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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73177040
log Bayes Factor = 26.055
Chromosome 22   position 46,625,638  (GRCh37) Explore rs73177040 on Ensembl!
Variant rs73177040 is part of Cluster X0098

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.999 0.001 0.000
I95 Hypotension
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Z92.3 Personal history of irradiation
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
I95.9 Hypotension, unspecified
0.995 0.005 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.995 0.005 0.000
J90-J94 Other diseases of pleura
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
K90-K93 Other diseases of the digestive system
0.994 0.006 0.000
D50-D53 Nutritional anaemias
0.993 0.007 0.000
J90 Pleural effusion, not elsewhere classified
0.993 0.007 0.000
Chapter II Neoplasms
0.991 0.009 0.000
D50 Iron deficiency anaemia
0.990 0.010 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.989 0.011 0.000
K55-K64 Other diseases of intestines
0.985 0.015 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.982 0.018 0.000
R10 Abdominal and pelvic pain
0.979 0.021 0.000
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.973 0.027 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.972 0.028 0.000
D50.8 Other iron deficiency anaemias
0.972 0.028 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.970 0.030 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.967 0.033 0.000
I80 Phlebitis and thrombophlebitis
0.966 0.034 0.000
Z93 Artificial opening status
0.966 0.034 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
K92 Other diseases of digestive system
0.958 0.042 0.000
I44 Atrioventricular and left bundle-branch block
0.956 0.044 0.000
N60-N64 Disorders of breast
0.956 0.044 0.000
Chapter VI Diseases of the nervous system
0.954 0.046 0.000
R13 Dysphagia
0.948 0.052 0.000
N17-N19 Renal failure
0.946 0.054 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.946 0.054 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.945 0.055 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.936 0.064 0.000
R10.4 Other and unspecified abdominal pain
0.935 0.065 0.000
Z13 Special screening examination for other diseases and disorders
0.935 0.065 0.000
C20 Malignant neoplasm of rectum
0.932 0.068 0.000
R17 Unspecified jaundice
0.931 0.069 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.929 0.071 0.000
Z90.1 Acquired absence of breast(s)
0.928 0.072 0.000
I95.1 Orthostatic hypotension
0.927 0.073 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.926 0.074 0.000
I44.0 Atrioventricular block, first degree
0.924 0.076 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.924 0.076 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.923 0.077 0.000
R11 Nausea and vomiting
0.920 0.080 0.000
K92.0 Haematemesis
0.918 0.082 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.914 0.086 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.910 0.090 0.000
M47 Spondylosis
0.910 0.090 0.000
D60-D64 Aplastic and other anaemias
0.910 0.090 0.000
I42 Cardiomyopathy
0.909 0.091 0.000
Z51 Other medical care
0.905 0.095 0.000
N30-N39 Other diseases of urinary system
0.899 0.101 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.899 0.101 0.000
K61 Abscess of anal and rectal regions
0.898 0.102 0.000
K57 Diverticular disease of intestine
0.897 0.103 0.000
K62 Other diseases of anus and rectum
0.895 0.105 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.891 0.109 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.888 0.112 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.887 0.113 0.000
K08 Other disorders of teeth and supporting structures
0.887 0.113 0.000
Z43 Attention to artificial openings
0.887 0.113 0.000
Z49 Care involving dialysis
0.884 0.116 0.000
M47.9 Spondylosis, unspecified
0.883 0.117 0.000
Z13.9 Special screening examination, unspecified
0.881 0.119 0.000
Z90.0 Acquired absence of part of head and neck
0.877 0.123 0.000
N62 Hypertrophy of breast
0.877 0.123 0.000
Z93.2 Ileostomy status
0.870 0.130 0.000
M05-M14 Inflammatory polyarthropathies
0.870 0.130 0.000
I73 Other peripheral vascular diseases
0.867 0.133 0.000
M46 Other inflammatory spondylopathies
0.866 0.134 0.000
M80-M85 Disorders of bone density and structure
0.862 0.138 0.000
C18 Malignant neoplasm of colon
0.861 0.139 0.000
Z03.1 Observation for suspected malignant neoplasm
0.860 0.140 0.000
G40-G47 Episodic and paroxysmal disorders
0.860 0.140 0.000
D64 Other anaemias
0.859 0.141 0.000
J93 Pneumothorax
0.858 0.141 0.000
I42.0 Dilated cardiomyopathy
0.858 0.142 0.000
R80 Isolated proteinuria
0.857 0.143 0.000
Z51.5 Palliative care
0.857 0.143 0.000
K92.1 Melaena
0.856 0.144 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.855 0.145 0.000
N18 Chronic renal failure
0.853 0.147 0.000
I44.7 Left bundle-branch block, unspecified
0.852 0.148 0.000
N32 Other disorders of bladder
0.851 0.149 0.000
N10-N16 Renal tubulo-interstitial diseases
0.851 0.149 0.000
Z85 Personal history of malignant neoplasm
0.849 0.151 0.000
Z93.3 Colostomy status
0.848 0.152 0.000
K01 Embedded and impacted teeth
0.844 0.156 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.840 0.160 0.000
K62.1 Rectal polyp
0.838 0.162 0.000
R18 Ascites
0.838 0.162 0.000
Z42 Follow-up care involving plastic surgery
0.838 0.162 0.000
K61.0 Anal abscess
0.836 0.164 0.000
K60 Fissure and fistula of anal and rectal regions
0.835 0.165 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.833 0.167 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.832 0.168 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.832 0.168 0.000
N64 Other disorders of breast
0.831 0.169 0.000
N17 Acute renal failure
0.831 0.169 0.000
Z52 Donors of organs and tissues
0.827 0.172 0.000
M50-M54 Other dorsopathies
0.827 0.173 0.000
M20-M25 Other joint disorders
0.825 0.175 0.000
I35 Nonrheumatic aortic valve disorders
0.824 0.176 0.000
R82 Other abnormal findings in urine
0.824 0.176 0.000
D64.9 Anaemia, unspecified
0.823 0.177 0.000
Chapter XX External causes of morbidity and mortality
0.821 0.179 0.000
K11 Diseases of salivary glands
0.819 0.181 0.000
K63 Other diseases of intestine
0.819 0.181 0.000
Z86 Personal history of certain other diseases
0.818 0.182 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
D50.9 Iron deficiency anaemia, unspecified
0.816 0.184 0.000
K86 Other diseases of pancreas
0.816 0.184 0.000
Z83 Family history of other specific disorders
0.813 0.186 0.000
G30-G32 Other degenerative diseases of the nervous system
0.812 0.188 0.000
R15 Faecal incontinence
0.810 0.190 0.000
M40-M43 Deforming dorsopathies
0.809 0.191 0.000
J09-J18 Influenza and pneumonia
0.809 0.191 0.000
Z49.1 Extracorporeal dialysis
0.809 0.191 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.808 0.192 0.000
C15 Malignant neoplasm of oesophagus
0.807 0.193 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.807 0.193 0.000
K62.9 Disease of anus and rectum, unspecified
0.806 0.194 0.000
R10.0 Acute abdomen
0.805 0.195 0.000
R06 Abnormalities of breathing
0.804 0.196 0.000
R10.2 Pelvic and perineal pain
0.804 0.196 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.802 0.198 0.000
J00-J06 Acute upper respiratory infections
0.802 0.198 0.000
I74 Arterial embolism and thrombosis
0.800 0.200 0.000
Z92.8 Personal history of other medical treatment
0.799 0.200 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.799 0.201 0.000
J91 Pleural effusion in conditions classified elsewhere
0.798 0.202 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.798 0.202 0.000
K91.4 Colostomy and enterostomy malfunction
0.798 0.202 0.000
C83.3 Large cell (diffuse)
0.798 0.202 0.000
I73.9 Peripheral vascular disease, unspecified
0.796 0.204 0.000
D75 Other diseases of blood and blood-forming organs
0.796 0.204 0.000
Z04 Examination and observation for other reasons
0.793 0.207 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.793 0.207 0.000
D00-D09 In situ neoplasms
0.793 0.207 0.000
R04 Haemorrhage from respiratory passages
0.792 0.208 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.791 0.209 0.000
N61 Inflammatory disorders of breast
0.790 0.210 0.000
I77 Other disorders of arteries and arterioles
0.789 0.210 0.000
D80-D89 Certain disorders involving the immune mechanism
0.788 0.212 0.000
Z41 Procedures for purposes other than remedying health state
0.787 0.213 0.000
N32.8 Other specified disorders of bladder
0.785 0.215 0.000
K91.3 Postoperative intestinal obstruction
0.784 0.216 0.000
K62.8 Other specified diseases of anus and rectum
0.784 0.216 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.784 0.216 0.000
Chapter VIII Diseases of the ear and mastoid process
0.783 0.217 0.000
K65-K67 Diseases of peritoneum
0.783 0.217 0.000
N39 Other disorders of urinary system
0.782 0.218 0.000
N20-N23 Urolithiasis
0.781 0.219 0.000
Z45 Adjustment and management of implanted device
0.780 0.220 0.000
R05 Cough
0.780 0.220 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.779 0.221 0.000
R47-R49 Symptoms and signs involving speech and voice
0.779 0.221 0.000
I38 Endocarditis, valve unspecified
0.778 0.222 0.000
Z46 Fitting and adjustment of other devices
0.777 0.223 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.777 0.223 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.776 0.224 0.000
G40 Epilepsy
0.776 0.224 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.775 0.225 0.000
C18.9 Colon, unspecified
0.775 0.225 0.000
R07 Pain in throat and chest
0.775 0.225 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.774 0.226 0.000
K09 Cysts of oral region, not elsewhere classified
0.774 0.226 0.000
Z89 Acquired absence of limb
0.772 0.228 0.000
Z98 Other postsurgical states
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.771 0.229 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.770 0.230 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.767 0.233 0.000
K14 Diseases of tongue
0.766 0.234 0.000
M10 Gout
0.766 0.234 0.000
S00-S09 Injuries to the head
0.765 0.235 0.000
I05-I09 Chronic rheumatic heart diseases
0.764 0.236 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.764 0.236 0.000
Z02 Examination and encounter for administrative purposes
0.764 0.236 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.764 0.236 0.000
K82 Other diseases of gallbladder
0.764 0.236 0.000
N13 Obstructive and reflux uropathy
0.762 0.238 0.000
C16 Malignant neoplasm of stomach
0.761 0.239 0.000
Chapter I Certain infectious and parasitic diseases
0.761 0.239 0.000
J93.9 Pneumothorax, unspecified
0.761 0.239 0.000
Z86.7 Personal history of diseases of the circulatory system
0.760 0.240 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.759 0.241 0.000
N39.0 Urinary tract infection, site not specified
0.758 0.242 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.757 0.243 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.757 0.243 0.000
C77.2 Intra-abdominal lymph nodes
0.757 0.243 0.000
M86-M90 Other osteopathies
0.755 0.244 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.755 0.245 0.000
K70-K77 Diseases of liver
0.754 0.246 0.000
R10.3 Pain localised to other parts of lower abdomen
0.754 0.246 0.000
J95-J99 Other diseases of the respiratory system
0.754 0.246 0.000
K85 Acute pancreatitis
0.753 0.247 0.000
K12 Stomatitis and related lesions
0.752 0.248 0.000
J20-J22 Other acute lower respiratory infections
0.752 0.248 0.000
J94 Other pleural conditions
0.751 0.249 0.000
K01.1 Impacted teeth
0.749 0.251 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.748 0.252 0.000
Z90.3 Acquired absence of part of stomach
0.748 0.252 0.000
Z43.2 Attention to ileostomy
0.748 0.252 0.000
N17.9 Acute renal failure, unspecified
0.748 0.252 0.000
N25-N29 Other disorders of kidney and ureter
0.747 0.253 0.000
K86.1 Other chronic pancreatitis
0.747 0.253 0.000
M70-M79 Other soft tissue disorders
0.746 0.254 0.000
M91-M94 Chondropathies
0.745 0.254 0.000
N18.5 Chronic kidney disease, stage 5
0.745 0.255 0.000
C77.1 Intrathoracic lymph nodes
0.742 0.258 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.742 0.258 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.741 0.259 0.000
M80 Osteoporosis with pathological fracture
0.741 0.259 0.000
D73 Diseases of spleen
0.740 0.260 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.740 0.260 0.000
I84 Haemorrhoids
0.740 0.260 0.000
R00 Abnormalities of heart beat
0.740 0.260 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.740 0.260 0.000
A30-A49 Other bacterial diseases
0.739 0.261 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.737 0.263 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.737 0.263 0.000
M00-M03 Infectious arthropathies
0.737 0.263 0.000
G43 Migraine
0.736 0.264 0.000
Z13.1 Special screening examination for diabetes mellitus
0.736 0.264 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.734 0.266 0.000
Z83.7 Family history of diseases of the digestive system
0.734 0.266 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.733 0.266 0.000
R01 Cardiac murmurs and other cardiac sounds
0.732 0.268 0.000
C18.0 Caecum
0.732 0.268 0.000
K08.3 Retained dental root
0.732 0.268 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.732 0.268 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.730 0.270 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.270 0.000
G90-G99 Other disorders of the nervous system
0.730 0.270 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.729 0.270 0.000
R07.4 Chest pain, unspecified
0.729 0.271 0.000
Z43.5 Attention to cyctostomy
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.728 0.272 0.000
M47.2 Other spondylosis with radiculopathy
0.726 0.274 0.000
K60.2 Anal fissure, unspecified
0.726 0.274 0.000
Z93.6 Other artificial openings of urinary tract status
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
N18.9 Chronic renal failure, unspecified
0.723 0.277 0.000
Z51.1 Chemotherapy session for neoplasm
0.722 0.278 0.000
Z97 Presence of other devices
0.722 0.278 0.000
K63.8 Other specified diseases of intestine
0.720 0.280 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.720 0.280 0.000
Q60-Q64 Congenital malformations of the urinary system
0.719 0.281 0.000
A41 Other septicaemia
0.719 0.281 0.000
C71 Malignant neoplasm of brain
0.718 0.281 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
Z92.0 Personal history of contraception
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
G30 Alzheimer's disease
0.716 0.283 0.000
Z04.8 Examination and observation for other specified reasons
0.716 0.284 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.284 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.716 0.284 0.000
I99 Other and unspecified disorders of circulatory system
0.716 0.284 0.000
Z93.0 Tracheostomy status
0.716 0.284 0.000
I95.8 Other hypotension
0.715 0.284 0.000
I95.2 Hypotension due to drugs
0.715 0.284 0.000
I95.0 Idiopathic hypotension
0.715 0.284 0.000
K10 Other diseases of jaws
0.715 0.285 0.000
N19 Unspecified renal failure
0.715 0.285 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.714 0.286 0.000
R04.2 Haemoptysis
0.713 0.287 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.712 0.287 0.000
C91 Lymphoid leukaemia
0.712 0.288 0.000
M65-M68 Disorders of synovium and tendon
0.712 0.288 0.000
D53 Other nutritional anaemias
0.712 0.288 0.000
D52 Folate deficiency anaemia
0.712 0.288 0.000
N00-N08 Glomerular diseases
0.711 0.288 0.000
Z52.4 Kidney donor
0.711 0.289 0.000
I30 Acute pericarditis
0.711 0.289 0.000
Z51.0 Radiotherapy session
0.711 0.289 0.000
N32.9 Bladder disorder, unspecified
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.710 0.290 0.000
R30-R39 Symptoms and signs involving the urinary system
0.710 0.290 0.000
Z51.9 Medical care, unspecified
0.710 0.290 0.000
R82.9 Other and unspecified abnormal finding in urine
0.710 0.290 0.000
G20-G26 Extrapyramidal and movement disorders
0.710 0.290 0.000
D50.1 Sideropenic dysphagia
0.709 0.290 0.000
Z54 Convalescence
0.709 0.291 0.000
Z44 Fitting and adjustment of external prosthetic device
0.709 0.291 0.000
K02 Dental caries
0.709 0.291 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.709 0.291 0.000
I44.2 Atrioventricular block, complete
0.709 0.291 0.000
M47.1 Other spondylosis with myelopathy
0.709 0.291 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.708 0.292 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.708 0.292 0.000
C60-C63 Malignant neoplasms of male genital organs
0.706 0.294 0.000
R10.1 Pain localised to upper abdomen
0.706 0.294 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.706 0.294 0.000
I31 Other diseases of pericardium
0.706 0.294 0.000
A41.9 Septicaemia, unspecified
0.706 0.294 0.000
N36 Other disorders of urethra
0.704 0.296 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.704 0.296 0.000
I51 Complications and ill-defined descriptions of heart disease
0.703 0.297 0.000
M50 Cervical disk disorders
0.703 0.297 0.000
N13.3 Other and unspecified hydronephrosis
0.703 0.297 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.703 0.297 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.702 0.298 0.000
H90-H95 Other disorders of ear
0.702 0.298 0.000
C18.3 Hepatic flexure
0.702 0.298 0.000
C25 Malignant neoplasm of pancreas
0.702 0.298 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.701 0.299 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.701 0.299 0.000
C21 Malignant neoplasm of anus and anal canal
0.701 0.299 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
C23 Malignant neoplasm of gallbladder
0.701 0.299 0.000
K03 Other diseases of hard tissues of teeth
0.699 0.301 0.000
K00 Disorders of tooth development and eruption
0.699 0.301 0.000
Z93.1 Gastrostomy status
0.698 0.302 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.698 0.302 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.302 0.000
I48 Atrial fibrillation and flutter
0.698 0.302 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.302 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.302 0.000
I40 Acute myocarditis
0.698 0.302 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.698 0.302 0.000
I36 Nonrheumatic tricuspid valve disorders
0.698 0.302 0.000
I33 Acute and subacute endocarditis
0.698 0.302 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.302 0.000
Q00-Q07 Congenital malformations of the nervous system
0.697 0.303 0.000
I88 Nonspecific lymphadenitis
0.697 0.303 0.000
I87 Other disorders of veins
0.697 0.303 0.000
I86 Varicose veins of other sites
0.697 0.303 0.000
I81 Portal vein thrombosis
0.697 0.303 0.000
N63 Unspecified lump in breast
0.697 0.303 0.000
N64.9 Disorder of breast, unspecified
0.696 0.304 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.695 0.305 0.000
K91.5 Postcholecystectomy syndrome
0.695 0.305 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.695 0.305 0.000
K91.1 Postgastric surgery syndromes
0.695 0.305 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.695 0.305 0.000
J81 Pulmonary oedema
0.695 0.305 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.694 0.306 0.000
D72 Other disorders of white blood cells
0.694 0.306 0.000
M23 Internal derangement of knee
0.694 0.306 0.000
Z45.2 Adjustment and management of vascular access device
0.694 0.306 0.000
C85.1 B-cell lymphoma, unspecified
0.694 0.306 0.000
Z10 Routine general health check-up of defined subpopulation
0.694 0.306 0.000
C18.6 Descending colon
0.692 0.307 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.692 0.307 0.000
Z93.9 Artificial opening status, unspecified
0.692 0.308 0.000
Z93.8 Other artificial opening status
0.692 0.308 0.000
Z93.5 Cystostomy status
0.692 0.308 0.000
M10.9 Gout, unspecified
0.692 0.308 0.000
Z99.2 Dependence on renal dialysis
0.692 0.308 0.000
K60.5 Anorectal fistula
0.691 0.309 0.000
O00-O08 Pregnancy with abortive outcome
0.691 0.309 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.691 0.309 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.690 0.310 0.000
M49 Spondylopathies in diseases classified elsewhere
0.689 0.311 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.689 0.311 0.000
Z90.2 Acquired absence of lung [part of]
0.688 0.311 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.688 0.312 0.000
I77.1 Stricture of artery
0.688 0.312 0.000
K92.8 Other specified diseases of digestive system
0.687 0.313 0.000
N32.1 Vesicointestinal fistula
0.687 0.313 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.686 0.314 0.000
J03 Acute tonsillitis
0.686 0.314 0.000
I44.6 Other and unspecified fascicular block
0.685 0.314 0.000
I44.5 Left posterior fascicular block
0.685 0.314 0.000
I44.4 Left anterior fascicular block
0.685 0.314 0.000
I44.3 Other and unspecified atrioventricular block
0.685 0.314 0.000
S10-S19 Injuries to the neck
0.684 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
R06.8 Other and unspecified abnormalities of breathing
0.683 0.317 0.000
K59 Other functional intestinal disorders
0.683 0.317 0.000
C77.8 Lymph nodes of multiple regions
0.683 0.317 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.683 0.317 0.000
D70 Agranulocytosis
0.682 0.317 0.000
D75.2 Essential thrombocytosis
0.682 0.318 0.000
J60-J70 Lung diseases due to external agents
0.682 0.318 0.000
N64.1 Fat necrosis of breast
0.681 0.319 0.000
Z53.0 Procedure not carried out because of contraindication
0.681 0.319 0.000
Z03.3 Observation for suspected nervous system disorder
0.681 0.319 0.000
K92.9 Disease of digestive system, unspecified
0.680 0.319 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.680 0.320 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.679 0.321 0.000
I72 Other aneurysm
0.678 0.321 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.678 0.322 0.000
C78.0 Secondary malignant neoplasm of lung
0.678 0.322 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.678 0.322 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.678 0.322 0.000
N20 Calculus of kidney and ureter
0.678 0.322 0.000
R81 Glycosuria
0.677 0.323 0.000
I42.9 Cardiomyopathy, unspecified
0.677 0.323 0.000
I35.1 Aortic (valve) insufficiency
0.676 0.324 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.675 0.325 0.000
M24 Other specific joint derangements
0.675 0.325 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.675 0.325 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.675 0.325 0.000
I70 Atherosclerosis
0.673 0.326 0.000
G40.9 Epilepsy, unspecified
0.673 0.327 0.000
I84.2 Internal haemorrhoids without complication
0.673 0.327 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.673 0.327 0.000
Z43.3 Attention to colostomy
0.673 0.327 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.672 0.328 0.000
R31 Unspecified haematuria
0.672 0.328 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.671 0.329 0.000
C95 Leukaemia of unspecified cell type
0.671 0.329 0.000
C94 Other leukaemias of specified cell type
0.671 0.329 0.000
C93 Monocytic leukaemia
0.671 0.329 0.000
C88 Malignant immunoproliferative diseases
0.671 0.329 0.000
C86 Other specified types of T/NK-cell lymphoma
0.671 0.329 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.671 0.329 0.000
C81 Hodgkin's disease
0.671 0.329 0.000
Z90.8 Acquired absence of other organs
0.671 0.329 0.000
K13 Other diseases of lip and oral mucosa
0.671 0.329 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.670 0.330 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.670 0.330 0.000
Z13.5 Special screening examination for eye and ear disorders
0.670 0.330 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.670 0.330 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.670 0.330 0.000
Z13.2 Special screening examination for nutritional disorders
0.670 0.330 0.000
K65 Peritonitis
0.670 0.330 0.000
D05 Carcinoma in situ of breast
0.670 0.330 0.000
I73.0 Raynaud's syndrome
0.668 0.332 0.000
M05 Seropositive rheumatoid arthritis
0.668 0.332 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.668 0.332 0.000
I82 Other venous embolism and thrombosis
0.668 0.332 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.668 0.332 0.000
Z85.6 Personal history of leukaemia
0.667 0.333 0.000
Chapter V Mental and behavioural disorders
0.666 0.334 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.666 0.334 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.665 0.335 0.000
Z40 Prophylactic surgery
0.663 0.337 0.000
Z03.8 Observation for other suspected diseases and conditions
0.663 0.337 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.662 0.338 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.662 0.338 0.000
N40-N51 Diseases of male genital organs
0.661 0.339 0.000
D68 Other coagulation defects
0.661 0.339 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.661 0.339 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.660 0.340 0.000
I44.1 Atrioventricular block, second degree
0.660 0.340 0.000
M11 Other crystal arthropathies
0.659 0.340 0.000
K35-K38 Diseases of appendix
0.658 0.342 0.000
C15.5 Lower third of oesophagus
0.657 0.343 0.000
M51 Other intervertebral disk disorders
0.656 0.344 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.656 0.344 0.000
D74 Methaemoglobinaemia
0.656 0.344 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.656 0.344 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.656 0.344 0.000
C18.5 Splenic flexure
0.655 0.344 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.655 0.344 0.000
Z35 Supervision of high-risk pregnancy
0.655 0.345 0.000
Z94 Transplanted organ and tissue status
0.654 0.346 0.000
K07 Dentofacial anomalies [including malocclusion]
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.654 0.346 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.653 0.347 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.652 0.347 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.652 0.348 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.652 0.348 0.000
L20-L30 Dermatitis and eczema
0.652 0.348 0.000
I42.8 Other cardiomyopathies
0.651 0.348 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.651 0.348 0.000
I42.6 Alcoholic cardiomyopathy
0.651 0.348 0.000
I42.5 Other restrictive cardiomyopathy
0.651 0.348 0.000
I42.4 Endocardial fibroelastosis
0.651 0.348 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.651 0.348 0.000
I42.2 Other hypertrophic cardiomyopathy
0.651 0.348 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.651 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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