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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73154143
log Bayes Factor = 22.4344
Chromosome 22   position 26,354,531  (GRCh37) Explore rs73154143 on Ensembl!
Variant rs73154143 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
I20 Angina pectoris
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
I20.9 Angina pectoris, unspecified
0.990 0.010 0.000
Chapter II Neoplasms
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
Z85 Personal history of malignant neoplasm
0.982 0.018 0.000
Z86 Personal history of certain other diseases
0.979 0.021 0.000
Chapter I Certain infectious and parasitic diseases
0.975 0.025 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.973 0.027 0.000
E00-E07 Disorders of thyroid gland
0.971 0.029 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.969 0.031 0.000
T81 Complications of procedures, not elsewhere classified
0.968 0.032 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.968 0.032 0.000
Chapter XIV Diseases of the genitourinary system
0.967 0.033 0.000
G40 Epilepsy
0.966 0.034 0.000
Z86.4 Personal history of psychoactive substance abuse
0.963 0.037 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.962 0.038 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.962 0.038 0.000
S60-S69 Injuries to the wrist and hand
0.961 0.039 0.000
Z93 Artificial opening status
0.961 0.039 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.959 0.041 0.000
R50-R69 General symptoms and signs
0.958 0.042 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.956 0.044 0.000
R07 Pain in throat and chest
0.953 0.047 0.000
N81 Female genital prolapse
0.952 0.048 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.951 0.049 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.946 0.054 0.000
D00-D09 In situ neoplasms
0.946 0.054 0.000
G47 Sleep disorders
0.943 0.057 0.000
R07.3 Other chest pain
0.942 0.058 0.000
C51-C58 Malignant neoplasms of female genital organs
0.939 0.061 0.000
N85.2 Hypertrophy of uterus
0.938 0.062 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.937 0.063 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.936 0.064 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.934 0.066 0.000
Chapter X Diseases of the respiratory system
0.928 0.072 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.928 0.072 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.921 0.079 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.919 0.081 0.000
I50 Heart failure
0.919 0.081 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.919 0.081 0.000
R53 Malaise and fatigue
0.915 0.085 0.000
N81.4 Uterovaginal prolapse, unspecified
0.910 0.090 0.000
R04 Haemorrhage from respiratory passages
0.909 0.091 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.909 0.091 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.905 0.095 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.903 0.097 0.000
E04 Other non-toxic goitre
0.902 0.098 0.000
R59 Enlarged lymph nodes
0.900 0.100 0.000
G40.9 Epilepsy, unspecified
0.900 0.100 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.898 0.102 0.000
I34 Nonrheumatic mitral valve disorders
0.895 0.105 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
B95-B98 Bacterial, viral and other infectious agents
0.892 0.108 0.000
C15-C26 Malignant neoplasms of digestive organs
0.886 0.114 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.884 0.116 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.880 0.120 0.000
C64-C68 Malignant neoplasms of urinary tract
0.878 0.122 0.000
I20.0 Unstable angina
0.877 0.123 0.000
Z95.2 Presence of prosthetic heart valve
0.875 0.125 0.000
E70-E90 Metabolic disorders
0.874 0.126 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.872 0.128 0.000
I44 Atrioventricular and left bundle-branch block
0.871 0.129 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.871 0.129 0.000
Z90.5 Acquired absence of kidney
0.871 0.129 0.000
R04.2 Haemoptysis
0.871 0.129 0.000
D05 Carcinoma in situ of breast
0.869 0.131 0.000
G90-G99 Other disorders of the nervous system
0.869 0.131 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.869 0.131 0.000
N17-N19 Renal failure
0.869 0.131 0.000
S60 Superficial injury of wrist and hand
0.868 0.132 0.000
M06 Other rheumatoid arthritis
0.867 0.133 0.000
G43 Migraine
0.867 0.133 0.000
R07.2 Precordial pain
0.866 0.134 0.000
E07 Other disorders of thyroid
0.866 0.134 0.000
C54 Malignant neoplasm of corpus uteri
0.865 0.135 0.000
Z93.2 Ileostomy status
0.865 0.135 0.000
I35 Nonrheumatic aortic valve disorders
0.863 0.137 0.000
Y52 Agents primarily affecting the cardiovascular system
0.863 0.137 0.000
N89 Other noninflammatory disorders of vagina
0.862 0.138 0.000
Chapter VIII Diseases of the ear and mastoid process
0.862 0.138 0.000
N81.2 Incomplete uterovaginal prolapse
0.860 0.140 0.000
B35-B49 Mycoses
0.858 0.142 0.000
N85.4 Malposition of uterus
0.858 0.142 0.000
G47.3 Sleep apnoea
0.857 0.143 0.000
I60-I69 Cerebrovascular diseases
0.857 0.143 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.852 0.148 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.852 0.148 0.000
A30-A49 Other bacterial diseases
0.848 0.151 0.000
Z95.4 Presence of other heart-valve replacement
0.848 0.152 0.000
I22 Subsequent myocardial infarction
0.847 0.153 0.000
I45 Other conduction disorders
0.846 0.154 0.000
M06.9 Rheumatoid arthritis, unspecified
0.841 0.159 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.838 0.162 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.837 0.163 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.836 0.164 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.833 0.167 0.000
N81.1 Cystocele
0.833 0.167 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.832 0.168 0.000
O60-O75 Complications of labour and delivery
0.831 0.169 0.000
I05-I09 Chronic rheumatic heart diseases
0.828 0.172 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.828 0.172 0.000
G81 Hemiplegia
0.827 0.173 0.000
G40.8 Other epilepsy
0.826 0.173 0.000
T42.4 Benzodiazepines
0.826 0.174 0.000
I50.1 Left ventricular failure
0.826 0.174 0.000
Z35 Supervision of high-risk pregnancy
0.825 0.175 0.000
J40-J47 Chronic lower respiratory diseases
0.824 0.176 0.000
E20-E35 Disorders of other endocrine glands
0.823 0.177 0.000
R59.0 Localised enlarged lymph nodes
0.822 0.178 0.000
I34.0 Mitral (valve) insufficiency
0.822 0.178 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.821 0.178 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.821 0.179 0.000
G47.8 Other sleep disorders
0.820 0.180 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.818 0.182 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.814 0.186 0.000
C54.1 Endometrium
0.813 0.187 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.807 0.193 0.000
O00-O08 Pregnancy with abortive outcome
0.802 0.198 0.000
N18 Chronic renal failure
0.800 0.200 0.000
Z93.3 Colostomy status
0.798 0.201 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.798 0.202 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.797 0.203 0.000
Z90.3 Acquired absence of part of stomach
0.796 0.204 0.000
Z95.3 Presence of xenogenic heart valve
0.796 0.204 0.000
R63 Symptoms and signs concerning food and fluid intake
0.796 0.204 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.796 0.204 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.794 0.206 0.000
S61 Open wound of wrist and hand
0.794 0.206 0.000
S80-S89 Injuries to the knee and lower leg
0.794 0.206 0.000
E04.2 Non-toxic multinodular goitre
0.793 0.207 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.793 0.207 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.791 0.209 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.791 0.209 0.000
Y40 Systemic antibiotics
0.791 0.209 0.000
E07.9 Disorder of thyroid, unspecified
0.790 0.210 0.000
Z94 Transplanted organ and tissue status
0.790 0.210 0.000
I50.0 Congestive heart failure
0.789 0.211 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.789 0.211 0.000
T39.1 4-Aminophenol derivatives
0.789 0.211 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.788 0.212 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.788 0.212 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.787 0.213 0.000
Z90.1 Acquired absence of breast(s)
0.786 0.214 0.000
N93 Other abnormal uterine and vaginal bleeding
0.785 0.215 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.784 0.216 0.000
S62 Fracture at wrist and hand level
0.784 0.216 0.000
Z95.0 Presence of cardiac pacemaker
0.783 0.216 0.000
J44 Other chronic obstructive pulmonary disease
0.783 0.217 0.000
Y43 Primarily systemic agents
0.782 0.217 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.782 0.218 0.000
S60.8 Other superficial injuries of wrist and hand
0.782 0.218 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.782 0.218 0.000
R42 Dizziness and giddiness
0.781 0.219 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.781 0.219 0.000
R25 Abnormal involuntary movements
0.781 0.219 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.780 0.220 0.000
J90-J94 Other diseases of pleura
0.780 0.220 0.000
S40-S49 Injuries to the shoulder and upper arm
0.779 0.221 0.000
G43.9 Migraine, unspecified
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.776 0.224 0.000
J30-J39 Other diseases of upper respiratory tract
0.776 0.224 0.000
I95 Hypotension
0.774 0.226 0.000
I20.8 Other forms of angina pectoris
0.774 0.226 0.000
Z90.2 Acquired absence of lung [part of]
0.774 0.226 0.000
J00-J06 Acute upper respiratory infections
0.774 0.226 0.000
R52 Pain, not elsewhere classified
0.773 0.227 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.773 0.227 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
W20-W49 Exposure to inanimate mechanical forces
0.771 0.229 0.000
Z80 Family history of malignant neoplasm
0.768 0.232 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.766 0.234 0.000
B37 Candidiasis
0.766 0.234 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.765 0.235 0.000
E65-E68 Obesity and other hyperalimentation
0.765 0.235 0.000
Z93.1 Gastrostomy status
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.764 0.236 0.000
N85.0 Endometrial glandular hyperplasia
0.764 0.236 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.763 0.237 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.763 0.237 0.000
Z31 Procreative management
0.762 0.238 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.762 0.238 0.000
D03 Melanoma in situ
0.762 0.238 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.762 0.238 0.000
I35.1 Aortic (valve) insufficiency
0.761 0.239 0.000
R59.9 Enlarged lymph nodes, unspecified
0.761 0.239 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.761 0.239 0.000
Z36 Antenatal screening
0.760 0.240 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.760 0.240 0.000
A49 Bacterial infection of unspecified site
0.760 0.240 0.000
R11 Nausea and vomiting
0.758 0.242 0.000
D04 Carcinoma in situ of skin
0.758 0.242 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
M86-M90 Other osteopathies
0.756 0.244 0.000
G83 Other paralytic syndromes
0.756 0.244 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.756 0.244 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.755 0.245 0.000
G81.9 Hemiplegia, unspecified
0.755 0.245 0.000
C67 Malignant neoplasm of bladder
0.754 0.246 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.753 0.247 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.752 0.247 0.000
N92 Excessive, frequent and irregular menstruation
0.752 0.248 0.000
C51 Malignant neoplasm of vulva
0.750 0.250 0.000
I44.0 Atrioventricular block, first degree
0.750 0.250 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.750 0.250 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.749 0.251 0.000
M20-M25 Other joint disorders
0.748 0.252 0.000
R09.0 Asphyxia
0.748 0.252 0.000
M50-M54 Other dorsopathies
0.747 0.253 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.747 0.253 0.000
C18 Malignant neoplasm of colon
0.747 0.253 0.000
Z93.0 Tracheostomy status
0.747 0.253 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.746 0.254 0.000
C56 Malignant neoplasm of ovary
0.745 0.255 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.745 0.255 0.000
I25 Chronic ischaemic heart disease
0.744 0.256 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.743 0.257 0.000
G93 Other disorders of brain
0.743 0.257 0.000
Y83.3 Surgical operation with formation of external stoma
0.743 0.257 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.743 0.257 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.742 0.258 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.741 0.259 0.000
I46 Cardiac arrest
0.741 0.259 0.000
E05.9 Thyrotoxicosis, unspecified
0.740 0.260 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.740 0.260 0.000
O02 Other abnormal products of conception
0.740 0.260 0.000
E04.1 Non-toxic single thyroid nodule
0.739 0.261 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.736 0.264 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.735 0.265 0.000
I45.6 Preexcitation syndrome
0.735 0.265 0.000
Z89 Acquired absence of limb
0.734 0.266 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.733 0.267 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.733 0.267 0.000
N18.3 Chronic kidney disease, stage 3
0.732 0.268 0.000
C25 Malignant neoplasm of pancreas
0.731 0.269 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.730 0.270 0.000
N88 Other noninflammatory disorders of cervix uteri
0.729 0.271 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.729 0.271 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.726 0.273 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.726 0.274 0.000
I35.9 Aortic valve disorder, unspecified
0.725 0.275 0.000
H65-H75 Diseases of middle ear and mastoid
0.725 0.275 0.000
A00-A09 Intestinal infectious diseases
0.725 0.275 0.000
T39.0 Salicylates
0.724 0.276 0.000
H60-H62 Diseases of external ear
0.724 0.276 0.000
M91-M94 Chondropathies
0.722 0.278 0.000
M05 Seropositive rheumatoid arthritis
0.722 0.278 0.000
Z85.6 Personal history of leukaemia
0.722 0.278 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
R47-R49 Symptoms and signs involving speech and voice
0.719 0.281 0.000
E04.9 Non-toxic goitre, unspecified
0.719 0.281 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.718 0.282 0.000
Z12 Special screening examination for neoplasms
0.717 0.283 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
Z90.8 Acquired absence of other organs
0.715 0.285 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
Z93.6 Other artificial openings of urinary tract status
0.714 0.286 0.000
I44.1 Atrioventricular block, second degree
0.713 0.287 0.000
I20.1 Angina pectoris with documented spasm
0.713 0.287 0.000
N90.5 Atrophy of vulva
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.711 0.289 0.000
G41 Status epilepticus
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
W00-W19 Falls
0.709 0.291 0.000
R57 Shock, not elsewhere classified
0.709 0.291 0.000
Z39 Postpartum care and examination
0.709 0.291 0.000
R54 Senility
0.709 0.291 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.709 0.291 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.709 0.291 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.708 0.292 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.707 0.293 0.000
R63.0 Anorexia
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
I49 Other cardiac arrhythmias
0.706 0.294 0.000
Z90.0 Acquired absence of part of head and neck
0.706 0.294 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.706 0.294 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.706 0.294 0.000
E78.5 Hyperlipidaemia, unspecified
0.705 0.295 0.000
D09 Carcinoma in situ of other and unspecified sites
0.705 0.295 0.000
S69 Other and unspecified injuries of wrist and hand
0.704 0.295 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.704 0.296 0.000
Y83.6 Removal of other organ (partial) (total)
0.704 0.296 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.704 0.296 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.704 0.296 0.000
B15-B19 Viral hepatitis
0.704 0.296 0.000
G80 Infantile cerebral palsy
0.704 0.296 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.703 0.297 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.702 0.298 0.000
G47.9 Sleep disorder, unspecified
0.701 0.298 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.701 0.299 0.000
E83 Disorders of mineral metabolism
0.701 0.299 0.000
Z93.5 Cystostomy status
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.299 0.000
T82.3 Mechanical complication of other vascular grafts
0.700 0.300 0.000
B99-B99 Other infectious diseases
0.699 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B65-B83 Helminthiases
0.699 0.301 0.000
B50-B64 Protozoal diseases
0.699 0.301 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A80-A89 Viral infections of the central nervous system
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.698 0.302 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.698 0.302 0.000
V20-V29 Motorcycle rider injured in transport accident
0.697 0.303 0.000
J91 Pleural effusion in conditions classified elsewhere
0.696 0.303 0.000
E28 Ovarian dysfunction
0.696 0.304 0.000
E06 Thyroiditis
0.696 0.304 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.696 0.304 0.000
E00 Congenital iodine-deficiency syndrome
0.696 0.304 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.696 0.304 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.696 0.304 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.696 0.304 0.000
S68 Traumatic amputation of wrist and hand
0.696 0.304 0.000
Chapter XI Diseases of the digestive system
0.696 0.304 0.000
M06.0 Seronegative rheumatoid arthritis
0.696 0.304 0.000
R56 Convulsions, not elsewhere classified
0.695 0.305 0.000
B37.8 Candidiasis of other sites
0.695 0.305 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.695 0.305 0.000
T81.9 Unspecified complication of procedure
0.694 0.306 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.694 0.306 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.694 0.306 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.694 0.306 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.694 0.306 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
N98 Complications associated with artificial fertilisation
0.694 0.306 0.000
N91 Absent, scanty and rare menstruation
0.694 0.306 0.000
N82 Fistulae involving female genital tract
0.694 0.306 0.000
N96 Habitual aborter
0.694 0.306 0.000
G82 Paraplegia and tetraplegia
0.694 0.306 0.000
R60 Oedema, not elsewhere classified
0.693 0.307 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.692 0.307 0.000
G40.5 Special epileptic syndromes
0.692 0.307 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.692 0.307 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.692 0.307 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.692 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.691 0.309 0.000
I33 Acute and subacute endocarditis
0.690 0.310 0.000
R68 Other general symptoms and signs
0.690 0.310 0.000
Y44 Agents primarily affecting blood constituents
0.690 0.310 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
N85.7 Haematometra
0.690 0.310 0.000
N85.6 Intra-uterine synechiae
0.690 0.310 0.000
N85.5 Inversion of uterus
0.690 0.310 0.000
N85.3 Subinvolution of uterus
0.690 0.310 0.000
N85.1 Endometrial adenomatous hyperplasia
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.689 0.311 0.000
S67 Crushing injury of wrist and hand
0.689 0.311 0.000
S65 Injury of blood vessels at wrist and hand level
0.689 0.311 0.000
Z93.9 Artificial opening status, unspecified
0.689 0.311 0.000
Z93.8 Other artificial opening status
0.689 0.311 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.689 0.311 0.000
I08 Multiple valve diseases
0.688 0.312 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.687 0.313 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.687 0.313 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.687 0.313 0.000
R62 Lack of expected normal physiological development
0.687 0.313 0.000
R64 Cachexia
0.687 0.313 0.000
R58 Haemorrhage, not elsewhere classified
0.687 0.313 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.686 0.314 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.686 0.314 0.000
Z97 Presence of other devices
0.686 0.314 0.000
J34 Other disorders of nose and nasal sinuses
0.685 0.315 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.685 0.315 0.000
C53 Malignant neoplasm of cervix uteri
0.685 0.315 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.684 0.316 0.000
R07.1 Chest pain on breathing
0.684 0.316 0.000
I24 Other acute ischaemic heart diseases
0.683 0.317 0.000
J47 Bronchiectasis
0.683 0.317 0.000
N81.0 Female urethrocele
0.682 0.318 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.682 0.318 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.681 0.319 0.000
Y83.4 Other reconstructive surgery
0.680 0.320 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.680 0.320 0.000
N97 Female infertility
0.679 0.321 0.000
N90.7 Vulvar cyst
0.679 0.321 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.678 0.322 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.678 0.322 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.678 0.322 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.678 0.322 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.677 0.323 0.000
N18.0 End-stage renal disease
0.677 0.323 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.676 0.324 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.676 0.324 0.000
G47.4 Narcolepsy and cataplexy
0.676 0.324 0.000
G47.2 Disorders of the sleep-wake schedule
0.676 0.324 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.676 0.324 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.676 0.324 0.000
I99 Other and unspecified disorders of circulatory system
0.676 0.324 0.000
I25.2 Old myocardial infarction
0.675 0.325 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
Z36.8 Other antenatal screening
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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