic complications
0.804 0.196 0.000
H73 Other disorders of tympanic membrane
0.802 0.198 0.000
C43 Malignant melanoma of skin
0.800 0.200 0.000
N63 Unspecified lump in breast
0.800 0.200 0.000
M06 Other rheumatoid arthritis
0.799 0.201 0.000
M80 Osteoporosis with pathological fracture
0.799 0.201 0.000
S50-S59 Injuries to the elbow and forearm
0.796 0.204 0.000
E83 Disorders of mineral metabolism
0.796 0.204 0.000
Y95 Nosocomial condition
0.794 0.206 0.000
N48 Other disorders of penis
0.794 0.206 0.000
C53 Malignant neoplasm of cervix uteri
0.794 0.206 0.000
E13 Other specified diabetes mellitus
0.794 0.206 0.000
E10.2 With renal complications
0.791 0.209 0.000
E11 Non-insulin-dependent diabetes mellitus
0.791 0.209 0.000
H90.2 Conductive hearing loss, unspecified
0.790 0.210 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.789 0.211 0.000
M45-M49 Spondylopathies
0.787 0.213 0.000
L20-L30 Dermatitis and eczema
0.786 0.214 0.000
S01 Open wound of head
0.784 0.216 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.783 0.217 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.782 0.218 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
A30-A49 Other bacterial diseases
0.781 0.219 0.000
M54 Dorsalgia
0.781 0.219 0.000
N17.0 Acute renal failure with tubular necrosis
0.778 0.222 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.776 0.224 0.000
E87.5 Hyperkalaemia
0.776 0.224 0.000
S70-S79 Injuries to the hip and thigh
0.775 0.225 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.772 0.228 0.000
N25-N29 Other disorders of kidney and ureter
0.768 0.231 0.000
S62 Fracture at wrist and hand level
0.766 0.234 0.000
H65.4 Other chronic nonsuppurative otitis media
0.764 0.236 0.000
M06.9 Rheumatoid arthritis, unspecified
0.764 0.236 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.764 0.236 0.000
H65.3 Chronic mucoid otitis media
0.764 0.236 0.000
B95-B98 Bacterial, viral and other infectious agents
0.763 0.237 0.000
C44.2 Skin of ear and external auricular canal
0.762 0.238 0.000
H60-H62 Diseases of external ear
0.761 0.239 0.000
B35-B49 Mycoses
0.759 0.241 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
E87.0 Hyperosmolality and hypernatraemia
0.753 0.247 0.000
E87.2 Acidosis
0.751 0.249 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.748 0.252 0.000
B34 Viral infection of unspecified site
0.748 0.252 0.000
S20 Superficial injury of thorax
0.747 0.253 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.745 0.255 0.000
E40-E46 Malnutrition
0.744 0.256 0.000
N41.1 Chronic prostatitis
0.744 0.256 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.743 0.256 0.000
T79-T79 Certain early complications of trauma
0.743 0.257 0.000
L08 Other local infections of skin and subcutaneous tissue
0.738 0.262 0.000
T92 Sequelae of injuries of upper limb
0.736 0.264 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.736 0.264 0.000
M54.1 Radiculopathy
0.734 0.266 0.000
S40-S49 Injuries to the shoulder and upper arm
0.733 0.267 0.000
C44.0 Skin of lip
0.732 0.268 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.730 0.270 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.729 0.271 0.000
C53.9 Cervix uteri, unspecified
0.729 0.271 0.000
S01.8 Open wound of other parts of head
0.727 0.273 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.726 0.274 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.724 0.276 0.000
M88 Paget's disease of bone [osteitis deformans]
0.723 0.277 0.000
E87.6 Hypokalaemia
0.721 0.279 0.000
Y40 Systemic antibiotics
0.720 0.280 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
S67 Crushing injury of wrist and hand
0.715 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.713 0.287 0.000
E10.5 With peripheral circulatory complications
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.711 0.289 0.000
H70 Mastoiditis and related conditions
0.711 0.289 0.000
H68 Eustachian salpingitis and obstruction
0.711 0.289 0.000
H67 Otitis media in diseases classified elsewhere
0.711 0.289 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.709 0.291 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.709 0.291 0.000
E10.4 With neurological complications
0.709 0.291 0.000
H69 Other disorders of Eustachian tube
0.708 0.292 0.000
E87.3 Alkalosis
0.708 0.292 0.000
N42 Other disorders of prostate
0.707 0.293 0.000
C62 Malignant neoplasm of testis
0.706 0.294 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.705 0.294 0.000
C44.8 Overlapping lesion of skin
0.705 0.294 0.000
E12 Malnutrition-related diabetes mellitus
0.705 0.295 0.000
M54.5 Low back pain
0.704 0.296 0.000
M89 Other disorders of bone
0.702 0.298 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.702 0.298 0.000
E87.4 Mixed disorder of acid-base balance
0.701 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
M85 Other disorders of bone density and structure
0.701 0.299 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.698 0.301 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.698 0.302 0.000
M54.16 Radiculopathy (Lumbar region)
0.697 0.303 0.000
C15-C26 Malignant neoplasms of digestive organs
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.695 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.304 0.000
B65-B83 Helminthiases
0.695 0.304 0.000
B50-B64 Protozoal diseases
0.695 0.304 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.304 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.304 0.000
A75-A79 Rickettsioses
0.695 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.304 0.000
A65-A69 Other spirochaetal diseases
0.695 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.304 0.000
A15-A19 Tuberculosis
0.695 0.304 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.693 0.307 0.000
D03 Melanoma in situ
0.692 0.308 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.692 0.308 0.000
B15-B19 Viral hepatitis
0.690 0.309 0.000
E65-E68 Obesity and other hyperalimentation
0.690 0.310 0.000
M54.56 Low back pain (Lumbar region)
0.689 0.311 0.000
A08 Viral and other specified intestinal infections
0.689 0.311 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.689 0.311 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.689 0.311 0.000
E10.7 With multiple complications
0.688 0.312 0.000
E10.6 With other specified complications
0.688 0.312 0.000
E10.0 With coma
0.688 0.312 0.000
A02 Other Salmonella infections
0.686 0.314 0.000
L03 Cellulitis
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
W50-W64 Exposure to animate mechanical forces
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
E10.1 With ketoacidosis
0.684 0.316 0.000
D06 Carcinoma in situ of cervix uteri
0.684 0.316 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.684 0.316 0.000
Q50-Q56 Congenital malformations of genital organs
0.683 0.317 0.000
N18.3 Chronic kidney disease, stage 3
0.682 0.318 0.000
T93 Sequelae of injuries of lower limb
0.682 0.318 0.000
S62.3 Fracture of other metacarpal bone
0.681 0.318 0.000
E50-E64 Other nutritional deficiencies
0.681 0.319 0.000
B34.9 Viral infection, unspecified
0.681 0.319 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.681 0.319 0.000
N46 Male infertility
0.681 0.319 0.000
N44 Torsion of testis
0.681 0.319 0.000
M60-M63 Disorders of muscles
0.679 0.321 0.000
M00-M03 Infectious arthropathies
0.679 0.321 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.321 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.678 0.322 0.000
H66.4 Suppurative otitis media, unspecified
0.677 0.323 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.677 0.323 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.677 0.323 0.000
H66.0 Acute suppurative otitis media
0.677 0.323 0.000
N99-N99 Other disorders of the genitourinary system
0.677 0.323 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.677 0.323 0.000
L30 Other dermatitis
0.677 0.323 0.000
M91-M94 Chondropathies
0.676 0.324 0.000
E14 Unspecified diabetes mellitus
0.676 0.324 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
C53.0 Endocervix
0.674 0.326 0.000
N50 Other disorders of male genital organs
0.673 0.327 0.000
N17.8 Other acute renal failure
0.671 0.328 0.000
N17.2 Acute renal failure with medullary necrosis
0.671 0.328 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.671 0.328 0.000
H72.8 Other perforations of tympanic membrane
0.671 0.329 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.670 0.330 0.000
C60 Malignant neoplasm of penis
0.670 0.330 0.000
E11.5 With peripheral circulatory complications
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.670 0.330 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.670 0.330 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
N18.2 Chronic kidney disease, stage 2
0.667 0.333 0.000
H73.8 Other specified disorders of tympanic membrane
0.667 0.333 0.000
C44.7 Skin of lower limb, including hip
0.665 0.335 0.000
S06 Intracranial injury
0.665 0.335 0.000
T66-T78 Other and unspecified effects of external causes
0.663 0.337 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.660 0.340 0.000
M07 Psoriatic and enteropathic arthropathies
0.660 0.340 0.000
C43.9 Malignant melanoma of skin, unspecified
0.660 0.340 0.000
E13.9 Without complications
0.658 0.342 0.000
L50-L54 Urticaria and erythema
0.658 0.342 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.657 0.343 0.000
A49 Bacterial infection of unspecified site
0.657 0.343 0.000
W00-W19 Falls
0.655 0.345 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.654 0.346 0.000
M48 Other spondylopathies
0.653 0.347 0.000
H91.8 Other specified hearing loss
0.653 0.347 0.000
H91.3 Deaf mutism, not elsewhere classified
0.653 0.347 0.000
H91.2 Sudden idiopathic hearing loss
0.653 0.347 0.000
H91.1 Presbycusis
0.653 0.347 0.000
H91.0 Ototoxic hearing loss
0.653 0.347 0.000
N18.4 Chronic kidney disease, stage 4
0.653 0.347 0.000
A07 Other protozoal intestinal diseases
0.652 0.348 0.000
A06 Amoebiasis
0.652 0.348 0.000
A05 Other bacterial foodborne intoxications
0.652 0.348 0.000
A03 Shigellosis
0.652 0.348 0.000
A01 Typhoid and paratyphoid fevers
0.652 0.348 0.000
A00 Cholera
0.652 0.348 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.652 0.348 0.000
M05 Seropositive rheumatoid arthritis
0.651 0.349 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.651 0.349 0.000
S90-S99 Injuries to the ankle and foot
0.650 0.349 0.000
N18.5 Chronic kidney disease, stage 5
0.650 0.350 0.000
L29 Pruritus
0.650 0.350 0.000
H65.2 Chronic serous otitis media
0.649 0.351 0.000
H65.1 Other acute nonsuppurative otitis media
0.649 0.351 0.000
H65.0 Acute serous otitis media
0.649 0.351 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.649 0.351 0.000
M70-M79 Other soft tissue disorders
0.648 0.352 0.000
S62.6 Fracture of other finger
0.646 0.353 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.646 0.354 0.000
E00-E07 Disorders of thyroid gland
0.646 0.354 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.646 0.354 0.000
N48.6 Balanitis xerotica obliterans
0.644 0.356 0.000
E11.4 With neurological complications
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.642 0.358 0.000
M90 Osteopathies in diseases classified elsewhere
0.641 0.359 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.640 0.359 0.000
Y57 Other and unspecified drugs and medicaments
0.641 0.359 0.000
H72.0 Central perforation of tympanic membrane
0.640 0.360 0.000
H93 Other disorders of ear, not elsewhere classified
0.638 0.362 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.638 0.362 0.000
T91 Sequelae of injuries of neck and trunk
0.635 0.365 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.634 0.365 0.000
S29 Other and unspecified injuries of thorax
0.634 0.366 0.000
E83.4 Disorders of magnesium metabolism
0.634 0.366 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.634 0.366 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.633 0.366 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.633 0.367 0.000
M88.9 Paget's disease of bone, unspecified
0.633 0.367 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.633 0.367 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.632 0.368 0.000
Q80-Q89 Other congenital malformations
0.632 0.368 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.632 0.368 0.000
Q35-Q37 Cleft lip and cleft palate
0.632 0.368 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.632 0.368 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.632 0.368 0.000
M47 Spondylosis
0.632 0.368 0.000
N48.8 Other specified disorders of penis
0.632 0.368 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.632 0.368 0.000
M86 Osteomyelitis
0.631 0.369 0.000
H92 Otalgia and effusion of ear
0.631 0.369 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.631 0.369 0.000
S27 Injury of other and unspecified intrathoracic organs
0.630 0.370 0.000
E11.2 With renal complications
0.630 0.370 0.000
N48.2 Other inflammatory disorders of penis
0.629 0.371 0.000
S51 Open wound of forearm
0.629 0.371 0.000
T63 Toxic effect of contact with venomous animals
0.629 0.371 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.628 0.372 0.000
S01.2 Open wound of nose
0.628 0.372 0.000
C51 Malignant neoplasm of vulva
0.628 0.372 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.627 0.373 0.000
M06.0 Seronegative rheumatoid arthritis
0.626 0.374 0.000
M54.3 Sciatica
0.624 0.376 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.624 0.376 0.000
E88 Other metabolic disorders
0.623 0.377 0.000
S64 Injury of nerves at wrist and hand level
0.622 0.378 0.000
Y40.8 Other systemic antibiotics
0.622 0.378 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.622 0.378 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.622 0.378 0.000
M83 Adult osteomalacia
0.621 0.379 0.000
M82 Osteoporosis in diseases classified elsewhere
0.621 0.379 0.000
T23 Burn and corrosion of wrist and hand
0.621 0.379 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.621 0.379 0.000
S50 Superficial injury of forearm
0.620 0.379 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.620 0.380 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.620 0.380 0.000
D48.7 Other specified sites
0.620 0.380 0.000
Y44 Agents primarily affecting blood constituents
0.619 0.380 0.000
X78 Intentional self-harm by sharp object
0.619 0.381 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.619 0.381 0.000
N21.8 Other lower urinary tract calculus
0.619 0.381 0.000
N21.1 Calculus in urethra
0.619 0.381 0.000
C44.1 Skin of eyelid, including canthus
0.618 0.382 0.000
Chapter X Diseases of the respiratory system
0.618 0.382 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.618 0.382 0.000
Q00-Q07 Congenital malformations of the nervous system
0.618 0.382 0.000
S20.2 Contusion of thorax
0.618 0.382 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.617 0.382 0.000
S26 Injury of heart
0.617 0.382 0.000
S25 Injury of blood vessels of thorax
0.617 0.382 0.000
S24 Injury of nerves and spinal cord at thorax level
0.617 0.382 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.617 0.382 0.000
S21 Open wound of thorax
0.617 0.382 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.617 0.382 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.617 0.382 0.000
Y98 Lifestyle-related condition
0.617 0.382 0.000
Y97 Environmental-pollution-related condition
0.617 0.382 0.000
Y96 Work-related condition
0.617 0.382 0.000
T98 Sequelae of other and unspecified effects of external causes
0.617 0.383 0.000
T95 Sequelae of burns, corrosions and frostbite
0.617 0.383 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.617 0.383 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.617 0.383 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.617 0.383 0.000
C43.4 Malignant melanoma of scalp and neck
0.617 0.383 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.616 0.384 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.616 0.384 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.616 0.384 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.616 0.384 0.000
H90.3 Sensorineural hearing loss, bilateral
0.616 0.384 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.616 0.384 0.000
H90.0 Conductive hearing loss, bilateral
0.616 0.384 0.000
T86 Failure and rejection of transplanted organs and tissues
0.616 0.384 0.000
L10-L14 Bullous disorders
0.615 0.385 0.000
S00 Superficial injury of head
0.615 0.385 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.615 0.385 0.000
L27 Dermatitis due to substances taken internally
0.614 0.386 0.000
S08 Traumatic amputation of part of head
0.614 0.386 0.000
S07 Crushing injury of head
0.614 0.386 0.000
S05 Injury of eye and orbit
0.614 0.386 0.000
S04 Injury of cranial nerves
0.614 0.386 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.614 0.386 0.000
Y59 Other and unspecified vaccines and biological substances
0.613 0.387 0.000
Y58 Bacterial vaccines
0.613 0.387 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.613 0.387 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.613 0.387 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.613 0.387 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.613 0.387 0.000
Y52 Agents primarily affecting the cardiovascular system
0.613 0.387 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.613 0.387 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.613 0.387 0.000
Y48 Anaesthetics and therapeutic gases
0.613 0.387 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.613 0.387 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.613 0.387 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.613 0.387 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.613 0.387 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.613 0.387 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.613 0.387 0.000
S20.3 Other superficial injuries of front wall of thorax
0.613 0.387 0.000
C67 Malignant neoplasm of bladder
0.612 0.388 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.611 0.389 0.000
T82.1 Mechanical complication of cardiac electronic device
0.611 0.389 0.000
N45 Orchitis and epididymitis
0.609 0.391 0.000
H74.4 Polyp of middle ear
0.609 0.391 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.608 0.392 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.608 0.392 0.000
B37 Candidiasis
0.608 0.392 0.000
H72.2 Other marginal perforations of tympanic membrane
0.607 0.392 0.000
H72.1 Attic perforation of tympanic membrane
0.607 0.392 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.606 0.394 0.000
M54.2 Cervicalgia
0.605 0.395 0.000
S32 Fracture of lumbar spine and pelvis
0.604 0.396 0.000
S71 Open wound of hip and thigh
0.604 0.396 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.604 0.396 0.000
C58 Malignant neoplasm of placenta
0.604 0.396 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.604 0.396 0.000
C52 Malignant neoplasm of vagina
0.604 0.396 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.603 0.397 0.000
B33 Other viral diseases, not elsewhere classified
0.603 0.397 0.000
B30 Viral conjunctivitis
0.603 0.397 0.000
B27 Infectious mononucleosis
0.603 0.397 0.000
B26 Mumps
0.603 0.397 0.000
B25 Cytomegaloviral disease
0.603 0.397 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.602 0.398 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.602 0.398 0.000
S69 Other and unspecified injuries of wrist and hand
0.600 0.399 0.000
S72 Fracture of femur
0.601 0.399 0.000
N18.0 End-stage renal disease
0.600 0.400 0.000
E11.6 With other specified complications
0.600 0.400 0.000
M14 Arthropathies in other diseases classified elsewhere
0.599 0.400 0.000
M12 Other specific arthropathies
0.599 0.400 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.599 0.400 0.000
M08 Juvenile arthritis
0.599 0.400 0.000
S65 Injury of blood vessels at wrist and hand level
0.599 0.400 0.000
H90.5 Sensorineural hearing loss, unspecified
0.599 0.400 0.000
M40-M43 Deforming dorsopathies
0.599 0.401 0.000
T87 Complications peculiar to reattachment and amputation
0.598 0.402 0.000
S02 Fracture of skull and facial bones
0.597 0.403 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.596 0.404 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.596 0.404 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.596 0.404 0.000
S01.4 Open wound of cheek and temporomandibular area
0.594 0.406 0.000
J30-J39 Other diseases of upper respiratory tract
0.593 0.407 0.000
E11.3 With ophthalmic complications
0.593 0.407 0.000
Q24 Other congenital malformations of heart
0.593 0.407 0.000
X58 Exposure to other specified factors
0.592 0.408 0.000
N41.8 Other inflammatory diseases of prostate
0.592 0.408 0.000
N41.3 Prostatocystitis
0.592 0.408 0.000
N41.2 Abscess of prostate
0.592 0.408 0.000
N41.0 Acute prostatitis
0.592 0.408 0.000
D48.1 Connective and other soft tissue
0.592 0.408 0.000
N03 Chronic nephritic syndrome
0.591 0.408 0.000
E83.5 Disorders of calcium metabolism
0.591 0.409 0.000
N48.4 Impotence of organic origin
0.591 0.409 0.000
T90 Sequelae of injuries of head
0.590 0.410 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.590 0.410 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.590 0.410 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.590 0.410 0.000
H74.1 Adhesive middle ear disease
0.590 0.410 0.000
H74.0 Tympanosclerosis
0.590 0.410 0.000
N18.8 Other chronic renal failure
0.590 0.410 0.000
N18.1 Chronic kidney disease, stage 1
0.590 0.410 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.589 0.411 0.000
H60 Otitis externa
0.588 0.412 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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