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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73155954
log Bayes Factor = 14.0489
Chromosome 13   position 26,542,052  (GRCh37) Explore rs73155954 on Ensembl!
Variant rs73155954 is part of Cluster X0185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M54 Dorsalgia
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.999 0.001 0.000
R14 Flatulence and related conditions
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.991 0.009 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.990 0.010 0.000
R12 Heartburn
0.988 0.012 0.000
N17-N19 Renal failure
0.986 0.014 0.000
N18 Chronic renal failure
0.984 0.016 0.000
N25-N29 Other disorders of kidney and ureter
0.983 0.017 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.981 0.019 0.000
I45 Other conduction disorders
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.979 0.021 0.000
N18.3 Chronic kidney disease, stage 3
0.978 0.022 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.977 0.023 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.977 0.023 0.000
I47 Paroxysmal tachycardia
0.975 0.025 0.000
Chapter II Neoplasms
0.970 0.030 0.000
I25.2 Old myocardial infarction
0.969 0.031 0.000
M47 Spondylosis
0.969 0.031 0.000
D00-D09 In situ neoplasms
0.967 0.033 0.000
D05 Carcinoma in situ of breast
0.964 0.036 0.000
M54.5 Low back pain
0.962 0.038 0.000
I47.1 Supraventricular tachycardia
0.961 0.039 0.000
Y95 Nosocomial condition
0.960 0.040 0.000
M46 Other inflammatory spondylopathies
0.958 0.042 0.000
I73 Other peripheral vascular diseases
0.958 0.042 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.957 0.043 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.957 0.043 0.000
D05.1 Intraductal carcinoma in situ
0.956 0.044 0.000
M06 Other rheumatoid arthritis
0.955 0.045 0.000
M06.9 Rheumatoid arthritis, unspecified
0.943 0.057 0.000
I49 Other cardiac arrhythmias
0.940 0.060 0.000
M47.8 Other spondylosis
0.938 0.062 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
I73.9 Peripheral vascular disease, unspecified
0.935 0.065 0.000
M54.56 Low back pain (Lumbar region)
0.930 0.070 0.000
M54.1 Radiculopathy
0.929 0.071 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.928 0.072 0.000
S20-S29 Injuries to the thorax
0.927 0.073 0.000
M54.3 Sciatica
0.927 0.073 0.000
I77 Other disorders of arteries and arterioles
0.924 0.076 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.915 0.085 0.000
M47.86 Other spondylosis (Lumbar region)
0.909 0.091 0.000
M54.6 Pain in thoracic spine
0.900 0.100 0.000
M45 Ankylosing spondylitis
0.899 0.101 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.899 0.101 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.892 0.108 0.000
R20 Disturbances of skin sensation
0.890 0.110 0.000
A30-A49 Other bacterial diseases
0.889 0.111 0.000
N28.8 Other specified disorders of kidney and ureter
0.889 0.111 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.889 0.111 0.000
Chapter V Mental and behavioural disorders
0.888 0.112 0.000
D04 Carcinoma in situ of skin
0.888 0.112 0.000
B15-B19 Viral hepatitis
0.885 0.115 0.000
B02 Zoster [herpes zoster]
0.884 0.116 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.883 0.117 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.879 0.121 0.000
M54.2 Cervicalgia
0.877 0.123 0.000
X60-X84 Intentional self-harm
0.876 0.124 0.000
N28.0 Ischaemia and infarction of kidney
0.875 0.125 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.874 0.126 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.873 0.127 0.000
M54.39 Sciatica (Site unspecified)
0.872 0.128 0.000
M60-M63 Disorders of muscles
0.872 0.128 0.000
N00-N08 Glomerular diseases
0.866 0.134 0.000
R20.2 Paraesthesia of skin
0.863 0.137 0.000
N28.1 Cyst of kidney, acquired
0.863 0.137 0.000
I38 Endocarditis, valve unspecified
0.863 0.137 0.000
I44 Atrioventricular and left bundle-branch block
0.862 0.138 0.000
N18.0 End-stage renal disease
0.859 0.141 0.000
I20 Angina pectoris
0.859 0.141 0.000
M54.16 Radiculopathy (Lumbar region)
0.859 0.141 0.000
N18.5 Chronic kidney disease, stage 5
0.858 0.142 0.000
R29.6 Tendency to fall, not elsewhere classified
0.855 0.145 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.854 0.146 0.000
I46 Cardiac arrest
0.853 0.147 0.000
I77.6 Arteritis, unspecified
0.853 0.147 0.000
D05.0 Lobular carcinoma in situ
0.850 0.150 0.000
M51 Other intervertebral disk disorders
0.848 0.152 0.000
I21 Acute myocardial infarction
0.844 0.156 0.000
I44.1 Atrioventricular block, second degree
0.843 0.157 0.000
F60-F69 Disorders of adult personality and behaviour
0.843 0.157 0.000
I45.1 Other and unspecified right bundle-branch block
0.841 0.159 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.840 0.160 0.000
N99-N99 Other disorders of the genitourinary system
0.839 0.161 0.000
I49.0 Ventricular fibrillation and flutter
0.838 0.162 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.836 0.164 0.000
M40-M43 Deforming dorsopathies
0.836 0.164 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.835 0.165 0.000
R11 Nausea and vomiting
0.833 0.167 0.000
M54.19 Radiculopathy (Site unspecified)
0.833 0.167 0.000
M86-M90 Other osteopathies
0.832 0.168 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.830 0.170 0.000
C15-C26 Malignant neoplasms of digestive organs
0.828 0.172 0.000
I45.5 Other specified heart block
0.828 0.172 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.827 0.173 0.000
R23 Other skin changes
0.824 0.176 0.000
I72 Other aneurysm
0.822 0.178 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.822 0.178 0.000
B02.9 Zoster without complication
0.821 0.179 0.000
B18 Chronic viral hepatitis
0.820 0.180 0.000
S22.0 Fracture of thoracic vertebra
0.819 0.181 0.000
I77.1 Stricture of artery
0.819 0.181 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.817 0.183 0.000
S00-S09 Injuries to the head
0.815 0.185 0.000
M46.4 Discitis, unspecified
0.814 0.186 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.813 0.187 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.812 0.188 0.000
F60 Specific personality disorders
0.810 0.190 0.000
I24 Other acute ischaemic heart diseases
0.810 0.190 0.000
V80-V89 Other land transport accidents
0.810 0.190 0.000
I45.9 Conduction disorder, unspecified
0.808 0.192 0.000
R25 Abnormal involuntary movements
0.806 0.194 0.000
Q60-Q64 Congenital malformations of the urinary system
0.805 0.195 0.000
I20.9 Angina pectoris, unspecified
0.805 0.195 0.000
A46 Erysipelas
0.804 0.196 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.804 0.196 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.804 0.196 0.000
I37 Pulmonary valve disorders
0.803 0.197 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.803 0.197 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.802 0.198 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.801 0.199 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.799 0.201 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.799 0.201 0.000
W50-W64 Exposure to animate mechanical forces
0.797 0.203 0.000
I45.2 Bifascicular block
0.795 0.205 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.795 0.205 0.000
R27 Other lack of coordination
0.793 0.207 0.000
B50-B64 Protozoal diseases
0.792 0.207 0.000
C69 Malignant neoplasm of eye and adnexa
0.792 0.207 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.791 0.209 0.000
T93 Sequelae of injuries of lower limb
0.790 0.210 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.789 0.211 0.000
I49.9 Cardiac arrhythmia, unspecified
0.789 0.211 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.789 0.211 0.000
S90-S99 Injuries to the ankle and foot
0.787 0.212 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.787 0.213 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.785 0.215 0.000
D04.6 Skin of upper limb, including shoulder
0.783 0.217 0.000
C73 Malignant neoplasm of thyroid gland
0.780 0.220 0.000
I33 Acute and subacute endocarditis
0.780 0.220 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.780 0.220 0.000
N18.8 Other chronic renal failure
0.779 0.221 0.000
I45.8 Other specified conduction disorders
0.778 0.222 0.000
I60-I69 Cerebrovascular diseases
0.778 0.222 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.777 0.223 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.777 0.223 0.000
I46.0 Cardiac arrest with successful resuscitation
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
S06 Intracranial injury
0.774 0.226 0.000
I45.4 Nonspecific intraventricular block
0.773 0.226 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.773 0.227 0.000
I31 Other diseases of pericardium
0.771 0.229 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.770 0.230 0.000
M13 Other arthritis
0.769 0.231 0.000
M47.82 Other spondylosis (Cervical region)
0.769 0.231 0.000
I30 Acute pericarditis
0.769 0.231 0.000
I49.1 Atrial premature depolarisation
0.768 0.232 0.000
M54.4 Lumbago with sciatica
0.768 0.232 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.766 0.234 0.000
I23 Certain current complications following acute myocardial infarction
0.766 0.234 0.000
F60.3 Emotionally unstable personality disorder
0.765 0.235 0.000
S22.4 Multiple fractures of ribs
0.764 0.236 0.000
I45.6 Preexcitation syndrome
0.763 0.237 0.000
M62 Other disorders of muscle
0.763 0.237 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.762 0.238 0.000
N17 Acute renal failure
0.760 0.240 0.000
M47.1 Other spondylosis with myelopathy
0.759 0.241 0.000
M53 Other dorsopathies, not elsewhere classified
0.759 0.241 0.000
R47-R49 Symptoms and signs involving speech and voice
0.759 0.241 0.000
M14 Arthropathies in other diseases classified elsewhere
0.759 0.241 0.000
D04.3 Skin of other and unspecified parts of face
0.755 0.245 0.000
Y48 Anaesthetics and therapeutic gases
0.755 0.245 0.000
M47.89 Other spondylosis (Site unspecified)
0.755 0.245 0.000
N05 Unspecified nephritic syndrome
0.754 0.246 0.000
M47.2 Other spondylosis with radiculopathy
0.754 0.246 0.000
Y52 Agents primarily affecting the cardiovascular system
0.754 0.246 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.753 0.247 0.000
N75 Diseases of Bartholin's gland
0.753 0.247 0.000
M54.22 Cervicalgia (Cervical region)
0.752 0.248 0.000
M54.8 Other dorsalgia
0.751 0.249 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.751 0.249 0.000
I49.5 Sick sinus syndrome
0.751 0.249 0.000
F29 Unspecified nonorganic psychosis
0.750 0.250 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.749 0.250 0.000
I74 Arterial embolism and thrombosis
0.749 0.251 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.748 0.252 0.000
M10 Gout
0.747 0.253 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
A40 Streptococcal septicaemia
0.746 0.254 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.745 0.254 0.000
B07 Viral warts
0.744 0.256 0.000
Q80-Q89 Other congenital malformations
0.744 0.256 0.000
B02.3 Zoster ocular disease
0.744 0.256 0.000
M50 Cervical disk disorders
0.744 0.256 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.257 0.000
M05 Seropositive rheumatoid arthritis
0.742 0.258 0.000
C25 Malignant neoplasm of pancreas
0.742 0.258 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.742 0.258 0.000
I47.0 Reentry ventricular arrhythmia
0.742 0.258 0.000
M80-M85 Disorders of bone density and structure
0.741 0.259 0.000
N25 Disorders resulting from impaired renal tubular function
0.740 0.260 0.000
I49.4 Other and unspecified premature depolarisation
0.740 0.260 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.739 0.261 0.000
N18.2 Chronic kidney disease, stage 2
0.739 0.261 0.000
N04 Nephrotic syndrome
0.739 0.261 0.000
C71 Malignant neoplasm of brain
0.737 0.263 0.000
X50-X57 Overexertion, travel and privation
0.736 0.264 0.000
B18.2 Chronic viral hepatitis C
0.734 0.266 0.000
W20-W49 Exposure to inanimate mechanical forces
0.734 0.266 0.000
S20 Superficial injury of thorax
0.734 0.266 0.000
M54.9 Dorsalgia, unspecified
0.734 0.266 0.000
R15 Faecal incontinence
0.733 0.267 0.000
M51.2 Other specified intervertebral disk displacement
0.730 0.270 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.729 0.270 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.729 0.271 0.000
T14 Injury of unspecified body region
0.728 0.272 0.000
S27 Injury of other and unspecified intrathoracic organs
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.727 0.273 0.000
I21.9 Acute myocardial infarction, unspecified
0.727 0.273 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
Y46.4 Iminostilbenes
0.726 0.274 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.726 0.274 0.000
N18.4 Chronic kidney disease, stage 4
0.725 0.275 0.000
R23.3 Spontaneous ecchymoses
0.725 0.275 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.725 0.275 0.000
D04.5 Skin of trunk
0.725 0.275 0.000
I71 Aortic aneurysm and dissection
0.724 0.276 0.000
T98 Sequelae of other and unspecified effects of external causes
0.724 0.276 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.722 0.278 0.000
B00 Herpesviral [herpes simplex] infections
0.719 0.281 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.719 0.281 0.000
Y40 Systemic antibiotics
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.715 0.285 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.285 0.000
N75.1 Abscess of Bartholin's gland
0.714 0.286 0.000
M41 Scoliosis
0.714 0.286 0.000
S29 Other and unspecified injuries of thorax
0.714 0.286 0.000
I10-I15 Hypertensive diseases
0.712 0.288 0.000
Q61 Cystic kidney disease
0.712 0.288 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.711 0.289 0.000
B35-B49 Mycoses
0.708 0.292 0.000
T93.2 Sequelae of other fractures of lower limb
0.707 0.292 0.000
X62.9 Unspecified place
0.706 0.294 0.000
N18.1 Chronic kidney disease, stage 1
0.706 0.294 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.705 0.295 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.704 0.295 0.000
N27 Small kidney of unknown cause
0.704 0.295 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.703 0.297 0.000
Y98 Lifestyle-related condition
0.703 0.297 0.000
Y97 Environmental-pollution-related condition
0.703 0.297 0.000
Y96 Work-related condition
0.703 0.297 0.000
I45.3 Trifascicular block
0.703 0.297 0.000
I45.0 Right fascicular block
0.703 0.297 0.000
M54.29 Cervicalgia-Site unspe
0.703 0.297 0.000
M12 Other specific arthropathies
0.702 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.297 0.000
M08 Juvenile arthritis
0.702 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
R29.4 Clicking hip
0.701 0.299 0.000
R29.3 Abnormal posture
0.701 0.299 0.000
R29.2 Abnormal reflex
0.701 0.299 0.000
R29.1 Meningismus
0.701 0.299 0.000
R29.0 Tetany
0.701 0.299 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.700 0.300 0.000
M07 Psoriatic and enteropathic arthropathies
0.699 0.301 0.000
C90.2 Plasmacytoma, extramedullary
0.699 0.301 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.698 0.302 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.698 0.302 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.698 0.302 0.000
S02 Fracture of skull and facial bones
0.698 0.302 0.000
M54.55 Low back pain (Thoracolumbar region)
0.697 0.303 0.000
I25.5 Ischaemic cardiomyopathy
0.697 0.303 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.697 0.303 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.697 0.303 0.000
S22.5 Flail chest
0.696 0.303 0.000
I69 Sequelae of cerebrovascular disease
0.696 0.304 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.694 0.306 0.000
F60.9 Personality disorder, unspecified
0.693 0.307 0.000
C74 Malignant neoplasm of adrenal gland
0.693 0.307 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.693 0.307 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.692 0.308 0.000
D05.7 Other carcinoma in situ of breast
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.690 0.310 0.000
R23.1 Pallor
0.690 0.310 0.000
M54.54 Low back pain-Thoracic
0.690 0.310 0.000
M54.53 Low back pain-Cervicothoracic
0.690 0.310 0.000
M54.52 Low back pain-Cervical
0.690 0.310 0.000
M54.51 Low back pain-Occipit-atl-axl
0.690 0.310 0.000
R25.2 Cramp and spasm
0.689 0.311 0.000
Y84.2 Radiological procedure and radiotherapy
0.689 0.311 0.000
T66-T78 Other and unspecified effects of external causes
0.689 0.311 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.688 0.312 0.000
I44.3 Other and unspecified atrioventricular block
0.688 0.312 0.000
M46.8 Other specified inflammatory spondylopathies
0.687 0.313 0.000
M46.5 Other infective spondylopathies
0.687 0.313 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.687 0.313 0.000
M46.2 Osteomyelitis of vertebra
0.687 0.313 0.000
M46.0 Spinal enthesopathy
0.687 0.313 0.000
I73.8 Other specified peripheral vascular diseases
0.687 0.313 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.687 0.313 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.686 0.314 0.000
T33-T35 Frostbite
0.686 0.314 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.314 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.314 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.685 0.315 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.685 0.315 0.000
M62.8 Other specified disorders of muscle
0.685 0.315 0.000
M06.8 Other specified rheumatoid arthritis
0.684 0.315 0.000
M06.2 Rheumatoid bursitis
0.684 0.315 0.000
M06.1 Adult-onset Still's disease
0.684 0.315 0.000
I25.4 Coronary artery aneurysm
0.684 0.316 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.684 0.316 0.000
N71 Inflammatory disease of uterus, except cervix
0.683 0.317 0.000
I73.0 Raynaud's syndrome
0.681 0.319 0.000
Y54.3 Benzothiadiazine derivatives
0.681 0.319 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.681 0.319 0.000
S22.40 Multiple fractures of ribs (closed)
0.681 0.319 0.000
B99-B99 Other infectious diseases
0.681 0.319 0.000
A49 Bacterial infection of unspecified site
0.680 0.320 0.000
B25-B34 Other viral diseases
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.679 0.321 0.000
B65-B83 Helminthiases
0.678 0.321 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.678 0.322 0.000
C25.0 Head of pancreas
0.678 0.322 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.677 0.322 0.000
I72.3 Aneurysm of iliac artery
0.677 0.323 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.676 0.324 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.676 0.324 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.676 0.324 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.676 0.324 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.676 0.324 0.000
Y84.6 Urinary catheterisation
0.676 0.324 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.324 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.675 0.325 0.000
I49.2 Junctional premature depolarisation
0.674 0.326 0.000
R26 Abnormalities of gait and mobility
0.674 0.326 0.000
M47.9 Spondylosis, unspecified
0.673 0.327 0.000
T79-T79 Certain early complications of trauma
0.673 0.327 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.673 0.327 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.673 0.327 0.000
M47.84 Other spondylosis (Thoracic region)
0.673 0.327 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.673 0.327 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.673 0.327 0.000
I49.8 Other specified cardiac arrhythmias
0.673 0.327 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.672 0.327 0.000
C69.3 Choroid
0.672 0.328 0.000
Y84.8 Other medical procedures
0.672 0.328 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.672 0.328 0.000
V40-V49 Car occupant injured in transport accident
0.671 0.329 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.671 0.329 0.000
B06 Rubella [German measles]
0.671 0.329 0.000
B05 Measles
0.671 0.329 0.000
B01 Varicella [chickenpox]
0.671 0.329 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.671 0.329 0.000
B04 Monkeypox
0.671 0.329 0.000
B03 Smallpox
0.671 0.329 0.000
Q35-Q37 Cleft lip and cleft palate
0.671 0.329 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.671 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.671 0.329 0.000
Y58 Bacterial vaccines
0.671 0.329 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.671 0.329 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.671 0.329 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.671 0.329 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
T92 Sequelae of injuries of upper limb
0.670 0.330 0.000
M89 Other disorders of bone
0.670 0.330 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.666 0.334 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.666 0.334 0.000
M54.14 Radiculopathy (Thoracic region)
0.666 0.334 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.666 0.334 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.666 0.334 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.666 0.334 0.000
X20-X29 Contact with venomous animals and plants
0.666 0.334 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.666 0.334 0.000
M54.59 Low back pain (Site unspecified)
0.665 0.335 0.000
S92 Fracture of foot, except ankle
0.665 0.335 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.665 0.335 0.000
S26 Injury of heart
0.665 0.335 0.000
S25 Injury of blood vessels of thorax
0.665 0.335 0.000
S24 Injury of nerves and spinal cord at thorax level
0.665 0.335 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.665 0.335 0.000
S21 Open wound of thorax
0.665 0.335 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.665 0.335 0.000
M54.35 Sciatica (Thoracolumbar region)
0.664 0.336 0.000
M54.34 Sciatica-Thoracic
0.664 0.336 0.000
M54.33 Sciatica-Cervicothoracic
0.664 0.336 0.000
M54.32 Sciatica-Cervical
0.664 0.336 0.000
M54.31 Sciatica-Occipit-atl-axl
0.664 0.336 0.000
M54.30 Sciatica (Multiple sites in spine)
0.664 0.336 0.000
C69.0 Conjunctiva
0.664 0.336 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.664 0.336 0.000
M60 Myositis
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.663 0.337 0.000
I37.1 Pulmonary valve insufficiency
0.663 0.337 0.000
M54.36 Sciatica (Lumbar region)
0.663 0.337 0.000
I77.5 Necrosis of artery
0.662 0.338 0.000
I77.4 Coeliac artery compression syndrome
0.662 0.338 0.000
I77.3 Arterial fibromuscular dysplasia
0.662 0.338 0.000
I77.2 Rupture of artery
0.662 0.338 0.000
I77.0 Arteriovenous fistula, acquired
0.662 0.338 0.000
C90.0 Multiple myeloma
0.662 0.338 0.000
C21 Malignant neoplasm of anus and anal canal
0.662 0.338 0.000
I20.1 Angina pectoris with documented spasm
0.662 0.338 0.000
D00.0 Lip, oral cavity and pharynx
0.661 0.339 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.661 0.339 0.000
D04.4 Skin of scalp and neck
0.660 0.340 0.000
R47 Speech disturbances, not elsewhere classified
0.660 0.340 0.000
M87 Osteonecrosis
0.658 0.341 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.658 0.342 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.658 0.342 0.000
B17 Other acute viral hepatitis
0.658 0.342 0.000
X78 Intentional self-harm by sharp object
0.657 0.343 0.000
S50-S59 Injuries to the elbow and forearm
0.657 0.343 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.654 0.345 0.000
V20-V29 Motorcycle rider injured in transport accident
0.653 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.346 0.000
M54.37 Sciatica (Lumbosacral region)
0.653 0.347 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.652 0.348 0.000
Q23 Congenital malformations of aortic and mitral valves
0.652 0.348 0.000
I36 Nonrheumatic tricuspid valve disorders
0.652 0.348 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.651 0.349 0.000
C95 Leukaemia of unspecified cell type
0.651 0.349 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.650 0.350 0.000
Y89 Sequelae of other external causes
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.649 0.350 0.000
N04.9 Unspecified
0.648 0.352 0.000
M54.69 Pain in thoracic spine-Site unspe
0.646 0.354 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.646 0.354 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.646 0.354 0.000
M54.66 Pain in thoracic spine-Lumbar
0.646 0.354 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.646 0.354 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.646 0.354 0.000
M54.62 Pain in thoracic spine-Cervical
0.646 0.354 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.646 0.354 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.646 0.354 0.000
Y84.1 Kidney dialysis
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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