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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74112468
log Bayes Factor = 12.4362
Chromosome 13   position 90,520,396  (GRCh37) Explore rs74112468 on Ensembl!
Variant rs74112468 is part of Cluster X0170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
M23 Internal derangement of knee
0.996 0.004 0.000
K65-K67 Diseases of peritoneum
0.994 0.006 0.000
K40-K46 Hernia
0.992 0.008 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.991 0.009 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
K43 Ventral hernia
0.986 0.014 0.000
K66 Other disorders of peritoneum
0.986 0.014 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.980 0.020 0.000
K66.0 Peritoneal adhesions
0.980 0.020 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.978 0.022 0.000
K70-K77 Diseases of liver
0.972 0.028 0.000
I51 Complications and ill-defined descriptions of heart disease
0.965 0.035 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.964 0.036 0.000
M15-M19 Arthrosis
0.963 0.037 0.000
M06 Other rheumatoid arthritis
0.961 0.039 0.000
M25 Other joint disorders, not elsewhere classified
0.958 0.042 0.000
I05-I09 Chronic rheumatic heart diseases
0.956 0.044 0.000
M45-M49 Spondylopathies
0.954 0.046 0.000
Chapter I Certain infectious and parasitic diseases
0.950 0.050 0.000
Chapter VII Diseases of the eye and adnexa
0.949 0.051 0.000
M70-M79 Other soft tissue disorders
0.949 0.051 0.000
M06.9 Rheumatoid arthritis, unspecified
0.942 0.058 0.000
I50 Heart failure
0.942 0.058 0.000
K31 Other diseases of stomach and duodenum
0.941 0.059 0.000
I49 Other cardiac arrhythmias
0.940 0.060 0.000
I51.7 Cardiomegaly
0.940 0.060 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
I08 Multiple valve diseases
0.929 0.071 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
M50-M54 Other dorsopathies
0.925 0.075 0.000
M25.7 Osteophyte
0.922 0.078 0.000
B95-B98 Bacterial, viral and other infectious agents
0.911 0.089 0.000
M19 Other arthrosis
0.909 0.091 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.901 0.099 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.899 0.101 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.894 0.106 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.893 0.107 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.890 0.110 0.000
Chapter VIII Diseases of the ear and mastoid process
0.882 0.118 0.000
M17 Gonarthrosis [arthrosis of knee]
0.882 0.118 0.000
K76 Other diseases of liver
0.881 0.119 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.878 0.122 0.000
I47 Paroxysmal tachycardia
0.877 0.123 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.874 0.126 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.873 0.127 0.000
K40 Inguinal hernia
0.871 0.129 0.000
K22 Other diseases of oesophagus
0.870 0.130 0.000
M19.9 Arthrosis, unspecified
0.866 0.134 0.000
K74 Fibrosis and cirrhosis of liver
0.864 0.136 0.000
M10 Gout
0.864 0.136 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.863 0.137 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.863 0.137 0.000
I49.8 Other specified cardiac arrhythmias
0.860 0.140 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.860 0.140 0.000
M77 Other enthesopathies
0.858 0.142 0.000
I35 Nonrheumatic aortic valve disorders
0.853 0.147 0.000
K80 Cholelithiasis
0.853 0.147 0.000
R94 Abnormal results of function studies
0.852 0.148 0.000
K65 Peritonitis
0.851 0.149 0.000
I50.1 Left ventricular failure
0.850 0.150 0.000
R94.5 Abnormal results of liver function studies
0.849 0.151 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.847 0.153 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.846 0.154 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.845 0.155 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.844 0.156 0.000
M48 Other spondylopathies
0.841 0.159 0.000
M54 Dorsalgia
0.839 0.161 0.000
K27 Peptic ulcer, site unspecified
0.837 0.163 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.836 0.164 0.000
L60-L75 Disorders of skin appendages
0.834 0.166 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.826 0.174 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.823 0.177 0.000
H43-H45 Disorders of vitreous body and globe
0.821 0.179 0.000
K25 Gastric ulcer
0.820 0.180 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.819 0.181 0.000
I49.3 Ventricular premature depolarisation
0.818 0.182 0.000
I47.2 Ventricular tachycardia
0.816 0.184 0.000
M24 Other specific joint derangements
0.815 0.185 0.000
K50-K52 Noninfective enteritis and colitis
0.814 0.186 0.000
M25.76 Osteophyte (Lower leg)
0.810 0.190 0.000
K31.8 Other specified diseases of stomach and duodenum
0.808 0.192 0.000
M46 Other inflammatory spondylopathies
0.808 0.192 0.000
I36 Nonrheumatic tricuspid valve disorders
0.808 0.192 0.000
K75 Other inflammatory liver diseases
0.806 0.194 0.000
M23.4 Loose body in knee
0.805 0.195 0.000
K85 Acute pancreatitis
0.805 0.195 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.803 0.197 0.000
M79.8 Other specified soft tissue disorders
0.801 0.199 0.000
M05 Seropositive rheumatoid arthritis
0.800 0.200 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.799 0.201 0.000
M25.77 Osteophyte (Ankle and foot)
0.797 0.203 0.000
Y43 Primarily systemic agents
0.796 0.204 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.795 0.205 0.000
V10-V19 Pedal cyclist injured in transport accident
0.794 0.206 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.793 0.207 0.000
H65-H75 Diseases of middle ear and mastoid
0.792 0.208 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.792 0.208 0.000
M65-M68 Disorders of synovium and tendon
0.788 0.212 0.000
M17.3 Other posttraumatic gonarthrosis
0.788 0.212 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.787 0.213 0.000
M25.78 Osteophyte (Other)
0.787 0.213 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.785 0.215 0.000
I45 Other conduction disorders
0.785 0.215 0.000
Y52 Agents primarily affecting the cardiovascular system
0.784 0.216 0.000
M47 Spondylosis
0.784 0.216 0.000
I50.9 Heart failure, unspecified
0.782 0.218 0.000
M18 Arthrosis of first carpometacarpal joint
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
I77 Other disorders of arteries and arterioles
0.781 0.219 0.000
M17.1 Other primary gonarthrosis
0.778 0.222 0.000
H18 Other disorders of cornea
0.778 0.222 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.776 0.224 0.000
M10.9 Gout, unspecified
0.774 0.226 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.772 0.228 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.770 0.229 0.000
L20-L30 Dermatitis and eczema
0.770 0.230 0.000
D80-D89 Certain disorders involving the immune mechanism
0.770 0.230 0.000
I35.1 Aortic (valve) insufficiency
0.763 0.237 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
K76.8 Other specified diseases of liver
0.760 0.240 0.000
M11 Other crystal arthropathies
0.759 0.241 0.000
K65.0 Acute peritonitis
0.758 0.242 0.000
M20 Acquired deformities of fingers and toes
0.757 0.243 0.000
I42 Cardiomyopathy
0.757 0.243 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.756 0.244 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
K21 Gastro-oesophageal reflux disease
0.755 0.245 0.000
M77.9 Enthesopathy, unspecified
0.753 0.247 0.000
K22.5 Diverticulum of oesophagus, acquired
0.752 0.248 0.000
K42 Umbilical hernia
0.751 0.249 0.000
Q60-Q64 Congenital malformations of the urinary system
0.750 0.250 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.750 0.250 0.000
M48.0 Spinal stenosis
0.749 0.251 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.748 0.252 0.000
K72 Hepatic failure, not elsewhere classified
0.747 0.253 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.747 0.253 0.000
L72.1 Trichilemmal cyst
0.747 0.253 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.746 0.254 0.000
I44 Atrioventricular and left bundle-branch block
0.746 0.254 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.746 0.254 0.000
H52 Disorders of refraction and accommodation
0.744 0.256 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.742 0.258 0.000
I50.0 Congestive heart failure
0.742 0.258 0.000
M50 Cervical disk disorders
0.741 0.259 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.740 0.260 0.000
Chapter V Mental and behavioural disorders
0.740 0.260 0.000
I30 Acute pericarditis
0.739 0.260 0.000
L03 Cellulitis
0.739 0.261 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.736 0.264 0.000
M25.74 Osteophyte (Hand)
0.735 0.265 0.000
M25.8 Other specified joint disorders
0.735 0.265 0.000
K22.1 Ulcer of oesophagus
0.734 0.266 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
M91-M94 Chondropathies
0.733 0.267 0.000
Q80-Q89 Other congenital malformations
0.733 0.267 0.000
K83 Other diseases of biliary tract
0.733 0.267 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.732 0.268 0.000
Y57 Other and unspecified drugs and medicaments
0.732 0.268 0.000
M23.3 Other meniscus derangements
0.731 0.269 0.000
B35-B49 Mycoses
0.731 0.269 0.000
K22.2 Oesophageal obstruction
0.730 0.270 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.730 0.270 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.729 0.271 0.000
W20-W49 Exposure to inanimate mechanical forces
0.729 0.271 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.729 0.271 0.000
I49.9 Cardiac arrhythmia, unspecified
0.727 0.272 0.000
I08.0 Disorders of both mitral and aortic valves
0.727 0.273 0.000
K26 Duodenal ulcer
0.726 0.274 0.000
M54.9 Dorsalgia, unspecified
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.725 0.275 0.000
K74.3 Primary biliary cirrhosis
0.725 0.275 0.000
B15-B19 Viral hepatitis
0.725 0.275 0.000
I31 Other diseases of pericardium
0.724 0.276 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.724 0.276 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.724 0.276 0.000
M45 Ankylosing spondylitis
0.722 0.277 0.000
M25.9 Joint disorder, unspecified
0.722 0.278 0.000
I08.8 Other multiple valve diseases
0.721 0.279 0.000
L05 Pilonidal cyst
0.721 0.279 0.000
Y43.3 Other antineoplastic drugs
0.720 0.280 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.720 0.280 0.000
M07 Psoriatic and enteropathic arthropathies
0.719 0.281 0.000
M13 Other arthritis
0.719 0.281 0.000
M21 Other acquired deformities of limbs
0.719 0.281 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.719 0.281 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.284 0.000
M23.9 Internal derangement of knee, unspecified
0.714 0.285 0.000
M23.5 Chronic instability of knee
0.714 0.285 0.000
M23.1 Discoid meniscus (congenital)
0.714 0.285 0.000
M23.0 Cystic meniscus
0.714 0.285 0.000
M72 Fibroblastic disorders
0.714 0.286 0.000
H43 Disorders of vitreous body
0.714 0.286 0.000
Q00-Q07 Congenital malformations of the nervous system
0.714 0.286 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.713 0.287 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.713 0.287 0.000
K45 Other abdominal hernia
0.711 0.289 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.711 0.289 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.711 0.289 0.000
M54.4 Lumbago with sciatica
0.711 0.289 0.000
M71 Other bursopathies
0.710 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
H40-H42 Glaucoma
0.710 0.290 0.000
M77.4 Metatarsalgia
0.708 0.292 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.707 0.293 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.707 0.293 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.707 0.293 0.000
K43.4 Parastomal hernia with gangrene
0.707 0.293 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.707 0.293 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.707 0.293 0.000
K43.1 Ventral hernia with gangrene
0.707 0.293 0.000
K66.9 Disorder of peritoneum, unspecified
0.707 0.293 0.000
K66.8 Other specified disorders of peritoneum
0.707 0.293 0.000
K66.1 Haemoperitoneum
0.707 0.293 0.000
K22.0 Achalasia of cardia
0.706 0.294 0.000
H80-H83 Diseases of inner ear
0.706 0.294 0.000
I49.4 Other and unspecified premature depolarisation
0.705 0.294 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.703 0.297 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
K82 Other diseases of gallbladder
0.703 0.297 0.000
I72 Other aneurysm
0.702 0.298 0.000
D70 Agranulocytosis
0.701 0.299 0.000
H10-H13 Disorders of conjunctiva
0.700 0.300 0.000
H52.1 Myopia
0.698 0.302 0.000
I51.9 Heart disease, unspecified
0.698 0.302 0.000
M54.1 Radiculopathy
0.697 0.302 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.697 0.303 0.000
M48.06 Spinal stenosis (Lumbar region)
0.697 0.303 0.000
Q21 Congenital malformations of cardiac septa
0.697 0.303 0.000
K77 Liver disorders in diseases classified elsewhere
0.697 0.303 0.000
K73 Chronic hepatitis, not elsewhere classified
0.697 0.303 0.000
K71 Toxic liver disease
0.697 0.303 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.695 0.305 0.000
M51 Other intervertebral disk disorders
0.695 0.305 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.694 0.306 0.000
D55-D59 Haemolytic anaemias
0.694 0.306 0.000
M47.8 Other spondylosis
0.694 0.306 0.000
I51.8 Other ill-defined heart diseases
0.694 0.306 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.693 0.307 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.693 0.307 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.692 0.308 0.000
M35 Other systemic involvement of connective tissue
0.692 0.308 0.000
I51.6 Cardiovascular disease, unspecified
0.692 0.308 0.000
I51.5 Myocardial degeneration
0.692 0.308 0.000
I51.4 Myocarditis, unspecified
0.692 0.308 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.692 0.308 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.692 0.308 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.692 0.308 0.000
I51.0 Cardiac septal defect, acquired
0.692 0.308 0.000
K28 Gastrojejunal ulcer
0.691 0.308 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.691 0.308 0.000
K31.7 Polyp of stomach and duodenum
0.691 0.309 0.000
M15 Polyarthrosis
0.691 0.309 0.000
K41 Femoral hernia
0.690 0.310 0.000
K50 Crohn's disease [regional enteritis]
0.690 0.310 0.000
M06.8 Other specified rheumatoid arthritis
0.689 0.311 0.000
M06.4 Inflammatory polyarthropathy
0.689 0.311 0.000
M06.3 Rheumatoid nodule
0.689 0.311 0.000
M06.2 Rheumatoid bursitis
0.689 0.311 0.000
M06.1 Adult-onset Still's disease
0.689 0.311 0.000
K74.0 Hepatic fibrosis
0.688 0.312 0.000
M25.3 Other instability of joint
0.687 0.313 0.000
M25.2 Flail joint
0.687 0.313 0.000
M25.1 Fistula of joint
0.687 0.313 0.000
M25.0 Haemarthrosis
0.687 0.313 0.000
I09 Other rheumatic heart diseases
0.686 0.314 0.000
I06 Rheumatic aortic valve diseases
0.686 0.314 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.685 0.315 0.000
M22 Disorders of patella
0.685 0.315 0.000
M49 Spondylopathies in diseases classified elsewhere
0.684 0.316 0.000
K85.9 Acute pancreatitis, unspecified
0.684 0.316 0.000
H18.4 Corneal degeneration
0.683 0.317 0.000
K76.6 Portal hypertension
0.683 0.317 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.682 0.318 0.000
M17.0 Primary gonarthrosis, bilateral
0.682 0.318 0.000
B99-B99 Other infectious diseases
0.681 0.319 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.681 0.319 0.000
B65-B83 Helminthiases
0.681 0.319 0.000
B50-B64 Protozoal diseases
0.681 0.319 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.681 0.319 0.000
A80-A89 Viral infections of the central nervous system
0.681 0.319 0.000
A75-A79 Rickettsioses
0.681 0.319 0.000
A70-A74 Other diseases caused by chlamydiae
0.681 0.319 0.000
A65-A69 Other spirochaetal diseases
0.681 0.319 0.000
A20-A28 Certain zoonotic bacterial diseases
0.681 0.319 0.000
A15-A19 Tuberculosis
0.681 0.319 0.000
B91 Sequelae of poliomyelitis
0.681 0.319 0.000
K22.9 Disease of oesophagus, unspecified
0.681 0.319 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.680 0.319 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.679 0.321 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.678 0.322 0.000
M19.1 Posttraumatic arthrosis of other joints
0.678 0.322 0.000
M31 Other necrotising vasculopathies
0.677 0.322 0.000
K74.6 Other and unspecified cirrhosis of liver
0.677 0.323 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.676 0.324 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.676 0.324 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.676 0.324 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.676 0.324 0.000
L03.0 Cellulitis of finger and toe
0.676 0.324 0.000
K31.6 Fistula of stomach and duodenum
0.675 0.325 0.000
K31.4 Gastric diverticulum
0.675 0.325 0.000
K31.3 Pylorospasm, not elsewhere classified
0.675 0.325 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.675 0.325 0.000
K31.0 Acute dilatation of stomach
0.675 0.325 0.000
I49.2 Junctional premature depolarisation
0.674 0.326 0.000
I49.1 Atrial premature depolarisation
0.674 0.326 0.000
M54.3 Sciatica
0.674 0.326 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.673 0.326 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.673 0.327 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.673 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.673 0.327 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.327 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.673 0.327 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.673 0.327 0.000
K51 Ulcerative colitis
0.672 0.328 0.000
I07 Rheumatic tricuspid valve diseases
0.671 0.329 0.000
H16 Keratitis
0.671 0.329 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.671 0.329 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.670 0.330 0.000
X50-X57 Overexertion, travel and privation
0.670 0.330 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
W50-W64 Exposure to animate mechanical forces
0.670 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V40-V49 Car occupant injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.669 0.331 0.000
M23.49 Loose body in knee-Unspec lig/men
0.668 0.332 0.000
I35.8 Other aortic valve disorders
0.668 0.332 0.000
I05 Rheumatic mitral valve diseases
0.667 0.333 0.000
Q24 Other congenital malformations of heart
0.667 0.333 0.000
I08.9 Multiple valve disease, unspecified
0.666 0.334 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.666 0.334 0.000
M20.1 Hallux valgus (acquired)
0.666 0.334 0.000
M06.0 Seronegative rheumatoid arthritis
0.664 0.335 0.000
L27 Dermatitis due to substances taken internally
0.664 0.336 0.000
M53 Other dorsopathies, not elsewhere classified
0.664 0.336 0.000
M67 Other disorders of synovium and tendon
0.664 0.336 0.000
K35-K38 Diseases of appendix
0.663 0.336 0.000
L10-L14 Bullous disorders
0.663 0.336 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.663 0.337 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.663 0.337 0.000
Q27 Other congenital malformations of peripheral vascular system
0.663 0.337 0.000
K31.5 Obstruction of duodenum
0.662 0.338 0.000
M25.79 Osteophyte (Site unspecified)
0.661 0.339 0.000
M25.73 Osteophyte (Forearm)
0.661 0.339 0.000
M25.72 Osteophyte (Upper arm)
0.661 0.339 0.000
M25.70 Osteophyte (Multiple sites)
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
M50.1 Cervical disk disorder with radiculopathy
0.659 0.341 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.658 0.342 0.000
I35.9 Aortic valve disorder, unspecified
0.658 0.342 0.000
Y40 Systemic antibiotics
0.657 0.343 0.000
M23.8 Other internal derangements of knee
0.656 0.344 0.000
I34 Nonrheumatic mitral valve disorders
0.656 0.344 0.000
H65 Nonsuppurative otitis media
0.656 0.344 0.000
M79.7 Fibromyalgia
0.654 0.346 0.000
L03.1 Cellulitis of other parts of limb
0.653 0.347 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.653 0.347 0.000
M19.8 Other specified arthrosis
0.652 0.348 0.000
M19.2 Other secondary arthrosis
0.652 0.348 0.000
K83.0 Cholangitis
0.651 0.349 0.000
K25.4 Chronic or unspecified with haemorrhage
0.651 0.349 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.650 0.350 0.000
M19.0 Primary arthrosis of other joints
0.649 0.351 0.000
K70 Alcoholic liver disease
0.649 0.351 0.000
M70.2 Olecranon bursitis
0.649 0.351 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.649 0.351 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.648 0.352 0.000
Q28 Other congenital malformations of circulatory system
0.647 0.352 0.000
M19.98 Arthrosis, unspecified (Other)
0.647 0.353 0.000
Y59 Other and unspecified vaccines and biological substances
0.646 0.354 0.000
Y58 Bacterial vaccines
0.646 0.354 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.646 0.354 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.646 0.354 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.646 0.354 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
Y48 Anaesthetics and therapeutic gases
0.646 0.354 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.646 0.354 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.646 0.354 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.644 0.356 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.643 0.357 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.642 0.358 0.000
I74 Arterial embolism and thrombosis
0.642 0.358 0.000
I70 Atherosclerosis
0.641 0.359 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.641 0.359 0.000
D80 Immunodeficiency with predominantly antibody defects
0.641 0.359 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.640 0.359 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.640 0.359 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.640 0.359 0.000
I45.1 Other and unspecified right bundle-branch block
0.640 0.360 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.639 0.361 0.000
D75 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
H72 Perforation of tympanic membrane
0.638 0.362 0.000
K75.8 Other specified inflammatory liver diseases
0.637 0.362 0.000
K75.4 Autoimmune hepatitis
0.637 0.363 0.000
L05.0 Pilonidal cyst with abscess
0.637 0.363 0.000
K86 Other diseases of pancreas
0.636 0.364 0.000
H20 Iridocyclitis
0.635 0.365 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.635 0.365 0.000
H74 Other disorders of middle ear and mastoid
0.634 0.365 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.633 0.367 0.000
L50-L54 Urticaria and erythema
0.633 0.367 0.000
I60-I69 Cerebrovascular diseases
0.633 0.367 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.632 0.368 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.632 0.368 0.000
M17.5 Other secondary gonarthrosis
0.632 0.368 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.632 0.368 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.632 0.368 0.000
K76.7 Hepatorenal syndrome
0.631 0.368 0.000
K76.5 Hepatic veno-occlusive disease
0.631 0.368 0.000
K76.4 Peliosis hepatis
0.631 0.368 0.000
K76.3 Infarction of liver
0.631 0.368 0.000
K76.2 Central haemorrhagic necrosis of liver
0.631 0.368 0.000
K76.1 Chronic passive congestion of liver
0.631 0.368 0.000
K46 Unspecified abdominal hernia
0.631 0.369 0.000
I77.1 Stricture of artery
0.631 0.369 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.631 0.369 0.000
M25.71 Osteophyte (Shoulder region)
0.630 0.370 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.629 0.370 0.000
K85.1 Biliary acute pancreatitis
0.629 0.371 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.629 0.371 0.000
H60-H62 Diseases of external ear
0.629 0.371 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.629 0.371 0.000
I47.0 Reentry ventricular arrhythmia
0.629 0.371 0.000
M10.96 Gout, unspecified (Lower leg)
0.629 0.371 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.628 0.372 0.000
R94.4 Abnormal results of kidney function studies
0.627 0.372 0.000
H18.6 Keratoconus
0.627 0.373 0.000
D73 Diseases of spleen
0.625 0.374 0.000
H30-H36 Disorders of choroid and retina
0.625 0.375 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.625 0.375 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.625 0.375 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.625 0.375 0.000
M24.0 Loose body in joint
0.624 0.376 0.000
M25.4 Effusion of joint
0.624 0.376 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.624 0.376 0.000
K22.3 Perforation of oesophagus
0.624 0.376 0.000
M24.2 Disorder of ligament
0.623 0.377 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.621 0.379 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.621 0.379 0.000
H44 Disorders of globe
0.620 0.380 0.000
K74.5 Biliary cirrhosis, unspecified
0.620 0.380 0.000
K74.4 Secondary biliary cirrhosis
0.620 0.380 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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