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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73210044
log Bayes Factor = 15.2486
Chromosome 8   position 13,392,360  (GRCh37) Explore rs73210044 on Ensembl!
Variant rs73210044 is part of Cluster X0182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
R07.4 Chest pain, unspecified
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
R07 Pain in throat and chest
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.995 0.005 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Z93 Artificial opening status
0.988 0.012 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
E11.9 Without complications
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
E10 Insulin-dependent diabetes mellitus
0.980 0.020 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.970 0.030 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.969 0.031 0.000
Z93.2 Ileostomy status
0.965 0.035 0.000
I60-I69 Cerebrovascular diseases
0.965 0.035 0.000
Z90.5 Acquired absence of kidney
0.965 0.035 0.000
E10.9 Without complications
0.961 0.039 0.000
A00-A09 Intestinal infectious diseases
0.961 0.039 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.957 0.043 0.000
I05-I09 Chronic rheumatic heart diseases
0.956 0.044 0.000
Chapter XIV Diseases of the genitourinary system
0.956 0.044 0.000
Z87 Personal history of other diseases and conditions
0.955 0.045 0.000
Z04 Examination and observation for other reasons
0.954 0.046 0.000
Chapter VII Diseases of the eye and adnexa
0.950 0.050 0.000
N17-N19 Renal failure
0.943 0.057 0.000
Y43 Primarily systemic agents
0.942 0.058 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.941 0.059 0.000
I35 Nonrheumatic aortic valve disorders
0.938 0.062 0.000
R42 Dizziness and giddiness
0.934 0.066 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.929 0.071 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.928 0.072 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.928 0.072 0.000
B35-B49 Mycoses
0.926 0.074 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.926 0.074 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.925 0.075 0.000
R03.1 Nonspecific low blood-pressure reading
0.923 0.077 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.923 0.077 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.917 0.083 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.915 0.085 0.000
N19 Unspecified renal failure
0.913 0.087 0.000
R04 Haemorrhage from respiratory passages
0.913 0.087 0.000
Z93.3 Colostomy status
0.913 0.087 0.000
Z03.4 Observation for suspected myocardial infarction
0.912 0.088 0.000
I63 Cerebral infarction
0.905 0.095 0.000
H50 Other strabismus
0.903 0.097 0.000
Y43.3 Other antineoplastic drugs
0.901 0.099 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.898 0.102 0.000
I34 Nonrheumatic mitral valve disorders
0.898 0.102 0.000
R07.2 Precordial pain
0.895 0.105 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.894 0.106 0.000
I10-I15 Hypertensive diseases
0.890 0.110 0.000
I74 Arterial embolism and thrombosis
0.890 0.110 0.000
Z04.3 Examination and observation following other accident
0.889 0.111 0.000
Chapter V Mental and behavioural disorders
0.886 0.114 0.000
Chapter X Diseases of the respiratory system
0.881 0.119 0.000
I77 Other disorders of arteries and arterioles
0.879 0.121 0.000
N18 Chronic renal failure
0.879 0.121 0.000
I95 Hypotension
0.878 0.122 0.000
I63.9 Cerebral infarction, unspecified
0.877 0.123 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.874 0.126 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.873 0.127 0.000
I45 Other conduction disorders
0.868 0.132 0.000
A04 Other bacterial intestinal infections
0.867 0.133 0.000
I34.0 Mitral (valve) insufficiency
0.866 0.134 0.000
I05 Rheumatic mitral valve diseases
0.866 0.134 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.864 0.136 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.861 0.139 0.000
E20-E35 Disorders of other endocrine glands
0.860 0.140 0.000
E11.2 With renal complications
0.859 0.141 0.000
L60-L75 Disorders of skin appendages
0.859 0.141 0.000
H25-H28 Disorders of lens
0.857 0.143 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.857 0.143 0.000
E11.1 With ketoacidosis
0.857 0.143 0.000
Q21 Congenital malformations of cardiac septa
0.856 0.144 0.000
Z90.8 Acquired absence of other organs
0.856 0.144 0.000
H50.1 Divergent concomitant strabismus
0.856 0.144 0.000
Z90.2 Acquired absence of lung [part of]
0.850 0.150 0.000
Z90.3 Acquired absence of part of stomach
0.849 0.151 0.000
J30-J39 Other diseases of upper respiratory tract
0.847 0.153 0.000
I95.1 Orthostatic hypotension
0.845 0.155 0.000
Y42.7 Androgens and anabolic congeners
0.841 0.159 0.000
Z04.1 Examination and observation following transport accident
0.840 0.160 0.000
B37 Candidiasis
0.836 0.164 0.000
I77.1 Stricture of artery
0.836 0.164 0.000
X60-X84 Intentional self-harm
0.833 0.167 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.830 0.170 0.000
I35.0 Aortic (valve) stenosis
0.830 0.170 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.830 0.170 0.000
E10.8 With unspecified complications
0.821 0.179 0.000
J33 Nasal polyp
0.820 0.180 0.000
N18.3 Chronic kidney disease, stage 3
0.819 0.181 0.000
Z90.1 Acquired absence of breast(s)
0.819 0.181 0.000
N18.9 Chronic renal failure, unspecified
0.818 0.182 0.000
Z04.9 Examination and observation for unspecified reason
0.815 0.185 0.000
N60-N64 Disorders of breast
0.812 0.188 0.000
A04.8 Other specified bacterial intestinal infections
0.810 0.190 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.810 0.190 0.000
V20-V29 Motorcycle rider injured in transport accident
0.810 0.190 0.000
L20-L30 Dermatitis and eczema
0.810 0.190 0.000
I49 Other cardiac arrhythmias
0.810 0.190 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.807 0.193 0.000
I07 Rheumatic tricuspid valve diseases
0.805 0.195 0.000
I67 Other cerebrovascular diseases
0.804 0.196 0.000
I70 Atherosclerosis
0.802 0.198 0.000
I35.1 Aortic (valve) insufficiency
0.801 0.199 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.800 0.200 0.000
R04.2 Haemoptysis
0.799 0.201 0.000
I71 Aortic aneurysm and dissection
0.797 0.203 0.000
Z03.3 Observation for suspected nervous system disorder
0.796 0.204 0.000
I38 Endocarditis, valve unspecified
0.795 0.205 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.795 0.205 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.793 0.207 0.000
Z98 Other postsurgical states
0.792 0.208 0.000
I47 Paroxysmal tachycardia
0.791 0.209 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.791 0.209 0.000
Z13 Special screening examination for other diseases and disorders
0.791 0.209 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.790 0.210 0.000
I08 Multiple valve diseases
0.789 0.211 0.000
F30-F39 Mood [affective] disorders
0.789 0.211 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.788 0.212 0.000
A80-A89 Viral infections of the central nervous system
0.787 0.213 0.000
E11.0 With coma
0.787 0.213 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.787 0.213 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.785 0.215 0.000
R05 Cough
0.781 0.219 0.000
Q21.1 Atrial septal defect
0.780 0.220 0.000
Y52 Agents primarily affecting the cardiovascular system
0.780 0.220 0.000
Chapter VIII Diseases of the ear and mastoid process
0.780 0.220 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.775 0.225 0.000
J33.0 Polyp of nasal cavity
0.775 0.225 0.000
E70-E90 Metabolic disorders
0.774 0.226 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.774 0.226 0.000
R04.0 Epistaxis
0.773 0.227 0.000
B37.0 Candidal stomatitis
0.771 0.229 0.000
J39 Other diseases of upper respiratory tract
0.769 0.231 0.000
H25 Senile cataract
0.769 0.231 0.000
Z00.0 General medical examination
0.768 0.232 0.000
A30-A49 Other bacterial diseases
0.768 0.232 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
I12 Hypertensive renal disease
0.766 0.234 0.000
E11.3 With ophthalmic complications
0.766 0.234 0.000
I73 Other peripheral vascular diseases
0.765 0.235 0.000
Q23 Congenital malformations of aortic and mitral valves
0.763 0.236 0.000
Q50-Q56 Congenital malformations of genital organs
0.763 0.237 0.000
I05.9 Mitral valve disease, unspecified
0.760 0.240 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.760 0.240 0.000
E13 Other specified diabetes mellitus
0.758 0.242 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.758 0.242 0.000
R45 Symptoms and signs involving emotional state
0.758 0.242 0.000
Z93.5 Cystostomy status
0.758 0.242 0.000
J33.9 Nasal polyp, unspecified
0.757 0.243 0.000
E10.5 With peripheral circulatory complications
0.756 0.244 0.000
N10-N16 Renal tubulo-interstitial diseases
0.756 0.244 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.753 0.247 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.752 0.248 0.000
H40-H42 Glaucoma
0.752 0.248 0.000
R00 Abnormalities of heart beat
0.752 0.248 0.000
Z97 Presence of other devices
0.751 0.249 0.000
H50.9 Strabismus, unspecified
0.751 0.249 0.000
N73 Other female pelvic inflammatory diseases
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.751 0.249 0.000
R40 Somnolence, stupor and coma
0.751 0.249 0.000
W50-W64 Exposure to animate mechanical forces
0.749 0.251 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.749 0.251 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.748 0.252 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.748 0.252 0.000
B44 Aspergillosis
0.748 0.252 0.000
N70 Salpingitis and oophoritis
0.747 0.253 0.000
I50 Heart failure
0.746 0.254 0.000
E65-E68 Obesity and other hyperalimentation
0.744 0.256 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.740 0.260 0.000
S00-S09 Injuries to the head
0.739 0.261 0.000
I62 Other nontraumatic intracranial haemorrhage
0.739 0.261 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.737 0.262 0.000
V40-V49 Car occupant injured in transport accident
0.736 0.264 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.736 0.264 0.000
Y42.5 Other oestrogens and progestogens
0.736 0.264 0.000
I74.5 Embolism and thrombosis of iliac artery
0.735 0.265 0.000
Z13.9 Special screening examination, unspecified
0.734 0.266 0.000
S31 Open wound of abdomen, lower back and pelvis
0.734 0.266 0.000
H52 Disorders of refraction and accommodation
0.734 0.266 0.000
Z93.0 Tracheostomy status
0.733 0.266 0.000
I36 Nonrheumatic tricuspid valve disorders
0.733 0.267 0.000
L72.0 Epidermal cyst
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.732 0.268 0.000
T66-T78 Other and unspecified effects of external causes
0.732 0.268 0.000
H50.2 Vertical strabismus
0.730 0.270 0.000
I45.1 Other and unspecified right bundle-branch block
0.727 0.273 0.000
J60-J70 Lung diseases due to external agents
0.727 0.273 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.726 0.274 0.000
H10-H13 Disorders of conjunctiva
0.726 0.274 0.000
I60 Subarachnoid haemorrhage
0.725 0.275 0.000
R09.2 Respiratory arrest
0.725 0.275 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.725 0.275 0.000
H25.0 Senile incipient cataract
0.725 0.275 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.724 0.276 0.000
Z93.6 Other artificial openings of urinary tract status
0.723 0.276 0.000
Q27 Other congenital malformations of peripheral vascular system
0.723 0.277 0.000
H49 Paralytic strabismus
0.722 0.278 0.000
I10 Essential (primary) hypertension
0.721 0.279 0.000
S60-S69 Injuries to the wrist and hand
0.720 0.280 0.000
Z89 Acquired absence of limb
0.720 0.280 0.000
B49 Unspecified mycosis
0.718 0.282 0.000
I45.6 Preexcitation syndrome
0.718 0.282 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
I72 Other aneurysm
0.716 0.283 0.000
L71 Rosacea
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.715 0.285 0.000
R09.3 Abnormal sputum
0.715 0.285 0.000
R00.0 Tachycardia, unspecified
0.715 0.285 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.714 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
Q60-Q64 Congenital malformations of the urinary system
0.714 0.286 0.000
E11.8 With unspecified complications
0.713 0.286 0.000
E11.7 With multiple complications
0.713 0.286 0.000
E11.6 With other specified complications
0.713 0.286 0.000
Z90.0 Acquired absence of part of head and neck
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
Y43.1 Antineoplastic antimetabolites
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.287 0.000
Y10-Y34 Event of undetermined intent
0.712 0.287 0.000
Y00-Y09 Assault
0.712 0.287 0.000
X85-X99 Assault
0.712 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.287 0.000
X50-X57 Overexertion, travel and privation
0.712 0.287 0.000
X30-X39 Exposure to forces of nature
0.712 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.287 0.000
W75-W84 Other accidental threats to breathing
0.712 0.287 0.000
W65-W74 Accidental drowning and submersion
0.712 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.287 0.000
V90-V94 Water transport accidents
0.712 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.287 0.000
S10-S19 Injuries to the neck
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
R79 Other abnormal findings of blood chemistry
0.712 0.288 0.000
I35.8 Other aortic valve disorders
0.712 0.288 0.000
E50-E64 Other nutritional deficiencies
0.712 0.288 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.710 0.289 0.000
I49.9 Cardiac arrhythmia, unspecified
0.710 0.290 0.000
Y43.4 Immunosuppressive agents
0.708 0.292 0.000
Z93.9 Artificial opening status, unspecified
0.708 0.292 0.000
Z93.8 Other artificial opening status
0.708 0.292 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.708 0.292 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.292 0.000
L73 Other follicular disorders
0.708 0.292 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
N89 Other noninflammatory disorders of vagina
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.705 0.294 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.704 0.296 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
R07.1 Chest pain on breathing
0.704 0.296 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.704 0.296 0.000
E10.1 With ketoacidosis
0.704 0.296 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.703 0.297 0.000
B35 Dermatophytosis
0.703 0.297 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.702 0.297 0.000
E10.7 With multiple complications
0.702 0.298 0.000
E10.6 With other specified complications
0.702 0.298 0.000
E10.4 With neurological complications
0.702 0.298 0.000
E10.2 With renal complications
0.702 0.298 0.000
E10.0 With coma
0.702 0.298 0.000
N94.6 Dysmenorrhoea, unspecified
0.702 0.298 0.000
I27 Other pulmonary heart diseases
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
Q21.0 Ventricular septal defect
0.701 0.299 0.000
Z10 Routine general health check-up of defined subpopulation
0.699 0.301 0.000
Q80-Q89 Other congenital malformations
0.699 0.301 0.000
I99 Other and unspecified disorders of circulatory system
0.698 0.302 0.000
I12.0 Hypertensive renal disease with renal failure
0.698 0.302 0.000
L50-L54 Urticaria and erythema
0.698 0.302 0.000
Z83 Family history of other specific disorders
0.697 0.303 0.000
I07.1 Tricuspid insufficiency
0.697 0.303 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.697 0.303 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.696 0.304 0.000
I52 Other heart disorders in diseases classified elsewhere
0.696 0.304 0.000
I48 Atrial fibrillation and flutter
0.696 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.696 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.696 0.304 0.000
I40 Acute myocarditis
0.696 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.696 0.304 0.000
I37 Pulmonary valve disorders
0.696 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.696 0.304 0.000
Q35-Q37 Cleft lip and cleft palate
0.696 0.304 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.696 0.304 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.696 0.304 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.696 0.304 0.000
Z95.4 Presence of other heart-valve replacement
0.695 0.305 0.000
R47-R49 Symptoms and signs involving speech and voice
0.695 0.305 0.000
B37.3 Candidiasis of vulva and vagina
0.695 0.305 0.000
S32 Fracture of lumbar spine and pelvis
0.695 0.305 0.000
R46 Symptoms and signs involving appearance and behaviour
0.694 0.305 0.000
R43 Disturbances of smell and taste
0.694 0.305 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.694 0.306 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.694 0.306 0.000
L29 Pruritus
0.693 0.307 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.692 0.308 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
I67.8 Other specified cerebrovascular diseases
0.691 0.308 0.000
Z94 Transplanted organ and tissue status
0.690 0.310 0.000
A07 Other protozoal intestinal diseases
0.689 0.311 0.000
A06 Amoebiasis
0.689 0.311 0.000
A05 Other bacterial foodborne intoxications
0.689 0.311 0.000
A03 Shigellosis
0.689 0.311 0.000
A02 Other Salmonella infections
0.689 0.311 0.000
A01 Typhoid and paratyphoid fevers
0.689 0.311 0.000
A00 Cholera
0.689 0.311 0.000
E00-E07 Disorders of thyroid gland
0.686 0.314 0.000
E34 Other endocrine disorders
0.686 0.314 0.000
I09 Other rheumatic heart diseases
0.686 0.314 0.000
I06 Rheumatic aortic valve diseases
0.686 0.314 0.000
I33 Acute and subacute endocarditis
0.685 0.315 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.685 0.315 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.685 0.315 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.684 0.315 0.000
I73.9 Peripheral vascular disease, unspecified
0.684 0.316 0.000
E27 Other disorders of adrenal gland
0.684 0.316 0.000
N00-N08 Glomerular diseases
0.684 0.316 0.000
Z04.6 General psychiatric examination, requested by authority
0.684 0.316 0.000
Z04.5 Examination and observation following other inflicted injury
0.684 0.316 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.684 0.316 0.000
Z04.2 Examination and observation following work accident
0.684 0.316 0.000
Z04.0 Blood-alcohol and blood-drug test
0.684 0.316 0.000
H25.9 Senile cataract, unspecified
0.683 0.317 0.000
R09.1 Pleurisy
0.683 0.317 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.683 0.317 0.000
F60-F69 Disorders of adult personality and behaviour
0.682 0.318 0.000
J40-J47 Chronic lower respiratory diseases
0.682 0.318 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.681 0.318 0.000
N13 Obstructive and reflux uropathy
0.681 0.319 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.681 0.319 0.000
L65 Other nonscarring hair loss
0.680 0.320 0.000
E40-E46 Malnutrition
0.680 0.320 0.000
L30 Other dermatitis
0.680 0.320 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.680 0.320 0.000
Z93.1 Gastrostomy status
0.680 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.680 0.320 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.680 0.320 0.000
I49.4 Other and unspecified premature depolarisation
0.679 0.321 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.678 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.678 0.322 0.000
I05.2 Mitral stenosis with insufficiency
0.678 0.322 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.677 0.323 0.000
E14 Unspecified diabetes mellitus
0.677 0.323 0.000
Y43.9 Primarily systemic agent, unspecified
0.676 0.324 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.676 0.324 0.000
Y43.6 Enzymes, not elsewhere classified
0.676 0.324 0.000
Y43.5 Acidifying and alkalising agents
0.676 0.324 0.000
Y43.2 Antineoplastic natural products
0.676 0.324 0.000
Y43.0 Antiallergic and antiemetic drugs
0.676 0.324 0.000
I47.2 Ventricular tachycardia
0.675 0.325 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.675 0.325 0.000
Z03.0 Observation for suspected tuberculosis
0.675 0.325 0.000
S00 Superficial injury of head
0.674 0.326 0.000
E88 Other metabolic disorders
0.673 0.327 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.673 0.327 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.327 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.673 0.327 0.000
F33 Recurrent depressive disorder
0.672 0.328 0.000
A49 Bacterial infection of unspecified site
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.671 0.329 0.000
I05.0 Mitral stenosis
0.670 0.330 0.000
J00-J06 Acute upper respiratory infections
0.669 0.331 0.000
S20-S29 Injuries to the thorax
0.669 0.331 0.000
N87 Dysplasia of cervix uteri
0.668 0.332 0.000
H60-H62 Diseases of external ear
0.668 0.332 0.000
E11.5 With peripheral circulatory complications
0.666 0.334 0.000
H51 Other disorders of binocular movement
0.666 0.334 0.000
Y42.9 Other and unspecified hormone antagonists
0.665 0.334 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.665 0.334 0.000
Y42.4 Oral contraceptives
0.665 0.334 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.665 0.334 0.000
Y42.2 Antithyroid drugs
0.665 0.334 0.000
Y42.1 Thyroid hormones and substitutes
0.665 0.334 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.665 0.334 0.000
J39.2 Other diseases of pharynx
0.665 0.335 0.000
N70.1 Chronic salpingitis and oophoritis
0.665 0.335 0.000
B15-B19 Viral hepatitis
0.665 0.335 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.664 0.335 0.000
B48 Other mycoses, not elsewhere classified
0.664 0.336 0.000
B47 Mycetoma
0.664 0.336 0.000
B46 Zygomycosis
0.664 0.336 0.000
B45 Cryptococcosis
0.664 0.336 0.000
B43 Chromomycosis and phaeomycotic abscess
0.664 0.336 0.000
B42 Sporotrichosis
0.664 0.336 0.000
B41 Paracoccidioidomycosis
0.664 0.336 0.000
B40 Blastomycosis
0.664 0.336 0.000
B39 Histoplasmosis
0.664 0.336 0.000
B38 Coccidioidomycosis
0.664 0.336 0.000
B36 Other superficial mycoses
0.664 0.336 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.664 0.336 0.000
Y57 Other and unspecified drugs and medicaments
0.663 0.336 0.000
I49.1 Atrial premature depolarisation
0.663 0.337 0.000
Q28 Other congenital malformations of circulatory system
0.663 0.337 0.000
Q26 Congenital malformations of great veins
0.663 0.337 0.000
Q25 Congenital malformations of great arteries
0.663 0.337 0.000
Q24 Other congenital malformations of heart
0.663 0.337 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.663 0.337 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.663 0.337 0.000
T31 Burns classified according to extent of body surface involved
0.663 0.337 0.000
J30 Vasomotor and allergic rhinitis
0.662 0.338 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.662 0.338 0.000
I78 Diseases of capillaries
0.660 0.340 0.000
R06 Abnormalities of breathing
0.660 0.340 0.000
E29 Testicular dysfunction
0.659 0.341 0.000
A08 Viral and other specified intestinal infections
0.658 0.341 0.000
E23 Hypofunction and other disorders of pituitary gland
0.658 0.342 0.000
T23 Burn and corrosion of wrist and hand
0.658 0.342 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.658 0.342 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.657 0.343 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.657 0.343 0.000
F80-F89 Disorders of psychological development
0.656 0.343 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.656 0.344 0.000
S37 Injury of urinary and pelvic organs
0.656 0.344 0.000
S36 Injury of intra-abdominal organs
0.656 0.344 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.656 0.344 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.656 0.344 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.656 0.344 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.656 0.344 0.000
T39.0 Salicylates
0.655 0.345 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.655 0.345 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.655 0.345 0.000
R04.1 Haemorrhage from throat
0.655 0.345 0.000
Y40 Systemic antibiotics
0.654 0.346 0.000
I15 Secondary hypertension
0.654 0.346 0.000
I30 Acute pericarditis
0.653 0.346 0.000
E26 Hyperaldosteronism
0.653 0.347 0.000
Z03.8 Observation for other suspected diseases and conditions
0.653 0.347 0.000
N60 Benign mammary dysplasia
0.653 0.347 0.000
S62 Fracture at wrist and hand level
0.653 0.347 0.000
Z04.8 Examination and observation for other specified reasons
0.653 0.347 0.000
J39.8 Other specified diseases of upper respiratory tract
0.653 0.347 0.000
Q43 Other congenital malformations of intestine
0.652 0.348 0.000
S50-S59 Injuries to the elbow and forearm
0.652 0.348 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.652 0.348 0.000
N75 Diseases of Bartholin's gland
0.652 0.348 0.000
I45.2 Bifascicular block
0.652 0.348 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.651 0.348 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.651 0.349 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.649 0.351 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.649 0.351 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.649 0.351 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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