TreeWAS – Variant ID: rs74053327

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I10-I15 Hypertensive diseases	0.000	0.308	0.692
I12 Hypertensive renal disease	0.000	0.445	0.555
I13 Hypertensive heart and renal disease	0.000	0.504	0.496
I15 Secondary hypertension	0.000	0.505	0.495
I12.0 Hypertensive renal disease with renal failure	0.000	0.519	0.480
I11 Hypertensive heart disease	0.000	0.529	0.471
I60-I69 Cerebrovascular diseases	0.000	0.574	0.426
Chapter IX Diseases of the circulatory system	0.000	0.584	0.416
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.585	0.415
I65.2 Occlusion and stenosis of carotid artery	0.000	0.592	0.408
I20-I25 Ischaemic heart diseases	0.000	0.606	0.394
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.612	0.388
I63 Cerebral infarction	0.000	0.620	0.380
I25 Chronic ischaemic heart disease	0.000	0.634	0.366
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.644	0.356
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.644	0.356
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.644	0.356
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.644	0.356
I15.9 Seconday hypertension, unspecified	0.000	0.645	0.355
I15.8 Other secondary hypertension	0.000	0.645	0.355
I15.2 Hypertension secondary to endocrine disorders	0.000	0.645	0.355
I15.0 Renovascular hypertension	0.000	0.645	0.355
I61 Intracerebral haemorrhage	0.000	0.647	0.353
I15.1 Hypertension secondary to other renal disorders	0.000	0.647	0.353
I12.9 Hypertensive renal disease without renal failure	0.000	0.652	0.348
I25.5 Ischaemic cardiomyopathy	0.000	0.659	0.341
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.662	0.338
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.667	0.333
I21 Acute myocardial infarction	0.000	0.667	0.333
I69 Sequelae of cerebrovascular disease	0.000	0.670	0.330
I60 Subarachnoid haemorrhage	0.000	0.670	0.330
I21.9 Acute myocardial infarction, unspecified	0.000	0.670	0.330
I63.8 Other cerebral infarction	0.000	0.677	0.323
I67 Other cerebrovascular diseases	0.000	0.677	0.323
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.683	0.317
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.683	0.317
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.688	0.312
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.694	0.306
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.694	0.306
I20 Angina pectoris	0.000	0.696	0.304
I25.2 Old myocardial infarction	0.000	0.696	0.304
I00-I02 Acute rheumatic fever	0.000	0.701	0.299
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.702	0.298
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.702	0.298
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.702	0.298
I65.1 Occlusion and stenosis of basilar artery	0.000	0.702	0.298
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.702	0.298
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.704	0.296
I67.8 Other specified cerebrovascular diseases	0.000	0.707	0.293
I23 Certain current complications following acute myocardial infarction	0.000	0.717	0.283
I20.9 Angina pectoris, unspecified	0.000	0.719	0.281
I22 Subsequent myocardial infarction	0.000	0.719	0.281
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.727	0.273
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.727	0.273
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.727	0.273
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.727	0.273
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.729	0.271
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.730	0.270
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.730	0.270
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.731	0.269
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.735	0.264
I25.6 Silent myocardial ischaemia	0.000	0.737	0.263
I62 Other nontraumatic intracranial haemorrhage	0.000	0.737	0.262
I25.4 Coronary artery aneurysm	0.000	0.742	0.258
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.743	0.257
I24 Other acute ischaemic heart diseases	0.000	0.745	0.255
I61.8 Other intracerebral haemorrhage	0.000	0.746	0.253
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.746	0.253
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.746	0.253
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.746	0.253
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.746	0.253
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.746	0.253
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.748	0.252
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.750	0.250
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.750	0.250
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.753	0.247
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.758	0.242
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.761	0.239
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.763	0.237
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.763	0.237
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.763	0.237
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.763	0.237
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.763	0.237
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.763	0.237
I63.9 Cerebral infarction, unspecified	0.000	0.768	0.232
I67.9 Cerebrovascular disease, unspecified	0.000	0.768	0.232
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.768	0.231
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.768	0.231
I67.5 Moyamoya disease	0.000	0.768	0.231
I67.4 Hypertensive encephalopathy	0.000	0.768	0.231
I67.3 Progressive vascular leukoencephalopathy	0.000	0.768	0.231
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.768	0.231
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.775	0.225
I20.1 Angina pectoris with documented spasm	0.000	0.777	0.223
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.779	0.221
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.779	0.220
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.780	0.219
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.780	0.219
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.780	0.219
I68.0 Cerebral amyloid angiopathy	0.000	0.780	0.219
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.782	0.218
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.784	0.216
I20.8 Other forms of angina pectoris	0.000	0.784	0.216
I02 Rheumatic chorea	0.000	0.786	0.214
I01 Rheumatic fever with heart involvement	0.000	0.786	0.214
I00 Rheumatic fever without mention of heart involvement	0.000	0.786	0.214
I60.8 Other subarachnoid haemorrhage	0.000	0.793	0.206
I67.2 Cerebral atherosclerosis	0.000	0.795	0.204
I69.3 Sequelae of cerebral infarction	0.000	0.796	0.204
I23.8 Other current complications following acute myocardial infarction	0.000	0.797	0.203
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.797	0.203
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.797	0.203
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.797	0.203
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.797	0.203
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.797	0.203
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.797	0.203
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.797	0.203
I22.8 Subsequent myocardial infarction of other sites	0.000	0.799	0.201
I25.3 Aneurysm of heart	0.000	0.800	0.200
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.803	0.197
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.806	0.194
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.806	0.194
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.806	0.194
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.806	0.194
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.806	0.194
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.806	0.194
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.809	0.191
I62.1 Nontraumatic extradural haemorrhage	0.000	0.812	0.188
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.816	0.184
I24.1 Dressler's syndrome	0.000	0.817	0.183
I24.8 Other forms of acute ischaemic heart disease	0.000	0.819	0.181
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.824	0.176
I21.4 Acute subendocardial myocardial infarction	0.000	0.832	0.168
I74 Arterial embolism and thrombosis	0.000	0.834	0.166
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.835	0.165
I05-I09 Chronic rheumatic heart diseases	0.000	0.840	0.160
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.842	0.158
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.846	0.154
I01.8 Other acute rheumatic heart disease	0.000	0.846	0.154
I01.2 Acute rheumatic myocarditis	0.000	0.846	0.154
I01.1 Acute rheumatic endocarditis	0.000	0.846	0.154
I01.0 Acute rheumatic pericarditis	0.000	0.846	0.154
I02.9 Rheumatic chorea without heart involvement	0.000	0.846	0.154
I02.0 Rheumatic chorea with heart involvement	0.000	0.846	0.154
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.851	0.149
I67.1 Cerebral aneurysm, nonruptured	0.000	0.852	0.148
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.855	0.145
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.855	0.145
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.860	0.140
I77 Other disorders of arteries and arterioles	0.000	0.863	0.137
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.866	0.134
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.866	0.134
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.867	0.133
I77.1 Stricture of artery	0.000	0.880	0.120
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.881	0.119
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.881	0.119
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.881	0.119
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.881	0.119
I08 Multiple valve diseases	0.000	0.882	0.118
I70 Atherosclerosis	0.000	0.883	0.117
I74.5 Embolism and thrombosis of iliac artery	0.000	0.883	0.116
I72 Other aneurysm	0.000	0.884	0.116
I06 Rheumatic aortic valve diseases	0.000	0.885	0.114
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.886	0.114
I74.8 Embolism and thrombosis of other arteries	0.000	0.886	0.113
I73 Other peripheral vascular diseases	0.000	0.894	0.106
I28 Other diseases of pulmonary vessels	0.001	0.896	0.104
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.896	0.104
I09 Other rheumatic heart diseases	0.001	0.901	0.099
I77.5 Necrosis of artery	0.000	0.901	0.099
I77.4 Coeliac artery compression syndrome	0.000	0.901	0.099
I77.3 Arterial fibromuscular dysplasia	0.000	0.901	0.099
I77.2 Rupture of artery	0.000	0.901	0.099
I77.0 Arteriovenous fistula, acquired	0.000	0.901	0.099
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.901	0.099
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.902	0.097
I25.1 Atherosclerotic heart disease	0.000	0.904	0.096
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.904	0.096
I79.1 Aortitis in diseases classified elsewhere	0.000	0.904	0.096
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.904	0.096
I82 Other venous embolism and thrombosis	0.000	0.905	0.095
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.905	0.095
I77.6 Arteritis, unspecified	0.000	0.909	0.090
L90.5 Scar conditions and fibrosis of skin	0.000	0.910	0.090
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.910	0.089
I73.9 Peripheral vascular disease, unspecified	0.000	0.911	0.089
I95-I99 Other and unspecified disorders of the circulatory system	0.001	0.912	0.088
I07 Rheumatic tricuspid valve diseases	0.001	0.912	0.087
I70.0 Atherosclerosis of aorta	0.000	0.915	0.085
I72.8 Aneurysm of other specified arteries	0.000	0.915	0.085
I08.9 Multiple valve disease, unspecified	0.000	0.915	0.084
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.915	0.084
I70.9 Generalised and unspecified atherosclerosis	0.000	0.916	0.084
I70.8 Atherosclerosis of other arteries	0.000	0.916	0.084
I72.3 Aneurysm of iliac artery	0.000	0.916	0.084
I87 Other disorders of veins	0.000	0.916	0.084
L90 Atrophic disorders of skin	0.000	0.916	0.084
I72.9 Aneurysm of unspecified site	0.000	0.916	0.083
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.916	0.083
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.916	0.083
I72.2 Aneurysm of renal artery	0.000	0.916	0.083
I72.1 Aneurysm of artery of upper extremity	0.000	0.916	0.083
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.917	0.082
I06.8 Other rheumatic aortic valve diseases	0.000	0.917	0.082
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.917	0.082
I06.1 Rheumatic aortic insufficiency	0.000	0.917	0.082
I06.0 Rheumatic aortic stenosis	0.000	0.917	0.082
I88 Nonspecific lymphadenitis	0.000	0.918	0.082
L90.0 Lichen sclerosus et atrophicus	0.000	0.918	0.082
I89.0 Lymphoedema, not elsewhere classified	0.000	0.918	0.082
I78 Diseases of capillaries	0.000	0.918	0.082
I85 Oesophageal varices	0.000	0.919	0.081
I71 Aortic aneurysm and dissection	0.000	0.919	0.081
I80 Phlebitis and thrombophlebitis	0.000	0.920	0.080
I70.1 Atherosclerosis of renal artery	0.000	0.921	0.079
I77.8 Other specified disorders of arteries and arterioles	0.000	0.923	0.077
I08.8 Other multiple valve diseases	0.000	0.923	0.077
I82.8 Embolism and thrombosis of other specified veins	0.000	0.923	0.077
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.923	0.076
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.925	0.075
I72.0 Aneurysm of carotid artery	0.000	0.925	0.075
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.925	0.075
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.925	0.075
I28.8 Other specified diseases of pulmonary vessels	0.000	0.925	0.075
I28.1 Aneurysm of pulmonary artery	0.000	0.925	0.075
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.925	0.075
I72.4 Aneurysm of artery of lower extremity	0.000	0.926	0.074
I09.8 Other specified rheumatic heart diseases	0.001	0.928	0.071
I09.2 Chronic rheumatic pericarditis	0.001	0.928	0.071
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.928	0.071
I09.0 Rheumatic myocarditis	0.001	0.928	0.071
I89.1 Lymphangitis	0.000	0.930	0.070
I86 Varicose veins of other sites	0.000	0.930	0.070
I81 Portal vein thrombosis	0.000	0.931	0.069
I73.8 Other specified peripheral vascular diseases	0.000	0.931	0.068
I82.3 Embolism and thrombosis of renal vein	0.000	0.931	0.068
I82.2 Embolism and thrombosis of vena cava	0.000	0.931	0.068
I82.1 Thrombophlebitis migrans	0.000	0.931	0.068
I82.0 Budd-Chiari syndrome	0.000	0.931	0.068
I05 Rheumatic mitral valve diseases	0.001	0.932	0.068
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.933	0.067
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.933	0.067
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.934	0.066
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.935	0.065
I20.0 Unstable angina	0.000	0.935	0.065
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.936	0.064
I07.9 Tricuspid valve disease, unspecified	0.001	0.937	0.063
I07.8 Other tricuspid valve diseases	0.001	0.937	0.063
I07.2 Tricuspid stenosis with insufficiency	0.001	0.937	0.063
I07.0 Tricuspid stenosis	0.001	0.937	0.063
I87.1 Compression of vein	0.000	0.937	0.063
I26 Pulmonary embolism	0.001	0.937	0.062
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.937	0.062
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.938	0.062
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.938	0.061
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.939	0.061
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.939	0.061
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.939	0.061
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.939	0.061
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.939	0.061
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.939	0.061
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.939	0.061
I87.9 Disorder of vein, unspecified	0.000	0.940	0.060
I87.0 Postphlebitic syndrome	0.000	0.940	0.060
L90.9 Atrophic disorder of skin, unspecified	0.000	0.940	0.060
L90.8 Other atrophic disorders of skin	0.000	0.940	0.060
L90.6 Striae atrophicae	0.000	0.940	0.060
L90.4 Acrodermatitis chronica atrophicans	0.000	0.940	0.060
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.940	0.060
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.940	0.060
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.940	0.060
I71.0 Dissection of aorta [any part]	0.000	0.940	0.060
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.941	0.059
I88.8 Other nonspecific lymphadenitis	0.000	0.941	0.059
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.941	0.059
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.941	0.059
I78.9 Disease of capillaries, unspecified	0.000	0.941	0.059
I87.8 Other specified disorders of veins	0.000	0.942	0.058
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.942	0.058
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.942	0.058
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.942	0.058
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.942	0.058
I85.0 Oesophageal varices with bleeding	0.000	0.942	0.058
I85.9 Oesophageal varices without bleeding	0.000	0.942	0.058
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.943	0.057
I09.9 Rheumatic heart disease, unspecified	0.001	0.944	0.055
I78.8 Other diseases of capillaries	0.000	0.946	0.054
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.946	0.054
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.946	0.054
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.946	0.053
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.947	0.053
I99 Other and unspecified disorders of circulatory system	0.001	0.947	0.052
I86.8 Varicose veins of other specified sites	0.000	0.948	0.051
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.949	0.051
I08.0 Disorders of both mitral and aortic valves	0.000	0.949	0.050
I86.3 Vulval varices	0.000	0.950	0.050
I86.2 Pelvic varices	0.000	0.950	0.050
I86.0 Sublingual varices	0.000	0.950	0.050
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.950	0.050
I05.8 Other mitral valve diseases	0.001	0.951	0.049
I98 Other disorders of circulatory system in diseases classified elsewhere	0.001	0.951	0.048
I27 Other pulmonary heart diseases	0.001	0.951	0.048
I86.1 Scrotal varices	0.000	0.952	0.048
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.955	0.045
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.955	0.044
I05.2 Mitral stenosis with insufficiency	0.001	0.956	0.043
I05.9 Mitral valve disease, unspecified	0.001	0.957	0.042
I05.1 Rheumatic mitral insufficiency	0.001	0.957	0.042
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.960	0.040
I05.0 Mitral stenosis	0.001	0.960	0.039
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.961	0.038
I97.1 Other functional disturbances following cardiac surgery	0.001	0.961	0.038
I97.0 Postcardiotomy syndrome	0.001	0.961	0.038
I86.4 Gastric varices	0.000	0.962	0.038
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.962	0.038
I07.1 Tricuspid insufficiency	0.001	0.964	0.035
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.001	0.965	0.035
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.965	0.035
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.965	0.035
I98.0 Cardiovascular syphilis	0.001	0.965	0.035
I27.8 Other specified pulmonary heart diseases	0.001	0.965	0.035
I27.1 Kyphoscoliotic heart disease	0.001	0.965	0.035
L85 Other epidermal thickening	0.000	0.965	0.035
L81 Other disorders of pigmentation	0.000	0.965	0.035
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.965	0.034
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.965	0.034
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.966	0.034
I78.1 Naevus, nonneoplastic	0.000	0.966	0.033
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.967	0.033
L85.9 Epidermal thickening, unspecified	0.000	0.968	0.032
I73.0 Raynaud's syndrome	0.000	0.969	0.031
I83 Varicose veins of lower extremities	0.000	0.969	0.030
L84 Corns and callosities	0.000	0.970	0.030
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.970	0.030
L81.9 Disorder of pigmentation, unspecified	0.000	0.971	0.029
L80 Vitiligo	0.000	0.971	0.029
L93 Lupus erythematosus	0.000	0.971	0.029
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.971	0.029
L95 Vasculitis limited to skin, not elsewhere classified	0.000	0.971	0.029
L87 Transepidermal elimination disorders	0.000	0.971	0.029
L88 Pyoderma gangrenosum	0.000	0.971	0.029
L86 Keratoderma in diseases classified elsewhere	0.000	0.971	0.029
L81.4 Other melanin hyperpigmentation	0.000	0.972	0.028
L94 Other localised connective tissue disorders	0.000	0.973	0.027
L83 Acanthosis nigricans	0.000	0.973	0.027
I27.2 Other secondary pulmonary hypertension	0.001	0.973	0.026
L85.3 Xerosis cutis	0.000	0.975	0.025
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.975	0.025
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.975	0.025
L85.0 Acquired ichthyosis	0.000	0.975	0.025
L92.0 Granuloma annulare	0.000	0.975	0.025
L81.8 Other specified disorders of pigmentation	0.000	0.975	0.025
L81.7 Pigmented purpuric dermatosis	0.000	0.975	0.025
L81.6 Other disorders of diminished melanin formation	0.000	0.975	0.025
L81.5 Leukoderma, not elsewhere classified	0.000	0.975	0.025
L81.3 Cafe au lait spots	0.000	0.975	0.025
L81.2 Freckles	0.000	0.975	0.025
L81.1 Chloasma	0.000	0.975	0.025
L81.0 Postinflammatory hyperpigmentation	0.000	0.975	0.025
L89 Decubitus ulcer	0.000	0.975	0.025
L85.8 Other specified epidermal thickening	0.000	0.975	0.025
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.001	0.975	0.024
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.975	0.025
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.975	0.025
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.975	0.025
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.975	0.025
I27.9 Pulmonary heart disease, unspecified	0.001	0.975	0.024
I27.0 Primary pulmonary hypertension	0.001	0.976	0.024
O80.0 Spontaneous vertex delivery	0.023	0.977	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.000	0.977	0.023
R53 Malaise and fatigue	0.000	0.977	0.023
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.978	0.022
L91 Hypertrophic disorders of skin	0.000	0.978	0.022
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.978	0.022
L93.0 Discoid lupus erythematosus	0.000	0.979	0.021
L93.2 Other local lupus erythematosus	0.000	0.979	0.021
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.979	0.021
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.979	0.020
L87.9 Transepidermal elimination disorder, unspecified	0.000	0.979	0.021
L87.8 Other transepidermal elimination disorders	0.000	0.979	0.021
L87.2 Elastosis perforans serpiginosa	0.000	0.979	0.021
L87.1 Reactive perforating collagenosis	0.000	0.979	0.021
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.000	0.979	0.021
L95.9 Vasculitis limited to skin, unspecified	0.000	0.979	0.021
L95.8 Other vasculitis limited to skin	0.000	0.979	0.021
L95.1 Erythema elevatum diutinum	0.000	0.979	0.021
L95.0 Livedoid vasculitis	0.000	0.979	0.021
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.979	0.021
L99.0 Amyloidosis of skin	0.000	0.979	0.021
L94.9 Localised connective tissue disorder, unspecified	0.000	0.980	0.020
L94.8 Other specified localised connective tissue disorders	0.000	0.980	0.020
L94.6 Ainhum	0.000	0.980	0.020
L94.5 Poikiloderma vasculare atrophicans	0.000	0.980	0.020
L94.4 Gottron's papules	0.000	0.980	0.020
L94.3 Sclerodactyly	0.000	0.980	0.020
L94.1 Linear scleroderma	0.000	0.980	0.020
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.980	0.020
L94.0 Localised scleroderma [morphea]	0.000	0.981	0.019
L89.2 Stage III decubitus ulcer	0.000	0.981	0.019
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.981	0.019
L94.2 Calcinosis cutis	0.000	0.981	0.018
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.983	0.017
L98.7 Excessive and redundant skin and subcutaneous tissue	0.000	0.983	0.017
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.000	0.983	0.017
L98.5 Mucinosis of skin	0.000	0.983	0.017
L98.3 Eosinophilic cellulitis [Wells]	0.000	0.983	0.017
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.000	0.983	0.017
L98.1 Factitial dermatitis	0.000	0.983	0.017
L89.1 Stage II decubitus ulcer	0.000	0.984	0.016
L91.0 Keloid scar	0.000	0.984	0.016
L91.9 Hypertrophic disorder of skin, unspecified	0.000	0.984	0.016
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.984	0.016
L89.3 Stage IV decubitus ulcer	0.000	0.984	0.015
L98.4 Chronic ulcer of skin, not elsewhere classified	0.000	0.984	0.016
O80 Single spontaneous delivery	0.014	0.986	0.000
I95 Hypotension	0.000	0.987	0.013
L98.0 Pyogenic granuloma	0.000	0.987	0.013
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.988	0.012
I34 Nonrheumatic mitral valve disorders	0.000	0.989	0.011
I30-I52 Other forms of heart disease	0.000	0.989	0.011
I34.0 Mitral (valve) insufficiency	0.000	0.989	0.011
E78.0 Pure hypercholesterolaemia	0.000	0.989	0.011
R52.1 Chronic intractable pain	0.000	0.989	0.011
I34.1 Mitral (valve) prolapse	0.000	0.990	0.010
R52 Pain, not elsewhere classified	0.000	0.990	0.010
O80.1 Spontaneous breech delivery	0.010	0.990	0.000
I95.0 Idiopathic hypotension	0.000	0.990	0.009
O80.8 Other single spontaneous delivery	0.010	0.990	0.000
S52.6 Fracture of lower end of both ulna and radius	0.010	0.990	0.000
S52 Fracture of forearm	0.010	0.990	0.000
R52.2 Other chronic pain	0.000	0.990	0.010
I46 Cardiac arrest	0.000	0.990	0.009
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.991	0.009
S52.60 Fracture of lower end of both ulna and radius (closed)	0.009	0.991	0.000
I36 Nonrheumatic tricuspid valve disorders	0.000	0.991	0.009
S80 Superficial injury of lower leg	0.009	0.991	0.000
I95.8 Other hypotension	0.001	0.991	0.009
O80.9 Single spontaneous delivery, unspecified	0.009	0.991	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.991	0.009
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.991	0.009
K43.9 Ventral hernia without obstruction or gangrene	0.009	0.991	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.009	0.991	0.000
S52.3 Fracture of shaft of radius	0.009	0.991	0.000
S80.9 Superficial injury of lower leg, unspecified	0.009	0.991	0.000
R52.9 Pain, unspecified	0.000	0.991	0.009
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.991	0.008
S50-S59 Injuries to the elbow and forearm	0.008	0.991	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.992	0.008
I48 Atrial fibrillation and flutter	0.000	0.992	0.008
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.992	0.008
I41 Myocarditis in diseases classified elsewhere	0.000	0.992	0.008
I40 Acute myocarditis	0.000	0.992	0.008
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I37 Pulmonary valve disorders	0.000	0.992	0.008
I32 Pericarditis in diseases classified elsewhere	0.000	0.992	0.008
I38 Endocarditis, valve unspecified	0.000	0.992	0.008
S80.0 Contusion of knee	0.008	0.992	0.000
I95.2 Hypotension due to drugs	0.000	0.992	0.008
L91.8 Other hypertrophic disorders of skin	0.000	0.992	0.008
S56 Injury of muscle and tendon at forearm level	0.008	0.992	0.000
S52.5 Fracture of lower end of radius	0.008	0.992	0.000
S52.30 Fracture of shaft of radius (closed)	0.008	0.992	0.000
O80-O84 Delivery	0.008	0.992	0.000
R50-R69 General symptoms and signs	0.000	0.992	0.008
S80.8 Other superficial injuries of lower leg	0.008	0.992	0.000
S80-S89 Injuries to the knee and lower leg	0.008	0.992	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.008	0.992	0.000
I33 Acute and subacute endocarditis	0.000	0.992	0.008
S52.4 Fracture of shafts of both ulna and radius	0.008	0.992	0.000
I51.7 Cardiomegaly	0.000	0.992	0.008
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.993	0.007
L57.0 Actinic keratosis	0.000	0.993	0.007
S52.1 Fracture of upper end of radius	0.007	0.993	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.993	0.007
S52.2 Fracture of shaft of ulna	0.007	0.993	0.000
I30 Acute pericarditis	0.000	0.993	0.007
R69 Unknown and unspecified causes of morbidity	0.000	0.993	0.007
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.993	0.007
S52.9 Fracture of forearm, part unspecified	0.007	0.993	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.993	0.007
I46.1 Sudden cardiac death, so described	0.000	0.993	0.007
I31 Other diseases of pericardium	0.000	0.993	0.007
R52.0 Acute pain	0.000	0.993	0.007
S52.7 Multiple fractures of forearm	0.007	0.993	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.993	0.007
T79 Certain early complications of trauma, not elsewhere classified	0.007	0.993	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.993	0.007
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.007	0.993	0.000
S52.51 Fracture of lower end of radius (open)	0.007	0.993	0.000
T79-T79 Certain early complications of trauma	0.007	0.993	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.993	0.007
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.993	0.007
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.993	0.007
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.993	0.007
S72.00 Fracture of neck of femur (closed)	0.007	0.993	0.000
S80.7 Multiple superficial injuries of lower leg	0.007	0.993	0.000
S81 Open wound of lower leg	0.007	0.993	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.007	0.993	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations