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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73114523
log Bayes Factor = 14.6366
Chromosome 12   position 54,602,032  (GRCh37) Explore rs73114523 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
J09-J18 Influenza and pneumonia
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
J18 Pneumonia, organism unspecified
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
I25.2 Old myocardial infarction
0.982 0.018 0.000
M20-M25 Other joint disorders
0.979 0.021 0.000
J18.9 Pneumonia, unspecified
0.978 0.022 0.000
A00-A09 Intestinal infectious diseases
0.977 0.023 0.000
M20 Acquired deformities of fingers and toes
0.976 0.024 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.969 0.031 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.969 0.031 0.000
I60-I69 Cerebrovascular diseases
0.966 0.034 0.000
M20.1 Hallux valgus (acquired)
0.961 0.039 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.960 0.040 0.000
S09 Other and unspecified injuries of head
0.958 0.042 0.000
J95-J99 Other diseases of the respiratory system
0.958 0.042 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.957 0.043 0.000
I20 Angina pectoris
0.952 0.048 0.000
J18.1 Lobar pneumonia, unspecified
0.952 0.048 0.000
J90-J94 Other diseases of pleura
0.951 0.049 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.944 0.056 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.943 0.057 0.000
S09.9 Unspecified injury of head
0.940 0.060 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.937 0.063 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.933 0.067 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.932 0.068 0.000
I20.0 Unstable angina
0.932 0.068 0.000
S40-S49 Injuries to the shoulder and upper arm
0.929 0.071 0.000
J98 Other respiratory disorders
0.928 0.072 0.000
J90 Pleural effusion, not elsewhere classified
0.925 0.075 0.000
Y43 Primarily systemic agents
0.913 0.087 0.000
Z30 Contraceptive management
0.913 0.087 0.000
M70-M79 Other soft tissue disorders
0.910 0.090 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.910 0.090 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.907 0.093 0.000
I63 Cerebral infarction
0.907 0.093 0.000
J98.1 Pulmonary collapse
0.904 0.096 0.000
B95-B98 Bacterial, viral and other infectious agents
0.904 0.096 0.000
I30-I52 Other forms of heart disease
0.903 0.097 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.899 0.101 0.000
R06 Abnormalities of breathing
0.899 0.101 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.896 0.104 0.000
Z36 Antenatal screening
0.894 0.106 0.000
M45-M49 Spondylopathies
0.894 0.106 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.890 0.110 0.000
B25-B34 Other viral diseases
0.890 0.110 0.000
Y43.3 Other antineoplastic drugs
0.873 0.127 0.000
W00-W19 Falls
0.871 0.129 0.000
S00 Superficial injury of head
0.869 0.131 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.868 0.132 0.000
M20.5 Other deformities of toe(s) (acquired)
0.866 0.134 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.861 0.139 0.000
I69 Sequelae of cerebrovascular disease
0.858 0.142 0.000
R30-R39 Symptoms and signs involving the urinary system
0.851 0.149 0.000
R47-R49 Symptoms and signs involving speech and voice
0.850 0.150 0.000
I31 Other diseases of pericardium
0.849 0.151 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.848 0.152 0.000
R05 Cough
0.841 0.159 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.833 0.167 0.000
Z75 Problems related to medical facilities and other health care
0.833 0.167 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.831 0.169 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.830 0.170 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.828 0.172 0.000
R40 Somnolence, stupor and coma
0.824 0.176 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.821 0.179 0.000
S80-S89 Injuries to the knee and lower leg
0.817 0.183 0.000
D60-D64 Aplastic and other anaemias
0.816 0.184 0.000
I22 Subsequent myocardial infarction
0.815 0.185 0.000
B34 Viral infection of unspecified site
0.814 0.186 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.812 0.188 0.000
B35-B49 Mycoses
0.812 0.188 0.000
R06.5 Mouth breathing
0.811 0.189 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.810 0.190 0.000
X10-X19 Contact with heat and hot substances
0.809 0.191 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.808 0.192 0.000
R35 Polyuria
0.808 0.192 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.806 0.194 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.804 0.196 0.000
S42 Fracture of shoulder and upper arm
0.803 0.197 0.000
J18.0 Bronchopneumonia, unspecified
0.802 0.198 0.000
M79.6 Pain in limb
0.802 0.198 0.000
I62 Other nontraumatic intracranial haemorrhage
0.800 0.200 0.000
M20.2 Hallux rigidus
0.800 0.200 0.000
Y52 Agents primarily affecting the cardiovascular system
0.799 0.201 0.000
S40 Superficial injury of shoulder and upper arm
0.798 0.202 0.000
W20-W49 Exposure to inanimate mechanical forces
0.798 0.202 0.000
I24 Other acute ischaemic heart diseases
0.797 0.203 0.000
A04 Other bacterial intestinal infections
0.796 0.204 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.793 0.207 0.000
I63.9 Cerebral infarction, unspecified
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
I31.3 Pericardial effusion (noninflammatory)
0.788 0.212 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.787 0.213 0.000
M47 Spondylosis
0.786 0.214 0.000
R29.6 Tendency to fall, not elsewhere classified
0.786 0.214 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.785 0.215 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.783 0.217 0.000
S10-S19 Injuries to the neck
0.780 0.219 0.000
S06 Intracranial injury
0.780 0.220 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.776 0.224 0.000
M21 Other acquired deformities of limbs
0.774 0.225 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.774 0.226 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.774 0.226 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.774 0.226 0.000
J40-J47 Chronic lower respiratory diseases
0.773 0.227 0.000
R06.2 Wheezing
0.768 0.232 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.767 0.233 0.000
Chapter V Mental and behavioural disorders
0.767 0.233 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.767 0.233 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.765 0.235 0.000
I77 Other disorders of arteries and arterioles
0.765 0.235 0.000
Z04 Examination and observation for other reasons
0.765 0.235 0.000
R26 Abnormalities of gait and mobility
0.764 0.236 0.000
X60-X84 Intentional self-harm
0.763 0.237 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.763 0.237 0.000
Y40 Systemic antibiotics
0.761 0.239 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.761 0.239 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.760 0.240 0.000
B34.9 Viral infection, unspecified
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.757 0.243 0.000
M31 Other necrotising vasculopathies
0.757 0.243 0.000
A80-A89 Viral infections of the central nervous system
0.757 0.243 0.000
M50-M54 Other dorsopathies
0.756 0.244 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.750 0.250 0.000
I46 Cardiac arrest
0.749 0.251 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.748 0.252 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.748 0.252 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.747 0.253 0.000
R00 Abnormalities of heart beat
0.747 0.253 0.000
D64 Other anaemias
0.747 0.253 0.000
M80-M85 Disorders of bone density and structure
0.744 0.256 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.743 0.257 0.000
Z13 Special screening examination for other diseases and disorders
0.743 0.257 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.742 0.258 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.741 0.258 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.741 0.259 0.000
I69.3 Sequelae of cerebral infarction
0.740 0.260 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.740 0.260 0.000
M22 Disorders of patella
0.740 0.260 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.738 0.262 0.000
M20.4 Other hammer toe(s) (acquired)
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.735 0.265 0.000
I67 Other cerebrovascular diseases
0.735 0.265 0.000
Z72 Problems related to lifestyle
0.734 0.266 0.000
R49 Voice disturbances
0.732 0.267 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.732 0.268 0.000
S20-S29 Injuries to the thorax
0.731 0.269 0.000
I74 Arterial embolism and thrombosis
0.730 0.270 0.000
J91 Pleural effusion in conditions classified elsewhere
0.729 0.271 0.000
S00.8 Superficial injury of other parts of head
0.727 0.273 0.000
Z12 Special screening examination for neoplasms
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
J98.4 Other disorders of lung
0.725 0.275 0.000
Z36.8 Other antenatal screening
0.724 0.276 0.000
D50-D53 Nutritional anaemias
0.724 0.276 0.000
I21 Acute myocardial infarction
0.719 0.281 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.719 0.281 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
M72 Fibroblastic disorders
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
B15-B19 Viral hepatitis
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
S80 Superficial injury of lower leg
0.715 0.285 0.000
R40.2 Coma, unspecified
0.714 0.285 0.000
J17 Pneumonia in diseases classified elsewhere
0.714 0.286 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.714 0.286 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.714 0.286 0.000
J12 Viral pneumonia, not elsewhere classified
0.714 0.286 0.000
J11 Influenza, virus not identified
0.714 0.286 0.000
J10 Influenza due to identified influenza virus
0.714 0.286 0.000
J14 Pneumonia due to Haemophilus influenzae
0.714 0.286 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.714 0.286 0.000
J09 Influenza due to certain identified influenza virus
0.714 0.286 0.000
M47.8 Other spondylosis
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.5 Ischaemic cardiomyopathy
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.287 0.000
J18.2 Hypostatic pneumonia, unspecified
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
M45 Ankylosing spondylitis
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
I47 Paroxysmal tachycardia
0.711 0.289 0.000
J30-J39 Other diseases of upper respiratory tract
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
W19 Unspecified fall
0.709 0.291 0.000
I26 Pulmonary embolism
0.708 0.292 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.708 0.292 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.707 0.293 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.707 0.293 0.000
I70 Atherosclerosis
0.706 0.293 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S05 Injury of eye and orbit
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
R09.1 Pleurisy
0.705 0.295 0.000
M46 Other inflammatory spondylopathies
0.705 0.295 0.000
S01 Open wound of head
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.702 0.298 0.000
M34 Systemic sclerosis
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
M32 Systemic lupus erythematosus
0.702 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.701 0.299 0.000
A07 Other protozoal intestinal diseases
0.700 0.300 0.000
A06 Amoebiasis
0.700 0.300 0.000
A05 Other bacterial foodborne intoxications
0.700 0.300 0.000
A03 Shigellosis
0.700 0.300 0.000
A02 Other Salmonella infections
0.700 0.300 0.000
A01 Typhoid and paratyphoid fevers
0.700 0.300 0.000
A00 Cholera
0.700 0.300 0.000
M20.3 Other deformity of hallux (acquired)
0.700 0.300 0.000
M20.0 Deformity of finger(s)
0.700 0.300 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.699 0.301 0.000
Z10 Routine general health check-up of defined subpopulation
0.699 0.301 0.000
R06.0 Dyspnoea
0.699 0.301 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.698 0.302 0.000
D64.9 Anaemia, unspecified
0.697 0.303 0.000
I31.9 Disease of pericardium, unspecified
0.696 0.304 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.696 0.304 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.695 0.305 0.000
Y58 Bacterial vaccines
0.695 0.305 0.000
Y57 Other and unspecified drugs and medicaments
0.695 0.305 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.695 0.305 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.695 0.305 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.695 0.305 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.695 0.305 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.695 0.305 0.000
Y48 Anaesthetics and therapeutic gases
0.695 0.305 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.695 0.305 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.695 0.305 0.000
Y44 Agents primarily affecting blood constituents
0.695 0.305 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
M79.62 Pain in limb (Upper arm)
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.693 0.307 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.693 0.307 0.000
S40.0 Contusion of shoulder and upper arm
0.693 0.307 0.000
I60 Subarachnoid haemorrhage
0.692 0.308 0.000
R40.0 Somnolence
0.692 0.308 0.000
R07 Pain in throat and chest
0.692 0.308 0.000
Z35 Supervision of high-risk pregnancy
0.691 0.309 0.000
S00.1 Contusion of eyelid and periocular area
0.689 0.311 0.000
Z39 Postpartum care and examination
0.688 0.311 0.000
Z38 Liveborn infants according to place of birth
0.688 0.311 0.000
Z32 Pregnancy examination and test
0.688 0.311 0.000
Z31 Procreative management
0.688 0.311 0.000
Z33 Pregnant state, incidental
0.688 0.311 0.000
Chapter VI Diseases of the nervous system
0.687 0.313 0.000
S09.8 Other specified injuries of head
0.687 0.313 0.000
S09.7 Multiple injuries of head
0.687 0.313 0.000
S09.2 Traumatic rupture of ear drum
0.687 0.313 0.000
S09.1 Injury of muscle and tendon of head
0.687 0.313 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.687 0.313 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.687 0.313 0.000
J96 Respiratory failure, not elsewhere classified
0.687 0.313 0.000
R33 Retention of urine
0.687 0.313 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.686 0.314 0.000
J60-J70 Lung diseases due to external agents
0.686 0.314 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.686 0.314 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.685 0.314 0.000
I63.8 Other cerebral infarction
0.685 0.315 0.000
I80 Phlebitis and thrombophlebitis
0.683 0.317 0.000
I38 Endocarditis, valve unspecified
0.683 0.317 0.000
I20.1 Angina pectoris with documented spasm
0.683 0.317 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.683 0.317 0.000
J94 Other pleural conditions
0.682 0.318 0.000
I42 Cardiomyopathy
0.682 0.318 0.000
W18 Other fall on same level
0.682 0.318 0.000
R09.2 Respiratory arrest
0.682 0.318 0.000
B35 Dermatophytosis
0.681 0.319 0.000
I10-I15 Hypertensive diseases
0.681 0.319 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.681 0.319 0.000
A04.8 Other specified bacterial intestinal infections
0.680 0.320 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.680 0.320 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.678 0.321 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.678 0.322 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.677 0.323 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.677 0.323 0.000
I20.9 Angina pectoris, unspecified
0.677 0.323 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.676 0.324 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.675 0.325 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.675 0.325 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.674 0.325 0.000
I77.1 Stricture of artery
0.674 0.326 0.000
M24 Other specific joint derangements
0.674 0.326 0.000
M77 Other enthesopathies
0.673 0.326 0.000
D55-D59 Haemolytic anaemias
0.672 0.328 0.000
T51 Toxic effect of alcohol
0.672 0.328 0.000
W07 Fall involving chair
0.672 0.328 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.670 0.330 0.000
R04 Haemorrhage from respiratory passages
0.670 0.330 0.000
Z76 Persons encountering health services in other circumstances
0.669 0.331 0.000
Z73 Problems related to life-management difficulty
0.669 0.331 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.669 0.331 0.000
A08 Viral and other specified intestinal infections
0.669 0.331 0.000
Y95 Nosocomial condition
0.669 0.331 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.668 0.332 0.000
M54 Dorsalgia
0.666 0.334 0.000
S48 Traumatic amputation of shoulder and upper arm
0.666 0.334 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.666 0.334 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.666 0.334 0.000
S44 Injury of nerves at shoulder and upper arm level
0.666 0.334 0.000
S41 Open wound of shoulder and upper arm
0.666 0.334 0.000
S47 Crushing injury of shoulder and upper arm
0.666 0.334 0.000
J98.9 Respiratory disorder, unspecified
0.666 0.334 0.000
J98.8 Other specified respiratory disorders
0.666 0.334 0.000
J98.6 Disorders of diaphragm
0.666 0.334 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.666 0.334 0.000
J98.3 Compensatory emphysema
0.666 0.334 0.000
J98.2 Interstitial emphysema
0.666 0.334 0.000
I33 Acute and subacute endocarditis
0.665 0.335 0.000
S00.9 Superficial injury of head, part unspecified
0.664 0.336 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.662 0.338 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.662 0.338 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.661 0.339 0.000
A30-A49 Other bacterial diseases
0.661 0.339 0.000
M79.1 Myalgia
0.661 0.339 0.000
D80-D89 Certain disorders involving the immune mechanism
0.661 0.339 0.000
S42.2 Fracture of upper end of humerus
0.661 0.339 0.000
R09.0 Asphyxia
0.659 0.341 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.658 0.341 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.658 0.342 0.000
R45 Symptoms and signs involving emotional state
0.655 0.345 0.000
Y43.9 Primarily systemic agent, unspecified
0.655 0.345 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.655 0.345 0.000
Y43.6 Enzymes, not elsewhere classified
0.655 0.345 0.000
Y43.5 Acidifying and alkalising agents
0.655 0.345 0.000
Y43.4 Immunosuppressive agents
0.655 0.345 0.000
Y43.2 Antineoplastic natural products
0.655 0.345 0.000
Y43.1 Antineoplastic antimetabolites
0.655 0.345 0.000
Y43.0 Antiallergic and antiemetic drugs
0.655 0.345 0.000
Z30.9 Contraceptive management, unspecified
0.655 0.345 0.000
Z30.8 Other contraceptive management
0.655 0.345 0.000
Z30.4 Surveillance of contraceptive drugs
0.655 0.345 0.000
Z30.3 Menstrual extraction
0.655 0.345 0.000
Z30.0 General counselling and advice on contraception
0.655 0.345 0.000
I50 Heart failure
0.654 0.346 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.653 0.347 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
M76 Enthesopathies of lower limb, excluding foot
0.653 0.347 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.653 0.347 0.000
M71 Other bursopathies
0.653 0.347 0.000
I78 Diseases of capillaries
0.652 0.348 0.000
R46 Symptoms and signs involving appearance and behaviour
0.652 0.348 0.000
R43 Disturbances of smell and taste
0.652 0.348 0.000
Z60 Problems related to social environment
0.651 0.348 0.000
R41.3 Other amnesia
0.651 0.349 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.650 0.350 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.650 0.350 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.650 0.350 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.650 0.350 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.650 0.350 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.650 0.350 0.000
T66-T78 Other and unspecified effects of external causes
0.648 0.351 0.000
M79.60 Pain in limb (Multiple sites)
0.648 0.351 0.000
W06 Fall involving bed
0.648 0.352 0.000
R49.0 Dysphonia
0.648 0.352 0.000
Z72.0 Tobacco use
0.648 0.352 0.000
R74 Abnormal serum enzyme levels
0.648 0.352 0.000
Chapter VII Diseases of the eye and adnexa
0.648 0.352 0.000
I52 Other heart disorders in diseases classified elsewhere
0.647 0.353 0.000
I48 Atrial fibrillation and flutter
0.647 0.353 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.647 0.353 0.000
I41 Myocarditis in diseases classified elsewhere
0.647 0.353 0.000
I40 Acute myocarditis
0.647 0.353 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.647 0.353 0.000
I37 Pulmonary valve disorders
0.647 0.353 0.000
I36 Nonrheumatic tricuspid valve disorders
0.647 0.353 0.000
I32 Pericarditis in diseases classified elsewhere
0.647 0.353 0.000
I30 Acute pericarditis
0.647 0.353 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.647 0.353 0.000
R06.7 Sneezing
0.645 0.355 0.000
R06.6 Hiccough
0.645 0.355 0.000
R06.4 Hyperventilation
0.645 0.355 0.000
R06.3 Periodic breathing
0.645 0.355 0.000
R06.1 Stridor
0.645 0.355 0.000
R00.2 Palpitations
0.645 0.355 0.000
Z71.9 Counselling, unspecified
0.644 0.356 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.644 0.356 0.000
R27 Other lack of coordination
0.644 0.356 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.643 0.357 0.000
J44 Other chronic obstructive pulmonary disease
0.642 0.358 0.000
Z50 Care involving use of rehabilitation procedures
0.642 0.358 0.000
Z71.8 Other specified counselling
0.641 0.359 0.000
Z36.5 Antenatal screening for isoimmunisation
0.641 0.359 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.641 0.359 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.641 0.359 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.641 0.359 0.000
M49 Spondylopathies in diseases classified elsewhere
0.641 0.359 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.641 0.359 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.640 0.360 0.000
S02 Fracture of skull and facial bones
0.640 0.360 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.640 0.360 0.000
S42.0 Fracture of clavicle
0.639 0.361 0.000
R47 Speech disturbances, not elsewhere classified
0.639 0.361 0.000
R02 Gangrene, not elsewhere classified
0.639 0.361 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.638 0.361 0.000
I72 Other aneurysm
0.638 0.361 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.638 0.362 0.000
B33 Other viral diseases, not elsewhere classified
0.638 0.362 0.000
B30 Viral conjunctivitis
0.638 0.362 0.000
B27 Infectious mononucleosis
0.638 0.362 0.000
B26 Mumps
0.638 0.362 0.000
B25 Cytomegaloviral disease
0.638 0.362 0.000
S81 Open wound of lower leg
0.638 0.362 0.000
M95.0 Acquired deformity of nose
0.637 0.363 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.636 0.364 0.000
M79.66 Pain in limb (Lower leg)
0.635 0.365 0.000
Z04.8 Examination and observation for other specified reasons
0.635 0.365 0.000
Chapter VIII Diseases of the ear and mastoid process
0.634 0.366 0.000
M47.2 Other spondylosis with radiculopathy
0.634 0.366 0.000
Z74 Problems related to care-provider dependency
0.633 0.366 0.000
S00.0 Superficial injury of scalp
0.633 0.367 0.000
M65-M68 Disorders of synovium and tendon
0.633 0.367 0.000
T17 Foreign body in respiratory tract
0.631 0.369 0.000
J92 Pleural plaque
0.630 0.369 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.630 0.370 0.000
R30 Pain associated with micturition
0.630 0.370 0.000
W44 Foreign body entering into or through eye or natural orifice
0.630 0.370 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.629 0.370 0.000
J43 Emphysema
0.629 0.371 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.629 0.371 0.000
J38.3 Other diseases of vocal cords
0.628 0.372 0.000
Chapter XI Diseases of the digestive system
0.627 0.373 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.626 0.374 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.625 0.375 0.000
M47.86 Other spondylosis (Lumbar region)
0.625 0.375 0.000
K70-K77 Diseases of liver
0.625 0.375 0.000
W17 Other fall from one level to another
0.624 0.376 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.624 0.376 0.000
W15 Fall from cliff
0.624 0.376 0.000
W14 Fall from tree
0.624 0.376 0.000
W13 Fall from, out of or through building or structure
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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